IMP: Integrative Multi-species Prediction

Drosophila melanogaster

39 known processes

Nmt (Dmel_CG7436)

N-myristoyl transferase

(Aliases: nmt,153290_at,l(3)j1C7,dNMT,Nmt1,l(3)j1c7,Dmel\CG7436,CG7436)

Entrez: 38909
FLYBASE: FBgn0020392
UniProtKB: O61613

Process Predictions
Disease Predictions

Nmt biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
embryo development ending in birth or egg hatching	GO:0009792	152	0.988	Mouse Worm
embryonic morphogenesis	GO:0048598	206	0.903
gonad development	GO:0008406	50	0.594
spindle organization	GO:0007051	253	0.544
mitotic spindle organization	GO:0007052	220	0.515
response to external biotic stimulus	GO:0043207	293	0.506
protein modification process	GO:0036211	438	0.430
regulation of cell cycle	GO:0051726	291	0.424
cell migration	GO:0016477	238	0.408
mitotic g2 m transition checkpoint	GO:0044818	70	0.386
reproductive system development	GO:0061458	74	0.360
embryonic development via the syncytial blastoderm	GO:0001700	148	0.358
aging	GO:0007568	143	0.317
endocytosis	GO:0006897	310	0.303	Worm
taxis	GO:0042330	304	0.300
protein complex biogenesis	GO:0070271	201	0.280
establishment of localization in cell	GO:0051649	402	0.278
cellular protein modification process	GO:0006464	438	0.276
actin filament based process	GO:0030029	220	0.269
cellular catabolic process	GO:0044248	372	0.267
regulation of organelle organization	GO:0033043	196	0.257
regulation of protein metabolic process	GO:0051246	256	0.255
axonogenesis	GO:0007409	290	0.244
positive regulation of macromolecule metabolic process	GO:0010604	405	0.241
digestive system development	GO:0055123	149	0.237
small molecule metabolic process	GO:0044281	305	0.226
protein complex assembly	GO:0006461	200	0.225
rna splicing	GO:0008380	83	0.221
maintenance of location	GO:0051235	73	0.192
regulation of cellular localization	GO:0060341	136	0.191
regulation of cell cycle process	GO:0010564	181	0.190
regulation of meiosis	GO:0040020	3	0.189
localization of cell	GO:0051674	257	0.185
axon development	GO:0061564	297	0.177
death	GO:0016265	284	0.170	Worm
sex differentiation	GO:0007548	81	0.169
regulation of molecular function	GO:0065009	217	0.167
development of primary sexual characteristics	GO:0045137	50	0.162
vesicle mediated transport	GO:0016192	381	0.160	Worm
positive regulation of response to stimulus	GO:0048584	323	0.157
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.153
cell death	GO:0008219	279	0.152	Worm
axis specification	GO:0009798	167	0.139
response to biotic stimulus	GO:0009607	294	0.138
macromolecular complex assembly	GO:0065003	256	0.136
body morphogenesis	GO:0010171	2	0.134
organonitrogen compound metabolic process	GO:1901564	318	0.126
regulation of cellular component biogenesis	GO:0044087	201	0.124
actomyosin structure organization	GO:0031032	56	0.119
rna localization	GO:0006403	115	0.119
neuron projection guidance	GO:0097485	241	0.117
chemotaxis	GO:0006935	249	0.113
negative regulation of cellular protein metabolic process	GO:0032269	85	0.112
regulation of cellular ketone metabolic process	GO:0010565	3	0.110
morphogenesis of embryonic epithelium	GO:0016331	94	0.109
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.108
regionalization	GO:0003002	416	0.108
negative regulation of mitotic cell cycle	GO:0045930	109	0.104
tube morphogenesis	GO:0035239	191	0.104
regulation of cell division	GO:0051302	72	0.103
single organism biosynthetic process	GO:0044711	206	0.103
phosphorylation	GO:0016310	294	0.103
regulation of phosphate metabolic process	GO:0019220	210	0.100
mitotic nuclear division	GO:0007067	213	0.100
larval development	GO:0002164	104	0.099	Worm
regulation of proteolysis	GO:0030162	87	0.096
response to other organism	GO:0051707	293	0.095
antimicrobial humoral response	GO:0019730	99	0.095
mitotic dna integrity checkpoint	GO:0044774	75	0.093
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.093
positive regulation of nucleocytoplasmic transport	GO:0046824	24	0.092
mitotic dna damage checkpoint	GO:0044773	74	0.092
regulation of cellular protein metabolic process	GO:0032268	243	0.092
dna damage checkpoint	GO:0000077	78	0.091
cellular macromolecular complex assembly	GO:0034622	153	0.091
organic substance catabolic process	GO:1901575	308	0.091
regulation of rna splicing	GO:0043484	69	0.089
positive regulation of cell communication	GO:0010647	250	0.087
cell division	GO:0051301	248	0.085
gastrulation	GO:0007369	70	0.083
positive regulation of phosphate metabolic process	GO:0045937	139	0.081
multicellular organismal aging	GO:0010259	140	0.081
positive regulation of cellular protein metabolic process	GO:0032270	118	0.080
dna integrity checkpoint	GO:0031570	81	0.079
male gamete generation	GO:0048232	201	0.077
organic cyclic compound catabolic process	GO:1901361	168	0.076
single organism catabolic process	GO:0044712	228	0.072
regulation of mrna splicing via spliceosome	GO:0048024	64	0.071
determination of adult lifespan	GO:0008340	137	0.071
single organism cellular localization	GO:1902580	180	0.071
dendrite morphogenesis	GO:0048813	199	0.070
actin cytoskeleton organization	GO:0030036	206	0.070
reproductive behavior	GO:0019098	122	0.067
mitotic g2 dna damage checkpoint	GO:0007095	69	0.066
intracellular mrna localization	GO:0008298	66	0.065
oxoacid metabolic process	GO:0043436	103	0.063
nuclear division	GO:0000280	332	0.063
regulation of localization	GO:0032879	275	0.063
negative regulation of molecular function	GO:0044092	51	0.063
positive regulation of cellular component biogenesis	GO:0044089	80	0.062
pole plasm oskar mrna localization	GO:0045451	46	0.062
positive regulation of signal transduction	GO:0009967	223	0.060
proteolysis	GO:0006508	192	0.059
digestive tract morphogenesis	GO:0048546	127	0.058
g2 dna damage checkpoint	GO:0031572	69	0.057
spindle assembly involved in mitosis	GO:0090307	50	0.057
lipid localization	GO:0010876	54	0.055
mrna metabolic process	GO:0016071	124	0.055
embryonic axis specification	GO:0000578	107	0.055
organelle localization	GO:0051640	148	0.054
regulation of cysteine type endopeptidase activity involved in apoptotic process	GO:0043281	25	0.053
aromatic compound catabolic process	GO:0019439	166	0.053
cellular response to dna damage stimulus	GO:0006974	223	0.053
cell motility	GO:0048870	251	0.052
reproductive structure development	GO:0048608	74	0.052
programmed cell death	GO:0012501	257	0.051	Worm
pole plasm rna localization	GO:0007316	52	0.051
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.049
cytokinesis	GO:0000910	90	0.048
blastoderm segmentation	GO:0007350	159	0.048
mrna splicing via spliceosome	GO:0000398	73	0.047
positive regulation of rna metabolic process	GO:0051254	271	0.047
developmental maturation	GO:0021700	172	0.047
dendrite development	GO:0016358	204	0.047
dorsal closure	GO:0007391	79	0.046
response to radiation	GO:0009314	155	0.046
regulation of protein complex assembly	GO:0043254	42	0.045
positive regulation of transport	GO:0051050	92	0.045
positive regulation of cellular biosynthetic process	GO:0031328	316	0.045
dna metabolic process	GO:0006259	227	0.044
protein processing	GO:0016485	68	0.044
regulation of alternative mrna splicing via spliceosome	GO:0000381	60	0.044
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.043
negative regulation of cellular metabolic process	GO:0031324	382	0.043
regulation of phosphorus metabolic process	GO:0051174	210	0.043
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.043
axon guidance	GO:0007411	233	0.042
pigment metabolic process	GO:0042440	84	0.042
positive regulation of catalytic activity	GO:0043085	118	0.042
macromolecule catabolic process	GO:0009057	161	0.041
regulation of catalytic activity	GO:0050790	185	0.040
receptor mediated endocytosis	GO:0006898	21	0.040	Worm
negative regulation of cell cycle	GO:0045786	116	0.040
exocrine system development	GO:0035272	162	0.040
regulation of endopeptidase activity	GO:0052548	36	0.038
anterior posterior axis specification embryo	GO:0008595	103	0.038
digestive tract development	GO:0048565	149	0.037
positive regulation of signaling	GO:0023056	243	0.037
regulation of mitotic cell cycle	GO:0007346	190	0.036
regulation of mrna metabolic process	GO:1903311	72	0.036
central nervous system development	GO:0007417	201	0.035
regulation of catabolic process	GO:0009894	170	0.035
imaginal disc derived wing morphogenesis	GO:0007476	337	0.035
positive regulation of rna biosynthetic process	GO:1902680	266	0.035
phagocytosis	GO:0006909	215	0.035
molting cycle	GO:0042303	56	0.034
cellular macromolecule catabolic process	GO:0044265	136	0.034
meiotic cell cycle	GO:0051321	171	0.034
mitotic cell cycle phase transition	GO:0044772	138	0.033
organelle assembly	GO:0070925	198	0.033
protein transport	GO:0015031	155	0.033
regulation of peptidase activity	GO:0052547	39	0.033
chromosome organization	GO:0051276	360	0.033
ribonucleoprotein complex assembly	GO:0022618	23	0.033
multicellular organismal reproductive behavior	GO:0033057	110	0.033
developmental growth	GO:0048589	280	0.033
growth	GO:0040007	359	0.033
embryonic pattern specification	GO:0009880	174	0.032
cellular nitrogen compound catabolic process	GO:0044270	165	0.031
positive regulation of cell migration	GO:0030335	2	0.031
regulation of synapse structure and activity	GO:0050803	128	0.030
regulation of intracellular transport	GO:0032386	64	0.030
defense response to other organism	GO:0098542	225	0.030
snrna metabolic process	GO:0016073	14	0.030
purine nucleoside catabolic process	GO:0006152	112	0.029
nucleobase containing compound catabolic process	GO:0034655	165	0.029
immune system process	GO:0002376	347	0.028
epidermis development	GO:0008544	65	0.028
intracellular transport	GO:0046907	228	0.028
positive regulation of nfat protein import into nucleus	GO:0051533	16	0.028
intracellular protein transport	GO:0006886	104	0.027
regulation of transport	GO:0051049	181	0.027
regulation of cytoskeleton organization	GO:0051493	89	0.027
positive regulation of multicellular organismal process	GO:0051240	143	0.027
cognition	GO:0050890	141	0.026
negative regulation of catalytic activity	GO:0043086	42	0.026
regulation of mrna processing	GO:0050684	71	0.026
organic acid metabolic process	GO:0006082	103	0.026
regulation of multicellular organismal development	GO:2000026	414	0.025
positive regulation of molecular function	GO:0044093	136	0.025
cell cycle checkpoint	GO:0000075	95	0.025
heterocycle catabolic process	GO:0046700	166	0.025
microtubule cytoskeleton organization involved in mitosis	GO:1902850	52	0.025
regulation of humoral immune response	GO:0002920	51	0.025
positive regulation of gene expression	GO:0010628	290	0.025
establishment of organelle localization	GO:0051656	122	0.025
rna processing	GO:0006396	147	0.024
oocyte axis specification	GO:0007309	108	0.024
epidermal cell differentiation	GO:0009913	51	0.024
positive regulation of cell motility	GO:2000147	3	0.024
immune effector process	GO:0002252	98	0.024
regulation of establishment of protein localization	GO:0070201	61	0.024
rna splicing via transesterification reactions	GO:0000375	73	0.023
organonitrogen compound biosynthetic process	GO:1901566	117	0.023
oxidation reduction process	GO:0055114	123	0.023
defense response to bacterium	GO:0042742	178	0.023
negative regulation of protein metabolic process	GO:0051248	85	0.023
alternative mrna splicing via spliceosome	GO:0000380	60	0.023
compound eye morphogenesis	GO:0001745	249	0.022
tube development	GO:0035295	244	0.022
multi organism reproductive behavior	GO:0044705	121	0.022
positive regulation of proteolysis	GO:0045862	52	0.022
organic substance transport	GO:0071702	257	0.021
catabolic process	GO:0009056	409	0.021
genitalia development	GO:0048806	26	0.021
oviposition	GO:0018991	19	0.021
mrna processing	GO:0006397	104	0.021
protein targeting to nucleus	GO:0044744	51	0.020
connective tissue development	GO:0061448	3	0.020
regulation of protein modification process	GO:0031399	112	0.020
positive regulation of cellular component organization	GO:0051130	156	0.020
muscle structure development	GO:0061061	224	0.020
modification dependent macromolecule catabolic process	GO:0043632	79	0.019
negative regulation of developmental process	GO:0051093	201	0.019
cellular ketone metabolic process	GO:0042180	24	0.019
regulation of cellular catabolic process	GO:0031329	157	0.019
cellular macromolecule localization	GO:0070727	220	0.019
single fertilization	GO:0007338	24	0.019
cell cycle phase transition	GO:0044770	140	0.019
mapk cascade	GO:0000165	107	0.019
regulation of response to stress	GO:0080134	200	0.019
positive regulation of protein metabolic process	GO:0051247	128	0.019
single organismal cell cell adhesion	GO:0016337	45	0.019
purine containing compound metabolic process	GO:0072521	155	0.019
defense response	GO:0006952	300	0.019
regulation of microtubule cytoskeleton organization	GO:0070507	41	0.018
glycosyl compound catabolic process	GO:1901658	112	0.018
salivary gland development	GO:0007431	162	0.018
regulation of immune response	GO:0050776	118	0.018
regulation of protein phosphorylation	GO:0001932	64	0.018
developmental programmed cell death	GO:0010623	138	0.018
spermatogenesis	GO:0007283	200	0.018
single organism cell adhesion	GO:0098602	47	0.018
gene silencing by rna	GO:0031047	57	0.017
amine metabolic process	GO:0009308	12	0.017
oocyte anterior posterior axis specification	GO:0007314	72	0.017
regulation of cytoplasmic transport	GO:1903649	47	0.017
carbohydrate derivative metabolic process	GO:1901135	217	0.017
kidney development	GO:0001822	3	0.017
positive regulation of biosynthetic process	GO:0009891	316	0.017
striated muscle myosin thick filament assembly	GO:0071688	3	0.017
protein dna complex subunit organization	GO:0071824	86	0.017
negative regulation of cell cycle phase transition	GO:1901988	103	0.017
immune response	GO:0006955	246	0.017
meiotic nuclear division	GO:0007126	151	0.016
synaptic growth at neuromuscular junction	GO:0051124	119	0.016
multi organism behavior	GO:0051705	175	0.016
purine containing compound catabolic process	GO:0072523	112	0.016
humoral immune response	GO:0006959	117	0.016
regulation of nuclear division	GO:0051783	58	0.016
mesoderm development	GO:0007498	78	0.016
positive regulation of immune response	GO:0050778	63	0.016
appendage morphogenesis	GO:0035107	397	0.016
cellular protein complex assembly	GO:0043623	71	0.015
cytoplasm organization	GO:0007028	64	0.015
negative regulation of cell cycle process	GO:0010948	109	0.015
regulation of wnt signaling pathway	GO:0030111	68	0.015
pole plasm assembly	GO:0007315	61	0.015
regulation of hydrolase activity	GO:0051336	97	0.015
morphogenesis of an epithelium	GO:0002009	276	0.015
regulation of locomotion	GO:0040012	42	0.015
regulation of notch signaling pathway	GO:0008593	100	0.015
anterior posterior axis specification	GO:0009948	109	0.015
positive regulation of mrna processing	GO:0050685	4	0.015
multi multicellular organism process	GO:0044706	123	0.015
dephosphorylation	GO:0016311	51	0.014
apoptotic process	GO:0006915	159	0.014	Worm
regulation of cellular amino acid metabolic process	GO:0006521	0	0.014
myofibril assembly	GO:0030239	36	0.014
positive regulation of phosphorus metabolic process	GO:0010562	139	0.014
positive regulation of transcription factor import into nucleus	GO:0042993	19	0.014
epithelium migration	GO:0090132	148	0.014
segmentation	GO:0035282	207	0.014
cytoplasmic transport	GO:0016482	130	0.014
negative regulation of endopeptidase activity	GO:0010951	11	0.014
posttranscriptional regulation of gene expression	GO:0010608	145	0.014
regulation of multi organism process	GO:0043900	131	0.014
purine ribonucleoside metabolic process	GO:0046128	127	0.014
proteasomal protein catabolic process	GO:0010498	59	0.014
activation of cysteine type endopeptidase activity involved in apoptotic process	GO:0006919	16	0.014
camera type eye development	GO:0043010	4	0.014
dna repair	GO:0006281	54	0.014
response to dsrna	GO:0043331	15	0.014
cellular response to chemical stimulus	GO:0070887	199	0.013
glycosyl compound metabolic process	GO:1901657	127	0.013
negative regulation of phosphate metabolic process	GO:0045936	45	0.013
wnt signaling pathway	GO:0016055	98	0.013
regulation of response to external stimulus	GO:0032101	115	0.013
pole plasm mrna localization	GO:0019094	49	0.012
response to abiotic stimulus	GO:0009628	341	0.012
transmembrane transport	GO:0055085	139	0.012
single organism intracellular transport	GO:1902582	207	0.012
carbohydrate derivative biosynthetic process	GO:1901137	85	0.012
protein catabolic process	GO:0030163	101	0.012
notch signaling pathway	GO:0007219	120	0.012
rna splicing via transesterification reactions with bulged adenosine as nucleophile	GO:0000377	73	0.012
transcription from rna polymerase ii promoter	GO:0006366	368	0.012
regulation of cellular amine metabolic process	GO:0033238	3	0.012
regulation of synapse organization	GO:0050807	110	0.012
ameboidal type cell migration	GO:0001667	151	0.012
nucleotide catabolic process	GO:0009166	109	0.012
spindle localization	GO:0051653	22	0.012
regulation of apoptotic process	GO:0042981	130	0.011
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.011
cellular response to nutrient	GO:0031670	1	0.011
ribonucleoside catabolic process	GO:0042454	112	0.011
mitotic cell cycle checkpoint	GO:0007093	88	0.011
regulation of immune system process	GO:0002682	176	0.011
homeostatic process	GO:0042592	199	0.011
cell proliferation	GO:0008283	299	0.011
establishment of mitotic spindle localization	GO:0040001	17	0.011
epithelial cell differentiation	GO:0030855	322	0.011
response to virus	GO:0009615	28	0.011
positive regulation of endopeptidase activity	GO:0010950	26	0.011
protein phosphorylation	GO:0006468	169	0.011
positive regulation of cellular amine metabolic process	GO:0033240	0	0.011
nucleoside catabolic process	GO:0009164	112	0.011
carboxylic acid metabolic process	GO:0019752	92	0.010
response to bacterium	GO:0009617	198	0.010
cell maturation	GO:0048469	144	0.010
establishment of protein localization	GO:0045184	163	0.010
tissue morphogenesis	GO:0048729	297	0.010
organelle fission	GO:0048285	340	0.010
regulation of phosphorylation	GO:0042325	147	0.010
cellular protein complex disassembly	GO:0043624	35	0.010
histone modification	GO:0016570	106	0.010
cytoskeleton dependent cytokinesis	GO:0061640	81	0.010
protein maturation	GO:0051604	71	0.010

Nmt disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	musculoskeletal system disease	DOID:17	0	0.014
	disease of anatomical entity	DOID:7	0	0.014

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