IMP: Integrative Multi-species Prediction

Drosophila melanogaster

202 known processes

Mekk1 (Dmel_CG7717)

CG7717 gene product from transcript CG7717-RB

(Aliases: mekk1,CG7717,Mekk1/4,Dmel\CG7717,MEKK,dMEKK1,DmMEKK1,MEKK1,dMEKK4,MEKK4,D-Mekk1,mekk1a,dMekk1,mekk1b,D-MEKK1,dMEKK)

FLYBASE: FBgn0024329
Entrez: 42253
UniProtKB: Q8MSQ4
UniProtKB: Q9VE37

Process Predictions
Disease Predictions

Mekk1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

Filter by process size:

Biological process	GO term ID	Process size	Probability	Func Analog Org
cellular response to heat	GO:0034605	24	0.992
positive regulation of secretion	GO:0051047	22	0.805
response to abiotic stimulus	GO:0009628	341	0.787
response to glucose	GO:0009749	2	0.718
regionalization	GO:0003002	416	0.702
adult chitin containing cuticle pigmentation	GO:0048085	16	0.699
heterochromatin organization	GO:0070828	25	0.687
innate immune response	GO:0045087	144	0.661
intracellular signal transduction	GO:0035556	300	0.652
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.613
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.612
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.607
protein modification process	GO:0036211	438	0.578
immune response	GO:0006955	246	0.568
response to starvation	GO:0042594	97	0.558
negative regulation of biosynthetic process	GO:0009890	277	0.552
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.551
positive regulation of autophagy	GO:0010508	21	0.535
multicellular organismal aging	GO:0010259	140	0.531
regulation of cell death	GO:0010941	173	0.514
mucosal immune response	GO:0002385	10	0.482
wing disc morphogenesis	GO:0007472	344	0.473
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.470
negative regulation of rna biosynthetic process	GO:1902679	240	0.441
negative regulation of cell communication	GO:0010648	223	0.429
negative regulation of transcription dna templated	GO:0045892	237	0.427
regulation of response to biotic stimulus	GO:0002831	63	0.427
regulation of response to stress	GO:0080134	200	0.413
response to salt stress	GO:0009651	11	0.406
regulation of response to oxidative stress	GO:1902882	4	0.400
response to organic substance	GO:0010033	284	0.400
positive regulation of immune response	GO:0050778	63	0.394
chitin based cuticle sclerotization	GO:0007593	19	0.385
regulation of chitin based cuticle tanning	GO:0007564	14	0.383
positive regulation of biosynthetic process	GO:0009891	316	0.366
response to oxidative stress	GO:0006979	86	0.366
positive regulation of protein metabolic process	GO:0051247	128	0.362
response to organic cyclic compound	GO:0014070	89	0.359
negative regulation of cellular metabolic process	GO:0031324	382	0.353
response to oxygen radical	GO:0000305	3	0.353
negative regulation of cellular biosynthetic process	GO:0031327	277	0.343
homeostatic process	GO:0042592	199	0.342
small molecule metabolic process	GO:0044281	305	0.340
regulation of cellular response to oxidative stress	GO:1900407	4	0.336
positive regulation of transport	GO:0051050	92	0.336
regulation of immune effector process	GO:0002697	52	0.335
positive regulation of macromolecule metabolic process	GO:0010604	405	0.317
negative regulation of multicellular organismal process	GO:0051241	142	0.316
embryonic morphogenesis	GO:0048598	206	0.309
aging	GO:0007568	143	0.308
cellular response to cadmium ion	GO:0071276	6	0.300
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.295
regulation of secretion	GO:0051046	44	0.293
lipid metabolic process	GO:0006629	121	0.291
regulation of intracellular signal transduction	GO:1902531	236	0.289
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.289
regulation of adult chitin containing cuticle pigmentation	GO:0048082	13	0.289
localization of cell	GO:0051674	257	0.289
macromolecular complex assembly	GO:0065003	256	0.288
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.282
digestive tract development	GO:0048565	149	0.279
immune system process	GO:0002376	347	0.279
regulation of immune response	GO:0050776	118	0.268
negative regulation of rna metabolic process	GO:0051253	251	0.263
single organism behavior	GO:0044708	391	0.259
lipid modification	GO:0030258	24	0.255
negative regulation of gene expression	GO:0010629	387	0.255
epiboly involved in wound healing	GO:0090505	2	0.255
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.253
response to osmotic stress	GO:0006970	14	0.253
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.250
response to heat	GO:0009408	63	0.249
positive regulation of cellular protein metabolic process	GO:0032270	118	0.245
positive regulation of cellular biosynthetic process	GO:0031328	316	0.242
negative regulation of developmental process	GO:0051093	201	0.238
cellular amide metabolic process	GO:0043603	80	0.230
positive regulation of signal transduction	GO:0009967	223	0.224
response to alkaloid	GO:0043279	26	0.222
establishment of localization in cell	GO:0051649	402	0.219
regulation of secretion by cell	GO:1903530	39	0.215
negative regulation of response to stimulus	GO:0048585	258	0.215
ovarian follicle cell development	GO:0030707	248	0.215
regulation of immune system process	GO:0002682	176	0.212
melanization defense response	GO:0035006	45	0.210
positive regulation of secretion by cell	GO:1903532	20	0.205
positive regulation of signaling	GO:0023056	243	0.204
molting cycle chitin based cuticle	GO:0007591	56	0.203
larval development	GO:0002164	104	0.201
positive regulation of defense response	GO:0031349	59	0.193
response to extracellular stimulus	GO:0009991	116	0.192
organonitrogen compound metabolic process	GO:1901564	318	0.192
death	GO:0016265	284	0.189
regulation of phosphorylation	GO:0042325	147	0.188
response to oxygen containing compound	GO:1901700	200	0.185
positive regulation of immune system process	GO:0002684	68	0.180
defense response to other organism	GO:0098542	225	0.177
organic substance transport	GO:0071702	257	0.177
regulation of multi organism process	GO:0043900	131	0.176
positive regulation of response to stimulus	GO:0048584	323	0.174
dorsal ventral pattern formation	GO:0009953	133	0.174
protein localization to organelle	GO:0033365	82	0.172
cell death	GO:0008219	279	0.172
response to superoxide	GO:0000303	3	0.172
response to hexose	GO:0009746	3	0.170
positive regulation of rna biosynthetic process	GO:1902680	266	0.169
protein import into nucleus	GO:0006606	51	0.166
phosphorylation	GO:0016310	294	0.163
regulation of dna metabolic process	GO:0051052	34	0.163
response to monosaccharide	GO:0034284	4	0.162
cell motility	GO:0048870	251	0.160
positive regulation of cell size	GO:0045793	21	0.158
developmental programmed cell death	GO:0010623	138	0.152
melanin metabolic process	GO:0006582	47	0.150
protein transport	GO:0015031	155	0.148
positive regulation of cell communication	GO:0010647	250	0.148
cation homeostasis	GO:0055080	51	0.147
regulation of molecular function	GO:0065009	217	0.144
organic hydroxy compound metabolic process	GO:1901615	83	0.144
nucleocytoplasmic transport	GO:0006913	72	0.144
regulation of protein metabolic process	GO:0051246	256	0.143
positive regulation of cellular component organization	GO:0051130	156	0.143
positive regulation of immune effector process	GO:0002699	28	0.143
nitrogen compound transport	GO:0071705	85	0.141
response to nutrient levels	GO:0031667	114	0.141
mapk cascade	GO:0000165	107	0.139
negative regulation of signaling	GO:0023057	219	0.138
programmed cell death	GO:0012501	257	0.137
positive regulation of cellular catabolic process	GO:0031331	95	0.136
defense response to fungus	GO:0050832	48	0.135
chemical homeostasis	GO:0048878	92	0.135
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.135
neurological system process	GO:0050877	358	0.134
muscle cell differentiation	GO:0042692	103	0.134
positive regulation of gene expression	GO:0010628	290	0.134
cellular lipid metabolic process	GO:0044255	83	0.133
gland development	GO:0048732	191	0.131
organic acid metabolic process	GO:0006082	103	0.126
regulation of anatomical structure size	GO:0090066	163	0.125
regulation of innate immune response	GO:0045088	71	0.125
imaginal disc derived wing morphogenesis	GO:0007476	337	0.125
regulation of cellular response to stress	GO:0080135	89	0.123
heart development	GO:0007507	82	0.122
regulation of cellular component size	GO:0032535	98	0.121
regulation of programmed cell death	GO:0043067	152	0.120
stress activated mapk cascade	GO:0051403	52	0.120
columnar cuboidal epithelial cell development	GO:0002066	249	0.119
antibacterial peptide production	GO:0002778	22	0.118
lipid homeostasis	GO:0055088	33	0.118
regulation of defense response	GO:0031347	102	0.117
chromatin organization	GO:0006325	207	0.116
negative regulation of cell differentiation	GO:0045596	143	0.116
positive regulation of phosphorus metabolic process	GO:0010562	139	0.115
chromatin modification	GO:0016568	147	0.114
regulation of terminal button organization	GO:2000331	11	0.114
locomotory behavior	GO:0007626	176	0.113
cellular response to lipopolysaccharide	GO:0071222	3	0.112
ion transport	GO:0006811	145	0.111
immune response regulating signaling pathway	GO:0002764	2	0.111
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.111
transcription from rna polymerase ii promoter	GO:0006366	368	0.111
digestive system development	GO:0055123	149	0.110
regulation of phosphate metabolic process	GO:0019220	210	0.108
regulation of defense response to bacterium	GO:1900424	30	0.108
intracellular transport	GO:0046907	228	0.107
cuticle pigmentation	GO:0048067	22	0.107
epithelial cell differentiation	GO:0030855	322	0.107
cell migration	GO:0016477	238	0.106
regulation of transport	GO:0051049	181	0.106
response to external biotic stimulus	GO:0043207	293	0.103
appendage morphogenesis	GO:0035107	397	0.102
eggshell formation	GO:0030703	105	0.101
cellular response to reactive oxygen species	GO:0034614	14	0.101
cellular response to organic cyclic compound	GO:0071407	32	0.100
response to other organism	GO:0051707	293	0.097
cellular response to chemical stimulus	GO:0070887	199	0.097
salivary gland development	GO:0007431	162	0.097
muscle structure development	GO:0061061	224	0.097
regulation of localization	GO:0032879	275	0.097
regulation of cuticle pigmentation	GO:0048079	16	0.096
positive regulation of catabolic process	GO:0009896	105	0.096
oxoacid metabolic process	GO:0043436	103	0.095
secretion	GO:0046903	109	0.095
protein phosphorylation	GO:0006468	169	0.093
male mating behavior	GO:0060179	70	0.093
spindle organization	GO:0007051	253	0.092
cell division	GO:0051301	248	0.091
cuticle development	GO:0042335	86	0.091
forebrain development	GO:0030900	2	0.091
regulation of defense response to virus by host	GO:0050691	10	0.091
regulation of chromosome organization	GO:0033044	64	0.090
negative regulation of growth	GO:0045926	84	0.090
regulation of gene expression epigenetic	GO:0040029	128	0.088
defense response to gram negative bacterium	GO:0050829	94	0.087
imaginal disc derived appendage development	GO:0048737	399	0.086
regulation of catabolic process	GO:0009894	170	0.086
regulation of cellular amine metabolic process	GO:0033238	3	0.083
dorsal closure	GO:0007391	79	0.083
defense response to bacterium	GO:0042742	178	0.083
digestive tract morphogenesis	GO:0048546	127	0.082
regulation of cell cycle process	GO:0010564	181	0.082
negative regulation of programmed cell death	GO:0043069	72	0.080
response to nitrogen compound	GO:1901698	90	0.080
autophagy	GO:0006914	108	0.080
regulation of intracellular transport	GO:0032386	64	0.079
purine nucleotide catabolic process	GO:0006195	109	0.079
protein targeting to nucleus	GO:0044744	51	0.079
muscle cell development	GO:0055001	50	0.079
chromosome organization	GO:0051276	360	0.078
mitotic spindle organization	GO:0007052	220	0.078
tube development	GO:0035295	244	0.078
antimicrobial humoral response	GO:0019730	99	0.077
border follicle cell migration	GO:0007298	113	0.076
muscle organ development	GO:0007517	127	0.076
regulation of developmental pigmentation	GO:0048070	24	0.075
tor signaling	GO:0031929	32	0.075
secondary metabolic process	GO:0019748	75	0.073
cellular protein localization	GO:0034613	160	0.071
antibacterial humoral response	GO:0019731	44	0.071
peptidyl amino acid modification	GO:0018193	105	0.071
cellular response to starvation	GO:0009267	61	0.071
response to wounding	GO:0009611	94	0.069
determination of adult lifespan	GO:0008340	137	0.069
carbohydrate metabolic process	GO:0005975	82	0.069
cellular response to organic substance	GO:0071310	132	0.069
negative regulation of intracellular signal transduction	GO:1902532	57	0.069
regulation of cellular protein metabolic process	GO:0032268	243	0.068
metal ion homeostasis	GO:0055065	44	0.068
response to ionizing radiation	GO:0010212	32	0.068
cellular protein modification process	GO:0006464	438	0.068
cellular amino acid metabolic process	GO:0006520	61	0.068
response to carbohydrate	GO:0009743	15	0.067
cellular macromolecule localization	GO:0070727	220	0.066
skeletal muscle fiber development	GO:0048741	3	0.066
ion homeostasis	GO:0050801	55	0.066
antimicrobial peptide production	GO:0002775	46	0.065
heart morphogenesis	GO:0003007	32	0.064
taxis	GO:0042330	304	0.064
dendrite development	GO:0016358	204	0.064
regulation of cell differentiation	GO:0045595	302	0.063
connective tissue development	GO:0061448	3	0.063
vesicle mediated transport	GO:0016192	381	0.063
regulation of blood circulation	GO:1903522	21	0.062
positive regulation of cell death	GO:0010942	69	0.062
response to temperature stimulus	GO:0009266	106	0.062
regulation of multicellular organism growth	GO:0040014	40	0.062
nuclear transport	GO:0051169	72	0.061
chromatin silencing	GO:0006342	76	0.061
regulation of jun kinase activity	GO:0043506	8	0.060	Human Mouse
regulation of cellular catabolic process	GO:0031329	157	0.060
cellular ketone metabolic process	GO:0042180	24	0.060
negative regulation of nervous system development	GO:0051961	92	0.059
response to virus	GO:0009615	28	0.059
cellular response to carbohydrate stimulus	GO:0071322	4	0.059
exocrine system development	GO:0035272	162	0.059
response to inorganic substance	GO:0010035	44	0.059
regulation of biosynthetic process of antibacterial peptides active against gram positive bacteria	GO:0002816	3	0.059
protein localization to nucleus	GO:0034504	55	0.058
single organism intracellular transport	GO:1902582	207	0.058
regulation of cellular component biogenesis	GO:0044087	201	0.058
cation transmembrane transport	GO:0098655	88	0.058
associative learning	GO:0008306	65	0.058
carboxylic acid metabolic process	GO:0019752	92	0.057
salivary gland morphogenesis	GO:0007435	145	0.057
cognition	GO:0050890	141	0.057
negative regulation of signal transduction	GO:0009968	206	0.055
tissue death	GO:0016271	102	0.055
regulation of intracellular protein transport	GO:0033157	46	0.054
sprouting of injured axon	GO:0048682	3	0.054
signal transduction by phosphorylation	GO:0023014	107	0.053
apoptotic process	GO:0006915	159	0.053
adenylate cyclase modulating g protein coupled receptor signaling pathway	GO:0007188	17	0.053
cytoplasmic transport	GO:0016482	130	0.053
regulation of transferase activity	GO:0051338	58	0.053
positive regulation of organelle organization	GO:0010638	65	0.053
organophosphate metabolic process	GO:0019637	195	0.052
single organism biosynthetic process	GO:0044711	206	0.052
positive regulation of transcription dna templated	GO:0045893	266	0.052
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.052
molting cycle	GO:0042303	56	0.052
cell proliferation	GO:0008283	299	0.052
positive regulation of rna metabolic process	GO:0051254	271	0.051
regulation of nucleocytoplasmic transport	GO:0046822	35	0.051
positive regulation of molecular function	GO:0044093	136	0.051
positive regulation of phosphate metabolic process	GO:0045937	139	0.051
regulation of myoblast fusion	GO:1901739	6	0.050
positive regulation of defense response to virus by host	GO:0002230	10	0.049
axon regeneration	GO:0031103	8	0.049
catabolic process	GO:0009056	409	0.049
wound healing	GO:0042060	75	0.049
single organism cellular localization	GO:1902580	180	0.049
nuclear body organization	GO:0030575	6	0.049
response to decreased oxygen levels	GO:0036293	58	0.048
myoblast fusion	GO:0007520	43	0.048
regulation of apoptotic process	GO:0042981	130	0.048
regulation of antimicrobial humoral response	GO:0002759	50	0.048
pigmentation	GO:0043473	75	0.048
regulation of protein import into nucleus	GO:0042306	28	0.048
endomembrane system organization	GO:0010256	119	0.047
regulation of cellular localization	GO:0060341	136	0.047
nuclear import	GO:0051170	51	0.046
sensory perception	GO:0007600	196	0.046
myotube differentiation	GO:0014902	46	0.046
cation transport	GO:0006812	110	0.046
regulation of protein modification process	GO:0031399	112	0.046
response to fungus	GO:0009620	50	0.046
response to organonitrogen compound	GO:0010243	75	0.045
defense response to virus	GO:0051607	23	0.045
cellular response to oxidative stress	GO:0034599	28	0.045
multi multicellular organism process	GO:0044706	123	0.045
positive regulation of programmed cell death	GO:0043068	62	0.045
head development	GO:0060322	135	0.045
negative regulation of apoptotic process	GO:0043066	63	0.044
regulation of cell size	GO:0008361	63	0.044
regulation of humoral immune response	GO:0002920	51	0.044
male gamete generation	GO:0048232	201	0.044
response to metal ion	GO:0010038	23	0.043
response to alcohol	GO:0097305	95	0.043
circulatory system development	GO:0072359	82	0.043
gland morphogenesis	GO:0022612	145	0.043
post embryonic appendage morphogenesis	GO:0035120	385	0.042
positive regulation of reactive oxygen species metabolic process	GO:2000379	0	0.042
regulation of epithelial cell differentiation	GO:0030856	4	0.042
protein targeting	GO:0006605	64	0.041
regulation of chromatin modification	GO:1903308	28	0.041
nucleobase containing compound catabolic process	GO:0034655	165	0.041
negative regulation of protein metabolic process	GO:0051248	85	0.041
striated muscle cell differentiation	GO:0051146	90	0.041
neuron projection guidance	GO:0097485	241	0.041
activation of innate immune response	GO:0002218	4	0.040
regulation of tor signaling	GO:0032006	21	0.040
muscle tissue development	GO:0060537	30	0.040
negative regulation of immune response	GO:0050777	39	0.040
ameboidal type cell migration	GO:0001667	151	0.040
positive regulation of cysteine type endopeptidase activity involved in apoptotic process	GO:0043280	23	0.039
sterol homeostasis	GO:0055092	4	0.039
inorganic ion transmembrane transport	GO:0098660	73	0.039
lipopolysaccharide mediated signaling pathway	GO:0031663	1	0.039
organ or tissue specific immune response	GO:0002251	10	0.039
somatic muscle development	GO:0007525	66	0.039
endocytosis	GO:0006897	310	0.039
single organism catabolic process	GO:0044712	228	0.038
embryo development ending in birth or egg hatching	GO:0009792	152	0.038
response to purine containing compound	GO:0014074	12	0.038
phenol containing compound metabolic process	GO:0018958	57	0.038
cellular calcium ion homeostasis	GO:0006874	21	0.038
organonitrogen compound biosynthetic process	GO:1901566	117	0.037
response to hydrogen peroxide	GO:0042542	11	0.037
negative regulation of cell proliferation	GO:0008285	69	0.037
tissue morphogenesis	GO:0048729	297	0.037
epithelial cell development	GO:0002064	274	0.037
metal ion transport	GO:0030001	74	0.037
protein complex assembly	GO:0006461	200	0.037
negative regulation of immune system process	GO:0002683	50	0.037
defense response	GO:0006952	300	0.037
regulation of antibacterial peptide biosynthetic process	GO:0002808	22	0.037
striated muscle cell development	GO:0055002	50	0.037
response to lipopolysaccharide	GO:0032496	4	0.036
regulation of establishment of protein localization	GO:0070201	61	0.036
regulation of catalytic activity	GO:0050790	185	0.036
negative regulation of cell death	GO:0060548	81	0.036
cellular response to oxygen containing compound	GO:1901701	79	0.036
positive regulation of protein modification process	GO:0031401	58	0.036
acylglycerol metabolic process	GO:0006639	12	0.036
multicellular organismal homeostasis	GO:0048871	41	0.036
appendage development	GO:0048736	401	0.036
negative regulation of purine nucleotide biosynthetic process	GO:1900372	3	0.036
regulation of multicellular organismal development	GO:2000026	414	0.035
protein localization	GO:0008104	284	0.035
signal release	GO:0023061	49	0.035
ion transmembrane transport	GO:0034220	122	0.035
anterior midgut ectodermal morphogenesis	GO:0007441	4	0.035
axon development	GO:0061564	297	0.035
peptide biosynthetic process	GO:0043043	42	0.035
response to hypoxia	GO:0001666	53	0.034
single organism carbohydrate metabolic process	GO:0044723	72	0.034
pigment metabolic process	GO:0042440	84	0.034
cellular response to ionizing radiation	GO:0071479	15	0.034
salivary gland histolysis	GO:0035070	88	0.034
humoral immune response	GO:0006959	117	0.034
regulation of stress activated mapk cascade	GO:0032872	41	0.034
cellular response to abiotic stimulus	GO:0071214	58	0.033
heart contraction	GO:0060047	26	0.033
regulation of biosynthetic process of antibacterial peptides active against gram negative bacteria	GO:0002813	14	0.033
regulation of protein kinase activity	GO:0045859	51	0.033
regulation of cellular ketone metabolic process	GO:0010565	3	0.033
cellular divalent inorganic cation homeostasis	GO:0072503	23	0.033
positive regulation of multicellular organismal process	GO:0051240	143	0.033
syncytium formation	GO:0006949	43	0.033
positive regulation of purine nucleotide metabolic process	GO:1900544	55	0.032
response to endoplasmic reticulum stress	GO:0034976	28	0.032
hydrogen peroxide metabolic process	GO:0042743	6	0.032
tissue migration	GO:0090130	155	0.032
positive regulation of phosphorylation	GO:0042327	87	0.032
micropyle formation	GO:0046844	4	0.032
response to oxygen levels	GO:0070482	59	0.032
epithelium migration	GO:0090132	148	0.032
regulation of system process	GO:0044057	36	0.032
regulation of autophagy	GO:0010506	62	0.031
single organism nuclear import	GO:1902593	51	0.031
positive regulation of antibacterial peptide production	GO:0002803	20	0.031
response to biotic stimulus	GO:0009607	294	0.031
peptide metabolic process	GO:0006518	80	0.031
stem cell differentiation	GO:0048863	117	0.031
ovarian follicle cell migration	GO:0007297	121	0.031
antibacterial peptide biosynthetic process	GO:0002780	22	0.031
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.031
adult behavior	GO:0030534	137	0.031
spindle assembly involved in mitosis	GO:0090307	50	0.031
regulation of cell cycle	GO:0051726	291	0.030
calcium ion transport	GO:0006816	24	0.030
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.030
negative regulation of cell development	GO:0010721	62	0.030
regulation of synaptic transmission	GO:0050804	69	0.030
autophagic cell death	GO:0048102	83	0.030
cellular response to hormone stimulus	GO:0032870	44	0.030
regulation of chromatin organization	GO:1902275	32	0.030
syncytium formation by plasma membrane fusion	GO:0000768	43	0.030
stem cell proliferation	GO:0072089	88	0.029
organic substance catabolic process	GO:1901575	308	0.029
cellular response to arsenic containing substance	GO:0071243	6	0.029
defense response to gram positive bacterium	GO:0050830	41	0.029
epidermal cell differentiation	GO:0009913	51	0.029
imaginal disc pattern formation	GO:0007447	91	0.029
positive regulation of response to biotic stimulus	GO:0002833	31	0.029
positive regulation of antibacterial peptide biosynthetic process	GO:0006963	20	0.029
divalent inorganic cation homeostasis	GO:0072507	29	0.029
cell growth	GO:0016049	108	0.029
lipid biosynthetic process	GO:0008610	46	0.029
spermatogenesis	GO:0007283	200	0.029
endoplasmic reticulum organization	GO:0007029	13	0.029
cellular cation homeostasis	GO:0030003	38	0.028
ribose phosphate metabolic process	GO:0019693	145	0.028
negative regulation of cellular response to oxidative stress	GO:1900408	1	0.028
negative regulation of gene expression epigenetic	GO:0045814	77	0.028
secretion by cell	GO:0032940	101	0.028
positive regulation of intracellular transport	GO:0032388	42	0.028
axonogenesis	GO:0007409	290	0.028
response to organophosphorus	GO:0046683	2	0.028
skeletal muscle organ development	GO:0060538	48	0.027
negative regulation of cellular protein metabolic process	GO:0032269	85	0.027
regulation of response to external stimulus	GO:0032101	115	0.026
spermatid differentiation	GO:0048515	114	0.026
histolysis	GO:0007559	102	0.026
regulation of heart contraction	GO:0008016	21	0.026
positive regulation of intracellular signal transduction	GO:1902533	116	0.026
positive regulation of protein phosphorylation	GO:0001934	34	0.026
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.026
positive regulation of protein transport	GO:0051222	37	0.025
purine nucleotide metabolic process	GO:0006163	146	0.025
posttranscriptional regulation of gene expression	GO:0010608	145	0.025
response to uv	GO:0009411	24	0.025	Human
negative regulation of wnt signaling pathway	GO:0030178	28	0.025
growth	GO:0040007	359	0.025
tube morphogenesis	GO:0035239	191	0.025
molting cycle process	GO:0022404	29	0.025
establishment of protein localization	GO:0045184	163	0.025
terminal button organization	GO:0072553	19	0.025
vesicle organization	GO:0016050	44	0.025
olfactory behavior	GO:0042048	97	0.025
regulation of cellular amino acid metabolic process	GO:0006521	0	0.025
response to radiation	GO:0009314	155	0.024	Human
negative regulation of neurogenesis	GO:0050768	53	0.024
intracellular protein transport	GO:0006886	104	0.024
central nervous system development	GO:0007417	201	0.024
cellular response to nutrient levels	GO:0031669	62	0.024
protein complex biogenesis	GO:0070271	201	0.024
carbohydrate homeostasis	GO:0033500	12	0.024
brain development	GO:0007420	120	0.024
myotube cell development	GO:0014904	3	0.024
regulation of anatomical structure morphogenesis	GO:0022603	242	0.024
regulation of neural precursor cell proliferation	GO:2000177	35	0.024
regulation of mapk cascade	GO:0043408	92	0.023
zymogen activation	GO:0031638	20	0.023
activation of cysteine type endopeptidase activity	GO:0097202	17	0.023
regulation of i kappab kinase nf kappab signaling	GO:0043122	2	0.023
regulation of defense response to virus	GO:0050688	14	0.023
anatomical structure homeostasis	GO:0060249	97	0.023
positive regulation of cysteine type endopeptidase activity	GO:2001056	24	0.023
negative regulation of response to oxidative stress	GO:1902883	1	0.023
response to lipid	GO:0033993	38	0.023
tissue homeostasis	GO:0001894	36	0.023
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.023
regulation of protein localization	GO:0032880	76	0.023
lateral inhibition	GO:0046331	206	0.023
regulation of dna templated transcription in response to stress	GO:0043620	4	0.023
actin filament organization	GO:0007015	126	0.023
neutral lipid metabolic process	GO:0006638	12	0.022
regulation of antibacterial peptide production	GO:0002786	22	0.022
response to bacterium	GO:0009617	198	0.022
multi organism reproductive behavior	GO:0044705	121	0.022
regulation of jnk cascade	GO:0046328	40	0.022
positive regulation of ras gtpase activity	GO:0032320	36	0.022
cellular response to biotic stimulus	GO:0071216	4	0.022
wing disc pattern formation	GO:0035222	66	0.021
ribonucleoside catabolic process	GO:0042454	112	0.021
regulation of growth	GO:0040008	233	0.021
neuron projection regeneration	GO:0031102	8	0.021

Mekk1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.052

Loading network...

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network