IMP: Integrative Multi-species Prediction

Saccharomyces cerevisiae

101 known processes

DNM1 (YLL001W)

Dnm1p

SGD: S000003924
Entrez: 850686
UniProtKB: P54861

Process Predictions
Disease Predictions

DNM1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
mitochondrion organization	GO:0007005	261	0.834
positive regulation of macromolecule metabolic process	GO:0010604	394	0.794
single organism membrane organization	GO:0044802	275	0.634
membrane organization	GO:0061024	276	0.542
protein complex assembly	GO:0006461	302	0.494
peroxisome organization	GO:0007031	68	0.452
organonitrogen compound biosynthetic process	GO:1901566	314	0.388
regulation of organelle organization	GO:0033043	243	0.363
protein transport	GO:0015031	345	0.342
cellular developmental process	GO:0048869	191	0.325
lipid biosynthetic process	GO:0008610	170	0.321
protein complex biogenesis	GO:0070271	314	0.315
cellular macromolecule catabolic process	GO:0044265	363	0.307
small molecule biosynthetic process	GO:0044283	258	0.305
single organism developmental process	GO:0044767	258	0.260
regulation of cellular protein metabolic process	GO:0032268	232	0.259
cellular amino acid biosynthetic process	GO:0008652	118	0.256
establishment of protein localization to mitochondrion	GO:0072655	63	0.252
positive regulation of hydrolase activity	GO:0051345	112	0.251
phospholipid metabolic process	GO:0006644	125	0.247
mitochondrial genome maintenance	GO:0000002	40	0.246
carboxylic acid biosynthetic process	GO:0046394	152	0.221
regulation of cellular component organization	GO:0051128	334	0.215
anatomical structure development	GO:0048856	160	0.214
establishment of protein localization	GO:0045184	367	0.203
positive regulation of cellular biosynthetic process	GO:0031328	336	0.199
developmental process	GO:0032502	261	0.195
cell aging	GO:0007569	70	0.191
protein targeting to mitochondrion	GO:0006626	56	0.185
protein localization to mitochondrion	GO:0070585	63	0.181
anatomical structure morphogenesis	GO:0009653	160	0.172
positive regulation of nucleobase containing compound metabolic process	GO:0045935	409	0.169
macromolecule catabolic process	GO:0009057	383	0.157
regulation of biological quality	GO:0065008	391	0.154
lipid metabolic process	GO:0006629	269	0.147
positive regulation of catalytic activity	GO:0043085	178	0.145
protein targeting	GO:0006605	272	0.143
membrane fusion	GO:0061025	73	0.139
organelle localization	GO:0051640	128	0.138
mrna metabolic process	GO:0016071	269	0.135
response to chemical	GO:0042221	390	0.134
cell differentiation	GO:0030154	161	0.131
mitochondrial transport	GO:0006839	76	0.129
cellular amino acid metabolic process	GO:0006520	225	0.125
vesicle mediated transport	GO:0016192	335	0.124
positive regulation of apoptotic process	GO:0043065	3	0.113
proteolysis	GO:0006508	268	0.112
organic acid metabolic process	GO:0006082	352	0.111
intracellular protein transport	GO:0006886	319	0.107
positive regulation of biosynthetic process	GO:0009891	336	0.107
positive regulation of nitrogen compound metabolic process	GO:0051173	412	0.107
oxoacid metabolic process	GO:0043436	351	0.106
regulation of catalytic activity	GO:0050790	307	0.104
peptide metabolic process	GO:0006518	28	0.101
nuclear transcribed mrna catabolic process deadenylation dependent decay	GO:0000288	44	0.101
positive regulation of cellular protein metabolic process	GO:0032270	89	0.100
organic acid biosynthetic process	GO:0016053	152	0.097
positive regulation of organelle organization	GO:0010638	85	0.096
carbohydrate derivative metabolic process	GO:1901135	549	0.095
cytoskeleton organization	GO:0007010	230	0.093
actin cytoskeleton organization	GO:0030036	100	0.091
purine ribonucleoside triphosphate metabolic process	GO:0009205	354	0.090
protein localization to membrane	GO:0072657	102	0.090
ion transport	GO:0006811	274	0.090
meiotic cell cycle process	GO:1903046	229	0.089
oxidation reduction process	GO:0055114	353	0.086
electron transport chain	GO:0022900	25	0.085
nucleobase containing compound catabolic process	GO:0034655	479	0.084
nucleoside metabolic process	GO:0009116	394	0.084
replicative cell aging	GO:0001302	46	0.081
organophosphate metabolic process	GO:0019637	597	0.080
positive regulation of cell death	GO:0010942	3	0.080
purine ribonucleoside metabolic process	GO:0046128	380	0.078
positive regulation of cell communication	GO:0010647	28	0.076
ribose phosphate metabolic process	GO:0019693	384	0.075
positive regulation of rna metabolic process	GO:0051254	294	0.075
chemical homeostasis	GO:0048878	137	0.074
maintenance of location	GO:0051235	66	0.074
mitochondrial fission	GO:0000266	7	0.074
protein maturation	GO:0051604	76	0.074
cell communication	GO:0007154	345	0.074
proteolysis involved in cellular protein catabolic process	GO:0051603	198	0.072
mitochondrial membrane organization	GO:0007006	48	0.072
positive regulation of transcription dna templated	GO:0045893	286	0.072
regulation of protein metabolic process	GO:0051246	237	0.071
positive regulation of rna biosynthetic process	GO:1902680	286	0.069
purine ribonucleotide metabolic process	GO:0009150	372	0.069
positive regulation of programmed cell death	GO:0043068	3	0.069
ribonucleotide metabolic process	GO:0009259	377	0.068
carbohydrate derivative biosynthetic process	GO:1901137	181	0.067
autophagy	GO:0006914	106	0.067
regulation of proteolysis	GO:0030162	44	0.066
conjugation with cellular fusion	GO:0000747	106	0.066
establishment of organelle localization	GO:0051656	96	0.065
alpha amino acid biosynthetic process	GO:1901607	91	0.065
carboxylic acid metabolic process	GO:0019752	338	0.064
purine containing compound catabolic process	GO:0072523	332	0.064
purine ribonucleoside catabolic process	GO:0046130	330	0.064
nuclear transcribed mrna catabolic process	GO:0000956	89	0.064
aromatic compound catabolic process	GO:0019439	491	0.063
reproductive process	GO:0022414	248	0.063
positive regulation of protein metabolic process	GO:0051247	93	0.062
cellular amine metabolic process	GO:0044106	51	0.062
purine nucleoside catabolic process	GO:0006152	330	0.062
mitotic cytokinesis	GO:0000281	58	0.062
positive regulation of phosphorus metabolic process	GO:0010562	147	0.062
organic hydroxy compound biosynthetic process	GO:1901617	81	0.061
positive regulation of macromolecule biosynthetic process	GO:0010557	325	0.059
maintenance of location in cell	GO:0051651	58	0.059
single organism membrane fusion	GO:0044801	71	0.059
regulation of mitochondrion organization	GO:0010821	20	0.058
ribonucleoside triphosphate catabolic process	GO:0009203	327	0.057
mitochondrion localization	GO:0051646	29	0.056
positive regulation of signaling	GO:0023056	20	0.055
regulation of signaling	GO:0023051	119	0.055
cellular lipid metabolic process	GO:0044255	229	0.054
transmembrane transport	GO:0055085	349	0.054
phosphatidylinositol metabolic process	GO:0046488	62	0.053
positive regulation of nucleic acid templated transcription	GO:1903508	286	0.053
protein targeting to membrane	GO:0006612	52	0.052
positive regulation of molecular function	GO:0044093	185	0.052
response to external stimulus	GO:0009605	158	0.051
positive regulation of gene expression	GO:0010628	321	0.051
positive regulation of intracellular transport	GO:0032388	4	0.051
purine containing compound metabolic process	GO:0072521	400	0.051
aging	GO:0007568	71	0.050
purine ribonucleoside triphosphate catabolic process	GO:0009207	327	0.050
single organism catabolic process	GO:0044712	619	0.050
cellular nitrogen compound catabolic process	GO:0044270	494	0.048
ribonucleoside metabolic process	GO:0009119	389	0.048
cytokinesis	GO:0000910	92	0.048
modification dependent protein catabolic process	GO:0019941	181	0.047
nucleoside catabolic process	GO:0009164	335	0.046
regulation of dna metabolic process	GO:0051052	100	0.045
rna catabolic process	GO:0006401	118	0.045
regulation of molecular function	GO:0065009	320	0.044
establishment of protein localization to membrane	GO:0090150	99	0.044
ubiquitin dependent protein catabolic process	GO:0006511	181	0.043
cell fate commitment	GO:0045165	32	0.043
organic cyclic compound catabolic process	GO:1901361	499	0.043
glycosyl compound metabolic process	GO:1901657	398	0.043
negative regulation of cellular metabolic process	GO:0031324	407	0.043
regulation of hydrolase activity	GO:0051336	133	0.042
actin filament based process	GO:0030029	104	0.042
vesicle organization	GO:0016050	68	0.041
nucleoside triphosphate metabolic process	GO:0009141	364	0.041
regulation of cellular amine metabolic process	GO:0033238	21	0.041
posttranscriptional regulation of gene expression	GO:0010608	115	0.041
positive regulation of cellular component organization	GO:0051130	116	0.040
anatomical structure formation involved in morphogenesis	GO:0048646	136	0.039
endomembrane system organization	GO:0010256	74	0.039
glycerophospholipid metabolic process	GO:0006650	98	0.039
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	252	0.038
single organism cellular localization	GO:1902580	375	0.037
lipid localization	GO:0010876	60	0.037
histone modification	GO:0016570	119	0.036
positive regulation of phosphate metabolic process	GO:0045937	147	0.036
dicarboxylic acid metabolic process	GO:0043648	20	0.035
heterocycle catabolic process	GO:0046700	494	0.034
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	289	0.034
cell development	GO:0048468	107	0.034
cellular component morphogenesis	GO:0032989	97	0.034
cellular component disassembly	GO:0022411	86	0.034
regulation of cytoskeleton organization	GO:0051493	63	0.034
atp catabolic process	GO:0006200	224	0.033
peroxisome fission	GO:0016559	7	0.033
mitochondrion degradation	GO:0000422	29	0.033
ribonucleoside monophosphate metabolic process	GO:0009161	265	0.033
response to abiotic stimulus	GO:0009628	159	0.032
death	GO:0016265	30	0.032
regulation of phosphorus metabolic process	GO:0051174	230	0.032
negative regulation of cellular biosynthetic process	GO:0031327	312	0.032
protein catabolic process	GO:0030163	221	0.032
nucleoside triphosphate catabolic process	GO:0009143	329	0.031
cellular response to external stimulus	GO:0071496	150	0.031
glycosyl compound catabolic process	GO:1901658	335	0.030
negative regulation of macromolecule metabolic process	GO:0010605	375	0.030
reproduction of a single celled organism	GO:0032505	191	0.030
response to extracellular stimulus	GO:0009991	156	0.029
covalent chromatin modification	GO:0016569	119	0.029
purine nucleoside triphosphate metabolic process	GO:0009144	356	0.029
regulation of actin cytoskeleton organization	GO:0032956	31	0.029
sexual sporulation resulting in formation of a cellular spore	GO:0043935	113	0.028
ribonucleoside triphosphate metabolic process	GO:0009199	356	0.028
regulation of dna dependent dna replication	GO:0090329	37	0.028
purine nucleoside metabolic process	GO:0042278	380	0.027
atp metabolic process	GO:0046034	251	0.027
organonitrogen compound catabolic process	GO:1901565	404	0.027
organelle fission	GO:0048285	272	0.027
response to inorganic substance	GO:0010035	47	0.027
cellular ion homeostasis	GO:0006873	112	0.027
glycerolipid biosynthetic process	GO:0045017	71	0.026
cellular homeostasis	GO:0019725	138	0.026
nucleotide metabolic process	GO:0009117	453	0.026
mitochondrion inheritance	GO:0000001	21	0.026
cell death	GO:0008219	30	0.025
protein processing	GO:0016485	64	0.025
nucleotide catabolic process	GO:0009166	330	0.025
translation	GO:0006412	230	0.025
regulation of transport	GO:0051049	85	0.025
ion homeostasis	GO:0050801	118	0.025
purine nucleoside triphosphate catabolic process	GO:0009146	329	0.025
ribonucleoside catabolic process	GO:0042454	332	0.025
multi organism reproductive process	GO:0044703	216	0.024
positive regulation of intracellular protein transport	GO:0090316	3	0.024
cellular response to extracellular stimulus	GO:0031668	150	0.024
nucleobase containing small molecule metabolic process	GO:0055086	491	0.024
glycerolipid metabolic process	GO:0046486	108	0.024
regulation of phosphate metabolic process	GO:0019220	230	0.024
alcohol biosynthetic process	GO:0046165	75	0.024
sexual sporulation	GO:0034293	113	0.023
nucleoside monophosphate metabolic process	GO:0009123	267	0.023
organophosphate catabolic process	GO:0046434	338	0.023
negative regulation of biosynthetic process	GO:0009890	312	0.022
cellular response to organic substance	GO:0071310	159	0.022
cytoskeleton dependent cytokinesis	GO:0061640	65	0.022
cellular protein complex assembly	GO:0043623	209	0.022
regulation of transferase activity	GO:0051338	83	0.021
purine ribonucleoside monophosphate metabolic process	GO:0009167	262	0.021
phosphorylation	GO:0016310	291	0.021
purine ribonucleoside monophosphate catabolic process	GO:0009169	224	0.021
regulation of cell communication	GO:0010646	124	0.020
positive regulation of transport	GO:0051050	32	0.020
golgi vesicle transport	GO:0048193	188	0.020
ribonucleoprotein complex subunit organization	GO:0071826	152	0.020
alpha amino acid metabolic process	GO:1901605	124	0.019
organic anion transport	GO:0015711	114	0.019
sporulation resulting in formation of a cellular spore	GO:0030435	129	0.019
negative regulation of proteolysis	GO:0045861	33	0.019
ascospore formation	GO:0030437	107	0.019
multi organism process	GO:0051704	233	0.019
response to pheromone involved in conjugation with cellular fusion	GO:0000749	74	0.019
purine nucleotide catabolic process	GO:0006195	328	0.018
regulation of actin filament based process	GO:0032970	31	0.018
membrane budding	GO:0006900	22	0.018
regulation of response to external stimulus	GO:0032101	20	0.018
phospholipid biosynthetic process	GO:0008654	89	0.018
intracellular signal transduction	GO:0035556	112	0.018
lipid modification	GO:0030258	37	0.018
purine nucleotide metabolic process	GO:0006163	376	0.018
carbohydrate derivative catabolic process	GO:1901136	339	0.017
homeostatic process	GO:0042592	227	0.017
ribonucleoside monophosphate catabolic process	GO:0009158	224	0.017
cellular chemical homeostasis	GO:0055082	123	0.017
chromatin modification	GO:0016568	200	0.017
regulation of dna replication	GO:0006275	51	0.017
regulation of cellular localization	GO:0060341	50	0.017
protein localization to organelle	GO:0033365	337	0.016
sporulation	GO:0043934	132	0.016
negative regulation of macromolecule biosynthetic process	GO:0010558	291	0.016
regulation of phosphorylation	GO:0042325	86	0.016
ion transmembrane transport	GO:0034220	200	0.016
secretion by cell	GO:0032940	50	0.016
steroid metabolic process	GO:0008202	47	0.016
cellular protein catabolic process	GO:0044257	213	0.016
chromatin organization	GO:0006325	242	0.016
regulation of lipid metabolic process	GO:0019216	45	0.016
lipid transport	GO:0006869	58	0.016
phosphatidylcholine metabolic process	GO:0046470	20	0.015
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	137	0.015
phosphatidylcholine biosynthetic process	GO:0006656	18	0.015
cellular modified amino acid metabolic process	GO:0006575	51	0.015
regulation of cellular protein catabolic process	GO:1903362	36	0.015
proteasomal protein catabolic process	GO:0010498	141	0.014
chronological cell aging	GO:0001300	28	0.014
guanosine containing compound metabolic process	GO:1901068	111	0.014
endocytosis	GO:0006897	90	0.014
positive regulation of mitochondrion organization	GO:0010822	16	0.014
regulation of intracellular transport	GO:0032386	26	0.014
ribonucleotide catabolic process	GO:0009261	327	0.014
response to metal ion	GO:0010038	24	0.014
regulation of protein targeting	GO:1903533	10	0.014
purine containing compound biosynthetic process	GO:0072522	53	0.014
cellular biogenic amine metabolic process	GO:0006576	37	0.014
signaling	GO:0023052	208	0.013
purine nucleoside monophosphate catabolic process	GO:0009128	224	0.013
positive regulation of secretion	GO:0051047	2	0.013
protein transmembrane transport	GO:0071806	82	0.013
meiosis i	GO:0007127	92	0.013
glycerophospholipid biosynthetic process	GO:0046474	68	0.013
dna recombination	GO:0006310	172	0.013
organophosphate ester transport	GO:0015748	45	0.013
response to drug	GO:0042493	41	0.013
positive regulation of cellular amine metabolic process	GO:0033240	10	0.012
regulation of translation	GO:0006417	89	0.012
mrna catabolic process	GO:0006402	93	0.012
fatty acid biosynthetic process	GO:0006633	22	0.012
regulation of protein processing	GO:0070613	34	0.012
establishment of protein localization to organelle	GO:0072594	278	0.012
developmental process involved in reproduction	GO:0003006	159	0.012
ribose phosphate biosynthetic process	GO:0046390	50	0.012
positive regulation of cellular catabolic process	GO:0031331	128	0.011
phosphatidylinositol biosynthetic process	GO:0006661	39	0.011
positive regulation of phosphorylation	GO:0042327	33	0.011
response to transition metal nanoparticle	GO:1990267	16	0.011
glutamine family amino acid metabolic process	GO:0009064	31	0.011
positive regulation of cytokinesis	GO:0032467	2	0.011
alcohol metabolic process	GO:0006066	112	0.011
cellular response to pheromone	GO:0071444	88	0.011
negative regulation of transcription dna templated	GO:0045892	258	0.011
cation homeostasis	GO:0055080	105	0.011
protein modification by small protein removal	GO:0070646	29	0.011
regulation of lipid biosynthetic process	GO:0046890	32	0.011
response to nutrient levels	GO:0031667	150	0.010
macroautophagy	GO:0016236	55	0.010
sulfur compound metabolic process	GO:0006790	95	0.010
gtp metabolic process	GO:0046039	107	0.010
conjugation	GO:0000746	107	0.010
nucleoside phosphate catabolic process	GO:1901292	331	0.010
positive regulation of catabolic process	GO:0009896	135	0.010
amine metabolic process	GO:0009308	51	0.010
purine ribonucleotide catabolic process	GO:0009154	327	0.010
ethanolamine containing compound metabolic process	GO:0042439	21	0.010
thioester metabolic process	GO:0035383	13	0.010
cation transport	GO:0006812	166	0.010
negative regulation of rna metabolic process	GO:0051253	262	0.010

DNM1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.052
disease of metabolism	DOID:0014667	0.024
inherited metabolic disorder	DOID:655	0.024
nervous system disease	DOID:863	0.012

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