IMP: Integrative Multi-species Prediction

Drosophila melanogaster

63 known processes

for (Dmel_CG10033)

foraging

(Aliases: l(2)06860,Dg2,dg2,FOR/PKG,CG10033,Pkg24A,DG2,BcDNA:GM08338,142251_at,Pkg2,PKG,anon-WO02059370.47,Dmel\CG10033,anon-WO0140519.260)

FLYBASE: FBgn0000721
Entrez: 44817
UniProtKB: Q03043
UniProtKB: E1JHR9
UniProtKB: P32023

Process Predictions
Disease Predictions

for biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
single organism behavior	GO:0044708	391	0.988
olfactory behavior	GO:0042048	97	0.907
memory	GO:0007613	94	0.708
chemosensory behavior	GO:0007635	106	0.684
cognition	GO:0050890	141	0.613
protein transport	GO:0015031	155	0.608
regulation of cell differentiation	GO:0045595	302	0.595
regulation of protein metabolic process	GO:0051246	256	0.455
organic substance transport	GO:0071702	257	0.385
neurological system process	GO:0050877	358	0.354
secretion	GO:0046903	109	0.320
long term memory	GO:0007616	62	0.311
learning or memory	GO:0007611	141	0.304
secretion by cell	GO:0032940	101	0.280
cell maturation	GO:0048469	144	0.272
cellular macromolecule localization	GO:0070727	220	0.259
regulation of protein transport	GO:0051223	57	0.258
locomotory behavior	GO:0007626	176	0.237
cell cell junction organization	GO:0045216	55	0.235
glial cell development	GO:0021782	27	0.221
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.216
developmental maturation	GO:0021700	172	0.206
regulation of transport	GO:0051049	181	0.192
cell cell junction assembly	GO:0007043	38	0.191
cell junction organization	GO:0034330	57	0.190
cellular protein modification process	GO:0006464	438	0.187
regulation of cellular localization	GO:0060341	136	0.187
protein localization	GO:0008104	284	0.184
establishment of localization in cell	GO:0051649	402	0.181
glial cell differentiation	GO:0010001	35	0.162
regionalization	GO:0003002	416	0.159
brain development	GO:0007420	120	0.156	Mouse
olfactory learning	GO:0008355	56	0.145
neural precursor cell proliferation	GO:0061351	75	0.130
positive regulation of macromolecule metabolic process	GO:0010604	405	0.128
regulation of response to stress	GO:0080134	200	0.122	Human
cell junction assembly	GO:0034329	42	0.113
establishment of protein localization	GO:0045184	163	0.112
protein targeting to nucleus	GO:0044744	51	0.110
gliogenesis	GO:0042063	80	0.110
regulation of reproductive process	GO:2000241	54	0.104
inter male aggressive behavior	GO:0002121	60	0.104
regulation of secretion	GO:0051046	44	0.100
regulation of intracellular transport	GO:0032386	64	0.100
negative regulation of cellular metabolic process	GO:0031324	382	0.100
single organism cellular localization	GO:1902580	180	0.097
associative learning	GO:0008306	65	0.096
cytoplasmic transport	GO:0016482	130	0.090
transcription from rna polymerase ii promoter	GO:0006366	368	0.088
hemopoiesis	GO:0030097	46	0.088
hematopoietic or lymphoid organ development	GO:0048534	57	0.087
regulation of secretion by cell	GO:1903530	39	0.086
sensory perception of sound	GO:0007605	56	0.086
protein localization to nucleus	GO:0034504	55	0.082
organelle assembly	GO:0070925	198	0.081
gland development	GO:0048732	191	0.080
taxis	GO:0042330	304	0.078
regulation of nucleocytoplasmic transport	GO:0046822	35	0.076
regulation of establishment of protein localization	GO:0070201	61	0.075
vesicle mediated transport	GO:0016192	381	0.074
intracellular transport	GO:0046907	228	0.073
dorsal ventral pattern formation	GO:0009953	133	0.072
cation transport	GO:0006812	110	0.072	Human
protein modification process	GO:0036211	438	0.071
regulation of cytoplasmic transport	GO:1903649	47	0.069
regulation of multi organism process	GO:0043900	131	0.068
immune system development	GO:0002520	57	0.067
oocyte maturation	GO:0001556	3	0.067
regulation of multicellular organismal development	GO:2000026	414	0.065
intracellular protein transport	GO:0006886	104	0.065
adult behavior	GO:0030534	137	0.064
mitotic cell cycle phase transition	GO:0044772	138	0.063
negative regulation of response to stimulus	GO:0048585	258	0.063	Human
response to hypoxia	GO:0001666	53	0.063
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.060
protein localization to organelle	GO:0033365	82	0.058
negative regulation of protein metabolic process	GO:0051248	85	0.055
response to ethanol	GO:0045471	59	0.055
salivary gland morphogenesis	GO:0007435	145	0.054
negative regulation of cellular biosynthetic process	GO:0031327	277	0.053
blastoderm segmentation	GO:0007350	159	0.053
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.052
cellular protein localization	GO:0034613	160	0.051
maintenance of location	GO:0051235	73	0.051
protein modification by small protein conjugation or removal	GO:0070647	106	0.051
protein import	GO:0017038	55	0.050
regulation of protein localization to nucleus	GO:1900180	29	0.049
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.049
regulation of protein localization	GO:0032880	76	0.045
response to decreased oxygen levels	GO:0036293	58	0.044
nucleocytoplasmic transport	GO:0006913	72	0.044
regulation of nurse cell apoptotic process	GO:0045477	9	0.042
head development	GO:0060322	135	0.042	Mouse
immune system process	GO:0002376	347	0.042
regulation of neurogenesis	GO:0050767	158	0.041
cellular component assembly involved in morphogenesis	GO:0010927	151	0.041
muscle structure development	GO:0061061	224	0.040	Fly
oocyte differentiation	GO:0009994	145	0.039
negative regulation of developmental process	GO:0051093	201	0.039
defense response	GO:0006952	300	0.039
morphogenesis of an epithelium	GO:0002009	276	0.039
regulation of lipid storage	GO:0010883	22	0.037
salivary gland development	GO:0007431	162	0.037
regulation of localization	GO:0032879	275	0.036
synaptic transmission	GO:0007268	288	0.036
response to other organism	GO:0051707	293	0.036
multi organism behavior	GO:0051705	175	0.036
regulation of cell cycle	GO:0051726	291	0.036
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.036
negative regulation of rna metabolic process	GO:0051253	251	0.035
circulatory system development	GO:0072359	82	0.034
negative regulation of cellular protein metabolic process	GO:0032269	85	0.034
learning	GO:0007612	75	0.034
striated muscle myosin thick filament assembly	GO:0071688	3	0.033
regulation of response to dna damage stimulus	GO:2001020	23	0.033
response to organonitrogen compound	GO:0010243	75	0.032
tube morphogenesis	GO:0035239	191	0.031
regulation of cell cycle phase transition	GO:1901987	130	0.031
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.031
brain morphogenesis	GO:0048854	16	0.030
response to external biotic stimulus	GO:0043207	293	0.030
oocyte development	GO:0048599	124	0.030
negative regulation of cellular component organization	GO:0051129	108	0.029
homeostatic process	GO:0042592	199	0.028
cellular response to peptide	GO:1901653	28	0.028
response to mechanical stimulus	GO:0009612	28	0.028
response to nitrogen compound	GO:1901698	90	0.028
gland morphogenesis	GO:0022612	145	0.028
tube development	GO:0035295	244	0.027
g1 s transition of mitotic cell cycle	GO:0000082	31	0.027
organelle localization	GO:0051640	148	0.027
phosphorylation	GO:0016310	294	0.027
protein targeting	GO:0006605	64	0.026
positive regulation of protein localization to nucleus	GO:1900182	21	0.025
oocyte axis specification	GO:0007309	108	0.025
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.025
protein import into nucleus	GO:0006606	51	0.024
aggressive behavior	GO:0002118	63	0.024
regulation of protein import into nucleus	GO:0042306	28	0.024
heart development	GO:0007507	82	0.024
wing disc morphogenesis	GO:0007472	344	0.024
determination of adult lifespan	GO:0008340	137	0.024
nitrogen compound transport	GO:0071705	85	0.024
cellular chemical homeostasis	GO:0055082	40	0.023
negative regulation of molecular function	GO:0044092	51	0.023
cell motility	GO:0048870	251	0.022	Mouse
organic substance catabolic process	GO:1901575	308	0.022	Human
central nervous system development	GO:0007417	201	0.021	Mouse
cellular amino acid metabolic process	GO:0006520	61	0.021
regulation of embryonic development	GO:0045995	68	0.021
positive regulation of signaling	GO:0023056	243	0.021
muscle cell differentiation	GO:0042692	103	0.021
negative regulation of cell differentiation	GO:0045596	143	0.021
sensory perception of mechanical stimulus	GO:0050954	72	0.021
cell proliferation	GO:0008283	299	0.021
embryonic pattern specification	GO:0009880	174	0.020
positive regulation of transcription factor import into nucleus	GO:0042993	19	0.020
regulation of catabolic process	GO:0009894	170	0.020	Human
catabolic process	GO:0009056	409	0.020	Human
mitotic g2 m transition checkpoint	GO:0044818	70	0.020
cellular response to hexose stimulus	GO:0071331	1	0.020
regulation of oskar mrna translation	GO:0046011	8	0.020
ion homeostasis	GO:0050801	55	0.020
chorion containing eggshell formation	GO:0007304	105	0.020
negative regulation of intracellular signal transduction	GO:1902532	57	0.019
organ growth	GO:0035265	56	0.019
regulation of protein modification process	GO:0031399	112	0.019
positive regulation of transcription dna templated	GO:0045893	266	0.019
negative regulation of protein modification process	GO:0031400	29	0.018
eggshell formation	GO:0030703	105	0.018
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.018
positive regulation of calcium ion transport	GO:0051928	4	0.018
programmed cell death	GO:0012501	257	0.018
regulation of cellular protein metabolic process	GO:0032268	243	0.017
establishment of organelle localization	GO:0051656	122	0.017
mesenchymal cell differentiation	GO:0048762	1	0.017
response to extracellular stimulus	GO:0009991	116	0.017
chemical homeostasis	GO:0048878	92	0.016
myofibril assembly	GO:0030239	36	0.016
water homeostasis	GO:0030104	3	0.016
oocyte construction	GO:0007308	112	0.016
single organism intracellular transport	GO:1902582	207	0.016
mushroom body development	GO:0016319	70	0.016
posttranscriptional regulation of gene expression	GO:0010608	145	0.016
multicellular organismal aging	GO:0010259	140	0.016
neuron projection guidance	GO:0097485	241	0.016
short term memory	GO:0007614	19	0.016
pole plasm mrna localization	GO:0019094	49	0.016
cellular homeostasis	GO:0019725	80	0.016
cellular response to organonitrogen compound	GO:0071417	36	0.015
positive regulation of rna metabolic process	GO:0051254	271	0.015
neuromuscular synaptic transmission	GO:0007274	67	0.015
regulation of nervous system development	GO:0051960	248	0.015
positive regulation of cellular protein metabolic process	GO:0032270	118	0.015
dephosphorylation	GO:0016311	51	0.015
regulation of cellular response to stress	GO:0080135	89	0.015
intracellular signal transduction	GO:0035556	300	0.015	Mouse
growth	GO:0040007	359	0.015
single organism biosynthetic process	GO:0044711	206	0.015
protein phosphorylation	GO:0006468	169	0.015
positive regulation of transport	GO:0051050	92	0.015
response to bacterium	GO:0009617	198	0.015
cell cycle phase transition	GO:0044770	140	0.014
cranial nerve development	GO:0021545	1	0.014
metal ion transport	GO:0030001	74	0.014	Human
single organism membrane organization	GO:0044802	93	0.014
striated muscle cell development	GO:0055002	50	0.014
golgi organization	GO:0007030	66	0.014
embryonic organ development	GO:0048568	50	0.014
response to wounding	GO:0009611	94	0.014	Human
mesenchymal cell development	GO:0014031	1	0.013
nuclear transport	GO:0051169	72	0.013
appendage morphogenesis	GO:0035107	397	0.013
response to organophosphorus	GO:0046683	2	0.013
nephrocyte differentiation	GO:0061319	12	0.013
negative regulation of gene expression	GO:0010629	387	0.013
negative regulation of signal transduction	GO:0009968	206	0.013
negative regulation of phosphorus metabolic process	GO:0010563	45	0.013
epithelial tube morphogenesis	GO:0060562	88	0.013
endomembrane system organization	GO:0010256	119	0.013
cellular response to dna damage stimulus	GO:0006974	223	0.013
negative regulation of transcription dna templated	GO:0045892	237	0.013
enteroendocrine cell differentiation	GO:0035883	1	0.013
epithelial cell morphogenesis involved in gastrulation	GO:0003381	7	0.012
cell division	GO:0051301	248	0.012
cation homeostasis	GO:0055080	51	0.012
nephron tubule morphogenesis	GO:0072078	3	0.012
sensory organ morphogenesis	GO:0090596	260	0.012
regulation of transcription factor import into nucleus	GO:0042990	22	0.011
negative regulation of neurogenesis	GO:0050768	53	0.011
regulation of proteolysis	GO:0030162	87	0.011
regulation of phosphorus metabolic process	GO:0051174	210	0.011	Human
organophosphate metabolic process	GO:0019637	195	0.011	Human
post embryonic appendage morphogenesis	GO:0035120	385	0.011
multicellular organismal homeostasis	GO:0048871	41	0.011
imaginal disc derived appendage development	GO:0048737	399	0.011
positive regulation of multi organism process	GO:0043902	40	0.011
positive regulation of rna biosynthetic process	GO:1902680	266	0.011
regulation of embryonic pattern specification	GO:1902875	27	0.011
positive regulation of cellular catabolic process	GO:0031331	95	0.010
positive regulation of cellular biosynthetic process	GO:0031328	316	0.010
heterocycle catabolic process	GO:0046700	166	0.010	Human
skeletal muscle fiber development	GO:0048741	3	0.010
signal release	GO:0023061	49	0.010
behavioral response to ethanol	GO:0048149	49	0.010
hematopoietic progenitor cell differentiation	GO:0002244	1	0.010
protein secretion	GO:0009306	45	0.010
regulation of organ morphogenesis	GO:2000027	78	0.010
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.010
regulation of protein targeting	GO:1903533	29	0.010
regulation of nfat protein import into nucleus	GO:0051532	16	0.010
response to endogenous stimulus	GO:0009719	119	0.010
salivary gland histolysis	GO:0035070	88	0.010

for disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability	Func Analog Org
connective tissue disease	DOID:65	0.021
musculoskeletal system disease	DOID:17	0.021
disease of anatomical entity	DOID:7	0.021	Human
disease of cellular proliferation	DOID:14566	0.014
cancer	DOID:162	0.014
organ system cancer	DOID:0050686	0.012
nervous system disease	DOID:863	0.011

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