Drosophila melanogaster

65 known processes

spz5 (Dmel_CG9972)

spatzle 5

(Aliases: DNT2,Dmel\CG9972,NT2,CG9972,Spz5,CT28115)

spz5 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
taxisGO:00423303040.329
motor neuron axon guidanceGO:0008045580.305
neuron projection guidanceGO:00974852410.259
axon developmentGO:00615642970.206
chemotaxisGO:00069352490.157
axonogenesisGO:00074092900.154
axon guidanceGO:00074112330.119
appendage morphogenesisGO:00351073970.101
negative regulation of macromolecule biosynthetic processGO:00105582700.099
organophosphate metabolic processGO:00196371950.083
small molecule metabolic processGO:00442813050.077
negative regulation of nitrogen compound metabolic processGO:00511722650.074
organonitrogen compound metabolic processGO:19015643180.073
regulation of nervous system developmentGO:00519602480.070
post embryonic appendage morphogenesisGO:00351203850.069
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.066
eye developmentGO:00016543230.066
negative regulation of rna metabolic processGO:00512532510.062
regulation of protein metabolic processGO:00512462560.059
negative regulation of cellular metabolic processGO:00313243820.058
negative regulation of biosynthetic processGO:00098902770.057
rho protein signal transductionGO:0007266140.052
positive regulation of signal transductionGO:00099672230.051
defense responseGO:00069523000.051
imaginal disc derived appendage developmentGO:00487373990.050
actin cytoskeleton organizationGO:00300362060.050
negative regulation of transcription dna templatedGO:00458922370.049
positive regulation of cell migrationGO:003033520.048
imaginal disc derived appendage morphogenesisGO:00351143950.048
positive regulation of signalingGO:00230562430.048
cell migrationGO:00164772380.048
intracellular signal transductionGO:00355563000.048
imaginal disc derived wing morphogenesisGO:00074763370.047
positive regulation of response to stimulusGO:00485843230.047
vesicle mediated transportGO:00161923810.047
positive regulation of nitrogen compound metabolic processGO:00511733540.046
nucleotide metabolic processGO:00091171610.046
response to lipopolysaccharideGO:003249640.043
nucleobase containing small molecule metabolic processGO:00550861740.043
positive regulation of biosynthetic processGO:00098913160.042
regulation of cell cycleGO:00517262910.042
growthGO:00400073590.041
negative regulation of cellular biosynthetic processGO:00313272770.041
cell cycle phase transitionGO:00447701400.041
response to external biotic stimulusGO:00432072930.040
regulation of small gtpase mediated signal transductionGO:0051056930.040
regulation of dendrite morphogenesisGO:0048814280.040
appendage developmentGO:00487364010.040
positive regulation of cell motilityGO:200014730.039
positive regulation of cell communicationGO:00106472500.039
organic substance catabolic processGO:19015753080.039
negative regulation of cell cycleGO:00457861160.039
cell deathGO:00082192790.038
endocytosisGO:00068973100.038
forebrain developmentGO:003090020.038
negative regulation of cell cycle processGO:00109481090.037
telencephalon developmentGO:002153720.037
defense response to other organismGO:00985422250.037
regulation of response to stressGO:00801342000.037
single organism catabolic processGO:00447122280.037
regulation of multicellular organismal developmentGO:20000264140.036
negative regulation of developmental processGO:00510932010.036
regulation of intracellular signal transductionGO:19025312360.036
camera type eye developmentGO:004301040.036
body morphogenesisGO:001017120.035
dendrite morphogenesisGO:00488131990.035
carbohydrate derivative metabolic processGO:19011352170.034
regulation of cell cycle phase transitionGO:19019871300.034
regulation of anatomical structure morphogenesisGO:00226032420.034
phosphorylationGO:00163102940.033
guanosine containing compound metabolic processGO:1901068740.033
nucleoside phosphate metabolic processGO:00067531620.033
negative regulation of gene expressionGO:00106293870.033
ras protein signal transductionGO:0007265880.033
response to bacteriumGO:00096171980.033
amine metabolic processGO:0009308120.032
positive regulation of gene expressionGO:00106282900.032
cell cycle checkpointGO:0000075950.032
regulation of cell developmentGO:00602842150.032
defense response to bacteriumGO:00427421780.032
response to abiotic stimulusGO:00096283410.032
embryo development ending in birth or egg hatchingGO:00097921520.031
localization of cellGO:00516742570.031
regulation of cell morphogenesis involved in differentiationGO:0010769610.030
epithelial cell differentiationGO:00308553220.030
wing disc morphogenesisGO:00074723440.030
negative regulation of mitotic cell cycleGO:00459301090.030
ribonucleoside catabolic processGO:00424541120.029
regulation of cellular component sizeGO:0032535980.029
compound eye developmentGO:00487493070.029
regulation of cellular protein metabolic processGO:00322682430.029
purine ribonucleoside catabolic processGO:00461301120.029
innate immune responseGO:00450871440.029
catabolic processGO:00090564090.029
small gtpase mediated signal transductionGO:0007264880.029
negative regulation of nucleic acid templated transcriptionGO:19035072400.029
positive regulation of macromolecule biosynthetic processGO:00105572830.029
digestive system developmentGO:00551231490.029
tube morphogenesisGO:00352391910.029
cellular protein modification processGO:00064644380.028
negative regulation of nucleobase containing compound metabolic processGO:00459342610.028
synaptic transmissionGO:00072682880.028
positive regulation of rho gtpase activityGO:0032321190.028
purine nucleoside metabolic processGO:00422781270.028
positive regulation of nucleobase containing compound metabolic processGO:00459353320.028
regulation of cell cycle processGO:00105641810.027
phagocytosisGO:00069092150.027
response to other organismGO:00517072930.027
positive regulation of phosphate metabolic processGO:00459371390.027
regulation of cell shapeGO:00083601130.027
negative regulation of multicellular organismal processGO:00512411420.027
single organismal cell cell adhesionGO:0016337450.027
protein modification processGO:00362114380.027
purine ribonucleoside triphosphate metabolic processGO:00092051190.027
negative regulation of response to stimulusGO:00485852580.026
notch signaling pathwayGO:00072191200.026
regulation of transcription from rna polymerase ii promoterGO:00063573780.026
deathGO:00162652840.026
regulation of cellular catabolic processGO:00313291570.026
embryonic development via the syncytial blastodermGO:00017001480.026
ribose phosphate metabolic processGO:00196931450.026
humoral immune responseGO:00069591170.026
somatic muscle developmentGO:0007525660.026
nuclear divisionGO:00002803320.025
regulation of mitotic cell cycleGO:00073461900.025
immune responseGO:00069552460.025
regulation of localizationGO:00328792750.025
negative regulation of growthGO:0045926840.025
negative regulation of mitotic cell cycle phase transitionGO:19019911030.025
intracellular transportGO:00469072280.025
regulation of cellular amino acid metabolic processGO:000652100.025
mapk cascadeGO:00001651070.025
organonitrogen compound catabolic processGO:19015651280.025
response to biotic stimulusGO:00096072940.025
carbohydrate derivative catabolic processGO:19011361180.025
negative regulation of nervous system developmentGO:0051961920.025
response to organic substanceGO:00100332840.025
cell proliferationGO:00082832990.024
mitotic cell cycle phase transitionGO:00447721380.024
dendrite developmentGO:00163582040.024
extracellular structure organizationGO:0043062460.024
negative regulation of developmental growthGO:0048640640.024
single organism behaviorGO:00447083910.024
purine nucleoside catabolic processGO:00061521120.024
negative regulation of cell cycle phase transitionGO:19019881030.024
regulation of axonogenesisGO:0050770320.024
glycosyl compound metabolic processGO:19016571270.024
regulation of cell morphogenesisGO:00226041630.024
organic acid metabolic processGO:00060821030.024
heterocycle catabolic processGO:00467001660.024
central nervous system developmentGO:00074172010.024
regulation of cell differentiationGO:00455953020.023
transcription from rna polymerase ii promoterGO:00063663680.023
regulation of neuron differentiationGO:00456641030.023
purine ribonucleoside triphosphate catabolic processGO:00092071080.023
positive regulation of cellular biosynthetic processGO:00313283160.023
nucleoside catabolic processGO:00091641120.023
regulation of catalytic activityGO:00507901850.023
macromolecular complex assemblyGO:00650032560.023
immune response regulating signaling pathwayGO:000276420.023
purine containing compound catabolic processGO:00725231120.023
regulation of growthGO:00400082330.023
regulation of neurogenesisGO:00507671580.023
regulation of ras protein signal transductionGO:0046578930.023
regionalizationGO:00030024160.022
epithelium migrationGO:00901321480.022
regulation of mitotic cell cycle phase transitionGO:19019901300.022
nucleoside triphosphate metabolic processGO:00091411200.022
regulation of catabolic processGO:00098941700.022
cell cell signaling involved in cell fate commitmentGO:00451682100.022
nucleoside metabolic processGO:00091161270.022
cell divisionGO:00513012480.022
ribonucleotide metabolic processGO:00092591450.022
cellular amine metabolic processGO:0044106120.022
posttranscriptional regulation of gene expressionGO:00106081450.022
regulation of rho gtpase activityGO:0032319200.022
organic cyclic compound catabolic processGO:19013611680.022
regulation of immune system processGO:00026821760.022
purine nucleoside triphosphate metabolic processGO:00091441190.022
programmed cell deathGO:00125012570.022
regulation of anatomical structure sizeGO:00900661630.021
cellular response to molecule of bacterial originGO:007121930.021
guanosine containing compound catabolic processGO:1901069740.021
adult locomotory behaviorGO:0008344760.021
digestive tract developmentGO:00485651490.021
negative regulation of cellular protein metabolic processGO:0032269850.021
negative regulation of signal transductionGO:00099682060.021
purine nucleotide catabolic processGO:00061951090.021
positive regulation of macromolecule metabolic processGO:00106044050.021
meiotic cell cycleGO:00513211710.021
dephosphorylationGO:0016311510.021
response to organophosphorusGO:004668320.021
defense response to gram negative bacteriumGO:0050829940.020
mitotic cell cycle checkpointGO:0007093880.020
respiratory system developmentGO:00605412130.020
regulation of i kappab kinase nf kappab signalingGO:004312220.020
ribonucleoside triphosphate metabolic processGO:00091991190.020
nucleotide catabolic processGO:00091661090.020
aromatic compound catabolic processGO:00194391660.020
lateral inhibitionGO:00463312060.020
ribonucleoside metabolic processGO:00091191270.020
immune response activating signal transductionGO:000275720.020
positive regulation of cellular amine metabolic processGO:003324000.020
regulation of notch signaling pathwayGO:00085931000.020
purine ribonucleotide catabolic processGO:00091541090.020
positive regulation of nucleic acid templated transcriptionGO:19035082660.020
regulation of phosphorus metabolic processGO:00511742100.020
carboxylic acid metabolic processGO:0019752920.020
adult behaviorGO:00305341370.020
positive regulation of transcription dna templatedGO:00458932660.020
muscle cell differentiationGO:00426921030.020
positive regulation of cellular protein metabolic processGO:00322701180.019
developmental growthGO:00485892800.019
positive regulation of rna biosynthetic processGO:19026802660.019
regulation of mapk cascadeGO:0043408920.019
meiotic nuclear divisionGO:00071261510.019
purine ribonucleoside metabolic processGO:00461281270.019
muscle structure developmentGO:00610612240.019
purine ribonucleotide metabolic processGO:00091501450.019
positive regulation of multicellular organismal processGO:00512401430.019
regulation of cellular response to stressGO:0080135890.019
purine nucleotide metabolic processGO:00061631460.019
chaeta developmentGO:0022416970.019
organelle assemblyGO:00709251980.019
negative regulation of cell differentiationGO:00455961430.019
negative regulation of neurogenesisGO:0050768530.019
regulation of cell sizeGO:0008361630.019
regulation of cell projection organizationGO:0031344920.019
columnar cuboidal epithelial cell differentiationGO:00020652560.019
organelle fissionGO:00482853400.019
macromolecule catabolic processGO:00090571610.019
positive regulation of catalytic activityGO:00430851180.018
ameboidal type cell migrationGO:00016671510.018
purine containing compound metabolic processGO:00725211550.018
hormone catabolic processGO:004244730.018
cell adhesionGO:00071551360.018
cellular response to lipopolysaccharideGO:007122230.018
regulation of cellular amine metabolic processGO:003323830.018
epithelial cell developmentGO:00020642740.018
ribonucleotide catabolic processGO:00092611090.018
erbb signaling pathwayGO:0038127580.018
mesenchymal cell differentiationGO:004876210.018
gtp metabolic processGO:0046039720.018
developmental maturationGO:00217001720.018
cell recognitionGO:00080371020.018
gtp catabolic processGO:0006184720.018
response to oxygen containing compoundGO:19017002000.018
oxoacid metabolic processGO:00434361030.018
extracellular matrix assemblyGO:0085029130.018
glycosyl compound catabolic processGO:19016581120.018
actin filament organizationGO:00070151260.018
ethanolamine containing compound metabolic processGO:004243940.017
retina development in camera type eyeGO:006004140.017
kidney developmentGO:000182230.017
synaptic target recognitionGO:0008039450.017
positive regulation of developmental processGO:00510941430.017
connective tissue developmentGO:006144830.017
regulation of neuron projection developmentGO:0010975690.017
actin filament based processGO:00300292200.017
drinking behaviorGO:004275620.017
immune effector processGO:0002252980.017
tissue migrationGO:00901301550.017
regulation of defense responseGO:00313471020.017
regulation of rho protein signal transductionGO:0035023200.017
establishment of localization in cellGO:00516494020.017
neuron recognitionGO:00080381010.016
limb developmentGO:006017310.016
regulation of synapse assemblyGO:0051963940.016
regulation of organelle organizationGO:00330431960.016
benzene containing compound metabolic processGO:004253730.016
xenobiotic catabolic processGO:004217810.016
pattern recognition receptor signaling pathwayGO:000222120.016
apoptotic processGO:00069151590.016
response to radiationGO:00093141550.016
synapse assemblyGO:00074161430.016
negative regulation of cell communicationGO:00106482230.016
regulation of cellular ketone metabolic processGO:001056530.016
exocrine system developmentGO:00352721620.016
cellular ketone metabolic processGO:0042180240.016
cellular response to ethanolGO:007136140.016
cellular response to dna damage stimulusGO:00069742230.016
signal transduction by phosphorylationGO:00230141070.016
phosphatidylinositol mediated signalingGO:004801540.016
regulation of phosphate metabolic processGO:00192202100.016
positive regulation of nervous system developmentGO:0051962690.015
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.015
steroid catabolic processGO:000670610.015
regulation of axon extension involved in axon guidanceGO:004884140.015
eye morphogenesisGO:00485922600.015
mesenchymal cell developmentGO:001403110.015
stress activated mapk cascadeGO:0051403520.015
regulation of response to external stimulusGO:00321011150.015
regulation of molecular functionGO:00650092170.015
gastrulationGO:0007369700.015
estrogen metabolic processGO:000821010.015
regulation of purine nucleotide catabolic processGO:0033121480.015
regulation of cytoskeleton organizationGO:0051493890.015
regulation of developmental growthGO:00486381740.015
open tracheal system developmentGO:00074242040.015
innate immune response activating signal transductionGO:000275820.015
nucleobase containing compound catabolic processGO:00346551650.015
positive regulation of gtp catabolic processGO:0033126430.015
cellular nitrogen compound catabolic processGO:00442701650.015
cell motilityGO:00488702510.015
secondary metabolic processGO:0019748750.015
protein catabolic processGO:00301631010.015
response to organic cyclic compoundGO:0014070890.015
segmentationGO:00352822070.015
positive regulation of intracellular signal transductionGO:19025331160.015
spindle organizationGO:00070512530.015
positive regulation of mapk cascadeGO:0043410630.015
positive regulation of purine nucleotide metabolic processGO:1900544550.015
chaeta morphogenesisGO:0008407420.015
embryonic morphogenesisGO:00485982060.015
organic hydroxy compound metabolic processGO:1901615830.015
gland developmentGO:00487321910.015
organic substance transportGO:00717022570.015
regulation of programmed cell deathGO:00430671520.015
single organism cell adhesionGO:0098602470.014
positive regulation of transportGO:0051050920.014
positive regulation of i kappab kinase nf kappab signalingGO:004312310.014
regulation of cellular localizationGO:00603411360.014
proteolysisGO:00065081920.014
cellular catabolic processGO:00442483720.014
chromosome segregationGO:00070591570.014
regulation of intracellular transportGO:0032386640.014
negative regulation of phosphorus metabolic processGO:0010563450.014
positive regulation of developmental growthGO:0048639620.014
response to light stimulusGO:00094161240.014
multi multicellular organism processGO:00447061230.014
single organism cellular localizationGO:19025801800.014
negative regulation of cellular component organizationGO:00511291080.014
positive regulation of cellular catabolic processGO:0031331950.014
positive regulation of rna metabolic processGO:00512542710.014
lipopolysaccharide mediated signaling pathwayGO:003166310.014
defense response to fungusGO:0050832480.014
protein complex assemblyGO:00064612000.014
gland morphogenesisGO:00226121450.014
regulation of stress activated protein kinase signaling cascadeGO:0070302420.014
peripheral nervous system developmentGO:0007422520.014
regulation of immune effector processGO:0002697520.014
single organism intracellular transportGO:19025822070.014
negative regulation of signalingGO:00230572190.014
regulation of hydrolase activityGO:0051336970.014
neural retina developmentGO:000340740.013
translationGO:0006412690.013
positive regulation of catabolic processGO:00098961050.013
cell cycle arrestGO:000705040.013
triglyceride biosynthetic processGO:001943220.013
activation of innate immune responseGO:000221840.013
regulation of phosphorylationGO:00423251470.013
nucleoside triphosphate catabolic processGO:00091431080.013
eye antennal disc developmentGO:0035214600.013
positive regulation of molecular functionGO:00440931360.013
mitotic nuclear divisionGO:00070672130.013
regulation of antimicrobial humoral responseGO:0002759500.013
stem cell differentiationGO:00488631170.013
chitin based cuticle developmentGO:0040003490.013
protein complex biogenesisGO:00702712010.013
regulation of nucleotide catabolic processGO:0030811480.013
regulation of nucleoside metabolic processGO:0009118500.013
spindle assemblyGO:0051225800.013
positive regulation of ras gtpase activityGO:0032320360.013
negative regulation of axon extensionGO:003051730.013
regulation of apoptotic processGO:00429811300.013
larval developmentGO:00021641040.013
regulation of cell motilityGO:2000145230.013
intracellular protein transportGO:00068861040.013
regulation of nucleotide metabolic processGO:0006140620.013
multi organism reproductive behaviorGO:00447051210.013
salivary gland developmentGO:00074311620.013
peptide metabolic processGO:0006518800.013
regulation of cell deathGO:00109411730.013
regulation of cellular component biogenesisGO:00440872010.013
regulation of production of molecular mediator of immune responseGO:0002700440.013
cell fate specificationGO:0001708710.013
sterol homeostasisGO:005509240.013
gastrulation involving germ band extensionGO:0010004360.013
dna integrity checkpointGO:0031570810.013
positive regulation of phosphorylationGO:0042327870.013
mitotic sister chromatid segregationGO:0000070870.013
male meiosisGO:0007140520.013
oxidoreduction coenzyme metabolic processGO:000673320.013
hindbrain developmentGO:003090220.013
ion transmembrane transportGO:00342201220.013
extracellular matrix organizationGO:0030198320.013
enzyme linked receptor protein signaling pathwayGO:00071671790.013
jak stat cascadeGO:0007259490.013
cellular macromolecule localizationGO:00707272200.012
organonitrogen compound biosynthetic processGO:19015661170.012
regulation of mrna metabolic processGO:1903311720.012
positive regulation of cellular amino acid metabolic processGO:004576400.012
regulation of epithelial cell proliferationGO:005067840.012
cellular amino acid metabolic processGO:0006520610.012
positive regulation of defense responseGO:0031349590.012
protein modification by small protein conjugation or removalGO:00706471060.012
multi organism behaviorGO:00517051750.012
cytoplasmic transportGO:00164821300.012
tissue morphogenesisGO:00487292970.012
actin filament based movementGO:0030048260.012
protein maturationGO:0051604710.012
mrna processingGO:00063971040.012
agingGO:00075681430.012
regulation of ras gtpase activityGO:0032318380.012
regulation of transportGO:00510491810.012
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.012
reproductive behaviorGO:00190981220.012
inositol lipid mediated signalingGO:004801740.012
cell growthGO:00160491080.012
positive regulation of nucleotide metabolic processGO:0045981550.012
endomembrane system organizationGO:00102561190.012
epithelial cell migrationGO:00106311480.012
salivary gland morphogenesisGO:00074351450.012
phenol containing compound metabolic processGO:0018958570.012
protein phosphorylationGO:00064681690.012
regulation of synapse structure and activityGO:00508031280.012
vitamin biosynthetic processGO:000911010.012
peptide biosynthetic processGO:0043043420.012
biological adhesionGO:00226101380.012
acylglycerol catabolic processGO:004646430.012
establishment of organelle localizationGO:00516561220.012
cellular response to biotic stimulusGO:007121640.012
positive regulation of hydrolase activityGO:0051345780.012
regulation of gtp catabolic processGO:0033124440.012
camera type eye morphogenesisGO:004859320.012
rna localizationGO:00064031150.012
matingGO:00076181200.012
segment specificationGO:0007379330.011
positive regulation of protein transportGO:0051222370.011
tube developmentGO:00352952440.011
negative regulation of rna biosynthetic processGO:19026792400.011
cuticle developmentGO:0042335860.011
dorsal ventral axis specificationGO:0009950660.011
regulation of intracellular protein transportGO:0033157460.011
rna processingGO:00063961470.011
protein processingGO:0016485680.011
multicellular organismal reproductive behaviorGO:00330571100.011
regulation of stress activated mapk cascadeGO:0032872410.011
regulation of innate immune responseGO:0045088710.011
protein transportGO:00150311550.011
regulation of extracellular matrix organizationGO:190305340.011
pyridine containing compound metabolic processGO:007252430.011
limb morphogenesisGO:003510810.011
neurological system processGO:00508773580.011
response to fungusGO:0009620500.011
negative regulation of cell developmentGO:0010721620.011
positive regulation of axonogenesisGO:005077220.011
peptidyl amino acid modificationGO:00181931050.011
synapse organizationGO:00508081960.011
negative regulation of protein metabolic processGO:0051248850.011
synaptic growth at neuromuscular junctionGO:00511241190.011
gastrulation with mouth forming firstGO:0001703360.011
nucleoside phosphate catabolic processGO:19012921100.011
l amino acid importGO:004309220.011
lipid metabolic processGO:00066291210.011
peptidyl threonine phosphorylationGO:001810720.011
fat soluble vitamin metabolic processGO:000677510.011
endoderm formationGO:000170630.011
kidney epithelium developmentGO:007207330.011
positive regulation of neuron apoptotic processGO:004352510.011
production of molecular mediator of immune responseGO:0002440460.011
cholesterol homeostasisGO:004263230.010
cellular component assembly involved in morphogenesisGO:00109271510.010
vitamin metabolic processGO:000676620.010
regulation of mitosisGO:0007088560.010
androgen metabolic processGO:000820910.010
single organism carbohydrate metabolic processGO:0044723720.010
neutral lipid catabolic processGO:004646130.010
regulation of establishment of protein localizationGO:0070201610.010
leg disc developmentGO:0035218920.010
organophosphate catabolic processGO:00464341120.010
response to glucoseGO:000974920.010
negative regulation of decapentaplegic signaling pathwayGO:009009940.010
positive regulation of response to external stimulusGO:0032103440.010
regulation of response to dna damage stimulusGO:2001020230.010
protein localizationGO:00081042840.010
regulation of multi organism processGO:00439001310.010
positive regulation of purine nucleotide catabolic processGO:0033123460.010

spz5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.068
nervous system diseaseDOID:86300.021
sensory system diseaseDOID:005015500.021
eye and adnexa diseaseDOID:149200.021
eye diseaseDOID:561400.017
cardiovascular system diseaseDOID:128700.016
musculoskeletal system diseaseDOID:1700.014
vascular diseaseDOID:17800.013
disease of cellular proliferationDOID:1456600.013
cancerDOID:16200.013
artery diseaseDOID:005082800.012
essential hypertensionDOID:1082500.012
hypertensionDOID:1076300.012
disease of metabolismDOID:001466700.011
inherited metabolic disorderDOID:65500.011
connective tissue diseaseDOID:6500.011
bone diseaseDOID:008000100.011