Drosophila melanogaster

2 known processes

Irp-1B (Dmel_CG6342)

Iron regulatory protein 1B

(Aliases: Dmel\CG6342,C-Acon,IRP-1,cAcon,IRP1,CG6342,144037_at,IRP-1B)

Irp-1B biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular catabolic processGO:00442483720.211
organic substance catabolic processGO:19015753080.199
single organism catabolic processGO:00447122280.192
catabolic processGO:00090564090.190
small molecule metabolic processGO:00442813050.181
Human
organic acid metabolic processGO:00060821030.150
Human
lipid metabolic processGO:00066291210.125
carboxylic acid metabolic processGO:0019752920.087
Human
cellular lipid metabolic processGO:0044255830.083
organonitrogen compound metabolic processGO:19015643180.079
response to external biotic stimulusGO:00432072930.078
acyl coa metabolic processGO:000663730.069
organophosphate metabolic processGO:00196371950.067
lipid catabolic processGO:0016042210.066
oxoacid metabolic processGO:00434361030.065
Human
thioester metabolic processGO:003538330.064
single organism intracellular transportGO:19025822070.062
single organism biosynthetic processGO:00447112060.061
immune system processGO:00023763470.056
monocarboxylic acid metabolic processGO:0032787290.056
negative regulation of cellular metabolic processGO:00313243820.055
cellular lipid catabolic processGO:0044242160.054
cell proliferationGO:00082832990.053
organic substance transportGO:00717022570.051
appendage developmentGO:00487364010.050
establishment of localization in cellGO:00516494020.048
body morphogenesisGO:001017120.045
nucleoside phosphate metabolic processGO:00067531620.041
fatty acid metabolic processGO:0006631200.041
nucleobase containing small molecule metabolic processGO:00550861740.040
positive regulation of macromolecule metabolic processGO:00106044050.038
positive regulation of signalingGO:00230562430.038
negative regulation of biosynthetic processGO:00098902770.037
defense responseGO:00069523000.037
carbohydrate derivative metabolic processGO:19011352170.037
carboxylic acid catabolic processGO:0046395160.035
growthGO:00400073590.033
telencephalon developmentGO:002153720.032
cell deathGO:00082192790.031
ion transportGO:00068111450.031
intracellular transportGO:00469072280.031
imaginal disc derived wing morphogenesisGO:00074763370.031
neutral lipid biosynthetic processGO:004646020.030
macromolecular complex assemblyGO:00650032560.030
transcription from rna polymerase ii promoterGO:00063663680.030
positive regulation of response to stimulusGO:00485843230.029
carbohydrate metabolic processGO:0005975820.028
negative regulation of gene expressionGO:00106293870.028
fatty acid catabolic processGO:000906290.027
cellular nitrogen compound catabolic processGO:00442701650.027
response to bacteriumGO:00096171980.027
positive regulation of rna biosynthetic processGO:19026802660.027
organic acid catabolic processGO:0016054160.027
wing disc morphogenesisGO:00074723440.026
organonitrogen compound catabolic processGO:19015651280.026
defense response to bacteriumGO:00427421780.026
positive regulation of cell communicationGO:00106472500.026
response to other organismGO:00517072930.026
purine containing compound metabolic processGO:00725211550.025
organic cyclic compound catabolic processGO:19013611680.025
response to biotic stimulusGO:00096072940.025
cellular amino acid metabolic processGO:0006520610.024
post embryonic appendage morphogenesisGO:00351203850.024
ribonucleoside metabolic processGO:00091191270.024
protein complex assemblyGO:00064612000.024
forebrain developmentGO:003090020.024
nucleoside metabolic processGO:00091161270.024
oxidation reduction processGO:00551141230.024
protein modification processGO:00362114380.024
glycosyl compound metabolic processGO:19016571270.024
maintenance of locationGO:0051235730.024
response to organic substanceGO:00100332840.023
Rat
hormone catabolic processGO:004244730.023
positive regulation of nitrogen compound metabolic processGO:00511733540.023
appendage morphogenesisGO:00351073970.023
purine nucleotide metabolic processGO:00061631460.023
tube developmentGO:00352952440.023
Fly
mitotic spindle organizationGO:00070522200.023
nucleotide metabolic processGO:00091171610.023
epithelial cell differentiationGO:00308553220.023
purine ribonucleoside metabolic processGO:00461281270.023
lipid storageGO:0019915380.023
negative regulation of cellular biosynthetic processGO:00313272770.023
regulation of cell proliferationGO:00421271630.022
purine nucleoside metabolic processGO:00422781270.022
purine nucleoside monophosphate metabolic processGO:0009126500.022
neurological system processGO:00508773580.021
open tracheal system developmentGO:00074242040.021
response to abiotic stimulusGO:00096283410.021
Rat
regulation of immune system processGO:00026821760.021
ribose phosphate metabolic processGO:00196931450.021
cellular ketone metabolic processGO:0042180240.021
fatty acid beta oxidationGO:000663560.021
monocarboxylic acid catabolic processGO:0072329100.020
carbohydrate derivative biosynthetic processGO:1901137850.020
heterocycle catabolic processGO:00467001660.020
response to starvationGO:0042594970.020
cellular protein modification processGO:00064644380.020
negative regulation of cell communicationGO:00106482230.020
positive regulation of gene expressionGO:00106282900.020
immune responseGO:00069552460.019
purine ribonucleotide metabolic processGO:00091501450.019
regulation of protein metabolic processGO:00512462560.019
programmed cell deathGO:00125012570.019
negative regulation of response to stimulusGO:00485852580.019
single organism carbohydrate metabolic processGO:0044723720.019
organic hydroxy compound metabolic processGO:1901615830.019
head developmentGO:00603221350.019
defense response to other organismGO:00985422250.019
defense response to gram negative bacteriumGO:0050829940.019
deathGO:00162652840.019
steroid metabolic processGO:0008202200.019
central nervous system developmentGO:00074172010.018
nucleobase containing compound catabolic processGO:00346551650.018
neutral lipid catabolic processGO:004646130.018
lipid modificationGO:0030258240.018
cellular hormone metabolic processGO:0034754230.018
response to oxygen containing compoundGO:19017002000.018
Rat
phagocytosisGO:00069092150.018
regulation of apoptotic processGO:00429811300.018
negative regulation of nucleobase containing compound metabolic processGO:00459342610.018
cell migrationGO:00164772380.017
kidney epithelium developmentGO:007207330.017
small molecule catabolic processGO:0044282210.017
regulation of immune responseGO:00507761180.017
negative regulation of signalingGO:00230572190.017
spindle organizationGO:00070512530.017
regulation of localizationGO:00328792750.016
positive regulation of transcription dna templatedGO:00458932660.016
positive regulation of biosynthetic processGO:00098913160.016
amine metabolic processGO:0009308120.016
embryo development ending in birth or egg hatchingGO:00097921520.016
cellular response to chemical stimulusGO:00708871990.016
Rat
positive regulation of signal transductionGO:00099672230.016
regionalizationGO:00030024160.016
cation transportGO:00068121100.016
macromolecule catabolic processGO:00090571610.016
anion homeostasisGO:005508130.016
small molecule biosynthetic processGO:0044283370.016
ameboidal type cell migrationGO:00016671510.016
digestive system developmentGO:00551231490.016
Fly
regulation of cellular ketone metabolic processGO:001056530.016
transmembrane transportGO:00550851390.016
regulation of hormone levelsGO:0010817400.016
negative regulation of nitrogen compound metabolic processGO:00511722650.016
taxisGO:00423303040.015
negative regulation of signal transductionGO:00099682060.015
apoptotic processGO:00069151590.015
positive regulation of lipid metabolic processGO:004583440.015
cytoplasmic transportGO:00164821300.015
protein complex biogenesisGO:00702712010.015
regulation of response to stressGO:00801342000.015
mrna metabolic processGO:00160711240.015
cell motilityGO:00488702510.015
sesquiterpenoid metabolic processGO:000671430.014
response to copper ionGO:004668840.014
acylglycerol biosynthetic processGO:004646320.014
regulation of multi organism processGO:00439001310.014
nucleoside monophosphate metabolic processGO:0009123520.014
vesicle mediated transportGO:00161923810.014
xenobiotic catabolic processGO:004217810.014
intracellular signal transductionGO:00355563000.014
regulation of programmed cell deathGO:00430671520.014
single organism cellular localizationGO:19025801800.014
neuron projection guidanceGO:00974852410.014
developmental growthGO:00485892800.014
inorganic ion transmembrane transportGO:0098660730.014
ion transmembrane transportGO:00342201220.014
spermatogenesisGO:00072832000.013
kidney developmentGO:000182230.013
regulation of cellular protein metabolic processGO:00322682430.013
response to oxygen levelsGO:0070482590.013
Rat
positive regulation of nucleobase containing compound metabolic processGO:00459353320.013
positive regulation of nucleic acid templated transcriptionGO:19035082660.013
gland developmentGO:00487321910.013
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.013
lateral inhibitionGO:00463312060.013
response to organophosphorusGO:004668320.013
cellular response to organic substanceGO:00713101320.013
regulation of steroid metabolic processGO:001921820.013
cellular amine metabolic processGO:0044106120.013
response to endogenous stimulusGO:00097191190.013
protein transportGO:00150311550.013
response to hexoseGO:000974630.013
regulation of catabolic processGO:00098941700.013
very long chain fatty acid metabolic processGO:000003840.012
sulfur compound metabolic processGO:0006790590.012
regulation of cell deathGO:00109411730.012
acylglycerol catabolic processGO:004646430.012
response to alcoholGO:0097305950.012
positive regulation of rna metabolic processGO:00512542710.012
organonitrogen compound biosynthetic processGO:19015661170.012
regulation of transcription from rna polymerase ii promoterGO:00063573780.012
cellular protein localizationGO:00346131600.012
vitamin metabolic processGO:000676620.012
embryonic morphogenesisGO:00485982060.012
Fly
imaginal disc derived appendage developmentGO:00487373990.012
regulation of growthGO:00400082330.012
ribonucleotide metabolic processGO:00092591450.012
imaginal disc derived appendage morphogenesisGO:00351143950.012
negative regulation of macromolecule biosynthetic processGO:00105582700.012
nucleoside triphosphate metabolic processGO:00091411200.012
response to lipopolysaccharideGO:003249640.012
chemotaxisGO:00069352490.012
homeostatic processGO:00425921990.012
Rat
negative regulation of rna metabolic processGO:00512532510.012
negative regulation of nucleic acid templated transcriptionGO:19035072400.012
epidermis developmentGO:0008544650.012
brain developmentGO:00074201200.011
respiratory system developmentGO:00605412130.011
protein localizationGO:00081042840.011
ion homeostasisGO:0050801550.011
Rat
multicellular organismal agingGO:00102591400.011
localization of cellGO:00516742570.011
response to nutrient levelsGO:00316671140.011
androgen metabolic processGO:000820910.011
lipid localizationGO:0010876540.011
response to organic cyclic compoundGO:0014070890.011
enzyme linked receptor protein signaling pathwayGO:00071671790.011
digestive tract developmentGO:00485651490.011
Fly
ribonucleoside monophosphate metabolic processGO:0009161510.011
cell cell junction organizationGO:0045216550.011
positive regulation of cell motilityGO:200014730.011
cellular macromolecule localizationGO:00707272200.011
anion transportGO:0006820410.011
posttranscriptional regulation of gene expressionGO:00106081450.010
regulation of transportGO:00510491810.010
cellular amide metabolic processGO:0043603800.010
cellular response to endogenous stimulusGO:0071495800.010
biological adhesionGO:00226101380.010
regulation of proteolysisGO:0030162870.010
aromatic compound catabolic processGO:00194391660.010
connective tissue developmentGO:006144830.010
positive regulation of intracellular signal transductionGO:19025331160.010
negative regulation of transcription dna templatedGO:00458922370.010
rna processingGO:00063961470.010
positive regulation of cellular biosynthetic processGO:00313283160.010
hormone metabolic processGO:0042445330.010

Irp-1B disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.071
disease of anatomical entityDOID:700.035
inherited metabolic disorderDOID:65500.025
nervous system diseaseDOID:86300.022
carbohydrate metabolism diseaseDOID:005001300.019
acquired metabolic diseaseDOID:006015800.019
glucose metabolism diseaseDOID:419400.019
lipid metabolism disorderDOID:314600.014