Drosophila melanogaster

39 known processes

Cdk4 (Dmel_CG5072)

Cyclin-dependent kinase 4

(Aliases: l(2)k06503,dCdk4,Pk53C,CG5072,l(2)sh0671,DmCdk4,cdk,CDK4/6,Cdk4/6,l(2)0671,l(2)05428,CDK4,cdk4/6,cdk4,l(2)s4639,Pk?7,8-6,Dmel\CG5072)

Cdk4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
mitotic g2 m transition checkpointGO:0044818700.931
mitotic dna damage checkpointGO:0044773740.861
mitotic cell cycle phase transitionGO:00447721380.833
Human Worm
mitotic dna integrity checkpointGO:0044774750.688
regulation of cell cycle phase transitionGO:19019871300.608
Human Worm
growthGO:00400073590.534
regulation of phosphorus metabolic processGO:00511742100.533
cellular response to organic substanceGO:00713101320.455
regulation of g1 s transition of mitotic cell cycleGO:2000045230.447
Worm
mitotic g2 dna damage checkpointGO:0007095690.444
negative regulation of cell cycle phase transitionGO:19019881030.441
cell cycle g1 s phase transitionGO:0044843310.433
Human Worm
epithelial cell developmentGO:00020642740.396
Human
regulation of cell cycleGO:00517262910.385
Human Mouse Worm
eye morphogenesisGO:00485922600.378
neuronal stem cell divisionGO:0036445350.347
cell divisionGO:00513012480.330
regulation of phosphorylationGO:00423251470.313
regulation of growthGO:00400082330.313
positive regulation of macromolecule biosynthetic processGO:00105572830.306
cell cycle phase transitionGO:00447701400.305
Human Worm
neuroblast divisionGO:0055057350.305
regulation of transcription from rna polymerase ii promoterGO:00063573780.303
regulation of phosphate metabolic processGO:00192202100.302
immune system processGO:00023763470.295
Human Mouse
positive regulation of cellular biosynthetic processGO:00313283160.283
regulation of cell differentiationGO:00455953020.280
Human
regulation of nervous system developmentGO:00519602480.272
regulation of developmental growthGO:00486381740.268
regulation of imaginal disc derived wing sizeGO:0044719200.268
somatic stem cell divisionGO:0048103370.267
positive regulation of cell cycle g2 m phase transitionGO:190275120.251
Human
developmental growthGO:00485892800.248
phosphorylationGO:00163102940.239
Human Mouse
positive regulation of gene expressionGO:00106282900.234
Mouse
regulation of epithelial cell proliferationGO:005067840.232
Human
reproductive structure developmentGO:0048608740.231
Worm
positive regulation of lipid catabolic processGO:005099610.230
negative regulation of cell cycle processGO:00109481090.229
Human
digestive system developmentGO:00551231490.223
positive regulation of phosphorylationGO:0042327870.212
regulation of multicellular organism growthGO:0040014400.212
macromolecule catabolic processGO:00090571610.210
regulation of cell cycle processGO:00105641810.210
Human Worm
cellular response to endogenous stimulusGO:0071495800.209
positive regulation of g2 m transition of mitotic cell cycleGO:001097120.199
Human
regulation of cell cycle g1 s phase transitionGO:1902806230.197
Worm
localization of cellGO:00516742570.197
negative regulation of mitotic cell cycleGO:00459301090.195
tube morphogenesisGO:00352391910.195
mitochondrion organizationGO:0007005650.193
neural precursor cell proliferationGO:0061351750.191
dna replicationGO:0006260480.187
regulation of mitotic cell cycle phase transitionGO:19019901300.183
Human Worm
regulation of wnt signaling pathwayGO:0030111680.181
negative regulation of mitotic cell cycle phase transitionGO:19019911030.180
mitotic cell cycle checkpointGO:0007093880.180
negative regulation of response to stimulusGO:00485852580.179
Human
positive regulation of biosynthetic processGO:00098913160.178
positive regulation of protein metabolic processGO:00512471280.172
establishment of localization in cellGO:00516494020.172
cell migrationGO:00164772380.171
anterior posterior pattern specificationGO:00099521360.161
protein modification processGO:00362114380.159
Human Mouse
positive regulation of developmental processGO:00510941430.158
forebrain developmentGO:003090020.149
negative regulation of developmental growthGO:0048640640.148
organic acid transportGO:0015849180.147
camera type eye morphogenesisGO:004859320.144
limb developmentGO:006017310.137
cell proliferationGO:00082832990.137
stem cell differentiationGO:00488631170.135
Mouse
periodic partitioningGO:0007365290.134
regulation of protein phosphorylationGO:0001932640.134
hematopoietic or lymphoid organ developmentGO:0048534570.132
Human Mouse
gonad developmentGO:0008406500.132
Worm
positive regulation of multicellular organismal processGO:00512401430.131
regulation of protein serine threonine kinase activityGO:0071900250.129
regulation of cellular ketone metabolic processGO:001056530.127
negative regulation of g1 s transition of mitotic cell cycleGO:2000134130.125
negative regulation of cell cycle g1 s phase transitionGO:1902807130.122
chromosome organizationGO:00512763600.121
regulation of protein kinase activityGO:0045859510.119
response to organic substanceGO:00100332840.119
g2 dna damage checkpointGO:0031572690.118
dna packagingGO:0006323910.117
g1 s transition of mitotic cell cycleGO:0000082310.115
Human Worm
cellular amine metabolic processGO:0044106120.115
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.114
ion transportGO:00068111450.113
cytoplasmic transportGO:00164821300.111
gastrulation involving germ band extensionGO:0010004360.109
positive regulation of molecular functionGO:00440931360.107
asymmetric neuroblast divisionGO:0055059330.106
positive regulation of protein phosphorylationGO:0001934340.104
positive regulation of nucleic acid templated transcriptionGO:19035082660.104
anatomical structure homeostasisGO:0060249970.103
positive regulation of rna biosynthetic processGO:19026802660.103
dna double strand break processingGO:000072930.101
regulation of immune system processGO:00026821760.099
Human
protein catabolic processGO:00301631010.098
cell cell signaling involved in cell fate commitmentGO:00451682100.098
positive regulation of protein kinase activityGO:0045860250.097
eggshell chorion gene amplificationGO:000730790.095
posttranscriptional regulation of gene expressionGO:00106081450.094
response to x rayGO:001016580.090
protein maturationGO:0051604710.090
positive regulation of phosphate metabolic processGO:00459371390.089
negative regulation of cell differentiationGO:00455961430.089
Human
single organism biosynthetic processGO:00447112060.088
cellular protein modification processGO:00064644380.088
Human Mouse
mitotic nuclear divisionGO:00070672130.088
Worm
cell cycle dna replicationGO:0044786230.086
positive regulation of nitrogen compound metabolic processGO:00511733540.085
positive regulation of growthGO:0045927750.085
nuclear divisionGO:00002803320.085
Worm
positive regulation of transportGO:0051050920.083
positive regulation of cellular protein metabolic processGO:00322701180.083
nuclear dna replicationGO:003326010.082
asymmetric stem cell divisionGO:0098722490.081
gland developmentGO:00487321910.080
regulation of intracellular signal transductionGO:19025312360.080
positive regulation of rna metabolic processGO:00512542710.079
protein phosphorylationGO:00064681690.078
Human Mouse
regulation of multicellular organismal developmentGO:20000264140.077
Human
regulation of immune responseGO:00507761180.077
negative regulation of wnt signaling pathwayGO:0030178280.074
negative regulation of phosphorylationGO:0042326350.074
positive regulation of catalytic activityGO:00430851180.073
gastrulation with mouth forming firstGO:0001703360.072
immune responseGO:00069552460.070
olfactory learningGO:0008355560.070
regulation of kinase activityGO:0043549530.070
neutral lipid catabolic processGO:004646130.069
body morphogenesisGO:001017120.069
Worm
cell motilityGO:00488702510.069
intracellular transportGO:00469072280.068
protein palmitoylationGO:001834520.067
transcription from rna polymerase ii promoterGO:00063663680.066
cellular response to oxygen containing compoundGO:1901701790.065
chemosensory behaviorGO:00076351060.065
cellular response to dna damage stimulusGO:00069742230.064
positive regulation of cell cycleGO:0045787430.063
Human Worm
organelle fissionGO:00482853400.062
Worm
negative regulation of cell cycleGO:00457861160.062
Human
purine nucleotide metabolic processGO:00061631460.062
stem cell divisionGO:0017145690.062
response to external biotic stimulusGO:00432072930.061
Human
wnt signaling pathwayGO:0016055980.061
regionalizationGO:00030024160.061
stem cell proliferationGO:0072089880.061
positive regulation of programmed cell deathGO:0043068620.061
embryonic morphogenesisGO:00485982060.060
cellular response to nitrogen compoundGO:1901699510.060
g2 m transition of mitotic cell cycleGO:0000086190.060
Human
regulation of protein modification processGO:00313991120.059
hindbrain developmentGO:003090220.059
protein localizationGO:00081042840.059
response to endogenous stimulusGO:00097191190.059
chromatin modificationGO:00165681470.058
organic substance transportGO:00717022570.058
ensheathment of neuronsGO:0007272100.057
single organism intracellular transportGO:19025822070.057
urogenital system developmentGO:0001655720.056
regulation of transferase activityGO:0051338580.056
positive regulation of phosphorus metabolic processGO:00105621390.055
homeostatic processGO:00425921990.054
Human
signal transduction by phosphorylationGO:00230141070.054
ubiquitin dependent protein catabolic processGO:0006511780.054
response to organonitrogen compoundGO:0010243750.054
cellular response to chemical stimulusGO:00708871990.054
modification dependent macromolecule catabolic processGO:0043632790.053
proteolysis involved in cellular protein catabolic processGO:0051603830.053
response to ionizing radiationGO:0010212320.052
cellular response to hormone stimulusGO:0032870440.052
response to insulinGO:0032868290.052
protein ubiquitinationGO:0016567700.052
positive regulation of cellular component organizationGO:00511301560.052
response to nitrogen compoundGO:1901698900.052
neuroblast proliferationGO:0007405740.051
rna cappingGO:003626010.051
regulation of sister chromatid cohesionGO:000706320.051
dna damage checkpointGO:0000077780.051
tube developmentGO:00352952440.050
negative regulation of multicellular organismal processGO:00512411420.050
Human
regulation of response to stressGO:00801342000.050
Human
regulation of cellular protein metabolic processGO:00322682430.050
regulation of anatomical structure sizeGO:00900661630.050
sex differentiationGO:0007548810.049
Worm
morphogenesis of a branching epitheliumGO:0061138450.049
regulation of mapk cascadeGO:0043408920.049
dna metabolic processGO:00062592270.047
regulation of cell divisionGO:0051302720.047
positive regulation of response to stimulusGO:00485843230.047
negative regulation of cellular metabolic processGO:00313243820.046
positive regulation of kinase activityGO:0033674250.046
taxisGO:00423303040.046
nucleoside phosphate metabolic processGO:00067531620.045
meiosis iGO:0007127590.045
positive regulation of protein serine threonine kinase activityGO:0071902150.045
cellular protein catabolic processGO:0044257830.044
peptidyl threonine phosphorylationGO:001810720.044
cell activationGO:000177590.044
Mouse
peptidyl threonine modificationGO:001821030.044
morphogenesis of a branching structureGO:0001763450.043
negative regulation of signalingGO:00230572190.043
response to abiotic stimulusGO:00096283410.043
positive regulation of cell migrationGO:003033520.042
regulation of cyclin dependent protein serine threonine kinase activityGO:000007930.041
cellular ketone metabolic processGO:0042180240.041
development of primary female sexual characteristicsGO:0046545120.041
digestive tract developmentGO:00485651490.041
post embryonic appendage morphogenesisGO:00351203850.040
neuron fate specificationGO:0048665120.040
neuron projection guidanceGO:00974852410.040
eye developmentGO:00016543230.040
nucleoside catabolic processGO:00091641120.040
chromosome segregationGO:00070591570.039
regulation of cellular amino acid metabolic processGO:000652100.039
intracellular protein transportGO:00068861040.039
positive regulation of protein modification processGO:0031401580.039
positive regulation of immune responseGO:0050778630.039
epithelial cell differentiationGO:00308553220.039
Human
dna dependent dna replicationGO:0006261170.039
olfactory behaviorGO:0042048970.039
germ cell migrationGO:0008354430.038
gastrulationGO:0007369700.038
purine nucleoside triphosphate metabolic processGO:00091441190.038
cation transportGO:00068121100.038
amino acid transportGO:0006865120.037
epithelial tube morphogenesisGO:0060562880.037
peptidyl amino acid modificationGO:00181931050.037
deathGO:00162652840.037
maintenance of gastrointestinal epitheliumGO:003027730.037
phosphorylation of rna polymerase ii c terminal domainGO:007081610.036
morphogenesis of an epitheliumGO:00020092760.036
cellular amide metabolic processGO:0043603800.035
synapse assemblyGO:00074161430.035
modification dependent protein catabolic processGO:0019941780.035
regulation of molecular functionGO:00650092170.035
spinal cord patterningGO:002151110.035
regulation of canonical wnt signaling pathwayGO:0060828150.035
embryo development ending in birth or egg hatchingGO:00097921520.034
Worm
carboxylic acid transportGO:0046942180.034
asymmetric cell divisionGO:0008356370.034
chromatin organizationGO:00063252070.034
defense response to bacteriumGO:00427421780.034
synaptic growth at neuromuscular junctionGO:00511241190.033
regulation of cysteine type endopeptidase activityGO:2000116270.033
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.033
response to peptide hormoneGO:0043434290.033
positive regulation of signal transductionGO:00099672230.033
regulation of protein stabilityGO:0031647430.033
positive regulation of stem cell differentiationGO:200073830.032
positive regulation of developmental growthGO:0048639620.032
hemopoiesisGO:0030097460.032
Human Mouse
cellular macromolecule localizationGO:00707272200.031
nephron morphogenesisGO:007202830.031
cellular response to peptide hormone stimulusGO:0071375280.031
endomitotic cell cycleGO:000711370.030
protein complex assemblyGO:00064612000.030
limb morphogenesisGO:003510810.030
segment polarity determinationGO:0007367250.029
regulation of cellular amine metabolic processGO:003323830.029
columnar cuboidal epithelial cell developmentGO:00020662490.029
Human
positive regulation of feeding behaviorGO:200025380.029
dna integrity checkpointGO:0031570810.029
reproductive system developmentGO:0061458740.029
Worm
cellular response to peptideGO:1901653280.029
dna endoreduplicationGO:0042023220.029
immune effector processGO:0002252980.028
regulation of proteolysisGO:0030162870.028
cellular macromolecule catabolic processGO:00442651360.028
mapk cascadeGO:00001651070.027
purine ribonucleotide metabolic processGO:00091501450.027
regulation of protein import into nucleusGO:0042306280.027
carboxylic acid metabolic processGO:0019752920.027
proteolysisGO:00065081920.027
cell cycle g2 m phase transitionGO:0044839220.027
Human
development of primary sexual characteristicsGO:0045137500.027
Worm
lateral inhibitionGO:00463312060.026
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.026
zygotic determination of anterior posterior axis embryoGO:0007354270.026
positive regulation of cellular amino acid metabolic processGO:004576400.026
double strand break repair via synthesis dependent strand annealingGO:004500360.026
inositol lipid mediated signalingGO:004801740.026
organic substance catabolic processGO:19015753080.026
purine containing compound metabolic processGO:00725211550.026
vesicle mediated transportGO:00161923810.026
negative regulation of nitrogen compound metabolic processGO:00511722650.025
amine metabolic processGO:0009308120.025
meiotic cell cycle phase transitionGO:004477140.025
response to radiationGO:00093141550.025
synapse organizationGO:00508081960.025
regulation of i kappab kinase nf kappab signalingGO:004312220.025
regulation of catalytic activityGO:00507901850.025
regulation of intracellular transportGO:0032386640.025
regulation of insulin receptor signaling pathwayGO:0046626170.025
compound eye developmentGO:00487493070.025
enzyme linked receptor protein signaling pathwayGO:00071671790.024
synaptonemal complex organizationGO:007019350.024
innate immune responseGO:00450871440.024
positive regulation of mitotic cell cycle phase transitionGO:1901992200.024
Human Worm
negative regulation of programmed cell deathGO:0043069720.024
programmed cell deathGO:00125012570.024
glycosyl compound metabolic processGO:19016571270.023
positive regulation of signalingGO:00230562430.023
tissue morphogenesisGO:00487292970.023
columnar cuboidal epithelial cell differentiationGO:00020652560.023
Human
cellular lipid metabolic processGO:0044255830.023
negative regulation of growthGO:0045926840.023
protein heterooligomerizationGO:005129140.023
positive regulation of proteolysisGO:0045862520.023
purine nucleoside triphosphate catabolic processGO:00091461080.023
establishment of organelle localizationGO:00516561220.022
axis specificationGO:00097981670.022
somatic muscle developmentGO:0007525660.022
regulation of neural precursor cell proliferationGO:2000177350.022
cell junction organizationGO:0034330570.022
retina development in camera type eyeGO:006004140.022
male gonad developmentGO:000858490.022
sex comb developmentGO:004549880.022
negative regulation of cell proliferationGO:0008285690.022
Human
segmentationGO:00352822070.021
neurological system processGO:00508773580.021
synaptic transmission dopaminergicGO:000196320.021
asymmetric protein localization involved in cell fate determinationGO:004516790.021
response to biotic stimulusGO:00096072940.021
Human
regulation of cell developmentGO:00602842150.021
endocytosisGO:00068973100.021
negative regulation of epithelial cell proliferationGO:005068040.021
Human
response to bacteriumGO:00096171980.021
response to organic cyclic compoundGO:0014070890.021
protein processingGO:0016485680.021
regulation of dna replicationGO:0006275130.021
protein complex biogenesisGO:00702712010.021
regulation of autophagyGO:0010506620.020
positive regulation of transferase activityGO:0051347260.020
branching morphogenesis of an epithelial tubeGO:0048754450.020
fatty acid beta oxidationGO:000663560.020
multicellular organismal agingGO:00102591400.020
development of primary male sexual characteristicsGO:004654690.020
cell cycle arrestGO:000705040.020
Human
smoothened signaling pathwayGO:0007224490.020
cell agingGO:000756920.020
Human
appendage morphogenesisGO:00351073970.020
negative regulation of nucleobase containing compound metabolic processGO:00459342610.020
apoptotic process involved in morphogenesisGO:006056130.019
regulation of neuron differentiationGO:00456641030.019
response to oxygen containing compoundGO:19017002000.019
larval developmentGO:00021641040.019
Worm
secretion by cellGO:00329401010.019
negative regulation of gene expressionGO:00106293870.019
somatic stem cell maintenanceGO:0035019140.019
positive regulation of macromolecule metabolic processGO:00106044050.019
Mouse
proteasomal protein catabolic processGO:0010498590.019
cellular response to oxygen levelsGO:0071453300.019
ribonucleoside catabolic processGO:00424541120.019
transmission of nerve impulseGO:0019226120.019
positive regulation of nucleocytoplasmic transportGO:0046824240.019
peripheral nervous system developmentGO:0007422520.019
dna recombinationGO:0006310320.019
negative regulation of chromosome segregationGO:0051985140.019
response to other organismGO:00517072930.019
Human
positive regulation of cell communicationGO:00106472500.019
regulation of stress activated protein kinase signaling cascadeGO:0070302420.019
regulation of protein catabolic processGO:0042176550.019
positive regulation of cell motilityGO:200014730.018
negative regulation of cell communicationGO:00106482230.018
catabolic processGO:00090564090.018
negative regulation of intracellular signal transductionGO:1902532570.018
defense responseGO:00069523000.018
cuticle developmentGO:0042335860.018
meiotic nuclear divisionGO:00071261510.018
Worm
histone modificationGO:00165701060.018
connective tissue developmentGO:006144830.018
regulation of intracellular protein transportGO:0033157460.018
lipid localizationGO:0010876540.018
regulation of synapse assemblyGO:0051963940.017
apoptotic processGO:00069151590.017
phagocytosisGO:00069092150.017
positive regulation of i kappab kinase nf kappab signalingGO:004312310.016
dorsal ventral pattern formationGO:00099531330.016
cellular catabolic processGO:00442483720.016
spindle organizationGO:00070512530.016
negative regulation of proteolysisGO:0045861310.016
ribonucleotide metabolic processGO:00092591450.016
immune system developmentGO:0002520570.016
Human Mouse
glial cell developmentGO:0021782270.016
positive regulation of transcription dna templatedGO:00458932660.016
germarium derived oocyte fate determinationGO:0007294260.016
hemocyte differentiationGO:0042386380.016
phosphatidylinositol 3 kinase signalingGO:001406540.016
sensory organ morphogenesisGO:00905962600.016
positive regulation of sequence specific dna binding transcription factor activityGO:005109190.015
negative regulation of developmental processGO:00510932010.015
Human
positive regulation of cellular response to insulin stimulusGO:190007840.015
cellular response to organonitrogen compoundGO:0071417360.015
eye antennal disc morphogenesisGO:0007455340.015
negative regulation of phosphate metabolic processGO:0045936450.015
phosphatidylinositol mediated signalingGO:004801540.015
single organism cellular localizationGO:19025801800.015
regulation of mitosisGO:0007088560.015
nephron epithelium morphogenesisGO:007208830.015
dorsal ventral axis specificationGO:0009950660.015
axonogenesisGO:00074092900.015
macromolecular complex assemblyGO:00650032560.015
kidney developmentGO:000182230.015
mesenchymal cell developmentGO:001403110.015
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.015
positive regulation of apoptotic processGO:0043065470.015
regulation of macroautophagyGO:0016241150.015
chromosome separationGO:0051304420.015
protein targetingGO:0006605640.014
regulation of innate immune responseGO:0045088710.014
positive regulation of intracellular transportGO:0032388420.014
single organism catabolic processGO:00447122280.014
camera type eye developmentGO:004301040.014
regulation of mitotic cell cycleGO:00073461900.014
Human Worm
neuronal action potentialGO:0019228100.014
regulation of cell deathGO:00109411730.014
positive regulation of peptidyl tyrosine phosphorylationGO:005073140.014
positive regulation of mapk cascadeGO:0043410630.014
cellular response to transforming growth factor beta stimulusGO:0071560180.014
establishment of protein localizationGO:00451841630.014
immune response activating signal transductionGO:000275720.014
ribonucleoside triphosphate catabolic processGO:00092031080.014
negative regulation of canonical wnt signaling pathwayGO:009009060.014
organonitrogen compound metabolic processGO:19015643180.014
transmembrane transportGO:00550851390.014
regulation of cellular response to stressGO:0080135890.014
Human
response to nutrient levelsGO:00316671140.014
associative learningGO:0008306650.014
retina morphogenesis in camera type eyeGO:006004220.013
regulation of smoothened signaling pathwayGO:0008589280.013
cell fate specificationGO:0001708710.013
positive regulation of cell deathGO:0010942690.013
response to woundingGO:0009611940.013
imaginal disc derived wing morphogenesisGO:00074763370.013
spinal cord dorsal ventral patterningGO:002151310.013
negative regulation of protein modification processGO:0031400290.013
negative regulation of dna dependent dna replicationGO:200010420.013
negative regulation of dna replicationGO:000815670.013
open tracheal system developmentGO:00074242040.013
regulation of organ growthGO:0046620420.013
syncytial blastoderm mitotic cell cycleGO:0035186210.013
regulation of immune effector processGO:0002697520.013
nucleobase containing compound catabolic processGO:00346551650.013
positive regulation of protein transportGO:0051222370.013
nucleocytoplasmic transportGO:0006913720.013
negative regulation of dna metabolic processGO:0051053120.012
single organism nuclear importGO:1902593510.012
chemotaxisGO:00069352490.012
cellular polysaccharide metabolic processGO:0044264110.012
response to metal ionGO:0010038230.012
positive regulation of organ growthGO:0046622120.012
cell growthGO:00160491080.012
cellular lipid catabolic processGO:0044242160.012
organic acid metabolic processGO:00060821030.012
nitrogen compound transportGO:0071705850.012
negative regulation of signal transductionGO:00099682060.012
response to hypoxiaGO:0001666530.012
oocyte maturationGO:000155630.012
genitalia developmentGO:0048806260.012
Worm
dna amplificationGO:0006277110.012
regulation of synaptic growth at neuromuscular junctionGO:0008582890.012
stress activated mapk cascadeGO:0051403520.012
cellular response to insulin stimulusGO:0032869280.012
regulation of cell growthGO:0001558430.012
regulation of chromatin bindingGO:003556130.012
respiratory system developmentGO:00605412130.012
monocarboxylic acid catabolic processGO:0072329100.012
eye antennal disc developmentGO:0035214600.011
insulin like growth factor receptor signaling pathwayGO:004800950.011
purine nucleoside catabolic processGO:00061521120.011
gliogenesisGO:0042063800.011
Human
defense response to other organismGO:00985422250.011
regulation of phosphatase activityGO:001092130.011
positive regulation of wnt signaling pathwayGO:0030177250.011
nephron epithelium developmentGO:007200930.011
cell recognitionGO:00080371020.011
spermatogenesisGO:00072832000.011
anion transmembrane transportGO:0098656260.011
telencephalon developmentGO:002153720.011
enteroendocrine cell differentiationGO:003588310.011
Human

Cdk4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.559
cancerDOID:16200.559
organ system cancerDOID:005068600.203
musculoskeletal system cancerDOID:006010000.043
colorectal cancerDOID:925600.037
gastrointestinal system cancerDOID:311900.037
intestinal cancerDOID:1015500.037
large intestine cancerDOID:567200.037
connective tissue cancerDOID:20100.016
thoracic cancerDOID:509300.014