Drosophila melanogaster

0 known processes

rab3-GEF (Dmel_CG5627)

CG5627 gene product from transcript CG5627-RB

(Aliases: CG5627,Dmel\CG5627,anon-EST:Posey246,BEST:GH21304)

rab3-GEF biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
g protein coupled receptor signaling pathwayGO:00071861360.064
small molecule metabolic processGO:00442813050.038
response to other organismGO:00517072930.037
vesicle mediated transportGO:00161923810.036
response to external biotic stimulusGO:00432072930.036
salt aversionGO:003519930.036
response to organic substanceGO:00100332840.036
eye developmentGO:00016543230.036
post embryonic appendage morphogenesisGO:00351203850.035
cellular protein modification processGO:00064644380.034
neurological system processGO:00508773580.034
single organism biosynthetic processGO:00447112060.034
organelle fissionGO:00482853400.033
regulation of localizationGO:00328792750.033
single organism behaviorGO:00447083910.032
appendage morphogenesisGO:00351073970.032
imaginal disc derived wing morphogenesisGO:00074763370.032
protein modification processGO:00362114380.032
organonitrogen compound metabolic processGO:19015643180.031
negative regulation of cellular metabolic processGO:00313243820.031
immune system processGO:00023763470.030
appendage developmentGO:00487364010.030
organic substance catabolic processGO:19015753080.030
transmembrane transportGO:00550851390.030
imaginal disc derived appendage developmentGO:00487373990.030
cell cell signaling involved in cell fate commitmentGO:00451682100.030
catabolic processGO:00090564090.030
nuclear divisionGO:00002803320.030
response to biotic stimulusGO:00096072940.030
lateral inhibitionGO:00463312060.029
defense responseGO:00069523000.029
organic substance transportGO:00717022570.029
imaginal disc derived appendage morphogenesisGO:00351143950.029
chemotaxisGO:00069352490.028
transcription from rna polymerase ii promoterGO:00063663680.028
body morphogenesisGO:001017120.028
ion transmembrane transportGO:00342201220.028
epithelial cell differentiationGO:00308553220.028
regulation of transcription from rna polymerase ii promoterGO:00063573780.028
cellular response to chemical stimulusGO:00708871990.027
response to bacteriumGO:00096171980.027
taxisGO:00423303040.026
phagocytosisGO:00069092150.026
positive regulation of macromolecule metabolic processGO:00106044050.026
response to abiotic stimulusGO:00096283410.026
camera type eye developmentGO:004301040.026
negative regulation of biosynthetic processGO:00098902770.026
response to lipopolysaccharideGO:003249640.026
chromosome organizationGO:00512763600.026
endocytosisGO:00068973100.026
negative regulation of cellular biosynthetic processGO:00313272770.026
establishment of localization in cellGO:00516494020.025
negative regulation of nitrogen compound metabolic processGO:00511722650.025
compound eye developmentGO:00487493070.025
axon guidanceGO:00074112330.024
homeostatic processGO:00425921990.024
wing disc morphogenesisGO:00074723440.024
oxoacid metabolic processGO:00434361030.024
adult behaviorGO:00305341370.024
positive regulation of response to stimulusGO:00485843230.024
phosphorylationGO:00163102940.023
neuron recognitionGO:00080381010.023
regulation of transportGO:00510491810.023
cell recognitionGO:00080371020.022
regulation of multicellular organismal developmentGO:20000264140.022
negative regulation of gene expressionGO:00106293870.022
organic acid metabolic processGO:00060821030.022
ion transportGO:00068111450.022
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.022
organophosphate metabolic processGO:00196371950.022
axonogenesisGO:00074092900.021
negative regulation of response to stimulusGO:00485852580.021
inorganic ion transmembrane transportGO:0098660730.021
sterol homeostasisGO:005509240.021
meiotic nuclear divisionGO:00071261510.021
cellular amino acid metabolic processGO:0006520610.021
regionalizationGO:00030024160.021
macromolecular complex assemblyGO:00650032560.021
sensory perceptionGO:00076001960.020
regulation of molecular functionGO:00650092170.020
nucleobase containing small molecule metabolic processGO:00550861740.020
intracellular signal transductionGO:00355563000.020
negative regulation of macromolecule biosynthetic processGO:00105582700.020
cellular catabolic processGO:00442483720.020
eye morphogenesisGO:00485922600.020
regulation of cell cycleGO:00517262910.020
sensory perception of salty tasteGO:005091430.020
synapse organizationGO:00508081960.020
behavioral response to ethanolGO:0048149490.020
positive regulation of signalingGO:00230562430.020
localization of cellGO:00516742570.020
hormone catabolic processGO:004244730.020
synaptic transmissionGO:00072682880.020
carbohydrate derivative metabolic processGO:19011352170.019
positive regulation of cell communicationGO:00106472500.019
response to oxygen containing compoundGO:19017002000.019
salivary gland morphogenesisGO:00074351450.019
defense response to bacteriumGO:00427421780.019
regulation of cellular amine metabolic processGO:003323830.019
defense response to other organismGO:00985422250.019
negative regulation of cell communicationGO:00106482230.019
chromatin modificationGO:00165681470.019
positive regulation of nitrogen compound metabolic processGO:00511733540.019
columnar cuboidal epithelial cell developmentGO:00020662490.019
cation transportGO:00068121100.019
response to radiationGO:00093141550.019
olfactory behaviorGO:0042048970.019
immune responseGO:00069552460.019
response to light stimulusGO:00094161240.019
carboxylic acid metabolic processGO:0019752920.018
cellular ketone metabolic processGO:0042180240.018
locomotory behaviorGO:00076261760.018
regulation of cellular amino acid metabolic processGO:000652100.018
amine metabolic processGO:0009308120.018
lipid metabolic processGO:00066291210.018
developmental maturationGO:00217001720.018
negative regulation of rna metabolic processGO:00512532510.018
regulation of cellular ketone metabolic processGO:001056530.018
regulation of cell differentiationGO:00455953020.018
cellular response to organic substanceGO:00713101320.018
forebrain developmentGO:003090020.018
single organism catabolic processGO:00447122280.018
matingGO:00076181200.018
response to organophosphorusGO:004668320.018
positive regulation of cell migrationGO:003033520.018
protein localizationGO:00081042840.018
regulation of protein metabolic processGO:00512462560.018
neuron projection guidanceGO:00974852410.018
developmental growthGO:00485892800.017
negative regulation of nucleobase containing compound metabolic processGO:00459342610.017
nucleoside phosphate metabolic processGO:00067531620.017
kidney developmentGO:000182230.017
regulation of response to stressGO:00801342000.017
positive regulation of nucleobase containing compound metabolic processGO:00459353320.017
axon developmentGO:00615642970.017
immune response activating signal transductionGO:000275720.017
sensory organ morphogenesisGO:00905962600.017
purine containing compound metabolic processGO:00725211550.017
positive regulation of signal transductionGO:00099672230.017
neuropeptide signaling pathwayGO:0007218450.017
ameboidal type cell migrationGO:00016671510.017
compound eye morphogenesisGO:00017452490.017
epithelial cell developmentGO:00020642740.017
actin filament based processGO:00300292200.017
chromatin organizationGO:00063252070.017
regulation of nervous system developmentGO:00519602480.017
positive regulation of cell motilityGO:200014730.017
regulation of anatomical structure sizeGO:00900661630.017
sensory perception of chemical stimulusGO:00076061160.016
regulation of epithelial cell proliferationGO:005067840.016
cellular macromolecule localizationGO:00707272200.016
detection of stimulusGO:00516061560.016
immune response regulating signaling pathwayGO:000276420.016
regulation of immune system processGO:00026821760.016
negative regulation of developmental processGO:00510932010.016
regulation of cellular component biogenesisGO:00440872010.016
chromosome segregationGO:00070591570.016
regulation of cellular protein metabolic processGO:00322682430.016
actin filament organizationGO:00070151260.016
regulation of organelle organizationGO:00330431960.016
negative regulation of nucleic acid templated transcriptionGO:19035072400.016
intracellular transportGO:00469072280.016
regulation of multi organism processGO:00439001310.016
meiotic cell cycleGO:00513211710.016
spindle organizationGO:00070512530.016
mitotic nuclear divisionGO:00070672130.016
single organism intracellular transportGO:19025822070.016
cell migrationGO:00164772380.016
positive regulation of macromolecule biosynthetic processGO:00105572830.016
columnar cuboidal epithelial cell differentiationGO:00020652560.016
cell deathGO:00082192790.016
polyol biosynthetic processGO:004617330.016
regulation of phosphorus metabolic processGO:00511742100.016
growthGO:00400073590.016
meiotic cell cycle processGO:19030461320.016
negative regulation of signalingGO:00230572190.016
positive regulation of cellular biosynthetic processGO:00313283160.016
regulation of anatomical structure morphogenesisGO:00226032420.016
carbohydrate derivative biosynthetic processGO:1901137850.016
nucleobase containing compound catabolic processGO:00346551650.016
proteolysisGO:00065081920.016
segmentationGO:00352822070.016
embryonic pattern specificationGO:00098801740.016
developmental programmed cell deathGO:00106231380.015
cell proliferationGO:00082832990.015
rna processingGO:00063961470.015
macromolecule catabolic processGO:00090571610.015
multi multicellular organism processGO:00447061230.015
chemosensory behaviorGO:00076351060.015
chromatin remodelingGO:0006338720.015
cholesterol homeostasisGO:004263230.015
connective tissue developmentGO:006144830.015
organonitrogen compound biosynthetic processGO:19015661170.015
salivary gland developmentGO:00074311620.015
regulation of cellular catabolic processGO:00313291570.015
morphogenesis of an epitheliumGO:00020092760.015
cell divisionGO:00513012480.015
chemical homeostasisGO:0048878920.015
positive regulation of rna biosynthetic processGO:19026802660.015
exocrine system developmentGO:00352721620.015
deathGO:00162652840.015
positive regulation of biosynthetic processGO:00098913160.015
cellular nitrogen compound catabolic processGO:00442701650.015
response to alcoholGO:0097305950.015
regulation of developmental growthGO:00486381740.015
establishment of protein localizationGO:00451841630.015
innate immune responseGO:00450871440.015
synaptic target recognitionGO:0008039450.015
regulation of mitotic cell cycleGO:00073461900.015
cytoplasmic transportGO:00164821300.015
response to ethanolGO:0045471590.015
response to monosaccharideGO:003428440.015
regulation of catalytic activityGO:00507901850.015
mitotic cell cycle phase transitionGO:00447721380.015
regulation of immune responseGO:00507761180.014
ovarian follicle cell developmentGO:00307072480.014
protein transportGO:00150311550.014
store operated calcium entryGO:000211530.014
anion homeostasisGO:005508130.014
defense response to gram negative bacteriumGO:0050829940.014
negative regulation of signal transductionGO:00099682060.014
nucleotide metabolic processGO:00091171610.014
tissue migrationGO:00901301550.014
cell adhesionGO:00071551360.014
retina development in camera type eyeGO:006004140.014
ras protein signal transductionGO:0007265880.014
positive regulation of gene expressionGO:00106282900.014
embryonic development via the syncytial blastodermGO:00017001480.014
protein phosphorylationGO:00064681690.014
heterocycle catabolic processGO:00467001660.014
cellular protein localizationGO:00346131600.014
negative regulation of transcription dna templatedGO:00458922370.014
metal ion transportGO:0030001740.014
cellular response to lipopolysaccharideGO:007122230.014
detection of stimulus involved in sensory perceptionGO:0050906920.014
aromatic compound catabolic processGO:00194391660.014
l amino acid importGO:004309220.014
gland morphogenesisGO:00226121450.014
detection of chemical stimulus involved in sensory perceptionGO:0050907750.014
negative regulation of multicellular organismal processGO:00512411420.014
gland developmentGO:00487321910.014
regulation of cell developmentGO:00602842150.014
tripartite regional subdivisionGO:00073511030.014
kidney epithelium developmentGO:007207330.014
ribose phosphate metabolic processGO:00196931450.014
organonitrogen compound catabolic processGO:19015651280.014
cellular amine metabolic processGO:0044106120.014
programmed cell deathGO:00125012570.014
ethanolamine containing compound metabolic processGO:004243940.014
gene silencingGO:00164581380.014
tissue morphogenesisGO:00487292970.014
regulation of cellular localizationGO:00603411360.014
response to hexoseGO:000974630.014
activation of innate immune responseGO:000221840.013
multi organism behaviorGO:00517051750.013
dna packagingGO:0006323910.013
organelle localizationGO:00516401480.013
camera type eye morphogenesisGO:004859320.013
developmental pigmentationGO:0048066680.013
ribonucleotide metabolic processGO:00092591450.013
cell motilityGO:00488702510.013
protein complex biogenesisGO:00702712010.013
dorsal ventral pattern formationGO:00099531330.013
mesenchymal cell differentiationGO:004876210.013
enzyme linked receptor protein signaling pathwayGO:00071671790.013
motor neuron axon guidanceGO:0008045580.013
secretion by cellGO:00329401010.013
axis specificationGO:00097981670.013
response to endogenous stimulusGO:00097191190.013
telencephalon developmentGO:002153720.013
innate immune response activating signal transductionGO:000275820.013
hindbrain developmentGO:003090220.013
negative regulation of cellular component organizationGO:00511291080.013
androgen metabolic processGO:000820910.013
organic cyclic compound catabolic processGO:19013611680.013
single organism cellular localizationGO:19025801800.013
actin cytoskeleton organizationGO:00300362060.013
epithelium migrationGO:00901321480.013
dendrite developmentGO:00163582040.013
regulation of intracellular signal transductionGO:19025312360.013
compound eye photoreceptor developmentGO:0042051780.013
response to glucoseGO:000974920.013
dna metabolic processGO:00062592270.013
limb developmentGO:006017310.013
blastoderm segmentationGO:00073501590.013
positive regulation of rna metabolic processGO:00512542710.013
biological adhesionGO:00226101380.013
humoral immune responseGO:00069591170.013
detection of external stimulusGO:0009581660.012
mitotic spindle organizationGO:00070522200.012
cellular homeostasisGO:0019725800.012
vitamin metabolic processGO:000676620.012
adult locomotory behaviorGO:0008344760.012
nitrogen compound transportGO:0071705850.012
leg disc developmentGO:0035218920.012
protein complex assemblyGO:00064612000.012
positive regulation of nucleic acid templated transcriptionGO:19035082660.012
chaeta developmentGO:0022416970.012
regulation of cell deathGO:00109411730.012
synaptic growth at neuromuscular junctionGO:00511241190.012
signal transduction by phosphorylationGO:00230141070.012
positive regulation of multicellular organismal processGO:00512401430.012
positive regulation of cellular amine metabolic processGO:003324000.012
cation transmembrane transportGO:0098655880.012
autophagic cell deathGO:0048102830.012
cellular response to ethanolGO:007136140.012
regulation of catabolic processGO:00098941700.012
fat soluble vitamin metabolic processGO:000677510.012
endomembrane system organizationGO:00102561190.012
regulation of synaptic transmissionGO:0050804690.012
cellular response to molecule of bacterial originGO:007121930.012
rhythmic processGO:00485111060.012
response to temperature stimulusGO:00092661060.012
vitamin biosynthetic processGO:000911010.012
negative regulation of gene expression epigeneticGO:0045814770.012
mesenchymal cell developmentGO:001403110.012
response to nutrient levelsGO:00316671140.012
dna conformation changeGO:00711031050.012
oocyte axis specificationGO:00073091080.012
response to copper ionGO:004668840.012
compound eye photoreceptor cell differentiationGO:00017511400.012
cellular macromolecule catabolic processGO:00442651360.012
fat soluble vitamin biosynthetic processGO:004236210.012
male gamete generationGO:00482322010.012
sensory perception of smellGO:0007608800.012
anterior posterior axis specification embryoGO:00085951030.012
estrogen metabolic processGO:000821010.012
cellular response to carbohydrate stimulusGO:007132240.012
regulation of cell cycle processGO:00105641810.012
cell maturationGO:00484691440.012
carbohydrate derivative catabolic processGO:19011361180.012
small gtpase mediated signal transductionGO:0007264880.012
purine ribonucleoside catabolic processGO:00461301120.012
glycosyl compound metabolic processGO:19016571270.012
regulation of synapse structure and activityGO:00508031280.012
positive regulation of cellular amino acid metabolic processGO:004576400.012
steroid catabolic processGO:000670610.012
ribonucleoside metabolic processGO:00091191270.012
positive regulation of transcription dna templatedGO:00458932660.012
purine ribonucleoside triphosphate metabolic processGO:00092051190.012
single organism membrane organizationGO:0044802930.012
regulation of i kappab kinase nf kappab signalingGO:004312220.012
photoreceptor cell developmentGO:0042461960.012
regulation of defense responseGO:00313471020.012
triglyceride biosynthetic processGO:001943220.012
positive regulation of protein metabolic processGO:00512471280.011
nucleoside metabolic processGO:00091161270.011
regulation of phosphorylationGO:00423251470.011
nucleoside triphosphate metabolic processGO:00091411200.011
membrane organizationGO:00610241120.011
synapse assemblyGO:00074161430.011
salivary gland cell autophagic cell deathGO:0035071830.011
cellular response to endogenous stimulusGO:0071495800.011
positive regulation of developmental processGO:00510941430.011
mrna metabolic processGO:00160711240.011
rna localizationGO:00064031150.011
embryonic axis specificationGO:00005781070.011
mapk cascadeGO:00001651070.011
cellular response to biotic stimulusGO:007121640.011
purine ribonucleotide metabolic processGO:00091501450.011
neutral lipid biosynthetic processGO:004646020.011
pigmentationGO:0043473750.011
ribonucleoside catabolic processGO:00424541120.011
purine nucleotide metabolic processGO:00061631460.011
female meiotic divisionGO:0007143700.011
histolysisGO:00075591020.011
ribonucleoside triphosphate metabolic processGO:00091991190.011
aggressive behaviorGO:0002118630.011
cellular response to dna damage stimulusGO:00069742230.011
detection of abiotic stimulusGO:0009582660.011
nephron developmentGO:007200630.011
purine nucleoside triphosphate metabolic processGO:00091441190.011
cellularizationGO:0007349900.011
salivary gland histolysisGO:0035070880.011
nephron epithelium developmentGO:007200930.011
positive regulation of cellular component organizationGO:00511301560.011
negative regulation of cell differentiationGO:00455961430.011
regulation of synapse assemblyGO:0051963940.011
tissue deathGO:00162711020.011
regulation of mitotic cell cycle phase transitionGO:19019901300.011
digestive tract developmentGO:00485651490.011
monocarboxylic acid transportGO:001571830.011
cell cycle phase transitionGO:00447701400.011
regulation of epithelial cell differentiationGO:003085640.011
wound healingGO:0042060750.011
positive regulation of phosphate metabolic processGO:00459371390.011
peptidyl amino acid modificationGO:00181931050.011
protein catabolic processGO:00301631010.011
eye photoreceptor cell developmentGO:0042462810.011
regulation of lipid transportGO:003236830.011
response to organic cyclic compoundGO:0014070890.011
purine ribonucleoside metabolic processGO:00461281270.011
detection of light stimulusGO:0009583580.011
reproductive behaviorGO:00190981220.011
cellular amide metabolic processGO:0043603800.011
pattern recognition receptor signaling pathwayGO:000222120.011
regulation of innate immune responseGO:0045088710.011
regulation of programmed cell deathGO:00430671520.011
secretionGO:00469031090.011
eye pigmentationGO:0048069430.011
positive regulation of phosphorus metabolic processGO:00105621390.011
purine nucleoside metabolic processGO:00422781270.011
establishment of organelle localizationGO:00516561220.011
acylglycerol biosynthetic processGO:004646320.011
membrane depolarizationGO:005189940.011
regulation of growthGO:00400082330.011
anion transmembrane transportGO:0098656260.011
mrna processingGO:00063971040.011
eye photoreceptor cell differentiationGO:00017541450.010
cellular lipid metabolic processGO:0044255830.010
anterior posterior axis specificationGO:00099481090.010
positive regulation of catabolic processGO:00098961050.010
negative regulation of rna biosynthetic processGO:19026792400.010
antimicrobial humoral responseGO:0019730990.010
positive regulation of catalytic activityGO:00430851180.010
maintenance of locationGO:0051235730.010
eye pigment metabolic processGO:0042441330.010
peptidyl threonine modificationGO:001821030.010
regulation of neurogenesisGO:00507671580.010
central nervous system developmentGO:00074172010.010
detection of chemical stimulusGO:0009593930.010
inorganic cation transmembrane transportGO:0098662610.010
regulation of phosphate metabolic processGO:00192202100.010
organic hydroxy compound metabolic processGO:1901615830.010
response to nitrogen compoundGO:1901698900.010
lipopolysaccharide mediated signaling pathwayGO:003166310.010
sulfur compound metabolic processGO:0006790590.010
sensory perception of painGO:001923340.010
cyclic purine nucleotide metabolic processGO:0052652250.010
leg disc morphogenesisGO:0007478800.010
agingGO:00075681430.010
purine nucleoside triphosphate catabolic processGO:00091461080.010
tube developmentGO:00352952440.010
cholesterol transportGO:003030120.010
regulation of gene expression epigeneticGO:00400291280.010
purine containing compound catabolic processGO:00725231120.010
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.010
epithelial cell migrationGO:00106311480.010
kidney morphogenesisGO:006099330.010
peptide metabolic processGO:0006518800.010
regulation of response to external stimulusGO:00321011150.010
regulation of cell morphogenesisGO:00226041630.010

rab3-GEF disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.052
cardiovascular system diseaseDOID:128700.022
disease of metabolismDOID:001466700.022
nervous system diseaseDOID:86300.021
artery diseaseDOID:005082800.018
vascular diseaseDOID:17800.018
inherited metabolic disorderDOID:65500.017
musculoskeletal system diseaseDOID:1700.015
acquired metabolic diseaseDOID:006015800.013
hypertensionDOID:1076300.013
sensory system diseaseDOID:005015500.013
urinary system diseaseDOID:1800.012
diabetes mellitusDOID:935100.012
carbohydrate metabolism diseaseDOID:005001300.012
glucose metabolism diseaseDOID:419400.012
disease of cellular proliferationDOID:1456600.012
cancerDOID:16200.012
organ system cancerDOID:005068600.011
eye and adnexa diseaseDOID:149200.011
eye diseaseDOID:561400.011
type 2 diabetes mellitusDOID:935200.011
renal tubular transport diseaseDOID:44700.010
kidney diseaseDOID:55700.010