Drosophila melanogaster

39 known processes

bnk (Dmel_CG1480)

bottleneck

(Aliases: Bnk,Dmel\CG1480,CG1480)

bnk biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
detection of stimulus involved in sensory perceptionGO:0050906920.304
detection of chemical stimulus involved in sensory perceptionGO:0050907750.214
detection of stimulusGO:00516061560.198
detection of chemical stimulusGO:0009593930.195
detection of chemical stimulus involved in sensory perception of smellGO:0050911500.175
sensory perceptionGO:00076001960.139
neurological system processGO:00508773580.134
sensory perception of chemical stimulusGO:00076061160.117
lateral inhibitionGO:00463312060.092
protein hydroxylationGO:001812610.068
peptidyl proline hydroxylationGO:001951110.064
sensory perception of smellGO:0007608800.064
gland developmentGO:00487321910.057
cell cell signaling involved in cell fate commitmentGO:00451682100.056
salivary gland developmentGO:00074311620.054
cellular protein modification processGO:00064644380.052
salivary gland morphogenesisGO:00074351450.050
protein modification processGO:00362114380.050
protein heterooligomerizationGO:005129140.049
positive regulation of nucleobase containing compound metabolic processGO:00459353320.043
macromolecular complex assemblyGO:00650032560.042
body morphogenesisGO:001017120.041
gland morphogenesisGO:00226121450.041
exocrine system developmentGO:00352721620.037
peptidyl proline modificationGO:001820830.036
single organism behaviorGO:00447083910.035
response to abiotic stimulusGO:00096283410.035
positive regulation of biosynthetic processGO:00098913160.034
positive regulation of nitrogen compound metabolic processGO:00511733540.033
single organism cellular localizationGO:19025801800.032
establishment of localization in cellGO:00516494020.032
response to lipopolysaccharideGO:003249640.031
positive regulation of macromolecule metabolic processGO:00106044050.030
tissue morphogenesisGO:00487292970.030
organonitrogen compound metabolic processGO:19015643180.029
protein complex assemblyGO:00064612000.028
negative regulation of response to stimulusGO:00485852580.028
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.028
positive regulation of transcription dna templatedGO:00458932660.028
regionalizationGO:00030024160.027
positive regulation of rna metabolic processGO:00512542710.027
epithelial cell differentiationGO:00308553220.027
protein complex biogenesisGO:00702712010.027
response to external biotic stimulusGO:00432072930.026
organic substance transportGO:00717022570.026
small molecule metabolic processGO:00442813050.026
positive regulation of cellular biosynthetic processGO:00313283160.026
transcription from rna polymerase ii promoterGO:00063663680.026
negative regulation of cellular metabolic processGO:00313243820.026
positive regulation of rna biosynthetic processGO:19026802660.026
regulation of cell differentiationGO:00455953020.025
peptidyl amino acid modificationGO:00181931050.025
negative regulation of gene expressionGO:00106293870.025
locomotory behaviorGO:00076261760.024
growthGO:00400073590.024
forebrain developmentGO:003090020.024
intracellular transportGO:00469072280.024
imaginal disc derived wing morphogenesisGO:00074763370.024
cytoskeleton dependent intracellular transportGO:0030705440.024
developmental growthGO:00485892800.024
response to biotic stimulusGO:00096072940.024
carboxylic acid metabolic processGO:0019752920.024
regulation of localizationGO:00328792750.024
muscle structure developmentGO:00610612240.024
positive regulation of gene expressionGO:00106282900.024
regulation of phosphate metabolic processGO:00192202100.023
deathGO:00162652840.023
compound eye developmentGO:00487493070.023
regulation of developmental growthGO:00486381740.023
vesicle mediated transportGO:00161923810.023
organelle localizationGO:00516401480.023
regulation of cell developmentGO:00602842150.023
positive regulation of nucleic acid templated transcriptionGO:19035082660.023
tube developmentGO:00352952440.022
tube morphogenesisGO:00352391910.022
wing disc morphogenesisGO:00074723440.022
eye developmentGO:00016543230.022
embryonic development via the syncytial blastodermGO:00017001480.022
immune responseGO:00069552460.022
response to other organismGO:00517072930.022
immune system processGO:00023763470.022
positive regulation of response to stimulusGO:00485843230.021
oxoacid metabolic processGO:00434361030.021
post embryonic appendage morphogenesisGO:00351203850.021
mating behaviorGO:00076171060.021
regulation of growthGO:00400082330.021
phosphorylationGO:00163102940.021
morphogenesis of an epitheliumGO:00020092760.021
negative regulation of macromolecule biosynthetic processGO:00105582700.021
single organism biosynthetic processGO:00447112060.021
sensory organ morphogenesisGO:00905962600.021
defense responseGO:00069523000.021
negative regulation of nitrogen compound metabolic processGO:00511722650.020
appendage morphogenesisGO:00351073970.020
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.020
negative regulation of multicellular organismal processGO:00512411420.020
programmed cell deathGO:00125012570.020
single organism intracellular transportGO:19025822070.020
organic substance catabolic processGO:19015753080.020
cellular response to dna damage stimulusGO:00069742230.020
embryonic morphogenesisGO:00485982060.020
cell deathGO:00082192790.020
respiratory system developmentGO:00605412130.020
camera type eye developmentGO:004301040.020
positive regulation of macromolecule biosynthetic processGO:00105572830.020
imaginal disc derived appendage morphogenesisGO:00351143950.020
localization of cellGO:00516742570.020
cell divisionGO:00513012480.019
negative regulation of nucleic acid templated transcriptionGO:19035072400.019
homeostatic processGO:00425921990.019
organic acid metabolic processGO:00060821030.019
eye morphogenesisGO:00485922600.019
appendage developmentGO:00487364010.019
regulation of multicellular organismal developmentGO:20000264140.019
negative regulation of developmental processGO:00510932010.019
catabolic processGO:00090564090.019
response to oxygen containing compoundGO:19017002000.019
carbohydrate derivative metabolic processGO:19011352170.019
innate immune responseGO:00450871440.018
negative regulation of cellular biosynthetic processGO:00313272770.018
regulation of cell cycleGO:00517262910.018
humoral immune responseGO:00069591170.018
developmental programmed cell deathGO:00106231380.018
regulation of phosphorus metabolic processGO:00511742100.018
columnar cuboidal epithelial cell differentiationGO:00020652560.018
anatomical structure homeostasisGO:0060249970.018
microtubule based transportGO:0010970420.018
microtubule based movementGO:0007018510.018
positive regulation of signal transductionGO:00099672230.018
reproductive behaviorGO:00190981220.018
response to nutrient levelsGO:00316671140.018
single organism catabolic processGO:00447122280.018
regulation of cellular ketone metabolic processGO:001056530.018
tissue deathGO:00162711020.018
cellular response to chemical stimulusGO:00708871990.017
actin cytoskeleton organizationGO:00300362060.017
columnar cuboidal epithelial cell developmentGO:00020662490.017
response to organic substanceGO:00100332840.017
hindbrain developmentGO:003090220.017
negative regulation of biosynthetic processGO:00098902770.017
multi organism behaviorGO:00517051750.017
positive regulation of cell communicationGO:00106472500.017
synaptic transmissionGO:00072682880.017
regulation of cell cycle processGO:00105641810.017
amine metabolic processGO:0009308120.017
negative regulation of signalingGO:00230572190.017
steroid catabolic processGO:000670610.017
regulation of response to stressGO:00801342000.017
phagocytosisGO:00069092150.016
cellular catabolic processGO:00442483720.016
imaginal disc derived appendage developmentGO:00487373990.016
matingGO:00076181200.016
positive regulation of cellular component organizationGO:00511301560.016
response to organic cyclic compoundGO:0014070890.016
protein localizationGO:00081042840.016
developmental maturationGO:00217001720.016
cell proliferationGO:00082832990.016
epithelial cell developmentGO:00020642740.016
negative regulation of rna biosynthetic processGO:19026792400.016
response to temperature stimulusGO:00092661060.016
somatic muscle developmentGO:0007525660.016
multi organism reproductive behaviorGO:00447051210.016
response to nitrogen compoundGO:1901698900.016
taxisGO:00423303040.016
nucleobase containing small molecule metabolic processGO:00550861740.016
response to radiationGO:00093141550.016
courtship behaviorGO:0007619680.016
regulation of immune responseGO:00507761180.016
chromosome organizationGO:00512763600.016
compound eye morphogenesisGO:00017452490.016
positive regulation of signalingGO:00230562430.016
cellular amino acid metabolic processGO:0006520610.016
regulation of nervous system developmentGO:00519602480.016
negative regulation of growthGO:0045926840.016
telencephalon developmentGO:002153720.016
ribonucleotide metabolic processGO:00092591450.015
regulation of transcription from rna polymerase ii promoterGO:00063573780.015
regulation of protein metabolic processGO:00512462560.015
dorsal ventral pattern formationGO:00099531330.015
organophosphate metabolic processGO:00196371950.015
detection of external stimulusGO:0009581660.015
muscle organ developmentGO:00075171270.015
negative regulation of cell communicationGO:00106482230.015
regulation of cellular amine metabolic processGO:003323830.015
regulation of molecular functionGO:00650092170.015
organonitrogen compound biosynthetic processGO:19015661170.015
regulation of immune system processGO:00026821760.015
intracellular signal transductionGO:00355563000.015
regulation of gene expression epigeneticGO:00400291280.015
dendrite developmentGO:00163582040.015
gene silencingGO:00164581380.015
regulation of cellular protein metabolic processGO:00322682430.015
response to bacteriumGO:00096171980.015
multicellular organismal reproductive behaviorGO:00330571100.015
embryo development ending in birth or egg hatchingGO:00097921520.015
negative regulation of nucleobase containing compound metabolic processGO:00459342610.015
dendrite morphogenesisGO:00488131990.015
regulation of cellular amino acid metabolic processGO:000652100.015
nuclear divisionGO:00002803320.015
response to monosaccharideGO:003428440.015
response to woundingGO:0009611940.015
negative regulation of rna metabolic processGO:00512532510.015
antimicrobial humoral responseGO:0019730990.015
sensory perception of painGO:001923340.015
spindle organizationGO:00070512530.015
segmentationGO:00352822070.015
regulation of transportGO:00510491810.015
histolysisGO:00075591020.015
endocytosisGO:00068973100.015
actin filament based processGO:00300292200.015
nucleotide metabolic processGO:00091171610.015
nephron developmentGO:007200630.015
regulation of phosphorylationGO:00423251470.014
mitotic nuclear divisionGO:00070672130.014
response to light stimulusGO:00094161240.014
regulation of anatomical structure sizeGO:00900661630.014
negative regulation of transcription dna templatedGO:00458922370.014
regulation of organelle organizationGO:00330431960.014
ion transmembrane transportGO:00342201220.014
axis specificationGO:00097981670.014
negative regulation of signal transductionGO:00099682060.014
response to hexoseGO:000974630.014
cell motilityGO:00488702510.014
organelle fissionGO:00482853400.014
regulation of cell deathGO:00109411730.014
cell migrationGO:00164772380.014
cation transportGO:00068121100.014
digestive system developmentGO:00551231490.014
multi multicellular organism processGO:00447061230.014
blastoderm segmentationGO:00073501590.014
ovarian follicle cell developmentGO:00307072480.014
regulation of multi organism processGO:00439001310.014
digestive tract developmentGO:00485651490.014
anterior posterior pattern specificationGO:00099521360.014
open tracheal system developmentGO:00074242040.014
organelle assemblyGO:00709251980.014
regulation of catalytic activityGO:00507901850.014
regulation of cellular component biogenesisGO:00440872010.014
cellular component assembly involved in morphogenesisGO:00109271510.014
posttranscriptional regulation of gene expressionGO:00106081450.014
chorion containing eggshell formationGO:00073041050.013
salivary gland histolysisGO:0035070880.013
male gamete generationGO:00482322010.013
eggshell formationGO:00307031050.013
regulation of cell morphogenesisGO:00226041630.013
response to endogenous stimulusGO:00097191190.013
regulation of mitotic cell cycleGO:00073461900.013
response to organophosphorusGO:004668320.013
regulation of synapse structure and activityGO:00508031280.013
cellular macromolecule localizationGO:00707272200.013
nucleoside phosphate metabolic processGO:00067531620.013
negative regulation of cell differentiationGO:00455961430.013
positive regulation of molecular functionGO:00440931360.013
response to extracellular stimulusGO:00099911160.013
wound healingGO:0042060750.013
hindgut morphogenesisGO:0007442580.013
regulation of anatomical structure morphogenesisGO:00226032420.013
cellular amine metabolic processGO:0044106120.013
transmembrane transportGO:00550851390.013
autophagic cell deathGO:0048102830.013
retina development in camera type eyeGO:006004140.013
chemosensory behaviorGO:00076351060.013
macromolecule catabolic processGO:00090571610.013
feeding behaviorGO:0007631500.013
male courtship behaviorGO:0008049630.013
cellular response to oxygen containing compoundGO:1901701790.013
central nervous system developmentGO:00074172010.013
chemotaxisGO:00069352490.013
enzyme linked receptor protein signaling pathwayGO:00071671790.013
kidney developmentGO:000182230.013
regulation of notch signaling pathwayGO:00085931000.013
regulation of response to external stimulusGO:00321011150.013
epibolyGO:009050420.012
digestive tract morphogenesisGO:00485461270.012
positive regulation of phosphorus metabolic processGO:00105621390.012
regulation of intracellular signal transductionGO:19025312360.012
behavioral response to painGO:004826630.012
endomembrane system organizationGO:00102561190.012
negative regulation of cell cycle processGO:00109481090.012
camera type eye morphogenesisGO:004859320.012
organ growthGO:0035265560.012
positive regulation of multicellular organismal processGO:00512401430.012
connective tissue developmentGO:006144830.012
negative regulation of developmental growthGO:0048640640.012
photoreceptor cell differentiationGO:00465301700.012
detection of abiotic stimulusGO:0009582660.012
neuron projection guidanceGO:00974852410.012
salivary gland cell autophagic cell deathGO:0035071830.012
ion transportGO:00068111450.012
cell maturationGO:00484691440.012
eye photoreceptor cell differentiationGO:00017541450.012
multicellular organismal agingGO:00102591400.012
cellular protein localizationGO:00346131600.012
cellular ketone metabolic processGO:0042180240.012
purine ribonucleotide metabolic processGO:00091501450.012
defense response to gram negative bacteriumGO:0050829940.012
cell growthGO:00160491080.012
regulation of organ growthGO:0046620420.012
proteolysisGO:00065081920.012
regulation of catabolic processGO:00098941700.012
notch signaling pathwayGO:00072191200.012
chaeta developmentGO:0022416970.012
chromatin silencingGO:0006342760.012
anterior posterior axis specification embryoGO:00085951030.012
positive regulation of phosphate metabolic processGO:00459371390.012
positive regulation of intracellular signal transductionGO:19025331160.012
axonogenesisGO:00074092900.012
embryonic axis specificationGO:00005781070.012
actin filament organizationGO:00070151260.012
purine containing compound metabolic processGO:00725211550.011
rna localizationGO:00064031150.011
establishment of protein localizationGO:00451841630.011
defense response to bacteriumGO:00427421780.011
inorganic ion transmembrane transportGO:0098660730.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.011
chromatin modificationGO:00165681470.011
cellular response to molecule of bacterial originGO:007121930.011
vitamin metabolic processGO:000676620.011
epiboly involved in wound healingGO:009050520.011
response to painGO:004826530.011
secretion by cellGO:00329401010.011
oocyte differentiationGO:00099941450.011
regulation of behaviorGO:0050795750.011
ribose phosphate metabolic processGO:00196931450.011
spermatogenesisGO:00072832000.011
negative regulation of gene expression epigeneticGO:0045814770.011
water homeostasisGO:003010430.011
purine nucleotide metabolic processGO:00061631460.011
aromatic compound catabolic processGO:00194391660.011
chemical homeostasisGO:0048878920.011
dna metabolic processGO:00062592270.011
mitotic spindle organizationGO:00070522200.011
regulation of gene silencingGO:0060968630.011
establishment or maintenance of cell polarityGO:00071631670.011
dna integrity checkpointGO:0031570810.011
regulation of epithelial cell differentiationGO:003085640.011
organic cyclic compound catabolic processGO:19013611680.011
cellular response to organic substanceGO:00713101320.011
spinal cord developmentGO:002151010.011
response to alcoholGO:0097305950.011
regulation of neuron differentiationGO:00456641030.011
benzene containing compound metabolic processGO:004253730.011
mitotic cell cycle checkpointGO:0007093880.011
stem cell differentiationGO:00488631170.011
regulation of cellular component sizeGO:0032535980.010
determination of adult lifespanGO:00083401370.010
chromatin organizationGO:00063252070.010
pigment metabolic processGO:0042440840.010
regulation of response to biotic stimulusGO:0002831630.010
imaginal disc pattern formationGO:0007447910.010
cell cycle phase transitionGO:00447701400.010
cellular homeostasisGO:0019725800.010
sensory perception of mechanical stimulusGO:0050954720.010
embryonic pattern specificationGO:00098801740.010
regulation of defense responseGO:00313471020.010
chromosome segregationGO:00070591570.010
mesenchymal cell differentiationGO:004876210.010
dorsal ventral axis specificationGO:0009950660.010
regulation of mitotic cell cycle phase transitionGO:19019901300.010
cellular macromolecular complex assemblyGO:00346221530.010
hematopoietic progenitor cell differentiationGO:000224410.010
cellular response to biotic stimulusGO:007121640.010
cell adhesionGO:00071551360.010
rhythmic behaviorGO:0007622760.010
response to heatGO:0009408630.010
rna processingGO:00063961470.010
cellular response to lipopolysaccharideGO:007122230.010
head developmentGO:00603221350.010
positive regulation of catalytic activityGO:00430851180.010
heterocycle catabolic processGO:00467001660.010
mesenchymal cell developmentGO:001403110.010
small gtpase mediated signal transductionGO:0007264880.010
positive regulation of cell motilityGO:200014730.010
monocarboxylic acid transportGO:001571830.010

bnk disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.056
disease of metabolismDOID:001466700.027
inherited metabolic disorderDOID:65500.017
urinary system diseaseDOID:1800.016
nervous system diseaseDOID:86300.014
kidney diseaseDOID:55700.014
renal tubular transport diseaseDOID:44700.014
respiratory system diseaseDOID:157900.014
acquired metabolic diseaseDOID:006015800.013
musculoskeletal system diseaseDOID:1700.011
liddle syndromeDOID:005047700.010
cardiovascular system diseaseDOID:128700.010