IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

CG12773 (Dmel_CG12773)

CG12773 gene product from transcript CG12773-RA

(Aliases: Dmel\CG12773,EG:8D8.3)

Entrez: 31082
FLYBASE: FBgn0024365
UniProtKB: M9PDG9
UniProtKB: O46100

Process Predictions
Disease Predictions

CG12773 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

Filter by process size:

Biological process	GO term ID	Process size	Probability	Func Analog Org
oxoacid metabolic process	GO:0043436	103	0.066
organonitrogen compound metabolic process	GO:1901564	318	0.064
vesicle mediated transport	GO:0016192	381	0.053
ion transmembrane transport	GO:0034220	122	0.052	Fly
cellular macromolecule localization	GO:0070727	220	0.051
immune system process	GO:0002376	347	0.050
positive regulation of cell communication	GO:0010647	250	0.049
regulation of transport	GO:0051049	181	0.048
endocytosis	GO:0006897	310	0.046
organic acid metabolic process	GO:0006082	103	0.045
protein complex biogenesis	GO:0070271	201	0.043
protein localization	GO:0008104	284	0.043
positive regulation of signaling	GO:0023056	243	0.040
carboxylic acid metabolic process	GO:0019752	92	0.040
apoptotic process	GO:0006915	159	0.038
regulation of localization	GO:0032879	275	0.038
death	GO:0016265	284	0.036
positive regulation of response to stimulus	GO:0048584	323	0.035
transmembrane transport	GO:0055085	139	0.035	Fly
positive regulation of signal transduction	GO:0009967	223	0.034
actin filament based process	GO:0030029	220	0.033
compound eye development	GO:0048749	307	0.033
macromolecular complex assembly	GO:0065003	256	0.033
protein acylation	GO:0043543	42	0.033
cellular lipid metabolic process	GO:0044255	83	0.033
tissue morphogenesis	GO:0048729	297	0.033
intracellular transport	GO:0046907	228	0.032
kidney development	GO:0001822	3	0.032
single organism intracellular transport	GO:1902582	207	0.031
ion transport	GO:0006811	145	0.031	Fly
organic substance catabolic process	GO:1901575	308	0.031
metal ion transport	GO:0030001	74	0.030	Fly
cellular amino acid metabolic process	GO:0006520	61	0.030
organic substance transport	GO:0071702	257	0.030
neurological system process	GO:0050877	358	0.029
programmed cell death	GO:0012501	257	0.029
establishment of localization in cell	GO:0051649	402	0.029
cellular protein localization	GO:0034613	160	0.028
single organism behavior	GO:0044708	391	0.027
anion homeostasis	GO:0055081	3	0.027
cell death	GO:0008219	279	0.027
regulation of multicellular organismal development	GO:2000026	414	0.027
morphogenesis of an epithelium	GO:0002009	276	0.026
inorganic ion transmembrane transport	GO:0098660	73	0.026	Fly
catabolic process	GO:0009056	409	0.026
imaginal disc derived wing morphogenesis	GO:0007476	337	0.026
phagocytosis	GO:0006909	215	0.026
response to oxygen containing compound	GO:1901700	200	0.026
wing disc morphogenesis	GO:0007472	344	0.026
developmental growth	GO:0048589	280	0.026
response to organic substance	GO:0010033	284	0.025
anion transport	GO:0006820	41	0.025	Fly
connective tissue development	GO:0061448	3	0.025
salivary gland morphogenesis	GO:0007435	145	0.025
positive regulation of transport	GO:0051050	92	0.025
cation transport	GO:0006812	110	0.024	Fly
regulation of cell death	GO:0010941	173	0.024
single organism biosynthetic process	GO:0044711	206	0.024
regulation of growth	GO:0040008	233	0.024
response to nutrient levels	GO:0031667	114	0.023
gland development	GO:0048732	191	0.023
regulation of protein metabolic process	GO:0051246	256	0.022
protein complex assembly	GO:0006461	200	0.022
cytoplasmic transport	GO:0016482	130	0.022
epithelial cell development	GO:0002064	274	0.022
regulation of intracellular signal transduction	GO:1902531	236	0.022
forebrain development	GO:0030900	2	0.022
actin cytoskeleton organization	GO:0030036	206	0.022
regulation of vesicle mediated transport	GO:0060627	59	0.021
protein transport	GO:0015031	155	0.021
salivary gland development	GO:0007431	162	0.021
autophagy	GO:0006914	108	0.021
cellular response to chemical stimulus	GO:0070887	199	0.021
growth	GO:0040007	359	0.021
regulation of cellular component biogenesis	GO:0044087	201	0.021
intracellular signal transduction	GO:0035556	300	0.020
cellular catabolic process	GO:0044248	372	0.020
intracellular protein transport	GO:0006886	104	0.020
actin filament organization	GO:0007015	126	0.020
cellular response to monosaccharide stimulus	GO:0071326	2	0.020
response to other organism	GO:0051707	293	0.020
secretion	GO:0046903	109	0.020
phosphorylation	GO:0016310	294	0.020
small molecule metabolic process	GO:0044281	305	0.020
response to glucose	GO:0009749	2	0.020
cell proliferation	GO:0008283	299	0.020
regionalization	GO:0003002	416	0.019
cell division	GO:0051301	248	0.019
lipid metabolic process	GO:0006629	121	0.019
regulation of cellular ketone metabolic process	GO:0010565	3	0.019
positive regulation of developmental process	GO:0051094	143	0.019
regulation of anatomical structure size	GO:0090066	163	0.019
localization of cell	GO:0051674	257	0.019
epithelial cell differentiation	GO:0030855	322	0.019
eye development	GO:0001654	323	0.019
protein modification process	GO:0036211	438	0.019
regulation of cellular localization	GO:0060341	136	0.019
notch signaling pathway	GO:0007219	120	0.019
regulation of developmental growth	GO:0048638	174	0.018
cell projection assembly	GO:0030031	94	0.018
organonitrogen compound biosynthetic process	GO:1901566	117	0.018
telencephalon development	GO:0021537	2	0.018
ameboidal type cell migration	GO:0001667	151	0.018
compound eye morphogenesis	GO:0001745	249	0.018
regulation of cellular amine metabolic process	GO:0033238	3	0.018
tissue migration	GO:0090130	155	0.018
cell recognition	GO:0008037	102	0.018
organonitrogen compound catabolic process	GO:1901565	128	0.018
single organism cellular localization	GO:1902580	180	0.018
cellular amine metabolic process	GO:0044106	12	0.018
cellular ketone metabolic process	GO:0042180	24	0.018
embryonic morphogenesis	GO:0048598	206	0.018
gland morphogenesis	GO:0022612	145	0.018
negative regulation of signal transduction	GO:0009968	206	0.018
regulation of notch signaling pathway	GO:0008593	100	0.017
carbohydrate derivative biosynthetic process	GO:1901137	85	0.017
cellular component assembly involved in morphogenesis	GO:0010927	151	0.017
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.017
ovarian follicle cell development	GO:0030707	248	0.017
positive regulation of multicellular organismal process	GO:0051240	143	0.017
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.017
regulation of programmed cell death	GO:0043067	152	0.017
carbohydrate derivative metabolic process	GO:1901135	217	0.016
negative regulation of signaling	GO:0023057	219	0.016
developmental maturation	GO:0021700	172	0.016
positive regulation of macromolecule metabolic process	GO:0010604	405	0.016
imaginal disc derived appendage development	GO:0048737	399	0.016
cellular protein modification process	GO:0006464	438	0.016
appendage development	GO:0048736	401	0.016
androgen metabolic process	GO:0008209	1	0.016
sensory organ morphogenesis	GO:0090596	260	0.016
regulation of apoptotic process	GO:0042981	130	0.016
post embryonic appendage morphogenesis	GO:0035120	385	0.016
sulfur compound metabolic process	GO:0006790	59	0.016
response to starvation	GO:0042594	97	0.016
amine metabolic process	GO:0009308	12	0.015
cellular response to hexose stimulus	GO:0071331	1	0.015
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.015
regulation of anatomical structure morphogenesis	GO:0022603	242	0.015
response to monosaccharide	GO:0034284	4	0.015
response to external biotic stimulus	GO:0043207	293	0.015
eye morphogenesis	GO:0048592	260	0.015
regulation of phosphorus metabolic process	GO:0051174	210	0.015
response to endogenous stimulus	GO:0009719	119	0.015
homeostatic process	GO:0042592	199	0.015
nephron development	GO:0072006	3	0.015
positive regulation of cellular component organization	GO:0051130	156	0.015
body morphogenesis	GO:0010171	2	0.015
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.015
response to hexose	GO:0009746	3	0.015
neuron recognition	GO:0008038	101	0.015
negative regulation of notch signaling pathway	GO:0045746	41	0.015
regulation of molecular function	GO:0065009	217	0.015
positive regulation of transcription dna templated	GO:0045893	266	0.015
guanosine containing compound metabolic process	GO:1901068	74	0.015
negative regulation of gene expression	GO:0010629	387	0.014
eye photoreceptor cell differentiation	GO:0001754	145	0.014
chaeta development	GO:0022416	97	0.014
insecticide catabolic process	GO:0046701	1	0.014
cellular amide metabolic process	GO:0043603	80	0.014
ras protein signal transduction	GO:0007265	88	0.014
response to lipopolysaccharide	GO:0032496	4	0.014
golgi organization	GO:0007030	66	0.014
segmentation	GO:0035282	207	0.014
cognition	GO:0050890	141	0.014
positive regulation of intracellular signal transduction	GO:1902533	116	0.014
organophosphate metabolic process	GO:0019637	195	0.014
positive regulation of cell migration	GO:0030335	2	0.014
lateral inhibition	GO:0046331	206	0.014
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.014
fat soluble vitamin metabolic process	GO:0006775	1	0.014
sodium dependent phosphate transport	GO:0044341	2	0.013
regulation of phosphate metabolic process	GO:0019220	210	0.013
phosphate ion transport	GO:0006817	4	0.013
compound eye photoreceptor cell differentiation	GO:0001751	140	0.013
small molecule biosynthetic process	GO:0044283	37	0.013
endomembrane system organization	GO:0010256	119	0.013
secretion by cell	GO:0032940	101	0.013
protein localization to organelle	GO:0033365	82	0.013
response to organonitrogen compound	GO:0010243	75	0.013
exocrine system development	GO:0035272	162	0.013
regulation of cellular amino acid metabolic process	GO:0006521	0	0.013
positive regulation of cell motility	GO:2000147	3	0.013
protein phosphorylation	GO:0006468	169	0.013
regulation of ion transport	GO:0043269	39	0.013
myotube cell development	GO:0014904	3	0.013
cell migration	GO:0016477	238	0.013
l amino acid import	GO:0043092	2	0.013
cellular response to starvation	GO:0009267	61	0.013
anterior posterior axis specification	GO:0009948	109	0.013
glycosyl compound metabolic process	GO:1901657	127	0.012
positive regulation of rna biosynthetic process	GO:1902680	266	0.012
positive regulation of exocytosis	GO:0045921	4	0.012
regulation of cellular component size	GO:0032535	98	0.012
epithelium migration	GO:0090132	148	0.012
l glutamate import	GO:0051938	1	0.012
regulation of organelle organization	GO:0033043	196	0.012
synaptic transmission	GO:0007268	288	0.012
dendrite morphogenesis	GO:0048813	199	0.012
single organism catabolic process	GO:0044712	228	0.012
polyol biosynthetic process	GO:0046173	3	0.012
positive regulation of biosynthetic process	GO:0009891	316	0.012
cellular macromolecular complex assembly	GO:0034622	153	0.012
response to organophosphorus	GO:0046683	2	0.012
response to hormone	GO:0009725	45	0.012
camera type eye development	GO:0043010	4	0.012
epithelial cell migration	GO:0010631	148	0.012
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.012
establishment of protein localization	GO:0045184	163	0.012
monocarboxylic acid transport	GO:0015718	3	0.012
neuromuscular synaptic transmission	GO:0007274	67	0.012
response to organic cyclic compound	GO:0014070	89	0.012
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.012
regulation of catabolic process	GO:0009894	170	0.012
mesenchymal cell differentiation	GO:0048762	1	0.012
positive regulation of secretion	GO:0051047	22	0.011
cellular response to organic substance	GO:0071310	132	0.011
chemosensory behavior	GO:0007635	106	0.011
photoreceptor cell differentiation	GO:0046530	170	0.011
axis specification	GO:0009798	167	0.011
embryonic development via the syncytial blastoderm	GO:0001700	148	0.011
cell adhesion	GO:0007155	136	0.011
regulation of cellular protein metabolic process	GO:0032268	243	0.011
reproductive system development	GO:0061458	74	0.011
neuron fate commitment	GO:0048663	50	0.011
positive regulation of gene expression	GO:0010628	290	0.011
anion transmembrane transport	GO:0098656	26	0.011	Fly
glycoprotein biosynthetic process	GO:0009101	41	0.011
salivary gland histolysis	GO:0035070	88	0.011
defense response	GO:0006952	300	0.011
taxis	GO:0042330	304	0.011
vitamin biosynthetic process	GO:0009110	1	0.011
glycoprotein metabolic process	GO:0009100	41	0.011
purine containing compound metabolic process	GO:0072521	155	0.011
response to nitrogen compound	GO:1901698	90	0.011
positive regulation of phosphorus metabolic process	GO:0010562	139	0.011
jnk cascade	GO:0007254	50	0.011
regulation of actin cytoskeleton organization	GO:0032956	42	0.011
small gtpase mediated signal transduction	GO:0007264	88	0.011
peptidyl amino acid modification	GO:0018193	105	0.011
vacuolar transport	GO:0007034	13	0.011
lipid biosynthetic process	GO:0008610	46	0.011
regulation of response to stress	GO:0080134	200	0.011
histone modification	GO:0016570	106	0.011
kidney epithelium development	GO:0072073	3	0.011
cilium organization	GO:0044782	41	0.011
regulation of synapse assembly	GO:0051963	94	0.011
cellular response to carbohydrate stimulus	GO:0071322	4	0.011
cilium morphogenesis	GO:0060271	39	0.011
positive regulation of catalytic activity	GO:0043085	118	0.011
morphogenesis of embryonic epithelium	GO:0016331	94	0.011
nephron epithelium development	GO:0072009	3	0.011
respiratory system development	GO:0060541	213	0.011
posttranscriptional regulation of gene expression	GO:0010608	145	0.011
developmental growth involved in morphogenesis	GO:0060560	65	0.011
regulation of cell projection organization	GO:0031344	92	0.011
xenobiotic catabolic process	GO:0042178	1	0.011
defense response to bacterium	GO:0042742	178	0.011
cilium assembly	GO:0042384	38	0.011
acid secretion	GO:0046717	1	0.011
lysosomal transport	GO:0007041	13	0.011
anterior posterior pattern specification	GO:0009952	136	0.011
cellular response to oxygen containing compound	GO:1901701	79	0.010
chromosome organization	GO:0051276	360	0.010
post golgi vesicle mediated transport	GO:0006892	11	0.010
cholesterol homeostasis	GO:0042632	3	0.010
regulation of secretion	GO:0051046	44	0.010
organic hydroxy compound metabolic process	GO:1901615	83	0.010
carbohydrate metabolic process	GO:0005975	82	0.010
positive regulation of cellular amine metabolic process	GO:0033240	0	0.010
response to bacterium	GO:0009617	198	0.010
steroid catabolic process	GO:0006706	1	0.010
cellular homeostasis	GO:0019725	80	0.010
male gamete generation	GO:0048232	201	0.010
gtp catabolic process	GO:0006184	72	0.010
negative regulation of response to stimulus	GO:0048585	258	0.010
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.010
heparan sulfate proteoglycan biosynthetic process	GO:0015012	10	0.010
amino sugar catabolic process	GO:0046348	3	0.010
hindbrain development	GO:0030902	2	0.010
appendage morphogenesis	GO:0035107	397	0.010
organic cyclic compound catabolic process	GO:1901361	168	0.010
ribose phosphate metabolic process	GO:0019693	145	0.010
negative regulation of growth	GO:0045926	84	0.010
negative regulation of multicellular organismal process	GO:0051241	142	0.010
response to mercury ion	GO:0046689	3	0.010
anterior posterior axis specification embryo	GO:0008595	103	0.010
open tracheal system development	GO:0007424	204	0.010
photoreceptor cell fate commitment	GO:0046552	41	0.010
glycerolipid metabolic process	GO:0046486	34	0.010

CG12773 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.052
nervous system disease	DOID:863	0.018
urinary system disease	DOID:18	0.015
disease of metabolism	DOID:0014667	0.013
cardiovascular system disease	DOID:1287	0.013
central nervous system disease	DOID:331	0.013
musculoskeletal system disease	DOID:17	0.012
inherited metabolic disorder	DOID:655	0.011
kidney disease	DOID:557	0.010
sensory system disease	DOID:0050155	0.010
disease of cellular proliferation	DOID:14566	0.010

Loading network...

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network