IMP: Integrative Multi-species Prediction

Drosophila melanogaster

23 known processes

CG6776 (Dmel_CG6776)

CG6776 gene product from transcript CG6776-RA

(Aliases: T14,Dmel\CG6776)

Entrez: 38972
FLYBASE: FBgn0035904
UniProtKB: Q9VSL2

Process Predictions
Disease Predictions

CG6776 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
glutathione metabolic process	GO:0006749	37	0.941
cellular modified amino acid metabolic process	GO:0006575	45	0.910
peptide metabolic process	GO:0006518	80	0.649
response to abiotic stimulus	GO:0009628	341	0.427
cellular amide metabolic process	GO:0043603	80	0.334
sulfur compound metabolic process	GO:0006790	59	0.232
organic acid metabolic process	GO:0006082	103	0.219
carboxylic acid metabolic process	GO:0019752	92	0.180
small molecule metabolic process	GO:0044281	305	0.173
metal ion homeostasis	GO:0055065	44	0.151	Human
cation homeostasis	GO:0055080	51	0.129	Human
cellular amino acid metabolic process	GO:0006520	61	0.128
ion homeostasis	GO:0050801	55	0.125	Human
oxoacid metabolic process	GO:0043436	103	0.117
cellular cation homeostasis	GO:0030003	38	0.115	Human
intracellular transport	GO:0046907	228	0.112	Human
cell proliferation	GO:0008283	299	0.109
response to alcohol	GO:0097305	95	0.107
developmental pigmentation	GO:0048066	68	0.107	Fly
response to oxidative stress	GO:0006979	86	0.097
cellular response to chemical stimulus	GO:0070887	199	0.096	Human
cellular homeostasis	GO:0019725	80	0.094	Human
programmed cell death	GO:0012501	257	0.091
regulation of cell death	GO:0010941	173	0.090
response to organic substance	GO:0010033	284	0.085
cell death	GO:0008219	279	0.083
organonitrogen compound metabolic process	GO:1901564	318	0.082
catabolic process	GO:0009056	409	0.082	Human
dorsal ventral pattern formation	GO:0009953	133	0.078
single organism intracellular transport	GO:1902582	207	0.077	Human
regulation of localization	GO:0032879	275	0.074	Human
establishment of localization in cell	GO:0051649	402	0.072	Human
nucleotide metabolic process	GO:0009117	161	0.071
oxidation reduction process	GO:0055114	123	0.068
response to heat	GO:0009408	63	0.066
anatomical structure homeostasis	GO:0060249	97	0.065
regionalization	GO:0003002	416	0.064
response to temperature stimulus	GO:0009266	106	0.063
negative regulation of cell communication	GO:0010648	223	0.062
response to osmotic stress	GO:0006970	14	0.061
pyridine containing compound metabolic process	GO:0072524	3	0.060
negative regulation of signal transduction	GO:0009968	206	0.059
negative regulation of cellular metabolic process	GO:0031324	382	0.058
regulation of anatomical structure size	GO:0090066	163	0.058
wing disc morphogenesis	GO:0007472	344	0.057
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.057
regulation of immune response	GO:0050776	118	0.057
cellular chemical homeostasis	GO:0055082	40	0.056	Human
nicotinamide nucleotide metabolic process	GO:0046496	2	0.055
homeostatic process	GO:0042592	199	0.054	Human
regulation of cell proliferation	GO:0042127	163	0.054
regulation of cellular localization	GO:0060341	136	0.052	Human
cellular catabolic process	GO:0044248	372	0.052	Human
wing disc pattern formation	GO:0035222	66	0.051
membrane organization	GO:0061024	112	0.051
regulation of apoptotic process	GO:0042981	130	0.051
organic substance catabolic process	GO:1901575	308	0.050
epithelial cell differentiation	GO:0030855	322	0.046
chemical homeostasis	GO:0048878	92	0.045	Human
organic cyclic compound catabolic process	GO:1901361	168	0.045
cellular ion homeostasis	GO:0006873	39	0.044	Human
macromolecular complex assembly	GO:0065003	256	0.043
eye pigment biosynthetic process	GO:0006726	32	0.043	Fly
nucleoside phosphate metabolic process	GO:0006753	162	0.043
organic substance transport	GO:0071702	257	0.043
monocarboxylic acid metabolic process	GO:0032787	29	0.043
positive regulation of response to stimulus	GO:0048584	323	0.042
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.042
cellular aldehyde metabolic process	GO:0006081	10	0.042
immune system process	GO:0002376	347	0.041
death	GO:0016265	284	0.040
protein complex biogenesis	GO:0070271	201	0.039
apoptotic process	GO:0006915	159	0.038
cellular ketone metabolic process	GO:0042180	24	0.038
single organism biosynthetic process	GO:0044711	206	0.038	Rat Fly
post embryonic appendage morphogenesis	GO:0035120	385	0.037
positive regulation of cell communication	GO:0010647	250	0.037
regulation of transport	GO:0051049	181	0.037	Human
positive regulation of signal transduction	GO:0009967	223	0.036
glycosyl compound metabolic process	GO:1901657	127	0.036
divalent metal ion transport	GO:0070838	26	0.036	Human
regulation of programmed cell death	GO:0043067	152	0.036
appendage morphogenesis	GO:0035107	397	0.035
response to salt stress	GO:0009651	11	0.034
organonitrogen compound biosynthetic process	GO:1901566	117	0.034	Fly
pyridine nucleotide metabolic process	GO:0019362	2	0.034
imaginal disc derived appendage development	GO:0048737	399	0.033
response to ethanol	GO:0045471	59	0.033
oxidoreduction coenzyme metabolic process	GO:0006733	2	0.033
intracellular signal transduction	GO:0035556	300	0.033
nucleobase containing small molecule metabolic process	GO:0055086	174	0.032
regulation of multi organism process	GO:0043900	131	0.032
divalent inorganic cation homeostasis	GO:0072507	29	0.031	Human
single organism behavior	GO:0044708	391	0.031
salivary gland morphogenesis	GO:0007435	145	0.030
regulation of response to stress	GO:0080134	200	0.030
regulation of molecular function	GO:0065009	217	0.030	Human
forebrain development	GO:0030900	2	0.030
regulation of intracellular transport	GO:0032386	64	0.030	Human
positive regulation of signaling	GO:0023056	243	0.030
calcium ion transport	GO:0006816	24	0.029	Human
regulation of multicellular organismal development	GO:2000026	414	0.029
single organism membrane organization	GO:0044802	93	0.029
regulation of cellular component size	GO:0032535	98	0.029
regulation of response to external stimulus	GO:0032101	115	0.029
brain development	GO:0007420	120	0.029
immune effector process	GO:0002252	98	0.028
response to inorganic substance	GO:0010035	44	0.028
protein complex assembly	GO:0006461	200	0.028
cellular amine metabolic process	GO:0044106	12	0.028
negative regulation of rna metabolic process	GO:0051253	251	0.028
pigmentation	GO:0043473	75	0.028	Fly
response to bacterium	GO:0009617	198	0.027
vesicle mediated transport	GO:0016192	381	0.027
protein localization	GO:0008104	284	0.027
proteolysis	GO:0006508	192	0.027
male sex differentiation	GO:0046661	25	0.026
carbohydrate biosynthetic process	GO:0016051	17	0.026	Rat
response to hypoxia	GO:0001666	53	0.026
regulation of immune system process	GO:0002682	176	0.025
regulation of anatomical structure morphogenesis	GO:0022603	242	0.025
lipid catabolic process	GO:0016042	21	0.025
kidney development	GO:0001822	3	0.025
cellular metal ion homeostasis	GO:0006875	31	0.024	Human
cell aging	GO:0007569	2	0.024
appendage development	GO:0048736	401	0.023
eye pigment metabolic process	GO:0042441	33	0.023	Fly
imaginal disc derived wing morphogenesis	GO:0007476	337	0.023
divalent inorganic cation transport	GO:0072511	30	0.023	Human
carbohydrate derivative metabolic process	GO:1901135	217	0.023
regulation of cellular ketone metabolic process	GO:0010565	3	0.022
endosomal transport	GO:0016197	44	0.022
response to radiation	GO:0009314	155	0.022
negative regulation of gene expression	GO:0010629	387	0.022
negative regulation of cellular biosynthetic process	GO:0031327	277	0.022
regulation of catabolic process	GO:0009894	170	0.022
response to organic cyclic compound	GO:0014070	89	0.022
organophosphate metabolic process	GO:0019637	195	0.022
posttranscriptional regulation of gene expression	GO:0010608	145	0.020
androgen metabolic process	GO:0008209	1	0.020
regulation of intracellular signal transduction	GO:1902531	236	0.020
imaginal disc derived wing margin morphogenesis	GO:0008587	41	0.019
transcription from rna polymerase ii promoter	GO:0006366	368	0.019
mushroom body development	GO:0016319	70	0.019
positive regulation of intracellular signal transduction	GO:1902533	116	0.019
body morphogenesis	GO:0010171	2	0.019
chaeta development	GO:0022416	97	0.019
cation transport	GO:0006812	110	0.019	Human
regulation of cell shape	GO:0008360	113	0.019
regulation of notch signaling pathway	GO:0008593	100	0.019
regulation of cell morphogenesis	GO:0022604	163	0.019
eye pigmentation	GO:0048069	43	0.018	Fly
regulation of organelle organization	GO:0033043	196	0.018
notch signaling pathway	GO:0007219	120	0.018
imaginal disc pattern formation	GO:0007447	91	0.018
negative regulation of rna biosynthetic process	GO:1902679	240	0.018
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.018
regulation of protein metabolic process	GO:0051246	256	0.018
exocrine system development	GO:0035272	162	0.018
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.018
salivary gland development	GO:0007431	162	0.018
cytoplasmic transport	GO:0016482	130	0.018	Human
response to biotic stimulus	GO:0009607	294	0.017
response to oxygen levels	GO:0070482	59	0.017
basolateral protein localization	GO:0061467	1	0.017
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.017
epithelial cell development	GO:0002064	274	0.017
estrogen metabolic process	GO:0008210	1	0.017
cellular response to nutrient levels	GO:0031669	62	0.017
lipid metabolic process	GO:0006629	121	0.017
response to oxygen containing compound	GO:1901700	200	0.017
amine metabolic process	GO:0009308	12	0.017
cellular protein modification process	GO:0006464	438	0.017
tissue death	GO:0016271	102	0.017
gland development	GO:0048732	191	0.016
developmental growth	GO:0048589	280	0.016
organic hydroxy compound metabolic process	GO:1901615	83	0.016
developmental programmed cell death	GO:0010623	138	0.016
response to other organism	GO:0051707	293	0.016
regulation of response to wounding	GO:1903034	19	0.016
ion transmembrane transport	GO:0034220	122	0.016	Human
cellular response to extracellular stimulus	GO:0031668	64	0.016
positive regulation of cell migration	GO:0030335	2	0.016
cellular response to external stimulus	GO:0071496	66	0.016
dna metabolic process	GO:0006259	227	0.016
gland morphogenesis	GO:0022612	145	0.016
negative regulation of programmed cell death	GO:0043069	72	0.016
jak stat cascade	GO:0007259	49	0.016
wing disc dorsal ventral pattern formation	GO:0048190	47	0.016
dorsal ventral pattern formation imaginal disc	GO:0007450	51	0.016
establishment or maintenance of cell polarity	GO:0007163	167	0.015
cellular response to organic substance	GO:0071310	132	0.015
response to decreased oxygen levels	GO:0036293	58	0.015
protein transport	GO:0015031	155	0.015
single organism carbohydrate metabolic process	GO:0044723	72	0.015	Human Rat
aggressive behavior	GO:0002118	63	0.015
regulation of cell differentiation	GO:0045595	302	0.015
lateral inhibition	GO:0046331	206	0.015
regulation of catalytic activity	GO:0050790	185	0.015
negative regulation of biosynthetic process	GO:0009890	277	0.015
negative regulation of response to stimulus	GO:0048585	258	0.015
protein modification process	GO:0036211	438	0.015
response to light stimulus	GO:0009416	124	0.015
intracellular protein transport	GO:0006886	104	0.014
negative regulation of signaling	GO:0023057	219	0.014
endocytosis	GO:0006897	310	0.014
multi organism behavior	GO:0051705	175	0.014
regulation of cell cycle	GO:0051726	291	0.014
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.014
cation transmembrane transport	GO:0098655	88	0.014	Human
nucleoside metabolic process	GO:0009116	127	0.014
telencephalon development	GO:0021537	2	0.014
positive regulation of cell death	GO:0010942	69	0.013
negative regulation of cell death	GO:0060548	81	0.013
regulation of cellular protein metabolic process	GO:0032268	243	0.013
negative regulation of sequestering of calcium ion	GO:0051283	2	0.013	Human
mrna processing	GO:0006397	104	0.013
cell adhesion	GO:0007155	136	0.013
regulation of imaginal disc derived wing size	GO:0044719	20	0.013
head development	GO:0060322	135	0.013
alcohol metabolic process	GO:0006066	25	0.013
cellular nitrogen compound catabolic process	GO:0044270	165	0.013
regulation of nervous system development	GO:0051960	248	0.013
organonitrogen compound catabolic process	GO:1901565	128	0.013
small gtpase mediated signal transduction	GO:0007264	88	0.013
localization of cell	GO:0051674	257	0.013
carbohydrate derivative catabolic process	GO:1901136	118	0.013
response to copper ion	GO:0046688	4	0.013
mitochondrion organization	GO:0007005	65	0.012
response to monosaccharide	GO:0034284	4	0.012
negative regulation of molecular function	GO:0044092	51	0.012	Human
acyl coa metabolic process	GO:0006637	3	0.012
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.012
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.012
growth	GO:0040007	359	0.012
maintenance of cell polarity	GO:0030011	18	0.012
regulation of neuron differentiation	GO:0045664	103	0.012
positive regulation of calcium ion transport	GO:0051928	4	0.012	Human
actin filament organization	GO:0007015	126	0.012
metal ion transport	GO:0030001	74	0.012	Human
biological adhesion	GO:0022610	138	0.012
ras protein signal transduction	GO:0007265	88	0.012
protein import into nucleus	GO:0006606	51	0.012
development of primary male sexual characteristics	GO:0046546	9	0.012
water soluble vitamin metabolic process	GO:0006767	1	0.012	Human Rat
response to hexose	GO:0009746	3	0.012
centrosome duplication	GO:0051298	121	0.012
regulation of multivesicular body size involved in endosome transport	GO:0010797	2	0.012
cellular protein localization	GO:0034613	160	0.012
response to glucose	GO:0009749	2	0.012
cellular macromolecular complex assembly	GO:0034622	153	0.012
response to nutrient levels	GO:0031667	114	0.012
positive regulation of molecular function	GO:0044093	136	0.012	Human
heterocycle catabolic process	GO:0046700	166	0.012
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.012
cellular lipid metabolic process	GO:0044255	83	0.011
small molecule biosynthetic process	GO:0044283	37	0.011	Rat
positive regulation of cellular component organization	GO:0051130	156	0.011
central nervous system development	GO:0007417	201	0.011
aging	GO:0007568	143	0.011
regulation of phosphate metabolic process	GO:0019220	210	0.011
positive regulation of cell motility	GO:2000147	3	0.011
cellular response to endogenous stimulus	GO:0071495	80	0.011
pigment metabolic process	GO:0042440	84	0.011	Fly
negative regulation of cell differentiation	GO:0045596	143	0.011
response to wounding	GO:0009611	94	0.011
carboxylic acid biosynthetic process	GO:0046394	15	0.011	Rat
salivary gland histolysis	GO:0035070	88	0.011
response to water deprivation	GO:0009414	4	0.011
positive regulation of cell proliferation	GO:0008284	47	0.011
organic acid biosynthetic process	GO:0016053	15	0.011	Rat
positive regulation of cellular biosynthetic process	GO:0031328	316	0.011
release of sequestered calcium ion into cytosol	GO:0051209	1	0.011	Human
camera type eye development	GO:0043010	4	0.010
negative regulation of multicellular organismal process	GO:0051241	142	0.010
signal transduction by phosphorylation	GO:0023014	107	0.010
salivary gland cell autophagic cell death	GO:0035071	83	0.010
single organism catabolic process	GO:0044712	228	0.010
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.010
regulation of organ morphogenesis	GO:2000027	78	0.010
sensory organ morphogenesis	GO:0090596	260	0.010
age dependent response to oxidative stress	GO:0001306	3	0.010
response to calcium ion	GO:0051592	1	0.010
nucleotide catabolic process	GO:0009166	109	0.010
organophosphate catabolic process	GO:0046434	112	0.010
regulation of cellular catabolic process	GO:0031329	157	0.010

CG6776 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.035
musculoskeletal system disease	DOID:17	0.026
inherited metabolic disorder	DOID:655	0.020
disease of metabolism	DOID:0014667	0.020
bone disease	DOID:0080001	0.019
connective tissue disease	DOID:65	0.019
disease of cellular proliferation	DOID:14566	0.018
cancer	DOID:162	0.015
bone development disease	DOID:0080006	0.013
organ system cancer	DOID:0050686	0.011
nervous system disease	DOID:863	0.011

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