IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

CG5250 (Dmel_CG5250)

CG5250 gene product from transcript CG5250-RA

(Aliases: Dmel\CG5250)

Entrez: 42308
FLYBASE: FBgn0038691
UniProtKB: Q9VDY7

Process Predictions
Disease Predictions

CG5250 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
protein modification process	GO:0036211	438	0.100
phosphorylation	GO:0016310	294	0.081
cellular protein modification process	GO:0006464	438	0.074
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.040
protein phosphorylation	GO:0006468	169	0.037
small molecule metabolic process	GO:0044281	305	0.034	Human Rat Fly
organonitrogen compound metabolic process	GO:1901564	318	0.033	Human Rat Fly
response to abiotic stimulus	GO:0009628	341	0.033	Rat Fly
oxoacid metabolic process	GO:0043436	103	0.032
regulation of molecular function	GO:0065009	217	0.030	Human
organic acid metabolic process	GO:0006082	103	0.030
carbohydrate derivative metabolic process	GO:1901135	217	0.030	Human Rat Fly
carboxylic acid metabolic process	GO:0019752	92	0.029
neurological system process	GO:0050877	358	0.029	Fly
immune system process	GO:0002376	347	0.029
organic substance transport	GO:0071702	257	0.028
wing disc morphogenesis	GO:0007472	344	0.028
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.027
appendage morphogenesis	GO:0035107	397	0.027
vesicle mediated transport	GO:0016192	381	0.027
imaginal disc derived wing morphogenesis	GO:0007476	337	0.027
appendage development	GO:0048736	401	0.026
cellular macromolecule localization	GO:0070727	220	0.026
regulation of cellular protein metabolic process	GO:0032268	243	0.026
protein localization	GO:0008104	284	0.025
regulation of catalytic activity	GO:0050790	185	0.025	Human
imaginal disc derived appendage development	GO:0048737	399	0.025
organophosphate metabolic process	GO:0019637	195	0.025	Human Rat Fly
positive regulation of response to stimulus	GO:0048584	323	0.025
single organism cellular localization	GO:1902580	180	0.025
regulation of cellular component biogenesis	GO:0044087	201	0.024
cytoplasmic transport	GO:0016482	130	0.024
organic substance catabolic process	GO:1901575	308	0.024	Human Rat Fly
endocytosis	GO:0006897	310	0.024
regulation of phosphorylation	GO:0042325	147	0.024
intracellular signal transduction	GO:0035556	300	0.024
post embryonic appendage morphogenesis	GO:0035120	385	0.023
sensory organ morphogenesis	GO:0090596	260	0.023
spermatid development	GO:0007286	98	0.022
establishment of localization in cell	GO:0051649	402	0.022
intracellular protein transport	GO:0006886	104	0.022
positive regulation of cell communication	GO:0010647	250	0.022
phagocytosis	GO:0006909	215	0.022
regulation of protein metabolic process	GO:0051246	256	0.022
catabolic process	GO:0009056	409	0.021	Human Rat Fly
negative regulation of signal transduction	GO:0009968	206	0.021
protein transport	GO:0015031	155	0.021
single organism biosynthetic process	GO:0044711	206	0.021
positive regulation of signaling	GO:0023056	243	0.021
regulation of protein modification process	GO:0031399	112	0.021
nucleobase containing small molecule metabolic process	GO:0055086	174	0.021	Human Rat Fly
camera type eye development	GO:0043010	4	0.020
cellular protein localization	GO:0034613	160	0.020
eye development	GO:0001654	323	0.020
protein transmembrane transport	GO:0071806	4	0.020
regulation of multicellular organismal development	GO:2000026	414	0.020
photoreceptor cell differentiation	GO:0046530	170	0.020
embryonic development via the syncytial blastoderm	GO:0001700	148	0.020
body morphogenesis	GO:0010171	2	0.020
transmembrane transport	GO:0055085	139	0.020	Human Rat Fly
regulation of mitotic cell cycle	GO:0007346	190	0.020
regulation of cellular amine metabolic process	GO:0033238	3	0.019
single organism catabolic process	GO:0044712	228	0.019	Human Rat Fly
regulation of localization	GO:0032879	275	0.019	Human
cellular macromolecular complex assembly	GO:0034622	153	0.019
negative regulation of cell communication	GO:0010648	223	0.019
cell proliferation	GO:0008283	299	0.019
regulation of cellular catabolic process	GO:0031329	157	0.019	Human
purine nucleotide metabolic process	GO:0006163	146	0.018	Human Rat Fly
regionalization	GO:0003002	416	0.018
regulation of cell cycle	GO:0051726	291	0.018
cellular catabolic process	GO:0044248	372	0.018	Human Rat Fly
organelle fission	GO:0048285	340	0.018
lateral inhibition	GO:0046331	206	0.018
nucleoside phosphate metabolic process	GO:0006753	162	0.018	Human Rat Fly
compound eye development	GO:0048749	307	0.017
positive regulation of rna biosynthetic process	GO:1902680	266	0.017
ras protein signal transduction	GO:0007265	88	0.017
cellular nitrogen compound catabolic process	GO:0044270	165	0.017	Human Rat Fly
cellular macromolecule catabolic process	GO:0044265	136	0.017
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.017	Human
regulation of phosphorus metabolic process	GO:0051174	210	0.017	Human
sterol homeostasis	GO:0055092	4	0.017
regulation of response to stress	GO:0080134	200	0.017
establishment of protein localization	GO:0045184	163	0.017
negative regulation of gene expression	GO:0010629	387	0.017
organelle assembly	GO:0070925	198	0.017
regulation of immune system process	GO:0002682	176	0.017
small gtpase mediated signal transduction	GO:0007264	88	0.017
male gamete generation	GO:0048232	201	0.017
regulation of phosphate metabolic process	GO:0019220	210	0.017	Human
positive regulation of signal transduction	GO:0009967	223	0.017
response to radiation	GO:0009314	155	0.016
spermatogenesis	GO:0007283	200	0.016
ribonucleoside metabolic process	GO:0009119	127	0.016	Human Rat Fly
nucleoside triphosphate metabolic process	GO:0009141	120	0.016	Human Rat Fly
positive regulation of cellular biosynthetic process	GO:0031328	316	0.016
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.016	Human
developmental maturation	GO:0021700	172	0.016
negative regulation of signaling	GO:0023057	219	0.016
posttranscriptional regulation of gene expression	GO:0010608	145	0.016	Human
eye morphogenesis	GO:0048592	260	0.016
negative regulation of cellular metabolic process	GO:0031324	382	0.016
retina development in camera type eye	GO:0060041	4	0.016
nucleobase containing compound catabolic process	GO:0034655	165	0.015	Human Rat Fly
aromatic compound catabolic process	GO:0019439	166	0.015	Human Rat Fly
segmentation	GO:0035282	207	0.015
positive regulation of phosphate metabolic process	GO:0045937	139	0.015	Human
regulation of cell cycle process	GO:0010564	181	0.015
compound eye morphogenesis	GO:0001745	249	0.015
positive regulation of macromolecule metabolic process	GO:0010604	405	0.015
mitotic nuclear division	GO:0007067	213	0.015
homeostatic process	GO:0042592	199	0.015	Human
purine ribonucleotide metabolic process	GO:0009150	145	0.015	Human Rat Fly
regulation of cellular ketone metabolic process	GO:0010565	3	0.015
rna processing	GO:0006396	147	0.015
regulation of nervous system development	GO:0051960	248	0.015
chromosome organization	GO:0051276	360	0.015
forebrain development	GO:0030900	2	0.015
glycosyl compound catabolic process	GO:1901658	112	0.015	Human Rat Fly
transcription from rna polymerase ii promoter	GO:0006366	368	0.015
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.015
chemotaxis	GO:0006935	249	0.015
axis specification	GO:0009798	167	0.014
single organism intracellular transport	GO:1902582	207	0.014
positive regulation of transcription dna templated	GO:0045893	266	0.014
amine metabolic process	GO:0009308	12	0.014
cellular amine metabolic process	GO:0044106	12	0.014
telencephalon development	GO:0021537	2	0.014
macromolecule catabolic process	GO:0009057	161	0.014
ion transmembrane transport	GO:0034220	122	0.014	Human Rat Fly
regulation of intracellular signal transduction	GO:1902531	236	0.014
kidney development	GO:0001822	3	0.014
gland development	GO:0048732	191	0.014
cognition	GO:0050890	141	0.014
ribonucleotide metabolic process	GO:0009259	145	0.014	Human Rat Fly
regulation of anatomical structure morphogenesis	GO:0022603	242	0.014
cellular response to chemical stimulus	GO:0070887	199	0.014
regulation of catabolic process	GO:0009894	170	0.014	Human
response to other organism	GO:0051707	293	0.014	Rat
negative regulation of response to stimulus	GO:0048585	258	0.014
taxis	GO:0042330	304	0.014
regulation of mapk cascade	GO:0043408	92	0.014
immune response	GO:0006955	246	0.014
axon development	GO:0061564	297	0.014
cellular amino acid metabolic process	GO:0006520	61	0.014
blastoderm segmentation	GO:0007350	159	0.014
positive regulation of gene expression	GO:0010628	290	0.013
cellular response to dna damage stimulus	GO:0006974	223	0.013
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.013	Human Rat Fly
positive regulation of biosynthetic process	GO:0009891	316	0.013
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.013
regulation of protein phosphorylation	GO:0001932	64	0.013
response to organic substance	GO:0010033	284	0.013	Rat
nuclear division	GO:0000280	332	0.013
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.013
cellularization	GO:0007349	90	0.013
organic cyclic compound catabolic process	GO:1901361	168	0.013	Human Rat Fly
cell death	GO:0008219	279	0.013
gene silencing	GO:0016458	138	0.013
positive regulation of rna metabolic process	GO:0051254	271	0.013
cell cycle phase transition	GO:0044770	140	0.013
wnt signaling pathway	GO:0016055	98	0.013
detection of stimulus involved in sensory perception	GO:0050906	92	0.013
axonogenesis	GO:0007409	290	0.013
intracellular protein transmembrane transport	GO:0065002	4	0.013
cell division	GO:0051301	248	0.013
single organism carbohydrate metabolic process	GO:0044723	72	0.013
positive regulation of phosphorus metabolic process	GO:0010562	139	0.013	Human
regulation of multi organism process	GO:0043900	131	0.013
axon guidance	GO:0007411	233	0.013
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.013	Human Rat Fly
olfactory learning	GO:0008355	56	0.013
positive regulation of cell motility	GO:2000147	3	0.013
spindle organization	GO:0007051	253	0.013
protein complex assembly	GO:0006461	200	0.013
nucleoside catabolic process	GO:0009164	112	0.013	Human Rat Fly
single organism behavior	GO:0044708	391	0.012
regulation of ras protein signal transduction	GO:0046578	93	0.012
positive regulation of cellular amine metabolic process	GO:0033240	0	0.012
cellular homeostasis	GO:0019725	80	0.012	Human
embryonic pattern specification	GO:0009880	174	0.012
heterocycle catabolic process	GO:0046700	166	0.012	Human Rat Fly
negative regulation of developmental process	GO:0051093	201	0.012
compound eye photoreceptor cell differentiation	GO:0001751	140	0.012
programmed cell death	GO:0012501	257	0.012
sperm individualization	GO:0007291	48	0.012
eye photoreceptor cell differentiation	GO:0001754	145	0.012
negative regulation of cellular biosynthetic process	GO:0031327	277	0.012
cellular ketone metabolic process	GO:0042180	24	0.012
embryo development ending in birth or egg hatching	GO:0009792	152	0.012
response to lipopolysaccharide	GO:0032496	4	0.012	Rat
protein modification by small protein conjugation or removal	GO:0070647	106	0.012
cilium organization	GO:0044782	41	0.012
negative regulation of protein metabolic process	GO:0051248	85	0.012
regulation of cell differentiation	GO:0045595	302	0.012
regulation of organelle organization	GO:0033043	196	0.012
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.012
glycosyl compound metabolic process	GO:1901657	127	0.012	Human Rat Fly
chromatin organization	GO:0006325	207	0.012
instar larval development	GO:0002168	55	0.012
proteolysis	GO:0006508	192	0.012
purine containing compound metabolic process	GO:0072521	155	0.012	Human Rat Fly
phosphate ion transport	GO:0006817	4	0.012
carbohydrate metabolic process	GO:0005975	82	0.012
hematopoietic progenitor cell differentiation	GO:0002244	1	0.012
intracellular transport	GO:0046907	228	0.012
regulation of cellular amino acid metabolic process	GO:0006521	0	0.012
ribose phosphate metabolic process	GO:0019693	145	0.012	Human Rat Fly
synaptic growth at neuromuscular junction	GO:0051124	119	0.012
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.012	Human Rat Fly
peptidyl amino acid modification	GO:0018193	105	0.012
response to temperature stimulus	GO:0009266	106	0.011
cell maturation	GO:0048469	144	0.011
response to glucose	GO:0009749	2	0.011
regulation of immune response	GO:0050776	118	0.011
purine ribonucleoside metabolic process	GO:0046128	127	0.011	Human Rat Fly
nucleotide metabolic process	GO:0009117	161	0.011	Human Rat Fly
protein localization to organelle	GO:0033365	82	0.011
positive regulation of intracellular signal transduction	GO:1902533	116	0.011
regulation of programmed cell death	GO:0043067	152	0.011
monocarboxylic acid transport	GO:0015718	3	0.011
developmental growth	GO:0048589	280	0.011
regulation of i kappab kinase nf kappab signaling	GO:0043122	2	0.011
establishment of protein localization to organelle	GO:0072594	62	0.011
macromolecular complex assembly	GO:0065003	256	0.011
regulation of transport	GO:0051049	181	0.011	Human
morphogenesis of an epithelium	GO:0002009	276	0.011
death	GO:0016265	284	0.011
purine nucleoside metabolic process	GO:0042278	127	0.011	Human Rat Fly
actin filament based process	GO:0030029	220	0.011
cellular component assembly involved in morphogenesis	GO:0010927	151	0.011
cilium morphogenesis	GO:0060271	39	0.011
negative regulation of cell differentiation	GO:0045596	143	0.011
axoneme assembly	GO:0035082	18	0.011
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.011
dna metabolic process	GO:0006259	227	0.011
mrna metabolic process	GO:0016071	124	0.011
regulation of kinase activity	GO:0043549	53	0.011
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.011
proteolysis involved in cellular protein catabolic process	GO:0051603	83	0.011
cellular lipid metabolic process	GO:0044255	83	0.011
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.011
mitotic cell cycle checkpoint	GO:0007093	88	0.011
photoreceptor cell development	GO:0042461	96	0.011
regulation of cell death	GO:0010941	173	0.011
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.011
nucleoside phosphate catabolic process	GO:1901292	110	0.011	Human Rat Fly
actin cytoskeleton organization	GO:0030036	206	0.011
mating	GO:0007618	120	0.011
regulation of transferase activity	GO:0051338	58	0.011
mitotic cell cycle phase transition	GO:0044772	138	0.011
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.011	Human Rat Fly
protein complex biogenesis	GO:0070271	201	0.011
nucleoside metabolic process	GO:0009116	127	0.011	Human Rat Fly
synaptic transmission	GO:0007268	288	0.011
somatic muscle development	GO:0007525	66	0.010
mapk cascade	GO:0000165	107	0.010
anterior posterior axis specification embryo	GO:0008595	103	0.010
dendrite morphogenesis	GO:0048813	199	0.010
carbohydrate derivative biosynthetic process	GO:1901137	85	0.010
negative regulation of cellular protein metabolic process	GO:0032269	85	0.010
negative regulation of cell cycle phase transition	GO:1901988	103	0.010
chemosensory behavior	GO:0007635	106	0.010
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.010
dorsal ventral pattern formation	GO:0009953	133	0.010
dendrite development	GO:0016358	204	0.010
tripartite regional subdivision	GO:0007351	103	0.010
regulation of cell development	GO:0060284	215	0.010
cell projection assembly	GO:0030031	94	0.010
regulation of cell cycle phase transition	GO:1901987	130	0.010
nucleotide catabolic process	GO:0009166	109	0.010	Human Rat Fly
negative regulation of rna biosynthetic process	GO:1902679	240	0.010
positive regulation of multicellular organismal process	GO:0051240	143	0.010
positive regulation of catabolic process	GO:0009896	105	0.010	Human
regulation of notch signaling pathway	GO:0008593	100	0.010
response to oxygen containing compound	GO:1901700	200	0.010	Rat
positive regulation of phosphorylation	GO:0042327	87	0.010
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.010
response to bacterium	GO:0009617	198	0.010	Rat
signal transduction by phosphorylation	GO:0023014	107	0.010

CG5250 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.049
nervous system disease	DOID:863	0.026
sensory system disease	DOID:0050155	0.016
musculoskeletal system disease	DOID:17	0.013
eye and adnexa disease	DOID:1492	0.013
eye disease	DOID:5614	0.013
disease of metabolism	DOID:0014667	0.010

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