IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

Cyp4ac1 (Dmel_CG14032)

CG14032 gene product from transcript CG14032-RA

(Aliases: 4ac1,Dmel\CG14032,CG14032)

FLYBASE: FBgn0031693
Entrez: 33754
UniProtKB: Q9VMS9

Process Predictions
Disease Predictions

Cyp4ac1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
insecticide metabolic process	GO:0017143	2	0.982
medium chain fatty acid metabolic process	GO:0051791	1	0.975
steroid catabolic process	GO:0006706	1	0.830
secondary metabolite catabolic process	GO:0090487	1	0.815
multi organism behavior	GO:0051705	175	0.658
insecticide catabolic process	GO:0046701	1	0.596
response to mercury ion	GO:0046689	3	0.573
fat soluble vitamin metabolic process	GO:0006775	1	0.549
toxin metabolic process	GO:0009404	2	0.512
lauric acid metabolic process	GO:0048252	1	0.473
cellular catabolic process	GO:0044248	372	0.447
response to ddt	GO:0046680	5	0.442
anion homeostasis	GO:0055081	3	0.409
xenobiotic catabolic process	GO:0042178	1	0.408
polyol biosynthetic process	GO:0046173	3	0.385
response to insecticide	GO:0017085	14	0.364
secondary metabolic process	GO:0019748	75	0.362
epithelial cell development	GO:0002064	274	0.298
mating	GO:0007618	120	0.294	Fly
neurotransmitter catabolic process	GO:0042135	1	0.260
ketone biosynthetic process	GO:0042181	16	0.254
vitamin biosynthetic process	GO:0009110	1	0.251
organonitrogen compound catabolic process	GO:1901565	128	0.234
organonitrogen compound metabolic process	GO:1901564	318	0.221
male gamete generation	GO:0048232	201	0.216
lipid catabolic process	GO:0016042	21	0.215
ecdysteroid biosynthetic process	GO:0045456	15	0.208
regulation of tube size	GO:0035150	46	0.204
single organism catabolic process	GO:0044712	228	0.202
cellular hormone metabolic process	GO:0034754	23	0.197
organic hydroxy compound biosynthetic process	GO:1901617	21	0.195
response to toxic substance	GO:0009636	22	0.194
response to biotic stimulus	GO:0009607	294	0.185
response to other organism	GO:0051707	293	0.173
epithelial cell migration	GO:0010631	148	0.172
epithelial cell differentiation	GO:0030855	322	0.170
organic hydroxy compound metabolic process	GO:1901615	83	0.170
alcohol biosynthetic process	GO:0046165	14	0.167
hormone catabolic process	GO:0042447	3	0.166
hormone metabolic process	GO:0042445	33	0.158
steroid metabolic process	GO:0008202	20	0.155
ovarian follicle cell development	GO:0030707	248	0.149
response to bacterium	GO:0009617	198	0.149
response to caffeine	GO:0031000	12	0.149
ethanolamine containing compound metabolic process	GO:0042439	4	0.148
sterol biosynthetic process	GO:0016126	9	0.147
small molecule biosynthetic process	GO:0044283	37	0.147
growth	GO:0040007	359	0.144
steroid biosynthetic process	GO:0006694	16	0.140
lipid metabolic process	GO:0006629	121	0.139	Fly
positive regulation of gene expression	GO:0010628	290	0.139
response to organophosphorus	GO:0046683	2	0.138
response to external biotic stimulus	GO:0043207	293	0.135
developmental growth	GO:0048589	280	0.134
small molecule metabolic process	GO:0044281	305	0.131
sensory perception of smell	GO:0007608	80	0.125
regulation of growth	GO:0040008	233	0.122
reproductive behavior	GO:0019098	122	0.120
neurological system process	GO:0050877	358	0.118
cellular ketone metabolic process	GO:0042180	24	0.117
ovarian follicle cell migration	GO:0007297	121	0.115
hormone biosynthetic process	GO:0042446	20	0.115
response to xenobiotic stimulus	GO:0009410	5	0.111
regulation of anatomical structure size	GO:0090066	163	0.111
imaginal disc derived appendage development	GO:0048737	399	0.109
border follicle cell migration	GO:0007298	113	0.108
multi multicellular organism process	GO:0044706	123	0.108
sensory perception of chemical stimulus	GO:0007606	116	0.107
catabolic process	GO:0009056	409	0.107
cellular nitrogen compound catabolic process	GO:0044270	165	0.107
tissue migration	GO:0090130	155	0.101
organic cyclic compound catabolic process	GO:1901361	168	0.099
columnar cuboidal epithelial cell development	GO:0002066	249	0.099
regulation of hormone levels	GO:0010817	40	0.098
regulation of developmental growth	GO:0048638	174	0.097
multicellular organismal reproductive behavior	GO:0033057	110	0.097
ecdysone biosynthetic process	GO:0006697	9	0.097
aggressive behavior	GO:0002118	63	0.095
ecdysteroid metabolic process	GO:0045455	19	0.094
dorsal closure	GO:0007391	79	0.091
spermatogenesis	GO:0007283	200	0.090
chemical homeostasis	GO:0048878	92	0.090
acetylcholine metabolic process	GO:0008291	2	0.090
single organism behavior	GO:0044708	391	0.089
multi organism reproductive behavior	GO:0044705	121	0.088
organic acid metabolic process	GO:0006082	103	0.088
tergite morphogenesis	GO:0007490	1	0.086
ecdysone metabolic process	GO:0008205	11	0.084
response to organic substance	GO:0010033	284	0.080
response to abiotic stimulus	GO:0009628	341	0.076
mating behavior	GO:0007617	106	0.076
wing disc morphogenesis	GO:0007472	344	0.076
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.075
imaginal disc derived wing morphogenesis	GO:0007476	337	0.075
organic substance catabolic process	GO:1901575	308	0.075
amine metabolic process	GO:0009308	12	0.072
toxin catabolic process	GO:0009407	1	0.071
cellular lipid metabolic process	GO:0044255	83	0.071
choline metabolic process	GO:0019695	1	0.069
positive regulation of macromolecule metabolic process	GO:0010604	405	0.068
sensory organ morphogenesis	GO:0090596	260	0.068
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.064
lipid biosynthetic process	GO:0008610	46	0.063
sterol metabolic process	GO:0016125	12	0.063
acetate ester metabolic process	GO:1900619	2	0.061
post embryonic appendage morphogenesis	GO:0035120	385	0.059
terpenoid metabolic process	GO:0006721	7	0.058
vitamin metabolic process	GO:0006766	2	0.058
cellular amine metabolic process	GO:0044106	12	0.057
response to purine containing compound	GO:0014074	12	0.057
carboxylic acid metabolic process	GO:0019752	92	0.057
monocarboxylic acid metabolic process	GO:0032787	29	0.057
ameboidal type cell migration	GO:0001667	151	0.056
compound eye morphogenesis	GO:0001745	249	0.056
response to organic cyclic compound	GO:0014070	89	0.056
regulation of blood circulation	GO:1903522	21	0.055
response to organonitrogen compound	GO:0010243	75	0.055
proteolysis	GO:0006508	192	0.055
eye development	GO:0001654	323	0.055
defense response to gram negative bacterium	GO:0050829	94	0.053
fat soluble vitamin biosynthetic process	GO:0042362	1	0.053
sensory perception	GO:0007600	196	0.052
alcohol metabolic process	GO:0006066	25	0.052
single organism biosynthetic process	GO:0044711	206	0.052
defense response to other organism	GO:0098542	225	0.051
response to nitrogen compound	GO:1901698	90	0.050
cellular chemical homeostasis	GO:0055082	40	0.049
eye morphogenesis	GO:0048592	260	0.048
morphogenesis of an epithelium	GO:0002009	276	0.048
androgen metabolic process	GO:0008209	1	0.048
appendage development	GO:0048736	401	0.047
regionalization	GO:0003002	416	0.047
chitin based embryonic cuticle biosynthetic process	GO:0008362	16	0.046
protein complex assembly	GO:0006461	200	0.045
aromatic compound catabolic process	GO:0019439	166	0.044
response to temperature stimulus	GO:0009266	106	0.044
cell motility	GO:0048870	251	0.043
positive regulation of multicellular organismal process	GO:0051240	143	0.043
heterocycle catabolic process	GO:0046700	166	0.043
cuticle development	GO:0042335	86	0.043
response to ethanol	GO:0045471	59	0.042
tissue morphogenesis	GO:0048729	297	0.042
monocarboxylic acid transport	GO:0015718	3	0.041
defense response to bacterium	GO:0042742	178	0.040
epithelium migration	GO:0090132	148	0.039
spermatid differentiation	GO:0048515	114	0.038
head involution	GO:0008258	35	0.037
neurotransmitter metabolic process	GO:0042133	2	0.036
protein modification process	GO:0036211	438	0.036
response to inorganic substance	GO:0010035	44	0.036
chromosome segregation	GO:0007059	157	0.036
respiratory system development	GO:0060541	213	0.036
cell migration	GO:0016477	238	0.035
acetylcholine catabolic process	GO:0006581	1	0.035
nuclear division	GO:0000280	332	0.034
localization of cell	GO:0051674	257	0.034
organelle fission	GO:0048285	340	0.034
response to alkaloid	GO:0043279	26	0.034
meiotic chromosome segregation	GO:0045132	59	0.033
response to nutrient levels	GO:0031667	114	0.033
defense response	GO:0006952	300	0.033
peripheral nervous system development	GO:0007422	52	0.033
response to lipopolysaccharide	GO:0032496	4	0.032
oxidation reduction process	GO:0055114	123	0.032
open tracheal system development	GO:0007424	204	0.032
compound eye development	GO:0048749	307	0.031
choline catabolic process	GO:0042426	1	0.031
heart development	GO:0007507	82	0.031
axonogenesis	GO:0007409	290	0.031
axon guidance	GO:0007411	233	0.030
digestive tract development	GO:0048565	149	0.029
ion homeostasis	GO:0050801	55	0.029
spermatid development	GO:0007286	98	0.029
kidney development	GO:0001822	3	0.029
synaptic transmission	GO:0007268	288	0.028
cellular protein modification process	GO:0006464	438	0.027
chemotaxis	GO:0006935	249	0.027
cellular ion homeostasis	GO:0006873	39	0.027
response to extracellular stimulus	GO:0009991	116	0.026
inter male aggressive behavior	GO:0002121	60	0.026
midgut development	GO:0007494	23	0.026
neuron projection guidance	GO:0097485	241	0.026
cellular response to chemical stimulus	GO:0070887	199	0.025
embryonic development via the syncytial blastoderm	GO:0001700	148	0.025
amine catabolic process	GO:0009310	1	0.025
axon development	GO:0061564	297	0.025
biological adhesion	GO:0022610	138	0.025
fatty acid metabolic process	GO:0006631	20	0.025
cell adhesion involved in heart morphogenesis	GO:0061343	12	0.024
cell proliferation	GO:0008283	299	0.024
positive regulation of response to stimulus	GO:0048584	323	0.024
homeostatic process	GO:0042592	199	0.023
chitin based cuticle development	GO:0040003	49	0.023
energy taxis	GO:0009453	21	0.023
organic substance transport	GO:0071702	257	0.022
neuron recognition	GO:0008038	101	0.022
carbohydrate derivative metabolic process	GO:1901135	217	0.022
appendage morphogenesis	GO:0035107	397	0.021
phagocytosis	GO:0006909	215	0.021
benzene containing compound metabolic process	GO:0042537	3	0.021
thermosensory behavior	GO:0040040	19	0.020
heart morphogenesis	GO:0003007	32	0.020
cell adhesion	GO:0007155	136	0.020
cellular response to ethanol	GO:0071361	4	0.020
regulation of neurotransmitter levels	GO:0001505	38	0.019
epidermis development	GO:0008544	65	0.019
meiotic cell cycle	GO:0051321	171	0.019
tube development	GO:0035295	244	0.019
regulation of tube size open tracheal system	GO:0035151	43	0.019
motor neuron axon guidance	GO:0008045	58	0.019
regulation of tube architecture open tracheal system	GO:0035152	68	0.019
oxoacid metabolic process	GO:0043436	103	0.019
macromolecular complex assembly	GO:0065003	256	0.019
chaeta development	GO:0022416	97	0.019
telencephalon development	GO:0021537	2	0.019
negative regulation of female receptivity	GO:0007621	14	0.018
regulation of localization	GO:0032879	275	0.018
regulation of sequestering of triglyceride	GO:0010889	3	0.018
response to metal ion	GO:0010038	23	0.018
gland development	GO:0048732	191	0.018
histoblast morphogenesis	GO:0007488	9	0.018
response to endogenous stimulus	GO:0009719	119	0.018
aging	GO:0007568	143	0.017
response to oxygen containing compound	GO:1901700	200	0.017
macromolecule catabolic process	GO:0009057	161	0.017
central nervous system development	GO:0007417	201	0.017
establishment of blood nerve barrier	GO:0008065	2	0.017
circulatory system process	GO:0003013	37	0.017
non sensory hair organization	GO:0035316	47	0.017
cellular response to ketone	GO:1901655	17	0.017
maintenance of location	GO:0051235	73	0.016
protein complex biogenesis	GO:0070271	201	0.016
carbohydrate derivative catabolic process	GO:1901136	118	0.016
female meiosis chromosome segregation	GO:0016321	33	0.016
regulation of system process	GO:0044057	36	0.016
cellular amino acid metabolic process	GO:0006520	61	0.016
female meiotic division	GO:0007143	70	0.016
cellularization	GO:0007349	90	0.016
apical junction assembly	GO:0043297	32	0.016
cellular biogenic amine catabolic process	GO:0042402	1	0.015
meiotic nuclear division	GO:0007126	151	0.015
lipid localization	GO:0010876	54	0.015
regulation of transport	GO:0051049	181	0.015
synaptic target recognition	GO:0008039	45	0.015
isoprenoid metabolic process	GO:0006720	8	0.015
chitin catabolic process	GO:0006032	3	0.015
female mating behavior	GO:0060180	30	0.015
embryonic morphogenesis	GO:0048598	206	0.015
negative chemotaxis	GO:0050919	15	0.015
lipid storage	GO:0019915	38	0.015
endocytosis	GO:0006897	310	0.014
mrna processing	GO:0006397	104	0.014
immune system process	GO:0002376	347	0.014
response to drug	GO:0042493	17	0.014
xenobiotic metabolic process	GO:0006805	5	0.014
regulation of female receptivity	GO:0045924	24	0.014
transcription from rna polymerase ii promoter	GO:0006366	368	0.014
maintenance of imaginal disc derived wing hair orientation	GO:0035321	3	0.014
hair cell differentiation	GO:0035315	47	0.014
glucosamine containing compound catabolic process	GO:1901072	3	0.013
cellular homeostasis	GO:0019725	80	0.013
multicellular organismal aging	GO:0010259	140	0.013
estrogen metabolic process	GO:0008210	1	0.013
response to lipid	GO:0033993	38	0.013
embryo development ending in birth or egg hatching	GO:0009792	152	0.013
response to alcohol	GO:0097305	95	0.013
phototaxis	GO:0042331	21	0.013
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.013
cellular response to organic substance	GO:0071310	132	0.012
digestive system development	GO:0055123	149	0.012
meiotic cell cycle process	GO:1903046	132	0.012
male mating behavior	GO:0060179	70	0.012
vesicle mediated transport	GO:0016192	381	0.012
regulation of cellular ketone metabolic process	GO:0010565	3	0.012
dorsal ventral pattern formation	GO:0009953	133	0.012
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.012
response to transition metal nanoparticle	GO:1990267	9	0.012
cell junction assembly	GO:0034329	42	0.012
pheromone biosynthetic process	GO:0042811	3	0.012
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.012
camera type eye development	GO:0043010	4	0.012
actin filament based process	GO:0030029	220	0.012
nucleus organization	GO:0006997	45	0.011
positive regulation of cell migration	GO:0030335	2	0.011
drinking behavior	GO:0042756	2	0.011
cardiovascular system development	GO:0072358	82	0.011
regulation of cell shape	GO:0008360	113	0.011
response to hormone	GO:0009725	45	0.011
aromatic amino acid family metabolic process	GO:0009072	3	0.011
amino sugar catabolic process	GO:0046348	3	0.011
ocellus pigment metabolic process	GO:0046158	19	0.011
positive regulation of cell motility	GO:2000147	3	0.010
mitotic nuclear division	GO:0007067	213	0.010
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.010
positive regulation of signal transduction	GO:0009967	223	0.010
secondary metabolite biosynthetic process	GO:0044550	24	0.010
regulation of immune system process	GO:0002682	176	0.010
skin development	GO:0043588	65	0.010
spindle organization	GO:0007051	253	0.010
ion transport	GO:0006811	145	0.010
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.010
forebrain development	GO:0030900	2	0.010
anion transport	GO:0006820	41	0.010

Cyp4ac1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
cardiovascular system disease	DOID:1287	0.505
vascular disease	DOID:178	0.505
disease of anatomical entity	DOID:7	0.505
hypertension	DOID:10763	0.370
artery disease	DOID:0050828	0.370
essential hypertension	DOID:10825	0.370
nervous system disease	DOID:863	0.020
disease of metabolism	DOID:0014667	0.011
central nervous system disease	DOID:331	0.011
neurodegenerative disease	DOID:1289	0.011

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