IMP: Integrative Multi-species Prediction

Drosophila melanogaster

10 known processes

RpII33 (Dmel_CG7885)

RNA polymerase II 33kD subunit

(Aliases: RNA Pol II,l34Dg,l(2)k05605,152117_at,Pol II RPII33,pol II,RNA pol II,rpII33,Rpll33,RPB3,l(2)34Dg,RNAP,l(2)br17,PolII,D-rpII33,polII,BG:DS00941.10,Dmel\CG7885,Rpb3,CG7885,RNA polII,br17,PolIIo,Pol II)

FLYBASE: FBgn0026373
Entrez: 34796
UniProtKB: O97183

Process Predictions
Disease Predictions

RpII33 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
negative regulation of gene expression	GO:0010629	387	0.515
mrna metabolic process	GO:0016071	124	0.292
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.264
negative regulation of cellular biosynthetic process	GO:0031327	277	0.184
vesicle mediated transport	GO:0016192	381	0.165
negative regulation of biosynthetic process	GO:0009890	277	0.160
negative regulation of rna metabolic process	GO:0051253	251	0.159
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.147
endocytosis	GO:0006897	310	0.146
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.141
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.138
molting cycle	GO:0042303	56	0.129
negative regulation of transcription dna templated	GO:0045892	237	0.120
transcription from rna polymerase ii promoter	GO:0006366	368	0.117	Human Yeast
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.115
cellular catabolic process	GO:0044248	372	0.103
nuclear division	GO:0000280	332	0.103
negative regulation of cellular metabolic process	GO:0031324	382	0.100
posttranscriptional regulation of gene expression	GO:0010608	145	0.094
regulation of cell cycle	GO:0051726	291	0.091
rna processing	GO:0006396	147	0.084
immune system process	GO:0002376	347	0.084
embryo development ending in birth or egg hatching	GO:0009792	152	0.081	Worm
growth	GO:0040007	359	0.081
establishment of localization in cell	GO:0051649	402	0.081
regulation of meiosis	GO:0040020	3	0.068
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.068
catabolic process	GO:0009056	409	0.067
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.066
programmed cell death	GO:0012501	257	0.065
cell death	GO:0008219	279	0.064
regulation of mitotic cell cycle	GO:0007346	190	0.061
mitotic spindle organization	GO:0007052	220	0.059
mrna processing	GO:0006397	104	0.055
rna splicing	GO:0008380	83	0.055
negative regulation of rna biosynthetic process	GO:1902679	240	0.051
positive regulation of biosynthetic process	GO:0009891	316	0.048
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.047
organic substance transport	GO:0071702	257	0.045
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.044
negative regulation of response to stimulus	GO:0048585	258	0.044
regulation of cell cycle process	GO:0010564	181	0.042
body morphogenesis	GO:0010171	2	0.037
rna splicing via transesterification reactions with bulged adenosine as nucleophile	GO:0000377	73	0.037
rna 3 end processing	GO:0031123	45	0.036
mrna catabolic process	GO:0006402	33	0.035
positive regulation of cellular biosynthetic process	GO:0031328	316	0.034
mrna cis splicing via spliceosome	GO:0045292	1	0.033
spindle organization	GO:0007051	253	0.032
heterocycle catabolic process	GO:0046700	166	0.031
phagocytosis	GO:0006909	215	0.031
positive regulation of gene expression	GO:0010628	290	0.031
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.029
chromatin organization	GO:0006325	207	0.028
organic cyclic compound catabolic process	GO:1901361	168	0.028
organic substance catabolic process	GO:1901575	308	0.027
nucleobase containing compound catabolic process	GO:0034655	165	0.026
mitotic dna damage checkpoint	GO:0044773	74	0.025
chromosome organization	GO:0051276	360	0.025
organonitrogen compound metabolic process	GO:1901564	318	0.025
small molecule metabolic process	GO:0044281	305	0.025
nitrogen compound transport	GO:0071705	85	0.025
regulation of organelle organization	GO:0033043	196	0.025
response to biotic stimulus	GO:0009607	294	0.025
developmental growth	GO:0048589	280	0.024
positive regulation of rna biosynthetic process	GO:1902680	266	0.024
spliceosomal snrnp assembly	GO:0000387	2	0.023
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.023
death	GO:0016265	284	0.023
regulation of hydrolase activity	GO:0051336	97	0.022
localization of cell	GO:0051674	257	0.022
regulation of growth	GO:0040008	233	0.022
apoptotic process	GO:0006915	159	0.022
negative regulation of mitotic cell cycle	GO:0045930	109	0.022
protein neddylation	GO:0045116	5	0.021
cellular macromolecule localization	GO:0070727	220	0.021
centrosome organization	GO:0051297	163	0.021
anatomical structure homeostasis	GO:0060249	97	0.021
mrna splicing via spliceosome	GO:0000398	73	0.020
positive regulation of macromolecule metabolic process	GO:0010604	405	0.020
meiotic cell cycle	GO:0051321	171	0.020
cytoplasmic transport	GO:0016482	130	0.020
cell motility	GO:0048870	251	0.020
aromatic compound catabolic process	GO:0019439	166	0.019
hydrogen peroxide catabolic process	GO:0042744	6	0.019
defense response	GO:0006952	300	0.019
regulation of programmed cell death	GO:0043067	152	0.019
prostanoid biosynthetic process	GO:0046457	1	0.019
regulation of multi organism process	GO:0043900	131	0.018
positive regulation of transcription dna templated	GO:0045893	266	0.018
regulation of response to stress	GO:0080134	200	0.018
ncrna 3 end processing	GO:0043628	17	0.017
intracellular transport	GO:0046907	228	0.017
response to abiotic stimulus	GO:0009628	341	0.017
establishment of protein localization	GO:0045184	163	0.017
macromolecule catabolic process	GO:0009057	161	0.017
secretion by cell	GO:0032940	101	0.017
cellular response to chemical stimulus	GO:0070887	199	0.016
regulation of atpase activity	GO:0043462	4	0.016
regulation of protein metabolic process	GO:0051246	256	0.016
regulation of immune system process	GO:0002682	176	0.016
cell division	GO:0051301	248	0.016
cellular protein localization	GO:0034613	160	0.016
telomere maintenance	GO:0000723	21	0.016
regulation of cell death	GO:0010941	173	0.016
aging	GO:0007568	143	0.016
purine containing compound metabolic process	GO:0072521	155	0.016
mitotic dna integrity checkpoint	GO:0044774	75	0.016
mitochondrial membrane organization	GO:0007006	3	0.015
meiotic nuclear division	GO:0007126	151	0.015
rna splicing via transesterification reactions	GO:0000375	73	0.015
cellular nitrogen compound catabolic process	GO:0044270	165	0.015
regulation of cdc42 protein signal transduction	GO:0032489	3	0.015
response to other organism	GO:0051707	293	0.015
regulation of cellular protein metabolic process	GO:0032268	243	0.015
regulation of striated muscle contraction	GO:0006942	2	0.014
negative regulation of intrinsic apoptotic signaling pathway	GO:2001243	1	0.014
mitotic cell cycle checkpoint	GO:0007093	88	0.014
protein processing	GO:0016485	68	0.014
response to organic substance	GO:0010033	284	0.014
establishment of rna localization	GO:0051236	47	0.013
regulation of localization	GO:0032879	275	0.013
regulation of catalytic activity	GO:0050790	185	0.013
regulation of molecular function	GO:0065009	217	0.013
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.013
protein modification process	GO:0036211	438	0.013
ribonucleotide metabolic process	GO:0009259	145	0.013
positive regulation of multicellular organismal process	GO:0051240	143	0.013
eye development	GO:0001654	323	0.013
regulation of nuclear division	GO:0051783	58	0.013
larval development	GO:0002164	104	0.013	Worm
positive regulation of binding	GO:0051099	4	0.013
rna localization	GO:0006403	115	0.012
single organism catabolic process	GO:0044712	228	0.012
protein localization	GO:0008104	284	0.012
nucleoside phosphate metabolic process	GO:0006753	162	0.012
organophosphate catabolic process	GO:0046434	112	0.012
covalent chromatin modification	GO:0016569	106	0.012
mitotic cell cycle phase transition	GO:0044772	138	0.012
chromosome segregation	GO:0007059	157	0.012
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.012
posttranscriptional gene silencing	GO:0016441	46	0.012
cell chemotaxis involved in malpighian tubule morphogenesis	GO:0061352	3	0.011
positive regulation of cellular protein metabolic process	GO:0032270	118	0.011
response to external biotic stimulus	GO:0043207	293	0.011
cellular response to nutrient	GO:0031670	1	0.011
protein transport	GO:0015031	155	0.011
cell cycle checkpoint	GO:0000075	95	0.011
nuclear transcribed mrna catabolic process	GO:0000956	24	0.011
chromatin modification	GO:0016568	147	0.011
gene silencing	GO:0016458	138	0.011
hatching	GO:0035188	4	0.010	Worm
regulation of cellular localization	GO:0060341	136	0.010
positive regulation of cell communication	GO:0010647	250	0.010
macromolecular complex assembly	GO:0065003	256	0.010
negative regulation of programmed cell death	GO:0043069	72	0.010
homeostatic process	GO:0042592	199	0.010
rna transport	GO:0050658	46	0.010

RpII33 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.020

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