Drosophila melanogaster

97 known processes

HDAC6 (Dmel_CG6170)

CG6170 gene product from transcript CG6170-RA

(Aliases: dmHDA404,HDAC2,dHDAC6,dHDAC2,DHDAC2,DmHDAC2,Dmel\CG6170,HDAC,CG6170)

HDAC6 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
synaptic vesicle endocytosisGO:0048488280.694
synaptic transmissionGO:00072682880.519
synaptic vesicle transportGO:0048489500.466
signal releaseGO:0023061490.361
catabolic processGO:00090564090.339
Human
establishment of vesicle localizationGO:0051650510.321
establishment of synaptic vesicle localizationGO:0097480500.287
vesicle localizationGO:0051648550.271
neuromuscular synaptic transmissionGO:0007274670.258
single organism cellular localizationGO:19025801800.249
synaptic vesicle recyclingGO:0036465280.236
organelle localizationGO:00516401480.223
Human
cellular catabolic processGO:00442483720.214
Human
synaptic vesicle exocytosisGO:0016079160.209
single organism membrane organizationGO:0044802930.178
establishment of organelle localizationGO:00516561220.177
organic substance catabolic processGO:19015753080.170
Human
synaptic vesicle localizationGO:0097479530.157
nitrogen compound transportGO:0071705850.139
establishment of localization in cellGO:00516494020.137
single organism membrane fusionGO:0044801420.132
regulation of secretion by cellGO:1903530390.129
positive regulation of cell communicationGO:00106472500.124
Human
positive regulation of secretionGO:0051047220.121
autophagyGO:00069141080.116
Human
regulation of cellular localizationGO:00603411360.114
synapse organizationGO:00508081960.113
single organism catabolic processGO:00447122280.111
Human
regulation of secretionGO:0051046440.107
secretionGO:00469031090.101
neuron neuron synaptic transmissionGO:0007270140.098
protein complex biogenesisGO:00702712010.097
Human
vesicle fusionGO:0006906190.097
lipid modificationGO:0030258240.084
secretion by cellGO:00329401010.082
cellular nitrogen compound catabolic processGO:00442701650.081
organelle fissionGO:00482853400.078
membrane organizationGO:00610241120.077
regulation of intracellular signal transductionGO:19025312360.075
protein modification processGO:00362114380.072
ion transportGO:00068111450.072
organonitrogen compound metabolic processGO:19015643180.071
positive regulation of exocytosisGO:004592140.070
neurotransmitter transportGO:0006836370.067
regulation of multi organism processGO:00439001310.066
axon developmentGO:00615642970.063
aromatic compound catabolic processGO:00194391660.061
macromolecular complex assemblyGO:00650032560.060
Human
regulation of transportGO:00510491810.060
single organism behaviorGO:00447083910.059
vesicle organizationGO:0016050440.059
polyol biosynthetic processGO:004617330.058
intracellular transportGO:00469072280.058
Human
imaginal disc derived appendage developmentGO:00487373990.058
vesicle mediated transportGO:00161923810.057
positive regulation of cell migrationGO:003033520.057
Human
small molecule metabolic processGO:00442813050.056
synapse assemblyGO:00074161430.055
positive regulation of gene expressionGO:00106282900.055
intracellular signal transductionGO:00355563000.055
cell deathGO:00082192790.054
Human
regulation of hormone levelsGO:0010817400.054
positive regulation of secretion by cellGO:1903532200.052
organic cyclic compound catabolic processGO:19013611680.049
oxidation reduction processGO:00551141230.049
positive regulation of signalingGO:00230562430.048
Human
carbohydrate derivative metabolic processGO:19011352170.047
lipid metabolic processGO:00066291210.047
regulation of neurotransmitter levelsGO:0001505380.046
regulation of reproductive processGO:2000241540.046
homeostatic processGO:00425921990.046
membrane fusionGO:0061025420.045
organonitrogen compound catabolic processGO:19015651280.045
oocyte differentiationGO:00099941450.044
ribonucleoside metabolic processGO:00091191270.044
organelle fusionGO:0048284460.044
positive regulation of transportGO:0051050920.044
heterocycle catabolic processGO:00467001660.043
regulation of localizationGO:00328792750.043
Human
intracellular protein transportGO:00068861040.043
Human
axonogenesisGO:00074092900.042
nucleobase containing compound catabolic processGO:00346551650.042
epithelial cell developmentGO:00020642740.040
axon guidanceGO:00074112330.040
nucleoside metabolic processGO:00091161270.039
organic substance transportGO:00717022570.039
Human
negative regulation of response to stimulusGO:00485852580.039
cellular lipid metabolic processGO:0044255830.039
response to hormoneGO:0009725450.039
Rat
carbohydrate derivative catabolic processGO:19011361180.038
response to organic substanceGO:00100332840.038
Human Rat
maintenance of presynaptic active zone structureGO:004879080.038
response to endogenous stimulusGO:00097191190.038
Rat
endocytosisGO:00068973100.038
purine containing compound catabolic processGO:00725231120.037
phosphatidylinositol phosphorylationGO:0046854100.037
cellular macromolecule localizationGO:00707272200.037
Human
nucleotide metabolic processGO:00091171610.037
establishment of protein localization to plasma membraneGO:009000290.037
organophosphate metabolic processGO:00196371950.036
response to glucoseGO:000974920.036
regulation of cellular component biogenesisGO:00440872010.036
Human
inter male aggressive behaviorGO:0002121600.035
protein complex assemblyGO:00064612000.035
Human
cell maturationGO:00484691440.034
regulation of vesicle mediated transportGO:0060627590.034
forebrain developmentGO:003090020.034
microtubule based transportGO:0010970420.034
regulation of behaviorGO:0050795750.034
regulation of multicellular organismal developmentGO:20000264140.034
developmental programmed cell deathGO:00106231380.033
neuron projection guidanceGO:00974852410.033
ribonucleoside catabolic processGO:00424541120.033
response to monosaccharideGO:003428440.033
organic hydroxy compound metabolic processGO:1901615830.033
hindbrain developmentGO:003090220.033
positive regulation of nucleobase containing compound metabolic processGO:00459353320.032
cellular protein modification processGO:00064644380.032
regulation of cell developmentGO:00602842150.032
regulation of peptide secretionGO:000279160.032
regulation of synaptic growth at neuromuscular junctionGO:0008582890.032
positive regulation of transcription dna templatedGO:00458932660.032
regulation of synaptic transmissionGO:0050804690.031
developmental maturationGO:00217001720.031
carboxylic acid transportGO:0046942180.031
imaginal disc derived wing morphogenesisGO:00074763370.031
cellular response to hexose stimulusGO:007133110.031
regulation of excitatory postsynaptic membrane potentialGO:006007930.031
single organism intracellular transportGO:19025822070.031
Human
exocytosisGO:0006887280.030
regulation of synapse organizationGO:00508071100.029
oxoacid metabolic processGO:00434361030.029
epithelial cell differentiationGO:00308553220.029
axon cargo transportGO:0008088290.029
gtp catabolic processGO:0006184720.029
cell cell signaling involved in cell fate commitmentGO:00451682100.029
purine ribonucleoside metabolic processGO:00461281270.028
cellular macromolecule catabolic processGO:00442651360.028
Human
response to hexoseGO:000974630.028
regulation of immune system processGO:00026821760.027
response to acid chemicalGO:0001101250.027
locomotory behaviorGO:00076261760.026
feeding behaviorGO:0007631500.026
imaginal disc derived appendage morphogenesisGO:00351143950.026
actin filament organizationGO:00070151260.026
nucleoside triphosphate metabolic processGO:00091411200.025
regulation of transcription from rna polymerase ii promoterGO:00063573780.025
Human
neurotransmitter secretionGO:0007269350.025
cellular response to monosaccharide stimulusGO:007132620.025
phosphorylationGO:00163102940.025
organic acid metabolic processGO:00060821030.025
purine ribonucleoside catabolic processGO:00461301120.025
compound eye developmentGO:00487493070.025
carboxylic acid metabolic processGO:0019752920.024
adult locomotory behaviorGO:0008344760.024
nucleoside catabolic processGO:00091641120.024
negative regulation of cellular biosynthetic processGO:00313272770.024
Human
organic hydroxy compound biosynthetic processGO:1901617210.024
response to lipidGO:0033993380.024
Rat
positive regulation of cell motilityGO:200014730.024
Human
positive regulation of signal transductionGO:00099672230.024
Human
energy derivation by oxidation of organic compoundsGO:0015980320.023
regulation of catabolic processGO:00098941700.023
l glutamate importGO:005193810.023
positive regulation of response to stimulusGO:00485843230.023
Human
regulation of membrane potentialGO:0042391350.023
response to temperature stimulusGO:00092661060.023
positive regulation of macromolecule biosynthetic processGO:00105572830.023
Human
protein localization to plasma membraneGO:0072659130.023
growthGO:00400073590.022
monocarboxylic acid transportGO:001571830.022
regulation of synaptic vesicle exocytosisGO:200030030.022
appendage developmentGO:00487364010.022
neuromuscular junction developmentGO:00075281490.022
regulation of cellular catabolic processGO:00313291570.022
purine nucleoside metabolic processGO:00422781270.022
central nervous system developmentGO:00074172010.022
Rat
negative regulation of calcium ion importGO:009028120.021
response to ketoneGO:1901654340.021
Rat
response to abiotic stimulusGO:00096283410.021
mitotic nuclear divisionGO:00070672130.021
blastoderm segmentationGO:00073501590.021
response to painGO:004826530.021
response to oxygen containing compoundGO:19017002000.021
Human Rat
learning or memoryGO:00076111410.021
appendage morphogenesisGO:00351073970.020
response to nitrogen compoundGO:1901698900.020
regulation of insulin secretionGO:005079650.020
positive regulation of rna biosynthetic processGO:19026802660.020
glycosyl compound metabolic processGO:19016571270.020
generation of precursor metabolites and energyGO:0006091420.020
cognitionGO:00508901410.020
negative regulation of cell communicationGO:00106482230.020
response to reactive oxygen speciesGO:0000302240.020
Human
endomembrane system organizationGO:00102561190.020
eye developmentGO:00016543230.020
lateral inhibitionGO:00463312060.020
mrna metabolic processGO:00160711240.019
positive regulation of biosynthetic processGO:00098913160.019
Human
morphogenesis of an epitheliumGO:00020092760.019
regulation of growthGO:00400082330.019
transmembrane transportGO:00550851390.019
cell migrationGO:00164772380.019
Human
amine metabolic processGO:0009308120.019
regulation of synapse structure and activityGO:00508031280.019
regulation of synaptic vesicle transportGO:1902803100.019
macromolecule catabolic processGO:00090571610.019
Human
wing disc morphogenesisGO:00074723440.019
cellular response to carbohydrate stimulusGO:007132240.019
regulation of exocytosisGO:001715760.019
positive regulation of intracellular signal transductionGO:19025331160.019
segmentationGO:00352822070.019
nucleobase containing small molecule metabolic processGO:00550861740.019
sulfur compound metabolic processGO:0006790590.018
protein transportGO:00150311550.018
Human
negative regulation of multicellular organismal processGO:00512411420.018
stress activated mapk cascadeGO:0051403520.018
negative regulation of insulin secretionGO:004667610.018
purine nucleoside triphosphate metabolic processGO:00091441190.018
cellular response to organic substanceGO:00713101320.018
Human Rat
hyperosmotic salinity responseGO:004253810.018
chemotaxisGO:00069352490.018
cellular protein complex assemblyGO:0043623710.017
Human
positive regulation of synaptic transmissionGO:0050806150.017
organophosphate catabolic processGO:00464341120.017
cellular macromolecular complex assemblyGO:00346221530.017
Human
anatomical structure homeostasisGO:0060249970.017
oocyte anterior posterior axis specificationGO:0007314720.017
regulation of steroid metabolic processGO:001921820.017
detection of stimulus involved in sensory perceptionGO:0050906920.017
response to organic cyclic compoundGO:0014070890.017
Rat
neurological system processGO:00508773580.017
ribonucleoside triphosphate metabolic processGO:00091991190.017
positive regulation of nitrogen compound metabolic processGO:00511733540.017
nuclear divisionGO:00002803320.017
sensory perception of painGO:001923340.017
hormone secretionGO:004687970.016
cellular carbohydrate metabolic processGO:0044262220.016
ribonucleoside triphosphate catabolic processGO:00092031080.016
columnar cuboidal epithelial cell developmentGO:00020662490.016
establishment or maintenance of cell polarityGO:00071631670.016
oocyte developmentGO:00485991240.016
dna packagingGO:0006323910.016
cellular response to starvationGO:0009267610.016
Human
alcohol biosynthetic processGO:0046165140.016
glycosyl compound catabolic processGO:19016581120.016
purine nucleoside catabolic processGO:00061521120.016
positive regulation of cellular biosynthetic processGO:00313283160.016
positive regulation of nucleic acid templated transcriptionGO:19035082660.016
plasma membrane organizationGO:0007009260.016
embryonic pattern specificationGO:00098801740.016
negative regulation of gene expressionGO:00106293870.016
Human
sensory perception of chemical stimulusGO:00076061160.016
organonitrogen compound biosynthetic processGO:19015661170.016
protein phosphorylationGO:00064681690.016
organic anion transportGO:0015711280.016
response to inorganic substanceGO:0010035440.015
Human
multi organism reproductive behaviorGO:00447051210.015
phagocytosisGO:00069092150.015
associative learningGO:0008306650.015
regulation of system processGO:0044057360.015
synaptic transmission glutamatergicGO:003524970.015
purine ribonucleotide metabolic processGO:00091501450.015
regulation of cell substrate adhesionGO:001081020.015
negative regulation of peptide secretionGO:000279210.015
steroid biosynthetic processGO:0006694160.015
defense response to gram negative bacteriumGO:0050829940.015
germarium derived egg chamber formationGO:00072931010.015
regulation of cell cycleGO:00517262910.015
ovarian follicle cell developmentGO:00307072480.015
regulation of autophagyGO:0010506620.015
proteolysisGO:00065081920.015
Human
immune system processGO:00023763470.015
carbohydrate metabolic processGO:0005975820.015
ameboidal type cell migrationGO:00016671510.015
Human
phenol containing compound metabolic processGO:0018958570.015
cellular ketone metabolic processGO:0042180240.015
stress activated protein kinase signaling cascadeGO:0031098550.015
pyridine containing compound metabolic processGO:007252430.015
transcription from rna polymerase ii promoterGO:00063663680.015
Human
response to mechanical stimulusGO:0009612280.014
gland developmentGO:00487321910.014
meiotic nuclear divisionGO:00071261510.014
kidney developmentGO:000182230.014
ribonucleotide metabolic processGO:00092591450.014
organic acid transportGO:0015849180.014
heart processGO:0003015370.014
monocarboxylic acid metabolic processGO:0032787290.014
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.014
positive regulation of cellular catabolic processGO:0031331950.014
defense responseGO:00069523000.014
single organism carbohydrate metabolic processGO:0044723720.014
negative regulation of nitrogen compound metabolic processGO:00511722650.014
Human
microtubule based movementGO:0007018510.014
protein localization to membraneGO:0072657190.014
positive regulation of catabolic processGO:00098961050.014
cytoplasmic transportGO:00164821300.014
response to lipopolysaccharideGO:003249640.014
purine containing compound metabolic processGO:00725211550.013
negative regulation of biosynthetic processGO:00098902770.013
Human
positive regulation of macromolecule metabolic processGO:00106044050.013
Human
negative regulation of nucleobase containing compound metabolic processGO:00459342610.013
Human
anion transportGO:0006820410.013
single organism biosynthetic processGO:00447112060.013
cellular response to mechanical stimulusGO:007126020.013
response to organonitrogen compoundGO:0010243750.013
negative regulation of programmed cell deathGO:0043069720.013
body morphogenesisGO:001017120.013
positive regulation of rna metabolic processGO:00512542710.013
regulation of response to stressGO:00801342000.013
Human
developmental growthGO:00485892800.013
deathGO:00162652840.013
Human
regulation of cellular ketone metabolic processGO:001056530.013
negative regulation of phosphatidylinositol 3 kinase signalingGO:001406740.013
regulation of peptide hormone secretionGO:009027650.013
purine nucleotide catabolic processGO:00061951090.013
tube morphogenesisGO:00352391910.012
synaptic vesicle fusion to presynaptic membraneGO:003162970.012
regulation of cellular amine metabolic processGO:003323830.012
negative regulation of signal transductionGO:00099682060.012
regionalizationGO:00030024160.012
mitotic cell cycle phase transitionGO:00447721380.012
detection of chemical stimulus involved in sensory perceptionGO:0050907750.012
cellular response to endogenous stimulusGO:0071495800.012
Rat
spindle assemblyGO:0051225800.012
taxisGO:00423303040.012
tissue morphogenesisGO:00487292970.012
pole plasm mrna localizationGO:0019094490.012
positive regulation of mapk cascadeGO:0043410630.012
negative regulation of cell differentiationGO:00455961430.012
embryonic development via the syncytial blastodermGO:00017001480.012
regulation of cellular response to stressGO:0080135890.012
Human
regulation of immune responseGO:00507761180.012
sensory organ morphogenesisGO:00905962600.012
columnar cuboidal epithelial cell differentiationGO:00020652560.012
regulation of cellular protein metabolic processGO:00322682430.012
Human
digestive tract morphogenesisGO:00485461270.012
positive regulation of autophagyGO:0010508210.012
response to organophosphorusGO:004668320.012
molting cycle chitin based cuticleGO:0007591560.012
telencephalon developmentGO:002153720.012
detection of chemical stimulusGO:0009593930.012
cellular response to external stimulusGO:0071496660.012
Human
purine ribonucleoside triphosphate metabolic processGO:00092051190.012
anterograde synaptic vesicle transportGO:004849030.012
salivary gland histolysisGO:0035070880.012
cellular amine metabolic processGO:0044106120.012
regulation of phosphorus metabolic processGO:00511742100.012
cellular homeostasisGO:0019725800.011
hematopoietic progenitor cell differentiationGO:000224410.011
establishment of protein localizationGO:00451841630.011
Human
pyridine nucleotide metabolic processGO:001936220.011
programmed cell deathGO:00125012570.011
Human
positive regulation of synaptic transmission glutamatergicGO:005196830.011
post golgi vesicle mediated transportGO:0006892110.011
cellular response to oxygen containing compoundGO:1901701790.011
Human
regulation of cell morphogenesis involved in differentiationGO:0010769610.011
peptide metabolic processGO:0006518800.011
small molecule biosynthetic processGO:0044283370.011
response to alcoholGO:0097305950.011
Rat
jnk cascadeGO:0007254500.011
positive regulation of jun kinase activityGO:004350740.011
cellular protein localizationGO:00346131600.011
Human
regulation of anatomical structure morphogenesisGO:00226032420.011
mitotic chromosome condensationGO:0007076220.011
regulation of organelle organizationGO:00330431960.011
histolysisGO:00075591020.011
response to radiationGO:00093141550.011
response to copper ionGO:004668840.011
regulation of phosphorylationGO:00423251470.011
localization of cellGO:00516742570.011
Human
anion homeostasisGO:005508130.011
positive regulation of cell developmentGO:0010720610.011
steroid catabolic processGO:000670610.011
response to calcium ionGO:005159210.011
enzyme linked receptor protein signaling pathwayGO:00071671790.011
glycerolipid metabolic processGO:0046486340.011
regulation of cell maturationGO:1903429270.011
regulation of programmed cell deathGO:00430671520.011
Human
oocyte constructionGO:00073081120.011
toxin metabolic processGO:000940420.011
camera type eye morphogenesisGO:004859320.011
metal ion transportGO:0030001740.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.011
sensory perceptionGO:00076001960.011
peptidyl amino acid modificationGO:00181931050.011
Human
protein targetingGO:0006605640.011
maternal determination of anterior posterior axis embryoGO:0008358740.011
regulation of cell deathGO:00109411730.010
Human
respiratory system developmentGO:00605412130.010
rna catabolic processGO:0006401370.010
camera type eye developmentGO:004301040.010
brain developmentGO:00074201200.010
regulation of mapk cascadeGO:0043408920.010
dendrite morphogenesisGO:00488131990.010
response to heatGO:0009408630.010
establishment of protein localization to membraneGO:0090150110.010
protein localizationGO:00081042840.010
Human
ras protein signal transductionGO:0007265880.010
purine nucleotide metabolic processGO:00061631460.010
nicotinamide nucleotide metabolic processGO:004649620.010
positive regulation of hormone secretionGO:004688740.010
epithelium migrationGO:00901321480.010
Human
actin filament based processGO:00300292200.010
sensory perception of smellGO:0007608800.010

HDAC6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.072
inherited metabolic disorderDOID:65500.063
disease of metabolismDOID:001466700.063
nervous system diseaseDOID:86300.030
central nervous system diseaseDOID:33100.027
neurodegenerative diseaseDOID:128900.025
vascular diseaseDOID:17800.017
cardiovascular system diseaseDOID:128700.017
cancerDOID:16200.013
disease of cellular proliferationDOID:1456600.013
organ system cancerDOID:005068600.010