IMP: Integrative Multi-species Prediction

Drosophila melanogaster

74 known processes

Myd88 (Dmel_CG2078)

CG2078 gene product from transcript CG2078-RA

(Aliases: LD20892,CG2078,myd88,MYD88,DmMyd88,kra,dMyd88,dMyD88,DmMyD88,EP(2)2535,DMMYD88,MyD88,Dmel\CG2078,Myd88F,Kra)

Entrez: 35956
FLYBASE: FBgn0033402
UniProtKB: Q7K105

Process Predictions
Disease Predictions

Myd88 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

Filter by process size:

Biological process	GO term ID	Process size	Probability	Func Analog Org
humoral immune response	GO:0006959	117	0.984
immune system process	GO:0002376	347	0.980
immune response	GO:0006955	246	0.974
positive regulation of antifungal peptide biosynthetic process	GO:0006967	5	0.971
embryonic pattern specification	GO:0009880	174	0.944
regionalization	GO:0003002	416	0.943
regulation of antifungal peptide production	GO:0002788	6	0.930
regulation of biosynthetic process of antibacterial peptides active against gram positive bacteria	GO:0002816	3	0.923
antimicrobial humoral response	GO:0019730	99	0.900
axis specification	GO:0009798	167	0.868
response to biotic stimulus	GO:0009607	294	0.846
regulation of antifungal peptide biosynthetic process	GO:0002810	5	0.841
antifungal humoral response	GO:0019732	12	0.833
positive regulation of antifungal peptide production	GO:0002804	6	0.821
regulation of defense response to fungus	GO:1900150	6	0.815
antifungal peptide biosynthetic process	GO:0002783	5	0.808
segmentation	GO:0035282	207	0.799
blastoderm segmentation	GO:0007350	159	0.752
positive regulation of antimicrobial peptide biosynthetic process	GO:0002807	26	0.719
regulation of defense response to virus by host	GO:0050691	10	0.696
peptide metabolic process	GO:0006518	80	0.683
production of molecular mediator of immune response	GO:0002440	46	0.637
antibacterial humoral response	GO:0019731	44	0.635
defense response to bacterium	GO:0042742	178	0.632
defense response	GO:0006952	300	0.630
regulation of antibacterial peptide biosynthetic process	GO:0002808	22	0.622
regulation of immune effector process	GO:0002697	52	0.594
dorsal ventral axis specification	GO:0009950	66	0.586
embryonic morphogenesis	GO:0048598	206	0.577
embryonic development via the syncytial blastoderm	GO:0001700	148	0.577
regulation of antibacterial peptide production	GO:0002786	22	0.571
positive regulation of antimicrobial peptide production	GO:0002225	28	0.524
anterior posterior axis specification embryo	GO:0008595	103	0.519
antimicrobial peptide production	GO:0002775	46	0.508
cell division	GO:0051301	248	0.491
innate immune response	GO:0045087	144	0.489	Zebrafish Mouse
death	GO:0016265	284	0.487
response to other organism	GO:0051707	293	0.484
antifungal peptide production	GO:0002781	7	0.475
response to external biotic stimulus	GO:0043207	293	0.471
embryonic axis specification	GO:0000578	107	0.467
defense response to virus	GO:0051607	23	0.462
organonitrogen compound biosynthetic process	GO:1901566	117	0.449
embryo development ending in birth or egg hatching	GO:0009792	152	0.447
positive regulation of antibacterial peptide production	GO:0002803	20	0.436
regulation of immune system process	GO:0002682	176	0.429
regulation of humoral immune response	GO:0002920	51	0.422
negative regulation of cell cycle process	GO:0010948	109	0.394
positive regulation of cellular biosynthetic process	GO:0031328	316	0.385	Mouse
antibacterial peptide production	GO:0002778	22	0.381
positive regulation of response to biotic stimulus	GO:0002833	31	0.375
tube development	GO:0035295	244	0.370
periodic partitioning	GO:0007365	29	0.369
positive regulation of defense response to virus by host	GO:0002230	10	0.369
regulation of immune response	GO:0050776	118	0.368
immune effector process	GO:0002252	98	0.365
regulation of response to stress	GO:0080134	200	0.362
regulation of cellular amide metabolic process	GO:0034248	39	0.360
activation of innate immune response	GO:0002218	4	0.358	Zebrafish Mouse
regulation of antimicrobial peptide biosynthetic process	GO:0002805	38	0.351
regulation of cell cycle	GO:0051726	291	0.338
regulation of cell cycle g1 s phase transition	GO:1902806	23	0.337
regulation of transport	GO:0051049	181	0.329
tissue morphogenesis	GO:0048729	297	0.323
organ or tissue specific immune response	GO:0002251	10	0.322
organonitrogen compound metabolic process	GO:1901564	318	0.321
anterior posterior axis specification	GO:0009948	109	0.319
response to bacterium	GO:0009617	198	0.311
establishment of localization in cell	GO:0051649	402	0.311
negative regulation of cell cycle phase transition	GO:1901988	103	0.308
response to organic substance	GO:0010033	284	0.301	Human Zebrafish Mouse
cell proliferation	GO:0008283	299	0.296	Mouse
defense response to fungus	GO:0050832	48	0.296
regulation of antimicrobial humoral response	GO:0002759	50	0.287
dorsal ventral pattern formation	GO:0009953	133	0.280
neurological system process	GO:0050877	358	0.275
positive regulation of antimicrobial humoral response	GO:0002760	28	0.271
antibacterial peptide biosynthetic process	GO:0002780	22	0.270
regulation of localization	GO:0032879	275	0.269
phosphorylation	GO:0016310	294	0.269	Mouse
regulation of i kappab kinase nf kappab signaling	GO:0043122	2	0.265	Human Mouse
regulation of biosynthetic process of antibacterial peptides active against gram negative bacteria	GO:0002813	14	0.263
regulation of defense response	GO:0031347	102	0.259
digestive system development	GO:0055123	149	0.258
regulation of cell differentiation	GO:0045595	302	0.255
positive regulation of humoral immune response	GO:0002922	28	0.255
regulation of response to biotic stimulus	GO:0002831	63	0.254
regulation of antimicrobial peptide production	GO:0002784	44	0.253
regulation of multi organism process	GO:0043900	131	0.252
defense response to gram negative bacterium	GO:0050829	94	0.247
anterior posterior pattern specification	GO:0009952	136	0.241
melanization defense response	GO:0035006	45	0.239
defense response to other organism	GO:0098542	225	0.235
morphogenesis of embryonic epithelium	GO:0016331	94	0.230
cell maturation	GO:0048469	144	0.225
regulation of defense response to virus	GO:0050688	14	0.224
regulation of cell cycle phase transition	GO:1901987	130	0.216
tripartite regional subdivision	GO:0007351	103	0.215
intracellular signal transduction	GO:0035556	300	0.212	Human Mouse
positive regulation of biosynthetic process of antibacterial peptides active against gram negative bacteria	GO:0006964	12	0.203
regulation of innate immune response	GO:0045088	71	0.203	Zebrafish Mouse
segment polarity determination	GO:0007367	25	0.203
melanin metabolic process	GO:0006582	47	0.201
immune response activating signal transduction	GO:0002757	2	0.200	Mouse
negative regulation of signaling	GO:0023057	219	0.198
cell death	GO:0008219	279	0.194
cellular response to organic substance	GO:0071310	132	0.191	Mouse
actin cytoskeleton organization	GO:0030036	206	0.191
pattern recognition receptor signaling pathway	GO:0002221	2	0.190	Mouse
catabolic process	GO:0009056	409	0.189
positive regulation of multi organism process	GO:0043902	40	0.187
body morphogenesis	GO:0010171	2	0.186
positive regulation of phosphate metabolic process	GO:0045937	139	0.183	Mouse
actin filament based process	GO:0030029	220	0.178
post embryonic appendage morphogenesis	GO:0035120	385	0.177
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.174
cell cycle phase transition	GO:0044770	140	0.174
cognition	GO:0050890	141	0.173
cellular response to external stimulus	GO:0071496	66	0.171	Human
negative regulation of signal transduction	GO:0009968	206	0.170
positive regulation of signaling	GO:0023056	243	0.170	Human Mouse
macromolecular complex assembly	GO:0065003	256	0.170
vesicle mediated transport	GO:0016192	381	0.170
positive regulation of rna biosynthetic process	GO:1902680	266	0.168
kidney morphogenesis	GO:0060993	3	0.167
regulation of molecular function	GO:0065009	217	0.164	Mouse
positive regulation of biosynthetic process	GO:0009891	316	0.164	Mouse
positive regulation of signal transduction	GO:0009967	223	0.163	Human Mouse
phenol containing compound metabolic process	GO:0018958	57	0.163
purine ribonucleoside metabolic process	GO:0046128	127	0.160
single organism behavior	GO:0044708	391	0.156
antimicrobial peptide biosynthetic process	GO:0002777	38	0.156
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.156
g1 s transition of mitotic cell cycle	GO:0000082	31	0.155
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.155	Mouse
cellular response to abiotic stimulus	GO:0071214	58	0.152	Human
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.151
pigment metabolic process	GO:0042440	84	0.145
respiratory system development	GO:0060541	213	0.143
positive regulation of cell communication	GO:0010647	250	0.140	Human Mouse
regulation of defense response to bacterium	GO:1900424	30	0.140
negative regulation of cell communication	GO:0010648	223	0.140
stem cell proliferation	GO:0072089	88	0.138
regulation of production of molecular mediator of immune response	GO:0002700	44	0.138
positive regulation of response to stimulus	GO:0048584	323	0.135
positive regulation of immune system process	GO:0002684	68	0.134
response to fungus	GO:0009620	50	0.132
oocyte dorsal ventral axis specification	GO:0007310	34	0.129
regulation of catabolic process	GO:0009894	170	0.129
epithelial cell differentiation	GO:0030855	322	0.128	Mouse
amide biosynthetic process	GO:0043604	42	0.127
immune response regulating signaling pathway	GO:0002764	2	0.127	Mouse
apoptotic process	GO:0006915	159	0.127
response to starvation	GO:0042594	97	0.127
growth	GO:0040007	359	0.125	Mouse
imaginal disc derived appendage development	GO:0048737	399	0.125
retinal cell programmed cell death	GO:0046666	25	0.125
single organism catabolic process	GO:0044712	228	0.122
positive regulation of antibacterial peptide biosynthetic process	GO:0006963	20	0.121
negative regulation of cell cycle	GO:0045786	116	0.120
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.120
positive regulation of programmed cell death	GO:0043068	62	0.117
innate immune response activating signal transduction	GO:0002758	2	0.116	Mouse
negative regulation of cell cycle g1 s phase transition	GO:1902807	13	0.115
protein complex biogenesis	GO:0070271	201	0.115
muscle structure development	GO:0061061	224	0.110
regulation of cell cycle process	GO:0010564	181	0.110
protein complex assembly	GO:0006461	200	0.108
asymmetric cell division	GO:0008356	37	0.108
regulation of cell proliferation	GO:0042127	163	0.107	Mouse
positive regulation of immune response	GO:0050778	63	0.105
memory	GO:0007613	94	0.104
positive regulation of transcription dna templated	GO:0045893	266	0.104
positive regulation of immune effector process	GO:0002699	28	0.103
regulation of protein metabolic process	GO:0051246	256	0.102	Mouse
negative regulation of cellular metabolic process	GO:0031324	382	0.100
digestive tract development	GO:0048565	149	0.100
positive regulation of gene expression	GO:0010628	290	0.099
positive regulation of catabolic process	GO:0009896	105	0.099
morphogenesis of an epithelium	GO:0002009	276	0.098
transcription from rna polymerase ii promoter	GO:0006366	368	0.098
protein transport	GO:0015031	155	0.097
organelle fission	GO:0048285	340	0.096
organelle assembly	GO:0070925	198	0.096
mapk cascade	GO:0000165	107	0.096	Mouse
protein localization	GO:0008104	284	0.095
pole plasm mrna localization	GO:0019094	49	0.095
regulation of cellular response to stress	GO:0080135	89	0.095	Mouse
response to virus	GO:0009615	28	0.093	Mouse
pole plasm rna localization	GO:0007316	52	0.093
urogenital system development	GO:0001655	72	0.092
mitotic cell cycle phase transition	GO:0044772	138	0.092
cellular response to chemical stimulus	GO:0070887	199	0.092	Mouse
taxis	GO:0042330	304	0.091
myotube differentiation	GO:0014902	46	0.091
biosynthetic process of antibacterial peptides active against gram positive bacteria	GO:0002815	3	0.091
regulation of cell size	GO:0008361	63	0.091
nf kappab import into nucleus	GO:0042348	1	0.090
protein phosphorylation	GO:0006468	169	0.090
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.089
salivary gland development	GO:0007431	162	0.089
nucleoside metabolic process	GO:0009116	127	0.088
response to nutrient levels	GO:0031667	114	0.087
pole plasm assembly	GO:0007315	61	0.087
syncytium formation by plasma membrane fusion	GO:0000768	43	0.085
myoblast fusion	GO:0007520	43	0.084
defense response to gram positive bacterium	GO:0050830	41	0.084
positive regulation of cellular amide metabolic process	GO:0034250	26	0.084
regulation of cellular localization	GO:0060341	136	0.084
developmental maturation	GO:0021700	172	0.083
regulation of pole plasm oskar mrna localization	GO:0007317	27	0.083
autophagy	GO:0006914	108	0.082
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.082
positive regulation of melanization defense response	GO:0035008	1	0.082
regulation of multicellular organismal development	GO:2000026	414	0.081
neuromuscular junction development	GO:0007528	149	0.081
regulation of cell death	GO:0010941	173	0.080
positive regulation of hydrolase activity	GO:0051345	78	0.079
response to organic cyclic compound	GO:0014070	89	0.078
nucleotide metabolic process	GO:0009117	161	0.077
detection of stimulus involved in sensory perception	GO:0050906	92	0.075
secondary metabolic process	GO:0019748	75	0.074
positive regulation of cellular catabolic process	GO:0031331	95	0.073
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.073
response to extracellular stimulus	GO:0009991	116	0.072
regulation of cellular component biogenesis	GO:0044087	201	0.071
cellular response to nutrient levels	GO:0031669	62	0.071
nephron morphogenesis	GO:0072028	3	0.071
negative regulation of rna biosynthetic process	GO:1902679	240	0.071
regulation of programmed cell death	GO:0043067	152	0.071
synapse organization	GO:0050808	196	0.071
chemotaxis	GO:0006935	249	0.071
regulation of autophagy	GO:0010506	62	0.070
dendrite morphogenesis	GO:0048813	199	0.069
cellular catabolic process	GO:0044248	372	0.069
positive regulation of rna metabolic process	GO:0051254	271	0.069
extrinsic apoptotic signaling pathway	GO:0097191	1	0.069
positive regulation of protein metabolic process	GO:0051247	128	0.068	Mouse
ribonucleoside metabolic process	GO:0009119	127	0.068
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.068
regulation of mitotic cell cycle	GO:0007346	190	0.066
tube morphogenesis	GO:0035239	191	0.066
cellular response to starvation	GO:0009267	61	0.065
cellular amide metabolic process	GO:0043603	80	0.064
endocytosis	GO:0006897	310	0.064
cellular amino acid metabolic process	GO:0006520	61	0.064
organic substance catabolic process	GO:1901575	308	0.064
regulation of intracellular signal transduction	GO:1902531	236	0.063	Human Mouse
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.063
peptide biosynthetic process	GO:0043043	42	0.063
positive regulation of defense response	GO:0031349	59	0.063
wing disc morphogenesis	GO:0007472	344	0.063
mitotic spindle organization	GO:0007052	220	0.062
nuclear import	GO:0051170	51	0.062
secretion	GO:0046903	109	0.062
hematopoietic or lymphoid organ development	GO:0048534	57	0.062
eye development	GO:0001654	323	0.061
actin filament organization	GO:0007015	126	0.061
i kappab kinase nf kappab signaling	GO:0007249	6	0.061	Human Mouse
male gamete generation	GO:0048232	201	0.061
neuron projection guidance	GO:0097485	241	0.060
pole plasm protein localization	GO:0007318	10	0.059
regulation of cellular component size	GO:0032535	98	0.059
organic substance transport	GO:0071702	257	0.059
regulation of apoptotic process	GO:0042981	130	0.058
gtp catabolic process	GO:0006184	72	0.058
negative regulation of biosynthetic process	GO:0009890	277	0.058
nephron tubule morphogenesis	GO:0072078	3	0.058
negative regulation of cellular biosynthetic process	GO:0031327	277	0.057
rna processing	GO:0006396	147	0.057
negative regulation of multicellular organismal process	GO:0051241	142	0.056
striated muscle cell differentiation	GO:0051146	90	0.055
synaptic transmission	GO:0007268	288	0.055
multi organism behavior	GO:0051705	175	0.055
response to endogenous stimulus	GO:0009719	119	0.055	Mouse
regulation of cellular catabolic process	GO:0031329	157	0.055
positive regulation of cellular component biogenesis	GO:0044089	80	0.055
phagocytosis	GO:0006909	215	0.055
leg disc morphogenesis	GO:0007478	80	0.055
i kappab phosphorylation	GO:0007252	3	0.055
regulation of phosphate metabolic process	GO:0019220	210	0.054	Mouse
oocyte anterior posterior axis specification	GO:0007314	72	0.054
limb development	GO:0060173	1	0.054
stem cell differentiation	GO:0048863	117	0.053
response to radiation	GO:0009314	155	0.053
axonogenesis	GO:0007409	290	0.053
cellular protein modification process	GO:0006464	438	0.052
cytokinesis	GO:0000910	90	0.052
positive regulation of response to external stimulus	GO:0032103	44	0.052
melanotic encapsulation of foreign target	GO:0035011	30	0.052
long term memory	GO:0007616	62	0.052
response to oxygen containing compound	GO:1901700	200	0.052	Mouse
rna localization	GO:0006403	115	0.051
negative regulation of developmental process	GO:0051093	201	0.051
regulation of organelle organization	GO:0033043	196	0.051
negative regulation of response to stimulus	GO:0048585	258	0.050
regulation of protein localization	GO:0032880	76	0.050
gland morphogenesis	GO:0022612	145	0.050
positive regulation of intracellular signal transduction	GO:1902533	116	0.050	Human Mouse
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.050
positive regulation of developmental process	GO:0051094	143	0.050
appendage morphogenesis	GO:0035107	397	0.049
oxoacid metabolic process	GO:0043436	103	0.049
positive regulation of phosphorus metabolic process	GO:0010562	139	0.049	Mouse
regulation of response to external stimulus	GO:0032101	115	0.049
axon guidance	GO:0007411	233	0.049
hemocyte differentiation	GO:0042386	38	0.049
regulation of cytoskeleton organization	GO:0051493	89	0.048
response to wounding	GO:0009611	94	0.048	Mouse
regulation of cell substrate adhesion	GO:0010810	2	0.048
positive regulation of i kappab kinase nf kappab signaling	GO:0043123	1	0.048	Human Mouse
purine nucleotide catabolic process	GO:0006195	109	0.047
regulation of organ morphogenesis	GO:2000027	78	0.047
regulation of cellular protein metabolic process	GO:0032268	243	0.047
glycosyl compound metabolic process	GO:1901657	127	0.047
response to dsrna	GO:0043331	15	0.047
guanosine containing compound catabolic process	GO:1901069	74	0.047
macromolecule catabolic process	GO:0009057	161	0.047
camera type eye development	GO:0043010	4	0.047
stem cell maintenance	GO:0019827	67	0.047
kidney development	GO:0001822	3	0.047
carbohydrate derivative metabolic process	GO:1901135	217	0.046
oocyte differentiation	GO:0009994	145	0.046
imaginal disc derived wing morphogenesis	GO:0007476	337	0.046
nephron tubule development	GO:0072080	3	0.045
larval development	GO:0002164	104	0.044
negative regulation of immune system process	GO:0002683	50	0.043
mitotic nuclear division	GO:0007067	213	0.043
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.043
digestive tract morphogenesis	GO:0048546	127	0.043
mesoderm development	GO:0007498	78	0.043
positive regulation of catalytic activity	GO:0043085	118	0.043
dna integrity checkpoint	GO:0031570	81	0.042
positive regulation of multicellular organismal process	GO:0051240	143	0.042	Mouse
cellular response to extracellular stimulus	GO:0031668	64	0.042
cell cycle checkpoint	GO:0000075	95	0.042
nucleoside triphosphate catabolic process	GO:0009143	108	0.041
positive regulation of production of molecular mediator of immune response	GO:0002702	28	0.041
single organism intracellular transport	GO:1902582	207	0.041
nucleobase containing small molecule metabolic process	GO:0055086	174	0.041
cell junction organization	GO:0034330	57	0.041
negative regulation of mitotic cell cycle	GO:0045930	109	0.040
stem cell development	GO:0048864	79	0.040
nephron development	GO:0072006	3	0.040
sensory organ morphogenesis	GO:0090596	260	0.040
positive regulation of mapk cascade	GO:0043410	63	0.040	Mouse
chromosome segregation	GO:0007059	157	0.040
immune system development	GO:0002520	57	0.040
limb morphogenesis	GO:0035108	1	0.039
regulation of establishment of protein localization	GO:0070201	61	0.039
forebrain development	GO:0030900	2	0.038
necrotic cell death	GO:0070265	1	0.038
activation of cysteine type endopeptidase activity involved in apoptotic process	GO:0006919	16	0.038
small molecule metabolic process	GO:0044281	305	0.038
gastrulation	GO:0007369	70	0.037
positive regulation of autophagy	GO:0010508	21	0.037
ras protein signal transduction	GO:0007265	88	0.037
response to decreased oxygen levels	GO:0036293	58	0.037
programmed cell death	GO:0012501	257	0.037
appendage development	GO:0048736	401	0.037
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.037
regulation of anatomical structure size	GO:0090066	163	0.036
developmental programmed cell death	GO:0010623	138	0.036
negative regulation of mitotic cell cycle phase transition	GO:1901991	103	0.036
regulation of catalytic activity	GO:0050790	185	0.036
cellular macromolecule localization	GO:0070727	220	0.035
positive regulation of molecular function	GO:0044093	136	0.035	Mouse
cell growth	GO:0016049	108	0.035
cell cycle g1 s phase transition	GO:0044843	31	0.035
positive regulation of macromolecule metabolic process	GO:0010604	405	0.035	Mouse
single organism cellular localization	GO:1902580	180	0.035
protein localization to nucleus	GO:0034504	55	0.035
positive regulation of defense response to bacterium	GO:1900426	23	0.034
negative regulation of cell differentiation	GO:0045596	143	0.034
response to light stimulus	GO:0009416	124	0.034
maternal determination of anterior posterior axis embryo	GO:0008358	74	0.034
exocrine system development	GO:0035272	162	0.033
regulation of anatomical structure morphogenesis	GO:0022603	242	0.033
nephron epithelium development	GO:0072009	3	0.033
regulation of protein transport	GO:0051223	57	0.033
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.033
regulation of nf kappab import into nucleus	GO:0042345	1	0.033
intracellular transport	GO:0046907	228	0.033
single organism nuclear import	GO:1902593	51	0.033
protein modification process	GO:0036211	438	0.033
cellular response to mechanical stimulus	GO:0071260	2	0.033	Human
regulation of hydrolase activity	GO:0051336	97	0.033
regulation of cell development	GO:0060284	215	0.032
purine ribonucleotide metabolic process	GO:0009150	145	0.032
response to hypoxia	GO:0001666	53	0.032
carboxylic acid metabolic process	GO:0019752	92	0.032
negative regulation of cell death	GO:0060548	81	0.031
head development	GO:0060322	135	0.031
epithelial tube morphogenesis	GO:0060562	88	0.031
lipid modification	GO:0030258	24	0.031
gland development	GO:0048732	191	0.031
purine ribonucleotide catabolic process	GO:0009154	109	0.031
response to lipopolysaccharide	GO:0032496	4	0.031	Mouse
regulation of phosphorus metabolic process	GO:0051174	210	0.031	Mouse
gtp metabolic process	GO:0046039	72	0.031
purine nucleotide metabolic process	GO:0006163	146	0.031
oocyte development	GO:0048599	124	0.030
toll signaling pathway	GO:0008063	25	0.030
nucleocytoplasmic transport	GO:0006913	72	0.030
nuclear division	GO:0000280	332	0.030
purine nucleoside metabolic process	GO:0042278	127	0.030
purine containing compound metabolic process	GO:0072521	155	0.030
cuticle development	GO:0042335	86	0.030
gastrulation involving germ band extension	GO:0010004	36	0.030
organic acid metabolic process	GO:0006082	103	0.030
regulation of developmental growth	GO:0048638	174	0.029
dna repair	GO:0006281	54	0.029
renal system development	GO:0072001	72	0.029
organelle localization	GO:0051640	148	0.029
negative regulation of g1 s transition of mitotic cell cycle	GO:2000134	13	0.029
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.029
epithelial structure maintenance	GO:0010669	17	0.029
regulation of mapk cascade	GO:0043408	92	0.028	Mouse
renal tubule morphogenesis	GO:0061333	44	0.028
intracellular mrna localization	GO:0008298	66	0.028
mesenchymal cell differentiation	GO:0048762	1	0.028
regulation of cellular ketone metabolic process	GO:0010565	3	0.028
regulation of secretion	GO:0051046	44	0.028
compound eye development	GO:0048749	307	0.028
secretion by cell	GO:0032940	101	0.028
nucleotide catabolic process	GO:0009166	109	0.028
negative regulation of programmed cell death	GO:0043069	72	0.027
organophosphate metabolic process	GO:0019637	195	0.027
response to alcohol	GO:0097305	95	0.027
cellular component assembly involved in morphogenesis	GO:0010927	151	0.027
synapse assembly	GO:0007416	143	0.027
open tracheal system development	GO:0007424	204	0.027
response to oxidative stress	GO:0006979	86	0.027
positive regulation of biosynthetic process of antibacterial peptides active against gram positive bacteria	GO:0006965	3	0.027
positive regulation of cell migration	GO:0030335	2	0.026
cellular response to endogenous stimulus	GO:0071495	80	0.026
nucleoside triphosphate metabolic process	GO:0009141	120	0.026
cellular response to molecule of bacterial origin	GO:0071219	3	0.026	Mouse
response to abiotic stimulus	GO:0009628	341	0.026	Human
ribonucleotide metabolic process	GO:0009259	145	0.026
synaptic growth at neuromuscular junction	GO:0051124	119	0.026
hemopoiesis	GO:0030097	46	0.026
syncytium formation	GO:0006949	43	0.025
dendrite development	GO:0016358	204	0.025
positive regulation of cell proliferation	GO:0008284	47	0.025	Mouse
mitotic cytokinesis	GO:0000281	50	0.025
central nervous system development	GO:0007417	201	0.025
positive regulation of phosphorylation	GO:0042327	87	0.025	Mouse
regulation of intracellular transport	GO:0032386	64	0.025
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.025
purine ribonucleoside catabolic process	GO:0046130	112	0.025
response to inorganic substance	GO:0010035	44	0.025
carbohydrate derivative biosynthetic process	GO:1901137	85	0.025
protein maturation	GO:0051604	71	0.025
single organismal cell cell adhesion	GO:0016337	45	0.025
guanosine containing compound metabolic process	GO:1901068	74	0.024
positive regulation of apoptotic signaling pathway	GO:2001235	4	0.024
molting cycle chitin based cuticle	GO:0007591	56	0.024
protein secretion	GO:0009306	45	0.024
skeletal muscle fiber development	GO:0048741	3	0.024
cellular ketone metabolic process	GO:0042180	24	0.024
negative regulation of intracellular signal transduction	GO:1902532	57	0.024
regulation of g1 s transition of mitotic cell cycle	GO:2000045	23	0.024
kidney epithelium development	GO:0072073	3	0.024
regulation of myotube differentiation	GO:0010830	6	0.024
axon development	GO:0061564	297	0.024
epidermal cell differentiation	GO:0009913	51	0.024
eye morphogenesis	GO:0048592	260	0.023
leg disc development	GO:0035218	92	0.023
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.023
somatic stem cell maintenance	GO:0035019	14	0.023
membrane organization	GO:0061024	112	0.023
monovalent inorganic cation transport	GO:0015672	40	0.023
positive regulation of secretion	GO:0051047	22	0.023
zymogen activation	GO:0031638	20	0.023
positive regulation of cellular protein metabolic process	GO:0032270	118	0.023
positive regulation of innate immune response	GO:0045089	38	0.023	Zebrafish Mouse
establishment of organelle localization	GO:0051656	122	0.022
establishment of protein localization	GO:0045184	163	0.022
mucosal immune response	GO:0002385	10	0.022
cell cell junction organization	GO:0045216	55	0.022
response to temperature stimulus	GO:0009266	106	0.022
meiotic cytokinesis	GO:0033206	33	0.022
regulation of nucleocytoplasmic transport	GO:0046822	35	0.022
positive regulation of cell death	GO:0010942	69	0.022
meiotic cell cycle process	GO:1903046	132	0.022
neuron remodeling	GO:0016322	29	0.022
intracellular mrna localization involved in anterior posterior axis specification	GO:0060811	53	0.022
negative regulation of molecular function	GO:0044092	51	0.021
ribonucleoside catabolic process	GO:0042454	112	0.021
aging	GO:0007568	143	0.021
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	116	0.021
atp metabolic process	GO:0046034	49	0.021
muscle system process	GO:0003012	21	0.021
response to nitrogen compound	GO:1901698	90	0.021	Mouse
dna metabolic process	GO:0006259	227	0.021
rna splicing	GO:0008380	83	0.021

Myd88 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.033

Loading network...

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network