IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

crp (Dmel_CG7664)

cropped

(Aliases: l(2)SH2 1614,l(2)35Fd,l(2)SH1614,l(2)k00809,Dmel\CG7664,l(2)k03505,dAP-4,MS:35F.AT17,AP-4,CG7664,AP4,bHLHe63,35F(AT)[[17]],l(2)00232,BG:DS02740.3)

FLYBASE: FBgn0001994
Entrez: 34956
UniProtKB: Q9V406

Process Predictions
Disease Predictions

crp biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
regulation of gene expression epigenetic	GO:0040029	128	0.412
appendage morphogenesis	GO:0035107	397	0.303
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.262
negative regulation of rna metabolic process	GO:0051253	251	0.257	Human
negative regulation of cellular metabolic process	GO:0031324	382	0.251	Human
muscle structure development	GO:0061061	224	0.231
negative regulation of mitotic cell cycle phase transition	GO:1901991	103	0.222
post embryonic appendage morphogenesis	GO:0035120	385	0.192
chromatin silencing	GO:0006342	76	0.168
intracellular signal transduction	GO:0035556	300	0.160	Human
imaginal disc derived appendage development	GO:0048737	399	0.147
regulation of organ morphogenesis	GO:2000027	78	0.141
posttranscriptional gene silencing	GO:0016441	46	0.136
macromolecular complex assembly	GO:0065003	256	0.133	Human
protein modification process	GO:0036211	438	0.132	Human
wing disc morphogenesis	GO:0007472	344	0.129
maintenance of gastrointestinal epithelium	GO:0030277	3	0.129
negative regulation of transcription dna templated	GO:0045892	237	0.126	Human
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.117	Human
small molecule metabolic process	GO:0044281	305	0.113
apoptotic process	GO:0006915	159	0.109	Human
negative regulation of gene expression	GO:0010629	387	0.108	Human
negative regulation of cell cycle phase transition	GO:1901988	103	0.105
cell division	GO:0051301	248	0.099
oxoacid metabolic process	GO:0043436	103	0.088
tissue morphogenesis	GO:0048729	297	0.087
heart development	GO:0007507	82	0.083
negative regulation of rna biosynthetic process	GO:1902679	240	0.080	Human
gene silencing	GO:0016458	138	0.079
regulation of intracellular signal transduction	GO:1902531	236	0.078
dorsal ventral pattern formation	GO:0009953	133	0.078
regulation of organelle organization	GO:0033043	196	0.077
ras protein signal transduction	GO:0007265	88	0.076
photoreceptor cell differentiation	GO:0046530	170	0.076
protein complex assembly	GO:0006461	200	0.074	Human
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.074	Human
cellular response to external stimulus	GO:0071496	66	0.071
phosphorylation	GO:0016310	294	0.070	Human
cellular macromolecular complex assembly	GO:0034622	153	0.069
positive regulation of cell communication	GO:0010647	250	0.068
regulation of mitotic cell cycle	GO:0007346	190	0.067
positive regulation of phosphorus metabolic process	GO:0010562	139	0.067
transcription from rna polymerase ii promoter	GO:0006366	368	0.066	Human
positive regulation of signal transduction	GO:0009967	223	0.063
negative regulation of cellular protein metabolic process	GO:0032269	85	0.062	Human
appendage development	GO:0048736	401	0.062
synapse assembly	GO:0007416	143	0.061
regulation of cell division	GO:0051302	72	0.061
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.061	Human
gene silencing by rna	GO:0031047	57	0.061
compound eye development	GO:0048749	307	0.059
mitotic cell cycle checkpoint	GO:0007093	88	0.058
defense response to virus	GO:0051607	23	0.058
rna processing	GO:0006396	147	0.058
positive regulation of intracellular signal transduction	GO:1902533	116	0.057
positive regulation of signaling	GO:0023056	243	0.056
negative regulation of biosynthetic process	GO:0009890	277	0.056	Human
cellular protein modification process	GO:0006464	438	0.053	Human
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.053	Human
regulation of cell cycle phase transition	GO:1901987	130	0.053
regulation of epithelial cell differentiation	GO:0030856	4	0.052
response to mechanical stimulus	GO:0009612	28	0.052
spermatogenesis	GO:0007283	200	0.052
muscle organ development	GO:0007517	127	0.052
protein complex biogenesis	GO:0070271	201	0.051	Human
gland development	GO:0048732	191	0.050
small gtpase mediated signal transduction	GO:0007264	88	0.049
rna interference	GO:0016246	27	0.049
wnt signaling pathway	GO:0016055	98	0.049
mrna catabolic process	GO:0006402	33	0.049
regulation of protein metabolic process	GO:0051246	256	0.049	Human
nephron morphogenesis	GO:0072028	3	0.049
response to abiotic stimulus	GO:0009628	341	0.049
chromosome organization	GO:0051276	360	0.048
hindbrain development	GO:0030902	2	0.048
regulation of molecular function	GO:0065009	217	0.047	Human
compound eye morphogenesis	GO:0001745	249	0.047
regulation of response to stress	GO:0080134	200	0.047
regulation of phosphate metabolic process	GO:0019220	210	0.047	Human
posttranscriptional gene silencing by rna	GO:0035194	45	0.046
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.046
circulatory system development	GO:0072359	82	0.045
cellular response to mechanical stimulus	GO:0071260	2	0.045
sensory organ morphogenesis	GO:0090596	260	0.045
homeostatic process	GO:0042592	199	0.045
nephron development	GO:0072006	3	0.044
cellular macromolecule catabolic process	GO:0044265	136	0.044
nephron epithelium morphogenesis	GO:0072088	3	0.044
regulation of mitosis	GO:0007088	56	0.044
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.043	Human
autophagy	GO:0006914	108	0.043
mrna metabolic process	GO:0016071	124	0.043
regulation of heart morphogenesis	GO:2000826	3	0.043
regulation of epithelial cell proliferation	GO:0050678	4	0.043
pigmentation	GO:0043473	75	0.043
imaginal disc derived wing morphogenesis	GO:0007476	337	0.043
cellular response to dna damage stimulus	GO:0006974	223	0.043	Human
death	GO:0016265	284	0.042	Human
organic acid metabolic process	GO:0006082	103	0.042
regulation of mrna metabolic process	GO:1903311	72	0.042
regulation of mrna splicing via spliceosome	GO:0048024	64	0.042
body morphogenesis	GO:0010171	2	0.041
anatomical structure homeostasis	GO:0060249	97	0.041
stem cell maintenance	GO:0019827	67	0.041
programmed cell death	GO:0012501	257	0.041	Human
regulation of defense response to virus	GO:0050688	14	0.040
wing disc pattern formation	GO:0035222	66	0.040
imaginal disc derived wing vein morphogenesis	GO:0008586	44	0.040
cellular catabolic process	GO:0044248	372	0.040
cellular component assembly involved in morphogenesis	GO:0010927	151	0.040
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.039	Human
regulation of chromatin silencing	GO:0031935	36	0.039
positive regulation of cellular biosynthetic process	GO:0031328	316	0.038	Human
maintenance of location	GO:0051235	73	0.038
g2 dna damage checkpoint	GO:0031572	69	0.038
rna splicing via transesterification reactions	GO:0000375	73	0.037
eye development	GO:0001654	323	0.036
negative regulation of cell cycle	GO:0045786	116	0.036	Human
vesicle mediated transport	GO:0016192	381	0.036
regulation of multicellular organismal development	GO:2000026	414	0.036
negative regulation of mitotic cell cycle	GO:0045930	109	0.036
regulation of cellular catabolic process	GO:0031329	157	0.036
negative regulation of cell cycle process	GO:0010948	109	0.035	Human
posttranscriptional regulation of gene expression	GO:0010608	145	0.035
regulation of programmed cell death	GO:0043067	152	0.035	Human
adult locomotory behavior	GO:0008344	76	0.035
negative regulation of organelle organization	GO:0010639	56	0.035
organelle fission	GO:0048285	340	0.034
regulation of protein modification process	GO:0031399	112	0.034	Human
regulation of developmental growth	GO:0048638	174	0.034
regulation of cellular protein metabolic process	GO:0032268	243	0.034	Human
cellular response to chemical stimulus	GO:0070887	199	0.034
positive regulation of biosynthetic process	GO:0009891	316	0.033	Human
immune response regulating signaling pathway	GO:0002764	2	0.033
regulation of nuclear division	GO:0051783	58	0.033
neuronal stem cell maintenance	GO:0097150	4	0.033
leg disc development	GO:0035218	92	0.032
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.032
r7 cell differentiation	GO:0045466	43	0.032
positive regulation of response to stimulus	GO:0048584	323	0.032
cellular macromolecule localization	GO:0070727	220	0.032
regulation of mrna processing	GO:0050684	71	0.031
regulation of catalytic activity	GO:0050790	185	0.031	Human
organelle assembly	GO:0070925	198	0.031
salivary gland morphogenesis	GO:0007435	145	0.031
regulation of response to biotic stimulus	GO:0002831	63	0.030
eye morphogenesis	GO:0048592	260	0.030
synapse organization	GO:0050808	196	0.030
intracellular protein transport	GO:0006886	104	0.030
kidney development	GO:0001822	3	0.030
mitotic cell cycle phase transition	GO:0044772	138	0.030
single organism catabolic process	GO:0044712	228	0.030
alternative mrna splicing via spliceosome	GO:0000380	60	0.030
cellular ketone metabolic process	GO:0042180	24	0.030
cellular protein complex assembly	GO:0043623	71	0.030
exocrine system development	GO:0035272	162	0.029
hematopoietic progenitor cell differentiation	GO:0002244	1	0.029
regulation of meiosis	GO:0040020	3	0.029
organic substance catabolic process	GO:1901575	308	0.028
response to organic substance	GO:0010033	284	0.028
mapk cascade	GO:0000165	107	0.028
regulation of chromosome organization	GO:0033044	64	0.028
spermatid differentiation	GO:0048515	114	0.028
nucleobase containing compound catabolic process	GO:0034655	165	0.028
negative regulation of chromosome segregation	GO:0051985	14	0.028
response to other organism	GO:0051707	293	0.028
morphogenesis of an epithelium	GO:0002009	276	0.028
cellular amino acid metabolic process	GO:0006520	61	0.027
protein targeting to nucleus	GO:0044744	51	0.027
neuroblast proliferation	GO:0007405	74	0.027
defense response to other organism	GO:0098542	225	0.026
spinal cord development	GO:0021510	1	0.026
chromosome segregation	GO:0007059	157	0.026
single organism intracellular transport	GO:1902582	207	0.026
determination of adult lifespan	GO:0008340	137	0.026
protein transport	GO:0015031	155	0.026
cell proliferation involved in imaginal disc derived wing morphogenesis	GO:0090255	2	0.026
negative regulation of epithelial cell proliferation	GO:0050680	4	0.026
muscle cell differentiation	GO:0042692	103	0.026
taxis	GO:0042330	304	0.026
positive regulation of rna metabolic process	GO:0051254	271	0.026	Human
regulation of cell cycle process	GO:0010564	181	0.026	Human
i kappab phosphorylation	GO:0007252	3	0.025
positive regulation of organelle organization	GO:0010638	65	0.025
male gamete generation	GO:0048232	201	0.025
endocytosis	GO:0006897	310	0.025
response to biotic stimulus	GO:0009607	294	0.025
multicellular organism growth	GO:0035264	46	0.025
regulation of cellular amino acid metabolic process	GO:0006521	0	0.025
neurological system process	GO:0050877	358	0.025
kidney morphogenesis	GO:0060993	3	0.025
positive regulation of immune system process	GO:0002684	68	0.025
response to external biotic stimulus	GO:0043207	293	0.024
regulation of immune system process	GO:0002682	176	0.024
eye photoreceptor cell differentiation	GO:0001754	145	0.024
regulation of cellular component biogenesis	GO:0044087	201	0.024
protein localization to nucleus	GO:0034504	55	0.024
protein localization	GO:0008104	284	0.024
phagocytosis	GO:0006909	215	0.024
carboxylic acid metabolic process	GO:0019752	92	0.024
positive regulation of proteolysis	GO:0045862	52	0.024
kidney epithelium development	GO:0072073	3	0.023
single organism nuclear import	GO:1902593	51	0.023
locomotory behavior	GO:0007626	176	0.023
dna integrity checkpoint	GO:0031570	81	0.023
positive regulation of macromolecule metabolic process	GO:0010604	405	0.023	Human
positive regulation of humoral immune response	GO:0002922	28	0.023
sister chromatid segregation	GO:0000819	92	0.023
molting cycle chitin based cuticle	GO:0007591	56	0.023
negative regulation of sequence specific dna binding transcription factor activity	GO:0043433	4	0.023
establishment of planar polarity	GO:0001736	87	0.023
single organism cellular localization	GO:1902580	180	0.023
compound eye photoreceptor cell differentiation	GO:0001751	140	0.023
regulation of autophagy	GO:0010506	62	0.023
cell cycle checkpoint	GO:0000075	95	0.023
positive regulation of protein metabolic process	GO:0051247	128	0.023
positive regulation of cellular component organization	GO:0051130	156	0.023
regulation of stress activated mapk cascade	GO:0032872	41	0.022
cell death	GO:0008219	279	0.022	Human
aging	GO:0007568	143	0.022
cellular response to organic substance	GO:0071310	132	0.022
nephron tubule morphogenesis	GO:0072078	3	0.022
negative regulation of developmental process	GO:0051093	201	0.022
regulation of apoptotic process	GO:0042981	130	0.022	Human
neuron projection guidance	GO:0097485	241	0.022
protein phosphorylation	GO:0006468	169	0.021	Human
regulation of i kappab kinase nf kappab signaling	GO:0043122	2	0.021
establishment or maintenance of cell polarity	GO:0007163	167	0.021
positive regulation of nf kappab import into nucleus	GO:0042346	1	0.021
regulation of wnt signaling pathway	GO:0030111	68	0.021
regulation of ras protein signal transduction	GO:0046578	93	0.021
positive regulation of phosphate metabolic process	GO:0045937	139	0.021
regulation of alternative mrna splicing via spliceosome	GO:0000381	60	0.021
immune response activating signal transduction	GO:0002757	2	0.020
mitotic dna integrity checkpoint	GO:0044774	75	0.020
regulation of organ formation	GO:0003156	3	0.020
positive regulation of programmed cell death	GO:0043068	62	0.020	Human
stem cell differentiation	GO:0048863	117	0.020
heterocycle catabolic process	GO:0046700	166	0.020
negative regulation of gene expression epigenetic	GO:0045814	77	0.020
adult behavior	GO:0030534	137	0.020
nuclear transport	GO:0051169	72	0.020
embryonic morphogenesis	GO:0048598	206	0.020
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.020
imaginal disc pattern formation	GO:0007447	91	0.020
regulation of multicellular organism growth	GO:0040014	40	0.020
defense response to bacterium	GO:0042742	178	0.019
negative regulation of sister chromatid segregation	GO:0033046	13	0.019
mrna processing	GO:0006397	104	0.019
intracellular transport	GO:0046907	228	0.019
regulation of cellular amine metabolic process	GO:0033238	3	0.019
protein import into nucleus	GO:0006606	51	0.019
positive regulation of macroautophagy	GO:0016239	8	0.019
axon development	GO:0061564	297	0.019
negative regulation of cellular component organization	GO:0051129	108	0.019
mitotic cell cycle embryonic	GO:0045448	38	0.019
positive regulation of phosphorylation	GO:0042327	87	0.019
germ line stem cell maintenance	GO:0030718	50	0.019
mitotic nuclear division	GO:0007067	213	0.019
negative regulation of stem cell differentiation	GO:2000737	8	0.018
regulation of cellular response to stress	GO:0080135	89	0.018
heart morphogenesis	GO:0003007	32	0.018
stem cell fate commitment	GO:0048865	25	0.018
nephron epithelium development	GO:0072009	3	0.018
nuclear division	GO:0000280	332	0.018
cytoplasmic transport	GO:0016482	130	0.018
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.018	Human
regulation of establishment of planar polarity	GO:0090175	22	0.018
asymmetric cell division	GO:0008356	37	0.018
cell fate specification	GO:0001708	71	0.018
mitotic spindle organization	GO:0007052	220	0.018
spindle organization	GO:0007051	253	0.018
regulation of cell cycle	GO:0051726	291	0.018	Human
cellular protein localization	GO:0034613	160	0.018
regulation of protein complex assembly	GO:0043254	42	0.018
monocarboxylic acid transport	GO:0015718	3	0.018
nephron tubule development	GO:0072080	3	0.018
embryo development ending in birth or egg hatching	GO:0009792	152	0.017
organic cyclic compound catabolic process	GO:1901361	168	0.017
positive regulation of cellular protein metabolic process	GO:0032270	118	0.017
regulation of phosphorus metabolic process	GO:0051174	210	0.017	Human
endomembrane system organization	GO:0010256	119	0.017
cell migration	GO:0016477	238	0.017
endoderm formation	GO:0001706	3	0.017
positive regulation of molecular function	GO:0044093	136	0.017
positive regulation of developmental process	GO:0051094	143	0.017
organelle localization	GO:0051640	148	0.017
positive regulation of cellular component biogenesis	GO:0044089	80	0.017
positive regulation of autophagy	GO:0010508	21	0.017
catabolic process	GO:0009056	409	0.017
peptidyl amino acid modification	GO:0018193	105	0.017
activation of innate immune response	GO:0002218	4	0.017
generation of precursor metabolites and energy	GO:0006091	42	0.017
epithelial cell differentiation	GO:0030855	322	0.016
mitotic sister chromatid segregation	GO:0000070	87	0.016
synaptic transmission	GO:0007268	288	0.016
positive regulation of ras protein signal transduction	GO:0046579	43	0.016
regulation of cell death	GO:0010941	173	0.016	Human
mitotic sister chromatid separation	GO:0051306	30	0.016
positive regulation of transcription dna templated	GO:0045893	266	0.016	Human
hormone biosynthetic process	GO:0042446	20	0.016
regulation of jnk cascade	GO:0046328	40	0.016
cell growth	GO:0016049	108	0.016
response to ecdysone	GO:0035075	34	0.016
cellular response to transforming growth factor beta stimulus	GO:0071560	18	0.016
innate immune response	GO:0045087	144	0.016
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.016
positive regulation of multicellular organismal process	GO:0051240	143	0.016
forebrain development	GO:0030900	2	0.016
regulation of neuroblast proliferation	GO:1902692	34	0.016
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.016
somatic stem cell maintenance	GO:0035019	14	0.016
organic substance transport	GO:0071702	257	0.016
biological adhesion	GO:0022610	138	0.016
response to organic cyclic compound	GO:0014070	89	0.016
muscle cell development	GO:0055001	50	0.015
response to monosaccharide	GO:0034284	4	0.015
regulation of immune response	GO:0050776	118	0.015
response to lipopolysaccharide	GO:0032496	4	0.015
regulation of catabolic process	GO:0009894	170	0.015
immune response	GO:0006955	246	0.015
response to transforming growth factor beta	GO:0071559	18	0.015
regulation of defense response to bacterium	GO:1900424	30	0.015
immune effector process	GO:0002252	98	0.015
regulation of microtubule based process	GO:0032886	49	0.015
mitotic dna damage checkpoint	GO:0044773	74	0.015
regulation of stem cell differentiation	GO:2000736	14	0.015
bmp signaling pathway involved in malpighian tubule cell chemotaxis	GO:0061353	3	0.015
response to oxygen containing compound	GO:1901700	200	0.015
regulation of transport	GO:0051049	181	0.015
rna catabolic process	GO:0006401	37	0.015
response to endogenous stimulus	GO:0009719	119	0.015
positive regulation of stem cell differentiation	GO:2000738	3	0.015
mesenchymal cell development	GO:0014031	1	0.015
negative regulation of chromosome organization	GO:2001251	19	0.015
stem cell development	GO:0048864	79	0.014
regulation of cellular ketone metabolic process	GO:0010565	3	0.014
regulation of compound eye retinal cell programmed cell death	GO:0046669	18	0.014
humoral immune response	GO:0006959	117	0.014
negative regulation of cell differentiation	GO:0045596	143	0.014
mesenchymal cell differentiation	GO:0048762	1	0.014
developmental growth	GO:0048589	280	0.014
notch signaling pathway	GO:0007219	120	0.014
rna 3 end processing	GO:0031123	45	0.014
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.014
tissue homeostasis	GO:0001894	36	0.014
regulation of mapk cascade	GO:0043408	92	0.014
lamellipodium organization	GO:0097581	21	0.014
amine metabolic process	GO:0009308	12	0.014
carbohydrate derivative metabolic process	GO:1901135	217	0.014
detection of stimulus involved in sensory perception	GO:0050906	92	0.014
instar larval development	GO:0002168	55	0.014
regulation of intracellular transport	GO:0032386	64	0.014
organonitrogen compound metabolic process	GO:1901564	318	0.014
imaginal disc derived leg morphogenesis	GO:0007480	80	0.014
regulation of proteolysis	GO:0030162	87	0.013
regulation of protein modification by small protein conjugation or removal	GO:1903320	25	0.013
cell cycle arrest	GO:0007050	4	0.013	Human
regulation of developmental pigmentation	GO:0048070	24	0.013
regulation of lipid transport	GO:0032368	3	0.013
positive regulation of mitotic cell cycle	GO:0045931	34	0.013
developmental programmed cell death	GO:0010623	138	0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	38	0.013
negative regulation of cell communication	GO:0010648	223	0.013
dorsal ventral axis specification	GO:0009950	66	0.013
multicellular organismal aging	GO:0010259	140	0.013
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.013	Human
establishment of protein localization	GO:0045184	163	0.013
positive regulation of cell motility	GO:2000147	3	0.013
germarium derived egg chamber formation	GO:0007293	101	0.013
regulation of timing of cell differentiation	GO:0048505	1	0.013
tricarboxylic acid metabolic process	GO:0072350	1	0.013
axon guidance	GO:0007411	233	0.013
negative regulation of nervous system development	GO:0051961	92	0.013
imaginal disc derived wing margin morphogenesis	GO:0008587	41	0.013
positive regulation of response to external stimulus	GO:0032103	44	0.013
positive regulation of cell cycle process	GO:0090068	28	0.013
extrinsic apoptotic signaling pathway	GO:0097191	1	0.013
gland morphogenesis	GO:0022612	145	0.013
cellular response to growth factor stimulus	GO:0071363	30	0.013
histone methylation	GO:0016571	40	0.013
jnk cascade	GO:0007254	50	0.013
regulation of synapse structure and activity	GO:0050803	128	0.013
cell motility	GO:0048870	251	0.013
establishment of imaginal disc derived wing hair orientation	GO:0001737	24	0.013
regulation of protein polymerization	GO:0032271	28	0.013
regulation of apoptotic signaling pathway	GO:2001233	10	0.012
rna splicing via transesterification reactions with bulged adenosine as nucleophile	GO:0000377	73	0.012
regulation of synapse assembly	GO:0051963	94	0.012
multicellular organismal signaling	GO:0035637	12	0.012
regulation of defense response	GO:0031347	102	0.012
negative regulation of molecular function	GO:0044092	51	0.012	Human
methylation	GO:0032259	47	0.012
stem cell proliferation	GO:0072089	88	0.012
protein import	GO:0017038	55	0.012
skeletal muscle organ development	GO:0060538	48	0.012
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	65	0.012
negative regulation of protein metabolic process	GO:0051248	85	0.012	Human
compound eye retinal cell programmed cell death	GO:0046667	23	0.012
muscle system process	GO:0003012	21	0.012
signal transduction by phosphorylation	GO:0023014	107	0.012
regulation of rna splicing	GO:0043484	69	0.012
endodermal cell fate commitment	GO:0001711	3	0.012
mitotic g2 dna damage checkpoint	GO:0007095	69	0.012
apoptotic signaling pathway	GO:0097190	27	0.012
nuclear import	GO:0051170	51	0.012
startle response	GO:0001964	16	0.012
neuromuscular process	GO:0050905	21	0.012
dna metabolic process	GO:0006259	227	0.012
regulation of actin cytoskeleton organization	GO:0032956	42	0.012
chemotaxis	GO:0006935	249	0.012
positive regulation of jun kinase activity	GO:0043507	4	0.012
aggressive behavior	GO:0002118	63	0.012
positive regulation of cytoskeleton organization	GO:0051495	21	0.011
planar cell polarity pathway involved in axis elongation	GO:0003402	3	0.011
microtubule bundle formation	GO:0001578	27	0.011
cellular amide metabolic process	GO:0043603	80	0.011
positive regulation of apoptotic process	GO:0043065	47	0.011	Human
nf kappab import into nucleus	GO:0042348	1	0.011
innate immune response in mucosa	GO:0002227	2	0.011
regulation of immune effector process	GO:0002697	52	0.011
larval locomotory behavior	GO:0008345	27	0.011
epithelial structure maintenance	GO:0010669	17	0.011
membrane organization	GO:0061024	112	0.011
cell cycle phase transition	GO:0044770	140	0.011
positive regulation of stress activated mapk cascade	GO:0032874	17	0.011
positive regulation of erk1 and erk2 cascade	GO:0070374	36	0.011
purine ribonucleotide metabolic process	GO:0009150	145	0.011
female meiosis chromosome segregation	GO:0016321	33	0.011
anterior posterior pattern specification	GO:0009952	136	0.011
regulation of protein catabolic process	GO:0042176	55	0.011
positive regulation of rna biosynthetic process	GO:1902680	266	0.011	Human
negative regulation of photoreceptor cell differentiation	GO:0046533	8	0.011
protein localization to organelle	GO:0033365	82	0.011
head development	GO:0060322	135	0.011
jak stat cascade	GO:0007259	49	0.011
regulation of hormone levels	GO:0010817	40	0.011
cellular nitrogen compound catabolic process	GO:0044270	165	0.010
spermatid development	GO:0007286	98	0.010
stress activated protein kinase signaling cascade	GO:0031098	55	0.010
cell fate determination	GO:0001709	91	0.010
positive regulation of production of molecular mediator of immune response	GO:0002702	28	0.010
negative regulation of signaling	GO:0023057	219	0.010
macromolecule methylation	GO:0043414	45	0.010
camera type eye development	GO:0043010	4	0.010
regulation of antibacterial peptide biosynthetic process	GO:0002808	22	0.010
nuclear envelope organization	GO:0006998	7	0.010
dna templated transcriptional preinitiation complex assembly	GO:0070897	20	0.010
regulation of phosphatase activity	GO:0010921	3	0.010
limb morphogenesis	GO:0035108	1	0.010
compound eye photoreceptor development	GO:0042051	78	0.010
response to extracellular stimulus	GO:0009991	116	0.010

crp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.027
disease of cellular proliferation	DOID:14566	0.020
neurodegenerative disease	DOID:1289	0.016
nervous system disease	DOID:863	0.016
motor neuron disease	DOID:231	0.016
central nervous system disease	DOID:331	0.016
disease of metabolism	DOID:0014667	0.015
musculoskeletal system disease	DOID:17	0.013
cancer	DOID:162	0.013
organ system cancer	DOID:0050686	0.013

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