Drosophila melanogaster

104 known processes

Atg18 (Dmel_CG7986)

Autophagy-specific gene 18

(Aliases: ATG18,atg18,Dmel\CG7986,CG7986)

Atg18 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval midgut histolysisGO:0035069221.000
cellular response to starvationGO:0009267610.999
macroautophagyGO:0016236420.999
response to starvationGO:0042594970.999
positive regulation of autophagyGO:0010508210.998
cellular response to nutrient levelsGO:0031669620.998
larval midgut cell programmed cell deathGO:0035096190.997
cellular response to extracellular stimulusGO:0031668640.997
autophagyGO:00069141080.997
regulation of autophagyGO:0010506620.996
autophagic vacuole assemblyGO:000004520.989
organelle assemblyGO:00709251980.963
cellular response to external stimulusGO:0071496660.959
regulation of nurse cell apoptotic processGO:004547790.952
response to extracellular stimulusGO:00099911160.921
histolysisGO:00075591020.892
establishment of localization in cellGO:00516494020.890
Human
tissue deathGO:00162711020.881
developmental programmed cell deathGO:00106231380.877
cell deathGO:00082192790.872
negative regulation of phosphatidylinositol 3 kinase signalingGO:001406740.868
catabolic processGO:00090564090.862
regulation of catabolic processGO:00098941700.822
response to nutrient levelsGO:00316671140.795
deathGO:00162652840.775
cellular catabolic processGO:00442483720.768
positive regulation of response to extracellular stimulusGO:003210680.722
intracellular signal transductionGO:00355563000.670
regulation of cellular catabolic processGO:00313291570.649
positive regulation of nurse cell apoptotic processGO:004585050.645
lipid modificationGO:0030258240.612
regulation of response to biotic stimulusGO:0002831630.552
synapse organizationGO:00508081960.529
programmed cell deathGO:00125012570.498
single organism catabolic processGO:00447122280.494
vesicle mediated transportGO:00161923810.471
Human Worm
positive regulation of cellular catabolic processGO:0031331950.466
exocrine system developmentGO:00352721620.425
regulation of intracellular signal transductionGO:19025312360.394
appendage morphogenesisGO:00351073970.372
salivary gland histolysisGO:0035070880.365
phosphatidylinositol mediated signalingGO:004801540.346
protein modification processGO:00362114380.343
gland morphogenesisGO:00226121450.327
salivary gland morphogenesisGO:00074351450.308
positive regulation of catabolic processGO:00098961050.304
positive regulation of rna metabolic processGO:00512542710.290
organic substance transportGO:00717022570.277
positive regulation of response to stimulusGO:00485843230.272
lipid metabolic processGO:00066291210.271
Worm
positive regulation of signalingGO:00230562430.269
protein localizationGO:00081042840.268
regulation of defense response to virusGO:0050688140.260
negative regulation of response to stimulusGO:00485852580.257
defense response to other organismGO:00985422250.251
regulation of developmental growthGO:00486381740.244
biosynthetic process of antibacterial peptides active against gram negative bacteriaGO:0002812140.238
positive regulation of macroautophagyGO:001623980.238
synaptic transmissionGO:00072682880.231
cellular lipid metabolic processGO:0044255830.230
defense response to virusGO:0051607230.218
spindle assemblyGO:0051225800.210
phosphatidylinositol phosphorylationGO:0046854100.206
response to biotic stimulusGO:00096072940.196
regulation of multi organism processGO:00439001310.181
response to oxygen containing compoundGO:19017002000.180
phosphorylationGO:00163102940.179
synaptic growth at neuromuscular junctionGO:00511241190.176
phosphatidylinositol 3 kinase signalingGO:001406540.169
immune system processGO:00023763470.166
gland developmentGO:00487321910.165
organelle membrane fusionGO:0090174160.164
regulation of tor signalingGO:0032006210.163
positive regulation of transcription dna templatedGO:00458932660.160
positive regulation of growthGO:0045927750.158
regulation of synapse organizationGO:00508071100.155
regulation of response to external stimulusGO:00321011150.155
positive regulation of multicellular organismal processGO:00512401430.154
imaginal disc derived wing morphogenesisGO:00074763370.152
regulation of response to stressGO:00801342000.148
endocytosisGO:00068973100.142
Worm
cytoplasmic transportGO:00164821300.141
Human
regulation of macroautophagyGO:0016241150.132
cellular response to chemical stimulusGO:00708871990.131
Fly
synapse assemblyGO:00074161430.131
response to virusGO:0009615280.130
cellular protein modification processGO:00064644380.129
negative regulation of signalingGO:00230572190.124
positive regulation of macromolecule biosynthetic processGO:00105572830.123
autophagic cell deathGO:0048102830.121
regulation of growthGO:00400082330.114
organonitrogen compound metabolic processGO:19015643180.109
negative regulation of signal transductionGO:00099682060.108
regulation of protein metabolic processGO:00512462560.108
negative regulation of cell communicationGO:00106482230.106
antibacterial humoral responseGO:0019731440.106
salivary gland cell autophagic cell deathGO:0035071830.104
nurse cell apoptotic processGO:0045476170.101
response to abiotic stimulusGO:00096283410.100
neuromuscular synaptic transmissionGO:0007274670.098
agingGO:00075681430.098
Worm
apoptotic processGO:00069151590.096
nuclear divisionGO:00002803320.092
regulation of establishment of protein localizationGO:0070201610.091
immune responseGO:00069552460.089
negative regulation of intracellular signal transductionGO:1902532570.089
defense response to bacteriumGO:00427421780.089
regulation of cell cycleGO:00517262910.089
inositol lipid mediated signalingGO:004801740.088
positive regulation of gene expressionGO:00106282900.087
positive regulation of biosynthetic processGO:00098913160.086
response to bacteriumGO:00096171980.085
neuromuscular junction developmentGO:00075281490.081
multicellular organismal agingGO:00102591400.080
Worm
regulation of response to extracellular stimulusGO:0032104180.080
multicellular organism growthGO:0035264460.080
regulation of multicellular organism growthGO:0040014400.079
regulation of immune system processGO:00026821760.078
response to alcoholGO:0097305950.077
dorsal ventral pattern formationGO:00099531330.077
single organism biosynthetic processGO:00447112060.077
regulation of transcription from rna polymerase ii promoterGO:00063573780.076
regulation of cell sizeGO:0008361630.076
regulation of synapse structure and activityGO:00508031280.074
establishment of organelle localizationGO:00516561220.073
Human
regulation of cellular response to stressGO:0080135890.073
organelle fissionGO:00482853400.073
developmental growthGO:00485892800.073
positive regulation of rna biosynthetic processGO:19026802660.071
positive regulation of nucleobase containing compound metabolic processGO:00459353320.070
antimicrobial humoral responseGO:0019730990.069
dendrite developmentGO:00163582040.068
defense responseGO:00069523000.067
regulation of phosphorus metabolic processGO:00511742100.066
lipid biosynthetic processGO:0008610460.066
membrane fusionGO:0061025420.065
digestive tract developmentGO:00485651490.065
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.064
humoral immune responseGO:00069591170.063
interspecies interaction between organismsGO:0044419160.063
immune effector processGO:0002252980.062
positive regulation of nucleic acid templated transcriptionGO:19035082660.062
regulation of programmed cell deathGO:00430671520.062
imaginal disc derived appendage developmentGO:00487373990.062
positive regulation of cell communicationGO:00106472500.062
regulation of defense response to virus by hostGO:0050691100.062
positive regulation of cellular protein metabolic processGO:00322701180.061
positive regulation of cellular biosynthetic processGO:00313283160.059
regulation of response to nutrient levelsGO:0032107180.059
organophosphate metabolic processGO:00196371950.059
negative regulation of growthGO:0045926840.059
growthGO:00400073590.058
Worm
cell growthGO:00160491080.058
positive regulation of multicellular organism growthGO:0040018210.057
nitrogen compound transportGO:0071705850.057
positive regulation of reproductive processGO:200024370.057
single organism intracellular transportGO:19025822070.054
Human
regulation of localizationGO:00328792750.053
lipid phosphorylationGO:0046834110.053
adult behaviorGO:00305341370.053
positive regulation of cell sizeGO:0045793210.052
regulation of cellular localizationGO:00603411360.052
intracellular transportGO:00469072280.052
Human
regulation of organelle organizationGO:00330431960.051
protein processingGO:0016485680.051
regulation of proteolysisGO:0030162870.051
digestive system developmentGO:00551231490.050
imaginal disc derived appendage morphogenesisGO:00351143950.049
cellular response to dna damage stimulusGO:00069742230.049
response to external biotic stimulusGO:00432072930.048
regulation of antimicrobial humoral responseGO:0002759500.048
intracellular protein transportGO:00068861040.047
post embryonic appendage morphogenesisGO:00351203850.047
regulation of mapk cascadeGO:0043408920.047
cellular macromolecule localizationGO:00707272200.047
organic substance catabolic processGO:19015753080.046
Worm
positive regulation of nitrogen compound metabolic processGO:00511733540.046
spindle assembly involved in mitosisGO:0090307500.046
positive regulation of signal transductionGO:00099672230.046
vesicle localizationGO:0051648550.046
Human
glycerolipid metabolic processGO:0046486340.046
cellular component assembly involved in morphogenesisGO:00109271510.046
macromolecular complex assemblyGO:00650032560.045
positive regulation of response to external stimulusGO:0032103440.044
regulation of humoral immune responseGO:0002920510.044
positive regulation of cell deathGO:0010942690.044
appendage developmentGO:00487364010.043
regulation of cell deathGO:00109411730.043
autophagic vacuole fusionGO:0000046150.042
dendrite morphogenesisGO:00488131990.042
wing disc morphogenesisGO:00074723440.042
protein transportGO:00150311550.042
vacuole organizationGO:000703380.042
single organism membrane fusionGO:0044801420.042
regulation of biosynthetic process of antibacterial peptides active against gram negative bacteriaGO:0002813140.041
adult locomotory behaviorGO:0008344760.041
regulation of transportGO:00510491810.040
mitotic nuclear divisionGO:00070672130.039
determination of adult lifespanGO:00083401370.039
Worm
regulation of production of molecular mediator of immune responseGO:0002700440.038
response to organic substanceGO:00100332840.037
hemopoiesisGO:0030097460.037
embryonic development via the syncytial blastodermGO:00017001480.037
defense response to gram positive bacteriumGO:0050830410.037
regulation of reproductive processGO:2000241540.037
cellular protein localizationGO:00346131600.036
midgut developmentGO:0007494230.036
maintenance of locationGO:0051235730.036
salivary gland developmentGO:00074311620.036
macromolecule catabolic processGO:00090571610.035
Worm
cation transportGO:00068121100.035
innate immune responseGO:00450871440.035
striated muscle cell differentiationGO:0051146900.034
internal protein amino acid acetylationGO:0006475380.034
microtubule cytoskeleton organization involved in mitosisGO:1902850520.034
regulation of steroid metabolic processGO:001921820.034
regulation of mitotic cell cycleGO:00073461900.034
regulation of phosphate metabolic processGO:00192202100.034
membrane invaginationGO:0010324110.033
signal transduction in response to dna damageGO:004277030.033
larval developmentGO:00021641040.033
Worm
organelle localizationGO:00516401480.033
Human
regulation of cellular ketone metabolic processGO:001056530.033
regulation of synaptic growth at neuromuscular junctionGO:0008582890.033
mapk cascadeGO:00001651070.033
single organism behaviorGO:00447083910.032
positive regulation of programmed cell deathGO:0043068620.032
regulation of anatomical structure sizeGO:00900661630.032
regulation of immune responseGO:00507761180.032
protein ubiquitinationGO:0016567700.031
regulation of immune effector processGO:0002697520.031
vesicle fusionGO:0006906190.031
regulation of i kappab kinase nf kappab signalingGO:004312220.031
regulation of synapse assemblyGO:0051963940.031
carboxylic acid metabolic processGO:0019752920.030
ribonucleoside metabolic processGO:00091191270.029
positive regulation of developmental processGO:00510941430.029
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101180.028
membrane organizationGO:00610241120.028
positive regulation of defense response to virus by hostGO:0002230100.028
regulation of nf kappab import into nucleusGO:004234510.028
response to other organismGO:00517072930.028
positive regulation of developmental growthGO:0048639620.028
positive regulation of synapse assemblyGO:0051965290.028
response to temperature stimulusGO:00092661060.027
divalent inorganic cation transportGO:0072511300.027
pole cell formationGO:0007279190.027
response to hexoseGO:000974630.027
endomembrane system organizationGO:00102561190.026
regulation of cellular protein metabolic processGO:00322682430.026
defense response to gram negative bacteriumGO:0050829940.026
positive regulation of apoptotic processGO:0043065470.026
regulation of catalytic activityGO:00507901850.026
Worm
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.025
protein importGO:0017038550.025
symbiosis encompassing mutualism through parasitismGO:0044403160.025
dna damage checkpointGO:0000077780.025
telencephalon developmentGO:002153720.025
stress activated protein kinase signaling cascadeGO:0031098550.025
positive regulation of phosphate metabolic processGO:00459371390.025
nucleocytoplasmic transportGO:0006913720.024
apoptotic process involved in developmentGO:1902742200.024
skeletal muscle fiber developmentGO:004874130.024
stem cell differentiationGO:00488631170.024
ribosomal large subunit biogenesisGO:004227310.024
positive regulation of macromolecule metabolic processGO:00106044050.024
muscle structure developmentGO:00610612240.024
transcription from rna polymerase ii promoterGO:00063663680.024
regulation of cellular amine metabolic processGO:003323830.024
regulation of secretionGO:0051046440.024
regulation of transmembrane transportGO:0034762270.023
cellular nitrogen compound catabolic processGO:00442701650.023
positive regulation of protein metabolic processGO:00512471280.023
guanosine containing compound catabolic processGO:1901069740.023
establishment of protein localizationGO:00451841630.023
stress activated mapk cascadeGO:0051403520.023
regulation of phosphorylationGO:00423251470.022
regulation of anatomical structure morphogenesisGO:00226032420.022
response to nitrogen compoundGO:1901698900.022
protein maturationGO:0051604710.022
positive regulation of transportGO:0051050920.021
negative regulation of cell cycleGO:00457861160.021
rna processingGO:00063961470.021
posttranscriptional regulation of gene expressionGO:00106081450.021
mitochondrion degradationGO:000042280.021
regulation of phosphatidylinositol 3 kinase signalingGO:001406640.021
positive regulation of synaptic growth at neuromuscular junctionGO:0045887260.021
negative regulation of cell proliferationGO:0008285690.021
proteolysisGO:00065081920.021
tor signalingGO:0031929320.020
regulation of apoptotic processGO:00429811300.020
regulation of hemocyte proliferationGO:0035206370.020
positive regulation of jnk cascadeGO:0046330160.020
monocarboxylic acid transportGO:001571830.020
regulation of defense responseGO:00313471020.020
tube developmentGO:00352952440.019
cellular response to oxygen containing compoundGO:1901701790.019
cellular homeostasisGO:0019725800.019
translationGO:0006412690.019
establishment of rna localizationGO:0051236470.019
pigmentationGO:0043473750.019
glycerophospholipid metabolic processGO:0006650230.019
regulation of translationGO:0006417560.019
spindle organizationGO:00070512530.019
protein localization to organelleGO:0033365820.018
meiotic cell cycleGO:00513211710.018
camera type eye morphogenesisGO:004859320.018
production of molecular mediator of immune responseGO:0002440460.018
protein heterooligomerizationGO:005129140.018
muscle cell differentiationGO:00426921030.018
regulation of cell differentiationGO:00455953020.017
locomotory behaviorGO:00076261760.017
ion transportGO:00068111450.017
metal ion homeostasisGO:0055065440.017
regulation of myotube differentiationGO:001083060.017
regulation of jnk cascadeGO:0046328400.017
positive regulation of response to nutrient levelsGO:003210980.016
negative regulation of nervous system developmentGO:0051961920.016
determination of dorsal ventral asymmetryGO:004826230.016
protein catabolic processGO:00301631010.016
Worm
regulation of protein localizationGO:0032880760.016
terminal button organizationGO:0072553190.016
response to organophosphorusGO:004668320.016
organic hydroxy compound metabolic processGO:1901615830.016
regulation of stress activated mapk cascadeGO:0032872410.016
rna transportGO:0050658460.016
small molecule metabolic processGO:00442813050.016
cell agingGO:000756920.016
oocyte fate determinationGO:0030716270.016
fatty acid homeostasisGO:005508920.016
neuron remodelingGO:0016322290.016
regulation of stress activated protein kinase signaling cascadeGO:0070302420.016
purine nucleotide metabolic processGO:00061631460.016
regulation of cell cycle processGO:00105641810.016
regulation of cell growthGO:0001558430.015
regulation of cellular amino acid metabolic processGO:000652100.015
response to woundingGO:0009611940.015
response to organic cyclic compoundGO:0014070890.015
chemical homeostasisGO:0048878920.015
regulation of antimicrobial peptide productionGO:0002784440.015
regulation of cell proliferationGO:00421271630.015
epithelial cell differentiationGO:00308553220.015
regulation of lipid transportGO:003236830.015
regulation of protein catabolic processGO:0042176550.015
torc1 signalingGO:0038202120.015
regulation of synaptic transmissionGO:0050804690.015
viral life cycleGO:001905870.014
myotube cell developmentGO:001490430.014
nucleotide metabolic processGO:00091171610.014
guanosine containing compound metabolic processGO:1901068740.014
tube morphogenesisGO:00352391910.014
regulation of cell substrate adhesionGO:001081020.014
regulation of histone acetylationGO:003506570.014
antimicrobial peptide productionGO:0002775460.014
positive regulation of phosphorylationGO:0042327870.014
immune response activating signal transductionGO:000275720.014
cellular response to radiationGO:0071478520.014
nuclear transportGO:0051169720.014
response to ethanolGO:0045471590.014
response to insulinGO:0032868290.014
regulation of cell divisionGO:0051302720.014
rna phosphodiester bond hydrolysisGO:0090501170.014
protein kinase b signalingGO:004349110.013
asymmetric protein localization involved in cell fate determinationGO:004516790.013
cell proliferationGO:00082832990.013
regulation of nucleocytoplasmic transportGO:0046822350.013
regulation of small gtpase mediated signal transductionGO:0051056930.013
negative regulation of developmental growthGO:0048640640.013
heterocycle catabolic processGO:00467001660.013
reactive oxygen species metabolic processGO:0072593220.013
organic anion transportGO:0015711280.013
cell cycle checkpointGO:0000075950.013
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281250.013
jnk cascadeGO:0007254500.013
negative regulation of multicellular organismal processGO:00512411420.013
rrna processingGO:000636430.013
rna phosphodiester bond hydrolysis exonucleolyticGO:009050340.013
muscle organ developmentGO:00075171270.013
response to lipidGO:0033993380.012
purine ribonucleoside triphosphate metabolic processGO:00092051190.012
regulation of cellular component sizeGO:0032535980.012
dna metabolic processGO:00062592270.012
histone acetylationGO:0016573380.012
peptide transportGO:0015833100.012
nucleobase containing compound transportGO:0015931560.012
endosomal transportGO:0016197440.012
Human
peptidyl amino acid modificationGO:00181931050.012
negative regulation of intrinsic apoptotic signaling pathwayGO:200124310.012
regulation of molecular functionGO:00650092170.012
Worm
negative regulation of tor signalingGO:003200750.012
striated muscle cell developmentGO:0055002500.012
axonogenesisGO:00074092900.012
cellular amino acid metabolic processGO:0006520610.012
single organism cellular localizationGO:19025801800.012
body morphogenesisGO:001017120.012
gtp metabolic processGO:0046039720.012
positive regulation of antibacterial peptide biosynthetic processGO:0006963200.012
regulation of phosphatase activityGO:001092130.012
positive regulation of hydrolase activityGO:0051345780.011
Worm
larval salivary gland morphogenesisGO:0007436130.011
protein complex assemblyGO:00064612000.011
protein localization to nucleusGO:0034504550.011
nucleobase containing small molecule metabolic processGO:00550861740.011
phagocytosisGO:00069092150.011
Worm
neural retina developmentGO:000340740.011
developmental pigmentationGO:0048066680.011
organ or tissue specific immune responseGO:0002251100.011
positive regulation of bindingGO:005109940.011
multicellular organismal homeostasisGO:0048871410.011
positive regulation of peptidase activityGO:0010952290.011
negative regulation of synaptic growth at neuromuscular junctionGO:0045886390.011
histone h4 k16 acetylationGO:004398440.011
regulation of tube sizeGO:0035150460.011
positive regulation of translationGO:0045727120.011
melanin metabolic processGO:0006582470.011
regulation of nuclear divisionGO:0051783580.011
protein complex localizationGO:003150340.011
signal transduction by phosphorylationGO:00230141070.010
positive regulation of catalytic activityGO:00430851180.010
Worm
protein complex biogenesisGO:00702712010.010
organophosphate biosynthetic processGO:0090407460.010
mitotic spindle organizationGO:00070522200.010
axon developmentGO:00615642970.010
regulation of cell cycle phase transitionGO:19019871300.010
response to radiationGO:00093141550.010
negative regulation of cellular protein metabolic processGO:0032269850.010
phospholipid metabolic processGO:0006644230.010
melanization defense responseGO:0035006450.010
purine containing compound catabolic processGO:00725231120.010
positive regulation of proteolysisGO:0045862520.010

Atg18 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.020
disease of cellular proliferationDOID:1456600.012
cancerDOID:16200.012