Drosophila melanogaster

0 known processes

Cirl (Dmel_CG8639)

CG8639 gene product from transcript CG8639-RC

(Aliases: Dmel\CG8639,CG8639,BcDNA:GH07331,anon-WO0170980.7,dcirl,anon-WO0170980.8,CIRL)

Cirl biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
oligosaccharide biosynthetic processGO:0009312100.266
regulation of cell differentiationGO:00455953020.153
tube developmentGO:00352952440.116
negative regulation of cellular metabolic processGO:00313243820.105
protein modification processGO:00362114380.080
positive regulation of response to stimulusGO:00485843230.079
regionalizationGO:00030024160.079
negative regulation of rna metabolic processGO:00512532510.076
eye developmentGO:00016543230.075
regulation of transcription from rna polymerase ii promoterGO:00063573780.074
compound eye photoreceptor developmentGO:0042051780.073
negative regulation of cellular biosynthetic processGO:00313272770.071
tube morphogenesisGO:00352391910.071
cellular protein modification processGO:00064644380.069
establishment of localization in cellGO:00516494020.068
axon developmentGO:00615642970.066
appendage developmentGO:00487364010.066
negative regulation of biosynthetic processGO:00098902770.062
negative regulation of macromolecule biosynthetic processGO:00105582700.062
appendage morphogenesisGO:00351073970.062
positive regulation of nitrogen compound metabolic processGO:00511733540.061
oocyte constructionGO:00073081120.060
respiratory system developmentGO:00605412130.059
negative regulation of transcription dna templatedGO:00458922370.057
vesicle mediated transportGO:00161923810.055
epithelial cell differentiationGO:00308553220.054
digestive tract morphogenesisGO:00485461270.052
taxisGO:00423303040.051
axonogenesisGO:00074092900.051
negative regulation of developmental processGO:00510932010.050
cell motilityGO:00488702510.050
brain developmentGO:00074201200.049
Rat
forebrain developmentGO:003090020.049
photoreceptor cell differentiationGO:00465301700.049
synapse organizationGO:00508081960.047
Rat
negative regulation of nitrogen compound metabolic processGO:00511722650.047
synaptic transmissionGO:00072682880.046
Rat
cell cell signaling involved in cell fate commitmentGO:00451682100.046
embryonic morphogenesisGO:00485982060.046
organic substance catabolic processGO:19015753080.046
positive regulation of nucleic acid templated transcriptionGO:19035082660.045
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.045
extracellular structure organizationGO:0043062460.044
negative regulation of nucleobase containing compound metabolic processGO:00459342610.043
growthGO:00400073590.042
positive regulation of rna biosynthetic processGO:19026802660.042
open tracheal system developmentGO:00074242040.041
spermatogenesisGO:00072832000.041
dendrite developmentGO:00163582040.041
eye morphogenesisGO:00485922600.040
adult behaviorGO:00305341370.040
organonitrogen compound metabolic processGO:19015643180.039
embryonic pattern specificationGO:00098801740.039
cellular catabolic processGO:00442483720.039
positive regulation of biosynthetic processGO:00098913160.039
positive regulation of nucleobase containing compound metabolic processGO:00459353320.038
digestive tract developmentGO:00485651490.038
male gamete generationGO:00482322010.038
transcription from rna polymerase ii promoterGO:00063663680.038
single organism intracellular transportGO:19025822070.038
digestive system developmentGO:00551231490.038
eye photoreceptor cell developmentGO:0042462810.038
gastrulationGO:0007369700.037
negative regulation of nucleic acid templated transcriptionGO:19035072400.037
humoral immune responseGO:00069591170.037
regulation of multicellular organismal developmentGO:20000264140.037
Rat
cardiovascular system developmentGO:0072358820.037
developmental maturationGO:00217001720.037
Rat
morphogenesis of an epitheliumGO:00020092760.036
axon guidanceGO:00074112330.036
positive regulation of signal transductionGO:00099672230.036
positive regulation of gene expressionGO:00106282900.035
maternal determination of anterior posterior axis embryoGO:0008358740.035
compound eye developmentGO:00487493070.035
response to organic substanceGO:00100332840.035
positive regulation of cellular biosynthetic processGO:00313283160.035
positive regulation of macromolecule metabolic processGO:00106044050.035
positive regulation of transcription dna templatedGO:00458932660.034
wing disc morphogenesisGO:00074723440.034
negative regulation of signalingGO:00230572190.034
positive regulation of rna metabolic processGO:00512542710.034
catabolic processGO:00090564090.034
mapk cascadeGO:00001651070.034
imaginal disc derived appendage developmentGO:00487373990.033
compound eye photoreceptor cell differentiationGO:00017511400.033
intracellular signal transductionGO:00355563000.033
Rat
regulation of multi organism processGO:00439001310.033
response to biotic stimulusGO:00096072940.033
dendrite morphogenesisGO:00488131990.033
imaginal disc derived appendage morphogenesisGO:00351143950.033
negative regulation of response to stimulusGO:00485852580.033
negative regulation of rna biosynthetic processGO:19026792400.032
negative regulation of multicellular organismal processGO:00512411420.032
compound eye morphogenesisGO:00017452490.032
carbohydrate derivative metabolic processGO:19011352170.032
organic acid metabolic processGO:00060821030.032
lateral inhibitionGO:00463312060.032
single organism carbohydrate metabolic processGO:0044723720.032
tissue morphogenesisGO:00487292970.032
regulation of localizationGO:00328792750.032
segmentationGO:00352822070.031
deathGO:00162652840.031
biological adhesionGO:00226101380.031
Rat
single organism biosynthetic processGO:00447112060.031
post embryonic appendage morphogenesisGO:00351203850.031
cell deathGO:00082192790.031
chemotaxisGO:00069352490.031
eye photoreceptor cell differentiationGO:00017541450.031
imaginal disc derived wing morphogenesisGO:00074763370.031
negative regulation of gene expressionGO:00106293870.030
blastoderm segmentationGO:00073501590.030
response to external biotic stimulusGO:00432072930.030
epithelial cell developmentGO:00020642740.029
sensory organ morphogenesisGO:00905962600.029
photoreceptor cell developmentGO:0042461960.029
columnar cuboidal epithelial cell developmentGO:00020662490.029
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.029
immune system processGO:00023763470.029
anterior posterior pattern specificationGO:00099521360.029
central nervous system developmentGO:00074172010.028
Rat
neuron projection guidanceGO:00974852410.028
defense response to other organismGO:00985422250.028
programmed cell deathGO:00125012570.028
intracellular transportGO:00469072280.027
negative regulation of cell differentiationGO:00455961430.027
regulation of response to external stimulusGO:00321011150.027
positive regulation of cell communicationGO:00106472500.027
oocyte developmentGO:00485991240.026
response to other organismGO:00517072930.026
positive regulation of macromolecule biosynthetic processGO:00105572830.026
cell migrationGO:00164772380.026
cell proliferationGO:00082832990.026
regulation of response to stressGO:00801342000.026
positive regulation of signalingGO:00230562430.026
oocyte axis specificationGO:00073091080.025
head developmentGO:00603221350.025
Rat
antimicrobial humoral responseGO:0019730990.025
axis specificationGO:00097981670.025
regulation of nervous system developmentGO:00519602480.025
Rat
ameboidal type cell migrationGO:00016671510.025
defense responseGO:00069523000.025
neuron recognitionGO:00080381010.025
regulation of anatomical structure morphogenesisGO:00226032420.024
regulation of intracellular signal transductionGO:19025312360.024
cell adhesionGO:00071551360.024
Rat
carboxylic acid metabolic processGO:0019752920.024
developmental growthGO:00485892800.024
negative regulation of cell communicationGO:00106482230.024
phosphorylationGO:00163102940.024
response to abiotic stimulusGO:00096283410.024
gene silencingGO:00164581380.024
ion transmembrane transportGO:00342201220.024
regulation of protein metabolic processGO:00512462560.023
regulation of phosphate metabolic processGO:00192202100.023
localization of cellGO:00516742570.023
protein localizationGO:00081042840.023
cell recognitionGO:00080371020.023
extracellular matrix constituent secretionGO:007027840.023
posttranscriptional regulation of gene expressionGO:00106081450.023
cellular response to organic substanceGO:00713101320.023
nucleobase containing compound catabolic processGO:00346551650.023
anterior posterior axis specificationGO:00099481090.023
olfactory behaviorGO:0042048970.023
chromosome organizationGO:00512763600.023
o glycan processingGO:001626630.023
sensory perception of salty tasteGO:005091430.023
oocyte anterior posterior axis specificationGO:0007314720.022
locomotory behaviorGO:00076261760.022
regulation of cell cycleGO:00517262910.022
skeletal muscle organ developmentGO:0060538480.022
carbohydrate derivative biosynthetic processGO:1901137850.022
glycosyl compound catabolic processGO:19016581120.022
regulation of neuron differentiationGO:00456641030.022
mesenchymal cell developmentGO:001403110.022
tripartite regional subdivisionGO:00073511030.022
immune responseGO:00069552460.021
regulation of organ morphogenesisGO:2000027780.021
regulation of cell developmentGO:00602842150.021
oocyte differentiationGO:00099941450.021
anterior posterior axis specification embryoGO:00085951030.021
embryonic axis specificationGO:00005781070.021
endocytosisGO:00068973100.021
regulation of cellular amino acid metabolic processGO:000652100.021
small molecule metabolic processGO:00442813050.021
regulation of gene expression epigeneticGO:00400291280.020
limb morphogenesisGO:003510810.020
columnar cuboidal epithelial cell differentiationGO:00020652560.020
camera type eye developmentGO:004301040.020
salivary gland developmentGO:00074311620.020
regulation of catalytic activityGO:00507901850.020
spermatid differentiationGO:00485151140.020
body morphogenesisGO:001017120.020
single organism catabolic processGO:00447122280.020
telencephalon developmentGO:002153720.020
regulation of apoptotic processGO:00429811300.020
embryonic development via the syncytial blastodermGO:00017001480.020
circulatory system developmentGO:0072359820.020
macromolecule catabolic processGO:00090571610.020
ovarian follicle cell developmentGO:00307072480.019
actin filament based processGO:00300292200.019
multi organism behaviorGO:00517051750.019
gene silencing by rnaGO:0031047570.019
embryo development ending in birth or egg hatchingGO:00097921520.019
organelle fissionGO:00482853400.019
positive regulation of phosphorus metabolic processGO:00105621390.019
regulation of programmed cell deathGO:00430671520.019
dorsal ventral pattern formationGO:00099531330.019
notch signaling pathwayGO:00072191200.019
chemosensory behaviorGO:00076351060.019
proteolysisGO:00065081920.019
rrna processingGO:000636430.019
regulation of mrna splicing via spliceosomeGO:0048024640.018
posttranscriptional gene silencingGO:0016441460.018
regulation of epithelial cell proliferationGO:005067840.018
establishment or maintenance of cell polarityGO:00071631670.018
negative regulation of signal transductionGO:00099682060.018
regulation of immune responseGO:00507761180.018
regulation of cellular protein metabolic processGO:00322682430.018
hindbrain developmentGO:003090220.018
neurological system processGO:00508773580.018
phagocytosisGO:00069092150.018
germarium derived egg chamber formationGO:00072931010.018
wnt signaling pathwayGO:0016055980.017
regulation of cellular ketone metabolic processGO:001056530.017
establishment of organelle localizationGO:00516561220.017
retina development in camera type eyeGO:006004140.017
regulation of synapse structure and activityGO:00508031280.017
Rat
purine containing compound metabolic processGO:00725211550.017
muscle organ developmentGO:00075171270.017
regulation of transportGO:00510491810.017
enzyme linked receptor protein signaling pathwayGO:00071671790.017
rna processingGO:00063961470.017
organic substance transportGO:00717022570.017
aromatic compound catabolic processGO:00194391660.017
morphogenesis of a branching epitheliumGO:0061138450.017
endomembrane system organizationGO:00102561190.017
regulation of mrna processingGO:0050684710.017
inter male aggressive behaviorGO:0002121600.017
regulation of phosphorylationGO:00423251470.016
heterocycle catabolic processGO:00467001660.016
regulation of synapse organizationGO:00508071100.016
Rat
nucleoside phosphate catabolic processGO:19012921100.016
macromolecular complex assemblyGO:00650032560.016
stem cell developmentGO:0048864790.016
carbohydrate metabolic processGO:0005975820.016
limb developmentGO:006017310.016
peptide metabolic processGO:0006518800.016
positive regulation of intracellular signal transductionGO:19025331160.015
positive regulation of transportGO:0051050920.015
multicellular organismal reproductive behaviorGO:00330571100.015
mrna metabolic processGO:00160711240.015
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377730.015
detection of chemical stimulus involved in sensory perceptionGO:0050907750.015
negative regulation of cell deathGO:0060548810.015
nephron developmentGO:007200630.015
muscle structure developmentGO:00610612240.015
regulation of cell proliferationGO:00421271630.015
single organism behaviorGO:00447083910.015
cellular response to dna damage stimulusGO:00069742230.015
epidermal growth factor receptor signaling pathwayGO:0007173580.015
immune effector processGO:0002252980.015
kidney epithelium developmentGO:007207330.015
cell maturationGO:00484691440.015
mrna splicing via spliceosomeGO:0000398730.015
cellular response to chemical stimulusGO:00708871990.015
synaptic vesicle localizationGO:0097479530.015
vesicle organizationGO:0016050440.015
gland developmentGO:00487321910.014
regulation of cell morphogenesisGO:00226041630.014
posttranscriptional gene silencing by rnaGO:0035194450.014
amine metabolic processGO:0009308120.014
regulation of synaptic transmissionGO:0050804690.014
adult locomotory behaviorGO:0008344760.014
negative regulation of cell developmentGO:0010721620.014
secretionGO:00469031090.014
nucleobase containing small molecule metabolic processGO:00550861740.014
stem cell differentiationGO:00488631170.014
cellularizationGO:0007349900.014
exocrine system developmentGO:00352721620.014
developmental cell growthGO:0048588520.014
cellular nitrogen compound catabolic processGO:00442701650.014
defense response to bacteriumGO:00427421780.014
oxoacid metabolic processGO:00434361030.014
regulation of phosphorus metabolic processGO:00511742100.014
regulation of rna splicingGO:0043484690.014
endosomal transportGO:0016197440.014
synaptic target recognitionGO:0008039450.014
eggshell chorion assemblyGO:0007306660.014
regulation of immune effector processGO:0002697520.014
cellular amine metabolic processGO:0044106120.014
pigmentationGO:0043473750.014
purine ribonucleoside triphosphate catabolic processGO:00092071080.014
purine ribonucleotide metabolic processGO:00091501450.014
rhythmic processGO:00485111060.014
organic cyclic compound catabolic processGO:19013611680.014
intracellular receptor signaling pathwayGO:0030522190.013
cellular amide metabolic processGO:0043603800.013
regulation of cell deathGO:00109411730.013
actin cytoskeleton organizationGO:00300362060.013
spermatid developmentGO:0007286980.013
positive regulation of protein metabolic processGO:00512471280.013
ribonucleoside catabolic processGO:00424541120.013
metal ion transportGO:0030001740.013
positive regulation of cellular amino acid metabolic processGO:004576400.013
meiotic nuclear divisionGO:00071261510.013
cell divisionGO:00513012480.013
alternative mrna splicing via spliceosomeGO:0000380600.013
secretion by cellGO:00329401010.013
multi multicellular organism processGO:00447061230.013
innate immune responseGO:00450871440.013
modification dependent macromolecule catabolic processGO:0043632790.013
purine nucleoside triphosphate catabolic processGO:00091461080.013
rna splicing via transesterification reactionsGO:0000375730.013
regulation of immune system processGO:00026821760.013
purine nucleotide metabolic processGO:00061631460.013
olfactory learningGO:0008355560.013
regulation of mitotic cell cycleGO:00073461900.012
negative regulation of programmed cell deathGO:0043069720.012
cellular amino acid metabolic processGO:0006520610.012
establishment or maintenance of apical basal cell polarityGO:0035088340.012
protein modification by small protein conjugation or removalGO:00706471060.012
protein maturationGO:0051604710.012
connective tissue developmentGO:006144830.012
protein ubiquitinationGO:0016567700.012
regulation of alternative mrna splicing via spliceosomeGO:0000381600.012
cytoplasmic transportGO:00164821300.012
positive regulation of catabolic processGO:00098961050.012
developmental programmed cell deathGO:00106231380.012
r7 cell differentiationGO:0045466430.012
regulation of mrna metabolic processGO:1903311720.012
glycoprotein biosynthetic processGO:0009101410.012
wound healingGO:0042060750.012
extracellular matrix organizationGO:0030198320.012
organophosphate catabolic processGO:00464341120.012
pole plasm assemblyGO:0007315610.012
kidney developmentGO:000182230.012
nucleoside triphosphate catabolic processGO:00091431080.012
purine ribonucleoside catabolic processGO:00461301120.012
positive regulation of cellular amine metabolic processGO:003324000.012
matingGO:00076181200.012
male mating behaviorGO:0060179700.012
monocarboxylic acid transportGO:001571830.011
mesenchymal cell differentiationGO:004876210.011
response to oxygen containing compoundGO:19017002000.011
regulation of secretionGO:0051046440.011
glycosyl compound metabolic processGO:19016571270.011
motor neuron axon guidanceGO:0008045580.011
response to ethanolGO:0045471590.011
rna splicingGO:0008380830.011
organonitrogen compound catabolic processGO:19015651280.011
regulation of neurogenesisGO:00507671580.011
cellular ketone metabolic processGO:0042180240.011
meiotic cell cycleGO:00513211710.011
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092380.011
ras protein signal transductionGO:0007265880.011
response to nutrient levelsGO:00316671140.011
cell cell adhesion via plasma membrane adhesion moleculesGO:0098742260.011
Rat
regulation of cellular catabolic processGO:00313291570.011
response to lipopolysaccharideGO:003249640.011
protein modification by small protein conjugationGO:0032446790.011
organelle localizationGO:00516401480.011
dna metabolic processGO:00062592270.011
signal transduction by phosphorylationGO:00230141070.011
lipid metabolic processGO:00066291210.011
eggshell formationGO:00307031050.011
learningGO:0007612750.011
stem cell proliferationGO:0072089880.011
chaeta developmentGO:0022416970.011
salivary gland morphogenesisGO:00074351450.011
apoptotic processGO:00069151590.011
establishment of synaptic vesicle localizationGO:0097480500.011
gland morphogenesisGO:00226121450.011
positive regulation of multicellular organismal processGO:00512401430.010
Rat
erbb signaling pathwayGO:0038127580.010
behavioral response to ethanolGO:0048149490.010
modification dependent protein catabolic processGO:0019941780.010
extrinsic apoptotic signaling pathwayGO:009719110.010
organophosphate metabolic processGO:00196371950.010
carbohydrate derivative catabolic processGO:19011361180.010
regulation of cellular amine metabolic processGO:003323830.010
axon extensionGO:0048675320.010
regulation of molecular functionGO:00650092170.010
instar larval developmentGO:0002168550.010
inorganic ion transmembrane transportGO:0098660730.010
cytoplasm organizationGO:0007028640.010
regulation of axonogenesisGO:0050770320.010
mitotic spindle organizationGO:00070522200.010
response to monosaccharideGO:003428440.010
intracellular mrna localizationGO:0008298660.010
positive regulation of molecular functionGO:00440931360.010
tissue migrationGO:00901301550.010
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.010
regulation of gene silencingGO:0060968630.010
ribonucleotide metabolic processGO:00092591450.010
establishment of protein localizationGO:00451841630.010
ribonucleotide catabolic processGO:00092611090.010
regulation of defense responseGO:00313471020.010
morphogenesis of follicular epitheliumGO:0016333360.010
neutral lipid biosynthetic processGO:004646020.010
homophilic cell adhesion via plasma membrane adhesion moleculesGO:0007156180.010
protein phosphorylationGO:00064681690.010

Cirl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.036
nervous system diseaseDOID:86300.019
disease of cellular proliferationDOID:1456600.012
organ system cancerDOID:005068600.012
cancerDOID:16200.012