Drosophila melanogaster

72 known processes

Tom34 (Dmel_CG2708)

Translocase of outer membrane 34

(Aliases: l(3)03692,Dmel\CG2708,DmUnc-45,CG2708,unc-45,dunc-45)

Tom34 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
muscle structure developmentGO:00610612240.353
positive regulation of nitrogen compound metabolic processGO:00511733540.218
regulation of anatomical structure sizeGO:00900661630.217
agingGO:00075681430.202
muscle cell differentiationGO:00426921030.154
striated muscle cell differentiationGO:0051146900.145
organelle assemblyGO:00709251980.135
defense responseGO:00069523000.129
regulation of transcription from rna polymerase ii promoterGO:00063573780.110
protein localizationGO:00081042840.106
regulation of cellular component biogenesisGO:00440872010.106
positive regulation of nucleobase containing compound metabolic processGO:00459353320.103
establishment of localization in cellGO:00516494020.101
regulation of cellular component sizeGO:0032535980.100
multi organism behaviorGO:00517051750.099
organic substance transportGO:00717022570.096
vesicle mediated transportGO:00161923810.093
positive regulation of response to stimulusGO:00485843230.092
positive regulation of macromolecule metabolic processGO:00106044050.090
striated muscle cell developmentGO:0055002500.087
muscle system processGO:0003012210.086
organelle fissionGO:00482853400.079
protein complex biogenesisGO:00702712010.078
response to other organismGO:00517072930.076
positive regulation of macromolecule biosynthetic processGO:00105572830.075
defense response to other organismGO:00985422250.073
intracellular signal transductionGO:00355563000.073
muscle cell developmentGO:0055001500.071
single organism cellular localizationGO:19025801800.070
regulation of organelle organizationGO:00330431960.070
adult behaviorGO:00305341370.068
response to biotic stimulusGO:00096072940.065
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.064
endocytosisGO:00068973100.063
sarcomere organizationGO:0045214260.061
actin cytoskeleton organizationGO:00300362060.061
positive regulation of cellular component organizationGO:00511301560.061
response to bacteriumGO:00096171980.061
response to abiotic stimulusGO:00096283410.059
nuclear divisionGO:00002803320.058
establishment of protein localizationGO:00451841630.058
catabolic processGO:00090564090.057
transcription from rna polymerase ii promoterGO:00063663680.056
epithelial cell differentiationGO:00308553220.056
meiotic cytokinesisGO:0033206330.056
embryo development ending in birth or egg hatchingGO:00097921520.055
cell migrationGO:00164772380.054
apoptotic processGO:00069151590.053
determination of adult lifespanGO:00083401370.053
positive regulation of developmental processGO:00510941430.053
developmental maturationGO:00217001720.052
positive regulation of cellular biosynthetic processGO:00313283160.052
regulation of protein complex disassemblyGO:0043244290.051
regulation of blood circulationGO:1903522210.051
positive regulation of signal transductionGO:00099672230.051
multicellular organismal agingGO:00102591400.051
regulation of system processGO:0044057360.051
appendage developmentGO:00487364010.050
purine containing compound catabolic processGO:00725231120.049
autophagic vacuole assemblyGO:000004520.048
striated muscle myosin thick filament assemblyGO:007168830.047
protein modification processGO:00362114380.047
single organism membrane organizationGO:0044802930.047
organonitrogen compound metabolic processGO:19015643180.047
protein phosphorylationGO:00064681690.047
macromolecular complex assemblyGO:00650032560.046
innate immune responseGO:00450871440.046
adult somatic muscle developmentGO:0007527140.045
metal ion transportGO:0030001740.045
small molecule metabolic processGO:00442813050.045
negative regulation of cellular metabolic processGO:00313243820.044
regulation of actin filament depolymerizationGO:003083430.042
cellular component assembly involved in morphogenesisGO:00109271510.041
regulation of cell deathGO:00109411730.041
positive regulation of rna biosynthetic processGO:19026802660.041
single organism catabolic processGO:00447122280.040
heart processGO:0003015370.040
heart developmentGO:0007507820.040
response to external biotic stimulusGO:00432072930.040
regulation of actin filament lengthGO:0030832270.040
regulation of cellular response to stressGO:0080135890.040
axon developmentGO:00615642970.040
actin filament polymerizationGO:0030041270.038
cell maturationGO:00484691440.038
cell deathGO:00082192790.038
regulation of cellular catabolic processGO:00313291570.037
negative regulation of gene expressionGO:00106293870.037
cellular protein modification processGO:00064644380.037
programmed cell deathGO:00125012570.037
negative regulation of nucleic acid templated transcriptionGO:19035072400.036
intracellular transportGO:00469072280.036
cell motilityGO:00488702510.036
cellular metal ion homeostasisGO:0006875310.035
purine ribonucleoside triphosphate metabolic processGO:00092051190.035
cell proliferationGO:00082832990.035
myofibril assemblyGO:0030239360.035
regulation of localizationGO:00328792750.035
regulation of response to stressGO:00801342000.035
cardiovascular system developmentGO:0072358820.035
mitochondrion degradationGO:000042280.034
positive regulation of biosynthetic processGO:00098913160.034
cytoplasm organizationGO:0007028640.034
protein transportGO:00150311550.034
positive regulation of signalingGO:00230562430.034
synaptic transmissionGO:00072682880.034
actomyosin structure organizationGO:0031032560.034
protein complex assemblyGO:00064612000.034
anatomical structure homeostasisGO:0060249970.034
oocyte developmentGO:00485991240.033
regulation of programmed cell deathGO:00430671520.033
regulation of cellular response to oxidative stressGO:190040740.033
cellular homeostasisGO:0019725800.032
negative regulation of cytoskeleton organizationGO:0051494300.032
autophagyGO:00069141080.032
skeletal muscle fiber developmentGO:004874130.032
regulation of cellular localizationGO:00603411360.032
cellular protein localizationGO:00346131600.032
blood circulationGO:0008015260.031
heart contractionGO:0060047260.031
cellular macromolecular complex assemblyGO:00346221530.031
regulation of intracellular signal transductionGO:19025312360.031
response to endogenous stimulusGO:00097191190.031
locomotory behaviorGO:00076261760.030
negative regulation of actin filament depolymerizationGO:003083520.030
negative regulation of nitrogen compound metabolic processGO:00511722650.030
epithelium migrationGO:00901321480.030
phagocytosisGO:00069092150.030
positive regulation of gene expressionGO:00106282900.030
actin filament depolymerizationGO:003004250.030
metal ion homeostasisGO:0055065440.030
carbohydrate derivative catabolic processGO:19011361180.030
positive regulation of multicellular organismal processGO:00512401430.029
response to organic substanceGO:00100332840.029
regulation of apoptotic processGO:00429811300.029
dendrite morphogenesisGO:00488131990.029
eye developmentGO:00016543230.029
epithelial cell developmentGO:00020642740.029
purine nucleoside triphosphate metabolic processGO:00091441190.029
cellular response to oxygen containing compoundGO:1901701790.028
actin filament cappingGO:005169320.028
positive regulation of transcription dna templatedGO:00458932660.028
negative regulation of transcription dna templatedGO:00458922370.028
positive regulation of phosphorus metabolic processGO:00105621390.028
cellular macromolecule localizationGO:00707272200.028
actin filament based processGO:00300292200.028
positive regulation of cell communicationGO:00106472500.028
regulation of catalytic activityGO:00507901850.027
larval developmentGO:00021641040.027
regulation of response to oxidative stressGO:190288240.027
microtubule organizing center organizationGO:00310231680.027
membrane organizationGO:00610241120.027
purine ribonucleoside triphosphate catabolic processGO:00092071080.027
defense response to bacteriumGO:00427421780.026
imaginal disc derived appendage morphogenesisGO:00351143950.026
columnar cuboidal epithelial cell developmentGO:00020662490.026
immune system processGO:00023763470.026
tissue migrationGO:00901301550.026
cellular response to starvationGO:0009267610.026
myotube cell developmentGO:001490430.025
cytoplasmic transportGO:00164821300.025
reactive oxygen species metabolic processGO:0072593220.025
chemotaxisGO:00069352490.025
deathGO:00162652840.025
single organism intracellular transportGO:19025822070.025
protein polymerizationGO:0051258420.025
cellular protein complex assemblyGO:0043623710.025
positive regulation of mitochondrion organizationGO:001082280.025
muscle organ developmentGO:00075171270.024
regulation of protein modification processGO:00313991120.024
purine ribonucleotide catabolic processGO:00091541090.024
guanosine containing compound catabolic processGO:1901069740.024
localization of cellGO:00516742570.024
regulation of transportGO:00510491810.024
negative regulation of macromolecule biosynthetic processGO:00105582700.024
cellular amino acid metabolic processGO:0006520610.024
growthGO:00400073590.024
regionalizationGO:00030024160.024
negative regulation of response to stimulusGO:00485852580.023
organic acid metabolic processGO:00060821030.023
positive regulation of dendrite morphogenesisGO:005077590.023
somatic muscle developmentGO:0007525660.023
regulation of multicellular organismal developmentGO:20000264140.023
skeletal muscle organ developmentGO:0060538480.023
nucleotide catabolic processGO:00091661090.023
secretionGO:00469031090.023
sensory perceptionGO:00076001960.023
response to oxygen containing compoundGO:19017002000.023
morphogenesis of an epitheliumGO:00020092760.023
positive regulation of transportGO:0051050920.023
organophosphate metabolic processGO:00196371950.023
carboxylic acid metabolic processGO:0019752920.023
cellular chemical homeostasisGO:0055082400.022
positive regulation of rna metabolic processGO:00512542710.022
cell divisionGO:00513012480.022
organic substance catabolic processGO:19015753080.022
muscle contractionGO:0006936130.022
negative regulation of rna biosynthetic processGO:19026792400.022
ribonucleoside catabolic processGO:00424541120.022
nucleoside metabolic processGO:00091161270.022
regulation of phosphorus metabolic processGO:00511742100.022
regulation of phosphate metabolic processGO:00192202100.022
positive regulation of actin filament polymerizationGO:0030838110.022
nucleoside triphosphate metabolic processGO:00091411200.022
cellular response to chemical stimulusGO:00708871990.021
purine nucleoside triphosphate catabolic processGO:00091461080.021
microtubule based transportGO:0010970420.021
cellular catabolic processGO:00442483720.021
regulation of protein polymerizationGO:0032271280.021
regulation of cell cycleGO:00517262910.021
protein depolymerizationGO:0051261310.021
cellular ion homeostasisGO:0006873390.021
regulation of innate immune responseGO:0045088710.021
positive regulation of cellular catabolic processGO:0031331950.021
defense response to gram negative bacteriumGO:0050829940.021
cellular response to dna damage stimulusGO:00069742230.020
cation transportGO:00068121100.020
cellular response to sterol depletionGO:007150130.020
purine nucleotide catabolic processGO:00061951090.020
nuclear migrationGO:0007097200.020
regulation of anatomical structure morphogenesisGO:00226032420.020
cellular cation homeostasisGO:0030003380.020
transition metal ion homeostasisGO:0055076170.020
organophosphate catabolic processGO:00464341120.020
positive regulation of cellular protein metabolic processGO:00322701180.020
cell projection assemblyGO:0030031940.020
ribonucleoside metabolic processGO:00091191270.020
body morphogenesisGO:001017120.020
g2 dna damage checkpointGO:0031572690.019
phosphorylationGO:00163102940.019
multi organism reproductive behaviorGO:00447051210.019
nucleoside catabolic processGO:00091641120.019
regulation of molecular functionGO:00650092170.019
circulatory system processGO:0003013370.019
regulation of catabolic processGO:00098941700.019
post embryonic appendage morphogenesisGO:00351203850.019
response to radiationGO:00093141550.019
regulation of dendrite morphogenesisGO:0048814280.019
regulation of cytoskeleton organizationGO:0051493890.019
negative regulation of nucleobase containing compound metabolic processGO:00459342610.019
response to organonitrogen compoundGO:0010243750.019
regulation of pole plasm oskar mrna localizationGO:0007317270.019
cellular response to organic substanceGO:00713101320.019
positive regulation of intracellular signal transductionGO:19025331160.019
oocyte constructionGO:00073081120.019
dna metabolic processGO:00062592270.019
regulation of actin polymerization or depolymerizationGO:0008064270.019
glycosyl compound metabolic processGO:19016571270.019
ion homeostasisGO:0050801550.019
heterocycle catabolic processGO:00467001660.018
golgi vesicle transportGO:0048193270.018
muscle thin filament assemblyGO:007168950.018
spermatogenesisGO:00072832000.018
neurological system processGO:00508773580.018
response to oxygen radicalGO:000030530.018
organic cyclic compound catabolic processGO:19013611680.018
regulation of actin filament based processGO:0032970420.018
regulation of actin filament polymerizationGO:0030833250.018
immune responseGO:00069552460.018
cellular response to nutrient levelsGO:0031669620.018
positive regulation of cell deathGO:0010942690.018
purine ribonucleoside metabolic processGO:00461281270.018
meiotic nuclear divisionGO:00071261510.018
regulation of autophagyGO:0010506620.018
regulation of cellular protein metabolic processGO:00322682430.018
ribonucleoside triphosphate metabolic processGO:00091991190.018
regulation of cell substrate adhesionGO:001081020.018
oocyte axis specificationGO:00073091080.018
cytoskeleton dependent intracellular transportGO:0030705440.018
ribonucleoside triphosphate catabolic processGO:00092031080.018
regulation of cell cycle processGO:00105641810.017
regulation of protein depolymerizationGO:1901879270.017
positive regulation of cellular component biogenesisGO:0044089800.017
myotube differentiationGO:0014902460.017
eye morphogenesisGO:00485922600.017
regulation of i kappab kinase nf kappab signalingGO:004312220.017
divalent inorganic cation homeostasisGO:0072507290.017
positive regulation of cell developmentGO:0010720610.017
carbohydrate derivative metabolic processGO:19011352170.017
regulation of intracellular transportGO:0032386640.017
regulation of cell developmentGO:00602842150.017
regulation of immune system processGO:00026821760.017
regulation of heart contractionGO:0008016210.017
regulation of response to nutrient levelsGO:0032107180.017
centrosome organizationGO:00512971630.017
neuron projection guidanceGO:00974852410.017
reproductive behaviorGO:00190981220.017
transition metal ion transportGO:0000041160.016
mitotic nuclear divisionGO:00070672130.016
purine nucleoside metabolic processGO:00422781270.016
rna localizationGO:00064031150.016
multi multicellular organism processGO:00447061230.016
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.016
negative regulation of cellular response to oxidative stressGO:190040810.016
negative regulation of programmed cell deathGO:0043069720.016
regulation of response to extracellular stimulusGO:0032104180.016
ribonucleotide catabolic processGO:00092611090.016
dendrite developmentGO:00163582040.016
negative regulation of response to oxidative stressGO:190288310.016
spindle elongationGO:0051231830.016
homeostatic processGO:00425921990.016
oocyte microtubule cytoskeleton polarizationGO:0008103220.016
ameboidal type cell migrationGO:00016671510.016
positive regulation of catabolic processGO:00098961050.016
regulation of mitochondrial fusionGO:001063550.016
proteolysisGO:00065081920.016
zinc ion homeostasisGO:005506960.016
regulation of immune responseGO:00507761180.016
purine ribonucleoside catabolic processGO:00461301120.015
maintenance of locationGO:0051235730.015
regulation of nervous system developmentGO:00519602480.015
organonitrogen compound catabolic processGO:19015651280.015
regulation of mitotic cell cycleGO:00073461900.015
mitochondrion organizationGO:0007005650.015
glycosyl compound catabolic processGO:19016581120.015
neuron recognitionGO:00080381010.015
biological adhesionGO:00226101380.015
negative regulation of protein depolymerizationGO:1901880230.015
response to light stimulusGO:00094161240.015
cytoskeleton dependent cytokinesisGO:0061640810.015
ribonucleotide metabolic processGO:00092591450.015
regulation of cell differentiationGO:00455953020.015
chromosome segregationGO:00070591570.015
positive regulation of catalytic activityGO:00430851180.015
response to temperature stimulusGO:00092661060.015
macroautophagyGO:0016236420.015
regulation of mitochondrion organizationGO:0010821120.015
nucleoside phosphate catabolic processGO:19012921100.014
cation homeostasisGO:0055080510.014
enzyme linked receptor protein signaling pathwayGO:00071671790.014
appendage morphogenesisGO:00351073970.014
negative regulation of rna metabolic processGO:00512532510.014
response to woundingGO:0009611940.014
tissue deathGO:00162711020.014
humoral immune responseGO:00069591170.014
nucleobase containing small molecule metabolic processGO:00550861740.014
aromatic compound catabolic processGO:00194391660.014
embryonic axis specificationGO:00005781070.014
positive regulation of cell migrationGO:003033520.014
establishment of nucleus localizationGO:0040023260.014
regulation of protein complex assemblyGO:0043254420.014
nucleoside phosphate metabolic processGO:00067531620.014
negative regulation of biosynthetic processGO:00098902770.014
male gamete generationGO:00482322010.014
cellular response to decreased oxygen levelsGO:0036294300.014
response to extracellular stimulusGO:00099911160.014
positive regulation of programmed cell deathGO:0043068620.014
regulation of nurse cell apoptotic processGO:004547790.014
spindle organizationGO:00070512530.014
single organism biosynthetic processGO:00447112060.014
purine containing compound metabolic processGO:00725211550.014
synaptic transmission dopaminergicGO:000196320.014
single organism nuclear importGO:1902593510.014
cell adhesionGO:00071551360.013
spermatid developmentGO:0007286980.013
sensory perception of mechanical stimulusGO:0050954720.013
response to nitrogen compoundGO:1901698900.013
single organism behaviorGO:00447083910.013
positive regulation of filopodium assemblyGO:0051491150.013
nucleotide metabolic processGO:00091171610.013
cellular nitrogen compound catabolic processGO:00442701650.013
positive regulation of nucleic acid templated transcriptionGO:19035082660.013
imaginal disc derived wing morphogenesisGO:00074763370.013
meiotic cell cycle processGO:19030461320.013
actin filament organizationGO:00070151260.013
nuclear importGO:0051170510.013
muscle attachmentGO:0016203360.013
mitotic spindle elongationGO:0000022810.013
cation transmembrane transportGO:0098655880.013
positive regulation of phosphate metabolic processGO:00459371390.013
open tracheal system developmentGO:00074242040.013
nucleus localizationGO:0051647340.013
positive regulation of purine nucleotide catabolic processGO:0033123460.013
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stressGO:007005940.013
antimicrobial humoral responseGO:0019730990.013
organelle localizationGO:00516401480.013
regulation of phosphorylationGO:00423251470.012
regulation of protein metabolic processGO:00512462560.012
er nucleus signaling pathwayGO:000698490.012
response to oxidative stressGO:0006979860.012
rac protein signal transductionGO:001660130.012
single organismal cell cell adhesionGO:0016337450.012
ion transportGO:00068111450.012
ribose phosphate metabolic processGO:00196931450.012
extracellular structure organizationGO:0043062460.012
neuron maturationGO:0042551310.012
neuronal action potentialGO:0019228100.012
intracellular protein transportGO:00068861040.012
axonogenesisGO:00074092900.012
positive regulation of intracellular transportGO:0032388420.012
microtubule based movementGO:0007018510.012
positive regulation of protein modification processGO:0031401580.012
regulation of cell sizeGO:0008361630.012
mitotic spindle organizationGO:00070522200.012
positive regulation of protein transportGO:0051222370.012
taxisGO:00423303040.012
regulation of tor signalingGO:0032006210.012
regulation of cell matrix adhesionGO:000195210.012
male meiosis cytokinesisGO:0007112260.012
response to organophosphorusGO:004668320.012
modification dependent protein catabolic processGO:0019941780.012
nucleoside triphosphate catabolic processGO:00091431080.012
regulation of cellular ketone metabolic processGO:001056530.012
positive regulation of nucleotide metabolic processGO:0045981550.012
sensory organ morphogenesisGO:00905962600.012
early endosome to late endosome transportGO:004502230.011
purine nucleoside catabolic processGO:00061521120.011
female germ line cyst formationGO:0048135420.011
actin polymerization or depolymerizationGO:0008154310.011
nucleobase containing compound catabolic processGO:00346551650.011
establishment or maintenance of cell polarityGO:00071631670.011
protein secretionGO:0009306450.011
mitotic g2 m transition checkpointGO:0044818700.011
epithelial cell migrationGO:00106311480.011
macromolecular complex disassemblyGO:0032984370.011
chromatin organizationGO:00063252070.011
response to endoplasmic reticulum stressGO:0034976280.011
positive regulation of molecular functionGO:00440931360.011
nuclear transportGO:0051169720.011
nucleocytoplasmic transportGO:0006913720.011
embryonic morphogenesisGO:00485982060.011
mapk cascadeGO:00001651070.011
purine nucleotide metabolic processGO:00061631460.011
negative regulation of apoptotic processGO:0043066630.011
nucleobase containing compound transportGO:0015931560.011
compound eye developmentGO:00487493070.011
regulation of hydrolase activityGO:0051336970.011
wound healingGO:0042060750.011
regulation of establishment of protein localizationGO:0070201610.011
negative regulation of mitotic cell cycleGO:00459301090.011
regulation of vesicle mediated transportGO:0060627590.011
imaginal disc derived appendage developmentGO:00487373990.011
regulation of reactive oxygen species metabolic processGO:200037780.010
regulation of cell morphogenesis involved in differentiationGO:0010769610.010
response to starvationGO:0042594970.010
positive regulation of developmental growthGO:0048639620.010
cell recognitionGO:00080371020.010
positive regulation of organelle organizationGO:0010638650.010
cell type specific apoptotic processGO:0097285380.010
response to calcium ionGO:005159210.010
microtubule polymerization or depolymerizationGO:0031109390.010
response to alcoholGO:0097305950.010
protein heterooligomerizationGO:005129140.010
positive regulation of cell motilityGO:200014730.010
positive regulation of apoptotic processGO:0043065470.010
negative regulation of protein complex disassemblyGO:0043242230.010
anterior posterior pattern specificationGO:00099521360.010
cuticle pigmentationGO:0048067220.010

Tom34 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.064
nervous system diseaseDOID:86300.058
cardiovascular system diseaseDOID:128700.039
musculoskeletal system diseaseDOID:1700.024
muscle tissue diseaseDOID:6600.024
muscular diseaseDOID:008000000.024
neuromuscular diseaseDOID:44000.015
neuropathyDOID:87000.015
central nervous system diseaseDOID:33100.015
myopathyDOID:42300.014
neurodegenerative diseaseDOID:128900.013
heart diseaseDOID:11400.013
cardiomyopathyDOID:005070000.013
intrinsic cardiomyopathyDOID:006003600.013
sensory system diseaseDOID:005015500.012
dilated cardiomyopathyDOID:1293000.011
eye and adnexa diseaseDOID:149200.011
cancerDOID:16200.010
disease of cellular proliferationDOID:1456600.010
organ system cancerDOID:005068600.010
motor neuron diseaseDOID:23100.010