Drosophila melanogaster

12 known processes

Toll-4 (Dmel_CG18241)

CG18241 gene product from transcript CG18241-RA

(Aliases: dToll4,CT29238,Tl-4,dTLR4,TL4,Dmel\CG18241,toll,CG18241)

Toll-4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
neurological system processGO:00508773580.059
epithelial cell differentiationGO:00308553220.049
detection of stimulusGO:00516061560.045
positive regulation of rna biosynthetic processGO:19026802660.040
response to external biotic stimulusGO:00432072930.038
Fly
detection of stimulus involved in sensory perceptionGO:0050906920.038
positive regulation of nucleobase containing compound metabolic processGO:00459353320.038
response to other organismGO:00517072930.037
Fly
positive regulation of nitrogen compound metabolic processGO:00511733540.037
Fly
epithelial cell developmentGO:00020642740.037
positive regulation of nucleic acid templated transcriptionGO:19035082660.037
transcription from rna polymerase ii promoterGO:00063663680.037
positive regulation of rna metabolic processGO:00512542710.036
small molecule metabolic processGO:00442813050.036
appendage developmentGO:00487364010.035
imaginal disc derived appendage developmentGO:00487373990.034
regulation of transcription from rna polymerase ii promoterGO:00063573780.034
sensory perception of smellGO:0007608800.034
wing disc morphogenesisGO:00074723440.034
imaginal disc derived appendage morphogenesisGO:00351143950.034
positive regulation of biosynthetic processGO:00098913160.034
Fly
organic substance transportGO:00717022570.033
columnar cuboidal epithelial cell differentiationGO:00020652560.033
establishment of localization in cellGO:00516494020.033
positive regulation of macromolecule biosynthetic processGO:00105572830.032
positive regulation of macromolecule metabolic processGO:00106044050.032
post embryonic appendage morphogenesisGO:00351203850.032
positive regulation of cellular biosynthetic processGO:00313283160.031
Fly
single organism behaviorGO:00447083910.031
appendage morphogenesisGO:00351073970.031
negative regulation of rna metabolic processGO:00512532510.031
imaginal disc derived wing morphogenesisGO:00074763370.031
cellular protein modification processGO:00064644380.031
positive regulation of transcription dna templatedGO:00458932660.031
organonitrogen compound metabolic processGO:19015643180.031
Fly
sensory perception of chemical stimulusGO:00076061160.031
negative regulation of nitrogen compound metabolic processGO:00511722650.030
detection of chemical stimulus involved in sensory perception of smellGO:0050911500.029
sensory perceptionGO:00076001960.029
compound eye developmentGO:00487493070.029
positive regulation of gene expressionGO:00106282900.028
negative regulation of cellular metabolic processGO:00313243820.028
regulation of cell cycleGO:00517262910.028
detection of chemical stimulusGO:0009593930.027
response to biotic stimulusGO:00096072940.027
Fly
forebrain developmentGO:003090020.027
response to oxygen containing compoundGO:19017002000.027
organelle fissionGO:00482853400.027
single organism biosynthetic processGO:00447112060.026
regulation of localizationGO:00328792750.026
catabolic processGO:00090564090.026
protein modification processGO:00362114380.026
negative regulation of rna biosynthetic processGO:19026792400.026
response to abiotic stimulusGO:00096283410.025
organic substance catabolic processGO:19015753080.025
negative regulation of gene expressionGO:00106293870.025
nuclear divisionGO:00002803320.025
detection of chemical stimulus involved in sensory perceptionGO:0050907750.025
cellular amine metabolic processGO:0044106120.024
cell deathGO:00082192790.024
columnar cuboidal epithelial cell developmentGO:00020662490.024
negative regulation of nucleobase containing compound metabolic processGO:00459342610.024
negative regulation of biosynthetic processGO:00098902770.024
regulation of cell cycle processGO:00105641810.023
deathGO:00162652840.023
body morphogenesisGO:001017120.023
g protein coupled receptor signaling pathwayGO:00071861360.023
positive regulation of response to stimulusGO:00485843230.023
Fly
ovarian follicle cell developmentGO:00307072480.023
endocytosisGO:00068973100.022
cell motilityGO:00488702510.022
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.022
positive regulation of cell communicationGO:00106472500.022
morphogenesis of an epitheliumGO:00020092760.022
gland developmentGO:00487321910.022
negative regulation of nucleic acid templated transcriptionGO:19035072400.022
cellular catabolic processGO:00442483720.022
negative regulation of response to stimulusGO:00485852580.022
dendrite developmentGO:00163582040.021
regulation of multicellular organismal developmentGO:20000264140.021
response to lipopolysaccharideGO:003249640.021
eye morphogenesisGO:00485922600.021
eye developmentGO:00016543230.021
intracellular signal transductionGO:00355563000.021
growthGO:00400073590.021
developmental growthGO:00485892800.021
localization of cellGO:00516742570.021
positive regulation of signalingGO:00230562430.021
defense responseGO:00069523000.020
Fly
regulation of cellular amine metabolic processGO:003323830.020
cell divisionGO:00513012480.020
negative regulation of signal transductionGO:00099682060.020
negative regulation of cell communicationGO:00106482230.020
response to bacteriumGO:00096171980.020
regulation of protein metabolic processGO:00512462560.020
response to organic substanceGO:00100332840.020
embryonic morphogenesisGO:00485982060.020
amine metabolic processGO:0009308120.020
chromosome organizationGO:00512763600.020
programmed cell deathGO:00125012570.020
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.020
cellular amino acid metabolic processGO:0006520610.019
negative regulation of macromolecule biosynthetic processGO:00105582700.019
regulation of mitotic cell cycleGO:00073461900.019
camera type eye developmentGO:004301040.019
organic acid metabolic processGO:00060821030.019
organic hydroxy compound metabolic processGO:1901615830.019
carboxylic acid metabolic processGO:0019752920.019
ameboidal type cell migrationGO:00016671510.019
regionalizationGO:00030024160.019
regulation of molecular functionGO:00650092170.019
negative regulation of cellular biosynthetic processGO:00313272770.019
oxoacid metabolic processGO:00434361030.019
cell proliferationGO:00082832990.019
organophosphate metabolic processGO:00196371950.019
carbohydrate derivative metabolic processGO:19011352170.018
tissue morphogenesisGO:00487292970.018
kidney developmentGO:000182230.018
olfactory behaviorGO:0042048970.018
regulation of organelle organizationGO:00330431960.018
vesicle mediated transportGO:00161923810.018
mitotic nuclear divisionGO:00070672130.018
spindle organizationGO:00070512530.018
dendrite morphogenesisGO:00488131990.018
negative regulation of transcription dna templatedGO:00458922370.018
response to radiationGO:00093141550.018
protein localizationGO:00081042840.018
homeostatic processGO:00425921990.018
developmental programmed cell deathGO:00106231380.018
negative regulation of developmental processGO:00510932010.018
response to light stimulusGO:00094161240.017
regulation of catalytic activityGO:00507901850.017
eggshell formationGO:00307031050.017
macromolecular complex assemblyGO:00650032560.017
phosphorylationGO:00163102940.017
intracellular transportGO:00469072280.017
negative regulation of signalingGO:00230572190.017
sensory organ morphogenesisGO:00905962600.017
salivary gland developmentGO:00074311620.017
embryonic development via the syncytial blastodermGO:00017001480.017
positive regulation of signal transductionGO:00099672230.017
regulation of transportGO:00510491810.017
single organism intracellular transportGO:19025822070.017
telencephalon developmentGO:002153720.016
respiratory system developmentGO:00605412130.016
positive regulation of transportGO:0051050920.016
phagocytosisGO:00069092150.016
exocrine system developmentGO:00352721620.016
regulation of intracellular signal transductionGO:19025312360.016
regulation of anatomical structure sizeGO:00900661630.016
immune system processGO:00023763470.016
Fly
chemosensory behaviorGO:00076351060.016
ion transmembrane transportGO:00342201220.016
cell cell signaling involved in cell fate commitmentGO:00451682100.016
cellular response to chemical stimulusGO:00708871990.016
salivary gland morphogenesisGO:00074351450.016
cellular macromolecule localizationGO:00707272200.016
compound eye morphogenesisGO:00017452490.016
positive regulation of cell migrationGO:003033520.016
actin filament organizationGO:00070151260.016
defense response to bacteriumGO:00427421780.016
matingGO:00076181200.016
cellular component assembly involved in morphogenesisGO:00109271510.016
eye photoreceptor cell differentiationGO:00017541450.016
taxisGO:00423303040.015
monocarboxylic acid transportGO:001571830.015
protein complex assemblyGO:00064612000.015
regulation of cellular ketone metabolic processGO:001056530.015
regulation of cellular protein metabolic processGO:00322682430.015
regulation of cellular component biogenesisGO:00440872010.015
multi multicellular organism processGO:00447061230.015
cell migrationGO:00164772380.015
chemotaxisGO:00069352490.015
axon developmentGO:00615642970.015
nucleobase containing small molecule metabolic processGO:00550861740.015
cellular ketone metabolic processGO:0042180240.015
hindbrain developmentGO:003090220.015
embryo development ending in birth or egg hatchingGO:00097921520.015
positive regulation of intracellular signal transductionGO:19025331160.014
lipid metabolic processGO:00066291210.014
regulation of cell differentiationGO:00455953020.014
proteolysisGO:00065081920.014
regulation of phosphorus metabolic processGO:00511742100.014
cellular response to dna damage stimulusGO:00069742230.014
signal transduction by phosphorylationGO:00230141070.014
single organism catabolic processGO:00447122280.014
transmembrane transportGO:00550851390.014
defense response to other organismGO:00985422250.014
nucleotide metabolic processGO:00091171610.014
regulation of nervous system developmentGO:00519602480.014
open tracheal system developmentGO:00074242040.014
connective tissue developmentGO:006144830.014
locomotory behaviorGO:00076261760.014
protein heterooligomerizationGO:005129140.014
central nervous system developmentGO:00074172010.014
multi organism behaviorGO:00517051750.014
Fly
photoreceptor cell differentiationGO:00465301700.014
regulation of cellular localizationGO:00603411360.014
actin filament based processGO:00300292200.014
response to organophosphorusGO:004668320.014
gland morphogenesisGO:00226121450.014
mitotic spindle organizationGO:00070522200.014
positive regulation of cell motilityGO:200014730.014
cellular response to organic substanceGO:00713101320.014
regulation of growthGO:00400082330.013
retina development in camera type eyeGO:006004140.013
nucleoside phosphate metabolic processGO:00067531620.013
axon guidanceGO:00074112330.013
gene silencingGO:00164581380.013
purine containing compound metabolic processGO:00725211550.013
positive regulation of multicellular organismal processGO:00512401430.013
dna metabolic processGO:00062592270.013
developmental maturationGO:00217001720.013
ethanolamine containing compound metabolic processGO:004243940.013
immune response activating signal transductionGO:000275720.013
tube morphogenesisGO:00352391910.013
establishment of protein localizationGO:00451841630.013
apoptotic processGO:00069151590.013
biological adhesionGO:00226101380.013
response to endogenous stimulusGO:00097191190.013
synaptic transmissionGO:00072682880.013
pigmentationGO:0043473750.013
protein transportGO:00150311550.013
tissue deathGO:00162711020.013
segmentationGO:00352822070.013
mapk cascadeGO:00001651070.013
neuron recognitionGO:00080381010.013
regulation of cell proliferationGO:00421271630.013
cellular response to molecule of bacterial originGO:007121930.013
negative regulation of nervous system developmentGO:0051961920.013
regulation of phosphate metabolic processGO:00192202100.013
protein complex biogenesisGO:00702712010.012
autophagic cell deathGO:0048102830.012
wnt signaling pathwayGO:0016055980.012
salivary gland histolysisGO:0035070880.012
anatomical structure homeostasisGO:0060249970.012
response to alcoholGO:0097305950.012
regulation of mapk cascadeGO:0043408920.012
spermatogenesisGO:00072832000.012
chromatin organizationGO:00063252070.012
embryonic pattern specificationGO:00098801740.012
regulation of developmental growthGO:00486381740.012
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.012
negative regulation of cellular component organizationGO:00511291080.012
compound eye photoreceptor cell differentiationGO:00017511400.012
photoreceptor cell developmentGO:0042461960.012
sterol homeostasisGO:005509240.012
positive regulation of cellular component organizationGO:00511301560.012
positive regulation of catalytic activityGO:00430851180.012
regulation of programmed cell deathGO:00430671520.012
adult locomotory behaviorGO:0008344760.012
carbohydrate derivative biosynthetic processGO:1901137850.012
tube developmentGO:00352952440.012
negative regulation of multicellular organismal processGO:00512411420.012
regulation of cell deathGO:00109411730.012
actin cytoskeleton organizationGO:00300362060.012
regulation of immune system processGO:00026821760.012
Fly
ribonucleotide metabolic processGO:00092591450.012
endomembrane system organizationGO:00102561190.012
positive regulation of molecular functionGO:00440931360.012
secretionGO:00469031090.012
neuron projection guidanceGO:00974852410.012
chromosome segregationGO:00070591570.012
cellular protein localizationGO:00346131600.012
axonogenesisGO:00074092900.012
regulation of lipid transportGO:003236830.012
regulation of anatomical structure morphogenesisGO:00226032420.012
cellular response to lipopolysaccharideGO:007122230.012
adult behaviorGO:00305341370.012
organonitrogen compound biosynthetic processGO:19015661170.012
Fly
regulation of cellular amino acid metabolic processGO:000652100.011
salivary gland cell autophagic cell deathGO:0035071830.011
purine nucleotide metabolic processGO:00061631460.011
chorion containing eggshell formationGO:00073041050.011
immune response regulating signaling pathwayGO:000276420.011
positive regulation of phosphorus metabolic processGO:00105621390.011
positive regulation of protein metabolic processGO:00512471280.011
mesenchymal cell differentiationGO:004876210.011
cognitionGO:00508901410.011
chromatin modificationGO:00165681470.011
positive regulation of cellular amine metabolic processGO:003324000.011
regulation of response to stressGO:00801342000.011
lateral inhibitionGO:00463312060.011
regulation of cell morphogenesisGO:00226041630.011
cellular response to carbohydrate stimulusGO:007132240.011
memoryGO:0007613940.011
organonitrogen compound catabolic processGO:19015651280.011
enzyme linked receptor protein signaling pathwayGO:00071671790.011
cellular response to biotic stimulusGO:007121640.011
notch signaling pathwayGO:00072191200.011
regulation of hormone levelsGO:0010817400.011
regulation of mitosisGO:0007088560.011
organelle assemblyGO:00709251980.011
cell fate determinationGO:0001709910.011
cellular homeostasisGO:0019725800.011
leg disc developmentGO:0035218920.011
secretion by cellGO:00329401010.011
digestive tract developmentGO:00485651490.011
cytoplasmic transportGO:00164821300.011
rna processingGO:00063961470.011
maintenance of locationGO:0051235730.011
neuropeptide signaling pathwayGO:0007218450.011
mesenchymal cell developmentGO:001403110.011
hematopoietic progenitor cell differentiationGO:000224410.011
macromolecule catabolic processGO:00090571610.011
establishment or maintenance of cell polarityGO:00071631670.011
regulation of mitotic cell cycle phase transitionGO:19019901300.011
negative regulation of cell cycleGO:00457861160.011
cell recognitionGO:00080371020.011
blastoderm segmentationGO:00073501590.011
synapse organizationGO:00508081960.011
regulation of gene expression epigeneticGO:00400291280.011
negative regulation of mitotic cell cycleGO:00459301090.011
regulation of cell developmentGO:00602842150.011
brain developmentGO:00074201200.011
regulation of cell shapeGO:00083601130.011
negative regulation of cell cycle processGO:00109481090.011
organic cyclic compound catabolic processGO:19013611680.011
regulation of notch signaling pathwayGO:00085931000.011
cell adhesionGO:00071551360.011
negative regulation of cell differentiationGO:00455961430.011
response to nitrogen compoundGO:1901698900.011
mitotic cell cycle phase transitionGO:00447721380.011
protein phosphorylationGO:00064681690.010
positive regulation of phosphorylationGO:0042327870.010
regulation of behaviorGO:0050795750.010
lipid localizationGO:0010876540.010
nephron developmentGO:007200630.010
regulation of epithelial cell differentiationGO:003085640.010
immune responseGO:00069552460.010
Fly
chemical homeostasisGO:0048878920.010
epithelial cell migrationGO:00106311480.010
camera type eye morphogenesisGO:004859320.010
positive regulation of phosphate metabolic processGO:00459371390.010
positive regulation of cellular component biogenesisGO:0044089800.010
cholesterol transportGO:003030120.010
tissue migrationGO:00901301550.010
aromatic compound catabolic processGO:00194391660.010
cholesterol homeostasisGO:004263230.010
regulation of gene silencingGO:0060968630.010
hormone catabolic processGO:004244730.010
ribose phosphate metabolic processGO:00196931450.010
digestive system developmentGO:00551231490.010
regulation of hydrolase activityGO:0051336970.010
negative regulation of cell cycle phase transitionGO:19019881030.010
regulation of phosphorylationGO:00423251470.010
spinal cord developmentGO:002151010.010
heterocycle catabolic processGO:00467001660.010

Toll-4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.052
nervous system diseaseDOID:86300.018
disease of metabolismDOID:001466700.017
musculoskeletal system diseaseDOID:1700.016
inherited metabolic disorderDOID:65500.012
acquired metabolic diseaseDOID:006015800.012
connective tissue diseaseDOID:6500.011
bone diseaseDOID:008000100.010