IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

UGP (Dmel_CG4347)

CG4347 gene product from transcript CG4347-RE

(Aliases: UDPGPP,Dmel\CG4347,CG4347,UGPase)

FLYBASE: FBgn0035978
Entrez: 39065
UniProtKB: A5XCL5
UniProtKB: E1JI91
UniProtKB: Q9VSW1
UniProtKB: Q9VSW2

Process Predictions
Disease Predictions

UGP biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
negative regulation of gene expression	GO:0010629	387	0.077
lateral inhibition	GO:0046331	206	0.072
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.070
organic substance transport	GO:0071702	257	0.064
ion transmembrane transport	GO:0034220	122	0.063
ion transport	GO:0006811	145	0.060
response to oxygen containing compound	GO:1901700	200	0.055
regulation of multicellular organismal development	GO:2000026	414	0.043
homeostatic process	GO:0042592	199	0.042
single organism behavior	GO:0044708	391	0.041
carboxylic acid metabolic process	GO:0019752	92	0.040
response to alcohol	GO:0097305	95	0.040
organonitrogen compound metabolic process	GO:1901564	318	0.039
inorganic ion transmembrane transport	GO:0098660	73	0.037
l amino acid import	GO:0043092	2	0.037
carbohydrate metabolic process	GO:0005975	82	0.037
response to organic substance	GO:0010033	284	0.037
body morphogenesis	GO:0010171	2	0.037
cellular protein modification process	GO:0006464	438	0.036
positive regulation of cell communication	GO:0010647	250	0.036
establishment of localization in cell	GO:0051649	402	0.035
positive regulation of cellular biosynthetic process	GO:0031328	316	0.035
single organism carbohydrate metabolic process	GO:0044723	72	0.035
wing disc morphogenesis	GO:0007472	344	0.035
transmembrane transport	GO:0055085	139	0.033
appendage development	GO:0048736	401	0.032
neurological system process	GO:0050877	358	0.032
metal ion homeostasis	GO:0055065	44	0.032
regulation of steroid metabolic process	GO:0019218	2	0.030
positive regulation of biosynthetic process	GO:0009891	316	0.030
regionalization	GO:0003002	416	0.029
positive regulation of macromolecule metabolic process	GO:0010604	405	0.028
regulation of cellular ketone metabolic process	GO:0010565	3	0.028
dorsal ventral pattern formation	GO:0009953	133	0.027
response to hexose	GO:0009746	3	0.027
post embryonic appendage morphogenesis	GO:0035120	385	0.027
imaginal disc derived appendage development	GO:0048737	399	0.027
appendage morphogenesis	GO:0035107	397	0.026
imaginal disc derived wing morphogenesis	GO:0007476	337	0.026
positive regulation of response to stimulus	GO:0048584	323	0.026
forebrain development	GO:0030900	2	0.025
spermatogenesis	GO:0007283	200	0.024
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.024
small molecule metabolic process	GO:0044281	305	0.024
connective tissue development	GO:0061448	3	0.024
carboxylic acid transport	GO:0046942	18	0.024
organic acid metabolic process	GO:0006082	103	0.024
response to glucose	GO:0009749	2	0.024
single organism biosynthetic process	GO:0044711	206	0.023
multi organism behavior	GO:0051705	175	0.023
phagocytosis	GO:0006909	215	0.023
protein modification process	GO:0036211	438	0.023
cellular catabolic process	GO:0044248	372	0.023
vesicle mediated transport	GO:0016192	381	0.022
response to abiotic stimulus	GO:0009628	341	0.022
regulation of cell differentiation	GO:0045595	302	0.022
negative regulation of cellular metabolic process	GO:0031324	382	0.022
oxoacid metabolic process	GO:0043436	103	0.022
regulation of developmental growth	GO:0048638	174	0.021
response to lipopolysaccharide	GO:0032496	4	0.021
secretion by cell	GO:0032940	101	0.021
epithelial cell differentiation	GO:0030855	322	0.021
organic substance catabolic process	GO:1901575	308	0.021
acyl coa metabolic process	GO:0006637	3	0.020
telencephalon development	GO:0021537	2	0.020
embryonic morphogenesis	GO:0048598	206	0.020
anion transport	GO:0006820	41	0.020
carbohydrate biosynthetic process	GO:0016051	17	0.020
response to nitrogen compound	GO:1901698	90	0.020
regulation of localization	GO:0032879	275	0.020
positive regulation of signal transduction	GO:0009967	223	0.020
catabolic process	GO:0009056	409	0.019
posttranscriptional regulation of gene expression	GO:0010608	145	0.019
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.019
cellular response to chemical stimulus	GO:0070887	199	0.019
endocytosis	GO:0006897	310	0.019
regulation of cell cycle	GO:0051726	291	0.019
carbohydrate derivative metabolic process	GO:1901135	217	0.019
regulation of nervous system development	GO:0051960	248	0.019
positive regulation of transport	GO:0051050	92	0.019
single organism catabolic process	GO:0044712	228	0.018
intracellular signal transduction	GO:0035556	300	0.018
chemical homeostasis	GO:0048878	92	0.018
response to monosaccharide	GO:0034284	4	0.018
behavioral response to ethanol	GO:0048149	49	0.018
cation transport	GO:0006812	110	0.018
phosphate ion transport	GO:0006817	4	0.018
transcription from rna polymerase ii promoter	GO:0006366	368	0.018
regulation of protein metabolic process	GO:0051246	256	0.018
protein localization	GO:0008104	284	0.017
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.017
positive regulation of lipid metabolic process	GO:0045834	4	0.017
wing disc pattern formation	GO:0035222	66	0.017
response to ethanol	GO:0045471	59	0.017
camera type eye development	GO:0043010	4	0.017
monocarboxylic acid metabolic process	GO:0032787	29	0.016
anatomical structure homeostasis	GO:0060249	97	0.016
steroid catabolic process	GO:0006706	1	0.016
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.016
regulation of cell development	GO:0060284	215	0.016
male gamete generation	GO:0048232	201	0.016
negative regulation of cell differentiation	GO:0045596	143	0.016
single organism intracellular transport	GO:1902582	207	0.016
cellular ketone metabolic process	GO:0042180	24	0.016
nitrogen compound transport	GO:0071705	85	0.015
cellular protein localization	GO:0034613	160	0.015
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.015
cellular amino acid metabolic process	GO:0006520	61	0.015
positive regulation of catalytic activity	GO:0043085	118	0.015
response to organic cyclic compound	GO:0014070	89	0.015
cellular homeostasis	GO:0019725	80	0.015
organic cyclic compound catabolic process	GO:1901361	168	0.015
response to oxygen levels	GO:0070482	59	0.015
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.015
organic anion transport	GO:0015711	28	0.014
negative regulation of developmental process	GO:0051093	201	0.014
cellular chemical homeostasis	GO:0055082	40	0.014
meiotic cell cycle process	GO:1903046	132	0.014
ion homeostasis	GO:0050801	55	0.014
sulfur compound metabolic process	GO:0006790	59	0.014
tube morphogenesis	GO:0035239	191	0.014
regulation of intracellular signal transduction	GO:1902531	236	0.014
metal ion transport	GO:0030001	74	0.014
response to endogenous stimulus	GO:0009719	119	0.014
tube development	GO:0035295	244	0.014
negative regulation of rna metabolic process	GO:0051253	251	0.014
regulation of anatomical structure morphogenesis	GO:0022603	242	0.014
organonitrogen compound biosynthetic process	GO:1901566	117	0.014
cell proliferation	GO:0008283	299	0.014
organelle fission	GO:0048285	340	0.014
thioester metabolic process	GO:0035383	3	0.013
regulation of cellular amine metabolic process	GO:0033238	3	0.013
dorsal ventral pattern formation imaginal disc	GO:0007450	51	0.013
negative regulation of cellular biosynthetic process	GO:0031327	277	0.013
negative regulation of multicellular organismal process	GO:0051241	142	0.013
positive regulation of signaling	GO:0023056	243	0.013
taxis	GO:0042330	304	0.013
response to inorganic substance	GO:0010035	44	0.013
spindle organization	GO:0007051	253	0.013
cation transmembrane transport	GO:0098655	88	0.013
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.013
cellular response to hexose stimulus	GO:0071331	1	0.013
gene silencing	GO:0016458	138	0.013
positive regulation of rna biosynthetic process	GO:1902680	266	0.013
acylglycerol biosynthetic process	GO:0046463	2	0.013
aging	GO:0007568	143	0.013
cellular component assembly involved in morphogenesis	GO:0010927	151	0.013
cellular protein complex assembly	GO:0043623	71	0.013
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.013
imaginal disc pattern formation	GO:0007447	91	0.013
nucleotide metabolic process	GO:0009117	161	0.013
negative regulation of signaling	GO:0023057	219	0.013
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.012
actin cytoskeleton organization	GO:0030036	206	0.012
divalent inorganic cation homeostasis	GO:0072507	29	0.012
regulation of transport	GO:0051049	181	0.012
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.012
somatic muscle development	GO:0007525	66	0.012
generation of precursor metabolites and energy	GO:0006091	42	0.012
response to organophosphorus	GO:0046683	2	0.012
gliogenesis	GO:0042063	80	0.012
cellular lipid metabolic process	GO:0044255	83	0.012
inorganic cation transmembrane transport	GO:0098662	61	0.012
wing disc dorsal ventral pattern formation	GO:0048190	47	0.012
cellular macromolecule catabolic process	GO:0044265	136	0.012
localization of cell	GO:0051674	257	0.012
response to nutrient levels	GO:0031667	114	0.012
cation homeostasis	GO:0055080	51	0.012
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.012
positive regulation of multicellular organismal process	GO:0051240	143	0.012
adult behavior	GO:0030534	137	0.012
central nervous system development	GO:0007417	201	0.012
sensory perception	GO:0007600	196	0.011
kidney development	GO:0001822	3	0.011
gland development	GO:0048732	191	0.011
regulation of growth	GO:0040008	233	0.011
negative regulation of nervous system development	GO:0051961	92	0.011
negative regulation of biosynthetic process	GO:0009890	277	0.011
phosphorylation	GO:0016310	294	0.011
programmed cell death	GO:0012501	257	0.011
regulation of cellular protein metabolic process	GO:0032268	243	0.011
regulation of hydrolase activity	GO:0051336	97	0.011
locomotory behavior	GO:0007626	176	0.011
alditol phosphate metabolic process	GO:0052646	2	0.011
cellular nitrogen compound catabolic process	GO:0044270	165	0.011
cellular amine metabolic process	GO:0044106	12	0.011
death	GO:0016265	284	0.011
epithelial cell development	GO:0002064	274	0.011
negative regulation of transcription dna templated	GO:0045892	237	0.011
stem cell differentiation	GO:0048863	117	0.011
cell division	GO:0051301	248	0.011
intracellular transport	GO:0046907	228	0.011
neutral lipid biosynthetic process	GO:0046460	2	0.011
regulation of cellular localization	GO:0060341	136	0.011
sodium dependent phosphate transport	GO:0044341	2	0.011
carbohydrate derivative biosynthetic process	GO:1901137	85	0.011
protein catabolic process	GO:0030163	101	0.010
response to organonitrogen compound	GO:0010243	75	0.010
digestive tract morphogenesis	GO:0048546	127	0.010
developmental maturation	GO:0021700	172	0.010
cellular response to dna damage stimulus	GO:0006974	223	0.010
digestive tract development	GO:0048565	149	0.010
protein transport	GO:0015031	155	0.010
regulation of anatomical structure size	GO:0090066	163	0.010
response to decreased oxygen levels	GO:0036293	58	0.010
regulation of programmed cell death	GO:0043067	152	0.010
regulation of phosphorus metabolic process	GO:0051174	210	0.010
multicellular organismal aging	GO:0010259	140	0.010

UGP disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.034
acquired metabolic disease	DOID:0060158	0.017
disease of metabolism	DOID:0014667	0.017
glucose metabolism disease	DOID:4194	0.017
carbohydrate metabolism disease	DOID:0050013	0.017
nervous system disease	DOID:863	0.015
musculoskeletal system disease	DOID:17	0.014
inherited metabolic disorder	DOID:655	0.011
diabetes mellitus	DOID:9351	0.010

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