Drosophila melanogaster

180 known processes

ebi (Dmel_CG4063)

CG4063 gene product from transcript CG4063-RA

(Aliases: CG4063,Ebi,l(2)k16213,Dmel\CG4063,Tb11,Tbl1)

ebi biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
photoreceptor cell differentiationGO:00465301700.974
protein modification processGO:00362114380.968
eye developmentGO:00016543230.954
compound eye developmentGO:00487493070.953
growthGO:00400073590.944
compound eye morphogenesisGO:00017452490.918
negative regulation of cellular metabolic processGO:00313243820.901
body morphogenesisGO:001017120.895
cellular protein modification processGO:00064644380.891
sensory organ morphogenesisGO:00905962600.891
regulation of cell differentiationGO:00455953020.859
compound eye photoreceptor cell differentiationGO:00017511400.852
positive regulation of macromolecule biosynthetic processGO:00105572830.849
Human Mouse
positive regulation of transcription dna templatedGO:00458932660.839
Human Mouse
cell proliferationGO:00082832990.831
regulation of growthGO:00400082330.823
response to radiationGO:00093141550.817
protein phosphorylationGO:00064681690.758
cell motilityGO:00488702510.756
eye morphogenesisGO:00485922600.746
positive regulation of biosynthetic processGO:00098913160.746
Human Mouse
positive regulation of developmental growthGO:0048639620.745
embryo development ending in birth or egg hatchingGO:00097921520.744
single organism cellular localizationGO:19025801800.722
positive regulation of nitrogen compound metabolic processGO:00511733540.708
Human Mouse
establishment of localization in cellGO:00516494020.669
cellular response to dna damage stimulusGO:00069742230.654
stem cell differentiationGO:00488631170.647
tube developmentGO:00352952440.639
positive regulation of cellular biosynthetic processGO:00313283160.632
Human Mouse
developmental growthGO:00485892800.630
taxisGO:00423303040.612
localization of cellGO:00516742570.599
regulation of developmental growthGO:00486381740.574
enzyme linked receptor protein signaling pathwayGO:00071671790.551
regulation of transcription from rna polymerase ii promoterGO:00063573780.543
positive regulation of nucleobase containing compound metabolic processGO:00459353320.513
Human Mouse
positive regulation of gene expressionGO:00106282900.503
Human Mouse
regulation of multicellular organism growthGO:0040014400.499
cellular macromolecule localizationGO:00707272200.497
positive regulation of multicellular organism growthGO:0040018210.474
nucleocytoplasmic transportGO:0006913720.465
organic substance transportGO:00717022570.459
positive regulation of rna metabolic processGO:00512542710.450
Human Mouse
transcription from rna polymerase ii promoterGO:00063663680.431
regulation of cellular protein metabolic processGO:00322682430.429
positive regulation of nucleic acid templated transcriptionGO:19035082660.423
Human Mouse
response to abiotic stimulusGO:00096283410.395
negative regulation of gene expressionGO:00106293870.392
positive regulation of cell communicationGO:00106472500.385
programmed cell deathGO:00125012570.377
notch signaling pathwayGO:00072191200.374
appendage morphogenesisGO:00351073970.372
determination of adult lifespanGO:00083401370.368
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.353
Human Mouse
tissue morphogenesisGO:00487292970.348
multicellular organism growthGO:0035264460.336
Mouse
regulation of cell proliferationGO:00421271630.324
positive regulation of rna biosynthetic processGO:19026802660.318
Human Mouse
gastrulationGO:0007369700.311
imaginal disc derived wing morphogenesisGO:00074763370.310
negative regulation of multicellular organismal processGO:00512411420.308
regulation of notch signaling pathwayGO:00085931000.306
protein localization to organelleGO:0033365820.302
positive regulation of developmental processGO:00510941430.297
imaginal disc derived appendage morphogenesisGO:00351143950.263
regulation of cell deathGO:00109411730.256
multicellular organismal reproductive behaviorGO:00330571100.253
cytoplasmic transportGO:00164821300.253
regulation of cell cycle processGO:00105641810.251
mitotic cell cycle phase transitionGO:00447721380.249
cellular response to endogenous stimulusGO:0071495800.244
cell fate specificationGO:0001708710.240
regulation of molecular functionGO:00650092170.239
epithelial cell developmentGO:00020642740.237
mitotic g2 m transition checkpointGO:0044818700.236
compound eye photoreceptor fate commitmentGO:0001752360.235
histone modificationGO:00165701060.235
protein localizationGO:00081042840.232
regulation of cellular localizationGO:00603411360.231
regulation of protein metabolic processGO:00512462560.231
wing disc morphogenesisGO:00074723440.228
negative regulation of molecular functionGO:0044092510.227
stem cell maintenanceGO:0019827670.225
epithelial cell differentiationGO:00308553220.224
positive regulation of multicellular organismal processGO:00512401430.222
phosphorylationGO:00163102940.222
reproductive system developmentGO:0061458740.207
intracellular signal transductionGO:00355563000.206
mitotic spindle organizationGO:00070522200.203
negative regulation of signalingGO:00230572190.198
nuclear transportGO:0051169720.196
protein ubiquitinationGO:0016567700.192
response to external biotic stimulusGO:00432072930.182
digestive system developmentGO:00551231490.181
tube morphogenesisGO:00352391910.180
eye photoreceptor cell differentiationGO:00017541450.179
deathGO:00162652840.176
response to organic substanceGO:00100332840.173
Mouse
membrane organizationGO:00610241120.173
regulation of anatomical structure morphogenesisGO:00226032420.171
cell migrationGO:00164772380.167
cell adhesionGO:00071551360.164
regulation of nervous system developmentGO:00519602480.163
response to light stimulusGO:00094161240.158
positive regulation of response to stimulusGO:00485843230.157
cellular protein localizationGO:00346131600.156
regulation of organ morphogenesisGO:2000027780.156
agingGO:00075681430.151
multicellular organismal agingGO:00102591400.150
regulation of cell cycleGO:00517262910.144
protein transportGO:00150311550.143
stem cell developmentGO:0048864790.135
positive regulation of signalingGO:00230562430.133
biological adhesionGO:00226101380.131
regulation of phosphorylationGO:00423251470.129
establishment of protein localizationGO:00451841630.128
tracheal outgrowth open tracheal systemGO:0007426180.128
regulation of mitotic cell cycleGO:00073461900.120
muscle structure developmentGO:00610612240.116
negative regulation of rna biosynthetic processGO:19026792400.113
receptor mediated endocytosisGO:0006898210.113
heart developmentGO:0007507820.113
negative regulation of signal transductionGO:00099682060.112
positive regulation of cell proliferationGO:0008284470.112
post embryonic appendage morphogenesisGO:00351203850.110
molting cycleGO:0042303560.109
negative regulation of cell cycleGO:00457861160.109
cell deathGO:00082192790.107
regulation of mrna metabolic processGO:1903311720.107
negative regulation of mitotic cell cycleGO:00459301090.106
single organism intracellular transportGO:19025822070.103
small molecule metabolic processGO:00442813050.102
Mouse
positive regulation of signal transductionGO:00099672230.101
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.100
dorsal ventral pattern formationGO:00099531330.097
amine metabolic processGO:0009308120.096
digestive tract developmentGO:00485651490.096
cellular response to chemical stimulusGO:00708871990.095
single organism nuclear importGO:1902593510.094
negative regulation of response to stimulusGO:00485852580.093
rna processingGO:00063961470.092
cellular amine metabolic processGO:0044106120.092
imaginal disc derived appendage developmentGO:00487373990.091
positive regulation of growthGO:0045927750.091
response to extracellular stimulusGO:00099911160.090
Mouse
positive regulation of macromolecule metabolic processGO:00106044050.090
regulation of neurogenesisGO:00507671580.085
cellular response to organic substanceGO:00713101320.085
circulatory system developmentGO:0072359820.083
regulation of sister chromatid cohesionGO:000706320.083
development of primary sexual characteristicsGO:0045137500.083
protein localization to nucleusGO:0034504550.083
multi multicellular organism processGO:00447061230.082
vesicle mediated transportGO:00161923810.080
embryonic morphogenesisGO:00485982060.077
regulation of cytoplasmic transportGO:1903649470.075
kidney developmentGO:000182230.075
negative regulation of cell proliferationGO:0008285690.074
regulation of cellular amino acid metabolic processGO:000652100.073
multi organism reproductive behaviorGO:00447051210.072
regulation of protein modification processGO:00313991120.071
embryonic organ developmentGO:0048568500.071
neuron recognitionGO:00080381010.071
regulation of intracellular transportGO:0032386640.071
negative regulation of catalytic activityGO:0043086420.070
negative regulation of nitrogen compound metabolic processGO:00511722650.069
cardiovascular system developmentGO:0072358820.068
intracellular protein transportGO:00068861040.068
defense response to other organismGO:00985422250.068
cellular catabolic processGO:00442483720.066
Mouse
response to biotic stimulusGO:00096072940.065
mitotic g2 dna damage checkpointGO:0007095690.065
muscle organ developmentGO:00075171270.065
protein modification by small protein conjugation or removalGO:00706471060.065
organophosphate metabolic processGO:00196371950.064
Mouse
chromatin organizationGO:00063252070.063
response to nitrogen compoundGO:1901698900.063
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.063
morphogenesis of an epitheliumGO:00020092760.062
regulation of kinase activityGO:0043549530.062
appendage developmentGO:00487364010.062
negative regulation of cell communicationGO:00106482230.062
gonad developmentGO:0008406500.061
response to oxygen containing compoundGO:19017002000.061
dorsal ventral axis specification ovarian follicular epitheliumGO:0008069130.060
regulation of cellular amine metabolic processGO:003323830.060
histone h3 acetylationGO:0043966110.059
regulation of localizationGO:00328792750.058
negative regulation of phosphate metabolic processGO:0045936450.057
cell substrate adhesionGO:0031589100.057
proteolysisGO:00065081920.057
Human Mouse
renal system developmentGO:0072001720.056
peptidyl amino acid modificationGO:00181931050.055
imaginal disc derived leg morphogenesisGO:0007480800.054
regulation of cellular response to stressGO:0080135890.052
g2 dna damage checkpointGO:0031572690.052
establishment of mitotic spindle localizationGO:0040001170.052
cellular response to oxygen containing compoundGO:1901701790.052
mrna processingGO:00063971040.052
regulation of cellular catabolic processGO:00313291570.051
negative regulation of cell deathGO:0060548810.051
regulation of cell adhesionGO:0030155270.051
hindbrain developmentGO:003090220.050
positive regulation of nucleocytoplasmic transportGO:0046824240.050
nuclear migrationGO:0007097200.050
regulation of protein phosphorylationGO:0001932640.050
immune system processGO:00023763470.050
intracellular receptor signaling pathwayGO:0030522190.049
negative regulation of developmental processGO:00510932010.049
regulation of protein localizationGO:0032880760.048
protein localization to chromatinGO:007116830.048
cellular nitrogen compound catabolic processGO:00442701650.047
epidermal growth factor receptor signaling pathwayGO:0007173580.047
negative regulation of macromolecule biosynthetic processGO:00105582700.046
rna splicingGO:0008380830.045
larval developmentGO:00021641040.045
cell cycle g1 s phase transitionGO:0044843310.042
chromatin assembly or disassemblyGO:0006333520.042
regulation of response to dna damage stimulusGO:2001020230.042
regulation of transportGO:00510491810.041
cellular lipid metabolic processGO:0044255830.041
Mouse
reproductive structure developmentGO:0048608740.041
positive regulation of phosphorylationGO:0042327870.041
dorsal closureGO:0007391790.041
regulation of epidermal growth factor receptor signaling pathwayGO:0042058420.041
cuticle developmentGO:0042335860.040
antimicrobial humoral responseGO:0019730990.040
positive regulation of protein phosphorylationGO:0001934340.040
sex differentiationGO:0007548810.040
regulation of embryonic developmentGO:0045995680.040
establishment or maintenance of cell polarityGO:00071631670.039
negative regulation of transcription factor import into nucleusGO:004299240.038
immune responseGO:00069552460.037
establishment of mitotic spindle orientationGO:0000132130.037
spindle organizationGO:00070512530.037
negative regulation of protein metabolic processGO:0051248850.037
negative regulation of cellular protein metabolic processGO:0032269850.037
eye antennal disc developmentGO:0035214600.036
reproductive behaviorGO:00190981220.036
negative regulation of programmed cell deathGO:0043069720.036
neural precursor cell proliferationGO:0061351750.036
morphogenesis of embryonic epitheliumGO:0016331940.036
regulation of establishment of protein localizationGO:0070201610.035
neuroblast proliferationGO:0007405740.035
dendrite morphogenesisGO:00488131990.035
attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregationGO:005131610.035
negative regulation of rna metabolic processGO:00512532510.035
meiotic cell cycleGO:00513211710.035
embryonic cleavageGO:004001650.035
multi organism behaviorGO:00517051750.034
gland developmentGO:00487321910.034
negative regulation of nucleic acid templated transcriptionGO:19035072400.034
central nervous system developmentGO:00074172010.034
dna integrity checkpointGO:0031570810.034
regulation of programmed cell deathGO:00430671520.034
protein importGO:0017038550.034
mrna metabolic processGO:00160711240.034
regulation of phosphate metabolic processGO:00192202100.034
Mouse
oxoacid metabolic processGO:00434361030.033
brain developmentGO:00074201200.033
histone acetylationGO:0016573380.033
leg disc developmentGO:0035218920.033
ovarian follicle cell developmentGO:00307072480.032
nuclear importGO:0051170510.032
positive regulation of cell cycle g2 m phase transitionGO:190275120.031
somatic stem cell maintenanceGO:0035019140.031
imaginal disc derived wing vein morphogenesisGO:0008586440.031
intracellular transportGO:00469072280.030
protein maturationGO:0051604710.030
positive regulation of cell adhesionGO:0045785100.030
cytokinetic processGO:0032506270.030
cell cycle phase transitionGO:00447701400.030
regulation of chromatin organizationGO:1902275320.030
regulation of protein kinase activityGO:0045859510.030
establishment of protein localization to organelleGO:0072594620.030
regulation of catalytic activityGO:00507901850.029
leg disc morphogenesisGO:0007478800.029
neuron projection guidanceGO:00974852410.029
mushroom body developmentGO:0016319700.028
protein import into nucleusGO:0006606510.028
regulation of stress activated mapk cascadeGO:0032872410.028
mitotic dna integrity checkpointGO:0044774750.028
regulation of phosphorus metabolic processGO:00511742100.028
Mouse
regulation of cellular ketone metabolic processGO:001056530.028
organelle fissionGO:00482853400.028
chromatin modificationGO:00165681470.027
digestive tract morphogenesisGO:00485461270.027
sensory perceptionGO:00076001960.027
Human
centrosome cycleGO:00070981370.027
chromosome organizationGO:00512763600.026
regulation of nucleocytoplasmic transportGO:0046822350.026
secretionGO:00469031090.026
i kappab phosphorylationGO:000725230.026
matingGO:00076181200.026
positive regulation of i kappab kinase nf kappab signalingGO:004312310.025
cell divisionGO:00513012480.025
endocytosisGO:00068973100.025
positive regulation of protein kinase activityGO:0045860250.025
photoreceptor cell fate commitmentGO:0046552410.025
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.025
mrna splicing via spliceosomeGO:0000398730.025
negative regulation of intrinsic apoptotic signaling pathwayGO:200124310.024
lipid biosynthetic processGO:0008610460.024
carboxylic acid metabolic processGO:0019752920.024
organ growthGO:0035265560.024
regionalizationGO:00030024160.024
intracellular steroid hormone receptor signaling pathwayGO:0030518120.023
dendrite developmentGO:00163582040.023
gliogenesisGO:0042063800.023
regulation of apoptotic processGO:00429811300.023
signal transduction in response to dna damageGO:004277030.022
negative regulation of apoptotic processGO:0043066630.022
memoryGO:0007613940.022
regulation of locomotionGO:0040012420.022
protein modification by small protein conjugationGO:0032446790.022
negative regulation of biosynthetic processGO:00098902770.022
connective tissue developmentGO:006144830.022
Mouse
synapse assemblyGO:00074161430.022
peptidyl lysine modificationGO:0018205570.021
negative regulation of cell differentiationGO:00455961430.021
meiotic chromosome condensationGO:001003230.021
posttranscriptional regulation of gene expressionGO:00106081450.021
organic acid metabolic processGO:00060821030.021
regulation of cell morphogenesisGO:00226041630.021
regulation of eye pigmentationGO:004807370.021
response to endogenous stimulusGO:00097191190.021
Mouse
columnar cuboidal epithelial cell differentiationGO:00020652560.021
anterior posterior axis specification follicular epitheliumGO:003071420.020
positive regulation of phosphate metabolic processGO:00459371390.020
regulation of intracellular signal transductionGO:19025312360.019
pole cell migrationGO:0007280130.019
post embryonic hemopoiesisGO:0035166170.019
dna replicationGO:0006260480.019
meiotic nuclear divisionGO:00071261510.019
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092380.019
regulation of microtubule cytoskeleton organizationGO:0070507410.018
embryonic development via the syncytial blastodermGO:00017001480.018
mapk cascadeGO:00001651070.018
skeletal muscle fiber developmentGO:004874130.018
single organism cell adhesionGO:0098602470.018
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.018
cellular response to external stimulusGO:0071496660.018
eye photoreceptor cell fate commitmentGO:0042706370.018
organonitrogen compound metabolic processGO:19015643180.018
Mouse
nuclear axial expansionGO:003519130.018
compound eye photoreceptor developmentGO:0042051780.018
cell cycle checkpointGO:0000075950.017
negative regulation of phosphorus metabolic processGO:0010563450.017
rhythmic processGO:00485111060.017
regulation of mapk cascadeGO:0043408920.017
eggshell formationGO:00307031050.017
autophagyGO:00069141080.017
organ formationGO:0048645390.017
cellular response to hormone stimulusGO:0032870440.017
catabolic processGO:00090564090.017
Mouse
positive regulation of histone deacetylationGO:003106520.016
anterior posterior axis specification embryoGO:00085951030.016
positive regulation of cell migrationGO:003033520.016
regulation of response to stressGO:00801342000.016
regulation of photoreceptor cell differentiationGO:0046532340.016
signal transduction by phosphorylationGO:00230141070.016
lipid metabolic processGO:00066291210.016
Mouse
chromatin assemblyGO:0031497480.016
instar larval developmentGO:0002168550.016
positive regulation of phosphorus metabolic processGO:00105621390.016
positive regulation of protein transportGO:0051222370.015
canonical wnt signaling pathway involved in heart developmentGO:006131630.015
negative regulation of kinase activityGO:0033673160.015
wnt signaling pathwayGO:0016055980.015
Human
regulation of insulin like growth factor receptor signaling pathwayGO:004356730.015
negative regulation of phosphorylationGO:0042326350.015
muscle tissue developmentGO:0060537300.015
apoptotic processGO:00069151590.015
negative regulation of intracellular signal transductionGO:1902532570.015
positive regulation of intracellular transportGO:0032388420.015
germarium derived female germ line cyst formationGO:0030727420.015
regulation of chromatin bindingGO:003556130.015
respiratory system developmentGO:00605412130.015
genitalia developmentGO:0048806260.015
protein targetingGO:0006605640.014
neurological system processGO:00508773580.014
Human
regulation of cell substrate adhesionGO:001081020.014
positive regulation of intracellular signal transductionGO:19025331160.014
equator specificationGO:004531740.014
negative regulation of protein modification processGO:0031400290.014
eye antennal disc morphogenesisGO:0007455340.014
embryonic foregut morphogenesisGO:004861730.014
regulation of protein localization to nucleusGO:1900180290.014
protein targeting to nucleusGO:0044744510.014
positive regulation of molecular functionGO:00440931360.014
regulation of behaviorGO:0050795750.014
establishment of organelle localizationGO:00516561220.014
oocyte differentiationGO:00099941450.013
secretion by cellGO:00329401010.013
cellular response to extracellular stimulusGO:0031668640.013
regulation of glial cell proliferationGO:0060251110.013
single organismal cell cell adhesionGO:0016337450.013
regulation of dna templated transcription in response to stressGO:004362040.013
regulation of striated muscle contractionGO:000694220.013
positive regulation of cell differentiationGO:0045597640.013
gene silencing by rnaGO:0031047570.013
regulation of neuron differentiationGO:00456641030.013
regulation of mitotic cell cycle phase transitionGO:19019901300.013
stress activated mapk cascadeGO:0051403520.013
response to fungusGO:0009620500.013
nurse cell nucleus anchoringGO:000730210.013
cellular component assembly involved in morphogenesisGO:00109271510.012
response to hypoxiaGO:0001666530.012
prostanoid biosynthetic processGO:004645710.012
regulation of proteolysisGO:0030162870.012
organic substance catabolic processGO:19015753080.012
Mouse
negative regulation of cell cycle phase transitionGO:19019881030.012
cytoskeleton dependent cytokinesisGO:0061640810.012
mating behaviorGO:00076171060.012
mitochondrial membrane organizationGO:000700630.012
regulation of hydrolase activityGO:0051336970.012
protein complex biogenesisGO:00702712010.012
positive regulation of protein localization to nucleusGO:1900182210.012
protein processingGO:0016485680.012
histone h4 k16 acetylationGO:004398440.012
axis specificationGO:00097981670.012
spindle localizationGO:0051653220.012
regulation of adult chitin containing cuticle pigmentationGO:0048082130.012
dna damage checkpointGO:0000077780.012
transforming growth factor beta receptor signaling pathwayGO:0007179160.012
nucleoside catabolic processGO:00091641120.012
peripheral nervous system developmentGO:0007422520.012
positive regulation of cell substrate adhesionGO:001081110.012
posttranscriptional gene silencingGO:0016441460.012
positive regulation of kinase activityGO:0033674250.012
formation of a compartment boundaryGO:006028840.012
positive regulation of histone h3 k4 methylationGO:005157110.012
establishment of cell polarityGO:0030010400.012
endodermal cell fate commitmentGO:000171130.012
regulation of phosphatase activityGO:001092130.012
heterocycle catabolic processGO:00467001660.012
p granule organizationGO:003071940.012
neuron fate commitmentGO:0048663500.011
oocyte morphogenesisGO:004860130.011
negative regulation of nucleotide catabolic processGO:003081210.011
regulation of stress activated protein kinase signaling cascadeGO:0070302420.011
morphogenesis of a polarized epitheliumGO:0001738930.011
regulation of cell shapeGO:00083601130.011
chemosensory behaviorGO:00076351060.011
nucleobase containing compound catabolic processGO:00346551650.011
notum morphogenesisGO:004880240.011
regulation of transferase activityGO:0051338580.011
defense responseGO:00069523000.011
oocyte constructionGO:00073081120.011
rna 3 end processingGO:0031123450.011
formation of anatomical boundaryGO:0048859370.011
positive regulation of g2 m transition of mitotic cell cycleGO:001097120.011
organic cyclic compound catabolic processGO:19013611680.011
negative regulation of epidermal growth factor receptor signaling pathwayGO:0042059290.011
mitotic dna damage checkpointGO:0044773740.010
regulation of cell developmentGO:00602842150.010
negative regulation of neurogenesisGO:0050768530.010
regulation of protein import into nucleusGO:0042306280.010
covalent chromatin modificationGO:00165691060.010
male sex differentiationGO:0046661250.010
molting cycle chitin based cuticleGO:0007591560.010
humoral immune responseGO:00069591170.010

ebi disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.044
cancerDOID:16200.025
disease of cellular proliferationDOID:1456600.025
organ system cancerDOID:005068600.016
large intestine cancerDOID:567200.011
gastrointestinal system cancerDOID:311900.011
intestinal cancerDOID:1015500.011
musculoskeletal system diseaseDOID:1700.010
colorectal cancerDOID:925600.010