Drosophila melanogaster

15 known processes

Twdlalpha (Dmel_CG32574)

Tweedlealpha

(Aliases: CG32574,CG4724,Dmel\CG32574)

Twdlalpha biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
lateral inhibitionGO:00463312060.072
response to abiotic stimulusGO:00096283410.049
catabolic processGO:00090564090.048
positive regulation of macromolecule metabolic processGO:00106044050.047
organonitrogen compound metabolic processGO:19015643180.046
protein modification processGO:00362114380.046
defense responseGO:00069523000.044
response to biotic stimulusGO:00096072940.043
defense response to bacteriumGO:00427421780.038
positive regulation of response to stimulusGO:00485843230.038
vesicle mediated transportGO:00161923810.038
negative regulation of cellular metabolic processGO:00313243820.038
cellular catabolic processGO:00442483720.038
negative regulation of gene expressionGO:00106293870.036
spermatogenesisGO:00072832000.036
wing disc morphogenesisGO:00074723440.035
small molecule metabolic processGO:00442813050.035
body morphogenesisGO:001017120.035
Fly
neurological system processGO:00508773580.035
endocytosisGO:00068973100.034
protein localizationGO:00081042840.033
proteolysisGO:00065081920.032
cell cell signaling involved in cell fate commitmentGO:00451682100.031
response to bacteriumGO:00096171980.031
appendage developmentGO:00487364010.031
cellular response to dna damage stimulusGO:00069742230.031
establishment of localization in cellGO:00516494020.030
imaginal disc derived wing morphogenesisGO:00074763370.030
intracellular signal transductionGO:00355563000.030
regulation of intracellular signal transductionGO:19025312360.030
cellular protein modification processGO:00064644380.030
mitotic spindle organizationGO:00070522200.030
organic substance transportGO:00717022570.029
positive regulation of signalingGO:00230562430.029
male gamete generationGO:00482322010.029
organic substance catabolic processGO:19015753080.029
organelle fissionGO:00482853400.029
oxoacid metabolic processGO:00434361030.028
single organism catabolic processGO:00447122280.028
positive regulation of nucleic acid templated transcriptionGO:19035082660.028
carboxylic acid metabolic processGO:0019752920.028
positive regulation of cellular biosynthetic processGO:00313283160.027
positive regulation of signal transductionGO:00099672230.027
single organism cellular localizationGO:19025801800.027
cell deathGO:00082192790.027
post embryonic appendage morphogenesisGO:00351203850.027
response to external biotic stimulusGO:00432072930.027
regionalizationGO:00030024160.027
appendage morphogenesisGO:00351073970.026
defense response to other organismGO:00985422250.026
cellular macromolecule localizationGO:00707272200.026
transcription from rna polymerase ii promoterGO:00063663680.026
negative regulation of nucleobase containing compound metabolic processGO:00459342610.026
positive regulation of nucleobase containing compound metabolic processGO:00459353320.026
regulation of cellular protein metabolic processGO:00322682430.026
protein transportGO:00150311550.025
taxisGO:00423303040.025
response to organic substanceGO:00100332840.025
organic acid metabolic processGO:00060821030.025
positive regulation of transcription dna templatedGO:00458932660.024
response to other organismGO:00517072930.024
regulation of transcription from rna polymerase ii promoterGO:00063573780.024
multi multicellular organism processGO:00447061230.024
immune system processGO:00023763470.024
negative regulation of cellular biosynthetic processGO:00313272770.024
mitotic nuclear divisionGO:00070672130.024
spermatid developmentGO:0007286980.024
regulation of protein metabolic processGO:00512462560.024
chromosome organizationGO:00512763600.024
establishment of protein localizationGO:00451841630.024
organelle assemblyGO:00709251980.024
eye morphogenesisGO:00485922600.023
phosphorylationGO:00163102940.023
imaginal disc derived appendage morphogenesisGO:00351143950.023
protein targetingGO:0006605640.023
spermatid differentiationGO:00485151140.023
deathGO:00162652840.023
spindle organizationGO:00070512530.023
cellular response to chemical stimulusGO:00708871990.023
negative regulation of biosynthetic processGO:00098902770.022
regulation of multicellular organismal developmentGO:20000264140.022
cytoplasmic transportGO:00164821300.022
amine metabolic processGO:0009308120.022
immune responseGO:00069552460.022
regulation of catalytic activityGO:00507901850.022
positive regulation of macromolecule biosynthetic processGO:00105572830.022
response to oxygen containing compoundGO:19017002000.022
sterol homeostasisGO:005509240.022
developmental programmed cell deathGO:00106231380.022
positive regulation of nitrogen compound metabolic processGO:00511733540.021
positive regulation of rna metabolic processGO:00512542710.021
response to lipopolysaccharideGO:003249640.021
single organism behaviorGO:00447083910.021
forebrain developmentGO:003090020.021
imaginal disc derived appendage developmentGO:00487373990.021
positive regulation of biosynthetic processGO:00098913160.021
regulation of response to stressGO:00801342000.021
nuclear divisionGO:00002803320.021
regulation of cellular amine metabolic processGO:003323830.021
gene silencingGO:00164581380.020
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.020
phagocytosisGO:00069092150.020
axon developmentGO:00615642970.020
programmed cell deathGO:00125012570.020
positive regulation of cell communicationGO:00106472500.020
cellular amine metabolic processGO:0044106120.020
carbohydrate derivative metabolic processGO:19011352170.020
negative regulation of macromolecule biosynthetic processGO:00105582700.020
protein localization to organelleGO:0033365820.019
regulation of cell cycleGO:00517262910.019
cellularizationGO:0007349900.019
positive regulation of rna biosynthetic processGO:19026802660.019
eye developmentGO:00016543230.019
anion homeostasisGO:005508130.019
cellular protein localizationGO:00346131600.019
ethanolamine containing compound metabolic processGO:004243940.019
cell cycle phase transitionGO:00447701400.019
regulation of localizationGO:00328792750.019
negative regulation of nucleic acid templated transcriptionGO:19035072400.019
macromolecule catabolic processGO:00090571610.019
negative regulation of transcription dna templatedGO:00458922370.019
sensory organ morphogenesisGO:00905962600.019
single organism intracellular transportGO:19025822070.018
negative regulation of rna metabolic processGO:00512532510.018
cilium assemblyGO:0042384380.018
intracellular protein transportGO:00068861040.018
camera type eye developmentGO:004301040.018
regulation of mitotic cell cycleGO:00073461900.018
regulation of molecular functionGO:00650092170.018
compound eye developmentGO:00487493070.018
homeostatic processGO:00425921990.018
regulation of gene expression epigeneticGO:00400291280.018
single organism biosynthetic processGO:00447112060.018
sperm individualizationGO:0007291480.017
regulation of phosphorus metabolic processGO:00511742100.017
organophosphate metabolic processGO:00196371950.017
macromolecular complex assemblyGO:00650032560.017
compound eye morphogenesisGO:00017452490.017
positive regulation of intracellular signal transductionGO:19025331160.017
regulation of cellular ketone metabolic processGO:001056530.017
organelle localizationGO:00516401480.017
regulation of cell cycle phase transitionGO:19019871300.017
negative regulation of rna biosynthetic processGO:19026792400.017
cellular lipid metabolic processGO:0044255830.016
cell proliferationGO:00082832990.016
ubiquitin dependent protein catabolic processGO:0006511780.016
sensory perceptionGO:00076001960.016
positive regulation of gene expressionGO:00106282900.016
apoptotic processGO:00069151590.016
posttranscriptional regulation of gene expressionGO:00106081450.016
response to temperature stimulusGO:00092661060.016
organic hydroxy compound metabolic processGO:1901615830.016
response to nutrient levelsGO:00316671140.016
cellular macromolecule catabolic processGO:00442651360.016
cellular ketone metabolic processGO:0042180240.016
negative regulation of nitrogen compound metabolic processGO:00511722650.016
response to extracellular stimulusGO:00099911160.016
regulation of proteolysisGO:0030162870.016
cell divisionGO:00513012480.016
phosphatidylethanolamine metabolic processGO:004633710.016
regulation of cell cycle processGO:00105641810.015
protein phosphorylationGO:00064681690.015
regulation of catabolic processGO:00098941700.015
cell cycle checkpointGO:0000075950.015
glycerolipid catabolic processGO:004650330.015
photoreceptor cell differentiationGO:00465301700.015
chromosome segregationGO:00070591570.015
regulation of cellular catabolic processGO:00313291570.015
regulation of cell differentiationGO:00455953020.015
kidney developmentGO:000182230.015
adult behaviorGO:00305341370.015
cellular protein catabolic processGO:0044257830.015
mitotic cell cycle phase transitionGO:00447721380.015
developmental maturationGO:00217001720.015
negative regulation of protein metabolic processGO:0051248850.015
regulation of cellular amino acid metabolic processGO:000652100.015
protein catabolic processGO:00301631010.015
epithelial cell differentiationGO:00308553220.015
regulation of mitotic cell cycle phase transitionGO:19019901300.015
intracellular transportGO:00469072280.015
dna integrity checkpointGO:0031570810.015
chemotaxisGO:00069352490.015
cellular amide metabolic processGO:0043603800.014
axonogenesisGO:00074092900.014
regulation of transportGO:00510491810.014
mitotic sister chromatid segregationGO:0000070870.014
cellular component assembly involved in morphogenesisGO:00109271510.014
regulation of programmed cell deathGO:00430671520.014
protein complex biogenesisGO:00702712010.014
regulation of immune system processGO:00026821760.014
triglyceride catabolic processGO:001943330.014
response to woundingGO:0009611940.014
cell migrationGO:00164772380.014
locomotory behaviorGO:00076261760.014
segmentationGO:00352822070.014
regulation of cell deathGO:00109411730.014
negative regulation of cellular protein metabolic processGO:0032269850.014
neuron projection guidanceGO:00974852410.014
wound healingGO:0042060750.014
telencephalon developmentGO:002153720.014
positive regulation of cellular amine metabolic processGO:003324000.014
localization of cellGO:00516742570.014
positive regulation of cell motilityGO:200014730.014
rna localizationGO:00064031150.014
modification dependent macromolecule catabolic processGO:0043632790.014
dendrite developmentGO:00163582040.014
humoral immune responseGO:00069591170.014
regulation of apoptotic processGO:00429811300.014
negative regulation of cell deathGO:0060548810.014
ras protein signal transductionGO:0007265880.014
small gtpase mediated signal transductionGO:0007264880.013
response to alcoholGO:0097305950.013
ribonucleoside triphosphate metabolic processGO:00091991190.013
axon guidanceGO:00074112330.013
cellular homeostasisGO:0019725800.013
axis specificationGO:00097981670.013
protein complex assemblyGO:00064612000.013
positive regulation of cellular component biogenesisGO:0044089800.013
establishment of protein localization to organelleGO:0072594620.013
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.013
response to organophosphorusGO:004668320.013
dna damage checkpointGO:0000077780.013
proteolysis involved in cellular protein catabolic processGO:0051603830.013
protein modification by small protein conjugation or removalGO:00706471060.013
acetylcholine metabolic processGO:000829120.013
positive regulation of catabolic processGO:00098961050.013
developmental growthGO:00485892800.013
positive regulation of molecular functionGO:00440931360.013
cellular response to organic substanceGO:00713101320.013
positive regulation of apoptotic signaling pathwayGO:200123540.013
protein modification by small protein conjugationGO:0032446790.013
histolysisGO:00075591020.013
cellular nitrogen compound catabolic processGO:00442701650.013
dendrite morphogenesisGO:00488131990.013
regulation of nervous system developmentGO:00519602480.013
regulation of anatomical structure morphogenesisGO:00226032420.013
dna metabolic processGO:00062592270.013
organic cyclic compound catabolic processGO:19013611680.013
sister chromatid segregationGO:0000819920.013
regulation of cell developmentGO:00602842150.012
negative regulation of multicellular organismal processGO:00512411420.012
regulation of hydrolase activityGO:0051336970.012
gland developmentGO:00487321910.012
regulation of phosphate metabolic processGO:00192202100.012
positive regulation of phosphorus metabolic processGO:00105621390.012
spindle assemblyGO:0051225800.012
protein transmembrane transportGO:007180640.012
organonitrogen compound catabolic processGO:19015651280.012
innate immune responseGO:00450871440.012
purine ribonucleoside triphosphate metabolic processGO:00092051190.012
positive regulation of protein metabolic processGO:00512471280.012
nucleotide metabolic processGO:00091171610.012
modification dependent protein catabolic processGO:0019941780.012
cell agingGO:000756920.012
negative regulation of signal transductionGO:00099682060.012
peptide metabolic processGO:0006518800.012
nucleoside phosphate metabolic processGO:00067531620.012
embryonic pattern specificationGO:00098801740.012
regulation of organelle organizationGO:00330431960.012
aromatic compound catabolic processGO:00194391660.012
wnt signaling pathwayGO:0016055980.012
proteasomal protein catabolic processGO:0010498590.012
regulation of cell substrate adhesionGO:001081020.012
monocarboxylic acid transportGO:001571830.012
purine ribonucleoside triphosphate catabolic processGO:00092071080.012
regulation of synapse structure and activityGO:00508031280.012
biological adhesionGO:00226101380.012
retina development in camera type eyeGO:006004140.012
salt aversionGO:003519930.012
negative regulation of developmental processGO:00510932010.012
compound eye photoreceptor cell differentiationGO:00017511400.012
positive regulation of catalytic activityGO:00430851180.012
growthGO:00400073590.012
response to copper ionGO:004668840.012
nucleoside metabolic processGO:00091161270.012
chromatin silencingGO:0006342760.012
regulation of i kappab kinase nf kappab signalingGO:004312220.012
lipid metabolic processGO:00066291210.012
chaeta developmentGO:0022416970.012
nucleobase containing compound catabolic processGO:00346551650.012
protein processingGO:0016485680.012
response to radiationGO:00093141550.012
anatomical structure homeostasisGO:0060249970.012
carbohydrate derivative catabolic processGO:19011361180.012
cellular modified amino acid metabolic processGO:0006575450.012
fat soluble vitamin metabolic processGO:000677510.012
chemical homeostasisGO:0048878920.012
heterocycle catabolic processGO:00467001660.012
protein maturationGO:0051604710.012
positive regulation of cellular amino acid metabolic processGO:004576400.012
ribonucleotide catabolic processGO:00092611090.012
cilium morphogenesisGO:0060271390.012
negative regulation of response to stimulusGO:00485852580.011
regulation of defense responseGO:00313471020.011
negative regulation of gene expression epigeneticGO:0045814770.011
purine nucleotide metabolic processGO:00061631460.011
muscle structure developmentGO:00610612240.011
purine nucleoside triphosphate metabolic processGO:00091441190.011
synaptic transmissionGO:00072682880.011
positive regulation of cellular catabolic processGO:0031331950.011
positive regulation of phosphate metabolic processGO:00459371390.011
triglyceride biosynthetic processGO:001943220.011
cellular amino acid metabolic processGO:0006520610.011
signal transduction by phosphorylationGO:00230141070.011
establishment or maintenance of cell polarityGO:00071631670.011
cognitionGO:00508901410.011
regulation of lipid transportGO:003236830.011
embryo development ending in birth or egg hatchingGO:00097921520.011
gland morphogenesisGO:00226121450.011
purine ribonucleotide metabolic processGO:00091501450.011
negative regulation of cell differentiationGO:00455961430.011
mesenchymal cell developmentGO:001403110.011
mitotic sister chromatid separationGO:0051306300.011
response to hexoseGO:000974630.011
somatic muscle developmentGO:0007525660.011
cholesterol homeostasisGO:004263230.011
regulation of cellular component biogenesisGO:00440872010.011
negative regulation of apoptotic processGO:0043066630.011
cell projection assemblyGO:0030031940.011
posttranscriptional gene silencing by rnaGO:0035194450.011
salivary gland morphogenesisGO:00074351450.011
positive regulation of multicellular organismal processGO:00512401430.011
blastoderm segmentationGO:00073501590.011
morphogenesis of an epitheliumGO:00020092760.011
purine ribonucleoside metabolic processGO:00461281270.011
central nervous system developmentGO:00074172010.011
salivary gland developmentGO:00074311620.011
dorsal ventral pattern formationGO:00099531330.011
response to endogenous stimulusGO:00097191190.011
columnar cuboidal epithelial cell differentiationGO:00020652560.011
female meiotic divisionGO:0007143700.011
eye photoreceptor cell differentiationGO:00017541450.011
negative regulation of signalingGO:00230572190.011
mitochondrion organizationGO:0007005650.011
regulation of mapk cascadeGO:0043408920.011
organophosphate catabolic processGO:00464341120.011
anterior posterior axis specificationGO:00099481090.011
mapk cascadeGO:00001651070.011
synapse organizationGO:00508081960.011
nucleoside phosphate catabolic processGO:19012921100.011
carbohydrate metabolic processGO:0005975820.011
neutral lipid biosynthetic processGO:004646020.011
endomembrane system organizationGO:00102561190.011
mesenchymal cell differentiationGO:004876210.011
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.011
anterior posterior pattern specificationGO:00099521360.011
jak stat cascadeGO:0007259490.011
purine nucleoside metabolic processGO:00422781270.011
tripartite regional subdivisionGO:00073511030.011
ribonucleoside metabolic processGO:00091191270.011
regulation of anatomical structure sizeGO:00900661630.010
purine nucleoside triphosphate catabolic processGO:00091461080.010
purine nucleotide catabolic processGO:00061951090.010
pyridine containing compound metabolic processGO:007252430.010
positive regulation of hydrolase activityGO:0051345780.010
acylglycerol biosynthetic processGO:004646320.010
tissue morphogenesisGO:00487292970.010
response to nitrogen compoundGO:1901698900.010
reproductive behaviorGO:00190981220.010
purine ribonucleotide catabolic processGO:00091541090.010
matingGO:00076181200.010
regulation of phosphorylationGO:00423251470.010
organonitrogen compound biosynthetic processGO:19015661170.010
detection of abiotic stimulusGO:0009582660.010
cholesterol transportGO:003030120.010
purine nucleoside catabolic processGO:00061521120.010
sulfur compound metabolic processGO:0006790590.010
purine containing compound metabolic processGO:00725211550.010
nucleoside triphosphate catabolic processGO:00091431080.010
salivary gland histolysisGO:0035070880.010
ion transmembrane transportGO:00342201220.010
cell adhesionGO:00071551360.010
regulation of innate immune responseGO:0045088710.010
cell maturationGO:00484691440.010
polyol biosynthetic processGO:004617330.010
establishment or maintenance of cytoskeleton polarityGO:0030952440.010
exocrine system developmentGO:00352721620.010
muscle organ developmentGO:00075171270.010
nucleoside triphosphate metabolic processGO:00091411200.010
regulation of sterol transportGO:003237110.010
regulation of neurogenesisGO:00507671580.010
neuromuscular synaptic transmissionGO:0007274670.010
rna processingGO:00063961470.010
neurotransmitter metabolic processGO:004213320.010
glycosyl compound metabolic processGO:19016571270.010
adult locomotory behaviorGO:0008344760.010
meiotic cell cycleGO:00513211710.010
ribonucleotide metabolic processGO:00092591450.010
phosphatidic acid metabolic processGO:004647310.010
regulation of gene silencingGO:0060968630.010

Twdlalpha disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.039
nervous system diseaseDOID:86300.017
disease of metabolismDOID:001466700.015
inherited metabolic disorderDOID:65500.015
cardiovascular system diseaseDOID:128700.012
sensory system diseaseDOID:005015500.010
diabetes mellitusDOID:935100.010
glucose metabolism diseaseDOID:419400.010
carbohydrate metabolism diseaseDOID:005001300.010
type 2 diabetes mellitusDOID:935200.010
acquired metabolic diseaseDOID:006015800.010