Drosophila melanogaster

44 known processes

spirit (Dmel_CG2056)

Serine Protease Immune Response Integrator

(Aliases: c-SP33,SP33,Dmel\CG2056,CG2056)

spirit biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to external biotic stimulusGO:00432072930.396
response to biotic stimulusGO:00096072940.383
immune system processGO:00023763470.317
regulation of biosynthetic process of antibacterial peptides active against gram positive bacteriaGO:000281630.314
response to bacteriumGO:00096171980.284
defense responseGO:00069523000.274
response to other organismGO:00517072930.258
defense response to other organismGO:00985422250.232
defense response to bacteriumGO:00427421780.209
immune responseGO:00069552460.205
negative regulation of peptidoglycan recognition protein signaling pathwayGO:006106030.169
activation of innate immune responseGO:000221840.140
biosynthetic process of antibacterial peptides active against gram positive bacteriaGO:000281530.134
innate immune response activating signal transductionGO:000275820.122
humoral immune responseGO:00069591170.121
pattern recognition receptor signaling pathwayGO:000222120.119
innate immune responseGO:00450871440.114
regulation of peptidoglycan recognition protein signaling pathwayGO:006105840.112
secondary metabolic processGO:0019748750.107
antibacterial humoral responseGO:0019731440.105
cytolysis in other organismGO:005171510.104
defense response to gram negative bacteriumGO:0050829940.102
antimicrobial humoral responseGO:0019730990.101
antifungal humoral responseGO:0019732120.094
positive regulation of response to stimulusGO:00485843230.085
positive regulation of biosynthetic process of antibacterial peptides active against gram positive bacteriaGO:000696530.085
defense response to gram positive bacteriumGO:0050830410.083
immune response activating signal transductionGO:000275720.080
regulation of multi organism processGO:00439001310.079
peptidoglycan recognition protein signaling pathwayGO:0061057160.079
killing of cells of other organismGO:003164010.071
antimicrobial peptide productionGO:0002775460.070
regulation of defense responseGO:00313471020.069
antibacterial peptide biosynthetic processGO:0002780220.069
regulation of defense response to bacteriumGO:1900424300.066
organonitrogen compound metabolic processGO:19015643180.061
regulation of response to stressGO:00801342000.060
defense response to fungusGO:0050832480.059
vesicle mediated transportGO:00161923810.057
biosynthetic process of antibacterial peptides active against gram negative bacteriaGO:0002812140.055
immune response regulating signaling pathwayGO:000276420.055
glycosaminoglycan catabolic processGO:000602730.054
lipopolysaccharide mediated signaling pathwayGO:003166310.053
response to lipopolysaccharideGO:003249640.053
melanization defense responseGO:0035006450.052
regionalizationGO:00030024160.050
intracellular signal transductionGO:00355563000.050
antimicrobial peptide biosynthetic processGO:0002777380.048
endocytosisGO:00068973100.048
negative regulation of cellular metabolic processGO:00313243820.047
response to peptidoglycanGO:003249420.047
negative regulation of defense response to bacteriumGO:190042570.047
regulation of antimicrobial peptide biosynthetic processGO:0002805380.047
regulation of response to biotic stimulusGO:0002831630.046
antibacterial peptide productionGO:0002778220.045
regulation of immune responseGO:00507761180.045
peptide metabolic processGO:0006518800.045
regulation of innate immune responseGO:0045088710.045
production of molecular mediator of immune responseGO:0002440460.044
response to woundingGO:0009611940.044
appendage morphogenesisGO:00351073970.044
positive regulation of antimicrobial peptide biosynthetic processGO:0002807260.044
regulation of antibacterial peptide productionGO:0002786220.044
amide biosynthetic processGO:0043604420.043
regulation of response to external stimulusGO:00321011150.043
negative regulation of response to stimulusGO:00485852580.043
immune effector processGO:0002252980.043
regulation of immune system processGO:00026821760.042
regulation of biosynthetic process of antibacterial peptides active against gram negative bacteriaGO:0002813140.041
positive regulation of cellular biosynthetic processGO:00313283160.041
positive regulation of defense responseGO:0031349590.041
positive regulation of nitrogen compound metabolic processGO:00511733540.041
cellular amide metabolic processGO:0043603800.040
regulation of humoral immune responseGO:0002920510.039
positive regulation of antibacterial peptide productionGO:0002803200.039
regulation of intracellular signal transductionGO:19025312360.039
appendage developmentGO:00487364010.039
post embryonic appendage morphogenesisGO:00351203850.039
wing disc morphogenesisGO:00074723440.039
pigment metabolic processGO:0042440840.039
phosphorylationGO:00163102940.038
negative regulation of immune system processGO:0002683500.038
positive regulation of signal transductionGO:00099672230.037
phagocytosisGO:00069092150.037
positive regulation of signalingGO:00230562430.037
imaginal disc derived wing morphogenesisGO:00074763370.037
defense response to virusGO:0051607230.036
positive regulation of antibacterial peptide biosynthetic processGO:0006963200.036
imaginal disc derived appendage morphogenesisGO:00351143950.036
positive regulation of biosynthetic process of antibacterial peptides active against gram negative bacteriaGO:0006964120.035
catabolic processGO:00090564090.035
regulation of antibacterial peptide biosynthetic processGO:0002808220.035
positive regulation of melanization defense responseGO:003500810.035
melanin metabolic processGO:0006582470.035
positive regulation of biosynthetic processGO:00098913160.035
positive regulation of cell communicationGO:00106472500.035
imaginal disc derived appendage developmentGO:00487373990.035
cellular response to lipopolysaccharideGO:007122230.034
organic substance catabolic processGO:19015753080.034
cellular catabolic processGO:00442483720.034
cellular response to molecule of bacterial originGO:007121930.033
positive regulation of response to biotic stimulusGO:0002833310.033
small molecule metabolic processGO:00442813050.033
peptidoglycan metabolic processGO:000027030.033
axis specificationGO:00097981670.032
regulation of cellular amide metabolic processGO:0034248390.032
negative regulation of signal transductionGO:00099682060.032
regulation of antimicrobial humoral responseGO:0002759500.031
response to organic substanceGO:00100332840.030
regulation of immune effector processGO:0002697520.030
positive regulation of defense response to bacteriumGO:1900426230.030
negative regulation of cell communicationGO:00106482230.029
body morphogenesisGO:001017120.029
dorsal ventral axis specificationGO:0009950660.029
carbohydrate derivative metabolic processGO:19011352170.029
carboxylic acid metabolic processGO:0019752920.029
single organism biosynthetic processGO:00447112060.029
response to abiotic stimulusGO:00096283410.028
protein modification processGO:00362114380.028
proteolysisGO:00065081920.028
positive regulation of immune system processGO:0002684680.028
positive regulation of antimicrobial humoral responseGO:0002760280.028
response to fungusGO:0009620500.027
regulation of antimicrobial peptide productionGO:0002784440.027
positive regulation of response to external stimulusGO:0032103440.027
positive regulation of cell migrationGO:003033520.027
lateral inhibitionGO:00463312060.027
negative regulation of gene expressionGO:00106293870.026
organelle fissionGO:00482853400.026
positive regulation of humoral immune responseGO:0002922280.026
negative regulation of nitrogen compound metabolic processGO:00511722650.026
positive regulation of production of molecular mediator of immune responseGO:0002702280.026
cellular protein modification processGO:00064644380.026
organonitrogen compound biosynthetic processGO:19015661170.026
regulation of mapk cascadeGO:0043408920.025
positive regulation of antimicrobial peptide productionGO:0002225280.025
response to oxygen containing compoundGO:19017002000.025
growthGO:00400073590.025
organic acid metabolic processGO:00060821030.025
camera type eye developmentGO:004301040.025
macromolecule catabolic processGO:00090571610.025
toll signaling pathwayGO:0008063250.025
organic hydroxy compound metabolic processGO:1901615830.024
negative regulation of signalingGO:00230572190.024
positive regulation of cellular amide metabolic processGO:0034250260.024
dorsal ventral pattern formationGO:00099531330.024
positive regulation of macromolecule metabolic processGO:00106044050.024
oxoacid metabolic processGO:00434361030.024
regulation of phosphorus metabolic processGO:00511742100.023
response to nitrogen compoundGO:1901698900.023
positive regulation of immune responseGO:0050778630.023
regulation of phosphate metabolic processGO:00192202100.023
peptidoglycan catabolic processGO:000925330.023
regulation of secondary metabolic processGO:004345570.023
regulation of cellular response to stressGO:0080135890.023
regulation of multicellular organismal developmentGO:20000264140.022
stress activated mapk cascadeGO:0051403520.022
peptide biosynthetic processGO:0043043420.022
positive regulation of gene expressionGO:00106282900.022
forebrain developmentGO:003090020.022
positive regulation of nucleobase containing compound metabolic processGO:00459353320.022
segmentationGO:00352822070.022
regulation of cell cycleGO:00517262910.022
signal transduction by phosphorylationGO:00230141070.022
regulation of production of molecular mediator of immune responseGO:0002700440.022
embryonic pattern specificationGO:00098801740.022
response to endogenous stimulusGO:00097191190.022
negative regulation of cellular biosynthetic processGO:00313272770.022
actin filament based processGO:00300292200.022
blastoderm segmentationGO:00073501590.021
positive regulation of macromolecule biosynthetic processGO:00105572830.021
limb developmentGO:006017310.021
cell cell signaling involved in cell fate commitmentGO:00451682100.021
homeostatic processGO:00425921990.021
nuclear divisionGO:00002803320.021
positive regulation of multi organism processGO:0043902400.021
compound eye developmentGO:00487493070.021
regulation of cellular amine metabolic processGO:003323830.021
cellular ketone metabolic processGO:0042180240.021
xenobiotic catabolic processGO:004217810.021
connective tissue developmentGO:006144830.020
cellular amino acid metabolic processGO:0006520610.020
phenol containing compound metabolic processGO:0018958570.020
chemotaxisGO:00069352490.020
developmental growthGO:00485892800.020
response to organonitrogen compoundGO:0010243750.020
response to organophosphorusGO:004668320.020
organophosphate metabolic processGO:00196371950.020
eye developmentGO:00016543230.019
cell proliferationGO:00082832990.019
amine metabolic processGO:0009308120.019
cellular amine metabolic processGO:0044106120.019
establishment of localization in cellGO:00516494020.019
negative regulation of rna metabolic processGO:00512532510.019
kidney morphogenesisGO:006099330.019
regulation of growthGO:00400082330.019
cellular response to organic substanceGO:00713101320.019
wound healingGO:0042060750.019
medium chain fatty acid metabolic processGO:005179110.019
negative regulation of biosynthetic processGO:00098902770.019
regulation of i kappab kinase nf kappab signalingGO:004312220.019
organic substance transportGO:00717022570.019
regulation of cellular component biogenesisGO:00440872010.019
protein localizationGO:00081042840.018
regulation of stress activated mapk cascadeGO:0032872410.018
negative regulation of rna biosynthetic processGO:19026792400.018
morphogenesis of an epitheliumGO:00020092760.018
neurological system processGO:00508773580.018
negative regulation of nucleic acid templated transcriptionGO:19035072400.018
regulation of cell differentiationGO:00455953020.018
regulation of cellular protein metabolic processGO:00322682430.018
neutral lipid biosynthetic processGO:004646020.018
positive regulation of rna biosynthetic processGO:19026802660.018
multicellular organismal agingGO:00102591400.018
macromolecular complex assemblyGO:00650032560.018
positive regulation of intracellular signal transductionGO:19025331160.018
regulation of molecular functionGO:00650092170.018
regulation of localizationGO:00328792750.017
regulation of phosphorylationGO:00423251470.017
compound eye morphogenesisGO:00017452490.017
single organism intracellular transportGO:19025822070.017
mitotic spindle organizationGO:00070522200.017
gene silencingGO:00164581380.017
steroid catabolic processGO:000670610.017
positive regulation of transcription dna templatedGO:00458932660.017
ras protein signal transductionGO:0007265880.017
sensory organ morphogenesisGO:00905962600.017
regulation of transcription from rna polymerase ii promoterGO:00063573780.017
protein transportGO:00150311550.017
negative regulation of immune responseGO:0050777390.017
columnar cuboidal epithelial cell differentiationGO:00020652560.017
telencephalon developmentGO:002153720.017
epithelial cell developmentGO:00020642740.017
negative regulation of developmental processGO:00510932010.017
negative regulation of innate immune responseGO:0045824300.017
tissue morphogenesisGO:00487292970.016
response to organic cyclic compoundGO:0014070890.016
regulation of protein metabolic processGO:00512462560.016
columnar cuboidal epithelial cell developmentGO:00020662490.016
organonitrogen compound catabolic processGO:19015651280.016
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.016
melanotic encapsulation of foreign targetGO:0035011300.016
vitamin biosynthetic processGO:000911010.016
benzene containing compound metabolic processGO:004253730.016
anion homeostasisGO:005508130.016
ovarian follicle cell developmentGO:00307072480.016
epithelial cell differentiationGO:00308553220.016
wnt signaling pathwayGO:0016055980.016
retina development in camera type eyeGO:006004140.016
actin filament organizationGO:00070151260.016
transcription from rna polymerase ii promoterGO:00063663680.016
cellular response to biotic stimulusGO:007121640.016
biological adhesionGO:00226101380.016
intracellular transportGO:00469072280.016
agingGO:00075681430.016
negative regulation of intracellular signal transductionGO:1902532570.016
jnk cascadeGO:0007254500.016
regulation of cellular ketone metabolic processGO:001056530.016
regulation of jnk cascadeGO:0046328400.016
actin cytoskeleton organizationGO:00300362060.016
heterocycle catabolic processGO:00467001660.016
negative regulation of defense responseGO:0031348350.015
cellular macromolecule localizationGO:00707272200.015
gland morphogenesisGO:00226121450.015
fat soluble vitamin biosynthetic processGO:004236210.015
cell divisionGO:00513012480.015
protein phosphorylationGO:00064681690.015
positive regulation of immune effector processGO:0002699280.015
organic cyclic compound catabolic processGO:19013611680.015
single organism cellular localizationGO:19025801800.015
localization of cellGO:00516742570.015
establishment of protein localizationGO:00451841630.015
aromatic compound catabolic processGO:00194391660.015
cell motilityGO:00488702510.015
fat soluble vitamin metabolic processGO:000677510.015
positive regulation of cell motilityGO:200014730.015
regulation of toll signaling pathwayGO:0008592170.015
single organism catabolic processGO:00447122280.015
spindle organizationGO:00070512530.015
regulation of cell cycle processGO:00105641810.015
synaptic transmissionGO:00072682880.015
mapk cascadeGO:00001651070.015
organelle assemblyGO:00709251980.015
kidney developmentGO:000182230.015
negative regulation of transcription dna templatedGO:00458922370.015
respiratory system developmentGO:00605412130.015
nucleobase containing small molecule metabolic processGO:00550861740.015
endomembrane system organizationGO:00102561190.015
small gtpase mediated signal transductionGO:0007264880.015
negative regulation of nucleobase containing compound metabolic processGO:00459342610.015
posttranscriptional regulation of gene expressionGO:00106081450.015
regulation of programmed cell deathGO:00430671520.015
extrinsic apoptotic signaling pathwayGO:009719110.014
deathGO:00162652840.014
negative regulation of macromolecule biosynthetic processGO:00105582700.014
nephron developmentGO:007200630.014
synapse assemblyGO:00074161430.014
cellular protein localizationGO:00346131600.014
cellular response to oxygen containing compoundGO:1901701790.014
hemolymph coagulationGO:0042381100.014
sensory perception of smellGO:0007608800.014
single organism cell adhesionGO:0098602470.014
vitamin metabolic processGO:000676620.014
developmental maturationGO:00217001720.014
regulation of cellular amino acid metabolic processGO:000652100.014
hormone catabolic processGO:004244730.014
ethanolamine containing compound metabolic processGO:004243940.014
rna processingGO:00063961470.014
cellular response to dna damage stimulusGO:00069742230.014
regulation of catalytic activityGO:00507901850.014
camera type eye morphogenesisGO:004859320.014
cellular nitrogen compound catabolic processGO:00442701650.014
taxisGO:00423303040.014
response to nutrient levelsGO:00316671140.014
chromosome segregationGO:00070591570.014
salivary gland developmentGO:00074311620.014
amine catabolic processGO:000931010.014
nephron epithelium developmentGO:007200930.014
detection of stimulusGO:00516061560.014
negative regulation of stress activated protein kinase signaling cascadeGO:0070303200.014
positive regulation of molecular functionGO:00440931360.014
lauric acid metabolic processGO:004825210.014
molting cycle chitin based cuticleGO:0007591560.014
regulation of organelle organizationGO:00330431960.014
response to radiationGO:00093141550.014
programmed cell deathGO:00125012570.014
stress activated protein kinase signaling cascadeGO:0031098550.014
regulation of catabolic processGO:00098941700.014
mitotic nuclear divisionGO:00070672130.014
protein complex biogenesisGO:00702712010.014
regulation of anatomical structure sizeGO:00900661630.014
eye morphogenesisGO:00485922600.014
response to monosaccharideGO:003428440.014
axon developmentGO:00615642970.014
intracellular protein transportGO:00068861040.013
embryonic development via the syncytial blastodermGO:00017001480.013
regulation of epithelial cell differentiationGO:003085640.013
single organismal cell cell adhesionGO:0016337450.013
positive regulation of phosphorus metabolic processGO:00105621390.013
nucleoside phosphate metabolic processGO:00067531620.013
sensory perception of chemical stimulusGO:00076061160.013
response to hexoseGO:000974630.013
estrogen metabolic processGO:000821010.013
epithelium migrationGO:00901321480.013
limb morphogenesisGO:003510810.013
regulation of cell deathGO:00109411730.013
nucleotide metabolic processGO:00091171610.013
cellular homeostasisGO:0019725800.013
regulation of gene expression epigeneticGO:00400291280.013
nephron tubule developmentGO:007208030.013
cell migrationGO:00164772380.013
g protein coupled receptor signaling pathwayGO:00071861360.013
regulation of mitotic cell cycleGO:00073461900.013
cell deathGO:00082192790.013
response to glucoseGO:000974920.013
cytolysisGO:001983510.013
mitotic cell cycle phase transitionGO:00447721380.013
positive regulation of apoptotic signaling pathwayGO:200123540.013
anatomical structure homeostasisGO:0060249970.013
rna localizationGO:00064031150.013
chromatin remodelingGO:0006338720.013
nephron morphogenesisGO:007202830.013
mesenchymal cell differentiationGO:004876210.013
cell adhesionGO:00071551360.013
single organism behaviorGO:00447083910.013
cellular response to chemical stimulusGO:00708871990.013
positive regulation of protein metabolic processGO:00512471280.013
regulation of gene silencingGO:0060968630.013
negative regulation of growthGO:0045926840.013
positive regulation of cellular component organizationGO:00511301560.013
insecticide catabolic processGO:004670110.013
cholesterol homeostasisGO:004263230.013
developmental programmed cell deathGO:00106231380.012
negative regulation of response to external stimulusGO:0032102220.012
chromosome organizationGO:00512763600.012
regulation of stress activated protein kinase signaling cascadeGO:0070302420.012
kidney epithelium developmentGO:007207330.012
multi organism behaviorGO:00517051750.012
mitotic dna integrity checkpointGO:0044774750.012
regulation of epithelial cell proliferationGO:005067840.012
positive regulation of phosphate metabolic processGO:00459371390.012
open tracheal system developmentGO:00074242040.012
neural retina developmentGO:000340740.012
positive regulation of catabolic processGO:00098961050.012
gland developmentGO:00487321910.012
positive regulation of multicellular organismal processGO:00512401430.012
protein complex assemblyGO:00064612000.012
regulation of developmental growthGO:00486381740.012
response to mercury ionGO:004668930.012
regulation of cell cycle phase transitionGO:19019871300.012
neuron projection guidanceGO:00974852410.012
negative regulation of cell cycle processGO:00109481090.012
spermatogenesisGO:00072832000.012
regulation of transportGO:00510491810.012
heterochromatin organizationGO:0070828250.012
regulation of cellular catabolic processGO:00313291570.012
regulation of synapse organizationGO:00508071100.012
regulation of lipid transportGO:003236830.012
positive regulation of innate immune responseGO:0045089380.012
dna methylation or demethylationGO:004472840.012
positive regulation of catalytic activityGO:00430851180.012
response to temperature stimulusGO:00092661060.012
toxin catabolic processGO:000940710.012
purine containing compound metabolic processGO:00725211550.012
exocrine system developmentGO:00352721620.012
negative regulation of cellular protein metabolic processGO:0032269850.012
oxidoreduction coenzyme metabolic processGO:000673320.012
regulation of mitotic cell cycle phase transitionGO:19019901300.012
response to copper ionGO:004668840.012
regulation of cell proliferationGO:00421271630.012
neuromuscular junction developmentGO:00075281490.012
regulation of anatomical structure morphogenesisGO:00226032420.012
nucleoside metabolic processGO:00091161270.012
anterior posterior axis specification embryoGO:00085951030.012
negative regulation of cell differentiationGO:00455961430.012
cell cycle checkpointGO:0000075950.012
dna metabolic processGO:00062592270.012
negative regulation of phosphate metabolic processGO:0045936450.012
negative regulation of multicellular organismal processGO:00512411420.012
protein maturationGO:0051604710.012
Fly
glycosyl compound metabolic processGO:19016571270.012
determination of adult lifespanGO:00083401370.012
meiotic cell cycleGO:00513211710.011
positive regulation of cellular amino acid metabolic processGO:004576400.011
regulation of ras protein signal transductionGO:0046578930.011
chaeta developmentGO:0022416970.011
cell cycle phase transitionGO:00447701400.011
positive regulation of nucleic acid templated transcriptionGO:19035082660.011
androgen metabolic processGO:000820910.011
pigmentationGO:0043473750.011
ameboidal type cell migrationGO:00016671510.011
ribonucleoside triphosphate metabolic processGO:00091991190.011
establishment of tissue polarityGO:0007164870.011
mrna metabolic processGO:00160711240.011
mesenchymal cell developmentGO:001403110.011
sterol homeostasisGO:005509240.011
male gamete generationGO:00482322010.011
regulation of hydrolase activityGO:0051336970.011
dna damage checkpointGO:0000077780.011
positive regulation of i kappab kinase nf kappab signalingGO:004312310.011
nephron epithelium morphogenesisGO:007208830.011
meiotic cell cycle processGO:19030461320.011
stem cell proliferationGO:0072089880.011
stem cell differentiationGO:00488631170.011
establishment of organelle localizationGO:00516561220.011
compound eye retinal cell programmed cell deathGO:0046667230.011
asymmetric stem cell divisionGO:0098722490.011
axonogenesisGO:00074092900.011
positive regulation of rna metabolic processGO:00512542710.011
negative regulation of phosphorylationGO:0042326350.011
outflow tract morphogenesisGO:000315140.011
regulation of cell substrate adhesionGO:001081020.011
nicotinamide nucleotide metabolic processGO:004649620.011
adult behaviorGO:00305341370.011
carbohydrate derivative catabolic processGO:19011361180.011
response to extracellular stimulusGO:00099911160.011
positive regulation of cellular component biogenesisGO:0044089800.011
molting cycle processGO:0022404290.011
imaginal disc derived wing vein specificationGO:0007474480.011
choline metabolic processGO:001969510.011
synapse organizationGO:00508081960.011
cellularizationGO:0007349900.011
regulation of protein localizationGO:0032880760.011
negative regulation of cell cycle phase transitionGO:19019881030.011
protein heterooligomerizationGO:005129140.011
hindbrain developmentGO:003090220.011
eye pigmentationGO:0048069430.011
regulation of apoptotic processGO:00429811300.011
regulation of proteolysisGO:0030162870.011
response to alcoholGO:0097305950.011
response to protozoanGO:000156230.011
ribonucleoside metabolic processGO:00091191270.011
organophosphate catabolic processGO:00464341120.011
digestive tract morphogenesisGO:00485461270.011
nucleobase containing compound catabolic processGO:00346551650.011
developmental pigmentationGO:0048066680.011
purine nucleoside triphosphate metabolic processGO:00091441190.011
epithelial cell migrationGO:00106311480.011
lipid metabolic processGO:00066291210.011
regulation of melanization defense responseGO:003500760.011
protein modification by small protein conjugation or removalGO:00706471060.011
purine ribonucleoside metabolic processGO:00461281270.011
regulation of nervous system developmentGO:00519602480.011

spirit disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.044
inherited metabolic disorderDOID:65500.016
disease of metabolismDOID:001466700.016
nervous system diseaseDOID:86300.015
disease of cellular proliferationDOID:1456600.014
essential hypertensionDOID:1082500.013
vascular diseaseDOID:17800.013
hypertensionDOID:1076300.013
cardiovascular system diseaseDOID:128700.013
artery diseaseDOID:005082800.013
cancerDOID:16200.013
organ system cancerDOID:005068600.012