Drosophila melanogaster

0 known processes

Hop (Dmel_CG2720)

Hsp70/Hsp90 organizing protein homolog

(Aliases: dSTI1,EP(2)0418,dhop,Dmel\CG2720,l(2)k00616,dmSTI1,CG2720,dHop,Sti1)

Hop biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
ovarian follicle cell migrationGO:00072971210.981
columnar cuboidal epithelial cell developmentGO:00020662490.958
negative regulation of developmental processGO:00510932010.954
digestive system developmentGO:00551231490.928
localization of cellGO:00516742570.915
eye developmentGO:00016543230.898
cell migrationGO:00164772380.865
germ line stem cell maintenanceGO:0030718500.846
cell motilityGO:00488702510.844
border follicle cell migrationGO:00072981130.832
establishment of localization in cellGO:00516494020.827
stem cell developmentGO:0048864790.806
stem cell differentiationGO:00488631170.792
compound eye developmentGO:00487493070.792
digestive tract developmentGO:00485651490.782
learning or memoryGO:00076111410.774
eye morphogenesisGO:00485922600.770
circadian rhythmGO:00076231050.754
establishment of tissue polarityGO:0007164870.752
hindgut morphogenesisGO:0007442580.730
photoreceptor cell differentiationGO:00465301700.717
epithelial cell developmentGO:00020642740.695
r3 r4 cell fate commitmentGO:0007464100.694
embryonic morphogenesisGO:00485982060.683
spermatogenesisGO:00072832000.670
tube morphogenesisGO:00352391910.668
hindgut developmentGO:0061525580.665
regulation of anatomical structure morphogenesisGO:00226032420.661
ovarian follicle cell developmentGO:00307072480.655
tube developmentGO:00352952440.653
single organismal cell cell adhesionGO:0016337450.650
response to abiotic stimulusGO:00096283410.635
epithelial cell migrationGO:00106311480.633
malpighian tubule morphogenesisGO:0007443440.632
cell adhesionGO:00071551360.586
stem cell maintenanceGO:0019827670.569
digestive tract morphogenesisGO:00485461270.567
compound eye photoreceptor cell differentiationGO:00017511400.549
tissue migrationGO:00901301550.530
compound eye photoreceptor fate commitmentGO:0001752360.525
male gamete generationGO:00482322010.500
single organism cell adhesionGO:0098602470.498
response to oxygen containing compoundGO:19017002000.484
actin filament based processGO:00300292200.482
regulation of secretionGO:0051046440.456
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.446
cellular response to endogenous stimulusGO:0071495800.443
cellular response to organic substanceGO:00713101320.422
eye photoreceptor cell developmentGO:0042462810.421
establishment of ommatidial planar polarityGO:0042067490.396
sensory organ morphogenesisGO:00905962600.396
eye photoreceptor cell fate commitmentGO:0042706370.386
central nervous system developmentGO:00074172010.369
regulation of anatomical structure sizeGO:00900661630.363
cell proliferationGO:00082832990.360
axis specificationGO:00097981670.355
regulation of response to stressGO:00801342000.351
regulation of imaginal disc derived wing sizeGO:0044719200.340
positive regulation of molecular functionGO:00440931360.327
protein modification processGO:00362114380.300
eggshell chorion assemblyGO:0007306660.298
establishment of planar polarityGO:0001736870.289
regulation of localizationGO:00328792750.288
muscle cell differentiationGO:00426921030.288
negative regulation of gene expressionGO:00106293870.287
regulation of cell differentiationGO:00455953020.287
gastrulation involving germ band extensionGO:0010004360.281
negative regulation of signalingGO:00230572190.272
apoptotic processGO:00069151590.272
cellular response to oxygen containing compoundGO:1901701790.266
positive regulation of signalingGO:00230562430.258
intracellular receptor signaling pathwayGO:0030522190.249
germ cell migrationGO:0008354430.244
intracellular signal transductionGO:00355563000.242
response to radiationGO:00093141550.238
morphogenesis of a polarized epitheliumGO:0001738930.230
columnar cuboidal epithelial cell differentiationGO:00020652560.222
cellular response to chemical stimulusGO:00708871990.220
immune system processGO:00023763470.214
head developmentGO:00603221350.212
antimicrobial humoral responseGO:0019730990.209
response to organic substanceGO:00100332840.209
response to lipopolysaccharideGO:003249640.204
spermatid differentiationGO:00485151140.198
segmentationGO:00352822070.195
eye photoreceptor cell differentiationGO:00017541450.191
catabolic processGO:00090564090.189
photoreceptor cell fate commitmentGO:0046552410.181
cellular response to organic cyclic compoundGO:0071407320.180
regulation of immune system processGO:00026821760.178
response to nutrient levelsGO:00316671140.177
positive regulation of nucleobase containing compound metabolic processGO:00459353320.173
hemocyte differentiationGO:0042386380.172
negative regulation of cell communicationGO:00106482230.170
response to organic cyclic compoundGO:0014070890.168
developmental growthGO:00485892800.167
regulation of transportGO:00510491810.162
cell junction assemblyGO:0034329420.161
immune responseGO:00069552460.159
regulation of growthGO:00400082330.159
epithelium migrationGO:00901321480.154
compound eye photoreceptor developmentGO:0042051780.151
growthGO:00400073590.149
response to alcoholGO:0097305950.149
regulation of organ morphogenesisGO:2000027780.149
taxisGO:00423303040.141
tissue morphogenesisGO:00487292970.140
biological adhesionGO:00226101380.140
response to woundingGO:0009611940.134
positive regulation of biosynthetic processGO:00098913160.131
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.129
transcription from rna polymerase ii promoterGO:00063663680.129
renal tubule morphogenesisGO:0061333440.127
circadian behaviorGO:0048512760.124
r3 r4 cell differentiationGO:0048056120.124
wound healingGO:0042060750.123
nuclear divisionGO:00002803320.122
brain developmentGO:00074201200.121
blastoderm segmentationGO:00073501590.120
cognitionGO:00508901410.120
cellular ketone metabolic processGO:0042180240.118
nucleocytoplasmic transportGO:0006913720.116
nuclear transportGO:0051169720.114
cell projection assemblyGO:0030031940.111
compound eye morphogenesisGO:00017452490.110
establishment or maintenance of cell polarityGO:00071631670.109
negative regulation of biosynthetic processGO:00098902770.108
ovarian follicle cell stalk formationGO:0030713170.107
embryonic hindgut morphogenesisGO:0048619480.107
muscle structure developmentGO:00610612240.106
negative regulation of multicellular organismal processGO:00512411420.106
rhythmic behaviorGO:0007622760.105
cellular catabolic processGO:00442483720.105
lipid metabolic processGO:00066291210.103
regulation of apoptotic processGO:00429811300.102
protein import into nucleusGO:0006606510.097
spermatid developmentGO:0007286980.096
cell junction organizationGO:0034330570.096
negative regulation of cell differentiationGO:00455961430.095
regulation of rac gtpase activityGO:003231410.095
cellular response to nitrogen compoundGO:1901699510.094
axonogenesisGO:00074092900.094
response to lipidGO:0033993380.092
intracellular transportGO:00469072280.091
embryonic development via the syncytial blastodermGO:00017001480.091
urogenital system developmentGO:0001655720.090
cellular response to hormone stimulusGO:0032870440.090
meiotic nuclear envelope disassemblyGO:005107820.086
dorsal appendage formationGO:0046843470.085
hematopoietic or lymphoid organ developmentGO:0048534570.083
branching morphogenesis of an epithelial tubeGO:0048754450.079
regulation of cell cycle processGO:00105641810.079
response to nitrogen compoundGO:1901698900.078
response to starvationGO:0042594970.078
cellular response to extracellular stimulusGO:0031668640.077
dna packagingGO:0006323910.077
negative regulation of transcription dna templatedGO:00458922370.076
convergent extension involved in gastrulationGO:006002720.075
positive regulation of cellular biosynthetic processGO:00313283160.073
positive regulation of response to stimulusGO:00485843230.073
lymph gland developmentGO:0048542280.072
dna conformation changeGO:00711031050.071
cell fate specificationGO:0001708710.071
negative regulation of gtpase activityGO:003426010.071
dna metabolic processGO:00062592270.070
gastrulationGO:0007369700.070
meiotic cell cycleGO:00513211710.069
positive regulation of cell developmentGO:0010720610.069
protein complex assemblyGO:00064612000.069
positive regulation of protein import into nucleus translocationGO:003316020.068
cellular amine metabolic processGO:0044106120.067
single organism catabolic processGO:00447122280.066
positive regulation of nitrogen compound metabolic processGO:00511733540.065
organic substance catabolic processGO:19015753080.065
positive regulation of signal transductionGO:00099672230.064
dendrite morphogenesisGO:00488131990.064
locomotory behaviorGO:00076261760.064
organic substance transportGO:00717022570.063
cellular response to nutrient levelsGO:0031669620.062
nuclear importGO:0051170510.062
morphogenesis of an epitheliumGO:00020092760.062
imaginal disc derived wing morphogenesisGO:00074763370.061
regulation of embryonic developmentGO:0045995680.060
single organism intracellular transportGO:19025822070.060
regulation of cell adhesionGO:0030155270.060
lipid biosynthetic processGO:0008610460.060
genitalia developmentGO:0048806260.058
regulation of intracellular signal transductionGO:19025312360.054
macromolecular complex assemblyGO:00650032560.053
ameboidal type cell migrationGO:00016671510.053
positive regulation of cell communicationGO:00106472500.052
regulation of cell shapeGO:00083601130.052
response to organonitrogen compoundGO:0010243750.052
regulation of cellular component movementGO:0051270420.051
negative regulation of nitrogen compound metabolic processGO:00511722650.051
regulation of programmed cell deathGO:00430671520.051
meiotic chromosome movement towards spindle poleGO:001634410.050
positive regulation of protein metabolic processGO:00512471280.050
embryonic pattern specificationGO:00098801740.049
multi organism behaviorGO:00517051750.049
actin filament organizationGO:00070151260.049
cell cell junction organizationGO:0045216550.049
cell deathGO:00082192790.048
hemopoiesisGO:0030097460.047
cellular response to lipidGO:0071396200.047
establishment of protein localizationGO:00451841630.047
single organism behaviorGO:00447083910.046
negative regulation of rna metabolic processGO:00512532510.046
regulation of cellular ketone metabolic processGO:001056530.046
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.045
regulation of molecular functionGO:00650092170.045
cation transportGO:00068121100.045
regulation of organelle organizationGO:00330431960.045
organelle inheritanceGO:004830820.044
locomotor rhythmGO:0045475560.044
positive regulation of rna biosynthetic processGO:19026802660.044
reproductive system developmentGO:0061458740.043
negative regulation of cell cycleGO:00457861160.042
cellular amino acid metabolic processGO:0006520610.042
response to hormoneGO:0009725450.042
cellular response to external stimulusGO:0071496660.042
positive regulation of protein kinase activityGO:0045860250.041
neurological system processGO:00508773580.041
axon developmentGO:00615642970.041
chemotaxisGO:00069352490.041
striated muscle cell developmentGO:0055002500.040
regulation of cellular localizationGO:00603411360.040
carboxylic acid metabolic processGO:0019752920.040
dorsal closure leading edge cell differentiationGO:004666320.040
convergent extensionGO:006002620.039
long term memoryGO:0007616620.039
dendrite regenerationGO:003110420.039
memoryGO:0007613940.039
reproductive structure developmentGO:0048608740.039
response to extracellular stimulusGO:00099911160.039
renal tubule developmentGO:0061326640.039
protein catabolic processGO:00301631010.038
photoreceptor cell developmentGO:0042461960.038
larval developmentGO:00021641040.038
protein complex biogenesisGO:00702712010.036
immune system developmentGO:0002520570.036
erbb signaling pathwayGO:0038127580.036
positive regulation of cell migrationGO:003033520.035
negative regulation of cellular protein metabolic processGO:0032269850.035
regulation of developmental growthGO:00486381740.034
single organism nuclear importGO:1902593510.034
jak stat cascadeGO:0007259490.033
regulation of viral genome replicationGO:004506940.033
epithelial cell differentiationGO:00308553220.033
muscle system processGO:0003012210.032
organelle fissionGO:00482853400.032
negative regulation of cellular metabolic processGO:00313243820.032
positive regulation of cysteine type endopeptidase activity involved in execution phase of apoptosisGO:200127240.032
p granule organizationGO:003071940.032
morphogenesis of a branching epitheliumGO:0061138450.031
single organism cellular localizationGO:19025801800.031
negative regulation of cell proliferationGO:0008285690.031
oocyte morphogenesisGO:004860130.031
cellular protein modification processGO:00064644380.029
positive regulation of cell differentiationGO:0045597640.029
response to other organismGO:00517072930.028
cellular response to organonitrogen compoundGO:0071417360.028
regulation of centriole replicationGO:004659920.028
peptide metabolic processGO:0006518800.028
response to external biotic stimulusGO:00432072930.028
regulation of transcription from rna polymerase ii promoterGO:00063573780.028
regulation of planar cell polarity pathway involved in axis elongationGO:200004020.028
positive regulation of intracellular signal transductionGO:19025331160.027
protein phosphorylationGO:00064681690.027
ribonucleoside catabolic processGO:00424541120.026
germarium derived egg chamber formationGO:00072931010.025
protein transportGO:00150311550.025
imaginal disc derived appendage morphogenesisGO:00351143950.025
cuticle developmentGO:0042335860.025
cellular protein catabolic processGO:0044257830.025
gland developmentGO:00487321910.024
positive regulation of nucleic acid templated transcriptionGO:19035082660.024
organic hydroxy compound metabolic processGO:1901615830.024
endomembrane system organizationGO:00102561190.024
anterior posterior axis specificationGO:00099481090.024
mushroom body developmentGO:0016319700.024
regulation of cell proliferation involved in compound eye morphogenesisGO:200049520.024
neuron projection guidanceGO:00974852410.023
malpighian tubule developmentGO:0072002640.023
regionalizationGO:00030024160.023
meiotic cell cycle processGO:19030461320.023
negative regulation of cellular component organizationGO:00511291080.023
hormone metabolic processGO:0042445330.022
morphogenesis of follicular epitheliumGO:0016333360.022
homeostatic processGO:00425921990.021
negative regulation of mitotic anaphase promoting complex activityGO:006056420.021
gastrulation with mouth forming firstGO:0001703360.021
larval lymph gland hemopoiesisGO:0035167170.021
innate immune responseGO:00450871440.021
establishment or maintenance of cytoskeleton polarityGO:0030952440.021
rho protein signal transductionGO:0007266140.020
imaginal disc growthGO:0007446370.020
activation of anaphase promoting complex activityGO:005148810.020
organonitrogen compound metabolic processGO:19015643180.020
positive regulation of rna metabolic processGO:00512542710.020
cellular component assembly involved in morphogenesisGO:00109271510.020
anterior posterior pattern specificationGO:00099521360.020
regulation of cell junction assemblyGO:190188820.020
regulation of centriole centriole cohesionGO:003099710.020
negative regulation of developmental pigmentationGO:004808610.020
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.019
maternal determination of dorsal ventral axis ovarian follicular epithelium soma encodedGO:000807110.019
regulation of nuclear divisionGO:0051783580.019
reproductive behaviorGO:00190981220.019
hematopoietic progenitor cell differentiationGO:000224410.019
striated muscle cell differentiationGO:0051146900.019
regulation of actin filament based processGO:0032970420.019
anterior head segmentationGO:003528830.019
regulation of protein phosphorylationGO:0001932640.019
imaginal disc derived appendage developmentGO:00487373990.019
post embryonic hemopoiesisGO:0035166170.019
regulation of actin cytoskeleton organizationGO:0032956420.018
establishment of cell polarityGO:0030010400.018
response to peptideGO:1901652290.018
cellular protein complex assemblyGO:0043623710.018
oocyte fate commitmentGO:004860020.018
establishment or maintenance of polarity of follicular epitheliumGO:0016334260.018
positive regulation of organelle organizationGO:0010638650.018
positive regulation of protein phosphorylationGO:0001934340.017
carbohydrate derivative metabolic processGO:19011352170.017
peptidyl amino acid modificationGO:00181931050.017
positive regulation of transportGO:0051050920.017
positive regulation of cell projection organizationGO:0031346290.017
regulation of cellular amino acid metabolic processGO:000652100.017
protein targeting to nucleusGO:0044744510.017
negative regulation of terminal cell fate specification open tracheal systemGO:003515520.017
regulation of cellular amine metabolic processGO:003323830.017
muscle tissue developmentGO:0060537300.017
small gtpase mediated signal transductionGO:0007264880.016
anterior posterior axis specification embryoGO:00085951030.016
humoral immune responseGO:00069591170.016
development of primary male sexual characteristicsGO:004654690.016
male sex differentiationGO:0046661250.016
small molecule metabolic processGO:00442813050.016
establishment or maintenance of epithelial cell apical basal polarityGO:0045197240.016
neuron fate commitmentGO:0048663500.016
secretionGO:00469031090.016
negative regulation of epithelial cell proliferationGO:005068040.016
negative regulation of ubiquitin protein ligase activity involved in mitotic cell cycleGO:005143620.016
wing disc morphogenesisGO:00074723440.016
positive regulation of macromolecule metabolic processGO:00106044050.016
nucleoside triphosphate metabolic processGO:00091411200.015
negative regulation of cellular biosynthetic processGO:00313272770.015
ion transportGO:00068111450.015
regulation of establishment of protein localizationGO:0070201610.015
olfactory behaviorGO:0042048970.015
negative regulation of apoptotic processGO:0043066630.015
gene silencingGO:00164581380.015
negative regulation of transcription from rna polymerase iii promoterGO:001648020.015
microtubule slidingGO:005101230.015
regulation of signal transduction by p53 class mediatorGO:190179610.015
positive regulation of transcription dna templatedGO:00458932660.015
cytoplasmic transportGO:00164821300.015
programmed cell deathGO:00125012570.015
amine metabolic processGO:0009308120.015
attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregationGO:005131610.015
activation of ral gtpase activityGO:003285910.015
rhythmic processGO:00485111060.015
regulation of rna export from nucleusGO:004683130.015
cellular response to peptide hormone stimulusGO:0071375280.015
posttranscriptional gene silencing by rnaGO:0035194450.015
positive regulation of gene expressionGO:00106282900.015
body morphogenesisGO:001017120.015
peptidyl threonine modificationGO:001821030.015
negative regulation of mrna 3 end processingGO:003144130.015
ovulation cycleGO:004269810.015
regulation of immune responseGO:00507761180.015
neuron recognitionGO:00080381010.014
negative regulation of nucleic acid templated transcriptionGO:19035072400.014
regulation of ran gtpase activityGO:003231610.014
regulation of cytoskeleton organizationGO:0051493890.014
cellular response to metal ionGO:007124860.014
cardiac muscle tissue developmentGO:004873890.014
regulation of jak stat cascadeGO:0046425430.014
regulation of hemocyte proliferationGO:0035206370.014
regulation of dna metabolic processGO:0051052340.014
negative regulation of mitotic cell cycleGO:00459301090.014
negative regulation of eye photoreceptor cell developmentGO:004248030.014
positive regulation of chromatin silencing at telomereGO:003194020.014
positive regulation of immune responseGO:0050778630.014
epithelial cell cell adhesionGO:009013660.014
chromatin assembly or disassemblyGO:0006333520.013
specification of segmental identity antennal segmentGO:000738320.013
response to ketoneGO:1901654340.013
activation of mapkk activityGO:000018640.013
establishment or maintenance of polarity of larval imaginal disc epitheliumGO:001633630.013
regulation of catabolic processGO:00098941700.013
positive regulation of immune system processGO:0002684680.013
negative regulation of signal transductionGO:00099682060.013
endoderm formationGO:000170630.013
negative regulation of dna templated transcription initiationGO:200014310.013
activation of protein kinase activityGO:0032147120.013
response to hypoxiaGO:0001666530.013
transmembrane transportGO:00550851390.013
positive regulation of transcription involved in g2 m transition of mitotic cell cycleGO:009028210.013
germ line cyst formationGO:0048134440.013
negative regulation of purine nucleotide catabolic processGO:003312210.013
regulation of protein kinase activityGO:0045859510.013
oocyte microtubule cytoskeleton polarizationGO:0008103220.013
organelle localizationGO:00516401480.013
epithelial cell proliferationGO:0050673150.013
protein destabilizationGO:003164820.013
non canonical wnt signaling pathwayGO:003556780.013
regulation of cell cycleGO:00517262910.013
negative regulation of sequence specific dna binding transcription factor activityGO:004343340.013
regulation of lipid metabolic processGO:0019216150.012
regulation of epithelial cell differentiationGO:003085640.012
negative regulation of response to stimulusGO:00485852580.012
regulation of vesicle mediated transportGO:0060627590.012
sex differentiationGO:0007548810.012
positive regulation of lipid metabolic processGO:004583440.012
response to molecule of bacterial originGO:000223770.012
cytoplasmic sequestering of nf kappabGO:000725310.012
positive regulation of epithelial cell differentiationGO:003085810.012
negative regulation of programmed cell deathGO:0043069720.012
meiotic dna repair synthesisGO:000071130.012
response to biotic stimulusGO:00096072940.012
neuromuscular synaptic transmissionGO:0007274670.012
negative regulation of ras gtpase activityGO:003426110.012
establishment of protein localization to organelleGO:0072594620.012
protein localization to nucleusGO:0034504550.012
actin cytoskeleton organizationGO:00300362060.012
regulation of protein serine threonine kinase activityGO:0071900250.012
deathGO:00162652840.012
dna templated transcriptional start site selectionGO:000117310.012
neuron maturationGO:0042551310.012
meiotic spindle checkpointGO:004477910.011
adherens junction organizationGO:0034332270.011
protein localizationGO:00081042840.011
oxoacid metabolic processGO:00434361030.011
cell fate determinationGO:0001709910.011
regulation of steroid metabolic processGO:001921820.011
open tracheal system developmentGO:00074242040.011
regulation of phosphorus metabolic processGO:00511742100.011
negative regulation of transcription initiation from rna polymerase ii promoterGO:006063310.011
maintenance of chromatin silencingGO:000634400.011
regulation of hematopoietic stem cell differentiationGO:190203610.011
morphogenesis of a branching structureGO:0001763450.011
asymmetric cell divisionGO:0008356370.011
muscle cell developmentGO:0055001500.011
response to metal ionGO:0010038230.011
regulation of humoral immune responseGO:0002920510.011
regulation of hemocyte differentiationGO:0045610220.010
negative regulation of nucleoside metabolic processGO:004597810.010
positive regulation of developmental growthGO:0048639620.010
regulation of synaptic transmissionGO:0050804690.010
metaphase anaphase transition of meiotic cell cycleGO:004478510.010
proteolysisGO:00065081920.010
regulation of cell deathGO:00109411730.010
oocyte anterior posterior axis specificationGO:0007314720.010
regulation of cell morphogenesisGO:00226041630.010
epithelial cell morphogenesisGO:0003382250.010
regulation of locomotionGO:0040012420.010
chaeta developmentGO:0022416970.010
regulation of embryonic cell shapeGO:0016476300.010
negative regulation of response to extracellular stimulusGO:003210560.010
oocyte constructionGO:00073081120.010

Hop disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.028
organ system cancerDOID:005068600.028
disease of cellular proliferationDOID:1456600.028
thyroid cancerDOID:178100.028
endocrine gland cancerDOID:17000.028
artery diseaseDOID:005082800.021
disease of anatomical entityDOID:700.021
cardiovascular system diseaseDOID:128700.021
aortic aneurysmDOID:362700.021
vascular diseaseDOID:17800.021
aortic diseaseDOID:52000.021
disease of metabolismDOID:001466700.012
intrinsic cardiomyopathyDOID:006003600.011
heart diseaseDOID:11400.011
muscular diseaseDOID:008000000.011
myopathyDOID:42300.011
musculoskeletal system diseaseDOID:1700.011
cardiomyopathyDOID:005070000.011
arrhythmogenic right ventricular cardiomyopathyDOID:005043100.011
muscle tissue diseaseDOID:6600.011