Drosophila melanogaster

65 known processes

5-HT1A (Dmel_CG16720)

Serotonin receptor 1A

(Aliases: 5HT[[1ADro]],5HT1A,DRO2A,5-HT[[1ADro]],Dmel\CG16720,Dm5HTdro2A,5-HT-dro2A,CG16720,5-HT1ADro,5HT-dro2A,5htdro2a,5-HT[1A]Dro,5HT-R2A,d5-HT1A,5HT-drp[[2A]])

5-HT1A biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
camp biosynthetic processGO:0006171170.815
response to abiotic stimulusGO:00096283410.739
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188170.706
response to temperature stimulusGO:00092661060.626
learning or memoryGO:00076111410.589
cyclic nucleotide metabolic processGO:0009187280.486
g protein coupled receptor signaling pathwayGO:00071861360.476
neurological system processGO:00508773580.437
male mating behaviorGO:0060179700.367
single organism behaviorGO:00447083910.344
sensory perceptionGO:00076001960.265
associative learningGO:0008306650.261
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187170.260
response to oxygen containing compoundGO:19017002000.259
multi organism behaviorGO:00517051750.247
regulation of camp metabolic processGO:0030814120.239
male courtship behaviorGO:0008049630.236
behavioral response to ethanolGO:0048149490.222
olfactory learningGO:0008355560.211
olfactory behaviorGO:0042048970.208
organonitrogen compound metabolic processGO:19015643180.193
cyclic nucleotide biosynthetic processGO:0009190250.189
neuropeptide signaling pathwayGO:0007218450.185
adult behaviorGO:00305341370.178
multi organism reproductive behaviorGO:00447051210.177
ribonucleotide biosynthetic processGO:0009260280.167
regulation of purine nucleotide biosynthetic processGO:1900371140.162
regulation of lyase activityGO:0051339140.156
multi multicellular organism processGO:00447061230.156
organonitrogen compound biosynthetic processGO:19015661170.153
purine containing compound biosynthetic processGO:0072522300.151
purine ribonucleotide metabolic processGO:00091501450.149
long term memoryGO:0007616620.148
taxisGO:00423303040.146
learningGO:0007612750.143
mating behaviorGO:00076171060.142
regulation of cyclic nucleotide metabolic processGO:0030799130.137
nucleotide metabolic processGO:00091171610.128
nucleobase containing small molecule metabolic processGO:00550861740.123
cyclic purine nucleotide metabolic processGO:0052652250.122
cognitionGO:00508901410.122
intracellular signal transductionGO:00355563000.117
response to reactive oxygen speciesGO:0000302240.117
positive regulation of biosynthetic processGO:00098913160.116
purine containing compound metabolic processGO:00725211550.113
cellular metal ion homeostasisGO:0006875310.112
chemosensory behaviorGO:00076351060.111
response to alcoholGO:0097305950.109
response to light stimulusGO:00094161240.106
positive regulation of nucleobase containing compound metabolic processGO:00459353320.106
memoryGO:0007613940.105
regulation of nucleotide metabolic processGO:0006140620.104
response to organic substanceGO:00100332840.099
aromatic compound catabolic processGO:00194391660.097
regulation of transcription from rna polymerase ii promoterGO:00063573780.092
nucleotide biosynthetic processGO:0009165340.091
purine ribonucleotide biosynthetic processGO:0009152280.090
positive regulation of nitrogen compound metabolic processGO:00511733540.088
response to external biotic stimulusGO:00432072930.087
positive regulation of cellular biosynthetic processGO:00313283160.087
purine nucleotide metabolic processGO:00061631460.086
nucleoside phosphate biosynthetic processGO:1901293340.085
response to radiationGO:00093141550.084
regulation of localizationGO:00328792750.083
small molecule metabolic processGO:00442813050.083
feeding behaviorGO:0007631500.081
post embryonic appendage morphogenesisGO:00351203850.081
forebrain developmentGO:003090020.081
positive regulation of response to stimulusGO:00485843230.080
imaginal disc derived appendage morphogenesisGO:00351143950.079
regulation of catalytic activityGO:00507901850.078
regulation of protein modification processGO:00313991120.075
imaginal disc derived appendage developmentGO:00487373990.074
positive regulation of rna metabolic processGO:00512542710.074
multicellular organismal reproductive behaviorGO:00330571100.073
organophosphate metabolic processGO:00196371950.073
appendage morphogenesisGO:00351073970.071
locomotory behaviorGO:00076261760.070
positive regulation of signalingGO:00230562430.069
regulation of intracellular signal transductionGO:19025312360.068
response to heatGO:0009408630.068
regulation of adenylate cyclase activityGO:0045761120.067
positive regulation of cell communicationGO:00106472500.067
positive regulation of cyclase activityGO:003128190.063
carbohydrate derivative metabolic processGO:19011352170.063
localization of cellGO:00516742570.062
negative regulation of cellular metabolic processGO:00313243820.061
synaptic transmissionGO:00072682880.061
detection of abiotic stimulusGO:0009582660.061
cell migrationGO:00164772380.059
response to inorganic substanceGO:0010035440.059
regulation of multi organism processGO:00439001310.058
negative regulation of gene expressionGO:00106293870.056
regulation of cell cycleGO:00517262910.056
neurotransmitter metabolic processGO:004213320.056
response to oxidative stressGO:0006979860.055
courtship behaviorGO:0007619680.055
matingGO:00076181200.055
negative regulation of cell communicationGO:00106482230.054
purine nucleotide biosynthetic processGO:0006164290.053
positive regulation of adenylate cyclase activity involved in g protein coupled receptor signaling pathwayGO:001057970.053
ribose phosphate biosynthetic processGO:0046390280.053
ribose phosphate metabolic processGO:00196931450.052
wing disc morphogenesisGO:00074723440.052
appendage developmentGO:00487364010.051
cellular response to oxygen containing compoundGO:1901701790.051
nucleoside phosphate metabolic processGO:00067531620.051
calcium ion homeostasisGO:0055074230.050
negative regulation of nucleobase containing compound metabolic processGO:00459342610.050
positive regulation of nucleic acid templated transcriptionGO:19035082660.050
regulation of camp biosynthetic processGO:0030817120.049
inter male aggressive behaviorGO:0002121600.049
positive regulation of rna biosynthetic processGO:19026802660.049
regulation of nucleotide biosynthetic processGO:0030808140.049
telencephalon developmentGO:002153720.049
regulation of molecular functionGO:00650092170.048
transcription from rna polymerase ii promoterGO:00063663680.047
response to bacteriumGO:00096171980.047
regulation of cell deathGO:00109411730.046
positive regulation of lyase activityGO:0051349100.046
organophosphate biosynthetic processGO:0090407460.046
neuromuscular synaptic transmissionGO:0007274670.046
regulation of phosphate metabolic processGO:00192202100.046
carbohydrate derivative biosynthetic processGO:1901137850.045
enzyme linked receptor protein signaling pathwayGO:00071671790.044
cell adhesionGO:00071551360.044
camp metabolic processGO:0046058190.044
positive regulation of macromolecule biosynthetic processGO:00105572830.043
response to ionizing radiationGO:0010212320.043
eye morphogenesisGO:00485922600.042
mapk cascadeGO:00001651070.041
divalent inorganic cation homeostasisGO:0072507290.041
regulation of adenylate cyclase activity involved in g protein coupled receptor signaling pathwayGO:001057880.041
regulation of phosphorus metabolic processGO:00511742100.040
cellular response to heatGO:0034605240.040
regulation of anatomical structure morphogenesisGO:00226032420.039
positive regulation of cellular component biogenesisGO:0044089800.039
organic substance transportGO:00717022570.039
negative regulation of response to stimulusGO:00485852580.039
cellular response to chemical stimulusGO:00708871990.039
cellular amine metabolic processGO:0044106120.039
positive regulation of cyclic nucleotide metabolic processGO:003080190.038
regulation of response to stressGO:00801342000.037
regulation of purine nucleotide metabolic processGO:1900542620.037
cellular amino acid metabolic processGO:0006520610.037
negative regulation of cellular biosynthetic processGO:00313272770.037
positive regulation of cellular component organizationGO:00511301560.037
cellular catabolic processGO:00442483720.036
phosphorylationGO:00163102940.036
amine metabolic processGO:0009308120.036
ribonucleotide metabolic processGO:00092591450.035
thermotaxisGO:0043052160.035
sleepGO:0030431490.035
ribonucleoside triphosphate metabolic processGO:00091991190.035
central nervous system developmentGO:00074172010.035
response to ethanolGO:0045471590.035
dna metabolic processGO:00062592270.035
positive regulation of phosphate metabolic processGO:00459371390.035
negative regulation of nitrogen compound metabolic processGO:00511722650.034
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.034
energy taxisGO:0009453210.034
epithelial cell migrationGO:00106311480.033
cellular nitrogen compound catabolic processGO:00442701650.033
anesthesia resistant memoryGO:000761560.033
regulation of locomotionGO:0040012420.033
signal transduction by phosphorylationGO:00230141070.033
r7 cell differentiationGO:0045466430.032
negative regulation of biosynthetic processGO:00098902770.032
rhythmic processGO:00485111060.032
regulation of cellular ketone metabolic processGO:001056530.032
purine nucleotide catabolic processGO:00061951090.032
positive regulation of macromolecule metabolic processGO:00106044050.032
regulation of apoptotic processGO:00429811300.032
response to starvationGO:0042594970.031
protein phosphorylationGO:00064681690.031
organic cyclic compound catabolic processGO:19013611680.031
peptide metabolic processGO:0006518800.030
regulation of cell substrate adhesionGO:001081020.030
ion homeostasisGO:0050801550.030
positive regulation of signal transductionGO:00099672230.030
positive regulation of transcription dna templatedGO:00458932660.029
endocytosisGO:00068973100.029
regulation of gene expression epigeneticGO:00400291280.029
axonogenesisGO:00074092900.029
adult locomotory behaviorGO:0008344760.029
organic substance catabolic processGO:19015753080.029
cell divisionGO:00513012480.029
single organism biosynthetic processGO:00447112060.028
vesicle mediated transportGO:00161923810.028
detection of light stimulusGO:0009583580.028
developmental maturationGO:00217001720.028
regulation of response to external stimulusGO:00321011150.028
reproductive behaviorGO:00190981220.028
neuron projection guidanceGO:00974852410.028
positive regulation of molecular functionGO:00440931360.028
divalent inorganic cation transportGO:0072511300.027
secretionGO:00469031090.027
regulation of cyclic nucleotide biosynthetic processGO:0030802130.027
imaginal disc derived wing morphogenesisGO:00074763370.027
protein localizationGO:00081042840.027
regulation of cellular catabolic processGO:00313291570.027
positive regulation of phosphorus metabolic processGO:00105621390.027
regulation of cellular amine metabolic processGO:003323830.027
positive regulation of nucleotide biosynthetic processGO:0030810100.027
rna processingGO:00063961470.027
single organism catabolic processGO:00447122280.027
positive regulation of camp biosynthetic processGO:003081980.026
cell motilityGO:00488702510.026
response to organonitrogen compoundGO:0010243750.026
detection of stimulusGO:00516061560.026
axon guidanceGO:00074112330.025
cellular response to carbohydrate stimulusGO:007132240.025
regionalizationGO:00030024160.025
negative regulation of phosphorus metabolic processGO:0010563450.025
regulation of cell cycle processGO:00105641810.025
mrna metabolic processGO:00160711240.025
protein modification processGO:00362114380.024
regulation of growthGO:00400082330.024
segmentationGO:00352822070.024
cellular cation homeostasisGO:0030003380.024
ribonucleotide catabolic processGO:00092611090.024
regulation of protein metabolic processGO:00512462560.024
regulation of mitotic cell cycleGO:00073461900.024
chromatin modificationGO:00165681470.024
anatomical structure homeostasisGO:0060249970.024
negative regulation of developmental growthGO:0048640640.023
nucleobase containing compound catabolic processGO:00346551650.023
negative regulation of transcription dna templatedGO:00458922370.023
oxoacid metabolic processGO:00434361030.023
response to sterolGO:0036314340.023
carboxylic acid metabolic processGO:0019752920.023
negative regulation of rna biosynthetic processGO:19026792400.023
regulation of cellular protein metabolic processGO:00322682430.023
response to other organismGO:00517072930.022
regulation of synaptic plasticityGO:0048167140.022
phenol containing compound metabolic processGO:0018958570.022
cellular divalent inorganic cation homeostasisGO:0072503230.022
regulation of catabolic processGO:00098941700.022
cellular response to ionizing radiationGO:0071479150.021
response to organic cyclic compoundGO:0014070890.021
negative regulation of nucleic acid templated transcriptionGO:19035072400.021
sensory organ morphogenesisGO:00905962600.021
immune responseGO:00069552460.021
regulation of programmed cell deathGO:00430671520.021
positive regulation of protein metabolic processGO:00512471280.020
cellular protein modification processGO:00064644380.020
positive regulation of cell migrationGO:003033520.020
cell proliferationGO:00082832990.020
negative regulation of signalingGO:00230572190.020
epithelium migrationGO:00901321480.020
muscle system processGO:0003012210.020
apoptotic processGO:00069151590.020
inorganic ion transmembrane transportGO:0098660730.019
response to endogenous stimulusGO:00097191190.019
defense responseGO:00069523000.019
positive regulation of apoptotic processGO:0043065470.019
flight behaviorGO:0007629260.019
ameboidal type cell migrationGO:00016671510.019
chromosome organizationGO:00512763600.019
positive regulation of purine nucleotide metabolic processGO:1900544550.019
nucleotide catabolic processGO:00091661090.019
sensory perception of mechanical stimulusGO:0050954720.019
wnt signaling pathwayGO:0016055980.019
heterocycle catabolic processGO:00467001660.019
establishment of localization in cellGO:00516494020.018
ras protein signal transductionGO:0007265880.018
transmembrane transportGO:00550851390.018
response to biotic stimulusGO:00096072940.018
detection of external stimulusGO:0009581660.018
negative regulation of multicellular organismal processGO:00512411420.018
chemotaxisGO:00069352490.018
signal releaseGO:0023061490.018
purine nucleoside triphosphate catabolic processGO:00091461080.018
phagocytosisGO:00069092150.018
negative regulation of insulin secretionGO:004667610.018
macromolecular complex assemblyGO:00650032560.018
tube morphogenesisGO:00352391910.018
catabolic processGO:00090564090.018
cellular ion homeostasisGO:0006873390.018
positive regulation of gene expressionGO:00106282900.018
homeostatic processGO:00425921990.017
biological adhesionGO:00226101380.017
regulation of synaptic growth at neuromuscular junctionGO:0008582890.017
deathGO:00162652840.017
regulation of developmental growthGO:00486381740.017
programmed cell deathGO:00125012570.017
neuromuscular junction developmentGO:00075281490.017
neural precursor cell proliferationGO:0061351750.017
septate junction assemblyGO:0019991260.017
positive regulation of phosphorylationGO:0042327870.017
response to nitrogen compoundGO:1901698900.017
divalent metal ion transportGO:0070838260.017
positive regulation of calcium ion transportGO:005192840.017
response to ecdysoneGO:0035075340.017
organonitrogen compound catabolic processGO:19015651280.017
acid secretionGO:004671710.016
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.016
immune response regulating signaling pathwayGO:000276420.016
positive regulation of adenylate cyclase activityGO:004576280.016
eye developmentGO:00016543230.016
embryo development ending in birth or egg hatchingGO:00097921520.016
positive regulation of catalytic activityGO:00430851180.016
regulation of cellular component movementGO:0051270420.016
purine nucleoside triphosphate metabolic processGO:00091441190.016
regulation of cellular amino acid metabolic processGO:000652100.016
mesenchymal cell differentiationGO:004876210.015
positive regulation of hydrolase activityGO:0051345780.015
purine ribonucleoside catabolic processGO:00461301120.015
ion transportGO:00068111450.015
tissue migrationGO:00901301550.015
regulation of transferase activityGO:0051338580.015
negative regulation of cell proliferationGO:0008285690.015
regulation of cell morphogenesisGO:00226041630.015
purine containing compound catabolic processGO:00725231120.015
axon developmentGO:00615642970.015
alternative mrna splicing via spliceosomeGO:0000380600.015
negative regulation of growthGO:0045926840.015
nucleoside phosphate catabolic processGO:19012921100.015
mrna processingGO:00063971040.015
ribonucleoside triphosphate catabolic processGO:00092031080.015
regulation of mapk cascadeGO:0043408920.015
visual learningGO:000854240.015
circadian rhythmGO:00076231050.015
regulation of immune responseGO:00507761180.015
cell projection assemblyGO:0030031940.015
regulation of protein kinase activityGO:0045859510.014
guanosine containing compound catabolic processGO:1901069740.014
neuroblast proliferationGO:0007405740.014
cellular homeostasisGO:0019725800.014
cell cell junction assemblyGO:0007043380.014
adenylate cyclase activating g protein coupled receptor signaling pathwayGO:000718990.014
cation homeostasisGO:0055080510.014
reproductive structure developmentGO:0048608740.014
skeletal muscle organ developmentGO:0060538480.014
response to extracellular stimulusGO:00099911160.014
mitotic cell cycle phase transitionGO:00447721380.014
response to woundingGO:0009611940.014
regulation of nervous system developmentGO:00519602480.014
protein complex assemblyGO:00064612000.014
cellular macromolecule localizationGO:00707272200.014
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.014
leg disc morphogenesisGO:0007478800.014
positive regulation of cell motilityGO:200014730.014
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.014
brain developmentGO:00074201200.014
organic acid metabolic processGO:00060821030.013
developmental growthGO:00485892800.013
regulation of cell proliferationGO:00421271630.013
camera type eye developmentGO:004301040.013
cellular ketone metabolic processGO:0042180240.013
immune response activating signal transductionGO:000275720.013
synapse assemblyGO:00074161430.013
phototaxisGO:0042331210.013
anterior posterior axis specificationGO:00099481090.013
cellular protein localizationGO:00346131600.013
regulation of organelle organizationGO:00330431960.013
protein dna complex subunit organizationGO:0071824860.013
cellular response to abiotic stimulusGO:0071214580.013
cellular chemical homeostasisGO:0055082400.013
response to coldGO:0009409130.013
nucleoside triphosphate metabolic processGO:00091411200.013
maintenance of locationGO:0051235730.013
purine ribonucleoside metabolic processGO:00461281270.013
carbohydrate derivative catabolic processGO:19011361180.013
regulation of cell morphogenesis involved in differentiationGO:0010769610.013
positive regulation of catabolic processGO:00098961050.012
negative regulation of protein modification processGO:0031400290.012
substrate adhesion dependent cell spreadingGO:003444620.012
cellular response to organic substanceGO:00713101320.012
gtp metabolic processGO:0046039720.012
regulation of cellular localizationGO:00603411360.012
regulation of kinase activityGO:0043549530.012
regulation of cell differentiationGO:00455953020.012
positive regulation of cellular protein metabolic processGO:00322701180.012
response to nutrient levelsGO:00316671140.012
synapse organizationGO:00508081960.012
cellular response to biotic stimulusGO:007121640.012
rna splicingGO:0008380830.012
response to decreased oxygen levelsGO:0036293580.012
pigmentationGO:0043473750.012
purine ribonucleoside triphosphate catabolic processGO:00092071080.012
sex differentiationGO:0007548810.012
regulation of multicellular organismal developmentGO:20000264140.012
molting cycle processGO:0022404290.012
cell cycle checkpointGO:0000075950.012
positive regulation of purine nucleotide biosynthetic processGO:1900373100.012
morphogenesis of an epitheliumGO:00020092760.012
positive regulation of intracellular signal transductionGO:19025331160.012
small gtpase mediated signal transductionGO:0007264880.012
protein modification by small protein conjugation or removalGO:00706471060.012
negative regulation of camp biosynthetic processGO:003081830.012
negative regulation of erk1 and erk2 cascadeGO:007037330.012
protein maturationGO:0051604710.011
kidney developmentGO:000182230.011
glycosyl compound metabolic processGO:19016571270.011
histone modificationGO:00165701060.011
open tracheal system developmentGO:00074242040.011
nephron developmentGO:007200630.011
short term memoryGO:0007614190.011
regulation of protein phosphorylationGO:0001932640.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092380.011
negative regulation of synapse assemblyGO:0051964390.011
regulation of response to biotic stimulusGO:0002831630.011
cell cycle phase transitionGO:00447701400.011
female meiotic divisionGO:0007143700.011
negative regulation of rna metabolic processGO:00512532510.011
cell deathGO:00082192790.011
response to oxygen levelsGO:0070482590.011
rhythmic behaviorGO:0007622760.011
calcium ion transportGO:0006816240.011
cellular response to external stimulusGO:0071496660.011
cortical cytoskeleton organizationGO:0030865290.011
nucleoside catabolic processGO:00091641120.011
nuclear divisionGO:00002803320.011
negative regulation of purine nucleotide biosynthetic processGO:190037230.011
chemical homeostasisGO:0048878920.011
positive regulation of cell morphogenesis involved in differentiationGO:0010770120.011
ribonucleoside catabolic processGO:00424541120.011
regulation of phosphorylationGO:00423251470.011
spindle organizationGO:00070512530.011
regulation of transportGO:00510491810.011
regulation of synaptic transmissionGO:0050804690.011
gliogenesisGO:0042063800.011
purine nucleoside catabolic processGO:00061521120.011
reproductive system developmentGO:0061458740.011
cellular response to extracellular stimulusGO:0031668640.011
response to lipopolysaccharideGO:003249640.011
regulation of neurotransmitter levelsGO:0001505380.011
cell maturationGO:00484691440.011
negative regulation of signal transductionGO:00099682060.011
ribonucleoside metabolic processGO:00091191270.011
positive regulation of nervous system developmentGO:0051962690.011
regulation of cellular component biogenesisGO:00440872010.011
regulation of defense responseGO:00313471020.011
amide biosynthetic processGO:0043604420.011
spinal cord developmentGO:002151010.010
response to lipidGO:0033993380.010
response to alkaloidGO:0043279260.010
chromosome segregationGO:00070591570.010
social behaviorGO:003517640.010
columnar cuboidal epithelial cell developmentGO:00020662490.010
trna processingGO:000803330.010
chromatin remodelingGO:0006338720.010
negative regulation of macromolecule biosynthetic processGO:00105582700.010
compound eye developmentGO:00487493070.010
muscle contractionGO:0006936130.010

5-HT1A disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.016
disease of anatomical entityDOID:700.016
central nervous system diseaseDOID:33100.015
disease of cellular proliferationDOID:1456600.014
organ system cancerDOID:005068600.012
cancerDOID:16200.012