IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

CG5645 (Dmel_CG5645)

CG5645 gene product from transcript CG5645-RA

(Aliases: Dmel\CG5645)

FLYBASE: FBgn0036254
Entrez: 39382
UniProtKB: Q9VTU0

Process Predictions
Disease Predictions

CG5645 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.102
response to temperature stimulus	GO:0009266	106	0.089
establishment of organelle localization	GO:0051656	122	0.080
aging	GO:0007568	143	0.079
body morphogenesis	GO:0010171	2	0.077
multicellular organismal reproductive behavior	GO:0033057	110	0.075
macromolecular complex assembly	GO:0065003	256	0.075
negative regulation of gene expression	GO:0010629	387	0.072
regulation of cellular component biogenesis	GO:0044087	201	0.067
catabolic process	GO:0009056	409	0.064
negative regulation of rna biosynthetic process	GO:1902679	240	0.064
tissue morphogenesis	GO:0048729	297	0.062
response to heat	GO:0009408	63	0.060
ribosomal large subunit biogenesis	GO:0042273	1	0.060
single organism catabolic process	GO:0044712	228	0.059
larval development	GO:0002164	104	0.054
organelle fission	GO:0048285	340	0.048
nucleobase containing compound catabolic process	GO:0034655	165	0.045
multicellular organismal aging	GO:0010259	140	0.044
embryo development ending in birth or egg hatching	GO:0009792	152	0.043
organic substance transport	GO:0071702	257	0.042
purine ribonucleoside catabolic process	GO:0046130	112	0.041
establishment of localization in cell	GO:0051649	402	0.041
morphogenesis of an epithelium	GO:0002009	276	0.039
multi multicellular organism process	GO:0044706	123	0.039
negative regulation of biosynthetic process	GO:0009890	277	0.038
actin cytoskeleton organization	GO:0030036	206	0.037
multi organism reproductive behavior	GO:0044705	121	0.037
negative regulation of rna metabolic process	GO:0051253	251	0.037
cell division	GO:0051301	248	0.036
organonitrogen compound metabolic process	GO:1901564	318	0.035
protein complex assembly	GO:0006461	200	0.035
response to abiotic stimulus	GO:0009628	341	0.034
intracellular transport	GO:0046907	228	0.034
reproductive structure development	GO:0048608	74	0.034
regulation of transport	GO:0051049	181	0.033
establishment or maintenance of cell polarity	GO:0007163	167	0.033
sex differentiation	GO:0007548	81	0.033
positive regulation of cell communication	GO:0010647	250	0.032
cellular macromolecular complex assembly	GO:0034622	153	0.032
negative regulation of cellular metabolic process	GO:0031324	382	0.032
organelle localization	GO:0051640	148	0.032
single organism behavior	GO:0044708	391	0.032
response to organic substance	GO:0010033	284	0.032
striated muscle myosin thick filament assembly	GO:0071688	3	0.032
ribonucleotide metabolic process	GO:0009259	145	0.031
protein transport	GO:0015031	155	0.031
negative regulation of transcription dna templated	GO:0045892	237	0.031
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.031
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.030
organelle assembly	GO:0070925	198	0.030
ameboidal type cell migration	GO:0001667	151	0.030
notch signaling pathway	GO:0007219	120	0.030
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.030
telencephalon development	GO:0021537	2	0.030
protein modification process	GO:0036211	438	0.030
mitotic g2 m transition checkpoint	GO:0044818	70	0.029
organic substance catabolic process	GO:1901575	308	0.028
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.028
post embryonic appendage morphogenesis	GO:0035120	385	0.028
chromosome organization	GO:0051276	360	0.028
cellular catabolic process	GO:0044248	372	0.027
regulation of protein metabolic process	GO:0051246	256	0.026
striated muscle cell differentiation	GO:0051146	90	0.026
mitotic g2 dna damage checkpoint	GO:0007095	69	0.026
regulation of cell cycle process	GO:0010564	181	0.025
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.025
cellular protein modification process	GO:0006464	438	0.025
ribonucleoprotein complex subunit organization	GO:0071826	28	0.025
compound eye morphogenesis	GO:0001745	249	0.025
regulation of organelle organization	GO:0033043	196	0.025
protein complex biogenesis	GO:0070271	201	0.024
vesicle mediated transport	GO:0016192	381	0.024
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.024
positive regulation of cellular biosynthetic process	GO:0031328	316	0.024
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.023
response to nutrient levels	GO:0031667	114	0.023
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.023
positive regulation of signaling	GO:0023056	243	0.023
positive regulation of rna metabolic process	GO:0051254	271	0.023
cellular nitrogen compound catabolic process	GO:0044270	165	0.023
nuclear division	GO:0000280	332	0.022
organic cyclic compound catabolic process	GO:1901361	168	0.022
ribonucleoside catabolic process	GO:0042454	112	0.022
reproductive behavior	GO:0019098	122	0.022
determination of adult lifespan	GO:0008340	137	0.022
lateral inhibition	GO:0046331	206	0.022
heterocycle catabolic process	GO:0046700	166	0.021
axon guidance	GO:0007411	233	0.021
protein modification by small protein conjugation or removal	GO:0070647	106	0.021
regulation of molecular function	GO:0065009	217	0.021
immune response	GO:0006955	246	0.021
cellular protein complex assembly	GO:0043623	71	0.020
nucleotide metabolic process	GO:0009117	161	0.020
reproductive system development	GO:0061458	74	0.020
regulation of phosphorus metabolic process	GO:0051174	210	0.020
regulation of cell cycle	GO:0051726	291	0.020
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.020
positive regulation of response to stimulus	GO:0048584	323	0.020
nucleobase containing small molecule metabolic process	GO:0055086	174	0.020
nucleoside catabolic process	GO:0009164	112	0.019
single organism intracellular transport	GO:1902582	207	0.019
protein localization	GO:0008104	284	0.019
digestive system development	GO:0055123	149	0.019
positive regulation of phosphate metabolic process	GO:0045937	139	0.019
regulation of protein modification process	GO:0031399	112	0.019
single organism nuclear import	GO:1902593	51	0.019
regulation of cellular protein metabolic process	GO:0032268	243	0.019
establishment of cell polarity	GO:0030010	40	0.019
endocytosis	GO:0006897	310	0.018
phosphorylation	GO:0016310	294	0.018
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.018
positive regulation of signal transduction	GO:0009967	223	0.018
cellular component assembly involved in morphogenesis	GO:0010927	151	0.018
regulation of alternative mrna splicing via spliceosome	GO:0000381	60	0.018
epithelial cell migration	GO:0010631	148	0.018
response to oxygen containing compound	GO:1901700	200	0.018
phagocytosis	GO:0006909	215	0.018
nuclear transport	GO:0051169	72	0.018
nucleoside triphosphate metabolic process	GO:0009141	120	0.018
regulation of establishment of protein localization	GO:0070201	61	0.018
aromatic compound catabolic process	GO:0019439	166	0.018
purine ribonucleotide metabolic process	GO:0009150	145	0.018
muscle structure development	GO:0061061	224	0.018
regulation of cell differentiation	GO:0045595	302	0.018
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.018
intracellular signal transduction	GO:0035556	300	0.018
locomotory behavior	GO:0007626	176	0.017
multi organism behavior	GO:0051705	175	0.017
ribonucleoside monophosphate metabolic process	GO:0009161	51	0.017
tissue migration	GO:0090130	155	0.017
mrna processing	GO:0006397	104	0.017
rna localization	GO:0006403	115	0.017
nitrogen compound transport	GO:0071705	85	0.017
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.017
ribose phosphate metabolic process	GO:0019693	145	0.017
regulation of catalytic activity	GO:0050790	185	0.017
positive regulation of gene expression	GO:0010628	290	0.016
regulation of response to stress	GO:0080134	200	0.016
negative regulation of cell cycle process	GO:0010948	109	0.016
positive regulation of molecular function	GO:0044093	136	0.016
negative regulation of protein metabolic process	GO:0051248	85	0.016
regulation of protein transport	GO:0051223	57	0.016
regulation of localization	GO:0032879	275	0.016
adult behavior	GO:0030534	137	0.016
gonad development	GO:0008406	50	0.016
positive regulation of multicellular organismal process	GO:0051240	143	0.016
purine nucleotide metabolic process	GO:0006163	146	0.016
establishment of protein localization	GO:0045184	163	0.016
vitamin biosynthetic process	GO:0009110	1	0.016
axon development	GO:0061564	297	0.016
neurological system process	GO:0050877	358	0.016
striated muscle cell development	GO:0055002	50	0.015
regulation of cell division	GO:0051302	72	0.015
axonogenesis	GO:0007409	290	0.015
nucleoside monophosphate metabolic process	GO:0009123	52	0.015
positive regulation of cell motility	GO:2000147	3	0.015
purine nucleoside metabolic process	GO:0042278	127	0.015
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.015
tube development	GO:0035295	244	0.015
purine ribonucleoside monophosphate metabolic process	GO:0009167	50	0.015
mushroom body development	GO:0016319	70	0.015
actin filament based process	GO:0030029	220	0.015
salivary gland development	GO:0007431	162	0.015
negative regulation of cellular protein metabolic process	GO:0032269	85	0.015
intracellular protein transport	GO:0006886	104	0.015
digestive tract development	GO:0048565	149	0.015
regulation of phosphate metabolic process	GO:0019220	210	0.015
protein targeting to nucleus	GO:0044744	51	0.014
response to hypoxia	GO:0001666	53	0.014
protein phosphorylation	GO:0006468	169	0.014
cell migration	GO:0016477	238	0.014
cell proliferation	GO:0008283	299	0.014
microtubule organizing center organization	GO:0031023	168	0.014
regulation of intracellular signal transduction	GO:1902531	236	0.014
cellular amino acid metabolic process	GO:0006520	61	0.014
purine ribonucleotide catabolic process	GO:0009154	109	0.014
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.014
transcription from rna polymerase ii promoter	GO:0006366	368	0.014
cell death	GO:0008219	279	0.014
cytoplasmic transport	GO:0016482	130	0.014
gastrulation	GO:0007369	70	0.014
nuclear import	GO:0051170	51	0.014
cellular macromolecule catabolic process	GO:0044265	136	0.014
rna processing	GO:0006396	147	0.013
negative regulation of cellular biosynthetic process	GO:0031327	277	0.013
atp metabolic process	GO:0046034	49	0.013
innate immune response	GO:0045087	144	0.013
cell motility	GO:0048870	251	0.013
central nervous system development	GO:0007417	201	0.013
response to light stimulus	GO:0009416	124	0.013
macromolecule catabolic process	GO:0009057	161	0.013
death	GO:0016265	284	0.013
regulation of developmental growth	GO:0048638	174	0.013
forebrain development	GO:0030900	2	0.013
developmental programmed cell death	GO:0010623	138	0.013
imaginal disc derived wing morphogenesis	GO:0007476	337	0.013
establishment of planar polarity	GO:0001736	87	0.013
nucleoside phosphate catabolic process	GO:1901292	110	0.013
purine nucleoside monophosphate catabolic process	GO:0009128	38	0.013
kidney development	GO:0001822	3	0.013
nucleoside triphosphate catabolic process	GO:0009143	108	0.013
cytokinesis	GO:0000910	90	0.013
establishment of protein localization to organelle	GO:0072594	62	0.013
tube morphogenesis	GO:0035239	191	0.012
protein import	GO:0017038	55	0.012
single organism cellular localization	GO:1902580	180	0.012
anatomical structure homeostasis	GO:0060249	97	0.012
cognition	GO:0050890	141	0.012
protein import into nucleus	GO:0006606	51	0.012
regulation of anatomical structure morphogenesis	GO:0022603	242	0.012
muscle cell development	GO:0055001	50	0.012
olfactory behavior	GO:0042048	97	0.012
localization of cell	GO:0051674	257	0.012
cellular macromolecule localization	GO:0070727	220	0.012
negative regulation of mitotic cell cycle	GO:0045930	109	0.012
connective tissue development	GO:0061448	3	0.012
ion transport	GO:0006811	145	0.012
carbohydrate derivative metabolic process	GO:1901135	217	0.012
embryonic development via the syncytial blastoderm	GO:0001700	148	0.012
regulation of cell development	GO:0060284	215	0.012
glycosyl compound catabolic process	GO:1901658	112	0.012
stem cell development	GO:0048864	79	0.012
regulation of protein complex assembly	GO:0043254	42	0.012
developmental growth	GO:0048589	280	0.012
regulation of intracellular protein transport	GO:0033157	46	0.012
compound eye development	GO:0048749	307	0.012
appendage morphogenesis	GO:0035107	397	0.012
response to other organism	GO:0051707	293	0.012
chemosensory behavior	GO:0007635	106	0.012
protein catabolic process	GO:0030163	101	0.011
chromosome segregation	GO:0007059	157	0.011
small molecule metabolic process	GO:0044281	305	0.011
regulation of phosphorylation	GO:0042325	147	0.011
ribonucleotide catabolic process	GO:0009261	109	0.011
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.011
gland morphogenesis	GO:0022612	145	0.011
secretion	GO:0046903	109	0.011
negative regulation of signaling	GO:0023057	219	0.011
cell cycle phase transition	GO:0044770	140	0.011
camera type eye development	GO:0043010	4	0.011
nucleoside metabolic process	GO:0009116	127	0.011
programmed cell death	GO:0012501	257	0.011
organonitrogen compound biosynthetic process	GO:1901566	117	0.011
positive regulation of intracellular signal transduction	GO:1902533	116	0.011
open tracheal system development	GO:0007424	204	0.011
positive regulation of macromolecule metabolic process	GO:0010604	405	0.011
chaperone mediated protein folding	GO:0061077	2	0.011
positive regulation of immune system process	GO:0002684	68	0.011
purine containing compound metabolic process	GO:0072521	155	0.011
dendrite development	GO:0016358	204	0.011
regulation of cellular localization	GO:0060341	136	0.011
mitotic dna damage checkpoint	GO:0044773	74	0.011
protein localization to nucleus	GO:0034504	55	0.011
morphogenesis of follicular epithelium	GO:0016333	36	0.011
salivary gland morphogenesis	GO:0007435	145	0.010
organonitrogen compound catabolic process	GO:1901565	128	0.010
chromatin organization	GO:0006325	207	0.010
cell cycle arrest	GO:0007050	4	0.010
negative regulation of cell death	GO:0060548	81	0.010
apoptotic process	GO:0006915	159	0.010
positive regulation of cellular component biogenesis	GO:0044089	80	0.010
chemotaxis	GO:0006935	249	0.010
regulation of nucleocytoplasmic transport	GO:0046822	35	0.010
dna integrity checkpoint	GO:0031570	81	0.010
negative regulation of cellular component organization	GO:0051129	108	0.010

CG5645 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.036
nervous system disease	DOID:863	0.012
disease of cellular proliferation	DOID:14566	0.011

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