Drosophila melanogaster

53 known processes

Smg6 (Dmel_CG6369)

CG6369 gene product from transcript CG6369-RA

(Aliases: Dmel\CG6369,SMG6,dSMG6,CG6369)

Smg6 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of cellular biosynthetic processGO:00313283160.262
catabolic processGO:00090564090.207
sperm individualizationGO:0007291480.191
regulation of multicellular organismal developmentGO:20000264140.181
organelle fissionGO:00482853400.180
cellular catabolic processGO:00442483720.178
peptide metabolic processGO:0006518800.171
ribose phosphate metabolic processGO:00196931450.154
male meiosis cytokinesisGO:0007112260.150
ion transmembrane transportGO:00342201220.149
response to nutrient levelsGO:00316671140.141
cellular macromolecule catabolic processGO:00442651360.129
deathGO:00162652840.129
organic substance transportGO:00717022570.129
rhythmic processGO:00485111060.127
organonitrogen compound metabolic processGO:19015643180.126
regulation of multi organism processGO:00439001310.124
spermatid developmentGO:0007286980.123
nucleus organizationGO:0006997450.108
protein modification by small protein conjugation or removalGO:00706471060.108
dna metabolic processGO:00062592270.105
Human
protein localizationGO:00081042840.105
ras protein signal transductionGO:0007265880.104
heterocycle catabolic processGO:00467001660.100
regulation of mitotic cell cycle phase transitionGO:19019901300.100
modification dependent protein catabolic processGO:0019941780.098
cellular nitrogen compound catabolic processGO:00442701650.097
regulation of small gtpase mediated signal transductionGO:0051056930.097
regulation of nervous system developmentGO:00519602480.095
response to abiotic stimulusGO:00096283410.095
positive regulation of nitrogen compound metabolic processGO:00511733540.095
proteolysisGO:00065081920.094
nuclear divisionGO:00002803320.091
negative regulation of signalingGO:00230572190.089
positive regulation of gene expressionGO:00106282900.088
establishment of localization in cellGO:00516494020.087
vesicle mediated transportGO:00161923810.085
macromolecule catabolic processGO:00090571610.085
kidney developmentGO:000182230.082
protein catabolic processGO:00301631010.081
regulation of gene expression epigeneticGO:00400291280.080
pigmentationGO:0043473750.077
negative regulation of signal transductionGO:00099682060.077
cellular response to uvGO:0034644120.077
cellular amide metabolic processGO:0043603800.077
aromatic compound catabolic processGO:00194391660.075
meiotic cell cycleGO:00513211710.075
transmembrane transportGO:00550851390.074
carbohydrate derivative metabolic processGO:19011352170.074
positive regulation of nucleic acid templated transcriptionGO:19035082660.074
regulation of ras protein signal transductionGO:0046578930.071
regulation of nuclear divisionGO:0051783580.068
ubiquitin dependent protein catabolic processGO:0006511780.067
single organism behaviorGO:00447083910.066
histone h2a ubiquitinationGO:003352220.065
positive regulation of macromolecule metabolic processGO:00106044050.064
small gtpase mediated signal transductionGO:0007264880.064
regulation of cell differentiationGO:00455953020.064
purine containing compound catabolic processGO:00725231120.062
mitochondrion organizationGO:0007005650.062
positive regulation of cysteine type endopeptidase activityGO:2001056240.062
body morphogenesisGO:001017120.062
secretionGO:00469031090.061
positive regulation of macromolecule biosynthetic processGO:00105572830.060
establishment of organelle localizationGO:00516561220.057
cytoplasmic transportGO:00164821300.056
organic acid transportGO:0015849180.055
regulation of localizationGO:00328792750.054
dendrite developmentGO:00163582040.054
dna biosynthetic processGO:0071897240.053
eye pigment metabolic processGO:0042441330.052
response to extracellular stimulusGO:00099911160.052
regulation of transportGO:00510491810.052
negative regulation of cell communicationGO:00106482230.052
dna integrity checkpointGO:0031570810.052
cell cycle phase transitionGO:00447701400.051
protein transportGO:00150311550.051
regulation of protein metabolic processGO:00512462560.048
protein localization to organelleGO:0033365820.047
negative regulation of mitotic cell cycle phase transitionGO:19019911030.047
ion transportGO:00068111450.047
organic substance catabolic processGO:19015753080.047
regulation of cell cycle processGO:00105641810.047
response to starvationGO:0042594970.046
circulatory system developmentGO:0072359820.046
endocytosisGO:00068973100.046
cell deathGO:00082192790.046
intracellular protein transportGO:00068861040.045
organic cyclic compound catabolic processGO:19013611680.045
regulation of protein catabolic processGO:0042176550.045
adult locomotory behaviorGO:0008344760.044
embryo development ending in birth or egg hatchingGO:00097921520.044
morphogenesis of an epitheliumGO:00020092760.044
protein ubiquitinationGO:0016567700.043
nucleobase containing small molecule metabolic processGO:00550861740.043
cell divisionGO:00513012480.043
nucleoside catabolic processGO:00091641120.043
segmentationGO:00352822070.043
meiotic cytokinesisGO:0033206330.042
regulation of cell cycleGO:00517262910.042
nucleoside triphosphate catabolic processGO:00091431080.042
protein complex biogenesisGO:00702712010.042
developmental pigmentationGO:0048066680.042
proteolysis involved in cellular protein catabolic processGO:0051603830.041
cell cycle checkpointGO:0000075950.041
positive regulation of production of molecular mediator of immune responseGO:0002702280.040
cellular protein catabolic processGO:0044257830.040
macromolecular complex disassemblyGO:0032984370.040
regulation of cell deathGO:00109411730.040
negative regulation of gene expressionGO:00106293870.039
eggshell chorion gene amplificationGO:000730790.039
regulation of synapse assemblyGO:0051963940.039
posttranscriptional regulation of gene expressionGO:00106081450.039
cellular response to extracellular stimulusGO:0031668640.038
regulation of apoptotic processGO:00429811300.038
ribonucleoside triphosphate catabolic processGO:00092031080.038
nucleobase containing compound catabolic processGO:00346551650.038
regionalizationGO:00030024160.037
nucleotide metabolic processGO:00091171610.037
cellularizationGO:0007349900.037
nucleoside phosphate metabolic processGO:00067531620.036
positive regulation of multicellular organismal processGO:00512401430.036
posttranscriptional gene silencingGO:0016441460.035
positive regulation of biosynthetic processGO:00098913160.035
cellular response to external stimulusGO:0071496660.035
negative regulation of cell cycle phase transitionGO:19019881030.035
nucleotide catabolic processGO:00091661090.035
post embryonic appendage morphogenesisGO:00351203850.034
positive regulation of response to stimulusGO:00485843230.034
modification dependent macromolecule catabolic processGO:0043632790.034
regulation of catabolic processGO:00098941700.033
single organism catabolic processGO:00447122280.033
single organism biosynthetic processGO:00447112060.033
regulation of organelle organizationGO:00330431960.033
purine nucleoside triphosphate metabolic processGO:00091441190.033
regulation of proteolysisGO:0030162870.032
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.032
regulation of transcription from rna polymerase ii promoterGO:00063573780.031
regulation of hydrolase activityGO:0051336970.031
mitotic sister chromatid segregationGO:0000070870.031
response to inorganic substanceGO:0010035440.031
regulation of cell developmentGO:00602842150.031
organophosphate metabolic processGO:00196371950.030
programmed cell deathGO:00125012570.030
regulation of mitotic cell cycleGO:00073461900.030
ribonucleoside catabolic processGO:00424541120.030
positive regulation of protein metabolic processGO:00512471280.030
positive regulation of signalingGO:00230562430.030
purine containing compound metabolic processGO:00725211550.029
dendrite morphogenesisGO:00488131990.029
purine nucleoside catabolic processGO:00061521120.029
monocarboxylic acid transportGO:001571830.029
neurological system processGO:00508773580.029
purine ribonucleoside metabolic processGO:00461281270.029
cellular response to abiotic stimulusGO:0071214580.029
nuclear transportGO:0051169720.029
regulation of programmed cell deathGO:00430671520.028
cellular response to dna damage stimulusGO:00069742230.028
urogenital system developmentGO:0001655720.028
ocellus pigment metabolic processGO:0046158190.028
homeostatic processGO:00425921990.028
Human
dna amplificationGO:0006277110.027
positive regulation of nucleobase containing compound metabolic processGO:00459353320.027
cellular macromolecule localizationGO:00707272200.027
imaginal disc derived wing morphogenesisGO:00074763370.027
growthGO:00400073590.027
regulation of cellular component biogenesisGO:00440872010.026
purine nucleoside triphosphate catabolic processGO:00091461080.026
cellular protein localizationGO:00346131600.026
synapse organizationGO:00508081960.026
purine ribonucleotide catabolic processGO:00091541090.026
biological adhesionGO:00226101380.026
positive regulation of wnt signaling pathwayGO:0030177250.026
sister chromatid segregationGO:0000819920.026
regulation of cellular ketone metabolic processGO:001056530.026
negative regulation of response to stimulusGO:00485852580.025
regulation of synapse structure and activityGO:00508031280.025
protein modification processGO:00362114380.025
positive regulation of transcription dna templatedGO:00458932660.025
organonitrogen compound catabolic processGO:19015651280.024
positive regulation of antimicrobial peptide productionGO:0002225280.024
gene silencingGO:00164581380.024
regulation of cellular catabolic processGO:00313291570.024
regulation of response to stressGO:00801342000.024
gene silencing by rnaGO:0031047570.024
rna phosphodiester bond hydrolysisGO:0090501170.023
mitotic cell cycle checkpointGO:0007093880.023
negative regulation of developmental processGO:00510932010.023
apoptotic processGO:00069151590.022
small molecule metabolic processGO:00442813050.022
mitotic nuclear divisionGO:00070672130.022
organonitrogen compound biosynthetic processGO:19015661170.022
regulation of cell shapeGO:00083601130.022
purine ribonucleoside triphosphate metabolic processGO:00092051190.022
glycosyl compound metabolic processGO:19016571270.022
rna interferenceGO:0016246270.022
regulation of mitosisGO:0007088560.022
regulation of anatomical structure sizeGO:00900661630.021
nucleoside triphosphate metabolic processGO:00091411200.021
nucleoside metabolic processGO:00091161270.021
wing disc morphogenesisGO:00074723440.021
regulation of cell cycle phase transitionGO:19019871300.020
regulation of phosphatase activityGO:001092130.020
anion transportGO:0006820410.020
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101180.020
positive regulation of phosphate metabolic processGO:00459371390.020
regulation of wnt signaling pathwayGO:0030111680.020
negative regulation of transforming growth factor beta receptor signaling pathwayGO:003051240.020
mitotic cell cycle phase transitionGO:00447721380.019
hemopoiesisGO:0030097460.019
purine nucleoside metabolic processGO:00422781270.019
regulation of gene silencingGO:0060968630.019
response to other organismGO:00517072930.019
regulation of dna repairGO:000628250.019
negative regulation of biosynthetic processGO:00098902770.019
positive regulation of catalytic activityGO:00430851180.019
molting cycleGO:0042303560.018
regulation of cellular localizationGO:00603411360.018
carbohydrate derivative catabolic processGO:19011361180.018
cardiovascular system developmentGO:0072358820.018
protein complex disassemblyGO:0043241360.018
negative regulation of multicellular organismal processGO:00512411420.018
larval developmentGO:00021641040.018
positive regulation of signal transductionGO:00099672230.018
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.018
establishment of protein localization to organelleGO:0072594620.018
positive regulation of developmental processGO:00510941430.018
microtubule polymerization or depolymerizationGO:0031109390.018
positive regulation of phosphorus metabolic processGO:00105621390.018
meiotic nuclear divisionGO:00071261510.017
mrna transportGO:0051028150.017
embryonic morphogenesisGO:00485982060.017
positive regulation of hydrolase activityGO:0051345780.017
rna catabolic processGO:0006401370.017
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.017
negative regulation of cellular protein metabolic processGO:0032269850.017
regulation of response to dna damage stimulusGO:2001020230.017
negative regulation of cellular catabolic processGO:0031330340.017
regulation of humoral immune responseGO:0002920510.017
positive regulation of cell communicationGO:00106472500.017
regulation of cellular protein metabolic processGO:00322682430.016
regulation of meiosisGO:004002030.016
proteasomal protein catabolic processGO:0010498590.016
eye photoreceptor cell developmentGO:0042462810.016
imaginal disc derived appendage developmentGO:00487373990.016
positive regulation of stem cell differentiationGO:200073830.016
regulation of molecular functionGO:00650092170.016
protein modification by small protein removalGO:0070646280.016
cellular protein complex assemblyGO:0043623710.016
negative regulation of cell cycleGO:00457861160.016
regulation of cellular response to stressGO:0080135890.016
circadian sleep wake cycle sleepGO:0050802230.016
nucleoside phosphate catabolic processGO:19012921100.016
organic acid metabolic processGO:00060821030.015
protein complex assemblyGO:00064612000.015
regulation of neurogenesisGO:00507671580.015
rrna processingGO:000636430.015
oxoacid metabolic processGO:00434361030.015
microtubule polymerizationGO:0046785150.015
inorganic ion transmembrane transportGO:0098660730.015
regulation of cell morphogenesisGO:00226041630.015
regulation of synaptic growth at neuromuscular junctionGO:0008582890.014
protein importGO:0017038550.014
phosphorylationGO:00163102940.014
male courtship behavior veined wing extensionGO:0048065220.014
translationGO:0006412690.014
response to monosaccharideGO:003428440.014
positive regulation of catabolic processGO:00098961050.014
metal ion transportGO:0030001740.014
negative regulation of notch signaling pathwayGO:0045746410.014
tube developmentGO:00352952440.014
phagocytosisGO:00069092150.014
cell growthGO:00160491080.014
ribonucleoside triphosphate metabolic processGO:00091991190.014
negative regulation of nitrogen compound metabolic processGO:00511722650.014
organelle assemblyGO:00709251980.014
regulation of nucleoside metabolic processGO:0009118500.014
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.014
positive regulation of transportGO:0051050920.014
positive regulation of apoptotic processGO:0043065470.014
response to hexoseGO:000974630.014
positive regulation of programmed cell deathGO:0043068620.014
signal transduction in response to dna damageGO:004277030.014
circadian rhythmGO:00076231050.014
intracellular protein transmembrane transportGO:006500240.014
oocyte fate determinationGO:0030716270.014
eye pigmentationGO:0048069430.014
neuromuscular junction developmentGO:00075281490.014
nuclear transcribed mrna catabolic process deadenylation dependent decayGO:0000288140.014
protein modification by small protein conjugationGO:0032446790.013
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.013
ribonucleotide catabolic processGO:00092611090.013
negative regulation of protein metabolic processGO:0051248850.013
negative regulation of nervous system developmentGO:0051961920.013
positive regulation of cellular catabolic processGO:0031331950.013
postreplication repairGO:000630120.013
purine nucleotide metabolic processGO:00061631460.013
antimicrobial peptide productionGO:0002775460.013
regulation of translationGO:0006417560.013
purine ribonucleoside triphosphate catabolic processGO:00092071080.013
negative regulation of phosphatidylinositol 3 kinase signalingGO:001406740.013
negative regulation of cellular component organizationGO:00511291080.013
positive regulation of insulin receptor signaling pathwayGO:004662830.013
nephron developmentGO:007200630.013
eye developmentGO:00016543230.013
positive regulation of rna biosynthetic processGO:19026802660.013
cellular homeostasisGO:0019725800.013
antimicrobial humoral responseGO:0019730990.012
regulation of cell divisionGO:0051302720.012
dna damage checkpointGO:0000077780.012
positive regulation of humoral immune responseGO:0002922280.012
gliogenesisGO:0042063800.012
carbohydrate metabolic processGO:0005975820.012
humoral immune responseGO:00069591170.012
renal system developmentGO:0072001720.012
dorsal ventral pattern formationGO:00099531330.012
appendage morphogenesisGO:00351073970.012
negative regulation of transferase activityGO:0051348180.012
wnt signaling pathwayGO:0016055980.012
single organism nuclear importGO:1902593510.012
gtp metabolic processGO:0046039720.012
cellular response to radiationGO:0071478520.012
regulation of cuticle pigmentationGO:0048079160.012
negative regulation of cellular metabolic processGO:00313243820.012
dna repairGO:0006281540.012
nucleotide excision repairGO:000628980.011
purine nucleotide catabolic processGO:00061951090.011
regulation of catalytic activityGO:00507901850.011
positive regulation of nervous system developmentGO:0051962690.011
response to calcium ionGO:005159210.011
regulation of ras gtpase activityGO:0032318380.011
response to biotic stimulusGO:00096072940.011
glycosyl compound catabolic processGO:19016581120.011
negative regulation of macromolecule biosynthetic processGO:00105582700.011
nucleocytoplasmic transportGO:0006913720.011
adult behaviorGO:00305341370.011
single organism intracellular transportGO:19025822070.011
nucleobase containing compound transportGO:0015931560.011
regulation of phosphorus metabolic processGO:00511742100.011
regulation of behaviorGO:0050795750.011
cellular macromolecular complex assemblyGO:00346221530.011
imaginal disc derived appendage morphogenesisGO:00351143950.011
regulation of circadian rhythmGO:0042752490.011
organophosphate catabolic processGO:00464341120.011
imaginal disc derived wing margin morphogenesisGO:0008587410.011
male gamete generationGO:00482322010.011
response to temperature stimulusGO:00092661060.011
circadian sleep wake cycle processGO:0022410240.011
cell cell signaling involved in cell fate commitmentGO:00451682100.010
cellular response to ionizing radiationGO:0071479150.010
regulation of cysteine type endopeptidase activityGO:2000116270.010
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.010
carboxylic acid metabolic processGO:0019752920.010
single organism membrane buddingGO:190259120.010
centrosome organizationGO:00512971630.010
embryonic pattern specificationGO:00098801740.010
cellular component disassemblyGO:0022411460.010
antibacterial peptide productionGO:0002778220.010
compound eye photoreceptor cell differentiationGO:00017511400.010
protein processingGO:0016485680.010
negative regulation of mitotic cell cycleGO:00459301090.010
rhythmic behaviorGO:0007622760.010
regulation of response to biotic stimulusGO:0002831630.010
reciprocal meiotic recombinationGO:0007131190.010
agingGO:00075681430.010
regulation of hemocyte proliferationGO:0035206370.010
nucleus localizationGO:0051647340.010
positive regulation of protein transportGO:0051222370.010

Smg6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
urinary system diseaseDOID:1800.299
disease of anatomical entityDOID:700.299
kidney diseaseDOID:55700.299
renal tubular transport diseaseDOID:44700.299
nervous system diseaseDOID:86300.098
central nervous system diseaseDOID:33100.098
vascular diseaseDOID:17800.019
cardiovascular system diseaseDOID:128700.019
neurodegenerative diseaseDOID:128900.013
musculoskeletal system diseaseDOID:1700.011