Drosophila melanogaster

13 known processes

Pros45 (Dmel_CG1489)

CG1489 gene product from transcript CG1489-RA

(Aliases: Rpt6,p42C,PRS8_DROME,Ug,Dm_Rpt6a,dRpt6,Dug,Dmel\CG1489,pros45,sug-1,1489,DUG,sug1,CG1489)

Pros45 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
proteasome assemblyGO:004324820.659
Yeast
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.657
Yeast
regulation of transcription from rna polymerase ii promoterGO:00063573780.600
Yeast
protein complex biogenesisGO:00702712010.583
Yeast
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434370.491
proteolysisGO:00065081920.481
cellular protein complex assemblyGO:0043623710.452
Yeast
modification dependent macromolecule catabolic processGO:0043632790.447
Human Yeast Worm
positive regulation of cellular biosynthetic processGO:00313283160.376
Yeast
positive regulation of nitrogen compound metabolic processGO:00511733540.360
Yeast
modification dependent protein catabolic processGO:0019941780.346
Human Yeast Worm
transcription from rna polymerase ii promoterGO:00063663680.339
Yeast
protein complex assemblyGO:00064612000.332
Yeast
transcription initiation from rna polymerase ii promoterGO:0006367250.327
Yeast
macromolecular complex assemblyGO:00650032560.325
Yeast
mitotic spindle elongationGO:0000022810.304
proteasomal protein catabolic processGO:0010498590.298
Human Yeast Worm
positive regulation of transcription dna templatedGO:00458932660.266
Yeast
dna templated transcription initiationGO:0006352250.255
Yeast
spindle assemblyGO:0051225800.254
regulation of cellular component biogenesisGO:00440872010.254
Yeast Rat
positive regulation of rna metabolic processGO:00512542710.248
Yeast
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.239
Human Yeast Worm
embryo development ending in birth or egg hatchingGO:00097921520.232
Worm
positive regulation of nucleobase containing compound metabolic processGO:00459353320.230
Yeast
positive regulation of rna biosynthetic processGO:19026802660.227
Yeast
cellular macromolecular complex assemblyGO:00346221530.220
Yeast
catabolic processGO:00090564090.212
Human Yeast Rat Worm
positive regulation of nucleic acid templated transcriptionGO:19035082660.197
Yeast
positive regulation of macromolecule biosynthetic processGO:00105572830.196
Yeast
cellular response to dna damage stimulusGO:00069742230.195
rna polymerase ii transcriptional preinitiation complex assemblyGO:0051123200.190
Yeast
cellular macromolecule catabolic processGO:00442651360.157
Human Yeast Worm
spindle elongationGO:0051231830.153
cellular catabolic processGO:00442483720.144
Human Yeast Rat Worm
negative regulation of cell communicationGO:00106482230.140
nuclear divisionGO:00002803320.140
Worm
positive regulation of proteolysisGO:0045862520.133
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.130
mitotic spindle organizationGO:00070522200.125
negative regulation of cellular biosynthetic processGO:00313272770.124
Mouse
spindle organizationGO:00070512530.122
cellular protein catabolic processGO:0044257830.118
Human Yeast Worm
centrosome organizationGO:00512971630.116
proteolysis involved in cellular protein catabolic processGO:0051603830.115
Human Yeast Worm
body morphogenesisGO:001017120.109
positive regulation of proteasomal protein catabolic processGO:1901800200.101
lateral inhibitionGO:00463312060.100
organic substance catabolic processGO:19015753080.100
Human Yeast Rat Worm
protein catabolic processGO:00301631010.099
Human Yeast Worm
ubiquitin dependent protein catabolic processGO:0006511780.094
Human Yeast Worm
regulation of macroautophagyGO:0016241150.090
regulation of behaviorGO:0050795750.087
dna templated transcriptional preinitiation complex assemblyGO:0070897200.082
Yeast
organelle fissionGO:00482853400.080
Worm
regulation of proteasomal protein catabolic processGO:0061136390.080
positive regulation of peptidase activityGO:0010952290.078
multicellular organismal agingGO:00102591400.076
Worm
protein localizationGO:00081042840.075
positive regulation of biosynthetic processGO:00098913160.075
Yeast
positive regulation of cellular component organizationGO:00511301560.074
Yeast Rat
negative regulation of biosynthetic processGO:00098902770.072
Mouse
ion transmembrane transportGO:00342201220.070
deathGO:00162652840.067
negative regulation of gene expressionGO:00106293870.065
Mouse
positive regulation of cellular component biogenesisGO:0044089800.065
Yeast Rat
microtubule cytoskeleton organization involved in mitosisGO:1902850520.059
determination of adult lifespanGO:00083401370.057
Worm
gland developmentGO:00487321910.057
macromolecule catabolic processGO:00090571610.055
Human Yeast Worm
cell deathGO:00082192790.052
positive regulation of gene expressionGO:00106282900.052
Yeast
regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:004589810.052
Yeast
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052240.052
organonitrogen compound metabolic processGO:19015643180.051
Rat
regulation of mitotic cell cycleGO:00073461900.051
Worm
regulation of organelle organizationGO:00330431960.051
Worm
learningGO:0007612750.050
negative regulation of macromolecule biosynthetic processGO:00105582700.047
Mouse
microtubule organizing center organizationGO:00310231680.047
mitotic nuclear divisionGO:00070672130.046
Worm
negative regulation of cellular metabolic processGO:00313243820.046
Mouse
cellular protein modification processGO:00064644380.046
regulation of cellular protein metabolic processGO:00322682430.045
regulation of endopeptidase activityGO:0052548360.044
regulation of cellular ketone metabolic processGO:001056530.043
negative regulation of nitrogen compound metabolic processGO:00511722650.043
Mouse
organelle assemblyGO:00709251980.042
protein modification processGO:00362114380.041
agingGO:00075681430.040
Worm
neurological system processGO:00508773580.038
negative regulation of signal transductionGO:00099682060.038
apoptotic processGO:00069151590.038
response to nutrient levelsGO:00316671140.038
forebrain developmentGO:003090020.038
positive regulation of endopeptidase activityGO:0010950260.038
metal ion transportGO:0030001740.037
regulation of proteolysisGO:0030162870.037
regulation of protein complex assemblyGO:0043254420.037
Yeast
phagocytosisGO:00069092150.036
positive regulation of cell communicationGO:00106472500.035
negative regulation of cellular protein metabolic processGO:0032269850.035
regulation of cell developmentGO:00602842150.034
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.034
Mouse
regulation of peptidase activityGO:0052547390.034
spindle assembly involved in mitosisGO:0090307500.033
negative regulation of transcription dna templatedGO:00458922370.033
Mouse
cellular response to chemical stimulusGO:00708871990.032
purine containing compound metabolic processGO:00725211550.032
Rat
positive regulation of macromolecule metabolic processGO:00106044050.032
Yeast
taxisGO:00423303040.032
aromatic compound catabolic processGO:00194391660.032
Yeast Rat
positive regulation of protein complex assemblyGO:0031334220.031
Yeast
sensory perceptionGO:00076001960.031
single organism behaviorGO:00447083910.030
regulation of cellular protein catabolic processGO:1903362440.030
nucleoside catabolic processGO:00091641120.030
Rat
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436190.030
cellular homeostasisGO:0019725800.030
regulation of response to stressGO:00801342000.030
purine ribonucleotide metabolic processGO:00091501450.029
Rat
rna processingGO:00063961470.029
chemotaxisGO:00069352490.029
purine ribonucleoside metabolic processGO:00461281270.028
Rat
negative regulation of protein metabolic processGO:0051248850.028
regulation of protein catabolic processGO:0042176550.028
cellular macromolecule localizationGO:00707272200.028
regulation of cellular catabolic processGO:00313291570.028
purine nucleoside catabolic processGO:00061521120.028
Rat
response to organic substanceGO:00100332840.028
nucleoside monophosphate metabolic processGO:0009123520.028
Rat
larval developmentGO:00021641040.027
Worm
intracellular signal transductionGO:00355563000.027
limb developmentGO:006017310.027
carbohydrate derivative metabolic processGO:19011352170.027
Rat
nucleobase containing compound catabolic processGO:00346551650.026
Yeast Rat
multicellular organismal reproductive behaviorGO:00330571100.026
regulation of cell cycle processGO:00105641810.026
Worm
cation transportGO:00068121100.025
meiotic cell cycleGO:00513211710.025
chromosome segregationGO:00070591570.025
Worm
negative regulation of response to stimulusGO:00485852580.025
regulation of response to external stimulusGO:00321011150.025
regulation of catalytic activityGO:00507901850.025
ion transportGO:00068111450.024
dna metabolic processGO:00062592270.024
Yeast
regulation of cell projection organizationGO:0031344920.024
cell cell signaling involved in cell fate commitmentGO:00451682100.024
positive regulation of cellular protein metabolic processGO:00322701180.023
regulation of gene expression epigeneticGO:00400291280.023
negative regulation of signalingGO:00230572190.023
positive regulation of cellular catabolic processGO:0031331950.023
cellular component assembly involved in morphogenesisGO:00109271510.023
cognitionGO:00508901410.022
exocrine system developmentGO:00352721620.022
establishment of protein localizationGO:00451841630.022
regulation of cell cycleGO:00517262910.021
Worm
heterocycle catabolic processGO:00467001660.021
Yeast Rat
positive regulation of response to stimulusGO:00485843230.021
positive regulation of intracellular signal transductionGO:19025331160.021
regulation of multicellular organismal developmentGO:20000264140.021
response to oxidative stressGO:0006979860.021
associative learningGO:0008306650.021
nucleoside phosphate catabolic processGO:19012921100.021
Rat
microtubule polymerization or depolymerizationGO:0031109390.020
establishment of localization in cellGO:00516494020.020
mrna processingGO:00063971040.020
er associated ubiquitin dependent protein catabolic processGO:003043330.019
regulation of molecular functionGO:00650092170.019
Yeast
positive regulation of catabolic processGO:00098961050.019
protein transportGO:00150311550.019
regulation of catabolic processGO:00098941700.019
protein deubiquitinationGO:0016579170.018
organic substance transportGO:00717022570.018
positive regulation of signalingGO:00230562430.018
cellular chemical homeostasisGO:0055082400.018
response to light stimulusGO:00094161240.018
ribonucleoside triphosphate metabolic processGO:00091991190.018
Rat
positive regulation of molecular functionGO:00440931360.018
Yeast
vesicle mediated transportGO:00161923810.018
regulation of intracellular signal transductionGO:19025312360.018
gene silencingGO:00164581380.017
nucleoside phosphate metabolic processGO:00067531620.017
Rat
regulation of cell differentiationGO:00455953020.017
negative regulation of cell developmentGO:0010721620.017
divalent inorganic cation transportGO:0072511300.017
endomembrane system organizationGO:00102561190.017
regulation of mitosisGO:0007088560.016
Worm
regulation of cellular response to stressGO:0080135890.016
regulation of dna templated transcription elongationGO:0032784170.016
Yeast
protein phosphorylationGO:00064681690.016
response to radiationGO:00093141550.016
transcription elongation from rna polymerase ii promoterGO:0006368180.016
Yeast
mrna cis splicing via spliceosomeGO:004529210.016
negative regulation of cellular catabolic processGO:0031330340.016
reproductive structure developmentGO:0048608740.016
Worm
negative regulation of proteasomal protein catabolic processGO:1901799160.016
cellular cation homeostasisGO:0030003380.016
camera type eye developmentGO:004301040.015
regulation of protein modification processGO:00313991120.015
mitotic cell cycle phase transitionGO:00447721380.015
Worm
ribonucleotide catabolic processGO:00092611090.015
Rat
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092380.015
nucleoside triphosphate catabolic processGO:00091431080.015
Rat
regulation of cell divisionGO:0051302720.015
Worm
regulation of cellular amine metabolic processGO:003323830.015
peptide biosynthetic processGO:0043043420.015
nucleus localizationGO:0051647340.015
posttranscriptional gene silencing by rnaGO:0035194450.015
regulation of protein transportGO:0051223570.015
transmembrane transportGO:00550851390.015
purine nucleoside monophosphate catabolic processGO:0009128380.015
Rat
programmed cell deathGO:00125012570.014
response to other organismGO:00517072930.014
regulation of multi organism processGO:00439001310.014
homeostatic processGO:00425921990.014
single organism catabolic processGO:00447122280.014
Rat Worm
carbohydrate derivative catabolic processGO:19011361180.014
Rat
nucleobase containing small molecule metabolic processGO:00550861740.014
Rat
single organism cellular localizationGO:19025801800.014
positive regulation of signal transductionGO:00099672230.014
negative regulation of cell cycleGO:00457861160.014
cell proliferationGO:00082832990.013
regulation of gene silencingGO:0060968630.013
positive regulation of protein catabolic processGO:0045732340.013
protein localization to organelleGO:0033365820.013
learning or memoryGO:00076111410.013
rna interferenceGO:0016246270.013
negative regulation of cellular component organizationGO:00511291080.013
regulation of phosphate metabolic processGO:00192202100.012
regulation of hydrolase activityGO:0051336970.012
regulation of synapse assemblyGO:0051963940.012
protein dna complex subunit organizationGO:0071824860.012
Yeast
ribose phosphate metabolic processGO:00196931450.012
Rat
response to biotic stimulusGO:00096072940.012
organonitrogen compound catabolic processGO:19015651280.012
Rat
protein ubiquitinationGO:0016567700.012
endocytosisGO:00068973100.012
regulation of locomotionGO:0040012420.012
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377730.012
purine ribonucleoside triphosphate metabolic processGO:00092051190.012
Rat
nucleotide catabolic processGO:00091661090.012
Rat
organophosphate catabolic processGO:00464341120.012
Rat
response to oxygen containing compoundGO:19017002000.012
purine nucleoside triphosphate metabolic processGO:00091441190.012
Rat
amine metabolic processGO:0009308120.012
ribonucleoside monophosphate catabolic processGO:0009158390.012
Rat
salivary gland morphogenesisGO:00074351450.011
molting cycleGO:0042303560.011
regulation of microtubule based processGO:0032886490.011
telencephalon developmentGO:002153720.011
response to organonitrogen compoundGO:0010243750.011
amide biosynthetic processGO:0043604420.011
nucleoside metabolic processGO:00091161270.011
Rat
cytoplasmic transportGO:00164821300.011
development of primary sexual characteristicsGO:0045137500.011
Worm
meiotic nuclear divisionGO:00071261510.011
cellular amine metabolic processGO:0044106120.011
regulation of epithelial cell proliferationGO:005067840.010
response to endogenous stimulusGO:00097191190.010
protein polymerizationGO:0051258420.010
positive regulation of phosphate metabolic processGO:00459371390.010
regulation of innate immune responseGO:0045088710.010
organonitrogen compound biosynthetic processGO:19015661170.010
regulation of immune system processGO:00026821760.010

Pros45 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.029
nervous system diseaseDOID:86300.015