Drosophila melanogaster

126 known processes

bif (Dmel_CG1822)

bifocal

(Aliases: Dmel\CG1822,CG1822)

bif biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
axon guidanceGO:00074112330.961
eye developmentGO:00016543230.958
sensory organ morphogenesisGO:00905962600.950
compound eye developmentGO:00487493070.906
neuron projection guidanceGO:00974852410.859
chemotaxisGO:00069352490.831
compound eye morphogenesisGO:00017452490.822
regulation of protein polymerizationGO:0032271280.822
female meiosis chromosome segregationGO:0016321330.820
cell proliferationGO:00082832990.792
axonogenesisGO:00074092900.779
r7 cell differentiationGO:0045466430.769
regulation of actin filament polymerizationGO:0030833250.711
developmental programmed cell deathGO:00106231380.684
actin filament organizationGO:00070151260.680
regulation of actin polymerization or depolymerizationGO:0008064270.678
photoreceptor cell differentiationGO:00465301700.664
actin polymerization or depolymerizationGO:0008154310.639
deathGO:00162652840.636
actin filament polymerizationGO:0030041270.611
organelle localizationGO:00516401480.608
tissue deathGO:00162711020.595
regulation of cell projection assemblyGO:0060491300.555
eye morphogenesisGO:00485922600.551
axon developmentGO:00615642970.510
regulation of cell proliferationGO:00421271630.509
establishment or maintenance of cell polarityGO:00071631670.486
synaptic growth at neuromuscular junctionGO:00511241190.484
compound eye photoreceptor cell differentiationGO:00017511400.472
regulation of protein metabolic processGO:00512462560.471
nucleus localizationGO:0051647340.470
regulation of actin cytoskeleton organizationGO:0032956420.457
phosphorylationGO:00163102940.448
salivary gland morphogenesisGO:00074351450.436
programmed cell deathGO:00125012570.431
lipid metabolic processGO:00066291210.416
regulation of catabolic processGO:00098941700.406
compound eye photoreceptor developmentGO:0042051780.396
protein phosphorylationGO:00064681690.394
protein modification processGO:00362114380.388
actin cytoskeleton organizationGO:00300362060.386
regulation of cellular catabolic processGO:00313291570.384
protein complex biogenesisGO:00702712010.365
regulation of cytoskeleton organizationGO:0051493890.358
cellular protein modification processGO:00064644380.358
regulation of actin filament lengthGO:0030832270.355
exocrine system developmentGO:00352721620.346
regulation of cell shapeGO:00083601130.315
meiotic cell cycleGO:00513211710.307
negative regulation of phosphorus metabolic processGO:0010563450.301
cell adhesionGO:00071551360.293
protein polymerizationGO:0051258420.286
epithelial cell developmentGO:00020642740.285
positive regulation of cytoskeleton organizationGO:0051495210.282
cell deathGO:00082192790.279
epithelial cell differentiationGO:00308553220.263
nuclear migrationGO:0007097200.261
reproductive structure developmentGO:0048608740.250
female meiotic divisionGO:0007143700.246
developmental growthGO:00485892800.243
glycosyl compound catabolic processGO:19016581120.239
establishment of nucleus localizationGO:0040023260.238
meiotic cell cycle processGO:19030461320.235
actin filament based processGO:00300292200.234
cell migrationGO:00164772380.229
regulation of cellular component sizeGO:0032535980.227
actin filament bundle organizationGO:0061572280.225
endocytosisGO:00068973100.220
regulation of cellular component biogenesisGO:00440872010.212
spindle organizationGO:00070512530.211
gland developmentGO:00487321910.208
skin developmentGO:0043588650.202
positive regulation of catabolic processGO:00098961050.202
regionalizationGO:00030024160.200
eye photoreceptor cell developmentGO:0042462810.197
apoptotic processGO:00069151590.197
regulation of embryonic developmentGO:0045995680.196
regulation of organelle organizationGO:00330431960.193
growthGO:00400073590.192
regulation of response to stressGO:00801342000.187
central nervous system developmentGO:00074172010.178
organelle assemblyGO:00709251980.178
cellular protein complex assemblyGO:0043623710.177
regulation of programmed cell deathGO:00430671520.176
ras protein signal transductionGO:0007265880.176
epithelium migrationGO:00901321480.171
positive regulation of cellular component biogenesisGO:0044089800.171
eye photoreceptor cell differentiationGO:00017541450.170
tube developmentGO:00352952440.170
histolysisGO:00075591020.166
transcription from rna polymerase ii promoterGO:00063663680.166
positive regulation of nitrogen compound metabolic processGO:00511733540.165
negative regulation of cellular component organizationGO:00511291080.164
macromolecular complex assemblyGO:00650032560.162
vesicle mediated transportGO:00161923810.159
positive regulation of cell deathGO:0010942690.157
actin cytoskeleton reorganizationGO:0031532220.156
negative regulation of phosphate metabolic processGO:0045936450.144
establishment of spindle localizationGO:0051293220.143
regulation of protein complex assemblyGO:0043254420.136
cellular catabolic processGO:00442483720.133
establishment of cell polarityGO:0030010400.129
negative regulation of signalingGO:00230572190.126
immune system processGO:00023763470.126
positive regulation of protein complex assemblyGO:0031334220.125
positive regulation of autophagyGO:0010508210.124
lipid modificationGO:0030258240.121
tube morphogenesisGO:00352391910.121
ovarian follicle cell developmentGO:00307072480.120
regulation of actin filament based processGO:0032970420.118
positive regulation of response to external stimulusGO:0032103440.117
purine containing compound catabolic processGO:00725231120.117
protein complex assemblyGO:00064612000.114
negative regulation of erbb signaling pathwayGO:1901185290.112
sensory perceptionGO:00076001960.112
regulation of response to external stimulusGO:00321011150.111
meiotic chromosome segregationGO:0045132590.111
taxisGO:00423303040.111
negative regulation of cell proliferationGO:0008285690.111
regulation of protein modification processGO:00313991120.110
salivary gland histolysisGO:0035070880.109
intracellular signal transductionGO:00355563000.108
development of primary sexual characteristicsGO:0045137500.106
negative regulation of organelle organizationGO:0010639560.104
regulation of apoptotic processGO:00429811300.101
regulation of cell deathGO:00109411730.101
regulation of cell morphogenesisGO:00226041630.098
organelle fissionGO:00482853400.098
regulation of cell growthGO:0001558430.096
salivary gland developmentGO:00074311620.093
reproductive behaviorGO:00190981220.093
single organism catabolic processGO:00447122280.091
negative regulation of cell cycleGO:00457861160.091
autophagic cell deathGO:0048102830.091
ameboidal type cell migrationGO:00016671510.091
regulation of cell differentiationGO:00455953020.089
positive regulation of gtp catabolic processGO:0033126430.088
small gtpase mediated signal transductionGO:0007264880.085
positive regulation of cell communicationGO:00106472500.084
positive regulation of protein polymerizationGO:0032273140.084
catabolic processGO:00090564090.083
rho protein signal transductionGO:0007266140.082
cell motilityGO:00488702510.081
organophosphate metabolic processGO:00196371950.081
cellular lipid metabolic processGO:0044255830.079
cellular component assembly involved in morphogenesisGO:00109271510.077
purine nucleoside triphosphate metabolic processGO:00091441190.077
positive regulation of macromolecule metabolic processGO:00106044050.076
extracellular structure organizationGO:0043062460.075
unidimensional cell growthGO:0009826150.075
imaginal disc derived leg morphogenesisGO:0007480800.074
negative regulation of phosphorylationGO:0042326350.073
regulation of phosphate metabolic processGO:00192202100.073
purine ribonucleoside triphosphate metabolic processGO:00092051190.072
regulation of erbb signaling pathwayGO:1901184420.071
negative regulation of multicellular organismal processGO:00512411420.071
lamellipodium organizationGO:0097581210.071
photoreceptor cell developmentGO:0042461960.070
establishment of localization in cellGO:00516494020.070
positive regulation of signalingGO:00230562430.069
regulation of phosphorylationGO:00423251470.069
establishment of spindle orientationGO:0051294180.067
maintenance of protein locationGO:0045185280.067
positive regulation of proteolysisGO:0045862520.067
regulation of intracellular signal transductionGO:19025312360.066
positive regulation of protein metabolic processGO:00512471280.065
regulation of immune responseGO:00507761180.064
protein localizationGO:00081042840.062
organonitrogen compound metabolic processGO:19015643180.061
establishment of organelle localizationGO:00516561220.060
positive regulation of protein phosphorylationGO:0001934340.060
adult somatic muscle developmentGO:0007527140.060
post embryonic appendage morphogenesisGO:00351203850.059
positive regulation of cellular protein metabolic processGO:00322701180.059
syncytium formationGO:0006949430.059
regulation of small gtpase mediated signal transductionGO:0051056930.059
positive regulation of hydrolase activityGO:0051345780.057
body morphogenesisGO:001017120.057
ovarian follicle cell migrationGO:00072971210.056
mapk cascadeGO:00001651070.056
leg disc developmentGO:0035218920.055
macroautophagyGO:0016236420.055
reproductive system developmentGO:0061458740.055
single organism cell adhesionGO:0098602470.052
single organism intracellular transportGO:19025822070.052
regulation of neuron deathGO:1901214260.052
regulation of anatomical structure morphogenesisGO:00226032420.052
regulation of anatomical structure sizeGO:00900661630.052
chaeta developmentGO:0022416970.051
regulation of stress activated protein kinase signaling cascadeGO:0070302420.051
oocyte constructionGO:00073081120.051
positive regulation of cellular catabolic processGO:0031331950.050
aromatic compound catabolic processGO:00194391660.050
regulation of synapse structure and activityGO:00508031280.049
cellular macromolecular complex assemblyGO:00346221530.049
digestive tract morphogenesisGO:00485461270.049
regulation of nervous system developmentGO:00519602480.049
positive regulation of organelle organizationGO:0010638650.048
carbohydrate derivative catabolic processGO:19011361180.048
sex differentiationGO:0007548810.047
organic substance catabolic processGO:19015753080.047
dephosphorylationGO:0016311510.047
tissue migrationGO:00901301550.047
oocyte developmentGO:00485991240.047
jnk cascadeGO:0007254500.046
embryonic morphogenesisGO:00485982060.046
antimicrobial humoral responseGO:0019730990.045
regulation of organ morphogenesisGO:2000027780.042
regulation of cell developmentGO:00602842150.042
cortical cytoskeleton organizationGO:0030865290.042
chromosome segregationGO:00070591570.041
cell projection assemblyGO:0030031940.041
epidermal cell differentiationGO:0009913510.041
spindle localizationGO:0051653220.040
rna processingGO:00063961470.040
regulation of localizationGO:00328792750.039
appendage morphogenesisGO:00351073970.039
respiratory system developmentGO:00605412130.039
regulation of protein phosphorylationGO:0001932640.039
purine nucleotide metabolic processGO:00061631460.039
gastrulationGO:0007369700.038
heterocycle catabolic processGO:00467001660.038
cellular response to chemical stimulusGO:00708871990.038
male gamete generationGO:00482322010.038
regulation of canonical wnt signaling pathwayGO:0060828150.038
positive regulation of apoptotic processGO:0043065470.038
tissue morphogenesisGO:00487292970.037
positive regulation of signal transductionGO:00099672230.037
regulation of growthGO:00400082330.037
epidermis developmentGO:0008544650.036
regulation of protein modification by small protein conjugation or removalGO:1903320250.036
regulation of catalytic activityGO:00507901850.036
regulation of cellular protein metabolic processGO:00322682430.036
nuclear divisionGO:00002803320.036
cellular amine metabolic processGO:0044106120.035
response to other organismGO:00517072930.035
guanosine containing compound metabolic processGO:1901068740.034
purine ribonucleotide metabolic processGO:00091501450.034
purine nucleotide catabolic processGO:00061951090.034
retinal cell programmed cell deathGO:0046666250.033
protein modification by small protein conjugation or removalGO:00706471060.033
digestive tract developmentGO:00485651490.033
protein ubiquitinationGO:0016567700.032
neuromuscular junction developmentGO:00075281490.032
negative regulation of protein phosphorylationGO:0001933170.032
proteolysisGO:00065081920.032
salivary gland cell autophagic cell deathGO:0035071830.031
ribonucleotide catabolic processGO:00092611090.031
response to biotic stimulusGO:00096072940.031
asymmetric cell divisionGO:0008356370.031
regulation of molecular functionGO:00650092170.031
positive regulation of programmed cell deathGO:0043068620.030
localization of cellGO:00516742570.030
regulation of embryonic cell shapeGO:0016476300.030
negative regulation of cellular metabolic processGO:00313243820.030
startle responseGO:0001964160.030
morphogenesis of an epitheliumGO:00020092760.029
single organismal cell cell adhesionGO:0016337450.029
regulation of multicellular organismal developmentGO:20000264140.029
positive regulation of jun kinase activityGO:004350740.029
phagocytosisGO:00069092150.029
synapse assemblyGO:00074161430.028
epithelial cell morphogenesisGO:0003382250.028
rna 3 end processingGO:0031123450.028
nucleobase containing compound catabolic processGO:00346551650.028
regulation of phosphorus metabolic processGO:00511742100.028
embryo development ending in birth or egg hatchingGO:00097921520.028
axon extensionGO:0048675320.028
positive regulation of nucleobase containing compound metabolic processGO:00459353320.027
negative regulation of transcription dna templatedGO:00458922370.027
synapse organizationGO:00508081960.027
stem cell divisionGO:0017145690.027
negative regulation of cell communicationGO:00106482230.027
regulation of immune system processGO:00026821760.026
regulation of cellular amino acid metabolic processGO:000652100.026
negative regulation of response to stimulusGO:00485852580.026
biological adhesionGO:00226101380.026
negative regulation of developmental growthGO:0048640640.026
regulation of protein ubiquitinationGO:0031396220.026
brain developmentGO:00074201200.026
cell recognitionGO:00080371020.026
signal transduction by phosphorylationGO:00230141070.026
negative regulation of protein modification processGO:0031400290.026
imaginal disc derived appendage morphogenesisGO:00351143950.025
organ growthGO:0035265560.025
positive regulation of molecular functionGO:00440931360.025
positive regulation of ras gtpase activityGO:0032320360.025
regulation of protein localizationGO:0032880760.025
positive regulation of transcription dna templatedGO:00458932660.025
microtubule based movementGO:0007018510.024
purine ribonucleoside triphosphate catabolic processGO:00092071080.024
embryonic development via the syncytial blastodermGO:00017001480.024
regulation of jnk cascadeGO:0046328400.024
positive regulation of cellular component organizationGO:00511301560.024
arp2 3 complex mediated actin nucleationGO:003431430.024
oocyte anterior posterior axis specificationGO:0007314720.024
sensory perception of mechanical stimulusGO:0050954720.023
axis specificationGO:00097981670.023
border follicle cell migrationGO:00072981130.023
positive regulation of phosphorus metabolic processGO:00105621390.023
regulation of autophagyGO:0010506620.023
regulation of endocytosisGO:0030100370.023
negative regulation of transferase activityGO:0051348180.023
synaptic transmissionGO:00072682880.023
regulation of response to nutrient levelsGO:0032107180.023
organonitrogen compound catabolic processGO:19015651280.023
negative regulation of signal transductionGO:00099682060.023
cytoplasmic transportGO:00164821300.022
appendage developmentGO:00487364010.022
regulation of immune effector processGO:0002697520.022
chromosome organizationGO:00512763600.022
purine nucleoside triphosphate catabolic processGO:00091461080.022
hair cell differentiationGO:0035315470.022
actin nucleationGO:004501080.022
meiosis iGO:0007127590.022
cell growthGO:00160491080.022
protein modification by small protein conjugationGO:0032446790.022
regulation of transportGO:00510491810.022
larval developmentGO:00021641040.021
establishment or maintenance of cytoskeleton polarityGO:0030952440.021
neuron recognitionGO:00080381010.021
regulation of defense responseGO:00313471020.021
positive regulation of catalytic activityGO:00430851180.021
defense responseGO:00069523000.021
ribonucleoside metabolic processGO:00091191270.021
negative regulation of neurogenesisGO:0050768530.021
purine ribonucleoside metabolic processGO:00461281270.021
purine containing compound metabolic processGO:00725211550.021
positive regulation of apoptotic signaling pathwayGO:200123540.020
establishment or maintenance of apical basal cell polarityGO:0035088340.020
cortical actin cytoskeleton organizationGO:0030866240.020
convergent extension involved in gastrulationGO:006002720.020
negative regulation of synapse assemblyGO:0051964390.019
germarium derived egg chamber formationGO:00072931010.019
purine nucleoside catabolic processGO:00061521120.019
positive regulation of response to stimulusGO:00485843230.019
establishment or maintenance of microtubule cytoskeleton polarityGO:0030951410.019
positive regulation of protein modification processGO:0031401580.019
positive regulation of phosphorylationGO:0042327870.019
regulation of transferase activityGO:0051338580.019
dendrite morphogenesisGO:00488131990.018
segmentationGO:00352822070.018
regulation of mapk cascadeGO:0043408920.018
actin filament bundle assemblyGO:0051017260.018
meiotic spindle organizationGO:0000212360.018
regulation of chromosome organizationGO:0033044640.018
immune responseGO:00069552460.018
cytoplasmic microtubule organizationGO:0031122220.018
nucleoside triphosphate catabolic processGO:00091431080.017
intracellular transportGO:00469072280.017
gtp metabolic processGO:0046039720.017
nucleoside phosphate catabolic processGO:19012921100.017
negative regulation of growthGO:0045926840.017
positive regulation of actin filament polymerizationGO:0030838110.016
positive regulation of intracellular signal transductionGO:19025331160.016
imaginal disc derived wing morphogenesisGO:00074763370.016
macromolecule catabolic processGO:00090571610.016
positive regulation of nucleoside metabolic processGO:0045979470.016
endomembrane system organizationGO:00102561190.016
negative regulation of neuron deathGO:1901215180.016
optic placode formationGO:000174340.016
positive regulation of cell projection organizationGO:0031346290.016
ribose phosphate metabolic processGO:00196931450.016
regulation of hydrolase activityGO:0051336970.015
regulation of cell projection organizationGO:0031344920.015
oocyte axis specificationGO:00073091080.015
cardiovascular system developmentGO:0072358820.015
nephron epithelium developmentGO:007200930.015
glutamate secretionGO:001404710.015
meiotic nuclear divisionGO:00071261510.015
regulation of cellular amine metabolic processGO:003323830.015
sphingolipid metabolic processGO:0006665190.015
regulation of cytokinesisGO:003246530.015
positive regulation of wnt signaling pathwayGO:0030177250.015
regulation of cell sizeGO:0008361630.015
negative regulation of protein depolymerizationGO:1901880230.015
positive regulation of purine nucleotide metabolic processGO:1900544550.015
negative regulation of developmental processGO:00510932010.015
spermatid differentiationGO:00485151140.015
regulation of cell cycleGO:00517262910.015
positive regulation of protein tyrosine kinase activityGO:006109840.015
circulatory system developmentGO:0072359820.014
dendrite developmentGO:00163582040.014
photoreceptor cell morphogenesisGO:0008594180.014
negative regulation of biosynthetic processGO:00098902770.014
regulation of stress activated mapk cascadeGO:0032872410.014
gonad developmentGO:0008406500.014
syncytium formation by plasma membrane fusionGO:0000768430.014
phospholipid metabolic processGO:0006644230.014
spindle elongationGO:0051231830.014
negative regulation of protein metabolic processGO:0051248850.014
regulation of gtpase activityGO:0043087440.014
covalent chromatin modificationGO:00165691060.014
positive regulation of actin nucleationGO:005112710.013
regulation of hemocyte proliferationGO:0035206370.013
regulation of developmental pigmentationGO:0048070240.013
imaginal disc derived appendage developmentGO:00487373990.013
negative regulation of cell developmentGO:0010721620.013
regulation of nucleoside metabolic processGO:0009118500.013
histone modificationGO:00165701060.013
peptidyl amino acid modificationGO:00181931050.013
nucleus organizationGO:0006997450.013
regulation of protein localization to nucleusGO:1900180290.013
axis elongationGO:000340130.013
gland morphogenesisGO:00226121450.013
anterior posterior axis specification embryoGO:00085951030.012
oocyte differentiationGO:00099941450.012
axon extension involved in axon guidanceGO:0048846100.012
regulation of neurogenesisGO:00507671580.012
cilium organizationGO:0044782410.012
regulation of oocyte developmentGO:0060281270.012
nucleoside phosphate metabolic processGO:00067531620.012
establishment of tissue polarityGO:0007164870.012
morphogenesis of a polarized epitheliumGO:0001738930.012
antimicrobial peptide productionGO:0002775460.012
receptor mediated endocytosisGO:0006898210.012
neuron apoptotic processGO:0051402170.012
cellular protein localizationGO:00346131600.012
organic substance transportGO:00717022570.012
positive regulation of multicellular organismal processGO:00512401430.012
cellular macromolecule localizationGO:00707272200.012
ribonucleoside triphosphate metabolic processGO:00091991190.012
membrane lipid metabolic processGO:0006643220.012
regulation of cell cell adhesionGO:0022407210.011
amine metabolic processGO:0009308120.011
positive regulation of cellular amino acid metabolic processGO:004576400.011
regulation of behaviorGO:0050795750.011
nucleotide metabolic processGO:00091171610.011
retinal ganglion cell axon guidanceGO:0031290120.011
regulation of phosphatase activityGO:001092130.011
negative regulation of kinase activityGO:0033673160.011
regulation of synapse assemblyGO:0051963940.011
regulation of proteolysisGO:0030162870.011
lateral inhibitionGO:00463312060.011
glycosyl compound metabolic processGO:19016571270.011
positive regulation of transferase activityGO:0051347260.011
regulation of ras protein signal transductionGO:0046578930.011
cell junction organizationGO:0034330570.011
positive regulation of phosphate metabolic processGO:00459371390.011
response to nutrient levelsGO:00316671140.011
muscle cell differentiationGO:00426921030.011
negative regulation of cyclin dependent protein serine threonine kinase activityGO:004573610.011
establishment of planar polarityGO:0001736870.010
muscle cell migrationGO:001481230.010
regulation of kinase activityGO:0043549530.010
epidermal growth factor receptor signaling pathwayGO:0007173580.010
response to radiationGO:00093141550.010
regulation of synaptic growth at neuromuscular junctionGO:0008582890.010
digestive system developmentGO:00551231490.010
maintenance of locationGO:0051235730.010
regulation of cellular component movementGO:0051270420.010
regulation of purine nucleotide metabolic processGO:1900542620.010
stress activated mapk cascadeGO:0051403520.010
motor neuron axon guidanceGO:0008045580.010
positive regulation of kinase activityGO:0033674250.010

bif disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.038
cancerDOID:16200.038
organ system cancerDOID:005068600.022
disease of anatomical entityDOID:700.020
disease of mental healthDOID:15000.018
intellectual disabilityDOID:105900.018
developmental disorder of mental healthDOID:006003700.018
specific developmental disorderDOID:006003800.018
musculoskeletal system diseaseDOID:1700.011