Drosophila melanogaster

15 known processes

otp (Dmel_CG10036)

orthopedia

(Aliases: w26,BcDNA:RE58095,CG10036,W26,Otp,bk24,CG2965,Dmel\CG10036)

otp biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
tissue morphogenesisGO:00487292970.056
transcription from rna polymerase ii promoterGO:00063663680.040
camera type eye developmentGO:004301040.038
cell cell signaling involved in cell fate commitmentGO:00451682100.037
tube developmentGO:00352952440.033
vesicle mediated transportGO:00161923810.033
intracellular signal transductionGO:00355563000.032
lateral inhibitionGO:00463312060.031
establishment of localization in cellGO:00516494020.031
protein modification processGO:00362114380.030
regionalizationGO:00030024160.030
protein localizationGO:00081042840.030
cell deathGO:00082192790.029
deathGO:00162652840.029
positive regulation of nitrogen compound metabolic processGO:00511733540.029
phagocytosisGO:00069092150.028
body morphogenesisGO:001017120.028
blastoderm segmentationGO:00073501590.027
morphogenesis of an epitheliumGO:00020092760.026
eye developmentGO:00016543230.026
cell motilityGO:00488702510.026
embryonic pattern specificationGO:00098801740.026
positive regulation of macromolecule metabolic processGO:00106044050.026
negative regulation of gene expressionGO:00106293870.026
segmentationGO:00352822070.026
programmed cell deathGO:00125012570.025
positive regulation of cell communicationGO:00106472500.025
regulation of multicellular organismal developmentGO:20000264140.025
Mouse
organelle fissionGO:00482853400.024
organelle assemblyGO:00709251980.024
catabolic processGO:00090564090.024
epithelial cell differentiationGO:00308553220.024
single organism behaviorGO:00447083910.024
Zebrafish
sensory organ morphogenesisGO:00905962600.024
endocytosisGO:00068973100.024
positive regulation of rna biosynthetic processGO:19026802660.023
organonitrogen compound metabolic processGO:19015643180.023
cellular component assembly involved in morphogenesisGO:00109271510.023
organic substance transportGO:00717022570.023
kidney developmentGO:000182230.023
columnar cuboidal epithelial cell developmentGO:00020662490.023
neurological system processGO:00508773580.023
spindle organizationGO:00070512530.022
cellular amino acid metabolic processGO:0006520610.022
forebrain developmentGO:003090020.022
Zebrafish Mouse
negative regulation of biosynthetic processGO:00098902770.022
nuclear divisionGO:00002803320.022
wing disc morphogenesisGO:00074723440.022
small molecule metabolic processGO:00442813050.022
negative regulation of cellular metabolic processGO:00313243820.021
endomembrane system organizationGO:00102561190.021
cellular catabolic processGO:00442483720.021
cellular protein modification processGO:00064644380.021
small gtpase mediated signal transductionGO:0007264880.021
regulation of cellular protein metabolic processGO:00322682430.021
localization of cellGO:00516742570.021
developmental maturationGO:00217001720.021
regulation of organelle organizationGO:00330431960.021
negative regulation of developmental processGO:00510932010.021
regulation of transcription from rna polymerase ii promoterGO:00063573780.021
regulation of cell deathGO:00109411730.021
imaginal disc derived appendage developmentGO:00487373990.020
positive regulation of nucleobase containing compound metabolic processGO:00459353320.020
regulation of response to stressGO:00801342000.020
intracellular transportGO:00469072280.020
positive regulation of cellular biosynthetic processGO:00313283160.019
regulation of mrna splicing via spliceosomeGO:0048024640.019
positive regulation of rna metabolic processGO:00512542710.019
apoptotic processGO:00069151590.019
cell migrationGO:00164772380.019
eye photoreceptor cell differentiationGO:00017541450.019
positive regulation of macromolecule biosynthetic processGO:00105572830.019
regulation of intracellular signal transductionGO:19025312360.019
cell proliferationGO:00082832990.019
Mouse
regulation of molecular functionGO:00650092170.019
hindbrain developmentGO:003090220.019
organic acid metabolic processGO:00060821030.018
ras protein signal transductionGO:0007265880.018
regulation of cellular amino acid metabolic processGO:000652100.018
positive regulation of nucleic acid templated transcriptionGO:19035082660.018
positive regulation of signalingGO:00230562430.018
respiratory system developmentGO:00605412130.018
positive regulation of phosphorus metabolic processGO:00105621390.018
cellular macromolecule localizationGO:00707272200.018
developmental growthGO:00485892800.018
positive regulation of phosphate metabolic processGO:00459371390.018
regulation of protein metabolic processGO:00512462560.018
regulation of phosphate metabolic processGO:00192202100.018
imaginal disc derived wing morphogenesisGO:00074763370.017
regulation of cellular amine metabolic processGO:003323830.017
regulation of localizationGO:00328792750.017
regulation of transportGO:00510491810.017
positive regulation of response to stimulusGO:00485843230.017
axon developmentGO:00615642970.017
regulation of catalytic activityGO:00507901850.017
negative regulation of nitrogen compound metabolic processGO:00511722650.017
response to biotic stimulusGO:00096072940.017
growthGO:00400073590.017
positive regulation of biosynthetic processGO:00098913160.017
phosphorylationGO:00163102940.017
epithelial cell developmentGO:00020642740.017
appendage morphogenesisGO:00351073970.017
regulation of apoptotic processGO:00429811300.016
notch signaling pathwayGO:00072191200.016
regulation of anatomical structure sizeGO:00900661630.016
mitotic spindle organizationGO:00070522200.016
dorsal ventral pattern formationGO:00099531330.016
imaginal disc derived appendage morphogenesisGO:00351143950.016
connective tissue developmentGO:006144830.016
negative regulation of nucleic acid templated transcriptionGO:19035072400.016
regulation of phosphorus metabolic processGO:00511742100.016
positive regulation of signal transductionGO:00099672230.016
axonogenesisGO:00074092900.016
regulation of anatomical structure morphogenesisGO:00226032420.016
macromolecular complex assemblyGO:00650032560.016
single organism catabolic processGO:00447122280.016
regulation of nervous system developmentGO:00519602480.016
Mouse
carboxylic acid metabolic processGO:0019752920.016
negative regulation of macromolecule biosynthetic processGO:00105582700.016
spermatogenesisGO:00072832000.015
regulation of alternative mrna splicing via spliceosomeGO:0000381600.015
regulation of cellular ketone metabolic processGO:001056530.015
organic cyclic compound catabolic processGO:19013611680.015
heterocycle catabolic processGO:00467001660.015
dendrite morphogenesisGO:00488131990.015
carbohydrate derivative metabolic processGO:19011352170.015
establishment or maintenance of cell polarityGO:00071631670.015
compound eye developmentGO:00487493070.015
nucleobase containing small molecule metabolic processGO:00550861740.015
appendage developmentGO:00487364010.015
retina development in camera type eyeGO:006004140.015
regulation of programmed cell deathGO:00430671520.015
telencephalon developmentGO:002153720.015
rna processingGO:00063961470.015
negative regulation of cell deathGO:0060548810.015
salt aversionGO:003519930.015
dendrite developmentGO:00163582040.015
organic substance catabolic processGO:19015753080.015
negative regulation of nucleobase containing compound metabolic processGO:00459342610.015
positive regulation of gene expressionGO:00106282900.014
post embryonic appendage morphogenesisGO:00351203850.014
response to oxygen containing compoundGO:19017002000.014
cilium organizationGO:0044782410.014
response to monosaccharideGO:003428440.014
single organism intracellular transportGO:19025822070.014
embryonic development via the syncytial blastodermGO:00017001480.014
ameboidal type cell migrationGO:00016671510.014
embryonic morphogenesisGO:00485982060.014
positive regulation of transcription dna templatedGO:00458932660.014
open tracheal system developmentGO:00074242040.014
compound eye photoreceptor cell differentiationGO:00017511400.014
cell projection assemblyGO:0030031940.014
central nervous system developmentGO:00074172010.014
Zebrafish Mouse
tube morphogenesisGO:00352391910.014
sensory perception of chemical stimulusGO:00076061160.014
compound eye morphogenesisGO:00017452490.014
organelle localizationGO:00516401480.014
cell divisionGO:00513012480.014
single organism biosynthetic processGO:00447112060.014
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.014
exocrine system developmentGO:00352721620.014
monocarboxylic acid transportGO:001571830.014
response to organic substanceGO:00100332840.014
oxoacid metabolic processGO:00434361030.013
eye morphogenesisGO:00485922600.013
nucleotide metabolic processGO:00091171610.013
regulation of catabolic processGO:00098941700.013
neuropeptide signaling pathwayGO:0007218450.013
chromosome organizationGO:00512763600.013
cilium assemblyGO:0042384380.013
membrane organizationGO:00610241120.013
negative regulation of rna biosynthetic processGO:19026792400.013
chemotaxisGO:00069352490.013
photoreceptor cell differentiationGO:00465301700.013
establishment of protein localizationGO:00451841630.013
mrna processingGO:00063971040.013
purine ribonucleoside catabolic processGO:00461301120.013
posttranscriptional regulation of gene expressionGO:00106081450.013
salivary gland morphogenesisGO:00074351450.013
response to lipopolysaccharideGO:003249640.013
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.013
regulation of rna splicingGO:0043484690.013
response to abiotic stimulusGO:00096283410.013
Zebrafish
axis specificationGO:00097981670.013
cellular nitrogen compound catabolic processGO:00442701650.013
protein complex assemblyGO:00064612000.013
columnar cuboidal epithelial cell differentiationGO:00020652560.013
digestive system developmentGO:00551231490.013
cilium morphogenesisGO:0060271390.013
rna splicing via transesterification reactionsGO:0000375730.013
regulation of cellular component biogenesisGO:00440872010.013
negative regulation of programmed cell deathGO:0043069720.013
g protein coupled receptor signaling pathwayGO:00071861360.013
meiotic nuclear divisionGO:00071261510.013
epithelial cell migrationGO:00106311480.013
regulation of gene silencingGO:0060968630.013
inter male aggressive behaviorGO:0002121600.013
aromatic compound catabolic processGO:00194391660.013
single organism cellular localizationGO:19025801800.013
regulation of hydrolase activityGO:0051336970.012
digestive tract developmentGO:00485651490.012
amine metabolic processGO:0009308120.012
photoreceptor cell developmentGO:0042461960.012
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377730.012
organophosphate metabolic processGO:00196371950.012
positive regulation of cellular component organizationGO:00511301560.012
nucleoside phosphate catabolic processGO:19012921100.012
negative regulation of rna metabolic processGO:00512532510.012
regulation of cell cycleGO:00517262910.012
wound healingGO:0042060750.012
axon guidanceGO:00074112330.012
tissue migrationGO:00901301550.012
male gamete generationGO:00482322010.012
tripartite regional subdivisionGO:00073511030.012
regulation of cellular catabolic processGO:00313291570.012
meiotic cell cycleGO:00513211710.012
mitotic nuclear divisionGO:00070672130.012
regulation of mrna metabolic processGO:1903311720.012
compound eye photoreceptor developmentGO:0042051780.012
protein heterooligomerizationGO:005129140.012
nucleoside phosphate metabolic processGO:00067531620.012
camera type eye morphogenesisGO:004859320.012
positive regulation of cell migrationGO:003033520.012
alternative mrna splicing via spliceosomeGO:0000380600.012
regulation of mrna processingGO:0050684710.012
cellular protein localizationGO:00346131600.012
positive regulation of molecular functionGO:00440931360.012
protein transportGO:00150311550.012
nucleobase containing compound catabolic processGO:00346551650.012
detection of stimulusGO:00516061560.012
negative regulation of response to stimulusGO:00485852580.012
response to alcoholGO:0097305950.012
mrna splicing via spliceosomeGO:0000398730.012
epithelium migrationGO:00901321480.012
adult behaviorGO:00305341370.012
cellular response to carbohydrate stimulusGO:007132240.012
digestive tract morphogenesisGO:00485461270.012
protein complex biogenesisGO:00702712010.012
rna splicingGO:0008380830.012
golgi organizationGO:0007030660.012
positive regulation of cell motilityGO:200014730.012
actin cytoskeleton organizationGO:00300362060.012
mesenchymal cell developmentGO:001403110.011
salivary gland developmentGO:00074311620.011
eye photoreceptor cell developmentGO:0042462810.011
regulation of ras protein signal transductionGO:0046578930.011
purine containing compound metabolic processGO:00725211550.011
mesenchymal cell differentiationGO:004876210.011
purine nucleoside catabolic processGO:00061521120.011
positive regulation of catabolic processGO:00098961050.011
enzyme linked receptor protein signaling pathwayGO:00071671790.011
cellularizationGO:0007349900.011
cellular response to chemical stimulusGO:00708871990.011
regulation of cell developmentGO:00602842150.011
Mouse
embryonic axis specificationGO:00005781070.011
anterior posterior axis specification embryoGO:00085951030.011
negative regulation of signal transductionGO:00099682060.011
regulation of synapse structure and activityGO:00508031280.011
regulation of cell proliferationGO:00421271630.011
Mouse
neuromuscular synaptic transmissionGO:0007274670.011
developmental cell growthGO:0048588520.011
gland developmentGO:00487321910.011
Mouse
segment specificationGO:0007379330.011
benzene containing compound metabolic processGO:004253730.011
mrna metabolic processGO:00160711240.011
proteolysisGO:00065081920.011
neuron projection guidanceGO:00974852410.011
positive regulation of intracellular signal transductionGO:19025331160.011
secretionGO:00469031090.011
taxisGO:00423303040.011
oocyte differentiationGO:00099941450.011
regulation of mitotic cell cycleGO:00073461900.011
protein phosphorylationGO:00064681690.011
regulation of gene expression epigeneticGO:00400291280.011
gene silencingGO:00164581380.011
cell adhesionGO:00071551360.011
positive regulation of transportGO:0051050920.011
regulation of developmental growthGO:00486381740.011
regulation of cell differentiationGO:00455953020.011
Mouse
response to other organismGO:00517072930.011
positive regulation of phosphorylationGO:0042327870.011
aggressive behaviorGO:0002118630.011
synapse organizationGO:00508081960.011
defense response to gram negative bacteriumGO:0050829940.011
protein dna complex subunit organizationGO:0071824860.011
chemosensory behaviorGO:00076351060.010
muscle structure developmentGO:00610612240.010
cellular amine metabolic processGO:0044106120.010
hindgut morphogenesisGO:0007442580.010
regulation of protein modification processGO:00313991120.010
sensory perceptionGO:00076001960.010
chromatin organizationGO:00063252070.010
macromolecule catabolic processGO:00090571610.010
positive regulation of multicellular organismal processGO:00512401430.010
Mouse
regulation of neurogenesisGO:00507671580.010
Mouse
purine nucleotide metabolic processGO:00061631460.010
leg disc morphogenesisGO:0007478800.010
purine nucleoside triphosphate catabolic processGO:00091461080.010
renal system developmentGO:0072001720.010
defense response to bacteriumGO:00427421780.010
sensory perception of salty tasteGO:005091430.010
eggshell formationGO:00307031050.010
nucleoside triphosphate catabolic processGO:00091431080.010
leg disc developmentGO:0035218920.010
negative regulation of apoptotic processGO:0043066630.010
tissue deathGO:00162711020.010
response to organophosphorusGO:004668320.010
negative regulation of transcription dna templatedGO:00458922370.010
organonitrogen compound catabolic processGO:19015651280.010

otp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.036
nervous system diseaseDOID:86300.015
renal tubular transport diseaseDOID:44700.013
urinary system diseaseDOID:1800.013
kidney diseaseDOID:55700.013
inherited metabolic disorderDOID:65500.013
disease of metabolismDOID:001466700.013
cardiovascular system diseaseDOID:128700.012
musculoskeletal system diseaseDOID:1700.012