Drosophila melanogaster

0 known processes

crp (Dmel_CG7664)

cropped

(Aliases: l(2)SH2 1614,l(2)35Fd,l(2)SH1614,l(2)k00809,Dmel\CG7664,l(2)k03505,dAP-4,MS:35F.AT17,AP-4,CG7664,AP4,bHLHe63,35F(AT)[[17]],l(2)00232,BG:DS02740.3)

crp biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of gene expression epigeneticGO:00400291280.412
appendage morphogenesisGO:00351073970.303
imaginal disc derived appendage morphogenesisGO:00351143950.262
negative regulation of rna metabolic processGO:00512532510.257
Human
negative regulation of cellular metabolic processGO:00313243820.251
Human
muscle structure developmentGO:00610612240.231
negative regulation of mitotic cell cycle phase transitionGO:19019911030.222
post embryonic appendage morphogenesisGO:00351203850.192
chromatin silencingGO:0006342760.168
intracellular signal transductionGO:00355563000.160
Human
imaginal disc derived appendage developmentGO:00487373990.147
regulation of organ morphogenesisGO:2000027780.141
posttranscriptional gene silencingGO:0016441460.136
macromolecular complex assemblyGO:00650032560.133
Human
protein modification processGO:00362114380.132
Human
wing disc morphogenesisGO:00074723440.129
maintenance of gastrointestinal epitheliumGO:003027730.129
negative regulation of transcription dna templatedGO:00458922370.126
Human
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.117
Human
small molecule metabolic processGO:00442813050.113
apoptotic processGO:00069151590.109
Human
negative regulation of gene expressionGO:00106293870.108
Human
negative regulation of cell cycle phase transitionGO:19019881030.105
cell divisionGO:00513012480.099
oxoacid metabolic processGO:00434361030.088
tissue morphogenesisGO:00487292970.087
heart developmentGO:0007507820.083
negative regulation of rna biosynthetic processGO:19026792400.080
Human
gene silencingGO:00164581380.079
regulation of intracellular signal transductionGO:19025312360.078
dorsal ventral pattern formationGO:00099531330.078
regulation of organelle organizationGO:00330431960.077
ras protein signal transductionGO:0007265880.076
photoreceptor cell differentiationGO:00465301700.076
protein complex assemblyGO:00064612000.074
Human
negative regulation of nitrogen compound metabolic processGO:00511722650.074
Human
cellular response to external stimulusGO:0071496660.071
phosphorylationGO:00163102940.070
Human
cellular macromolecular complex assemblyGO:00346221530.069
positive regulation of cell communicationGO:00106472500.068
regulation of mitotic cell cycleGO:00073461900.067
positive regulation of phosphorus metabolic processGO:00105621390.067
transcription from rna polymerase ii promoterGO:00063663680.066
Human
positive regulation of signal transductionGO:00099672230.063
negative regulation of cellular protein metabolic processGO:0032269850.062
Human
appendage developmentGO:00487364010.062
synapse assemblyGO:00074161430.061
regulation of cell divisionGO:0051302720.061
positive regulation of nucleobase containing compound metabolic processGO:00459353320.061
Human
gene silencing by rnaGO:0031047570.061
compound eye developmentGO:00487493070.059
mitotic cell cycle checkpointGO:0007093880.058
defense response to virusGO:0051607230.058
rna processingGO:00063961470.058
positive regulation of intracellular signal transductionGO:19025331160.057
positive regulation of signalingGO:00230562430.056
negative regulation of biosynthetic processGO:00098902770.056
Human
cellular protein modification processGO:00064644380.053
Human
positive regulation of nitrogen compound metabolic processGO:00511733540.053
Human
regulation of cell cycle phase transitionGO:19019871300.053
regulation of epithelial cell differentiationGO:003085640.052
response to mechanical stimulusGO:0009612280.052
spermatogenesisGO:00072832000.052
muscle organ developmentGO:00075171270.052
protein complex biogenesisGO:00702712010.051
Human
gland developmentGO:00487321910.050
small gtpase mediated signal transductionGO:0007264880.049
rna interferenceGO:0016246270.049
wnt signaling pathwayGO:0016055980.049
mrna catabolic processGO:0006402330.049
regulation of protein metabolic processGO:00512462560.049
Human
nephron morphogenesisGO:007202830.049
response to abiotic stimulusGO:00096283410.049
chromosome organizationGO:00512763600.048
hindbrain developmentGO:003090220.048
regulation of molecular functionGO:00650092170.047
Human
compound eye morphogenesisGO:00017452490.047
regulation of response to stressGO:00801342000.047
regulation of phosphate metabolic processGO:00192202100.047
Human
posttranscriptional gene silencing by rnaGO:0035194450.046
regulation of small gtpase mediated signal transductionGO:0051056930.046
circulatory system developmentGO:0072359820.045
cellular response to mechanical stimulusGO:007126020.045
sensory organ morphogenesisGO:00905962600.045
homeostatic processGO:00425921990.045
nephron developmentGO:007200630.044
cellular macromolecule catabolic processGO:00442651360.044
nephron epithelium morphogenesisGO:007208830.044
regulation of mitosisGO:0007088560.044
negative regulation of macromolecule biosynthetic processGO:00105582700.043
Human
autophagyGO:00069141080.043
mrna metabolic processGO:00160711240.043
regulation of heart morphogenesisGO:200082630.043
regulation of epithelial cell proliferationGO:005067840.043
pigmentationGO:0043473750.043
imaginal disc derived wing morphogenesisGO:00074763370.043
cellular response to dna damage stimulusGO:00069742230.043
Human
deathGO:00162652840.042
Human
organic acid metabolic processGO:00060821030.042
regulation of mrna metabolic processGO:1903311720.042
regulation of mrna splicing via spliceosomeGO:0048024640.042
body morphogenesisGO:001017120.041
anatomical structure homeostasisGO:0060249970.041
stem cell maintenanceGO:0019827670.041
programmed cell deathGO:00125012570.041
Human
regulation of defense response to virusGO:0050688140.040
wing disc pattern formationGO:0035222660.040
imaginal disc derived wing vein morphogenesisGO:0008586440.040
cellular catabolic processGO:00442483720.040
cellular component assembly involved in morphogenesisGO:00109271510.040
negative regulation of nucleic acid templated transcriptionGO:19035072400.039
Human
regulation of chromatin silencingGO:0031935360.039
positive regulation of cellular biosynthetic processGO:00313283160.038
Human
maintenance of locationGO:0051235730.038
g2 dna damage checkpointGO:0031572690.038
rna splicing via transesterification reactionsGO:0000375730.037
eye developmentGO:00016543230.036
negative regulation of cell cycleGO:00457861160.036
Human
vesicle mediated transportGO:00161923810.036
regulation of multicellular organismal developmentGO:20000264140.036
negative regulation of mitotic cell cycleGO:00459301090.036
regulation of cellular catabolic processGO:00313291570.036
negative regulation of cell cycle processGO:00109481090.035
Human
posttranscriptional regulation of gene expressionGO:00106081450.035
regulation of programmed cell deathGO:00430671520.035
Human
adult locomotory behaviorGO:0008344760.035
negative regulation of organelle organizationGO:0010639560.035
organelle fissionGO:00482853400.034
regulation of protein modification processGO:00313991120.034
Human
regulation of developmental growthGO:00486381740.034
regulation of cellular protein metabolic processGO:00322682430.034
Human
cellular response to chemical stimulusGO:00708871990.034
positive regulation of biosynthetic processGO:00098913160.033
Human
immune response regulating signaling pathwayGO:000276420.033
regulation of nuclear divisionGO:0051783580.033
neuronal stem cell maintenanceGO:009715040.033
leg disc developmentGO:0035218920.032
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.032
r7 cell differentiationGO:0045466430.032
positive regulation of response to stimulusGO:00485843230.032
cellular macromolecule localizationGO:00707272200.032
regulation of mrna processingGO:0050684710.031
regulation of catalytic activityGO:00507901850.031
Human
organelle assemblyGO:00709251980.031
salivary gland morphogenesisGO:00074351450.031
regulation of response to biotic stimulusGO:0002831630.030
eye morphogenesisGO:00485922600.030
synapse organizationGO:00508081960.030
intracellular protein transportGO:00068861040.030
kidney developmentGO:000182230.030
mitotic cell cycle phase transitionGO:00447721380.030
single organism catabolic processGO:00447122280.030
alternative mrna splicing via spliceosomeGO:0000380600.030
cellular ketone metabolic processGO:0042180240.030
cellular protein complex assemblyGO:0043623710.030
exocrine system developmentGO:00352721620.029
hematopoietic progenitor cell differentiationGO:000224410.029
regulation of meiosisGO:004002030.029
organic substance catabolic processGO:19015753080.028
response to organic substanceGO:00100332840.028
mapk cascadeGO:00001651070.028
regulation of chromosome organizationGO:0033044640.028
spermatid differentiationGO:00485151140.028
nucleobase containing compound catabolic processGO:00346551650.028
negative regulation of chromosome segregationGO:0051985140.028
response to other organismGO:00517072930.028
morphogenesis of an epitheliumGO:00020092760.028
cellular amino acid metabolic processGO:0006520610.027
protein targeting to nucleusGO:0044744510.027
neuroblast proliferationGO:0007405740.027
defense response to other organismGO:00985422250.026
spinal cord developmentGO:002151010.026
chromosome segregationGO:00070591570.026
single organism intracellular transportGO:19025822070.026
determination of adult lifespanGO:00083401370.026
protein transportGO:00150311550.026
cell proliferation involved in imaginal disc derived wing morphogenesisGO:009025520.026
negative regulation of epithelial cell proliferationGO:005068040.026
muscle cell differentiationGO:00426921030.026
taxisGO:00423303040.026
positive regulation of rna metabolic processGO:00512542710.026
Human
regulation of cell cycle processGO:00105641810.026
Human
i kappab phosphorylationGO:000725230.025
positive regulation of organelle organizationGO:0010638650.025
male gamete generationGO:00482322010.025
endocytosisGO:00068973100.025
response to biotic stimulusGO:00096072940.025
multicellular organism growthGO:0035264460.025
regulation of cellular amino acid metabolic processGO:000652100.025
neurological system processGO:00508773580.025
kidney morphogenesisGO:006099330.025
positive regulation of immune system processGO:0002684680.025
response to external biotic stimulusGO:00432072930.024
regulation of immune system processGO:00026821760.024
eye photoreceptor cell differentiationGO:00017541450.024
regulation of cellular component biogenesisGO:00440872010.024
protein localization to nucleusGO:0034504550.024
protein localizationGO:00081042840.024
phagocytosisGO:00069092150.024
carboxylic acid metabolic processGO:0019752920.024
positive regulation of proteolysisGO:0045862520.024
kidney epithelium developmentGO:007207330.023
single organism nuclear importGO:1902593510.023
locomotory behaviorGO:00076261760.023
dna integrity checkpointGO:0031570810.023
positive regulation of macromolecule metabolic processGO:00106044050.023
Human
positive regulation of humoral immune responseGO:0002922280.023
sister chromatid segregationGO:0000819920.023
molting cycle chitin based cuticleGO:0007591560.023
negative regulation of sequence specific dna binding transcription factor activityGO:004343340.023
establishment of planar polarityGO:0001736870.023
single organism cellular localizationGO:19025801800.023
compound eye photoreceptor cell differentiationGO:00017511400.023
regulation of autophagyGO:0010506620.023
cell cycle checkpointGO:0000075950.023
positive regulation of protein metabolic processGO:00512471280.023
positive regulation of cellular component organizationGO:00511301560.023
regulation of stress activated mapk cascadeGO:0032872410.022
cell deathGO:00082192790.022
Human
agingGO:00075681430.022
cellular response to organic substanceGO:00713101320.022
nephron tubule morphogenesisGO:007207830.022
negative regulation of developmental processGO:00510932010.022
regulation of apoptotic processGO:00429811300.022
Human
neuron projection guidanceGO:00974852410.022
protein phosphorylationGO:00064681690.021
Human
regulation of i kappab kinase nf kappab signalingGO:004312220.021
establishment or maintenance of cell polarityGO:00071631670.021
positive regulation of nf kappab import into nucleusGO:004234610.021
regulation of wnt signaling pathwayGO:0030111680.021
regulation of ras protein signal transductionGO:0046578930.021
positive regulation of phosphate metabolic processGO:00459371390.021
regulation of alternative mrna splicing via spliceosomeGO:0000381600.021
immune response activating signal transductionGO:000275720.020
mitotic dna integrity checkpointGO:0044774750.020
regulation of organ formationGO:000315630.020
positive regulation of programmed cell deathGO:0043068620.020
Human
stem cell differentiationGO:00488631170.020
heterocycle catabolic processGO:00467001660.020
negative regulation of gene expression epigeneticGO:0045814770.020
adult behaviorGO:00305341370.020
nuclear transportGO:0051169720.020
embryonic morphogenesisGO:00485982060.020
regulation of mitotic cell cycle phase transitionGO:19019901300.020
imaginal disc pattern formationGO:0007447910.020
regulation of multicellular organism growthGO:0040014400.020
defense response to bacteriumGO:00427421780.019
negative regulation of sister chromatid segregationGO:0033046130.019
mrna processingGO:00063971040.019
intracellular transportGO:00469072280.019
regulation of cellular amine metabolic processGO:003323830.019
protein import into nucleusGO:0006606510.019
positive regulation of macroautophagyGO:001623980.019
axon developmentGO:00615642970.019
negative regulation of cellular component organizationGO:00511291080.019
mitotic cell cycle embryonicGO:0045448380.019
positive regulation of phosphorylationGO:0042327870.019
germ line stem cell maintenanceGO:0030718500.019
mitotic nuclear divisionGO:00070672130.019
negative regulation of stem cell differentiationGO:200073780.018
regulation of cellular response to stressGO:0080135890.018
heart morphogenesisGO:0003007320.018
stem cell fate commitmentGO:0048865250.018
nephron epithelium developmentGO:007200930.018
nuclear divisionGO:00002803320.018
cytoplasmic transportGO:00164821300.018
regulation of transcription from rna polymerase ii promoterGO:00063573780.018
Human
regulation of establishment of planar polarityGO:0090175220.018
asymmetric cell divisionGO:0008356370.018
cell fate specificationGO:0001708710.018
mitotic spindle organizationGO:00070522200.018
spindle organizationGO:00070512530.018
regulation of cell cycleGO:00517262910.018
Human
cellular protein localizationGO:00346131600.018
regulation of protein complex assemblyGO:0043254420.018
monocarboxylic acid transportGO:001571830.018
nephron tubule developmentGO:007208030.018
embryo development ending in birth or egg hatchingGO:00097921520.017
organic cyclic compound catabolic processGO:19013611680.017
positive regulation of cellular protein metabolic processGO:00322701180.017
regulation of phosphorus metabolic processGO:00511742100.017
Human
endomembrane system organizationGO:00102561190.017
cell migrationGO:00164772380.017
endoderm formationGO:000170630.017
positive regulation of molecular functionGO:00440931360.017
positive regulation of developmental processGO:00510941430.017
organelle localizationGO:00516401480.017
positive regulation of cellular component biogenesisGO:0044089800.017
positive regulation of autophagyGO:0010508210.017
catabolic processGO:00090564090.017
peptidyl amino acid modificationGO:00181931050.017
activation of innate immune responseGO:000221840.017
generation of precursor metabolites and energyGO:0006091420.017
epithelial cell differentiationGO:00308553220.016
mitotic sister chromatid segregationGO:0000070870.016
synaptic transmissionGO:00072682880.016
positive regulation of ras protein signal transductionGO:0046579430.016
regulation of cell deathGO:00109411730.016
Human
mitotic sister chromatid separationGO:0051306300.016
positive regulation of transcription dna templatedGO:00458932660.016
Human
hormone biosynthetic processGO:0042446200.016
regulation of jnk cascadeGO:0046328400.016
cell growthGO:00160491080.016
response to ecdysoneGO:0035075340.016
cellular response to transforming growth factor beta stimulusGO:0071560180.016
innate immune responseGO:00450871440.016
cell cell signaling involved in cell fate commitmentGO:00451682100.016
positive regulation of multicellular organismal processGO:00512401430.016
forebrain developmentGO:003090020.016
regulation of neuroblast proliferationGO:1902692340.016
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.016
somatic stem cell maintenanceGO:0035019140.016
organic substance transportGO:00717022570.016
biological adhesionGO:00226101380.016
response to organic cyclic compoundGO:0014070890.016
muscle cell developmentGO:0055001500.015
response to monosaccharideGO:003428440.015
regulation of immune responseGO:00507761180.015
response to lipopolysaccharideGO:003249640.015
regulation of catabolic processGO:00098941700.015
immune responseGO:00069552460.015
response to transforming growth factor betaGO:0071559180.015
regulation of defense response to bacteriumGO:1900424300.015
immune effector processGO:0002252980.015
regulation of microtubule based processGO:0032886490.015
mitotic dna damage checkpointGO:0044773740.015
regulation of stem cell differentiationGO:2000736140.015
bmp signaling pathway involved in malpighian tubule cell chemotaxisGO:006135330.015
response to oxygen containing compoundGO:19017002000.015
regulation of transportGO:00510491810.015
rna catabolic processGO:0006401370.015
response to endogenous stimulusGO:00097191190.015
positive regulation of stem cell differentiationGO:200073830.015
mesenchymal cell developmentGO:001403110.015
negative regulation of chromosome organizationGO:2001251190.015
stem cell developmentGO:0048864790.014
regulation of cellular ketone metabolic processGO:001056530.014
regulation of compound eye retinal cell programmed cell deathGO:0046669180.014
humoral immune responseGO:00069591170.014
negative regulation of cell differentiationGO:00455961430.014
mesenchymal cell differentiationGO:004876210.014
developmental growthGO:00485892800.014
notch signaling pathwayGO:00072191200.014
rna 3 end processingGO:0031123450.014
positive regulation of cellular amino acid metabolic processGO:004576400.014
tissue homeostasisGO:0001894360.014
regulation of mapk cascadeGO:0043408920.014
lamellipodium organizationGO:0097581210.014
amine metabolic processGO:0009308120.014
carbohydrate derivative metabolic processGO:19011352170.014
detection of stimulus involved in sensory perceptionGO:0050906920.014
instar larval developmentGO:0002168550.014
regulation of intracellular transportGO:0032386640.014
organonitrogen compound metabolic processGO:19015643180.014
imaginal disc derived leg morphogenesisGO:0007480800.014
regulation of proteolysisGO:0030162870.013
regulation of protein modification by small protein conjugation or removalGO:1903320250.013
cell cycle arrestGO:000705040.013
Human
regulation of developmental pigmentationGO:0048070240.013
regulation of lipid transportGO:003236830.013
positive regulation of mitotic cell cycleGO:0045931340.013
developmental programmed cell deathGO:00106231380.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092380.013
negative regulation of cell communicationGO:00106482230.013
dorsal ventral axis specificationGO:0009950660.013
multicellular organismal agingGO:00102591400.013
negative regulation of nucleobase containing compound metabolic processGO:00459342610.013
Human
establishment of protein localizationGO:00451841630.013
positive regulation of cell motilityGO:200014730.013
germarium derived egg chamber formationGO:00072931010.013
regulation of timing of cell differentiationGO:004850510.013
tricarboxylic acid metabolic processGO:007235010.013
axon guidanceGO:00074112330.013
negative regulation of nervous system developmentGO:0051961920.013
imaginal disc derived wing margin morphogenesisGO:0008587410.013
positive regulation of response to external stimulusGO:0032103440.013
positive regulation of cell cycle processGO:0090068280.013
extrinsic apoptotic signaling pathwayGO:009719110.013
gland morphogenesisGO:00226121450.013
cellular response to growth factor stimulusGO:0071363300.013
histone methylationGO:0016571400.013
jnk cascadeGO:0007254500.013
regulation of synapse structure and activityGO:00508031280.013
cell motilityGO:00488702510.013
establishment of imaginal disc derived wing hair orientationGO:0001737240.013
regulation of protein polymerizationGO:0032271280.013
regulation of apoptotic signaling pathwayGO:2001233100.012
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377730.012
regulation of synapse assemblyGO:0051963940.012
multicellular organismal signalingGO:0035637120.012
regulation of defense responseGO:00313471020.012
negative regulation of molecular functionGO:0044092510.012
Human
methylationGO:0032259470.012
stem cell proliferationGO:0072089880.012
protein importGO:0017038550.012
skeletal muscle organ developmentGO:0060538480.012
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.012
negative regulation of protein metabolic processGO:0051248850.012
Human
compound eye retinal cell programmed cell deathGO:0046667230.012
muscle system processGO:0003012210.012
signal transduction by phosphorylationGO:00230141070.012
regulation of rna splicingGO:0043484690.012
endodermal cell fate commitmentGO:000171130.012
mitotic g2 dna damage checkpointGO:0007095690.012
apoptotic signaling pathwayGO:0097190270.012
nuclear importGO:0051170510.012
startle responseGO:0001964160.012
neuromuscular processGO:0050905210.012
dna metabolic processGO:00062592270.012
regulation of actin cytoskeleton organizationGO:0032956420.012
chemotaxisGO:00069352490.012
positive regulation of jun kinase activityGO:004350740.012
aggressive behaviorGO:0002118630.012
positive regulation of cytoskeleton organizationGO:0051495210.011
planar cell polarity pathway involved in axis elongationGO:000340230.011
microtubule bundle formationGO:0001578270.011
cellular amide metabolic processGO:0043603800.011
positive regulation of apoptotic processGO:0043065470.011
Human
nf kappab import into nucleusGO:004234810.011
innate immune response in mucosaGO:000222720.011
regulation of immune effector processGO:0002697520.011
larval locomotory behaviorGO:0008345270.011
epithelial structure maintenanceGO:0010669170.011
membrane organizationGO:00610241120.011
cell cycle phase transitionGO:00447701400.011
positive regulation of stress activated mapk cascadeGO:0032874170.011
positive regulation of erk1 and erk2 cascadeGO:0070374360.011
purine ribonucleotide metabolic processGO:00091501450.011
female meiosis chromosome segregationGO:0016321330.011
anterior posterior pattern specificationGO:00099521360.011
regulation of protein catabolic processGO:0042176550.011
positive regulation of rna biosynthetic processGO:19026802660.011
Human
negative regulation of photoreceptor cell differentiationGO:004653380.011
protein localization to organelleGO:0033365820.011
head developmentGO:00603221350.011
jak stat cascadeGO:0007259490.011
regulation of hormone levelsGO:0010817400.011
cellular nitrogen compound catabolic processGO:00442701650.010
spermatid developmentGO:0007286980.010
stress activated protein kinase signaling cascadeGO:0031098550.010
cell fate determinationGO:0001709910.010
positive regulation of production of molecular mediator of immune responseGO:0002702280.010
negative regulation of signalingGO:00230572190.010
macromolecule methylationGO:0043414450.010
camera type eye developmentGO:004301040.010
regulation of antibacterial peptide biosynthetic processGO:0002808220.010
nuclear envelope organizationGO:000699870.010
dna templated transcriptional preinitiation complex assemblyGO:0070897200.010
regulation of phosphatase activityGO:001092130.010
limb morphogenesisGO:003510810.010
compound eye photoreceptor developmentGO:0042051780.010
response to extracellular stimulusGO:00099911160.010

crp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.027
disease of cellular proliferationDOID:1456600.020
neurodegenerative diseaseDOID:128900.016
nervous system diseaseDOID:86300.016
motor neuron diseaseDOID:23100.016
central nervous system diseaseDOID:33100.016
disease of metabolismDOID:001466700.015
musculoskeletal system diseaseDOID:1700.013
cancerDOID:16200.013
organ system cancerDOID:005068600.013