Drosophila melanogaster

113 known processes

Rop (Dmel_CG15811)

Ras opposite

(Aliases: l(3)SH16,Dmel\CG15811,SEC1,CG15811,ras2,l(3)64Ah,rop,rop(Sec1),ROP,cs1)

Rop biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
oocyte differentiationGO:00099941450.892
oocyte developmentGO:00485991240.711
oocyte constructionGO:00073081120.584
regionalizationGO:00030024160.485
pole plasm oskar mrna localizationGO:0045451460.470
pole plasm rna localizationGO:0007316520.325
eye developmentGO:00016543230.325
developmental growthGO:00485892800.321
single organism membrane fusionGO:0044801420.316
cytoskeleton dependent cytokinesisGO:0061640810.294
vesicle fusionGO:0006906190.291
cytokinesisGO:0000910900.275
rna localizationGO:00064031150.271
regulation of localizationGO:00328792750.266
cytoplasm organizationGO:0007028640.227
negative regulation of cell communicationGO:00106482230.226
Mouse
establishment of organelle localizationGO:00516561220.225
Mouse Rat Worm
pole plasm assemblyGO:0007315610.221
establishment of localization in cellGO:00516494020.218
regulation of transportGO:00510491810.218
Mouse Rat Worm
organelle localizationGO:00516401480.212
Mouse Rat Worm
germarium derived egg chamber formationGO:00072931010.209
cellular catabolic processGO:00442483720.206
oocyte axis specificationGO:00073091080.204
enzyme linked receptor protein signaling pathwayGO:00071671790.204
embryo development ending in birth or egg hatchingGO:00097921520.201
synaptic vesicle localizationGO:0097479530.194
Mouse Rat Worm
vesicle localizationGO:0051648550.191
Mouse Rat Worm
homeostatic processGO:00425921990.184
establishment or maintenance of microtubule cytoskeleton polarityGO:0030951410.179
anterior posterior axis specificationGO:00099481090.177
synaptic transmissionGO:00072682880.177
single organism intracellular transportGO:19025822070.176
inorganic cation transmembrane transportGO:0098662610.175
developmental maturationGO:00217001720.171
establishment of vesicle localizationGO:0051650510.170
Mouse Rat Worm
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.170
tissue migrationGO:00901301550.169
response to light stimulusGO:00094161240.160
organelle fissionGO:00482853400.153
single organism cellular localizationGO:19025801800.152
organelle fusionGO:0048284460.138
cellular macromolecule localizationGO:00707272200.136
cell proliferationGO:00082832990.136
regulation of tube sizeGO:0035150460.136
single organism membrane organizationGO:0044802930.135
axis specificationGO:00097981670.134
segmentationGO:00352822070.131
positive regulation of cell communicationGO:00106472500.130
Worm
regulation of multi organism processGO:00439001310.130
vesicle mediated transportGO:00161923810.128
Mouse Rat Worm
agingGO:00075681430.123
secretion by cellGO:00329401010.115
cell divisionGO:00513012480.108
intracellular mrna localization involved in pattern specification processGO:0060810560.107
establishment or maintenance of cell polarityGO:00071631670.104
cell maturationGO:00484691440.104
epithelial cell differentiationGO:00308553220.104
negative regulation of response to stimulusGO:00485852580.100
blastoderm segmentationGO:00073501590.099
axon guidanceGO:00074112330.099
axon developmentGO:00615642970.099
Mouse
synaptic vesicle fusion to presynaptic membraneGO:003162970.096
embryonic axis specificationGO:00005781070.091
maternal determination of anterior posterior axis embryoGO:0008358740.091
exocytosisGO:0006887280.090
Mouse Rat Worm
anterior posterior axis specification embryoGO:00085951030.089
secretionGO:00469031090.088
regulation of developmental growthGO:00486381740.088
monovalent inorganic cation transportGO:0015672400.086
mitotic nuclear divisionGO:00070672130.084
muscle structure developmentGO:00610612240.083
cation transmembrane transportGO:0098655880.082
tripartite regional subdivisionGO:00073511030.081
single fertilizationGO:0007338240.080
appendage morphogenesisGO:00351073970.079
pole plasm mrna localizationGO:0019094490.079
compound eye developmentGO:00487493070.078
oocyte microtubule cytoskeleton organizationGO:0016325350.077
nuclear divisionGO:00002803320.075
negative regulation of cellular metabolic processGO:00313243820.075
cell growthGO:00160491080.074
phosphorylationGO:00163102940.072
membrane fusionGO:0061025420.070
imaginal disc derived appendage developmentGO:00487373990.070
organic substance transportGO:00717022570.070
cellular protein modification processGO:00064644380.069
fertilizationGO:0009566260.068
sensory organ morphogenesisGO:00905962600.067
intracellular mrna localizationGO:0008298660.067
molting cycleGO:0042303560.066
post embryonic appendage morphogenesisGO:00351203850.066
eye morphogenesisGO:00485922600.064
positive regulation of signalingGO:00230562430.064
Worm
epidermal growth factor receptor signaling pathwayGO:0007173580.063
regulation of multicellular organismal developmentGO:20000264140.062
multicellular organismal agingGO:00102591400.061
proteolysisGO:00065081920.060
negative regulation of gene expressionGO:00106293870.059
determination of adult lifespanGO:00083401370.059
regulation of secretionGO:0051046440.058
Mouse Rat Worm
morphogenesis of an epitheliumGO:00020092760.058
regulation of anatomical structure sizeGO:00900661630.057
response to abiotic stimulusGO:00096283410.057
establishment of synaptic vesicle localizationGO:0097480500.057
Mouse Rat Worm
tube developmentGO:00352952440.057
cellular response to chemical stimulusGO:00708871990.057
response to organic substanceGO:00100332840.055
central nervous system developmentGO:00074172010.054
defense responseGO:00069523000.054
rna splicingGO:0008380830.053
regulation of cell cycle processGO:00105641810.053
imaginal disc derived appendage morphogenesisGO:00351143950.053
mitotic spindle organizationGO:00070522200.052
growthGO:00400073590.052
open tracheal system developmentGO:00074242040.051
actin cytoskeleton organizationGO:00300362060.050
ovarian follicle cell migrationGO:00072971210.050
positive regulation of secretionGO:0051047220.050
Mouse Rat Worm
intracellular mrna localization involved in anterior posterior axis specificationGO:0060811530.049
response to external biotic stimulusGO:00432072930.049
regulation of actin filament based processGO:0032970420.048
positive regulation of transportGO:0051050920.048
Mouse Rat Worm
detection of abiotic stimulusGO:0009582660.047
embryonic morphogenesisGO:00485982060.046
negative regulation of signal transductionGO:00099682060.046
cell cell junction assemblyGO:0007043380.045
establishment or maintenance of cytoskeleton polarityGO:0030952440.045
germarium derived female germ line cyst formationGO:0030727420.045
protein complex assemblyGO:00064612000.044
Rat
epithelial cell developmentGO:00020642740.044
regulation of protein metabolic processGO:00512462560.044
macromolecule catabolic processGO:00090571610.043
protein catabolic processGO:00301631010.043
ion transmembrane transportGO:00342201220.042
regulation of cellular protein metabolic processGO:00322682430.042
organic substance catabolic processGO:19015753080.042
tissue morphogenesisGO:00487292970.042
protein modification processGO:00362114380.042
golgi vesicle transportGO:0048193270.042
positive regulation of multicellular organismal processGO:00512401430.042
neuromuscular synaptic transmissionGO:0007274670.041
Mouse
regulation of phosphate metabolic processGO:00192202100.041
regulation of synaptic transmissionGO:0050804690.040
Mouse Rat Worm
regulation of catabolic processGO:00098941700.040
regulation of mitotic cell cycleGO:00073461900.040
intracellular transportGO:00469072280.039
germ line cyst formationGO:0048134440.039
regulation of cell cycleGO:00517262910.039
respiratory system developmentGO:00605412130.039
programmed cell deathGO:00125012570.039
Mouse
anterior posterior pattern specificationGO:00099521360.039
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092380.038
purine nucleoside triphosphate metabolic processGO:00091441190.037
appendage developmentGO:00487364010.037
ion transportGO:00068111450.037
cell motilityGO:00488702510.037
chromosome segregationGO:00070591570.036
gliogenesisGO:0042063800.036
ovarian follicle cell developmentGO:00307072480.036
ameboidal type cell migrationGO:00016671510.036
cell migrationGO:00164772380.036
oocyte microtubule cytoskeleton polarizationGO:0008103220.035
molting cycle chitin based cuticleGO:0007591560.035
positive regulation of developmental processGO:00510941430.035
apoptotic processGO:00069151590.035
Mouse
neurotransmitter secretionGO:0007269350.035
modification dependent protein catabolic processGO:0019941780.035
regulation of proteasomal protein catabolic processGO:0061136390.035
regulation of cellular component movementGO:0051270420.034
response to woundingGO:0009611940.034
embryonic pattern specificationGO:00098801740.034
meiotic nuclear divisionGO:00071261510.033
negative regulation of signalingGO:00230572190.033
Mouse
positive regulation of cellular component organizationGO:00511301560.033
detection of light stimulusGO:0009583580.032
neuron projection guidanceGO:00974852410.032
skeletal muscle organ developmentGO:0060538480.031
dorsal ventral pattern formationGO:00099531330.031
regulation of response to external stimulusGO:00321011150.031
cellular macromolecule catabolic processGO:00442651360.031
synaptic vesicle recyclingGO:0036465280.031
Mouse
metal ion transportGO:0030001740.031
protein localizationGO:00081042840.030
positive regulation of response to stimulusGO:00485843230.030
modification dependent macromolecule catabolic processGO:0043632790.030
female germ line cyst formationGO:0048135420.030
cation transportGO:00068121100.029
imaginal disc derived wing morphogenesisGO:00074763370.029
columnar cuboidal epithelial cell developmentGO:00020662490.029
catabolic processGO:00090564090.029
regulation of epithelial cell proliferationGO:005067840.028
regulation of cellular localizationGO:00603411360.028
cellular response to organic substanceGO:00713101320.028
negative regulation of protein metabolic processGO:0051248850.027
cuticle developmentGO:0042335860.027
regulation of reproductive processGO:2000241540.027
glial cell developmentGO:0021782270.027
nucleus localizationGO:0051647340.027
synaptic vesicle transportGO:0048489500.027
Mouse Rat Worm
phototransductionGO:0007602520.027
axonogenesisGO:00074092900.026
Mouse
atp metabolic processGO:0046034490.026
cellular response to heatGO:0034605240.026
cytoplasmic transport nurse cell to oocyteGO:0007303120.026
establishment of blood brain barrierGO:0060856160.026
tube morphogenesisGO:00352391910.026
epithelium migrationGO:00901321480.026
chitin based cuticle developmentGO:0040003490.026
cytoskeleton dependent intracellular transportGO:0030705440.025
membrane organizationGO:00610241120.025
cell cell junction organizationGO:0045216550.025
regulation of dendrite morphogenesisGO:0048814280.025
intracellular protein transportGO:00068861040.025
actin filament based processGO:00300292200.025
positive regulation of secretion by cellGO:1903532200.025
Mouse Rat Worm
erbb signaling pathwayGO:0038127580.025
wing disc morphogenesisGO:00074723440.024
localization of cellGO:00516742570.024
lipid modificationGO:0030258240.024
cell fate determinationGO:0001709910.024
spindle assemblyGO:0051225800.024
ubiquitin dependent protein catabolic processGO:0006511780.024
actin filament based movementGO:0030048260.024
mitotic cytokinesisGO:0000281500.024
protein transportGO:00150311550.024
regulation of cell cycle phase transitionGO:19019871300.023
digestive system developmentGO:00551231490.023
organonitrogen compound metabolic processGO:19015643180.023
dephosphorylationGO:0016311510.023
regulation of cell divisionGO:0051302720.023
regulation of cell differentiationGO:00455953020.023
pronuclear migrationGO:003504640.023
establishment of protein localizationGO:00451841630.022
nitrogen compound transportGO:0071705850.022
intracellular signal transductionGO:00355563000.022
deathGO:00162652840.022
Mouse
response to biotic stimulusGO:00096072940.022
morphogenesis of follicular epitheliumGO:0016333360.021
inorganic ion transmembrane transportGO:0098660730.021
response to starvationGO:0042594970.021
microtubule based transportGO:0010970420.021
protein complex biogenesisGO:00702712010.021
Rat
response to organophosphorusGO:004668320.020
positive regulation of nucleobase containing compound metabolic processGO:00459353320.020
purine nucleoside monophosphate metabolic processGO:0009126500.020
protein phosphorylationGO:00064681690.020
response to other organismGO:00517072930.020
autophagyGO:00069141080.020
chemotaxisGO:00069352490.020
neurotransmitter transportGO:0006836370.020
establishment or maintenance of bipolar cell polarityGO:0061245340.020
establishment of nucleus localizationGO:0040023260.020
cell deathGO:00082192790.019
Mouse
immune system processGO:00023763470.019
proteolysis involved in cellular protein catabolic processGO:0051603830.019
regulation of transmembrane transportGO:0034762270.019
regulation of growthGO:00400082330.019
developmental cell growthGO:0048588520.019
regulation of phosphorus metabolic processGO:00511742100.019
regulation of neuron differentiationGO:00456641030.019
purine containing compound catabolic processGO:00725231120.019
nucleoside triphosphate metabolic processGO:00091411200.019
atp catabolic processGO:0006200380.019
organic cyclic compound catabolic processGO:19013611680.019
signal transduction by phosphorylationGO:00230141070.018
positive regulation of rna metabolic processGO:00512542710.018
endomembrane system organizationGO:00102561190.018
organelle assemblyGO:00709251980.018
phagocytosisGO:00069092150.018
nuclear migrationGO:0007097200.018
protein processingGO:0016485680.018
protein maturationGO:0051604710.018
forebrain developmentGO:003090020.018
regulation of cellular catabolic processGO:00313291570.018
digestive tract morphogenesisGO:00485461270.017
positive regulation of signal transductionGO:00099672230.017
branching involved in open tracheal system developmentGO:0060446450.017
proteasomal protein catabolic processGO:0010498590.017
actin mediated cell contractionGO:0070252210.017
synaptic vesicle primingGO:001608210.017
Rat
signal releaseGO:0023061490.017
transcription from rna polymerase ii promoterGO:00063663680.017
single organism catabolic processGO:00447122280.017
ribonucleoside monophosphate metabolic processGO:0009161510.017
nucleobase containing compound transportGO:0015931560.017
mrna processingGO:00063971040.017
regulation of cell morphogenesisGO:00226041630.017
regulation of molecular functionGO:00650092170.017
autophagic vacuole assemblyGO:000004520.017
ribose phosphate metabolic processGO:00196931450.017
epithelial cell migrationGO:00106311480.016
regulation of synaptic plasticityGO:0048167140.016
Mouse
negative regulation of cell cycleGO:00457861160.016
defense response to other organismGO:00985422250.016
ribonucleoside metabolic processGO:00091191270.016
larval developmentGO:00021641040.016
negative regulation of cellular protein metabolic processGO:0032269850.016
maintenance of locationGO:0051235730.016
cellular protein localizationGO:00346131600.016
organonitrogen compound catabolic processGO:19015651280.016
macromolecular complex assemblyGO:00650032560.016
Rat
cell cycle phase transitionGO:00447701400.016
cellular protein complex assemblyGO:0043623710.016
Rat
spermatogenesisGO:00072832000.016
wnt signaling pathwayGO:0016055980.016
purine nucleoside metabolic processGO:00422781270.016
telencephalon developmentGO:002153720.015
actin filament organizationGO:00070151260.015
negative regulation of phosphorus metabolic processGO:0010563450.015
pigmentationGO:0043473750.015
chemical homeostasisGO:0048878920.015
compound eye morphogenesisGO:00017452490.015
action potentialGO:0001508130.015
cellular protein catabolic processGO:0044257830.015
regulation of programmed cell deathGO:00430671520.015
Mouse
response to oxygen containing compoundGO:19017002000.015
neuromuscular junction developmentGO:00075281490.015
epidermis developmentGO:0008544650.015
neurological system processGO:00508773580.015
neuronal action potentialGO:0019228100.014
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434370.014
endocytosisGO:00068973100.014
Mouse
regulation of neuron projection developmentGO:0010975690.014
regulation of cellular component biogenesisGO:00440872010.014
photoreceptor cell differentiationGO:00465301700.014
regulation of rna splicingGO:0043484690.014
nucleoside monophosphate metabolic processGO:0009123520.014
ribonucleoside triphosphate metabolic processGO:00091991190.014
potassium ion transportGO:0006813200.014
neuron recognitionGO:00080381010.014
regulation of wnt signaling pathwayGO:0030111680.014
kidney developmentGO:000182230.013
oxoacid metabolic processGO:00434361030.013
positive regulation of nucleic acid templated transcriptionGO:19035082660.013
negative regulation of cellular biosynthetic processGO:00313272770.013
monocarboxylic acid transportGO:001571830.013
posttranscriptional regulation of gene expressionGO:00106081450.013
Rat
developmental pigmentationGO:0048066680.013
regulation of phosphorylationGO:00423251470.013
meiotic cell cycle processGO:19030461320.013
purine ribonucleotide catabolic processGO:00091541090.013
mapk cascadeGO:00001651070.013
epithelial cell proliferationGO:0050673150.013
regulation of cellular component sizeGO:0032535980.013
border follicle cell migrationGO:00072981130.013
circulatory system processGO:0003013370.013
protein targetingGO:0006605640.013
positive regulation of cell cycleGO:0045787430.013
nucleoside phosphate catabolic processGO:19012921100.013
cellular response to molecule of bacterial originGO:007121930.013
oocyte dorsal ventral axis specificationGO:0007310340.013
regulation of blood circulationGO:1903522210.013
anatomical structure homeostasisGO:0060249970.013
small molecule metabolic processGO:00442813050.013
single organism biosynthetic processGO:00447112060.013
regulation of mrna metabolic processGO:1903311720.012
positive regulation of nitrogen compound metabolic processGO:00511733540.012
regulation of response to stressGO:00801342000.012
regulation of oocyte developmentGO:0060281270.012
establishment or maintenance of polarity of follicular epitheliumGO:0016334260.012
skeletal muscle fiber developmentGO:004874130.012
regulation of pole plasm oskar mrna localizationGO:0007317270.012
eye photoreceptor cell differentiationGO:00017541450.012
regulation of catalytic activityGO:00507901850.012
negative regulation of organelle organizationGO:0010639560.012
meiotic cell cycleGO:00513211710.012
regulation of nervous system developmentGO:00519602480.012
purine ribonucleoside monophosphate metabolic processGO:0009167500.012
purine nucleoside monophosphate catabolic processGO:0009128380.012
purine nucleotide catabolic processGO:00061951090.012
regulation of cell deathGO:00109411730.012
Mouse
regulation of cell projection organizationGO:0031344920.012
meiotic chromosome segregationGO:0045132590.012
spinal cord developmentGO:002151010.012
lipid metabolic processGO:00066291210.011
ribonucleoside monophosphate catabolic processGO:0009158390.011
ribonucleoside triphosphate catabolic processGO:00092031080.011
regulation of establishment of protein localizationGO:0070201610.011
regulation of neurogenesisGO:00507671580.011
detection of stimulusGO:00516061560.011
cell junction organizationGO:0034330570.011
transmembrane transportGO:00550851390.011
dendrite morphogenesisGO:00488131990.011
regulation of necrotic cell deathGO:001093910.011
oxidation reduction processGO:00551141230.011
apical junction assemblyGO:0043297320.011
regulation of system processGO:0044057360.011
regulation of protein phosphorylationGO:0001932640.011
camera type eye developmentGO:004301040.011
positive regulation of gene expressionGO:00106282900.011
positive regulation of growthGO:0045927750.011
regulation of synapse structure and activityGO:00508031280.011
mrna metabolic processGO:00160711240.011
cellular macromolecular complex assemblyGO:00346221530.011
Rat
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.011
positive regulation of biosynthetic processGO:00098913160.011
positive regulation of cell proliferationGO:0008284470.011
purine nucleoside biosynthetic processGO:004245130.011
striated muscle cell differentiationGO:0051146900.011
regulation of protein transportGO:0051223570.010
negative regulation of mitotic cell cycleGO:00459301090.010
regulation of immune system processGO:00026821760.010
negative regulation of cell cycle processGO:00109481090.010
cell recognitionGO:00080371020.010
regulation of cellular response to growth factor stimulusGO:0090287130.010
endoplasmic reticulum organizationGO:0007029130.010
necrotic cell deathGO:007026510.010
regulation of organelle organizationGO:00330431960.010
regulation of membrane potentialGO:0042391350.010
axon cargo transportGO:0008088290.010

Rop disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.065
musculoskeletal system diseaseDOID:1700.021