Drosophila melanogaster

24 known processes

Orc4 (Dmel_CG2917)

Origin recognition complex subunit 4

(Aliases: Dmel\CG2917,ORC4,ORC,DmORC4,CG2917,orc4,rDmORC)

Orc4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna metabolic processGO:00062592270.229
dna conformation changeGO:00711031050.183
organelle fissionGO:00482853400.179
regulation of nervous system developmentGO:00519602480.170
regulation of developmental growthGO:00486381740.155
cellular response to dna damage stimulusGO:00069742230.136
cellular catabolic processGO:00442483720.133
meiosis iGO:0007127590.129
catabolic processGO:00090564090.127
regulation of cell cycle phase transitionGO:19019871300.115
negative regulation of gene expressionGO:00106293870.110
cellular macromolecule catabolic processGO:00442651360.105
negative regulation of developmental processGO:00510932010.095
negative regulation of rna metabolic processGO:00512532510.094
organic substance catabolic processGO:19015753080.082
reciprocal dna recombinationGO:0035825190.079
nucleobase containing compound catabolic processGO:00346551650.076
nuclear divisionGO:00002803320.073
organic cyclic compound catabolic processGO:19013611680.067
dna packagingGO:0006323910.065
regulation of anatomical structure morphogenesisGO:00226032420.064
mitotic cytokinesisGO:0000281500.064
regulation of molecular functionGO:00650092170.063
heterocycle catabolic processGO:00467001660.060
cell deathGO:00082192790.058
cytoskeleton dependent cytokinesisGO:0061640810.058
positive regulation of macromolecule metabolic processGO:00106044050.057
dna repairGO:0006281540.056
regulation of phosphorus metabolic processGO:00511742100.054
organonitrogen compound metabolic processGO:19015643180.054
negative regulation of macromolecule biosynthetic processGO:00105582700.054
columnar cuboidal epithelial cell developmentGO:00020662490.053
small molecule metabolic processGO:00442813050.053
cell proliferationGO:00082832990.053
regulation of multicellular organismal developmentGO:20000264140.052
negative regulation of nucleobase containing compound metabolic processGO:00459342610.051
regulation of double strand break repairGO:200077930.051
negative regulation of cellular component organizationGO:00511291080.050
regulation of cell cycleGO:00517262910.050
deathGO:00162652840.049
chromatin modificationGO:00165681470.049
purine ribonucleoside triphosphate catabolic processGO:00092071080.049
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.049
regulation of cellular component biogenesisGO:00440872010.048
aromatic compound catabolic processGO:00194391660.048
negative regulation of nitrogen compound metabolic processGO:00511722650.048
double strand break repairGO:0006302260.048
negative regulation of multicellular organismal processGO:00512411420.047
dna recombinationGO:0006310320.046
purine ribonucleoside catabolic processGO:00461301120.046
axonogenesisGO:00074092900.046
mitotic nuclear divisionGO:00070672130.046
organonitrogen compound catabolic processGO:19015651280.046
purine nucleoside metabolic processGO:00422781270.046
purine containing compound metabolic processGO:00725211550.045
protein modification processGO:00362114380.045
regulation of mitotic cell cycle phase transitionGO:19019901300.044
establishment of localization in cellGO:00516494020.044
negative regulation of cellular biosynthetic processGO:00313272770.043
regulation of cell differentiationGO:00455953020.042
positive regulation of nucleobase containing compound metabolic processGO:00459353320.041
cellular nitrogen compound catabolic processGO:00442701650.041
heart developmentGO:0007507820.040
negative regulation of transcription dna templatedGO:00458922370.040
regulation of neurogenesisGO:00507671580.040
negative regulation of response to stimulusGO:00485852580.039
regulation of mitotic cell cycleGO:00073461900.039
nucleotide metabolic processGO:00091171610.039
phosphorylationGO:00163102940.038
purine containing compound catabolic processGO:00725231120.038
meiotic cell cycle processGO:19030461320.038
ribose phosphate metabolic processGO:00196931450.038
macromolecule catabolic processGO:00090571610.037
regulation of dna recombinationGO:000001840.037
single organism biosynthetic processGO:00447112060.037
carbohydrate derivative catabolic processGO:19011361180.035
regulation of cell cycle processGO:00105641810.035
positive regulation of nitrogen compound metabolic processGO:00511733540.035
cell cycle phase transitionGO:00447701400.035
modification dependent protein catabolic processGO:0019941780.035
proteolysis involved in cellular protein catabolic processGO:0051603830.034
purine nucleoside triphosphate catabolic processGO:00091461080.034
negative regulation of nucleic acid templated transcriptionGO:19035072400.034
post embryonic appendage morphogenesisGO:00351203850.034
nucleotide catabolic processGO:00091661090.034
negative regulation of nervous system developmentGO:0051961920.033
purine ribonucleoside metabolic processGO:00461281270.033
protein phosphorylationGO:00064681690.033
meiotic cell cycleGO:00513211710.033
mitotic cell cycle phase transitionGO:00447721380.032
positive regulation of molecular functionGO:00440931360.032
axon developmentGO:00615642970.032
ribonucleoside triphosphate metabolic processGO:00091991190.032
negative regulation of biosynthetic processGO:00098902770.031
protein catabolic processGO:00301631010.031
protein dna complex assemblyGO:0065004630.031
chromatin remodelingGO:0006338720.031
meiotic dna double strand break formation involved in reciprocal meiotic recombinationGO:001078010.030
single organism catabolic processGO:00447122280.030
nucleoside triphosphate metabolic processGO:00091411200.030
ribonucleoside catabolic processGO:00424541120.030
spindle organizationGO:00070512530.029
reciprocal meiotic recombinationGO:0007131190.029
response to organic substanceGO:00100332840.029
positive regulation of gene expressionGO:00106282900.029
double strand break repair via nonhomologous end joiningGO:000630350.029
ubiquitin dependent protein catabolic processGO:0006511780.029
regulation of gene silencingGO:0060968630.029
positive regulation of biosynthetic processGO:00098913160.028
establishment or maintenance of cell polarityGO:00071631670.028
nucleoside catabolic processGO:00091641120.028
carbohydrate derivative metabolic processGO:19011352170.028
transcription from rna polymerase ii promoterGO:00063663680.028
regulation of transcription from rna polymerase ii promoterGO:00063573780.028
mitotic cell cycle embryonicGO:0045448380.028
developmental growthGO:00485892800.028
apoptotic processGO:00069151590.027
proteolysisGO:00065081920.027
organophosphate metabolic processGO:00196371950.027
spermatogenesisGO:00072832000.026
camera type eye developmentGO:004301040.026
vesicle mediated transportGO:00161923810.026
neurological system processGO:00508773580.026
regulation of catabolic processGO:00098941700.026
cellular protein modification processGO:00064644380.026
segmentationGO:00352822070.026
nucleobase containing small molecule metabolic processGO:00550861740.026
positive regulation of macromolecule biosynthetic processGO:00105572830.026
mitotic spindle organizationGO:00070522200.025
purine nucleotide catabolic processGO:00061951090.025
appendage morphogenesisGO:00351073970.025
nucleoside phosphate metabolic processGO:00067531620.025
chromatin organizationGO:00063252070.024
nucleoside metabolic processGO:00091161270.024
nucleoside phosphate catabolic processGO:19012921100.024
ribonucleotide catabolic processGO:00092611090.024
dna replicationGO:0006260480.024
appendage developmentGO:00487364010.024
eye developmentGO:00016543230.024
mrna metabolic processGO:00160711240.023
regulation of chromosome organizationGO:0033044640.023
microtubule cytoskeleton organization involved in mitosisGO:1902850520.022
regulation of catalytic activityGO:00507901850.022
negative regulation of mitotic cell cycleGO:00459301090.022
cell divisionGO:00513012480.022
centrosome organizationGO:00512971630.022
negative regulation of growthGO:0045926840.022
central nervous system developmentGO:00074172010.022
negative regulation of mitotic cell cycle phase transitionGO:19019911030.022
ribonucleoside metabolic processGO:00091191270.022
negative regulation of organelle organizationGO:0010639560.022
dna duplex unwindingGO:0032508160.022
response to abiotic stimulusGO:00096283410.021
g1 s transition of mitotic cell cycleGO:0000082310.021
purine ribonucleoside triphosphate metabolic processGO:00092051190.021
gene silencingGO:00164581380.021
gliogenesisGO:0042063800.021
positive regulation of phosphate metabolic processGO:00459371390.020
purine ribonucleotide metabolic processGO:00091501450.020
positive regulation of catalytic activityGO:00430851180.020
purine ribonucleotide catabolic processGO:00091541090.020
chromosome segregationGO:00070591570.019
organelle assemblyGO:00709251980.019
cellular macromolecular complex assemblyGO:00346221530.019
positive regulation of transcription dna templatedGO:00458932660.019
mrna processingGO:00063971040.019
ribonucleotide metabolic processGO:00092591450.019
regulation of organelle organizationGO:00330431960.019
oxoacid metabolic processGO:00434361030.018
positive regulation of catabolic processGO:00098961050.018
regulation of phosphate metabolic processGO:00192202100.018
positive regulation of purine nucleotide catabolic processGO:0033123460.018
purine nucleoside triphosphate metabolic processGO:00091441190.018
nucleoside triphosphate catabolic processGO:00091431080.018
response to other organismGO:00517072930.017
spindle assemblyGO:0051225800.017
negative regulation of rna biosynthetic processGO:19026792400.017
negative regulation of developmental growthGO:0048640640.017
body morphogenesisGO:001017120.017
macromolecular complex assemblyGO:00650032560.017
columnar cuboidal epithelial cell differentiationGO:00020652560.017
cellular protein localizationGO:00346131600.017
glycosyl compound catabolic processGO:19016581120.017
positive regulation of phosphorus metabolic processGO:00105621390.017
ribonucleoside triphosphate catabolic processGO:00092031080.017
regulation of cell developmentGO:00602842150.017
positive regulation of cellular biosynthetic processGO:00313283160.017
purine nucleotide metabolic processGO:00061631460.017
blastoderm segmentationGO:00073501590.017
phagocytosisGO:00069092150.017
regulation of protein depolymerizationGO:1901879270.017
glycosyl compound metabolic processGO:19016571270.016
regulation of cell divisionGO:0051302720.016
spindle assembly involved in mitosisGO:0090307500.016
regulation of hydrolase activityGO:0051336970.016
dna damage checkpointGO:0000077780.016
response to bacteriumGO:00096171980.015
negative regulation of microtubule depolymerizationGO:0007026210.015
positive regulation of cell communicationGO:00106472500.015
imaginal disc derived wing morphogenesisGO:00074763370.015
establishment of organelle localizationGO:00516561220.015
cell cycle g1 s phase transitionGO:0044843310.015
regulation of synapse structure and activityGO:00508031280.015
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.015
regulation of growthGO:00400082330.015
response to biotic stimulusGO:00096072940.015
guanosine containing compound catabolic processGO:1901069740.015
compound eye morphogenesisGO:00017452490.015
mitotic g2 dna damage checkpointGO:0007095690.015
regulation of phosphorylationGO:00423251470.015
positive regulation of nucleoside metabolic processGO:0045979470.015
negative regulation of gene expression epigeneticGO:0045814770.014
chromosome condensationGO:0030261410.014
purine nucleoside catabolic processGO:00061521120.014
response to organonitrogen compoundGO:0010243750.014
regulation of cellular catabolic processGO:00313291570.014
response to oxygen containing compoundGO:19017002000.014
sister chromatid segregationGO:0000819920.014
mitotic dna damage checkpointGO:0044773740.014
regulation of mitosisGO:0007088560.014
organic substance transportGO:00717022570.014
nucleoside monophosphate metabolic processGO:0009123520.014
regulation of nucleotide catabolic processGO:0030811480.014
sensory organ morphogenesisGO:00905962600.013
chromosome organizationGO:00512763600.013
cellular macromolecule localizationGO:00707272200.013
positive regulation of nucleic acid templated transcriptionGO:19035082660.013
regulation of nucleotide metabolic processGO:0006140620.013
regulation of cell deathGO:00109411730.013
nuclear dna replicationGO:003326010.013
endocytosisGO:00068973100.013
gtp catabolic processGO:0006184720.013
mitotic g2 m transition checkpointGO:0044818700.013
cellular protein catabolic processGO:0044257830.013
defense response to other organismGO:00985422250.013
positive regulation of cellular catabolic processGO:0031331950.013
chromatin silencingGO:0006342760.013
chromosome separationGO:0051304420.013
response to endogenous stimulusGO:00097191190.013
positive regulation of rna biosynthetic processGO:19026802660.013
regulation of nucleoside metabolic processGO:0009118500.013
regulation of purine nucleotide catabolic processGO:0033121480.013
regulation of synapse organizationGO:00508071100.012
stem cell differentiationGO:00488631170.012
dna biosynthetic processGO:0071897240.012
positive regulation of rna metabolic processGO:00512542710.012
growthGO:00400073590.012
negative regulation of protein depolymerizationGO:1901880230.012
cellular component assembly involved in morphogenesisGO:00109271510.012
sex differentiationGO:0007548810.012
protein localizationGO:00081042840.012
regulation of dna metabolic processGO:0051052340.012
recombinational repairGO:0000725130.012
synapse assemblyGO:00074161430.012
purine ribonucleoside monophosphate metabolic processGO:0009167500.012
notch signaling pathwayGO:00072191200.012
positive regulation of gtpase activityGO:0043547430.012
mitotic dna integrity checkpointGO:0044774750.012
regulation of synapse assemblyGO:0051963940.011
regulation of response to stressGO:00801342000.011
homeostatic processGO:00425921990.011
chromosome localizationGO:0050000200.011
positive regulation of nucleotide metabolic processGO:0045981550.011
wing disc morphogenesisGO:00074723440.011
cellular amino acid metabolic processGO:0006520610.011
centrosome separationGO:0051299200.011
positive regulation of purine nucleotide metabolic processGO:1900544550.011
imaginal disc derived appendage developmentGO:00487373990.011
regulation of purine nucleotide metabolic processGO:1900542620.011
meiotic chromosome segregationGO:0045132590.011
intracellular protein transportGO:00068861040.011
ribonucleoside monophosphate metabolic processGO:0009161510.011
organophosphate catabolic processGO:00464341120.010
mitotic chromosome condensationGO:0007076220.010
dna replication initiationGO:000627060.010
regulation of intracellular signal transductionGO:19025312360.010
programmed cell deathGO:00125012570.010
regulation of gtpase activityGO:0043087440.010
cellular response to nitrogen compoundGO:1901699510.010
g2 dna damage checkpointGO:0031572690.010
regulation of small gtpase mediated signal transductionGO:0051056930.010
immune system processGO:00023763470.010
dna integrity checkpointGO:0031570810.010
regulation of glial cell differentiationGO:004568510.010
small gtpase mediated signal transductionGO:0007264880.010

Orc4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.021
organ system cancerDOID:005068600.021
disease of cellular proliferationDOID:1456600.021
disease of anatomical entityDOID:700.018