IMP: Integrative Multi-species Prediction

Drosophila melanogaster

49 known processes

lqfR (Dmel_CG42250)

liquid facets-Related

(Aliases: l(3)dsl-9,Epsin,epsin-like,CG31285,Dmel_CG31285,l(3)03685,CG31170,l(3)SG62,l(3)XII-10,epsin,XII-10,Dmel\CG42250,l(3)A9,l(3)dsl9,CG42250,CG13853,epsin02,LqfR,CG13854,Dmel_CG31170)

FLYBASE: FBgn0261279
Entrez: 42632
UniProtKB: Q9VD13
UniProtKB: Q8IN05

Process Predictions
Disease Predictions

lqfR biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
notch signaling pathway	GO:0007219	120	0.766
eggshell chorion gene amplification	GO:0007307	9	0.598
eye photoreceptor cell differentiation	GO:0001754	145	0.538
compound eye photoreceptor fate commitment	GO:0001752	36	0.459
protein transport	GO:0015031	155	0.382
photoreceptor cell differentiation	GO:0046530	170	0.358
establishment of protein localization	GO:0045184	163	0.354
single organism membrane organization	GO:0044802	93	0.335
intracellular transport	GO:0046907	228	0.326
aging	GO:0007568	143	0.317
cellular catabolic process	GO:0044248	372	0.291
negative regulation of organ growth	GO:0046621	15	0.290
regulation of organelle organization	GO:0033043	196	0.288
aromatic compound catabolic process	GO:0019439	166	0.285
regionalization	GO:0003002	416	0.276
protein localization	GO:0008104	284	0.269
embryo development ending in birth or egg hatching	GO:0009792	152	0.263
compound eye development	GO:0048749	307	0.248
rhabdomere development	GO:0042052	38	0.244
catabolic process	GO:0009056	409	0.205
epidermal cell differentiation	GO:0009913	51	0.205
compound eye photoreceptor cell differentiation	GO:0001751	140	0.203
golgi to plasma membrane protein transport	GO:0043001	8	0.203
actin filament organization	GO:0007015	126	0.202
macromolecule catabolic process	GO:0009057	161	0.197
establishment of localization in cell	GO:0051649	402	0.196
membrane organization	GO:0061024	112	0.194
negative regulation of mitotic cell cycle	GO:0045930	109	0.190
cytoplasmic transport	GO:0016482	130	0.182
hippo signaling	GO:0035329	20	0.171
negative regulation of multicellular organismal process	GO:0051241	142	0.168
organic substance catabolic process	GO:1901575	308	0.158
cellular macromolecule catabolic process	GO:0044265	136	0.152
germarium derived oocyte fate determination	GO:0007294	26	0.152
posttranscriptional gene silencing	GO:0016441	46	0.148
sensory organ morphogenesis	GO:0090596	260	0.141
regulation of cellular catabolic process	GO:0031329	157	0.140
compound eye morphogenesis	GO:0001745	249	0.138
actin filament based process	GO:0030029	220	0.133
vesicle mediated transport	GO:0016192	381	0.128
gene silencing by rna	GO:0031047	57	0.128
intracellular protein transport	GO:0006886	104	0.125
regulation of multicellular organismal development	GO:2000026	414	0.120
body morphogenesis	GO:0010171	2	0.118
regulation of localization	GO:0032879	275	0.114
ovarian follicle cell development	GO:0030707	248	0.111
compound eye photoreceptor development	GO:0042051	78	0.108
cell cycle phase transition	GO:0044770	140	0.107
modification dependent protein catabolic process	GO:0019941	78	0.103
plasma membrane organization	GO:0007009	26	0.095
epithelial cell differentiation	GO:0030855	322	0.093
morphogenesis of a polarized epithelium	GO:0001738	93	0.092
actin polymerization or depolymerization	GO:0008154	31	0.092
appendage morphogenesis	GO:0035107	397	0.091
embryonic morphogenesis	GO:0048598	206	0.090
organonitrogen compound catabolic process	GO:1901565	128	0.090
larval midgut histolysis	GO:0035069	22	0.090
actin filament polymerization	GO:0030041	27	0.089
cellular component assembly involved in morphogenesis	GO:0010927	151	0.089
establishment of protein localization to membrane	GO:0090150	11	0.089
response to biotic stimulus	GO:0009607	294	0.084
eye morphogenesis	GO:0048592	260	0.084
regulation of transport	GO:0051049	181	0.083
negative regulation of signal transduction	GO:0009968	206	0.082
eye development	GO:0001654	323	0.080
regulation of catabolic process	GO:0009894	170	0.080
regulation of lamellipodium organization	GO:1902743	15	0.079
dna amplification	GO:0006277	11	0.077
positive regulation of signaling	GO:0023056	243	0.075
establishment of planar polarity	GO:0001736	87	0.075
eggshell chorion assembly	GO:0007306	66	0.075
regulation of cellular component size	GO:0032535	98	0.074
positive regulation of catabolic process	GO:0009896	105	0.070
muscle cell differentiation	GO:0042692	103	0.069
mitotic nuclear division	GO:0007067	213	0.069
regulation of establishment of protein localization	GO:0070201	61	0.068
heterocycle catabolic process	GO:0046700	166	0.068
posttranscriptional regulation of gene expression	GO:0010608	145	0.065
modification dependent macromolecule catabolic process	GO:0043632	79	0.065
single organism intracellular transport	GO:1902582	207	0.064
mitotic cell cycle phase transition	GO:0044772	138	0.064
positive regulation of signal transduction	GO:0009967	223	0.063
membrane biogenesis	GO:0044091	8	0.062
regulation of cell cycle	GO:0051726	291	0.062
oocyte differentiation	GO:0009994	145	0.060
columnar cuboidal epithelial cell development	GO:0002066	249	0.059
organ growth	GO:0035265	56	0.058
appendage development	GO:0048736	401	0.057
photoreceptor cell development	GO:0042461	96	0.057
cell death	GO:0008219	279	0.056
larval development	GO:0002164	104	0.055
post golgi vesicle mediated transport	GO:0006892	11	0.055
ribonucleoside catabolic process	GO:0042454	112	0.054
skin development	GO:0043588	65	0.054
germarium derived egg chamber formation	GO:0007293	101	0.054
epithelial cell development	GO:0002064	274	0.053
growth	GO:0040007	359	0.053
regulation of cell development	GO:0060284	215	0.053
striated muscle cell differentiation	GO:0051146	90	0.052
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.051
regulation of actin cytoskeleton organization	GO:0032956	42	0.050
intracellular mrna localization involved in pattern specification process	GO:0060810	56	0.049
cell migration	GO:0016477	238	0.049
regulation of cellular localization	GO:0060341	136	0.048
nucleus localization	GO:0051647	34	0.048
wing disc morphogenesis	GO:0007472	344	0.047
organonitrogen compound metabolic process	GO:1901564	318	0.046
ras protein signal transduction	GO:0007265	88	0.046
eggshell formation	GO:0030703	105	0.045
regulation of intracellular protein transport	GO:0033157	46	0.045
negative regulation of signaling	GO:0023057	219	0.044
oocyte development	GO:0048599	124	0.044
single organism catabolic process	GO:0044712	228	0.043
proteolysis	GO:0006508	192	0.043
glycosyl compound metabolic process	GO:1901657	127	0.043
torc1 signaling	GO:0038202	12	0.043
sex differentiation	GO:0007548	81	0.043
oocyte construction	GO:0007308	112	0.043
adherens junction organization	GO:0034332	27	0.043
salivary gland development	GO:0007431	162	0.043
cellular protein complex assembly	GO:0043623	71	0.043
regulation of cell growth	GO:0001558	43	0.042
negative regulation of response to stimulus	GO:0048585	258	0.042
intracellular signal transduction	GO:0035556	300	0.041
nucleoside phosphate catabolic process	GO:1901292	110	0.041
cell growth	GO:0016049	108	0.040
positive regulation of macromolecule metabolic process	GO:0010604	405	0.040
regulation of cell substrate adhesion	GO:0010810	2	0.039
positive regulation of cellular catabolic process	GO:0031331	95	0.039
proteolysis involved in cellular protein catabolic process	GO:0051603	83	0.039
nucleotide metabolic process	GO:0009117	161	0.038
lamellipodium assembly	GO:0030032	21	0.038
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	54	0.038
regulation of cell morphogenesis	GO:0022604	163	0.037
purine ribonucleoside metabolic process	GO:0046128	127	0.037
dorsal ventral axis specification ovarian follicular epithelium	GO:0008069	13	0.037
negative regulation of actin filament polymerization	GO:0030837	7	0.037
regulation of protein transport	GO:0051223	57	0.036
post embryonic appendage morphogenesis	GO:0035120	385	0.035
determination of adult lifespan	GO:0008340	137	0.035
muscle structure development	GO:0061061	224	0.035
positive regulation of phosphorylation	GO:0042327	87	0.035
negative regulation of cell communication	GO:0010648	223	0.035
regulation of cell projection assembly	GO:0060491	30	0.034
golgi vesicle transport	GO:0048193	27	0.034
regulation of intracellular signal transduction	GO:1902531	236	0.034
guanosine containing compound metabolic process	GO:1901068	74	0.034
regulation of notch signaling pathway	GO:0008593	100	0.033
phosphorylation	GO:0016310	294	0.033
positive regulation of phosphorus metabolic process	GO:0010562	139	0.033
positive regulation of response to stimulus	GO:0048584	323	0.033
developmental programmed cell death	GO:0010623	138	0.032
cellular nitrogen compound catabolic process	GO:0044270	165	0.032
germarium derived oocyte differentiation	GO:0030706	29	0.032
regulation of ras protein signal transduction	GO:0046578	93	0.032
cytokinesis	GO:0000910	90	0.032
purine nucleoside metabolic process	GO:0042278	127	0.032
pole plasm rna localization	GO:0007316	52	0.031
regulation of intracellular transport	GO:0032386	64	0.031
nucleoside metabolic process	GO:0009116	127	0.031
purine nucleotide metabolic process	GO:0006163	146	0.031
positive regulation of autophagy	GO:0010508	21	0.030
regulation of anatomical structure size	GO:0090066	163	0.030
chorion containing eggshell formation	GO:0007304	105	0.030
regulation of protein localization	GO:0032880	76	0.030
regulation of phosphorus metabolic process	GO:0051174	210	0.030
mitotic g2 m transition checkpoint	GO:0044818	70	0.030
phagocytosis	GO:0006909	215	0.030
segmentation	GO:0035282	207	0.030
macromolecular complex assembly	GO:0065003	256	0.029
germ line cyst formation	GO:0048134	44	0.029
r8 cell fate specification	GO:0045464	5	0.029
regulation of actin filament polymerization	GO:0030833	25	0.029
protein secretion	GO:0009306	45	0.029
regulation of nuclear division	GO:0051783	58	0.029
death	GO:0016265	284	0.029
chromosome segregation	GO:0007059	157	0.028
induction of programmed cell death by hormones	GO:0035081	12	0.028
blastoderm segmentation	GO:0007350	159	0.028
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.028
regulation of cell cycle process	GO:0010564	181	0.028
regulation of epithelial cell differentiation	GO:0030856	4	0.028
salivary gland cell autophagic cell death	GO:0035071	83	0.027
negative regulation of growth	GO:0045926	84	0.027
cellular macromolecule localization	GO:0070727	220	0.027
mitotic sister chromatid segregation	GO:0000070	87	0.026
cytoplasm organization	GO:0007028	64	0.026
proteasomal protein catabolic process	GO:0010498	59	0.025
cellular protein localization	GO:0034613	160	0.025
mapk cascade	GO:0000165	107	0.025
regulation of mitosis	GO:0007088	56	0.025
protein localization to plasma membrane	GO:0072659	13	0.025
defense response to bacterium	GO:0042742	178	0.025
positive regulation of developmental process	GO:0051094	143	0.024
nucleoside triphosphate catabolic process	GO:0009143	108	0.024
nucleoside phosphate metabolic process	GO:0006753	162	0.024
protein complex assembly	GO:0006461	200	0.024
regulation of cytoskeleton organization	GO:0051493	89	0.023
regulation of cell cycle phase transition	GO:1901987	130	0.023
endosomal transport	GO:0016197	44	0.023
establishment or maintenance of apical basal cell polarity	GO:0035088	34	0.023
eye photoreceptor cell development	GO:0042462	81	0.023
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.023
regulation of cell proliferation	GO:0042127	163	0.023
positive regulation of rna metabolic process	GO:0051254	271	0.023
ribonucleotide catabolic process	GO:0009261	109	0.023
establishment of tissue polarity	GO:0007164	87	0.023
tissue death	GO:0016271	102	0.023
regulation of sister chromatid cohesion	GO:0007063	2	0.023
cellular protein catabolic process	GO:0044257	83	0.022
multicellular organismal aging	GO:0010259	140	0.022
establishment of nucleus localization	GO:0040023	26	0.022
lipid modification	GO:0030258	24	0.022
secretion by cell	GO:0032940	101	0.022
purine ribonucleoside catabolic process	GO:0046130	112	0.022
regulation of cell adhesion	GO:0030155	27	0.022
positive regulation of cell communication	GO:0010647	250	0.022
metaphase anaphase transition of cell cycle	GO:0044784	28	0.021
defense response to other organism	GO:0098542	225	0.021
lateral inhibition	GO:0046331	206	0.021
regulation of vesicle mediated transport	GO:0060627	59	0.021
response to organic cyclic compound	GO:0014070	89	0.021
cellular response to decreased oxygen levels	GO:0036294	30	0.020
regulation of actin filament length	GO:0030832	27	0.020
purine ribonucleotide metabolic process	GO:0009150	145	0.020
endomembrane system organization	GO:0010256	119	0.020
purine nucleoside catabolic process	GO:0006152	112	0.020
macroautophagy	GO:0016236	42	0.020
ribose phosphate metabolic process	GO:0019693	145	0.020
pole plasm assembly	GO:0007315	61	0.020
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.019
organic cyclic compound catabolic process	GO:1901361	168	0.019
rna processing	GO:0006396	147	0.019
purine containing compound catabolic process	GO:0072523	112	0.019
posttranscriptional gene silencing by rna	GO:0035194	45	0.019
golgi to plasma membrane transport	GO:0006893	8	0.019
endocytosis	GO:0006897	310	0.019
peptidyl threonine modification	GO:0018210	3	0.019
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.019
negative regulation of organelle organization	GO:0010639	56	0.018
regulation of phosphate metabolic process	GO:0019220	210	0.018
establishment or maintenance of microtubule cytoskeleton polarity	GO:0030951	41	0.018
chaeta development	GO:0022416	97	0.018
positive regulation of mapk cascade	GO:0043410	63	0.018
cellular response to nutrient levels	GO:0031669	62	0.018
tube morphogenesis	GO:0035239	191	0.018
nuclear transcribed mrna catabolic process	GO:0000956	24	0.018
regulation of actin polymerization or depolymerization	GO:0008064	27	0.018
signal transduction by phosphorylation	GO:0023014	107	0.018
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.018
rho protein signal transduction	GO:0007266	14	0.018
establishment or maintenance of polarity of follicular epithelium	GO:0016334	26	0.017
negative regulation of cellular metabolic process	GO:0031324	382	0.017
protein complex biogenesis	GO:0070271	201	0.017
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.017
apoptotic process	GO:0006915	159	0.017
biological adhesion	GO:0022610	138	0.017
regulation of mitotic cell cycle	GO:0007346	190	0.017
nucleobase containing small molecule metabolic process	GO:0055086	174	0.017
regulation of epidermal cell differentiation	GO:0045604	3	0.017
tissue morphogenesis	GO:0048729	297	0.017
wound healing	GO:0042060	75	0.017
protein catabolic process	GO:0030163	101	0.017
mrna metabolic process	GO:0016071	124	0.016
nucleoside catabolic process	GO:0009164	112	0.016
negative regulation of developmental process	GO:0051093	201	0.016
mitotic dna damage checkpoint	GO:0044773	74	0.016
salivary gland morphogenesis	GO:0007435	145	0.016
ubiquitin dependent protein catabolic process	GO:0006511	78	0.016
positive regulation of hydrolase activity	GO:0051345	78	0.016
epidermis development	GO:0008544	65	0.016
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.016
reproductive system development	GO:0061458	74	0.016
negative regulation of cell cycle phase transition	GO:1901988	103	0.016
cuticle pattern formation	GO:0035017	27	0.015
response to wounding	GO:0009611	94	0.015
positive regulation of mitotic sister chromatid separation	GO:1901970	10	0.015
organic substance transport	GO:0071702	257	0.015
cellular response to chemical stimulus	GO:0070887	199	0.015
purine ribonucleotide catabolic process	GO:0009154	109	0.015
rna 3 end processing	GO:0031123	45	0.015
small gtpase mediated signal transduction	GO:0007264	88	0.015
mitotic cell cycle checkpoint	GO:0007093	88	0.015
regulation of translation	GO:0006417	56	0.014
actin filament bundle organization	GO:0061572	28	0.014
positive regulation of intracellular protein transport	GO:0090316	30	0.014
reproductive structure development	GO:0048608	74	0.014
embryonic pattern specification	GO:0009880	174	0.014
protein complex disassembly	GO:0043241	36	0.014
contractile actin filament bundle assembly	GO:0030038	1	0.014
organophosphate metabolic process	GO:0019637	195	0.014
autophagic cell death	GO:0048102	83	0.014
autophagic vacuole assembly	GO:0000045	2	0.014
cellular macromolecular complex assembly	GO:0034622	153	0.014
gtp metabolic process	GO:0046039	72	0.014
spermatid development	GO:0007286	98	0.014
cellular response to peptide	GO:1901653	28	0.014
regulation of molecular function	GO:0065009	217	0.014
central nervous system development	GO:0007417	201	0.013
actin cytoskeleton organization	GO:0030036	206	0.013
regulation of mapk cascade	GO:0043408	92	0.013
organophosphate catabolic process	GO:0046434	112	0.013
dorsal ventral pattern formation imaginal disc	GO:0007450	51	0.013
carbohydrate derivative metabolic process	GO:1901135	217	0.013
negative regulation of cellular component organization	GO:0051129	108	0.013
organelle fission	GO:0048285	340	0.013
monocarboxylic acid catabolic process	GO:0072329	10	0.013
negative regulation of developmental growth	GO:0048640	64	0.013
nucleobase containing compound catabolic process	GO:0034655	165	0.013
sister chromatid cohesion	GO:0007062	18	0.013
neuron fate commitment	GO:0048663	50	0.013
regulation of nucleotide catabolic process	GO:0030811	48	0.013
positive regulation of biosynthetic process	GO:0009891	316	0.013
regulation of mrna metabolic process	GO:1903311	72	0.013
exocrine system development	GO:0035272	162	0.013
regulation of mrna catabolic process	GO:0061013	5	0.012
cell junction organization	GO:0034330	57	0.012
regulation of secretion	GO:0051046	44	0.012
response to hypoxia	GO:0001666	53	0.012
extrinsic apoptotic signaling pathway	GO:0097191	1	0.012
axis specification	GO:0009798	167	0.012
cell cycle g1 s phase transition	GO:0044843	31	0.012
actin filament capping	GO:0051693	2	0.012
gland morphogenesis	GO:0022612	145	0.012
protein dephosphorylation	GO:0006470	27	0.012
cell motility	GO:0048870	251	0.012
appendage segmentation	GO:0035285	26	0.012
wnt signaling pathway	GO:0016055	98	0.012
regulation of actin filament based process	GO:0032970	42	0.012
negative regulation of cell proliferation	GO:0008285	69	0.012
development of primary sexual characteristics	GO:0045137	50	0.012
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.012
ribonucleotide metabolic process	GO:0009259	145	0.012
zonula adherens assembly	GO:0045186	6	0.012
nucleoside triphosphate metabolic process	GO:0009141	120	0.012
striated muscle cell development	GO:0055002	50	0.012
negative regulation of neurogenesis	GO:0050768	53	0.012
rna catabolic process	GO:0006401	37	0.012
positive regulation of ras protein signal transduction	GO:0046579	43	0.012
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.011
response to decreased oxygen levels	GO:0036293	58	0.011
regulation of cellular protein metabolic process	GO:0032268	243	0.011
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.011
adherens junction assembly	GO:0034333	11	0.011
regulation of jnk cascade	GO:0046328	40	0.011
regulation of epidermis development	GO:0045682	3	0.011
positive regulation of molecular function	GO:0044093	136	0.011
regulation of phosphorylation	GO:0042325	147	0.011
nucleocytoplasmic transport	GO:0006913	72	0.011
oocyte anterior posterior axis specification	GO:0007314	72	0.011
regulation of purine nucleotide metabolic process	GO:1900542	62	0.011
regulation of lipid kinase activity	GO:0043550	2	0.011
regulation of protein complex disassembly	GO:0043244	29	0.011
nucleotide catabolic process	GO:0009166	109	0.011
response to external biotic stimulus	GO:0043207	293	0.011
regulation of mitotic sister chromatid segregation	GO:0033047	28	0.011
imaginal disc derived wing morphogenesis	GO:0007476	337	0.011
regulation of cytoplasmic transport	GO:1903649	47	0.011
regulation of cell fate commitment	GO:0010453	29	0.011
gtp catabolic process	GO:0006184	72	0.011
stress activated protein kinase signaling cascade	GO:0031098	55	0.011
positive regulation of growth	GO:0045927	75	0.011
salivary gland histolysis	GO:0035070	88	0.011
purine nucleotide catabolic process	GO:0006195	109	0.011
regulation of axon regeneration	GO:0048679	4	0.011
protein polymerization	GO:0051258	42	0.010
oocyte microtubule cytoskeleton polarization	GO:0008103	22	0.010
rna interference	GO:0016246	27	0.010
equator specification	GO:0045317	4	0.010
protein targeting	GO:0006605	64	0.010
activation of rho gtpase activity	GO:0032862	3	0.010
positive regulation of small gtpase mediated signal transduction	GO:0051057	43	0.010
pupal development	GO:0035209	11	0.010
induction of programmed cell death by ecdysone	GO:0035078	12	0.010
regulation of proteolysis	GO:0030162	87	0.010
macromolecular complex disassembly	GO:0032984	37	0.010
pre mirna processing	GO:0031054	3	0.010
genitalia development	GO:0048806	26	0.010
establishment or maintenance of cytoskeleton polarity	GO:0030952	44	0.010

lqfR disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of cellular proliferation	DOID:14566	0.024
organ system cancer	DOID:0050686	0.019
cancer	DOID:162	0.019

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