Drosophila melanogaster

111 known processes

MBD-R2 (Dmel_CG10042)

CG10042 gene product from transcript CG10042-RB

(Aliases: MBD,MBDR2,CG10042,TAM3,Dm Tam3,CG17393,dMBD-R2,Dmel\CG10042)

MBD-R2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular response to dna damage stimulusGO:00069742230.520
g2 dna damage checkpointGO:0031572690.402
centrosome organizationGO:00512971630.314
mitotic dna damage checkpointGO:0044773740.303
mrna metabolic processGO:00160711240.271
positive regulation of macromolecule metabolic processGO:00106044050.239
regulation of cell cycle phase transitionGO:19019871300.232
chromatin organizationGO:00063252070.230
negative regulation of cell cycle phase transitionGO:19019881030.212
cellular protein modification processGO:00064644380.194
microtubule organizing center organizationGO:00310231680.183
chromosome organizationGO:00512763600.153
mitotic cell cycle phase transitionGO:00447721380.138
cell cycle phase transitionGO:00447701400.133
negative regulation of mitotic cell cycle phase transitionGO:19019911030.124
protein modification processGO:00362114380.120
body morphogenesisGO:001017120.116
negative regulation of cell cycleGO:00457861160.098
regulation of cell cycle processGO:00105641810.098
covalent chromatin modificationGO:00165691060.097
ras protein signal transductionGO:0007265880.095
chromatin remodelingGO:0006338720.094
regulation of small gtpase mediated signal transductionGO:0051056930.089
chromatin modificationGO:00165681470.089
positive regulation of nitrogen compound metabolic processGO:00511733540.089
negative regulation of cell cycle processGO:00109481090.085
histone modificationGO:00165701060.083
aromatic compound catabolic processGO:00194391660.080
catabolic processGO:00090564090.076
regulation of mitotic cell cycle phase transitionGO:19019901300.073
negative regulation of cellular metabolic processGO:00313243820.072
small gtpase mediated signal transductionGO:0007264880.070
purine ribonucleoside monophosphate catabolic processGO:0009169380.069
heterocycle catabolic processGO:00467001660.064
dendrite developmentGO:00163582040.063
organic substance catabolic processGO:19015753080.062
mitotic dna integrity checkpointGO:0044774750.061
regulation of ras protein signal transductionGO:0046578930.060
nucleobase containing compound catabolic processGO:00346551650.057
cellular nitrogen compound catabolic processGO:00442701650.055
mitotic g2 dna damage checkpointGO:0007095690.053
cell cycle checkpointGO:0000075950.051
cellular catabolic processGO:00442483720.049
rna processingGO:00063961470.049
cellular macromolecule catabolic processGO:00442651360.047
spindle elongationGO:0051231830.045
regulation of neuron differentiationGO:00456641030.045
regulation of nervous system developmentGO:00519602480.040
regulation of neurogenesisGO:00507671580.040
regulation of multicellular organismal developmentGO:20000264140.040
regulation of chromosome organizationGO:0033044640.039
dna damage checkpointGO:0000077780.039
regulation of phosphorus metabolic processGO:00511742100.037
purine containing compound metabolic processGO:00725211550.037
negative regulation of rna metabolic processGO:00512532510.036
regulation of mitotic cell cycleGO:00073461900.036
glycosyl compound catabolic processGO:19016581120.034
organelle fissionGO:00482853400.034
cell proliferationGO:00082832990.033
cytoplasmic transportGO:00164821300.033
positive regulation of rna biosynthetic processGO:19026802660.033
centrosome duplicationGO:00512981210.032
nucleobase containing small molecule metabolic processGO:00550861740.032
regulation of phosphate metabolic processGO:00192202100.032
immune system processGO:00023763470.032
regulation of cellular protein metabolic processGO:00322682430.032
phosphorylationGO:00163102940.032
telomere organizationGO:0032200210.032
mitotic cell cycle checkpointGO:0007093880.032
dna biosynthetic processGO:0071897240.031
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.031
regulation of molecular functionGO:00650092170.030
regulation of cell cycleGO:00517262910.030
purine nucleotide metabolic processGO:00061631460.029
ribonucleoside catabolic processGO:00424541120.029
regulation of phosphorylationGO:00423251470.029
mitotic spindle elongationGO:0000022810.029
dna replicationGO:0006260480.029
carbohydrate derivative metabolic processGO:19011352170.028
regulation of mrna processingGO:0050684710.028
peptidyl amino acid modificationGO:00181931050.027
protein localizationGO:00081042840.027
anatomical structure homeostasisGO:0060249970.027
negative regulation of nucleobase containing compound metabolic processGO:00459342610.027
purine nucleotide catabolic processGO:00061951090.027
purine ribonucleoside monophosphate metabolic processGO:0009167500.026
purine ribonucleotide metabolic processGO:00091501450.026
organonitrogen compound metabolic processGO:19015643180.026
nuclear divisionGO:00002803320.025
organonitrogen compound catabolic processGO:19015651280.025
regulation of transcription from rna polymerase ii promoterGO:00063573780.025
centrosome cycleGO:00070981370.025
axon developmentGO:00615642970.024
ribonucleoside monophosphate catabolic processGO:0009158390.024
ribonucleoside triphosphate metabolic processGO:00091991190.024
proteolysisGO:00065081920.024
glycosyl compound metabolic processGO:19016571270.023
spindle organizationGO:00070512530.023
nucleoside phosphate metabolic processGO:00067531620.023
regulation of cell developmentGO:00602842150.023
phagocytosisGO:00069092150.023
establishment of localization in cellGO:00516494020.023
rna polyadenylationGO:0043631120.023
purine nucleoside catabolic processGO:00061521120.022
dna repairGO:0006281540.022
protein ubiquitinationGO:0016567700.022
multi multicellular organism processGO:00447061230.021
regulation of anatomical structure morphogenesisGO:00226032420.021
positive regulation of rna metabolic processGO:00512542710.021
regulation of intracellular signal transductionGO:19025312360.021
nucleoside metabolic processGO:00091161270.021
organic cyclic compound catabolic processGO:19013611680.021
negative regulation of macromolecule biosynthetic processGO:00105582700.021
telomere maintenanceGO:0000723210.021
negative regulation of rna biosynthetic processGO:19026792400.021
protein catabolic processGO:00301631010.020
purine nucleoside metabolic processGO:00422781270.020
nucleoside triphosphate metabolic processGO:00091411200.020
organophosphate metabolic processGO:00196371950.020
purine ribonucleotide catabolic processGO:00091541090.020
negative regulation of response to stimulusGO:00485852580.020
purine ribonucleoside metabolic processGO:00461281270.020
dna integrity checkpointGO:0031570810.020
agingGO:00075681430.020
intracellular signal transductionGO:00355563000.019
nucleotide catabolic processGO:00091661090.018
purine ribonucleoside triphosphate catabolic processGO:00092071080.018
embryo development ending in birth or egg hatchingGO:00097921520.018
positive regulation of catabolic processGO:00098961050.018
sex differentiationGO:0007548810.017
axonogenesisGO:00074092900.017
regulation of localizationGO:00328792750.017
signal transduction by phosphorylationGO:00230141070.017
male gamete generationGO:00482322010.017
cellular macromolecular complex assemblyGO:00346221530.017
ribonucleoside metabolic processGO:00091191270.017
positive regulation of gene expressionGO:00106282900.016
positive regulation of cellular biosynthetic processGO:00313283160.016
central nervous system developmentGO:00074172010.016
dendrite morphogenesisGO:00488131990.016
regulation of neuron projection developmentGO:0010975690.016
regulation of cell proliferationGO:00421271630.016
negative regulation of biosynthetic processGO:00098902770.016
erk1 and erk2 cascadeGO:0070371390.016
nucleocytoplasmic transportGO:0006913720.016
ribonucleotide metabolic processGO:00092591450.016
protein complex biogenesisGO:00702712010.016
regulation of protein modification processGO:00313991120.016
purine nucleoside monophosphate metabolic processGO:0009126500.016
carbohydrate derivative catabolic processGO:19011361180.016
multicellular organismal agingGO:00102591400.015
positive regulation of erk1 and erk2 cascadeGO:0070374360.015
posttranscriptional regulation of gene expressionGO:00106081450.015
positive regulation of response to stimulusGO:00485843230.015
peptide metabolic processGO:0006518800.015
dna metabolic processGO:00062592270.015
ribonucleoside monophosphate metabolic processGO:0009161510.015
regulation of catabolic processGO:00098941700.015
response to organic substanceGO:00100332840.015
cellular amide metabolic processGO:0043603800.015
negative regulation of cell differentiationGO:00455961430.014
cellular macromolecule localizationGO:00707272200.014
positive regulation of intracellular signal transductionGO:19025331160.014
nucleoside triphosphate catabolic processGO:00091431080.014
regulation of erk1 and erk2 cascadeGO:0070372390.014
single organism catabolic processGO:00447122280.014
macromolecule catabolic processGO:00090571610.014
modification dependent protein catabolic processGO:0019941780.014
regulation of intracellular protein transportGO:0033157460.014
positive regulation of phosphorus metabolic processGO:00105621390.013
positive regulation of cell communicationGO:00106472500.013
positive regulation of signalingGO:00230562430.013
protein dna complex subunit organizationGO:0071824860.013
rna 3 end processingGO:0031123450.013
protein processingGO:0016485680.013
atp metabolic processGO:0046034490.013
purine ribonucleoside triphosphate metabolic processGO:00092051190.013
negative regulation of nucleic acid templated transcriptionGO:19035072400.013
negative regulation of cell communicationGO:00106482230.013
mrna processingGO:00063971040.013
determination of adult lifespanGO:00083401370.013
negative regulation of mitotic cell cycleGO:00459301090.013
protein complex assemblyGO:00064612000.012
anterior posterior pattern specificationGO:00099521360.012
positive regulation of cellular amine metabolic processGO:003324000.012
ribonucleotide catabolic processGO:00092611090.012
macromolecular complex assemblyGO:00650032560.012
photoreceptor cell developmentGO:0042461960.012
atp dependent chromatin remodelingGO:0043044220.012
maternal determination of anterior posterior axis embryoGO:0008358740.012
hematopoietic stem cell differentiationGO:006021810.012
regulation of dna repairGO:000628250.012
dna dependent dna replication maintenance of fidelityGO:004500500.012
regulation of mrna metabolic processGO:1903311720.012
negative regulation of cellular biosynthetic processGO:00313272770.012
negative regulation of developmental processGO:00510932010.012
brain developmentGO:00074201200.012
cell deathGO:00082192790.012
centriole replicationGO:0007099240.011
small molecule metabolic processGO:00442813050.011
regulation of apoptotic processGO:00429811300.011
cellular component disassemblyGO:0022411460.011
cellular protein localizationGO:00346131600.011
regulation of cell deathGO:00109411730.011
mitotic sister chromatid segregationGO:0000070870.011
intracellular transportGO:00469072280.011
protein phosphorylationGO:00064681690.011
regulation of catalytic activityGO:00507901850.011
negative regulation of erk1 and erk2 cascadeGO:007037330.011
rrna processingGO:000636430.011
response to oxygen containing compoundGO:19017002000.011
macromolecule methylationGO:0043414450.011
positive regulation of mapk cascadeGO:0043410630.011
ubiquitin homeostasisGO:001099210.011
cell maturationGO:00484691440.010
ubiquitin dependent protein catabolic processGO:0006511780.010
muscle structure developmentGO:00610612240.010
multicellular organism growthGO:0035264460.010
eye photoreceptor cell developmentGO:0042462810.010

MBD-R2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.043
nervous system diseaseDOID:86300.020