Drosophila melanogaster

37 known processes

emp (Dmel_CG2727)

epithelial membrane protein

(Aliases: Dmel\CG2727,CG2727)

emp biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to abiotic stimulusGO:00096283410.163
Fly
carboxylic acid metabolic processGO:0019752920.121
response to radiationGO:00093141550.090
Fly
lipid metabolic processGO:00066291210.081
Rat Fly
phagocytosisGO:00069092150.081
Human Rat
long chain fatty acid metabolic processGO:000167630.078
very long chain fatty acid metabolic processGO:000003840.076
organic acid metabolic processGO:00060821030.072
appendage morphogenesisGO:00351073970.063
cell deathGO:00082192790.063
cellular protein modification processGO:00064644380.061
regulation of hormone levelsGO:0010817400.061
Rat
very long chain fatty acid biosynthetic processGO:004276120.058
response to external biotic stimulusGO:00432072930.057
Human
organonitrogen compound metabolic processGO:19015643180.056
detection of stimulusGO:00516061560.056
Human Fly
appendage developmentGO:00487364010.055
single organism biosynthetic processGO:00447112060.051
Rat Fly
imaginal disc derived wing morphogenesisGO:00074763370.049
post embryonic appendage morphogenesisGO:00351203850.049
homeostatic processGO:00425921990.046
defense response to other organismGO:00985422250.046
negative regulation of gene expressionGO:00106293870.046
cellular lipid metabolic processGO:0044255830.045
Fly
organonitrogen compound biosynthetic processGO:19015661170.043
small molecule biosynthetic processGO:0044283370.042
ovarian follicle cell developmentGO:00307072480.042
regulation of protein metabolic processGO:00512462560.042
long chain fatty acid biosynthetic processGO:004275910.040
microtubule organizing center organizationGO:00310231680.040
vitamin metabolic processGO:000676620.039
regulation of cell deathGO:00109411730.038
tube morphogenesisGO:00352391910.038
immune system processGO:00023763470.036
Human
regulation of molecular functionGO:00650092170.035
Human
wing disc morphogenesisGO:00074723440.035
monocarboxylic acid metabolic processGO:0032787290.035
connective tissue developmentGO:006144830.034
regulation of cellular protein metabolic processGO:00322682430.034
neuron recognitionGO:00080381010.034
apoptotic processGO:00069151590.034
regulation of cell cycleGO:00517262910.034
regulation of localizationGO:00328792750.034
Human Rat
small molecule metabolic processGO:00442813050.033
regulation of catalytic activityGO:00507901850.032
Human
intracellular signal transductionGO:00355563000.032
response to bacteriumGO:00096171980.030
Human
positive regulation of response to stimulusGO:00485843230.030
Human
spindle organizationGO:00070512530.030
lipid biosynthetic processGO:0008610460.029
Rat
kidney developmentGO:000182230.029
detection of external stimulusGO:0009581660.027
Fly
mating behaviorGO:00076171060.027
cellular response to radiationGO:0071478520.027
Fly
protein modification processGO:00362114380.027
phosphorylationGO:00163102940.027
imaginal disc derived appendage morphogenesisGO:00351143950.027
fatty acid elongation unsaturated fatty acidGO:001936810.026
imaginal disc derived appendage developmentGO:00487373990.026
organic substance transportGO:00717022570.026
Human Rat Fly
single organism catabolic processGO:00447122280.026
neurological system processGO:00508773580.026
catabolic processGO:00090564090.026
secondary metabolite biosynthetic processGO:0044550240.025
regulation of multicellular organismal developmentGO:20000264140.025
cell proliferationGO:00082832990.025
open tracheal system developmentGO:00074242040.025
regulation of transportGO:00510491810.025
Rat
positive regulation of signal transductionGO:00099672230.024
response to biotic stimulusGO:00096072940.023
Human
organic substance catabolic processGO:19015753080.023
programmed cell deathGO:00125012570.023
phototransductionGO:0007602520.022
Fly
cellular catabolic processGO:00442483720.022
defense response to bacteriumGO:00427421780.021
oxoacid metabolic processGO:00434361030.021
endocytosisGO:00068973100.021
Human Rat Fly
deathGO:00162652840.021
negative regulation of response to stimulusGO:00485852580.021
regulation of intracellular signal transductionGO:19025312360.021
renal system developmentGO:0072001720.021
carboxylic acid biosynthetic processGO:0046394150.021
cellular response to chemical stimulusGO:00708871990.020
Human
response to other organismGO:00517072930.020
Human
cellular protein localizationGO:00346131600.020
chemical homeostasisGO:0048878920.020
negative regulation of cell deathGO:0060548810.020
ras protein signal transductionGO:0007265880.020
sensory organ morphogenesisGO:00905962600.020
cellular macromolecule localizationGO:00707272200.020
cell migrationGO:00164772380.020
response to organic substanceGO:00100332840.020
Human
vesicle mediated transportGO:00161923810.020
Human Rat Fly
lipid localizationGO:0010876540.020
Human Rat Fly
respiratory system developmentGO:00605412130.020
positive regulation of cell communicationGO:00106472500.020
spindle assemblyGO:0051225800.020
cell divisionGO:00513012480.020
positive regulation of macromolecule metabolic processGO:00106044050.019
secondary metabolic processGO:0019748750.019
synaptic target recognitionGO:0008039450.019
regulation of cell differentiationGO:00455953020.019
negative regulation of extracellular matrix disassemblyGO:001071610.019
columnar cuboidal epithelial cell differentiationGO:00020652560.019
organelle assemblyGO:00709251980.019
positive regulation of molecular functionGO:00440931360.019
Human
organelle fissionGO:00482853400.019
agingGO:00075681430.019
cell cell signaling involved in cell fate commitmentGO:00451682100.018
epithelial cell differentiationGO:00308553220.018
positive regulation of multicellular organismal processGO:00512401430.018
meiotic nuclear divisionGO:00071261510.018
macromolecular complex assemblyGO:00650032560.018
regulation of cell developmentGO:00602842150.017
defense responseGO:00069523000.017
regulation of programmed cell deathGO:00430671520.017
rhodopsin metabolic processGO:0046154100.017
Fly
single organism cellular localizationGO:19025801800.017
response to oxygen containing compoundGO:19017002000.017
Human
cell motilityGO:00488702510.017
mesoderm developmentGO:0007498780.017
eye morphogenesisGO:00485922600.017
response to extracellular stimulusGO:00099911160.017
regulation of transcription from rna polymerase ii promoterGO:00063573780.017
actin cytoskeleton organizationGO:00300362060.017
regulation of phosphorus metabolic processGO:00511742100.017
negative regulation of cellular metabolic processGO:00313243820.017
epithelium migrationGO:00901321480.016
centrosome organizationGO:00512971630.016
positive regulation of signalingGO:00230562430.016
sterol homeostasisGO:005509240.016
actin filament based processGO:00300292200.016
matingGO:00076181200.016
biological adhesionGO:00226101380.016
Human
segmentationGO:00352822070.016
fatty acid elongationGO:003049730.016
meiotic cell cycleGO:00513211710.016
regulation of mitotic cell cycleGO:00073461900.015
regionalizationGO:00030024160.015
defense response to gram negative bacteriumGO:0050829940.015
nuclear divisionGO:00002803320.015
ovarian follicle cell migrationGO:00072971210.015
response to reactive oxygen speciesGO:0000302240.015
single organism intracellular transportGO:19025822070.015
protein phosphorylationGO:00064681690.015
aromatic compound catabolic processGO:00194391660.015
regulation of hydrolase activityGO:0051336970.015
regulation of tube architecture open tracheal systemGO:0035152680.015
taxisGO:00423303040.015
Fly
negative regulation of nitrogen compound metabolic processGO:00511722650.015
positive regulation of phosphorus metabolic processGO:00105621390.015
epithelial cell developmentGO:00020642740.015
regulation of apoptotic processGO:00429811300.014
maintenance of locationGO:0051235730.014
Human
negative regulation of cell communicationGO:00106482230.014
axonogenesisGO:00074092900.014
response to nutrient levelsGO:00316671140.014
organic acid biosynthetic processGO:0016053150.014
negative regulation of cell cycle phase transitionGO:19019881030.014
response to ionizing radiationGO:0010212320.014
heart developmentGO:0007507820.014
cellular amine metabolic processGO:0044106120.014
body morphogenesisGO:001017120.014
response to lipopolysaccharideGO:003249640.014
Human
response to oxidative stressGO:0006979860.014
organonitrogen compound catabolic processGO:19015651280.013
tissue migrationGO:00901301550.013
axis specificationGO:00097981670.013
detection of abiotic stimulusGO:0009582660.013
Fly
regulation of neuron differentiationGO:00456641030.013
cellular response to abiotic stimulusGO:0071214580.013
Fly
tissue morphogenesisGO:00487292970.013
camera type eye developmentGO:004301040.013
xenobiotic catabolic processGO:004217810.013
posttranscriptional regulation of gene expressionGO:00106081450.013
regulation of intracellular transportGO:0032386640.013
synaptic transmissionGO:00072682880.013
regulation of nervous system developmentGO:00519602480.013
male gamete generationGO:00482322010.013
transcription from rna polymerase ii promoterGO:00063663680.013
cytoskeleton dependent cytokinesisGO:0061640810.013
stem cell differentiationGO:00488631170.013
amine metabolic processGO:0009308120.013
lateral inhibitionGO:00463312060.013
neuron projection guidanceGO:00974852410.012
regulation of phosphate metabolic processGO:00192202100.012
cellular amino acid metabolic processGO:0006520610.012
tube formationGO:0035148210.012
positive regulation of cellular protein metabolic processGO:00322701180.012
fatty acid metabolic processGO:0006631200.012
positive regulation of phosphate metabolic processGO:00459371390.012
negative regulation of protein metabolic processGO:0051248850.012
regulation of response to stressGO:00801342000.012
Human
protein localizationGO:00081042840.012
forebrain developmentGO:003090020.012
immune effector processGO:0002252980.012
reproductive behaviorGO:00190981220.012
compound eye morphogenesisGO:00017452490.012
cytokinesisGO:0000910900.012
response to organophosphorusGO:004668320.012
positive regulation of protein metabolic processGO:00512471280.012
negative regulation of extracellular matrix organizationGO:190305410.012
cell recognitionGO:00080371020.012
Human Rat
protein complex assemblyGO:00064612000.012
multi organism reproductive behaviorGO:00447051210.012
gland developmentGO:00487321910.012
cellular response to dna damage stimulusGO:00069742230.012
regulation of defense responseGO:00313471020.011
Human
positive regulation of lipid storageGO:001088440.011
Human
skin developmentGO:0043588650.011
positive regulation of catalytic activityGO:00430851180.011
Human
axon developmentGO:00615642970.011
antimicrobial humoral responseGO:0019730990.011
pigmentationGO:0043473750.011
Fly
carbohydrate derivative metabolic processGO:19011352170.011
hematopoietic progenitor cell differentiationGO:000224410.011
androgen metabolic processGO:000820910.011
Rat
response to glucoseGO:000974920.011
negative regulation of rna metabolic processGO:00512532510.011
small gtpase mediated signal transductionGO:0007264880.011
cellular ketone metabolic processGO:0042180240.011
protein localization to organelleGO:0033365820.011
response to alcoholGO:0097305950.011
protein complex biogenesisGO:00702712010.011
positive regulation of phosphorylationGO:0042327870.011
regulation of cellular component biogenesisGO:00440872010.011
cell adhesionGO:00071551360.011
epithelial cell migrationGO:00106311480.010
regulation of cellular ketone metabolic processGO:001056530.010
negative regulation of mitotic cell cycleGO:00459301090.010
eye developmentGO:00016543230.010
cytoplasmic transportGO:00164821300.010
spermatogenesisGO:00072832000.010
localization of cellGO:00516742570.010
positive regulation of cellular biosynthetic processGO:00313283160.010
regulation of neurogenesisGO:00507671580.010
synapse assemblyGO:00074161430.010
cellular nitrogen compound catabolic processGO:00442701650.010
regulation of proteolysisGO:0030162870.010
blastoderm segmentationGO:00073501590.010
regulation of cellular catabolic processGO:00313291570.010
ribonucleotide catabolic processGO:00092611090.010
negative regulation of developmental processGO:00510932010.010
negative regulation of mitotic cell cycle phase transitionGO:19019911030.010

emp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.129
nervous system diseaseDOID:86300.041
sensory system diseaseDOID:005015500.015
eye diseaseDOID:561400.015
eye and adnexa diseaseDOID:149200.015
musculoskeletal system diseaseDOID:1700.013
neurodegenerative diseaseDOID:128900.011
central nervous system diseaseDOID:33100.011