IMP: Integrative Multi-species Prediction

Drosophila melanogaster

33 known processes

Arp87C (Dmel_CG6174)

Actin-related protein 87C

(Aliases: Arp,Actr87C,ARP87C,ARP1,Dmel\CG6174,grid,Arp-1,CG6174,arp1,Arp1,gdl)

FLYBASE: FBgn0011745
Entrez: 41566
UniProtKB: P45889

Process Predictions
Disease Predictions

Arp87C biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
microtubule based transport	GO:0010970	42	0.993
retrograde axon cargo transport	GO:0008090	9	0.987
spindle organization	GO:0007051	253	0.789
mitotic spindle organization	GO:0007052	220	0.714
establishment of organelle localization	GO:0051656	122	0.689
single organism intracellular transport	GO:1902582	207	0.615
establishment or maintenance of cell polarity	GO:0007163	167	0.576
axon cargo transport	GO:0008088	29	0.572
organelle localization	GO:0051640	148	0.563
oocyte development	GO:0048599	124	0.520
establishment of nucleus localization	GO:0040023	26	0.514
microtubule organizing center organization	GO:0031023	168	0.465
regulation of developmental growth	GO:0048638	174	0.433
single organism cellular localization	GO:1902580	180	0.432
establishment or maintenance of bipolar cell polarity	GO:0061245	34	0.431
nucleus localization	GO:0051647	34	0.401
developmental growth	GO:0048589	280	0.395
cellular protein complex assembly	GO:0043623	71	0.378
negative regulation of gene expression	GO:0010629	387	0.363
rna localization	GO:0006403	115	0.345
chromosome organization	GO:0051276	360	0.344
mitotic nuclear division	GO:0007067	213	0.319
organelle fission	GO:0048285	340	0.318
protein complex biogenesis	GO:0070271	201	0.318
pronuclear migration	GO:0035046	4	0.305
intracellular signal transduction	GO:0035556	300	0.288
nuclear division	GO:0000280	332	0.270
organic substance transport	GO:0071702	257	0.264
negative regulation of cellular metabolic process	GO:0031324	382	0.251
cellular macromolecule localization	GO:0070727	220	0.235
endocytosis	GO:0006897	310	0.224
embryo development ending in birth or egg hatching	GO:0009792	152	0.220
vesicle mediated transport	GO:0016192	381	0.216
establishment of synaptic vesicle localization	GO:0097480	50	0.206
cell division	GO:0051301	248	0.201
cellular protein modification process	GO:0006464	438	0.189
transcription from rna polymerase ii promoter	GO:0006366	368	0.177
protein complex assembly	GO:0006461	200	0.175
nuclear migration	GO:0007097	20	0.173
actin filament based process	GO:0030029	220	0.170
chromosome segregation	GO:0007059	157	0.168
organelle assembly	GO:0070925	198	0.161
central nervous system development	GO:0007417	201	0.154
cytoskeleton dependent intracellular transport	GO:0030705	44	0.143
oocyte construction	GO:0007308	112	0.140
growth	GO:0040007	359	0.138
spindle elongation	GO:0051231	83	0.137
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.134
response to oxygen containing compound	GO:1901700	200	0.134
nucleobase containing compound transport	GO:0015931	56	0.131
intracellular transport	GO:0046907	228	0.129
protein localization	GO:0008104	284	0.127
synaptic vesicle transport	GO:0048489	50	0.126
establishment of localization in cell	GO:0051649	402	0.125
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.125
centrosome cycle	GO:0007098	137	0.123
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.122
single organism biosynthetic process	GO:0044711	206	0.120
cellular macromolecular complex assembly	GO:0034622	153	0.118
pole plasm oskar mrna localization	GO:0045451	46	0.116
microtubule based movement	GO:0007018	51	0.116
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.107
cellular protein localization	GO:0034613	160	0.107
pole plasm mrna localization	GO:0019094	49	0.101
cellular component disassembly	GO:0022411	46	0.100
establishment of cell polarity	GO:0030010	40	0.100
body morphogenesis	GO:0010171	2	0.100
vesicle localization	GO:0051648	55	0.099
establishment of spindle orientation	GO:0051294	18	0.098
protein transport	GO:0015031	155	0.098
regulation of protein metabolic process	GO:0051246	256	0.095
fertilization	GO:0009566	26	0.092
cytoplasm organization	GO:0007028	64	0.091
establishment or maintenance of apical basal cell polarity	GO:0035088	34	0.090
lateral inhibition	GO:0046331	206	0.085
synaptic vesicle localization	GO:0097479	53	0.084
columnar cuboidal epithelial cell development	GO:0002066	249	0.084
single fertilization	GO:0007338	24	0.084
cell proliferation	GO:0008283	299	0.083
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.082
regulation of notch signaling pathway	GO:0008593	100	0.081
ovarian follicle cell development	GO:0030707	248	0.081
regionalization	GO:0003002	416	0.080
cell migration	GO:0016477	238	0.076
biological adhesion	GO:0022610	138	0.072
nitrogen compound transport	GO:0071705	85	0.069
establishment of protein localization	GO:0045184	163	0.067
eye development	GO:0001654	323	0.064
regulation of multicellular organismal development	GO:2000026	414	0.062
regulation of transport	GO:0051049	181	0.062
positive regulation of developmental process	GO:0051094	143	0.060
rna transport	GO:0050658	46	0.060
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.058
cytoplasmic transport	GO:0016482	130	0.057
pole plasm rna localization	GO:0007316	52	0.056
oocyte axis specification	GO:0007309	108	0.055
macromolecular complex assembly	GO:0065003	256	0.055
regulation of microtubule based process	GO:0032886	49	0.055
regulation of organelle organization	GO:0033043	196	0.054
pole plasm assembly	GO:0007315	61	0.053
actin cytoskeleton organization	GO:0030036	206	0.052
establishment of rna localization	GO:0051236	47	0.052
cellular response to oxygen containing compound	GO:1901701	79	0.051
defense response	GO:0006952	300	0.051
regulation of ras protein signal transduction	GO:0046578	93	0.051
regulation of localization	GO:0032879	275	0.051
positive regulation of multicellular organismal process	GO:0051240	143	0.050
localization of cell	GO:0051674	257	0.050
positive regulation of macromolecule metabolic process	GO:0010604	405	0.050
regulation of growth	GO:0040008	233	0.049
regulation of cell proliferation	GO:0042127	163	0.048
intracellular protein transport	GO:0006886	104	0.048
establishment of vesicle localization	GO:0051650	51	0.048
regulation of cell size	GO:0008361	63	0.047
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.046
epithelial cell differentiation	GO:0030855	322	0.046
mitotic cell cycle phase transition	GO:0044772	138	0.046
negative regulation of biosynthetic process	GO:0009890	277	0.045
mapk cascade	GO:0000165	107	0.045
spindle assembly	GO:0051225	80	0.045
regulation of microtubule based movement	GO:0060632	9	0.044
larval development	GO:0002164	104	0.044
regulation of cellular catabolic process	GO:0031329	157	0.043
regulation of cell cycle	GO:0051726	291	0.041
negative regulation of signaling	GO:0023057	219	0.041
axon development	GO:0061564	297	0.041
male gamete generation	GO:0048232	201	0.040
regulation of cell morphogenesis	GO:0022604	163	0.039
cell motility	GO:0048870	251	0.039
regulation of cellular protein metabolic process	GO:0032268	243	0.038
phagocytosis	GO:0006909	215	0.037
negative regulation of cellular component organization	GO:0051129	108	0.036
centrosome localization	GO:0051642	14	0.035
nucleoside triphosphate metabolic process	GO:0009141	120	0.035
regulation of epithelial cell proliferation	GO:0050678	4	0.035
cellular response to organic substance	GO:0071310	132	0.035
spindle localization	GO:0051653	22	0.034
negative regulation of cell communication	GO:0010648	223	0.034
centrosome organization	GO:0051297	163	0.034
negative regulation of protein metabolic process	GO:0051248	85	0.034
ameboidal type cell migration	GO:0001667	151	0.034
protein modification process	GO:0036211	438	0.033
positive regulation of cell communication	GO:0010647	250	0.033
cellular response to endogenous stimulus	GO:0071495	80	0.033
positive regulation of signaling	GO:0023056	243	0.033
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.032
regulation of protein complex assembly	GO:0043254	42	0.032
response to radiation	GO:0009314	155	0.031
macromolecular complex disassembly	GO:0032984	37	0.031
compound eye photoreceptor cell differentiation	GO:0001751	140	0.031
positive regulation of synapse assembly	GO:0051965	29	0.030
response to abiotic stimulus	GO:0009628	341	0.030
organonitrogen compound catabolic process	GO:1901565	128	0.030
negative regulation of signal transduction	GO:0009968	206	0.030
positive regulation of gene expression	GO:0010628	290	0.030
positive regulation of developmental growth	GO:0048639	62	0.030
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.030
ribonucleotide metabolic process	GO:0009259	145	0.029
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.029
purine nucleotide catabolic process	GO:0006195	109	0.029
purine ribonucleoside metabolic process	GO:0046128	127	0.028
positive regulation of rna metabolic process	GO:0051254	271	0.027
regulation of cell projection organization	GO:0031344	92	0.027
positive regulation of nervous system development	GO:0051962	69	0.027
negative regulation of cell cycle process	GO:0010948	109	0.027
regulation of cellular component size	GO:0032535	98	0.027
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.027
regulation of nervous system development	GO:0051960	248	0.027
intracellular mrna localization	GO:0008298	66	0.027
positive regulation of transport	GO:0051050	92	0.026
organonitrogen compound metabolic process	GO:1901564	318	0.026
muscle structure development	GO:0061061	224	0.026
regulation of immune system process	GO:0002682	176	0.026
regulation of phosphate metabolic process	GO:0019220	210	0.026
proteolysis	GO:0006508	192	0.026
membrane depolarization	GO:0051899	4	0.026
meiotic cell cycle	GO:0051321	171	0.026
single organism carbohydrate metabolic process	GO:0044723	72	0.026
establishment of spindle localization	GO:0051293	22	0.025
regulation of multi organism process	GO:0043900	131	0.025
membrane organization	GO:0061024	112	0.025
meiotic spindle organization	GO:0000212	36	0.025
mrna transport	GO:0051028	15	0.025
negative regulation of cellular protein metabolic process	GO:0032269	85	0.025
negative regulation of cellular biosynthetic process	GO:0031327	277	0.024
organophosphate catabolic process	GO:0046434	112	0.024
autophagic vacuole assembly	GO:0000045	2	0.023
establishment of mitotic spindle orientation	GO:0000132	13	0.023
negative regulation of response to stimulus	GO:0048585	258	0.023
regulation of cellular ketone metabolic process	GO:0010565	3	0.023
epithelial cell development	GO:0002064	274	0.023
protein localization to organelle	GO:0033365	82	0.023
axis specification	GO:0009798	167	0.023
notch signaling pathway	GO:0007219	120	0.022
compound eye development	GO:0048749	307	0.022
mitochondrion localization	GO:0051646	17	0.022
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.022
mitotic spindle elongation	GO:0000022	81	0.022
purine ribonucleotide metabolic process	GO:0009150	145	0.022
regulation of synapse assembly	GO:0051963	94	0.021
protein polymerization	GO:0051258	42	0.021
regulation of cell differentiation	GO:0045595	302	0.021
regulation of cellular component movement	GO:0051270	42	0.021
anterior posterior axis specification embryo	GO:0008595	103	0.020
positive regulation of transcription dna templated	GO:0045893	266	0.020
anterior posterior pattern specification	GO:0009952	136	0.020
multicellular organismal aging	GO:0010259	140	0.020
metal ion transport	GO:0030001	74	0.019
synaptic transmission	GO:0007268	288	0.019
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.019
negative regulation of nervous system development	GO:0051961	92	0.019
secretion	GO:0046903	109	0.019
dorsal ventral pattern formation	GO:0009953	133	0.018
response to organic substance	GO:0010033	284	0.018
compound eye morphogenesis	GO:0001745	249	0.018
ribonucleotide catabolic process	GO:0009261	109	0.018
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.018
phosphorylation	GO:0016310	294	0.018
covalent chromatin modification	GO:0016569	106	0.018
oocyte differentiation	GO:0009994	145	0.018
positive regulation of biosynthetic process	GO:0009891	316	0.018
nucleoside metabolic process	GO:0009116	127	0.018
axonogenesis	GO:0007409	290	0.018
myotube cell development	GO:0014904	3	0.017
determination of adult lifespan	GO:0008340	137	0.017
cytoskeleton dependent cytokinesis	GO:0061640	81	0.017
positive regulation of response to stimulus	GO:0048584	323	0.017
positive regulation of cellular biosynthetic process	GO:0031328	316	0.017
cellular response to organonitrogen compound	GO:0071417	36	0.017
single organism membrane organization	GO:0044802	93	0.017
programmed cell death	GO:0012501	257	0.017
regulation of cell development	GO:0060284	215	0.017
proteasomal protein catabolic process	GO:0010498	59	0.017
anterior posterior axis specification	GO:0009948	109	0.017
response to organonitrogen compound	GO:0010243	75	0.016
regulation of phosphatase activity	GO:0010921	3	0.016
organic substance catabolic process	GO:1901575	308	0.016
negative regulation of cell cycle	GO:0045786	116	0.016
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	116	0.016
membrane fusion	GO:0061025	42	0.016
cellular response to extracellular stimulus	GO:0031668	64	0.016
ribonucleoside monophosphate catabolic process	GO:0009158	39	0.016
telencephalon development	GO:0021537	2	0.016
cellular response to chemical stimulus	GO:0070887	199	0.016
positive regulation of intracellular transport	GO:0032388	42	0.015
intracellular mrna localization involved in pattern specification process	GO:0060810	56	0.015
spermatogenesis	GO:0007283	200	0.015
embryonic axis specification	GO:0000578	107	0.015
negative regulation of intracellular signal transduction	GO:1902532	57	0.015
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.015
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	65	0.015
nucleic acid transport	GO:0050657	46	0.015
carbohydrate metabolic process	GO:0005975	82	0.015
intracellular mrna localization involved in anterior posterior axis specification	GO:0060811	53	0.014
regulation of phosphorus metabolic process	GO:0051174	210	0.014
tripartite regional subdivision	GO:0007351	103	0.014
protein targeting	GO:0006605	64	0.014
chromatin modification	GO:0016568	147	0.014
mitochondrion distribution	GO:0048311	10	0.014
carbohydrate derivative catabolic process	GO:1901136	118	0.014
secondary metabolic process	GO:0019748	75	0.014
regulation of synapse organization	GO:0050807	110	0.014
positive regulation of phosphorus metabolic process	GO:0010562	139	0.014
protein complex disassembly	GO:0043241	36	0.014
aging	GO:0007568	143	0.014
regulation of cell morphogenesis involved in differentiation	GO:0010769	61	0.013
positive regulation of cellular component organization	GO:0051130	156	0.013
rhabdomere development	GO:0042052	38	0.013
response to external biotic stimulus	GO:0043207	293	0.013
blastoderm segmentation	GO:0007350	159	0.013
carbohydrate derivative metabolic process	GO:1901135	217	0.013
homeostatic process	GO:0042592	199	0.013
meiotic cytokinesis	GO:0033206	33	0.013
reproductive system development	GO:0061458	74	0.013
regulation of mitotic cell cycle	GO:0007346	190	0.013
morphogenesis of an epithelium	GO:0002009	276	0.013
nucleotide catabolic process	GO:0009166	109	0.013
regulation of intracellular transport	GO:0032386	64	0.012
pigmentation	GO:0043473	75	0.012
negative regulation of multi organism process	GO:0043901	29	0.012
regulation of phosphorylation	GO:0042325	147	0.012
purine nucleotide metabolic process	GO:0006163	146	0.012
single organism catabolic process	GO:0044712	228	0.012
purine ribonucleoside catabolic process	GO:0046130	112	0.012
cellular protein complex disassembly	GO:0043624	35	0.012
neuromuscular junction development	GO:0007528	149	0.012
head development	GO:0060322	135	0.012
dephosphorylation	GO:0016311	51	0.012
cell growth	GO:0016049	108	0.012
regulation of behavior	GO:0050795	75	0.012
symbiosis encompassing mutualism through parasitism	GO:0044403	16	0.011
death	GO:0016265	284	0.011
regulation of neuron differentiation	GO:0045664	103	0.011
purine nucleoside metabolic process	GO:0042278	127	0.011
maternal determination of anterior posterior axis embryo	GO:0008358	74	0.011
response to other organism	GO:0051707	293	0.011
interspecies interaction between organisms	GO:0044419	16	0.011
cell death	GO:0008219	279	0.011
negative regulation of epithelial cell proliferation	GO:0050680	4	0.011
response to endogenous stimulus	GO:0009719	119	0.011
negative regulation of protein complex disassembly	GO:0043242	23	0.011
response to starvation	GO:0042594	97	0.011
multicellular organismal homeostasis	GO:0048871	41	0.011
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.011
mesoderm development	GO:0007498	78	0.011
ribonucleoside metabolic process	GO:0009119	127	0.011
protein ubiquitination	GO:0016567	70	0.010
positive regulation of binding	GO:0051099	4	0.010
regulation of neurogenesis	GO:0050767	158	0.010
synaptic vesicle endocytosis	GO:0048488	28	0.010
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.010
regulation of proteolysis	GO:0030162	87	0.010
purine nucleoside monophosphate catabolic process	GO:0009128	38	0.010
response to temperature stimulus	GO:0009266	106	0.010
nucleobase containing small molecule metabolic process	GO:0055086	174	0.010
regulation of protein modification process	GO:0031399	112	0.010
regulation of catabolic process	GO:0009894	170	0.010
ribose phosphate metabolic process	GO:0019693	145	0.010
sensory organ morphogenesis	GO:0090596	260	0.010
ion transport	GO:0006811	145	0.010
negative regulation of phosphate metabolic process	GO:0045936	45	0.010

Arp87C disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.029

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