IMP: Integrative Multi-species Prediction

Saccharomyces cerevisiae

107 known processes

RAD51 (YER095W)

Rad51p

(Aliases: MUT5)

Entrez: 856831
SGD: S000000897
UniProtKB: P25454

Process Predictions
Disease Predictions

RAD51 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
dna recombination	GO:0006310	172	0.993
mitotic recombination	GO:0006312	55	0.984
nuclear division	GO:0000280	263	0.951
dna repair	GO:0006281	236	0.938	Human Mouse Fly
cellular response to dna damage stimulus	GO:0006974	287	0.867	Human Mouse Worm Fly
organelle fission	GO:0048285	272	0.856
meiotic cell cycle process	GO:1903046	229	0.785
reciprocal dna recombination	GO:0035825	54	0.745
reciprocal meiotic recombination	GO:0007131	54	0.741
telomere maintenance	GO:0000723	74	0.707
meiosis i	GO:0007127	92	0.685
double strand break repair via homologous recombination	GO:0000724	54	0.675	Human Mouse Fly
meiotic cell cycle	GO:0051321	272	0.643
negative regulation of macromolecule metabolic process	GO:0010605	375	0.630
telomere maintenance via recombination	GO:0000722	32	0.625
recombinational repair	GO:0000725	64	0.540	Human Mouse Fly
regulation of biological quality	GO:0065008	391	0.422
negative regulation of cellular metabolic process	GO:0031324	407	0.384
double strand break repair via synthesis dependent strand annealing	GO:0045003	12	0.383	Fly
chromosome segregation	GO:0007059	159	0.330	Worm
mitotic nuclear division	GO:0007067	131	0.296
meiotic nuclear division	GO:0007126	163	0.272
single organism developmental process	GO:0044767	258	0.262	Worm Fly
telomere organization	GO:0032200	75	0.255
regulation of response to stimulus	GO:0048583	157	0.244	Human Fly
homeostatic process	GO:0042592	227	0.225
nucleotide metabolic process	GO:0009117	453	0.206
signal transduction	GO:0007165	208	0.199	Worm
mitotic cell cycle process	GO:1903047	294	0.194
organic cyclic compound catabolic process	GO:1901361	499	0.187
mitotic cell cycle phase transition	GO:0044772	141	0.180
nucleoside phosphate metabolic process	GO:0006753	458	0.178
carbohydrate derivative biosynthetic process	GO:1901137	181	0.175
dna recombinase assembly	GO:0000730	9	0.167
protein modification by small protein conjugation or removal	GO:0070647	172	0.157
anatomical structure homeostasis	GO:0060249	74	0.143
cell communication	GO:0007154	345	0.138	Worm
single organism catabolic process	GO:0044712	619	0.136
response to oxidative stress	GO:0006979	99	0.136
mitotic cell cycle	GO:0000278	306	0.133
dna biosynthetic process	GO:0071897	33	0.128
double strand break repair	GO:0006302	105	0.127	Human Mouse Fly
reproduction of a single celled organism	GO:0032505	191	0.126
anatomical structure morphogenesis	GO:0009653	160	0.125	Fly
sister chromatid segregation	GO:0000819	93	0.124
nucleobase containing compound catabolic process	GO:0034655	479	0.119
chromatin organization	GO:0006325	242	0.119
cellular response to oxidative stress	GO:0034599	94	0.118
regulation of dna metabolic process	GO:0051052	100	0.118	Human Fly
mitotic sister chromatid segregation	GO:0000070	85	0.114
dna topological change	GO:0006265	10	0.112
positive regulation of nucleobase containing compound metabolic process	GO:0045935	409	0.111	Human
negative regulation of nitrogen compound metabolic process	GO:0051172	300	0.109
organophosphate metabolic process	GO:0019637	597	0.107
cellular nitrogen compound catabolic process	GO:0044270	494	0.105
oxoacid metabolic process	GO:0043436	351	0.098
generation of precursor metabolites and energy	GO:0006091	147	0.094
cellular macromolecule catabolic process	GO:0044265	363	0.091
carboxylic acid metabolic process	GO:0019752	338	0.090
cell aging	GO:0007569	70	0.089
nucleobase containing small molecule metabolic process	GO:0055086	491	0.089
aging	GO:0007568	71	0.087
oxidation reduction process	GO:0055114	353	0.087
regulation of cell communication	GO:0010646	124	0.087
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	289	0.084
protein dna complex assembly	GO:0065004	105	0.083
cell cycle phase transition	GO:0044770	144	0.082
proteolysis	GO:0006508	268	0.082
heteroduplex formation	GO:0030491	9	0.081
cellular response to chemical stimulus	GO:0070887	315	0.081	Human
response to chemical	GO:0042221	390	0.079	Human Fly
purine containing compound metabolic process	GO:0072521	400	0.075
heterocycle catabolic process	GO:0046700	494	0.075
purine containing compound catabolic process	GO:0072523	332	0.073
replicative cell aging	GO:0001302	46	0.072
reproductive process in single celled organism	GO:0022413	145	0.072
ion transport	GO:0006811	274	0.070
regulation of catabolic process	GO:0009894	199	0.068
cellular response to organic substance	GO:0071310	159	0.068	Human
nucleoside triphosphate metabolic process	GO:0009141	364	0.068
response to organonitrogen compound	GO:0010243	18	0.067	Human Fly
anatomical structure development	GO:0048856	160	0.067	Worm Fly
organic acid metabolic process	GO:0006082	352	0.065
purine nucleoside catabolic process	GO:0006152	330	0.065
lipid metabolic process	GO:0006629	269	0.065
purine nucleotide catabolic process	GO:0006195	328	0.064
aromatic compound catabolic process	GO:0019439	491	0.063
dna geometric change	GO:0032392	43	0.063	Human
positive regulation of macromolecule metabolic process	GO:0010604	394	0.063	Human
atp metabolic process	GO:0046034	251	0.062
nucleic acid phosphodiester bond hydrolysis	GO:0090305	194	0.062
purine nucleoside monophosphate catabolic process	GO:0009128	224	0.062
organophosphate biosynthetic process	GO:0090407	182	0.061
dna replication	GO:0006260	147	0.059	Human
positive regulation of dna metabolic process	GO:0051054	26	0.058	Human
regulation of protein modification process	GO:0031399	110	0.058
developmental process	GO:0032502	261	0.058	Worm Fly
regulation of dna recombination	GO:0000018	24	0.057	Human Fly
positive regulation of biosynthetic process	GO:0009891	336	0.057
carbohydrate metabolic process	GO:0005975	252	0.057
purine ribonucleoside monophosphate catabolic process	GO:0009169	224	0.056
purine nucleoside triphosphate metabolic process	GO:0009144	356	0.055
meiotic chromosome segregation	GO:0045132	31	0.054	Worm
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	137	0.054
modification dependent protein catabolic process	GO:0019941	181	0.054
response to organic substance	GO:0010033	182	0.053	Human Fly
ribonucleoside metabolic process	GO:0009119	389	0.052
response to organic cyclic compound	GO:0014070	1	0.051	Human Fly
negative regulation of gene silencing	GO:0060969	27	0.051
mating type switching	GO:0007533	28	0.050
single organism carbohydrate metabolic process	GO:0044723	237	0.050
anion transmembrane transport	GO:0098656	79	0.050
maintenance of location in cell	GO:0051651	58	0.049
atp catabolic process	GO:0006200	224	0.049
purine ribonucleoside triphosphate metabolic process	GO:0009205	354	0.049
ribonucleoside triphosphate metabolic process	GO:0009199	356	0.048
nucleoside monophosphate catabolic process	GO:0009125	224	0.048
signaling	GO:0023052	208	0.047	Worm
non recombinational repair	GO:0000726	33	0.047
cellular component morphogenesis	GO:0032989	97	0.047
glycosyl compound catabolic process	GO:1901658	335	0.046
positive regulation of nitrogen compound metabolic process	GO:0051173	412	0.046	Human
response to nutrient levels	GO:0031667	150	0.046
carbohydrate derivative metabolic process	GO:1901135	549	0.045
regulation of mitotic cell cycle phase transition	GO:1901990	68	0.045
ribonucleoside triphosphate catabolic process	GO:0009203	327	0.044
negative regulation of nucleobase containing compound metabolic process	GO:0045934	295	0.044
negative regulation of rna biosynthetic process	GO:1902679	260	0.044
cellular developmental process	GO:0048869	191	0.043	Fly
reactive oxygen species metabolic process	GO:0072593	10	0.043
dna conformation change	GO:0071103	98	0.043	Human Worm
protein dna complex subunit organization	GO:0071824	153	0.043
organophosphate catabolic process	GO:0046434	338	0.042
single organism signaling	GO:0044700	208	0.041	Worm
response to reactive oxygen species	GO:0000302	22	0.041
response to oxygen containing compound	GO:1901700	61	0.041	Human
regulation of gene silencing	GO:0060968	41	0.040
cellular lipid metabolic process	GO:0044255	229	0.040
negative regulation of dna metabolic process	GO:0051053	36	0.040
positive regulation of transcription dna templated	GO:0045893	286	0.040
negative regulation of cell communication	GO:0010648	33	0.038
regulation of cell cycle	GO:0051726	195	0.038
organonitrogen compound catabolic process	GO:1901565	404	0.038
ribonucleotide catabolic process	GO:0009261	327	0.038
monocarboxylic acid metabolic process	GO:0032787	122	0.037
ribonucleoside monophosphate catabolic process	GO:0009158	224	0.037
response to abiotic stimulus	GO:0009628	159	0.037	Human
sporulation resulting in formation of a cellular spore	GO:0030435	129	0.037
ribonucleotide metabolic process	GO:0009259	377	0.036
response to inorganic substance	GO:0010035	47	0.036
rna dependent dna replication	GO:0006278	25	0.036
organonitrogen compound biosynthetic process	GO:1901566	314	0.036
regulation of molecular function	GO:0065009	320	0.036
anion transport	GO:0006820	145	0.035
macromolecule catabolic process	GO:0009057	383	0.035
nitrogen compound transport	GO:0071705	212	0.035
purine ribonucleoside triphosphate catabolic process	GO:0009207	327	0.035
sexual sporulation	GO:0034293	113	0.033
purine ribonucleoside monophosphate metabolic process	GO:0009167	262	0.032
regulation of signal transduction	GO:0009966	114	0.031
maintenance of location	GO:0051235	66	0.031
negative regulation of rna metabolic process	GO:0051253	262	0.031
regulation of transport	GO:0051049	85	0.031
positive regulation of nucleic acid templated transcription	GO:1903508	286	0.031
maintenance of protein location	GO:0045185	53	0.030
double strand break repair via single strand annealing	GO:0045002	7	0.030
developmental process involved in reproduction	GO:0003006	159	0.030	Fly
establishment of protein localization	GO:0045184	367	0.029
purine nucleoside monophosphate metabolic process	GO:0009126	262	0.028
cell differentiation	GO:0030154	161	0.028	Fly
organic anion transport	GO:0015711	114	0.028
carbohydrate derivative catabolic process	GO:1901136	339	0.027
multi organism process	GO:0051704	233	0.027	Fly
positive regulation of cellular biosynthetic process	GO:0031328	336	0.027
regulation of mitotic cell cycle	GO:0007346	107	0.027
lipid biosynthetic process	GO:0008610	170	0.026
nucleoside catabolic process	GO:0009164	335	0.026
response to extracellular stimulus	GO:0009991	156	0.026
sulfur compound metabolic process	GO:0006790	95	0.026
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	137	0.026
nucleoside triphosphate catabolic process	GO:0009143	329	0.025
mismatch repair	GO:0006298	14	0.025
purine ribonucleoside catabolic process	GO:0046130	330	0.025
positive regulation of macromolecule biosynthetic process	GO:0010557	325	0.025
cation transport	GO:0006812	166	0.024
cell development	GO:0048468	107	0.024	Fly
nucleoside monophosphate metabolic process	GO:0009123	267	0.024
dna dependent dna replication	GO:0006261	115	0.024	Human
purine nucleoside metabolic process	GO:0042278	380	0.023
negative regulation of nucleic acid templated transcription	GO:1903507	260	0.023
telomere maintenance via telomerase	GO:0007004	21	0.023
telomere maintenance via telomere lengthening	GO:0010833	22	0.023
protein modification by small protein conjugation	GO:0032446	144	0.023
cell wall organization or biogenesis	GO:0071554	190	0.023
nucleoside phosphate catabolic process	GO:1901292	331	0.022
purine ribonucleotide catabolic process	GO:0009154	327	0.022
regulation of protein metabolic process	GO:0051246	237	0.022
microtubule based process	GO:0007017	117	0.022
regulation of dna templated transcription in response to stress	GO:0043620	51	0.022
regulation of cellular protein metabolic process	GO:0032268	232	0.022
nucleoside metabolic process	GO:0009116	394	0.022
regulation of mitosis	GO:0007088	65	0.022
negative regulation of transcription dna templated	GO:0045892	258	0.021
nucleotide catabolic process	GO:0009166	330	0.021
regulation of protein phosphorylation	GO:0001932	75	0.021
response to uv	GO:0009411	4	0.021
ribonucleoside monophosphate metabolic process	GO:0009161	265	0.020
regulation of proteolysis	GO:0030162	44	0.020
dna catabolic process	GO:0006308	42	0.020
protein processing	GO:0016485	64	0.020
phosphorylation	GO:0016310	291	0.020
positive regulation of molecular function	GO:0044093	185	0.019
response to nitrogen compound	GO:1901698	18	0.019	Human Fly
sexual reproduction	GO:0019953	216	0.019	Fly
positive regulation of cell death	GO:0010942	3	0.019
regulation of transcription from rna polymerase ii promoter	GO:0006357	394	0.019
purine ribonucleoside metabolic process	GO:0046128	380	0.018
cellular response to nitrogen compound	GO:1901699	14	0.018	Human
regulation of catalytic activity	GO:0050790	307	0.018
glycosyl compound metabolic process	GO:1901657	398	0.018
cellular amino acid metabolic process	GO:0006520	225	0.018
ion homeostasis	GO:0050801	118	0.018
response to metal ion	GO:0010038	24	0.018
positive regulation of catalytic activity	GO:0043085	178	0.018
sporulation	GO:0043934	132	0.017
cellular amino acid biosynthetic process	GO:0008652	118	0.017
reproductive process	GO:0022414	248	0.017	Fly
purine nucleotide metabolic process	GO:0006163	376	0.017
negative regulation of biosynthetic process	GO:0009890	312	0.017
ascospore formation	GO:0030437	107	0.017
mating type determination	GO:0007531	32	0.017
positive regulation of rna biosynthetic process	GO:1902680	286	0.017
cell division	GO:0051301	205	0.017
maintenance of protein location in cell	GO:0032507	50	0.017
single organism carbohydrate catabolic process	GO:0044724	73	0.016
microtubule cytoskeleton organization	GO:0000226	109	0.016
negative regulation of signaling	GO:0023057	30	0.016
cellular response to extracellular stimulus	GO:0031668	150	0.016
positive regulation of hydrolase activity	GO:0051345	112	0.016
regulation of transcription from rna polymerase ii promoter in response to stress	GO:0043618	51	0.016
positive regulation of transport	GO:0051050	32	0.016
positive regulation of programmed cell death	GO:0043068	3	0.016
regulation of cell cycle phase transition	GO:1901987	70	0.016
proteolysis involved in cellular protein catabolic process	GO:0051603	198	0.016
protein targeting	GO:0006605	272	0.015
purine ribonucleotide metabolic process	GO:0009150	372	0.015
regulation of phosphate metabolic process	GO:0019220	230	0.015
negative regulation of cell cycle process	GO:0010948	86	0.015
regulation of cellular catabolic process	GO:0031329	195	0.015
single organism reproductive process	GO:0044702	159	0.015	Fly
negative regulation of signal transduction	GO:0009968	30	0.014
sexual sporulation resulting in formation of a cellular spore	GO:0043935	113	0.014
multi organism reproductive process	GO:0044703	216	0.014	Fly
sex determination	GO:0007530	32	0.014
dna duplex unwinding	GO:0032508	42	0.014	Human
nucleocytoplasmic transport	GO:0006913	163	0.014
protein ubiquitination	GO:0016567	118	0.014
organic hydroxy compound metabolic process	GO:1901615	125	0.014
positive regulation of intracellular transport	GO:0032388	4	0.014
negative regulation of cellular biosynthetic process	GO:0031327	312	0.014
fungal type cell wall biogenesis	GO:0009272	80	0.014
ribonucleoside catabolic process	GO:0042454	332	0.013
regulation of cellular protein catabolic process	GO:1903362	36	0.013
purine nucleoside triphosphate catabolic process	GO:0009146	329	0.013
sphingolipid metabolic process	GO:0006665	41	0.013
gene silencing	GO:0016458	151	0.013
regulation of response to dna damage stimulus	GO:2001020	17	0.013	Human Fly
carboxylic acid biosynthetic process	GO:0046394	152	0.013
nucleobase containing compound transport	GO:0015931	124	0.013
positive regulation of cellular catabolic process	GO:0031331	128	0.013
negative regulation of mitotic cell cycle phase transition	GO:1901991	57	0.013
response to heat	GO:0009408	69	0.013
rrna metabolic process	GO:0016072	244	0.013
polysaccharide metabolic process	GO:0005976	60	0.013
regulation of signaling	GO:0023051	119	0.013
protein catabolic process	GO:0030163	221	0.013
lipid catabolic process	GO:0016042	33	0.012
response to drug	GO:0042493	41	0.012
cellular response to oxygen containing compound	GO:1901701	43	0.012	Human
death	GO:0016265	30	0.012	Worm
regulation of organelle organization	GO:0033043	243	0.012
protein maturation	GO:0051604	76	0.012
response to endogenous stimulus	GO:0009719	26	0.012	Human Fly
negative regulation of catabolic process	GO:0009895	43	0.012
chromosome separation	GO:0051304	33	0.012
cell wall biogenesis	GO:0042546	93	0.012
negative regulation of cellular protein metabolic process	GO:0032269	85	0.012
cation homeostasis	GO:0055080	105	0.012
positive regulation of apoptotic process	GO:0043065	3	0.012
positive regulation of signal transduction	GO:0009967	20	0.011
response to transition metal nanoparticle	GO:1990267	16	0.011
cell cycle checkpoint	GO:0000075	82	0.011
cellular ion homeostasis	GO:0006873	112	0.011
glucose metabolic process	GO:0006006	65	0.011
negative regulation of macromolecule biosynthetic process	GO:0010558	291	0.011
gene conversion	GO:0035822	14	0.011
amine metabolic process	GO:0009308	51	0.011
regulation of proteasomal ubiquitin dependent protein catabolic process	GO:0032434	30	0.011
protein phosphorylation	GO:0006468	197	0.011
intracellular protein transport	GO:0006886	319	0.011
positive regulation of cellular protein metabolic process	GO:0032270	89	0.011
cellular chemical homeostasis	GO:0055082	123	0.011
protein transport	GO:0015031	345	0.011
response to hydrogen peroxide	GO:0042542	12	0.011
anatomical structure formation involved in morphogenesis	GO:0048646	136	0.010	Fly
regulation of protein localization	GO:0032880	62	0.010
chemical homeostasis	GO:0048878	137	0.010
positive regulation of cytoplasmic transport	GO:1903651	4	0.010
maintenance of dna repeat elements	GO:0043570	20	0.010
chromatin remodeling	GO:0006338	80	0.010
cell surface receptor signaling pathway	GO:0007166	38	0.010

RAD51 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of cellular proliferation	DOID:14566	0	0.015	Human

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