Drosophila melanogaster

15 known processes

Fen1 (Dmel_CG8648)

Flap endonuclease 1

(Aliases: DmFEN-1,CG8648,EG:EG0003.3,FEN1,Dmel\CG8648)

Fen1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
nuclear divisionGO:00002803320.439
chromosome organizationGO:00512763600.271
telomere maintenanceGO:0000723210.216
organelle fissionGO:00482853400.203
negative regulation of nucleobase containing compound metabolic processGO:00459342610.188
telomere organizationGO:0032200210.185
dna replicationGO:0006260480.181
negative regulation of cellular metabolic processGO:00313243820.169
cellular protein modification processGO:00064644380.153
negative regulation of nitrogen compound metabolic processGO:00511722650.146
negative regulation of transcription dna templatedGO:00458922370.132
dna metabolic processGO:00062592270.131
dna recombinationGO:0006310320.127
protein modification processGO:00362114380.122
macromolecular complex assemblyGO:00650032560.121
dna conformation changeGO:00711031050.110
anatomical structure homeostasisGO:0060249970.096
negative regulation of gene expressionGO:00106293870.094
positive regulation of macromolecule metabolic processGO:00106044050.089
negative regulation of cellular biosynthetic processGO:00313272770.087
programmed cell deathGO:00125012570.084
negative regulation of nucleic acid templated transcriptionGO:19035072400.075
cell cycle checkpointGO:0000075950.074
cellular response to dna damage stimulusGO:00069742230.074
cell deathGO:00082192790.074
cytoplasmic microtubule organizationGO:0031122220.071
positive regulation of nitrogen compound metabolic processGO:00511733540.067
regulation of apoptotic processGO:00429811300.067
positive regulation of nucleobase containing compound metabolic processGO:00459353320.067
deathGO:00162652840.063
negative regulation of biosynthetic processGO:00098902770.063
positive regulation of cellular biosynthetic processGO:00313283160.060
chromatin modificationGO:00165681470.058
apoptotic processGO:00069151590.058
larval developmentGO:00021641040.056
sister chromatid segregationGO:0000819920.056
small molecule metabolic processGO:00442813050.055
peptidyl amino acid modificationGO:00181931050.055
regulation of protein metabolic processGO:00512462560.052
microtubule cytoskeleton organization involved in mitosisGO:1902850520.052
homeostatic processGO:00425921990.051
positive regulation of macromolecule biosynthetic processGO:00105572830.051
positive regulation of cellular protein metabolic processGO:00322701180.050
negative regulation of rna metabolic processGO:00512532510.050
embryo development ending in birth or egg hatchingGO:00097921520.049
cell cycle dna replicationGO:0044786230.046
negative regulation of rna biosynthetic processGO:19026792400.046
histone modificationGO:00165701060.046
spindle organizationGO:00070512530.044
gene silencingGO:00164581380.043
nuclear dna replicationGO:003326010.043
dna packagingGO:0006323910.043
dna integrity checkpointGO:0031570810.042
positive regulation of multicellular organismal processGO:00512401430.041
organonitrogen compound metabolic processGO:19015643180.040
mitotic nuclear divisionGO:00070672130.039
phosphorylationGO:00163102940.039
regulation of catalytic activityGO:00507901850.038
dna dependent dna replicationGO:0006261170.038
single organism biosynthetic processGO:00447112060.038
protein modification by small protein conjugation or removalGO:00706471060.037
positive regulation of biosynthetic processGO:00098913160.036
regulation of cell cycle phase transitionGO:19019871300.036
regulation of catabolic processGO:00098941700.034
chromatin organizationGO:00063252070.034
regulation of molecular functionGO:00650092170.034
agingGO:00075681430.034
positive regulation of nucleic acid templated transcriptionGO:19035082660.033
regulation of programmed cell deathGO:00430671520.033
mitotic spindle organizationGO:00070522200.032
transcription from rna polymerase ii promoterGO:00063663680.031
chromosome segregationGO:00070591570.031
regulation of cellular protein metabolic processGO:00322682430.031
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.030
positive regulation of rna metabolic processGO:00512542710.029
cell cycle g1 s phase transitionGO:0044843310.028
positive regulation of developmental growthGO:0048639620.028
protein localizationGO:00081042840.028
negative regulation of cell deathGO:0060548810.027
mitotic cell cycle phase transitionGO:00447721380.027
positive regulation of catalytic activityGO:00430851180.027
carboxylic acid metabolic processGO:0019752920.026
negative regulation of macromolecule biosynthetic processGO:00105582700.026
mitotic cell cycle checkpointGO:0007093880.026
positive regulation of gene expressionGO:00106282900.026
multicellular organismal agingGO:00102591400.025
response to endogenous stimulusGO:00097191190.025
determination of adult lifespanGO:00083401370.024
covalent chromatin modificationGO:00165691060.024
regulation of cell cycle processGO:00105641810.024
regulation of cell deathGO:00109411730.024
organic acid metabolic processGO:00060821030.024
regulation of cell cycleGO:00517262910.024
regulation of cell differentiationGO:00455953020.023
positive regulation of rna biosynthetic processGO:19026802660.023
positive regulation of transcription dna templatedGO:00458932660.023
establishment or maintenance of cell polarityGO:00071631670.023
positive regulation of growthGO:0045927750.023
body morphogenesisGO:001017120.022
positive regulation of protein metabolic processGO:00512471280.022
regulation of organelle organizationGO:00330431960.021
vesicle mediated transportGO:00161923810.021
chromatin remodelingGO:0006338720.021
response to biotic stimulusGO:00096072940.020
regulation of cell developmentGO:00602842150.020
oxoacid metabolic processGO:00434361030.020
negative regulation of protein metabolic processGO:0051248850.020
developmental growthGO:00485892800.020
regulation of gene expression epigeneticGO:00400291280.020
tissue morphogenesisGO:00487292970.020
positive regulation of molecular functionGO:00440931360.019
regulation of cellular catabolic processGO:00313291570.019
phagocytosisGO:00069092150.019
cellular macromolecular complex assemblyGO:00346221530.019
regulation of dna metabolic processGO:0051052340.019
regulation of mitotic cell cycleGO:00073461900.019
protein dna complex assemblyGO:0065004630.019
protein modification by small protein conjugationGO:0032446790.019
regulation of growthGO:00400082330.018
amine metabolic processGO:0009308120.018
protein complex assemblyGO:00064612000.018
regulation of phosphate metabolic processGO:00192202100.018
enzyme linked receptor protein signaling pathwayGO:00071671790.018
protein phosphorylationGO:00064681690.017
regulation of hydrolase activityGO:0051336970.017
regulation of multicellular organismal developmentGO:20000264140.017
negative regulation of programmed cell deathGO:0043069720.017
regulation of cell divisionGO:0051302720.017
organophosphate metabolic processGO:00196371950.017
endocytosisGO:00068973100.016
positive regulation of multicellular organism growthGO:0040018210.016
positive regulation of signal transductionGO:00099672230.016
telomere cappingGO:0016233110.016
cellular response to chemical stimulusGO:00708871990.016
intracellular transportGO:00469072280.016
cellular amino acid metabolic processGO:0006520610.016
response to organic substanceGO:00100332840.016
organic substance catabolic processGO:19015753080.016
positive regulation of cellular amino acid metabolic processGO:004576400.016
cytoplasmic transportGO:00164821300.016
cell divisionGO:00513012480.016
circulatory system developmentGO:0072359820.015
appendage developmentGO:00487364010.015
positive regulation of developmental processGO:00510941430.015
nucleoside phosphate metabolic processGO:00067531620.015
negative regulation of gene expression epigeneticGO:0045814770.015
meiosis iGO:0007127590.015
stem cell differentiationGO:00488631170.015
spindle assemblyGO:0051225800.015
response to oxygen containing compoundGO:19017002000.015
regulation of cellular amino acid metabolic processGO:000652100.015
morphogenesis of an epitheliumGO:00020092760.015
regulation of phosphorus metabolic processGO:00511742100.014
meiotic cell cycle processGO:19030461320.014
reciprocal dna recombinationGO:0035825190.014
negative regulation of response to stimulusGO:00485852580.014
cellular protein localizationGO:00346131600.014
cytoskeleton dependent cytokinesisGO:0061640810.014
macromolecule catabolic processGO:00090571610.014
regulation of cellular amine metabolic processGO:003323830.014
embryonic morphogenesisGO:00485982060.014
mitotic dna integrity checkpointGO:0044774750.013
nucleotide metabolic processGO:00091171610.013
negative regulation of cellular protein metabolic processGO:0032269850.013
regulation of cellular ketone metabolic processGO:001056530.013
growthGO:00400073590.013
reciprocal meiotic recombinationGO:0007131190.013
cell cycle phase transitionGO:00447701400.013
cellular catabolic processGO:00442483720.013
regulation of nervous system developmentGO:00519602480.013
regulation of mitotic cell cycle phase transitionGO:19019901300.013
regulation of developmental growthGO:00486381740.013
negative regulation of signalingGO:00230572190.013
protein alkylationGO:0008213430.013
regulation of protein deacetylationGO:009031120.013
g1 s transition of mitotic cell cycleGO:0000082310.013
adult behaviorGO:00305341370.012
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.012
negative regulation of cell communicationGO:00106482230.012
multicellular organism growthGO:0035264460.012
dna damage checkpointGO:0000077780.012
nucleobase containing small molecule metabolic processGO:00550861740.012
positive regulation of hydrolase activityGO:0051345780.012
mitotic dna damage checkpointGO:0044773740.012
cellular ketone metabolic processGO:0042180240.012
recombinational repairGO:0000725130.012
regulation of transcription from rna polymerase ii promoterGO:00063573780.012
response to oxidative stressGO:0006979860.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.012
regulation of multicellular organism growthGO:0040014400.011
nuclear importGO:0051170510.011
positive regulation of programmed cell deathGO:0043068620.011
eye developmentGO:00016543230.011
negative regulation of signal transductionGO:00099682060.011
protein ubiquitinationGO:0016567700.011
embryonic hindgut morphogenesisGO:0048619480.011
organic substance transportGO:00717022570.011
spindle assembly involved in mitosisGO:0090307500.011
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.011
cellular response to endogenous stimulusGO:0071495800.011
organic cyclic compound catabolic processGO:19013611680.011
cytokinesisGO:0000910900.011
regulation of triglyceride catabolic processGO:001089610.011
gonad developmentGO:0008406500.011
histone mrna metabolic processGO:000833480.011
purine nucleotide metabolic processGO:00061631460.011
cell proliferationGO:00082832990.010
mitotic chromosome condensationGO:0007076220.010
negative regulation of proteolysisGO:0045861310.010
regulation of cellular component biogenesisGO:00440872010.010
positive regulation of cellular component biogenesisGO:0044089800.010
purine containing compound metabolic processGO:00725211550.010
protein localization to organelleGO:0033365820.010
small gtpase mediated signal transductionGO:0007264880.010

Fen1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org