Drosophila melanogaster

22 known processes

Him (Dmel_CG15064)

Holes in muscle

(Aliases: Dmel\CG15064,CG15064,him)

Him biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
myoblast fusionGO:0007520430.234
enzyme linked receptor protein signaling pathwayGO:00071671790.158
negative regulation of gene expressionGO:00106293870.152
positive regulation of gene expressionGO:00106282900.131
eye developmentGO:00016543230.130
regulation of multicellular organismal developmentGO:20000264140.129
regulation of epithelial cell proliferationGO:005067840.125
cell proliferationGO:00082832990.124
regulation of transcription from rna polymerase ii promoterGO:00063573780.122
developmental maturationGO:00217001720.114
camera type eye developmentGO:004301040.110
kidney developmentGO:000182230.108
regionalizationGO:00030024160.107
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.098
positive regulation of transcription dna templatedGO:00458932660.097
positive regulation of response to stimulusGO:00485843230.096
regulation of developmental growthGO:00486381740.096
growthGO:00400073590.095
regulation of anatomical structure morphogenesisGO:00226032420.089
positive regulation of rna metabolic processGO:00512542710.089
immune system processGO:00023763470.087
sensory organ morphogenesisGO:00905962600.087
regulation of cell differentiationGO:00455953020.087
negative regulation of cellular metabolic processGO:00313243820.086
positive regulation of cellular biosynthetic processGO:00313283160.084
open tracheal system developmentGO:00074242040.082
negative regulation of signalingGO:00230572190.080
negative regulation of signal transductionGO:00099682060.078
connective tissue developmentGO:006144830.078
regulation of cell proliferationGO:00421271630.078
deathGO:00162652840.074
cell motilityGO:00488702510.073
cell deathGO:00082192790.073
regulation of cell deathGO:00109411730.073
extracellular structure organizationGO:0043062460.072
multi organism behaviorGO:00517051750.069
programmed cell deathGO:00125012570.067
transcription from rna polymerase ii promoterGO:00063663680.067
positive regulation of biosynthetic processGO:00098913160.064
central nervous system developmentGO:00074172010.064
columnar cuboidal epithelial cell differentiationGO:00020652560.063
regulation of immune system processGO:00026821760.063
amine metabolic processGO:0009308120.062
negative regulation of cell communicationGO:00106482230.061
body morphogenesisGO:001017120.060
regulation of cell developmentGO:00602842150.060
eye morphogenesisGO:00485922600.059
embryonic development via the syncytial blastodermGO:00017001480.059
organ growthGO:0035265560.058
negative regulation of cell cycle processGO:00109481090.057
negative regulation of response to stimulusGO:00485852580.056
cellular ketone metabolic processGO:0042180240.055
syncytium formationGO:0006949430.055
positive regulation of rna biosynthetic processGO:19026802660.054
multi organism reproductive behaviorGO:00447051210.054
tube developmentGO:00352952440.053
single organism behaviorGO:00447083910.052
response to organic substanceGO:00100332840.052
muscle organ developmentGO:00075171270.052
embryo development ending in birth or egg hatchingGO:00097921520.052
compound eye developmentGO:00487493070.050
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.050
regulation of cellular amino acid metabolic processGO:000652100.050
positive regulation of signalingGO:00230562430.049
negative regulation of cell cycleGO:00457861160.049
response to woundingGO:0009611940.048
positive regulation of macromolecule biosynthetic processGO:00105572830.048
negative regulation of multicellular organismal processGO:00512411420.048
positive regulation of macromolecule metabolic processGO:00106044050.047
response to abiotic stimulusGO:00096283410.047
regulation of programmed cell deathGO:00430671520.046
regulation of apoptotic processGO:00429811300.045
regulation of proteolysisGO:0030162870.045
multi multicellular organism processGO:00447061230.045
regulation of muscle organ developmentGO:0048634130.045
blastoderm segmentationGO:00073501590.044
regulation of cellular ketone metabolic processGO:001056530.044
digestive system developmentGO:00551231490.043
positive regulation of cell communicationGO:00106472500.043
positive regulation of nitrogen compound metabolic processGO:00511733540.043
embryonic pattern specificationGO:00098801740.043
organic acid metabolic processGO:00060821030.043
nuclear divisionGO:00002803320.042
negative regulation of nucleobase containing compound metabolic processGO:00459342610.042
sensory perception of mechanical stimulusGO:0050954720.042
apoptotic processGO:00069151590.042
regulation of cell cycle processGO:00105641810.041
regulation of cellular protein metabolic processGO:00322682430.041
kidney epithelium developmentGO:007207330.041
cellular amine metabolic processGO:0044106120.041
negative regulation of nitrogen compound metabolic processGO:00511722650.041
taxisGO:00423303040.041
regulation of phosphorus metabolic processGO:00511742100.041
negative regulation of developmental processGO:00510932010.041
visceral muscle developmentGO:0007522140.040
organonitrogen compound metabolic processGO:19015643180.040
negative regulation of macromolecule biosynthetic processGO:00105582700.040
imaginal disc derived appendage morphogenesisGO:00351143950.040
synapse organizationGO:00508081960.040
imaginal disc derived appendage developmentGO:00487373990.040
regulation of cell sizeGO:0008361630.039
regulation of response to external stimulusGO:00321011150.039
cell maturationGO:00484691440.039
chromosome organizationGO:00512763600.038
respiratory system developmentGO:00605412130.038
neurological system processGO:00508773580.038
nephron developmentGO:007200630.038
cell divisionGO:00513012480.038
regulation of cell cycleGO:00517262910.038
positive regulation of nucleobase containing compound metabolic processGO:00459353320.038
phosphorylationGO:00163102940.037
morphogenesis of embryonic epitheliumGO:0016331940.037
cell cycle phase transitionGO:00447701400.037
small molecule metabolic processGO:00442813050.037
proteolysisGO:00065081920.036
mesodermal cell fate specificationGO:000750120.036
columnar cuboidal epithelial cell developmentGO:00020662490.036
negative regulation of cell proliferationGO:0008285690.036
negative regulation of nucleic acid templated transcriptionGO:19035072400.036
negative regulation of programmed cell deathGO:0043069720.035
epithelial cell differentiationGO:00308553220.035
stem cell differentiationGO:00488631170.035
oxoacid metabolic processGO:00434361030.034
localization of cellGO:00516742570.034
axon guidanceGO:00074112330.034
embryonic morphogenesisGO:00485982060.034
sensory perceptionGO:00076001960.034
neuron projection guidanceGO:00974852410.033
regulation of protein metabolic processGO:00512462560.033
forebrain developmentGO:003090020.033
response to other organismGO:00517072930.033
single organism intracellular transportGO:19025822070.033
establishment of localization in cellGO:00516494020.033
positive regulation of signal transductionGO:00099672230.033
syncytium formation by plasma membrane fusionGO:0000768430.033
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281250.033
negative regulation of cell deathGO:0060548810.033
positive regulation of nucleic acid templated transcriptionGO:19035082660.033
morphogenesis of an epitheliumGO:00020092760.033
negative regulation of rna biosynthetic processGO:19026792400.033
appendage morphogenesisGO:00351073970.032
telencephalon developmentGO:002153720.032
anterior posterior pattern specificationGO:00099521360.032
regulation of response to stressGO:00801342000.032
response to biotic stimulusGO:00096072940.032
negative regulation of transcription dna templatedGO:00458922370.032
compound eye morphogenesisGO:00017452490.032
ovarian follicle cell developmentGO:00307072480.032
imaginal disc pattern formationGO:0007447910.031
regulation of cellular amine metabolic processGO:003323830.031
segmentationGO:00352822070.031
mrna metabolic processGO:00160711240.031
negative regulation of apoptotic processGO:0043066630.031
protein modification processGO:00362114380.031
epithelial cell developmentGO:00020642740.030
developmental growthGO:00485892800.030
nephron epithelium developmentGO:007200930.030
regulation of molecular functionGO:00650092170.030
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.030
synaptic transmissionGO:00072682880.030
regulation of mitotic cell cycleGO:00073461900.030
peptidyl amino acid modificationGO:00181931050.030
digestive tract developmentGO:00485651490.030
immune responseGO:00069552460.030
regulation of phosphate metabolic processGO:00192202100.029
regulation of notch signaling pathwayGO:00085931000.029
photoreceptor cell differentiationGO:00465301700.029
carboxylic acid metabolic processGO:0019752920.029
cell fate determinationGO:0001709910.029
head developmentGO:00603221350.029
limb developmentGO:006017310.029
regulation of intracellular signal transductionGO:19025312360.029
skeletal muscle fiber developmentGO:004874130.029
dorsal ventral pattern formationGO:00099531330.028
rhythmic processGO:00485111060.028
regulation of localizationGO:00328792750.028
negative regulation of biosynthetic processGO:00098902770.028
positive regulation of growthGO:0045927750.028
tissue morphogenesisGO:00487292970.028
chemotaxisGO:00069352490.028
renal tubule morphogenesisGO:0061333440.028
cellular protein modification processGO:00064644380.028
lateral inhibitionGO:00463312060.027
appendage developmentGO:00487364010.027
circadian rhythmGO:00076231050.027
outflow tract morphogenesisGO:000315140.027
gland developmentGO:00487321910.027
eye photoreceptor cell differentiationGO:00017541450.027
sex differentiationGO:0007548810.027
regulation of growthGO:00400082330.027
histone modificationGO:00165701060.027
brain developmentGO:00074201200.027
camera type eye morphogenesisGO:004859320.027
exocrine system developmentGO:00352721620.027
embryonic hindgut morphogenesisGO:0048619480.027
reproductive behaviorGO:00190981220.027
multicellular organismal reproductive behaviorGO:00330571100.027
vesicle mediated transportGO:00161923810.027
myotube cell developmentGO:001490430.026
negative regulation of rna metabolic processGO:00512532510.026
wound healingGO:0042060750.026
negative regulation of cellular biosynthetic processGO:00313272770.026
cellular response to organic substanceGO:00713101320.026
tube morphogenesisGO:00352391910.026
regulation of cell morphogenesisGO:00226041630.026
regulation of cellular component sizeGO:0032535980.026
endodermal cell differentiationGO:003598730.026
defense responseGO:00069523000.026
mitotic nuclear divisionGO:00070672130.026
cellular amino acid metabolic processGO:0006520610.025
positive regulation of developmental processGO:00510941430.025
alternative mrna splicing via spliceosomeGO:0000380600.025
wing disc morphogenesisGO:00074723440.025
cellular protein localizationGO:00346131600.025
post embryonic appendage morphogenesisGO:00351203850.025
regulation of cell shapeGO:00083601130.025
regulation of phosphorylationGO:00423251470.025
phagocytosisGO:00069092150.025
neuromuscular junction developmentGO:00075281490.025
catabolic processGO:00090564090.024
regulation of immune responseGO:00507761180.024
establishment of organelle localizationGO:00516561220.024
salivary gland developmentGO:00074311620.024
regulation of organ growthGO:0046620420.024
cell fate specificationGO:0001708710.024
regulation of nervous system developmentGO:00519602480.024
regulation of catalytic activityGO:00507901850.024
somatic muscle developmentGO:0007525660.024
positive regulation of response to external stimulusGO:0032103440.023
retina development in camera type eyeGO:006004140.023
synapse assemblyGO:00074161430.023
cellular response to dna damage stimulusGO:00069742230.023
regulation of innate immune responseGO:0045088710.023
organelle fissionGO:00482853400.023
regulation of embryonic developmentGO:0045995680.023
erbb signaling pathwayGO:0038127580.022
response to endogenous stimulusGO:00097191190.022
transmembrane transportGO:00550851390.022
protein localizationGO:00081042840.022
positive regulation of proteolysisGO:0045862520.022
actin filament based processGO:00300292200.022
regenerationGO:0031099160.022
protein phosphorylationGO:00064681690.022
cell cell signaling involved in cell fate commitmentGO:00451682100.022
positive regulation of cell deathGO:0010942690.022
mesoderm developmentGO:0007498780.022
response to alcoholGO:0097305950.022
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.022
cuticle developmentGO:0042335860.021
dna metabolic processGO:00062592270.021
molting cycle chitin based cuticleGO:0007591560.021
regulation of dna metabolic processGO:0051052340.021
salivary gland morphogenesisGO:00074351450.021
establishment or maintenance of cell polarityGO:00071631670.021
establishment of protein localizationGO:00451841630.021
wnt signaling pathwayGO:0016055980.021
endocytosisGO:00068973100.021
digestive tract morphogenesisGO:00485461270.021
formation of organ boundaryGO:0010160300.021
hindbrain developmentGO:003090220.021
cellular macromolecule localizationGO:00707272200.021
regulation of wound healingGO:0061041130.021
covalent chromatin modificationGO:00165691060.021
formation of anatomical boundaryGO:0048859370.021
wing disc pattern formationGO:0035222660.021
chromatin organizationGO:00063252070.021
indole containing compound biosynthetic processGO:004243540.021
regulation of neuron deathGO:1901214260.020
urogenital system developmentGO:0001655720.020
sterol homeostasisGO:005509240.020
regulation of wnt signaling pathwayGO:0030111680.020
positive regulation of response to woundingGO:1903036150.020
gland morphogenesisGO:00226121450.020
rna processingGO:00063961470.020
epidermal growth factor receptor signaling pathwayGO:0007173580.020
spermatogenesisGO:00072832000.020
histone acetylationGO:0016573380.019
negative regulation of nervous system developmentGO:0051961920.019
regulation of alternative mrna splicing via spliceosomeGO:0000381600.019
cytoskeleton dependent cytokinesisGO:0061640810.019
cranial nerve developmentGO:002154510.019
regulation of rna splicingGO:0043484690.019
organelle localizationGO:00516401480.019
positive regulation of protein metabolic processGO:00512471280.019
macromolecule catabolic processGO:00090571610.019
hindgut developmentGO:0061525580.019
gliogenesisGO:0042063800.019
negative regulation of erbb signaling pathwayGO:1901185290.019
positive regulation of programmed cell deathGO:0043068620.019
regulation of cell projection organizationGO:0031344920.018
molting cycle processGO:0022404290.018
developmental growth involved in morphogenesisGO:0060560650.018
dorsal closureGO:0007391790.018
endomembrane system organizationGO:00102561190.018
organic substance transportGO:00717022570.018
renal system developmentGO:0072001720.018
ectodermal placode morphogenesisGO:007169740.018
regulation of neuron projection developmentGO:0010975690.018
stem cell developmentGO:0048864790.018
cholesterol homeostasisGO:004263230.018
eye antennal disc morphogenesisGO:0007455340.018
adult locomotory behaviorGO:0008344760.018
chromosome segregationGO:00070591570.018
axon developmentGO:00615642970.018
cuticle pattern formationGO:0035017270.018
muscle tissue developmentGO:0060537300.017
muscle tissue morphogenesisGO:006041520.017
molting cycleGO:0042303560.017
positive regulation of cellular protein metabolic processGO:00322701180.017
response to external biotic stimulusGO:00432072930.017
response to monosaccharideGO:003428440.017
nucleobase containing small molecule metabolic processGO:00550861740.017
epithelial tube morphogenesisGO:0060562880.017
negative regulation of mitotic cell cycleGO:00459301090.017
spermatid developmentGO:0007286980.017
developmental inductionGO:003112830.017
endodermal cell fate commitmentGO:000171130.017
response to hexoseGO:000974630.017
intracellular signal transductionGO:00355563000.017
neuron recognitionGO:00080381010.017
regulation of catabolic processGO:00098941700.017
negative regulation of epidermal growth factor receptor signaling pathwayGO:0042059290.017
muscle structure developmentGO:00610612240.017
male mating behaviorGO:0060179700.017
glial cell migrationGO:0008347310.016
negative regulation of cell developmentGO:0010721620.016
larval visceral muscle developmentGO:000752390.016
regulation of mrna metabolic processGO:1903311720.016
positive regulation of muscle organ developmentGO:004863660.016
positive regulation of multicellular organismal processGO:00512401430.016
cellular response to chemical stimulusGO:00708871990.016
oxidation reduction processGO:00551141230.016
regulation of synapse assemblyGO:0051963940.016
posttranscriptional regulation of gene expressionGO:00106081450.016
regulation of erbb signaling pathwayGO:1901184420.016
cytoplasmic transportGO:00164821300.016
muscle attachmentGO:0016203360.016
internal protein amino acid acetylationGO:0006475380.016
circadian behaviorGO:0048512760.016
protein localization to organelleGO:0033365820.016
defense response to other organismGO:00985422250.016
cellular lipid metabolic processGO:0044255830.016
cytokinesisGO:0000910900.016
spermatid differentiationGO:00485151140.016
hindgut morphogenesisGO:0007442580.016
positive regulation of cellular amino acid metabolic processGO:004576400.016
rhythmic behaviorGO:0007622760.016
negative regulation of protein metabolic processGO:0051248850.016
embryonic organ developmentGO:0048568500.016
regulation of cell substrate adhesionGO:001081020.016
positive regulation of hydrolase activityGO:0051345780.016
single organism catabolic processGO:00447122280.016
mrna processingGO:00063971040.015
malpighian tubule developmentGO:0072002640.015
regulation of peptidase activityGO:0052547390.015
gastrulationGO:0007369700.015
anion homeostasisGO:005508130.015
defense response to bacteriumGO:00427421780.015
rna splicing via transesterification reactionsGO:0000375730.015
regulation of reproductive processGO:2000241540.015
motor neuron axon guidanceGO:0008045580.015
chorion containing eggshell formationGO:00073041050.015
axonogenesisGO:00074092900.015
organic substance catabolic processGO:19015753080.015
negative regulation of epithelial cell proliferationGO:005068040.015
locomotory behaviorGO:00076261760.015
tripartite regional subdivisionGO:00073511030.015
mitotic cell cycle phase transitionGO:00447721380.015
innate immune responseGO:00450871440.015
ion transportGO:00068111450.015
organophosphate metabolic processGO:00196371950.015
actin cytoskeleton organizationGO:00300362060.015
response to lipopolysaccharideGO:003249640.015
mushroom body developmentGO:0016319700.015
negative regulation of cellular protein metabolic processGO:0032269850.015
stem cell maintenanceGO:0019827670.015
establishment of planar polarityGO:0001736870.015
regulation of anatomical structure sizeGO:00900661630.015
positive regulation of developmental growthGO:0048639620.015
positive regulation of apoptotic signaling pathwayGO:200123540.015
regulation of hydrolase activityGO:0051336970.014
cell cell junction assemblyGO:0007043380.014
peptidyl lysine acetylationGO:0018394390.014
cellular catabolic processGO:00442483720.014
cellular response to extracellular stimulusGO:0031668640.014
protein modification by small protein conjugation or removalGO:00706471060.014
neuron deathGO:0070997270.014
actin filament organizationGO:00070151260.014
agingGO:00075681430.014
response to radiationGO:00093141550.014
mesenchymal cell differentiationGO:004876210.014
striated muscle cell differentiationGO:0051146900.014
single organism cellular localizationGO:19025801800.014
malpighian tubule morphogenesisGO:0007443440.014
axis specificationGO:00097981670.014
embryonic axis specificationGO:00005781070.014
synaptic target recognitionGO:0008039450.014
regulation of mrna processingGO:0050684710.014
golgi organizationGO:0007030660.014
positive regulation of catalytic activityGO:00430851180.014
regulation of mapk cascadeGO:0043408920.014
nephron morphogenesisGO:007202830.014
ameboidal type cell migrationGO:00016671510.014
muscle cell developmentGO:0055001500.014
ovarian nurse cell to oocyte transportGO:0007300270.014
oocyte differentiationGO:00099941450.014
development of primary male sexual characteristicsGO:004654690.014
striated muscle tissue developmentGO:0014706270.014
stem cell proliferationGO:0072089880.014
cellular macromolecule catabolic processGO:00442651360.014
regulation of organelle organizationGO:00330431960.014
germ cell migrationGO:0008354430.014
regulation of circadian rhythmGO:0042752490.013
limb morphogenesisGO:003510810.013
response to glucoseGO:000974920.013
nephron tubule developmentGO:007208030.013
protein maturationGO:0051604710.013
regulation of neurogenesisGO:00507671580.013
positive regulation of lipid metabolic processGO:004583440.013
regulation of endopeptidase activityGO:0052548360.013
response to organic cyclic compoundGO:0014070890.013
positive regulation of molecular functionGO:00440931360.013
extrinsic apoptotic signaling pathwayGO:009719110.013
cellular response to external stimulusGO:0071496660.013
hematopoietic or lymphoid organ developmentGO:0048534570.013
mapk cascadeGO:00001651070.013
negative regulation of cellular component organizationGO:00511291080.013
regulation of mrna splicing via spliceosomeGO:0048024640.013
positive regulation of defense responseGO:0031349590.013
immune system developmentGO:0002520570.013
embryonic heart tube developmentGO:0035050220.013
skeletal muscle organ developmentGO:0060538480.013
eggshell formationGO:00307031050.013
regulation of epidermal growth factor receptor signaling pathwayGO:0042058420.013
kidney morphogenesisGO:006099330.013
axis elongationGO:000340130.013
cell type specific apoptotic processGO:0097285380.013
compound eye photoreceptor cell differentiationGO:00017511400.013
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.013
cell cycle arrestGO:000705040.013
protein catabolic processGO:00301631010.013
negative regulation of developmental growthGO:0048640640.013
peptidyl lysine modificationGO:0018205570.013
single organism membrane organizationGO:0044802930.012
response to painGO:004826530.012
regulation of mitotic cell cycle phase transitionGO:19019901300.012
defense response to gram negative bacteriumGO:0050829940.012
nephron epithelium morphogenesisGO:007208830.012
monocarboxylic acid transportGO:001571830.012
spindle organizationGO:00070512530.012
organelle assemblyGO:00709251980.012
negative regulation of cell differentiationGO:00455961430.012
epithelial cell proliferationGO:0050673150.012
positive regulation of neuron apoptotic processGO:004352510.012
response to bacteriumGO:00096171980.012
protein acylationGO:0043543420.012
renal tubule developmentGO:0061326640.012
cardiovascular system developmentGO:0072358820.012
neuroblast proliferationGO:0007405740.012
positive regulation of cellular amine metabolic processGO:003324000.012
internal peptidyl lysine acetylationGO:0018393380.012
nucleoside phosphate metabolic processGO:00067531620.012
protein ubiquitinationGO:0016567700.012
positive regulation of cellular component organizationGO:00511301560.012
protein modification by small protein conjugationGO:0032446790.012
regulation of striated muscle tissue developmentGO:001620250.012
secretionGO:00469031090.012
positive regulation of cell cycleGO:0045787430.012
positive regulation of wound healingGO:0090303120.012
neuron remodelingGO:0016322290.012
response to nutrient levelsGO:00316671140.012
regulation of neuron apoptotic processGO:0043523160.012
positive regulation of phosphorus metabolic processGO:00105621390.012
smoothened signaling pathwayGO:0007224490.012
ectodermal placode developmentGO:007169640.012
epithelial cell migrationGO:00106311480.012
branching morphogenesis of an epithelial tubeGO:0048754450.012
response to oxygen containing compoundGO:19017002000.012
gastrulation involving germ band extensionGO:0010004360.012
reproductive structure developmentGO:0048608740.012
negative regulation of cell cycle phase transitionGO:19019881030.012
protein acetylationGO:0006473390.012

Him disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.085
musculoskeletal system diseaseDOID:1700.042
cardiovascular system diseaseDOID:128700.037
vascular diseaseDOID:17800.033
connective tissue diseaseDOID:6500.023
bone diseaseDOID:008000100.023
artery diseaseDOID:005082800.020
hypertensionDOID:1076300.018
disease of cellular proliferationDOID:1456600.017
nervous system diseaseDOID:86300.016
cancerDOID:16200.014
organ system cancerDOID:005068600.013
bone development diseaseDOID:008000600.012