Drosophila melanogaster

132 known processes

Bub1 (Dmel_CG14030)

Bub1 homologue

(Aliases: BUB1,BubRI,CG14030,BubR1,BUB1-like,Dmel\CG14030,CG14030/Bub1,bub1)

Bub1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of gene expression epigeneticGO:00400291280.193
protein modification processGO:00362114380.158
positive regulation of nitrogen compound metabolic processGO:00511733540.144
transcription from rna polymerase ii promoterGO:00063663680.118
negative regulation of signalingGO:00230572190.113
negative regulation of cellular metabolic processGO:00313243820.107
macromolecular complex assemblyGO:00650032560.096
negative regulation of rna metabolic processGO:00512532510.080
protein complex assemblyGO:00064612000.078
regulation of intracellular signal transductionGO:19025312360.074
Mouse
regulation of programmed cell deathGO:00430671520.071
Mouse
apoptotic processGO:00069151590.069
Mouse Worm
growthGO:00400073590.063
regulation of transcription from rna polymerase ii promoterGO:00063573780.062
single organism behaviorGO:00447083910.059
negative regulation of signal transductionGO:00099682060.057
neurological system processGO:00508773580.053
chromatin modificationGO:00165681470.051
regulation of cellular ketone metabolic processGO:001056530.050
protein catabolic processGO:00301631010.047
positive regulation of cellular component organizationGO:00511301560.047
regulation of localizationGO:00328792750.044
regulation of ras protein signal transductionGO:0046578930.044
positive regulation of multicellular organismal processGO:00512401430.042
regulation of cellular localizationGO:00603411360.042
oxoacid metabolic processGO:00434361030.042
chromatin silencingGO:0006342760.041
negative regulation of macromolecule biosynthetic processGO:00105582700.040
positive regulation of developmental processGO:00510941430.040
regulation of cell differentiationGO:00455953020.039
positive regulation of cell deathGO:0010942690.039
Mouse
regulation of protein localizationGO:0032880760.039
cell deathGO:00082192790.039
Mouse Worm
morphogenesis of an epitheliumGO:00020092760.039
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.038
negative regulation of nucleic acid templated transcriptionGO:19035072400.038
cellular protein modification processGO:00064644380.037
regulation of cellular amino acid metabolic processGO:000652100.037
regulation of protein transportGO:0051223570.037
positive regulation of biosynthetic processGO:00098913160.037
regulation of cellular amine metabolic processGO:003323830.037
ras protein signal transductionGO:0007265880.036
regulation of neuron differentiationGO:00456641030.036
regulation of multicellular organismal developmentGO:20000264140.035
gene silencingGO:00164581380.034
homeostatic processGO:00425921990.034
positive regulation of proteolysisGO:0045862520.033
positive regulation of nucleobase containing compound metabolic processGO:00459353320.033
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.033
regulation of cell deathGO:00109411730.033
Mouse
larval developmentGO:00021641040.032
Worm
positive regulation of cell communicationGO:00106472500.032
Mouse
positive regulation of cellular amine metabolic processGO:003324000.032
localization of cellGO:00516742570.031
sensory organ morphogenesisGO:00905962600.030
programmed cell deathGO:00125012570.030
Mouse Worm
single organism catabolic processGO:00447122280.029
zymogen activationGO:0031638200.028
lipid metabolic processGO:00066291210.028
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.028
single organism biosynthetic processGO:00447112060.028
response to abiotic stimulusGO:00096283410.027
regulation of establishment of protein localizationGO:0070201610.027
intracellular signal transductionGO:00355563000.027
Mouse
carboxylic acid metabolic processGO:0019752920.026
cellular amine metabolic processGO:0044106120.026
negative regulation of cellular protein metabolic processGO:0032269850.026
protein complex biogenesisGO:00702712010.026
organonitrogen compound metabolic processGO:19015643180.025
positive regulation of signalingGO:00230562430.025
Mouse
organic substance catabolic processGO:19015753080.025
histone modificationGO:00165701060.024
tissue morphogenesisGO:00487292970.024
embryo development ending in birth or egg hatchingGO:00097921520.024
Worm
negative regulation of nucleobase containing compound metabolic processGO:00459342610.024
regulation of phosphate metabolic processGO:00192202100.024
organonitrogen compound biosynthetic processGO:19015661170.024
regulation of molecular functionGO:00650092170.023
cellular amino acid metabolic processGO:0006520610.023
positive regulation of programmed cell deathGO:0043068620.023
Mouse
negative regulation of nitrogen compound metabolic processGO:00511722650.023
negative regulation of gene expression epigeneticGO:0045814770.023
peptidyl lysine modificationGO:0018205570.023
signal transduction by phosphorylationGO:00230141070.023
regulation of proteolysisGO:0030162870.022
amine metabolic processGO:0009308120.022
cognitionGO:00508901410.022
dna metabolic processGO:00062592270.022
body morphogenesisGO:001017120.021
regulation of cellular component biogenesisGO:00440872010.021
regulation of mapk cascadeGO:0043408920.021
negative regulation of developmental processGO:00510932010.021
actin filament based processGO:00300292200.021
mapk cascadeGO:00001651070.020
regulation of protein complex assemblyGO:0043254420.020
cellular ketone metabolic processGO:0042180240.020
small molecule metabolic processGO:00442813050.020
regulation of protein metabolic processGO:00512462560.020
chromatin organizationGO:00063252070.020
negative regulation of cellular biosynthetic processGO:00313272770.020
small gtpase mediated signal transductionGO:0007264880.020
peptidyl amino acid modificationGO:00181931050.020
macromolecule catabolic processGO:00090571610.019
organic acid metabolic processGO:00060821030.019
maintenance of protein location in cellGO:0032507260.019
appendage developmentGO:00487364010.019
regionalizationGO:00030024160.019
protein phosphorylationGO:00064681690.019
regulation of transportGO:00510491810.019
compound eye photoreceptor cell differentiationGO:00017511400.019
segmentationGO:00352822070.019
humoral immune responseGO:00069591170.018
response to biotic stimulusGO:00096072940.018
positive regulation of phosphorus metabolic processGO:00105621390.018
chromatin remodelingGO:0006338720.018
defense response to other organismGO:00985422250.018
mitotic nuclear divisionGO:00070672130.018
negative regulation of cell communicationGO:00106482230.018
negative regulation of response to stimulusGO:00485852580.018
posttranscriptional gene silencingGO:0016441460.018
ubiquitin dependent protein catabolic processGO:0006511780.018
regulation of multi organism processGO:00439001310.017
axon developmentGO:00615642970.017
negative regulation of multicellular organismal processGO:00512411420.017
regulation of cell developmentGO:00602842150.017
learning or memoryGO:00076111410.017
enzyme linked receptor protein signaling pathwayGO:00071671790.017
response to other organismGO:00517072930.017
protein modification by small protein conjugation or removalGO:00706471060.017
catabolic processGO:00090564090.017
embryonic pattern specificationGO:00098801740.017
positive regulation of nucleic acid templated transcriptionGO:19035082660.017
positive regulation of response to stimulusGO:00485843230.016
Mouse
regulation of gene silencingGO:0060968630.016
cellular macromolecule catabolic processGO:00442651360.016
eye photoreceptor cell differentiationGO:00017541450.016
positive regulation of gene expressionGO:00106282900.016
camera type eye developmentGO:004301040.016
anterior posterior pattern specificationGO:00099521360.016
nuclear divisionGO:00002803320.016
regulation of nervous system developmentGO:00519602480.016
mitotic g2 m transition checkpointGO:0044818700.016
response to endogenous stimulusGO:00097191190.015
cellular macromolecule localizationGO:00707272200.015
immune system processGO:00023763470.015
blastoderm segmentationGO:00073501590.015
response to external biotic stimulusGO:00432072930.015
protein maturationGO:0051604710.015
defense responseGO:00069523000.015
hematopoietic or lymphoid organ developmentGO:0048534570.015
regulation of phosphorus metabolic processGO:00511742100.015
phagocytosisGO:00069092150.015
maintenance of location in cellGO:0051651280.015
axis specificationGO:00097981670.015
locomotor rhythmGO:0045475560.015
central nervous system developmentGO:00074172010.015
regulation of organelle organizationGO:00330431960.015
endocytosisGO:00068973100.015
immune responseGO:00069552460.015
protein localizationGO:00081042840.015
positive regulation of organelle organizationGO:0010638650.015
positive regulation of cell migrationGO:003033520.015
chemical homeostasisGO:0048878920.014
establishment of localization in cellGO:00516494020.014
muscle system processGO:0003012210.014
nucleus organizationGO:0006997450.014
camera type eye morphogenesisGO:004859320.014
negative regulation of erk1 and erk2 cascadeGO:007037330.014
protein acylationGO:0043543420.014
regulation of growthGO:00400082330.014
organic cyclic compound catabolic processGO:19013611680.014
microtubule organizing center organizationGO:00310231680.014
deathGO:00162652840.014
Mouse Worm
response to oxygen containing compoundGO:19017002000.014
negative regulation of biosynthetic processGO:00098902770.014
positive regulation of apoptotic signaling pathwayGO:200123540.013
Mouse
response to organic substanceGO:00100332840.013
protein ubiquitinationGO:0016567700.013
negative regulation of protein metabolic processGO:0051248850.013
amide biosynthetic processGO:0043604420.013
negative regulation of ras protein signal transductionGO:0046580130.013
protein transportGO:00150311550.013
respiratory system developmentGO:00605412130.013
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919160.013
positive regulation of rna metabolic processGO:00512542710.013
posttranscriptional gene silencing by rnaGO:0035194450.013
negative regulation of cell differentiationGO:00455961430.013
rna processingGO:00063961470.013
regulation of small gtpase mediated signal transductionGO:0051056930.013
activation of cysteine type endopeptidase activityGO:0097202170.013
chromosome organizationGO:00512763600.013
regulation of cell substrate adhesionGO:001081020.012
phosphorylationGO:00163102940.012
covalent chromatin modificationGO:00165691060.012
photoreceptor cell differentiationGO:00465301700.012
erk1 and erk2 cascadeGO:0070371390.012
cell proliferationGO:00082832990.012
Rat
regulation of epithelial cell proliferationGO:005067840.012
negative regulation of rna biosynthetic processGO:19026792400.012
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.012
modification dependent macromolecule catabolic processGO:0043632790.012
positive regulation of phosphate metabolic processGO:00459371390.012
dorsal ventral axis specificationGO:0009950660.012
mrna metabolic processGO:00160711240.012
positive regulation of cellular amino acid metabolic processGO:004576400.012
proteasomal protein catabolic processGO:0010498590.012
proteolysisGO:00065081920.012
positive regulation of cellular biosynthetic processGO:00313283160.012
cell motilityGO:00488702510.012
positive regulation of rna biosynthetic processGO:19026802660.012
actin cytoskeleton organizationGO:00300362060.012
regulation of mitotic cell cycleGO:00073461900.012
locomotory behaviorGO:00076261760.012
positive regulation of cell differentiationGO:0045597640.012
heart developmentGO:0007507820.011
kidney developmentGO:000182230.011
cell migrationGO:00164772380.011
cellular macromolecular complex assemblyGO:00346221530.011
protein alkylationGO:0008213430.011
nucleoside triphosphate metabolic processGO:00091411200.011
dorsal ventral pattern formationGO:00099531330.011
intracellular transportGO:00469072280.011
organelle assemblyGO:00709251980.011
regulation of cell proliferationGO:00421271630.011
regulation of phosphorylationGO:00423251470.011
response to alcoholGO:0097305950.011
organonitrogen compound catabolic processGO:19015651280.011
retina development in camera type eyeGO:006004140.011
purine ribonucleotide catabolic processGO:00091541090.011
defense response to bacteriumGO:00427421780.011
positive regulation of protein metabolic processGO:00512471280.011
cell agingGO:000756920.011
regulation of protein catabolic processGO:0042176550.011
regulation of immune system processGO:00026821760.011
peptide biosynthetic processGO:0043043420.011
developmental maturationGO:00217001720.011
positive regulation of transcription dna templatedGO:00458932660.011
positive regulation of protein complex assemblyGO:0031334220.010
regulation of cytoskeleton organizationGO:0051493890.010
organophosphate metabolic processGO:00196371950.010
immune effector processGO:0002252980.010
nucleoside triphosphate catabolic processGO:00091431080.010
hematopoietic progenitor cell differentiationGO:000224410.010
heterocycle catabolic processGO:00467001660.010
nucleotide metabolic processGO:00091171610.010
negative regulation of cell deathGO:0060548810.010
open tracheal system developmentGO:00074242040.010
positive regulation of mapk cascadeGO:0043410630.010
purine nucleotide metabolic processGO:00061631460.010

Bub1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.016
sensory system diseaseDOID:005015500.016
eye and adnexa diseaseDOID:149200.016
nervous system diseaseDOID:86300.016
disease of cellular proliferationDOID:1456600.013
organ system cancerDOID:005068600.013
cancerDOID:16200.013
eye diseaseDOID:561400.012