IMP: Integrative Multi-species Prediction

Drosophila melanogaster

42 known processes

pita (Dmel_CG3941)

CG3941 gene product from transcript CG3941-RA

(Aliases: CG3941,Dmel\CG3941,spdk)

FLYBASE: FBgn0034878
Entrez: 37730
UniProtKB: Q9W1N1
UniProtKB: Q95RQ8

Process Predictions
Disease Predictions

pita biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
oocyte axis specification	GO:0007309	108	0.993
oocyte differentiation	GO:0009994	145	0.989
oocyte development	GO:0048599	124	0.988
pole plasm oskar mrna localization	GO:0045451	46	0.982
centrosome cycle	GO:0007098	137	0.979
cell maturation	GO:0048469	144	0.973
anterior posterior pattern specification	GO:0009952	136	0.971
oocyte anterior posterior axis specification	GO:0007314	72	0.967
rna localization	GO:0006403	115	0.954
mitotic sister chromatid segregation	GO:0000070	87	0.943
organelle fission	GO:0048285	340	0.942
pole plasm mrna localization	GO:0019094	49	0.940
mitotic nuclear division	GO:0007067	213	0.907
oocyte construction	GO:0007308	112	0.889
sister chromatid segregation	GO:0000819	92	0.849
intracellular mrna localization involved in anterior posterior axis specification	GO:0060811	53	0.830
intracellular mrna localization	GO:0008298	66	0.779
mitotic spindle organization	GO:0007052	220	0.773
anterior posterior axis specification	GO:0009948	109	0.770
pole plasm assembly	GO:0007315	61	0.742
single organism cellular localization	GO:1902580	180	0.736
tripartite regional subdivision	GO:0007351	103	0.697
developmental maturation	GO:0021700	172	0.696
anterior posterior axis specification embryo	GO:0008595	103	0.680
microtubule organizing center organization	GO:0031023	168	0.609
nuclear division	GO:0000280	332	0.602
cytoplasm organization	GO:0007028	64	0.592
embryonic axis specification	GO:0000578	107	0.515
segmentation	GO:0035282	207	0.497
regionalization	GO:0003002	416	0.437
dna metabolic process	GO:0006259	227	0.436
regulation of mitosis	GO:0007088	56	0.431
intracellular mrna localization involved in pattern specification process	GO:0060810	56	0.418
cellular macromolecule localization	GO:0070727	220	0.418
blastoderm segmentation	GO:0007350	159	0.408
axis specification	GO:0009798	167	0.395
maternal determination of anterior posterior axis embryo	GO:0008358	74	0.388
positive regulation of macromolecule metabolic process	GO:0010604	405	0.380
mitotic chromosome condensation	GO:0007076	22	0.338
pole plasm rna localization	GO:0007316	52	0.320
spindle organization	GO:0007051	253	0.320
establishment of localization in cell	GO:0051649	402	0.310
positive regulation of transcription dna templated	GO:0045893	266	0.305
centrosome organization	GO:0051297	163	0.264
phosphorylation	GO:0016310	294	0.262
centrosome duplication	GO:0051298	121	0.248
chromosome localization	GO:0050000	20	0.237
metaphase plate congression	GO:0051310	19	0.233
metaphase anaphase transition of cell cycle	GO:0044784	28	0.230
establishment of chromosome localization	GO:0051303	20	0.223
spindle assembly involved in mitosis	GO:0090307	50	0.207
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.200
chromosome segregation	GO:0007059	157	0.193
embryonic pattern specification	GO:0009880	174	0.182
regulation of cell proliferation	GO:0042127	163	0.168
regulation of mitotic cell cycle	GO:0007346	190	0.168
cell cycle dna replication	GO:0044786	23	0.158
chromosome condensation	GO:0030261	41	0.154
reproductive structure development	GO:0048608	74	0.149
regulation of protein metabolic process	GO:0051246	256	0.138
dna replication	GO:0006260	48	0.135
chromosome organization	GO:0051276	360	0.131
eggshell formation	GO:0030703	105	0.117
regulation of cell cycle	GO:0051726	291	0.109
cell proliferation	GO:0008283	299	0.105
positive regulation of gene expression	GO:0010628	290	0.102
regulation of cell division	GO:0051302	72	0.101
cellular catabolic process	GO:0044248	372	0.099
regulation of cellular component biogenesis	GO:0044087	201	0.096
cell division	GO:0051301	248	0.095
death	GO:0016265	284	0.092
macromolecular complex assembly	GO:0065003	256	0.090
organelle localization	GO:0051640	148	0.089
actin filament organization	GO:0007015	126	0.088
microtubule cytoskeleton organization involved in mitosis	GO:1902850	52	0.088
mitotic sister chromatid separation	GO:0051306	30	0.078
regulation of localization	GO:0032879	275	0.077
protein polymerization	GO:0051258	42	0.077
gonad development	GO:0008406	50	0.075
regulation of cell cycle process	GO:0010564	181	0.074
gland morphogenesis	GO:0022612	145	0.074
humoral immune response	GO:0006959	117	0.074
cellular macromolecular complex assembly	GO:0034622	153	0.072
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.072
cell death	GO:0008219	279	0.071
chorion containing eggshell formation	GO:0007304	105	0.071
regulation of chromosome segregation	GO:0051983	32	0.068
cellular protein complex assembly	GO:0043623	71	0.064
organic substance catabolic process	GO:1901575	308	0.063
modification dependent protein catabolic process	GO:0019941	78	0.063
cellular ketone metabolic process	GO:0042180	24	0.062
catabolic process	GO:0009056	409	0.060
protein complex assembly	GO:0006461	200	0.059
axon development	GO:0061564	297	0.058
regulation of cellular protein metabolic process	GO:0032268	243	0.055
gliogenesis	GO:0042063	80	0.055
asymmetric protein localization involved in cell fate determination	GO:0045167	9	0.054
regulation of mitotic sister chromatid separation	GO:0010965	28	0.050
regulation of proteolysis	GO:0030162	87	0.049
maternal specification of dorsal ventral axis oocyte germ line encoded	GO:0007311	4	0.048
dna packaging	GO:0006323	91	0.047
dna conformation change	GO:0071103	105	0.046
regulation of multicellular organismal development	GO:2000026	414	0.046
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.046
positive regulation of cellular component organization	GO:0051130	156	0.044
regulation of metaphase anaphase transition of cell cycle	GO:1902099	26	0.044
protein phosphorylation	GO:0006468	169	0.043
cytoplasmic transport	GO:0016482	130	0.042
intracellular signal transduction	GO:0035556	300	0.041
positive regulation of cell cycle process	GO:0090068	28	0.041
regulation of cellular amine metabolic process	GO:0033238	3	0.040
rhythmic process	GO:0048511	106	0.039
regulation of nucleocytoplasmic transport	GO:0046822	35	0.039
single organism intracellular transport	GO:1902582	207	0.038
autophagic cell death	GO:0048102	83	0.037
axonogenesis	GO:0007409	290	0.036
learning	GO:0007612	75	0.036
regulation of organelle organization	GO:0033043	196	0.036
histone lysine demethylation	GO:0070076	6	0.036
phagocytosis	GO:0006909	215	0.036
positive regulation of cellular component biogenesis	GO:0044089	80	0.035
circadian rhythm	GO:0007623	105	0.035
positive regulation of intracellular signal transduction	GO:1902533	116	0.035
organic acid metabolic process	GO:0006082	103	0.035
neurological system process	GO:0050877	358	0.034
salivary gland development	GO:0007431	162	0.033
centrosome separation	GO:0051299	20	0.032
reproductive system development	GO:0061458	74	0.032
sex differentiation	GO:0007548	81	0.032
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.031
regulation of transport	GO:0051049	181	0.030
open tracheal system development	GO:0007424	204	0.030
g2 dna damage checkpoint	GO:0031572	69	0.030
regulation of cellular localization	GO:0060341	136	0.029
regulation of protein transport	GO:0051223	57	0.029
positive regulation of mitotic sister chromatid separation	GO:1901970	10	0.029
single organism behavior	GO:0044708	391	0.028
positive regulation of response to stimulus	GO:0048584	323	0.028
regulation of mitotic metaphase anaphase transition	GO:0030071	26	0.027
regulation of cellular catabolic process	GO:0031329	157	0.027
regulation of cellular amino acid metabolic process	GO:0006521	0	0.027
cellular response to peptide	GO:1901653	28	0.026
kinetochore organization	GO:0051383	9	0.026
regulation of phosphorylation	GO:0042325	147	0.026
single organism catabolic process	GO:0044712	228	0.026
germarium derived egg chamber formation	GO:0007293	101	0.025
positive regulation of metaphase anaphase transition of cell cycle	GO:1902101	10	0.024
macromolecule catabolic process	GO:0009057	161	0.024
body morphogenesis	GO:0010171	2	0.024
cellular macromolecule catabolic process	GO:0044265	136	0.024
positive regulation of rna biosynthetic process	GO:1902680	266	0.023
establishment of organelle localization	GO:0051656	122	0.023
mitotic metaphase plate congression	GO:0007080	13	0.023
intracellular transport	GO:0046907	228	0.023
protein complex biogenesis	GO:0070271	201	0.023
regulation of nuclear division	GO:0051783	58	0.022
branching involved in open tracheal system development	GO:0060446	45	0.022
regulation of cell cycle phase transition	GO:1901987	130	0.022
aromatic compound catabolic process	GO:0019439	166	0.022
regulation of cellular ketone metabolic process	GO:0010565	3	0.022
negative regulation of response to stimulus	GO:0048585	258	0.022
tissue death	GO:0016271	102	0.022
positive regulation of rna metabolic process	GO:0051254	271	0.021
protein transport	GO:0015031	155	0.021
karyosome formation	GO:0030717	22	0.021
regulation of programmed cell death	GO:0043067	152	0.021
cellular protein modification process	GO:0006464	438	0.021
nucleocytoplasmic transport	GO:0006913	72	0.021
spindle assembly	GO:0051225	80	0.021
single organism biosynthetic process	GO:0044711	206	0.021
cell cycle phase transition	GO:0044770	140	0.020
metaphase anaphase transition of mitotic cell cycle	GO:0007091	28	0.020
regulation of cell development	GO:0060284	215	0.020
mitotic cell cycle checkpoint	GO:0007093	88	0.019
regulation of hemocyte proliferation	GO:0035206	37	0.019
nuclear transport	GO:0051169	72	0.019
positive regulation of biosynthetic process	GO:0009891	316	0.019
positive regulation of mitotic cell cycle	GO:0045931	34	0.019
regulation of chromosome organization	GO:0033044	64	0.018
oocyte microtubule cytoskeleton organization	GO:0016325	35	0.018
growth	GO:0040007	359	0.018
response to nutrient levels	GO:0031667	114	0.018
regulation of neurogenesis	GO:0050767	158	0.017
small molecule metabolic process	GO:0044281	305	0.017
salivary gland morphogenesis	GO:0007435	145	0.017
programmed cell death	GO:0012501	257	0.017
homeostatic process	GO:0042592	199	0.017
gland development	GO:0048732	191	0.017
pole cell development	GO:0007277	26	0.017
dna damage checkpoint	GO:0000077	78	0.017
nuclear import	GO:0051170	51	0.017
cellular amino acid metabolic process	GO:0006520	61	0.016
positive regulation of cellular biosynthetic process	GO:0031328	316	0.016
regulation of apoptotic process	GO:0042981	130	0.016
negative regulation of cellular component organization	GO:0051129	108	0.016
cellular response to oxygen containing compound	GO:1901701	79	0.016
negative regulation of erk1 and erk2 cascade	GO:0070373	3	0.016
muscle structure development	GO:0061061	224	0.015
negative regulation of mitotic cell cycle	GO:0045930	109	0.015
negative regulation of intrinsic apoptotic signaling pathway	GO:2001243	1	0.015
positive regulation of mitotic metaphase anaphase transition	GO:0045842	10	0.015
cellular response to peptide hormone stimulus	GO:0071375	28	0.015
regulation of circadian rhythm	GO:0042752	49	0.014
regulation of intracellular signal transduction	GO:1902531	236	0.014
cellular nitrogen compound catabolic process	GO:0044270	165	0.014
single organism nuclear import	GO:1902593	51	0.014
cellular response to insulin stimulus	GO:0032869	28	0.014
regulation of proteasomal protein catabolic process	GO:0061136	39	0.014
chromosome separation	GO:0051304	42	0.014
developmental programmed cell death	GO:0010623	138	0.014
organonitrogen compound metabolic process	GO:1901564	318	0.014
proteolysis involved in cellular protein catabolic process	GO:0051603	83	0.014
regulation of mapk cascade	GO:0043408	92	0.013
establishment or maintenance of cell polarity	GO:0007163	167	0.013
covalent chromatin modification	GO:0016569	106	0.013
cell cycle checkpoint	GO:0000075	95	0.013
carboxylic acid metabolic process	GO:0019752	92	0.013
histolysis	GO:0007559	102	0.013
male meiosis chromosome segregation	GO:0007060	10	0.012
dendrite morphogenesis	GO:0048813	199	0.012
female meiotic division	GO:0007143	70	0.012
syncytial blastoderm mitotic cell cycle	GO:0035186	21	0.012
regulation of ras protein signal transduction	GO:0046578	93	0.012
negative regulation of proteasomal ubiquitin dependent protein catabolic process	GO:0032435	16	0.012
regulation of protein export from nucleus	GO:0046825	3	0.012
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.012
positive regulation of signal transduction	GO:0009967	223	0.012
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.012
organic cyclic compound catabolic process	GO:1901361	168	0.012
ubiquitin dependent protein catabolic process	GO:0006511	78	0.011
extrinsic apoptotic signaling pathway	GO:0097191	1	0.011
peptidyl threonine modification	GO:0018210	3	0.011
negative regulation of protein metabolic process	GO:0051248	85	0.011
positive regulation of binding	GO:0051099	4	0.011
positive regulation of catabolic process	GO:0009896	105	0.011
development of primary sexual characteristics	GO:0045137	50	0.011
forebrain development	GO:0030900	2	0.011
neuron projection guidance	GO:0097485	241	0.011
peptidyl threonine phosphorylation	GO:0018107	2	0.011
muscle organ development	GO:0007517	127	0.011
regulation of cellular protein catabolic process	GO:1903362	44	0.011
photoreceptor cell fate commitment	GO:0046552	41	0.011
dendrite development	GO:0016358	204	0.010
protein localization	GO:0008104	284	0.010
negative regulation of gene expression	GO:0010629	387	0.010
axon guidance	GO:0007411	233	0.010
intracellular protein transport	GO:0006886	104	0.010
mitochondrial membrane organization	GO:0007006	3	0.010
genitalia development	GO:0048806	26	0.010
somatic stem cell division	GO:0048103	37	0.010
regulation of cell projection organization	GO:0031344	92	0.010

pita disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.016

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