IMP: Integrative Multi-species Prediction

Drosophila melanogaster

34 known processes

CG6178 (Dmel_CG6178)

CG6178 gene product from transcript CG6178-RA

(Aliases: Dmel\CG6178)

FLYBASE: FBgn0039156
Entrez: 42867
UniProtKB: Q9VCC6

Process Predictions
Disease Predictions

CG6178 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

Filter by process size:

Biological process	GO term ID	Process size	Probability	Func Analog Org
fatty acid metabolic process	GO:0006631	20	0.336
lipid catabolic process	GO:0016042	21	0.334	Fly
very long chain fatty acid metabolic process	GO:0000038	4	0.329
lipid modification	GO:0030258	24	0.242
lipid metabolic process	GO:0006629	121	0.208
cellular lipid catabolic process	GO:0044242	16	0.188	Fly
fatty acid catabolic process	GO:0009062	9	0.187	Fly
cellular catabolic process	GO:0044248	372	0.176	Fly
oxoacid metabolic process	GO:0043436	103	0.152
small molecule metabolic process	GO:0044281	305	0.151
monocarboxylic acid catabolic process	GO:0072329	10	0.150	Fly
catabolic process	GO:0009056	409	0.142	Fly
single organism catabolic process	GO:0044712	228	0.137	Fly
protein targeting to peroxisome	GO:0006625	2	0.132
acyl coa metabolic process	GO:0006637	3	0.121
carboxylic acid metabolic process	GO:0019752	92	0.119
fatty acid beta oxidation	GO:0006635	6	0.116
organic acid metabolic process	GO:0006082	103	0.112
organic substance transport	GO:0071702	257	0.110
lipid oxidation	GO:0034440	7	0.107
neurotransmitter metabolic process	GO:0042133	2	0.102
cholesterol homeostasis	GO:0042632	3	0.102
organic hydroxy compound metabolic process	GO:1901615	83	0.102
appendage development	GO:0048736	401	0.101
cellular lipid metabolic process	GO:0044255	83	0.100
peroxisome organization	GO:0007031	14	0.097
acetate ester metabolic process	GO:1900619	2	0.091
intracellular protein transmembrane transport	GO:0065002	4	0.089
fatty acid oxidation	GO:0019395	6	0.080
medium chain fatty acid metabolic process	GO:0051791	1	0.077
sterol homeostasis	GO:0055092	4	0.076
sulfur compound metabolic process	GO:0006790	59	0.076
organic substance catabolic process	GO:1901575	308	0.074	Fly
protein transmembrane transport	GO:0071806	4	0.070
thioester metabolic process	GO:0035383	3	0.070
cellular protein localization	GO:0034613	160	0.066
carboxylic acid catabolic process	GO:0046395	16	0.065	Fly
monocarboxylic acid metabolic process	GO:0032787	29	0.064
oxidation reduction process	GO:0055114	123	0.064
establishment of localization in cell	GO:0051649	402	0.064
cellular macromolecule localization	GO:0070727	220	0.063
imaginal disc derived appendage development	GO:0048737	399	0.062
organic acid catabolic process	GO:0016054	16	0.062	Fly
post embryonic appendage morphogenesis	GO:0035120	385	0.060
appendage morphogenesis	GO:0035107	397	0.059
small molecule catabolic process	GO:0044282	21	0.057	Fly
imaginal disc derived wing morphogenesis	GO:0007476	337	0.056
neurological system process	GO:0050877	358	0.054
positive regulation of biosynthetic process	GO:0009891	316	0.054
taxis	GO:0042330	304	0.054
establishment of protein localization to peroxisome	GO:0072663	2	0.053
single organism cellular localization	GO:1902580	180	0.052
wing disc morphogenesis	GO:0007472	344	0.051
vesicle mediated transport	GO:0016192	381	0.051
polyol biosynthetic process	GO:0046173	3	0.051
protein localization	GO:0008104	284	0.050
ion transmembrane transport	GO:0034220	122	0.050
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.048
protein transport	GO:0015031	155	0.048
positive regulation of cell communication	GO:0010647	250	0.048
androgen metabolic process	GO:0008209	1	0.046
protein localization to peroxisome	GO:0072662	2	0.045
single organism behavior	GO:0044708	391	0.045
regulation of transport	GO:0051049	181	0.044
estrogen metabolic process	GO:0008210	1	0.044
response to organic substance	GO:0010033	284	0.044	Fly
endocytosis	GO:0006897	310	0.043
organelle fission	GO:0048285	340	0.042
organonitrogen compound metabolic process	GO:1901564	318	0.042
intracellular transport	GO:0046907	228	0.042
lipid biosynthetic process	GO:0008610	46	0.041
male gamete generation	GO:0048232	201	0.041
single organism intracellular transport	GO:1902582	207	0.041
positive regulation of lipid metabolic process	GO:0045834	4	0.040
tube morphogenesis	GO:0035239	191	0.040
chemotaxis	GO:0006935	249	0.040
single organism biosynthetic process	GO:0044711	206	0.039
small molecule biosynthetic process	GO:0044283	37	0.039
regulation of localization	GO:0032879	275	0.039
single organism carbohydrate metabolic process	GO:0044723	72	0.037
axon guidance	GO:0007411	233	0.037
organophosphate metabolic process	GO:0019637	195	0.037
intracellular protein transmembrane import	GO:0044743	4	0.037
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.037
cellular protein modification process	GO:0006464	438	0.036
macromolecular complex assembly	GO:0065003	256	0.036
homeostatic process	GO:0042592	199	0.036
phagocytosis	GO:0006909	215	0.035
peroxisomal transport	GO:0043574	2	0.035
transmembrane transport	GO:0055085	139	0.035
ion transport	GO:0006811	145	0.035
response to external biotic stimulus	GO:0043207	293	0.034
neuron projection guidance	GO:0097485	241	0.034
protein complex biogenesis	GO:0070271	201	0.034
axonogenesis	GO:0007409	290	0.034
sulfur compound biosynthetic process	GO:0044272	16	0.033
response to biotic stimulus	GO:0009607	294	0.033
synaptic transmission	GO:0007268	288	0.033
cytoplasmic transport	GO:0016482	130	0.033
protein import	GO:0017038	55	0.032
hormone catabolic process	GO:0042447	3	0.031
axon development	GO:0061564	297	0.031
intracellular protein transport	GO:0006886	104	0.031
carbohydrate metabolic process	GO:0005975	82	0.031
acylglycerol biosynthetic process	GO:0046463	2	0.031
negative regulation of cellular metabolic process	GO:0031324	382	0.031
cellular ketone metabolic process	GO:0042180	24	0.030
protein modification process	GO:0036211	438	0.030
hormone metabolic process	GO:0042445	33	0.030
negative regulation of gene expression	GO:0010629	387	0.030
cell motility	GO:0048870	251	0.030
camera type eye development	GO:0043010	4	0.030
spermatogenesis	GO:0007283	200	0.029
cholesterol transport	GO:0030301	2	0.029
regulation of hormone levels	GO:0010817	40	0.029
monocarboxylic acid transport	GO:0015718	3	0.029
developmental growth	GO:0048589	280	0.029
connective tissue development	GO:0061448	3	0.029
carbohydrate derivative metabolic process	GO:1901135	217	0.029
regulation of intracellular signal transduction	GO:1902531	236	0.028
regulation of steroid metabolic process	GO:0019218	2	0.028
regulation of cellular component biogenesis	GO:0044087	201	0.028
positive regulation of signaling	GO:0023056	243	0.028
triglyceride biosynthetic process	GO:0019432	2	0.028
establishment of protein localization	GO:0045184	163	0.027
digestive tract morphogenesis	GO:0048546	127	0.027
defense response	GO:0006952	300	0.026
regulation of cellular protein metabolic process	GO:0032268	243	0.026
membrane organization	GO:0061024	112	0.026
kidney development	GO:0001822	3	0.026
anion transport	GO:0006820	41	0.026
endomembrane system organization	GO:0010256	119	0.025
response to lipopolysaccharide	GO:0032496	4	0.025
positive regulation of signal transduction	GO:0009967	223	0.025
protein targeting	GO:0006605	64	0.025
programmed cell death	GO:0012501	257	0.025
cellular amine metabolic process	GO:0044106	12	0.024
growth	GO:0040007	359	0.024
acetylcholine metabolic process	GO:0008291	2	0.024
cellular response to chemical stimulus	GO:0070887	199	0.024	Fly
regulation of lipid transport	GO:0032368	3	0.024
amine metabolic process	GO:0009308	12	0.024
regulation of cellular ketone metabolic process	GO:0010565	3	0.024
negative regulation of cellular biosynthetic process	GO:0031327	277	0.024
positive regulation of transport	GO:0051050	92	0.023
adult behavior	GO:0030534	137	0.023
establishment of protein localization to organelle	GO:0072594	62	0.023
epithelial cell differentiation	GO:0030855	322	0.023
protein complex assembly	GO:0006461	200	0.023
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.023
organic cyclic compound catabolic process	GO:1901361	168	0.023
single organism membrane organization	GO:0044802	93	0.023
forebrain development	GO:0030900	2	0.022
cell migration	GO:0016477	238	0.022
epithelium migration	GO:0090132	148	0.022
digestive tract development	GO:0048565	149	0.022
glycosyl compound metabolic process	GO:1901657	127	0.022
alcohol metabolic process	GO:0006066	25	0.022
proteolysis	GO:0006508	192	0.021
dorsal appendage formation	GO:0046843	47	0.021
chaeta development	GO:0022416	97	0.021
regulation of protein metabolic process	GO:0051246	256	0.021
negative regulation of biosynthetic process	GO:0009890	277	0.021
neutral lipid biosynthetic process	GO:0046460	2	0.021
phosphorylation	GO:0016310	294	0.021
regulation of molecular function	GO:0065009	217	0.021
immune system process	GO:0002376	347	0.021
lipid homeostasis	GO:0055088	33	0.021
cellular response to organic substance	GO:0071310	132	0.020	Fly
response to drug	GO:0042493	17	0.020
columnar cuboidal epithelial cell development	GO:0002066	249	0.020
nuclear division	GO:0000280	332	0.020
positive regulation of response to stimulus	GO:0048584	323	0.020
regulation of multicellular organismal development	GO:2000026	414	0.020
death	GO:0016265	284	0.020
neuromuscular synaptic transmission	GO:0007274	67	0.020
kidney epithelium development	GO:0072073	3	0.020
cellular amino acid metabolic process	GO:0006520	61	0.019
positive regulation of multicellular organismal process	GO:0051240	143	0.019
cation transport	GO:0006812	110	0.019
purine containing compound metabolic process	GO:0072521	155	0.019
body morphogenesis	GO:0010171	2	0.019
tube development	GO:0035295	244	0.018
lipid localization	GO:0010876	54	0.018
negative regulation of signal transduction	GO:0009968	206	0.018	Fly
regulation of cellular localization	GO:0060341	136	0.018
steroid catabolic process	GO:0006706	1	0.018
response to nutrient levels	GO:0031667	114	0.018
positive regulation of cellular biosynthetic process	GO:0031328	316	0.018
cellular nitrogen compound catabolic process	GO:0044270	165	0.018
ameboidal type cell migration	GO:0001667	151	0.018
protein complex disassembly	GO:0043241	36	0.018
cell death	GO:0008219	279	0.018
negative regulation of cellular component organization	GO:0051129	108	0.018
dna metabolic process	GO:0006259	227	0.017
organic anion transport	GO:0015711	28	0.017
morphogenesis of an epithelium	GO:0002009	276	0.017
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.017
organonitrogen compound catabolic process	GO:1901565	128	0.017
defense response to other organism	GO:0098542	225	0.017
intracellular signal transduction	GO:0035556	300	0.017
regionalization	GO:0003002	416	0.017
anion homeostasis	GO:0055081	3	0.017
response to glucose	GO:0009749	2	0.017
response to hexose	GO:0009746	3	0.017
cell division	GO:0051301	248	0.017
response to monosaccharide	GO:0034284	4	0.017
chemical homeostasis	GO:0048878	92	0.017
digestive system development	GO:0055123	149	0.017
cell adhesion	GO:0007155	136	0.017
gland development	GO:0048732	191	0.016
carbohydrate derivative biosynthetic process	GO:1901137	85	0.016
regulation of growth	GO:0040008	233	0.016
embryonic morphogenesis	GO:0048598	206	0.016
epithelial cell migration	GO:0010631	148	0.016
one carbon metabolic process	GO:0006730	3	0.016
positive regulation of cell motility	GO:2000147	3	0.016
aromatic compound catabolic process	GO:0019439	166	0.016
regulation of catalytic activity	GO:0050790	185	0.016
biological adhesion	GO:0022610	138	0.016
response to other organism	GO:0051707	293	0.016
nephron epithelium development	GO:0072009	3	0.016
negative regulation of cell communication	GO:0010648	223	0.016	Fly
heterocycle catabolic process	GO:0046700	166	0.016
response to nitrogen compound	GO:1901698	90	0.016	Fly
response to alcohol	GO:0097305	95	0.016
fat soluble vitamin metabolic process	GO:0006775	1	0.015
positive regulation of reactive oxygen species metabolic process	GO:2000379	0	0.015
ribose phosphate metabolic process	GO:0019693	145	0.015
phosphatidylethanolamine metabolic process	GO:0046337	1	0.015
response to bacterium	GO:0009617	198	0.015
response to temperature stimulus	GO:0009266	106	0.015
positive regulation of protein metabolic process	GO:0051247	128	0.015
telencephalon development	GO:0021537	2	0.015
regulation of cellular amine metabolic process	GO:0033238	3	0.015
secretion	GO:0046903	109	0.015
positive regulation of rna biosynthetic process	GO:1902680	266	0.015
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.015	Fly
ribonucleoside metabolic process	GO:0009119	127	0.015
regulation of cell substrate adhesion	GO:0010810	2	0.015
alditol phosphate metabolic process	GO:0052646	2	0.015
neutral lipid metabolic process	GO:0006638	12	0.015	Fly
cellular hormone metabolic process	GO:0034754	23	0.015
nucleoside phosphate metabolic process	GO:0006753	162	0.015
regulation of cell cycle process	GO:0010564	181	0.014
protein phosphorylation	GO:0006468	169	0.014
xenobiotic catabolic process	GO:0042178	1	0.014
regulation of cell differentiation	GO:0045595	302	0.014
transcription from rna polymerase ii promoter	GO:0006366	368	0.014
vitamin metabolic process	GO:0006766	2	0.014
ethanolamine containing compound metabolic process	GO:0042439	4	0.014
ovarian follicle cell development	GO:0030707	248	0.014
glycerolipid catabolic process	GO:0046503	3	0.014	Fly
positive regulation of cell migration	GO:0030335	2	0.014
nucleocytoplasmic transport	GO:0006913	72	0.014
negative regulation of rna metabolic process	GO:0051253	251	0.014
regulation of nervous system development	GO:0051960	248	0.014
nucleotide metabolic process	GO:0009117	161	0.014
organelle assembly	GO:0070925	198	0.014
negative regulation of signaling	GO:0023057	219	0.014	Fly
regulation of programmed cell death	GO:0043067	152	0.013
spermatid differentiation	GO:0048515	114	0.013
regulation of phosphate metabolic process	GO:0019220	210	0.013
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.013
protein localization to organelle	GO:0033365	82	0.013
tissue morphogenesis	GO:0048729	297	0.013
nuclear transport	GO:0051169	72	0.013
positive regulation of cellular protein metabolic process	GO:0032270	118	0.013
apoptotic process	GO:0006915	159	0.013
negative regulation of sequence specific dna binding transcription factor activity	GO:0043433	4	0.013
regulation of notch signaling pathway	GO:0008593	100	0.013
regulation of cholesterol transport	GO:0032374	1	0.013
acylglycerol metabolic process	GO:0006639	12	0.013	Fly
cellular component assembly involved in morphogenesis	GO:0010927	151	0.013
wound healing	GO:0042060	75	0.013
epithelial cell development	GO:0002064	274	0.013
peptidyl amino acid modification	GO:0018193	105	0.013
response to starvation	GO:0042594	97	0.013
compound eye development	GO:0048749	307	0.013
cell proliferation	GO:0008283	299	0.013
neurotransmitter catabolic process	GO:0042135	1	0.013
nephron development	GO:0072006	3	0.013
cellular biogenic amine catabolic process	GO:0042402	1	0.012
cellular response to oxygen containing compound	GO:1901701	79	0.012	Fly
response to organophosphorus	GO:0046683	2	0.012
nucleobase containing small molecule metabolic process	GO:0055086	174	0.012
neutral lipid catabolic process	GO:0046461	3	0.012	Fly
long chain fatty acid metabolic process	GO:0001676	3	0.012
localization of cell	GO:0051674	257	0.012
regulation of neurotransmitter levels	GO:0001505	38	0.012
immune response	GO:0006955	246	0.012
acylglycerol catabolic process	GO:0046464	3	0.012	Fly
positive regulation of macromolecule metabolic process	GO:0010604	405	0.012
mitotic nuclear division	GO:0007067	213	0.012
cation transmembrane transport	GO:0098655	88	0.012
immune response regulating signaling pathway	GO:0002764	2	0.012
regulation of sterol transport	GO:0032371	1	0.012
eggshell formation	GO:0030703	105	0.012
nitrogen compound transport	GO:0071705	85	0.012
purine nucleoside metabolic process	GO:0042278	127	0.012
negative regulation of cellular protein metabolic process	GO:0032269	85	0.012
response to wounding	GO:0009611	94	0.012
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.012
steroid biosynthetic process	GO:0006694	16	0.012
gastrulation with mouth forming first	GO:0001703	36	0.012
positive regulation of gene expression	GO:0010628	290	0.012
regulation of proteolysis	GO:0030162	87	0.012
lateral inhibition	GO:0046331	206	0.012
organonitrogen compound biosynthetic process	GO:1901566	117	0.012
regulation of immune system process	GO:0002682	176	0.012
purine ribonucleotide metabolic process	GO:0009150	145	0.012
skeletal muscle fiber development	GO:0048741	3	0.012
protein targeting to nucleus	GO:0044744	51	0.012
glycoprotein biosynthetic process	GO:0009101	41	0.012
tissue migration	GO:0090130	155	0.012
regulation of lipid metabolic process	GO:0019216	15	0.012
regulation of system process	GO:0044057	36	0.012
regulation of transferase activity	GO:0051338	58	0.012
hormone biosynthetic process	GO:0042446	20	0.011
cellular macromolecular complex assembly	GO:0034622	153	0.011
negative regulation of developmental process	GO:0051093	201	0.011
cuticle development	GO:0042335	86	0.011
cellular response to hexose stimulus	GO:0071331	1	0.011
regulation of cell proliferation	GO:0042127	163	0.011
regulation of anatomical structure size	GO:0090066	163	0.011
negative regulation of protein metabolic process	GO:0051248	85	0.011
defense response to bacterium	GO:0042742	178	0.011
triglyceride catabolic process	GO:0019433	3	0.011	Fly
myotube cell development	GO:0014904	3	0.011
nephron tubule development	GO:0072080	3	0.011
retina development in camera type eye	GO:0060041	4	0.011
response to copper ion	GO:0046688	4	0.011
locomotory behavior	GO:0007626	176	0.011
kidney morphogenesis	GO:0060993	3	0.011
negative regulation of transcription dna templated	GO:0045892	237	0.011
exocytosis	GO:0006887	28	0.011
generation of precursor metabolites and energy	GO:0006091	42	0.011
organic hydroxy compound catabolic process	GO:1901616	4	0.011
central nervous system development	GO:0007417	201	0.011
cellular response to carbohydrate stimulus	GO:0071322	4	0.011
regulation of cell cycle	GO:0051726	291	0.011
cellular response to molecule of bacterial origin	GO:0071219	3	0.011
renal system development	GO:0072001	72	0.011
regulation of cellular amino acid metabolic process	GO:0006521	0	0.011
cell aging	GO:0007569	2	0.011
nucleoside metabolic process	GO:0009116	127	0.011
immune response activating signal transduction	GO:0002757	2	0.011
triglyceride metabolic process	GO:0006641	12	0.011	Fly
dendrite morphogenesis	GO:0048813	199	0.011
notch signaling pathway	GO:0007219	120	0.011
regulation of cell size	GO:0008361	63	0.011
negative regulation of molecular function	GO:0044092	51	0.011
spindle organization	GO:0007051	253	0.011
nephron tubule morphogenesis	GO:0072078	3	0.011
regulation of cell development	GO:0060284	215	0.011
regulation of phosphorus metabolic process	GO:0051174	210	0.011
proteoglycan metabolic process	GO:0006029	10	0.011
signal transduction by phosphorylation	GO:0023014	107	0.011
regulation of cell death	GO:0010941	173	0.011
response to fungus	GO:0009620	50	0.011
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	65	0.010
regulation of multi organism process	GO:0043900	131	0.010
regulation of phosphorylation	GO:0042325	147	0.010
steroid metabolic process	GO:0008202	20	0.010
regulation of protein complex assembly	GO:0043254	42	0.010
cellular response to monosaccharide stimulus	GO:0071326	2	0.010
terminal button organization	GO:0072553	19	0.010
negative regulation of rna biosynthetic process	GO:1902679	240	0.010
response to oxygen containing compound	GO:1901700	200	0.010	Fly
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	116	0.010	Fly
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.010
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.010
cellular response to organic cyclic compound	GO:0071407	32	0.010
insecticide catabolic process	GO:0046701	1	0.010
neuron recognition	GO:0008038	101	0.010
peripheral nervous system development	GO:0007422	52	0.010
hindbrain development	GO:0030902	2	0.010
positive regulation of protein modification process	GO:0031401	58	0.010
organophosphate catabolic process	GO:0046434	112	0.010
maintenance of location	GO:0051235	73	0.010
cell cycle arrest	GO:0007050	4	0.010
mapk cascade	GO:0000165	107	0.010
regulation of intracellular transport	GO:0032386	64	0.010

CG6178 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.069
disease of metabolism	DOID:0014667	0.035
inherited metabolic disorder	DOID:655	0.033
nervous system disease	DOID:863	0.020
cardiovascular system disease	DOID:1287	0.017
kidney disease	DOID:557	0.014
urinary system disease	DOID:18	0.014
renal tubular transport disease	DOID:447	0.014
diabetes mellitus	DOID:9351	0.013
type 2 diabetes mellitus	DOID:9352	0.013
acquired metabolic disease	DOID:0060158	0.013
glucose metabolism disease	DOID:4194	0.013
carbohydrate metabolism disease	DOID:0050013	0.013
central nervous system disease	DOID:331	0.012
artery disease	DOID:0050828	0.012
vascular disease	DOID:178	0.012

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