Drosophila melanogaster

113 known processes

Ppcs (Dmel_CG5629)

Phosphopantothenoylcysteine synthetase

(Aliases: CG5629,Dmel\CG5629,anon-WO0118547.401,BcDNA:GH03502,GH03502,dPPCS,PPCS)

Ppcs biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
columnar cuboidal epithelial cell developmentGO:00020662490.908
cytoskeleton dependent cytokinesisGO:0061640810.838
germarium derived egg chamber formationGO:00072931010.813
ovarian follicle cell migrationGO:00072971210.759
organelle fissionGO:00482853400.620
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.605
cellular response to external stimulusGO:0071496660.593
negative regulation of cellular metabolic processGO:00313243820.556
cytoplasmic transport nurse cell to oocyteGO:0007303120.542
ovarian follicle cell developmentGO:00307072480.516
columnar cuboidal epithelial cell differentiationGO:00020652560.502
male gamete generationGO:00482322010.427
adult behaviorGO:00305341370.411
negative regulation of cellular biosynthetic processGO:00313272770.373
cytokinesisGO:0000910900.373
regulation of cellular protein metabolic processGO:00322682430.363
appendage developmentGO:00487364010.349
microtubule depolymerizationGO:0007019250.321
rhythmic processGO:00485111060.313
appendage morphogenesisGO:00351073970.294
imaginal disc derived wing morphogenesisGO:00074763370.280
macromolecular complex assemblyGO:00650032560.279
negative regulation of biosynthetic processGO:00098902770.275
imaginal disc derived appendage morphogenesisGO:00351143950.270
cell divisionGO:00513012480.261
regulation of organelle organizationGO:00330431960.254
positive regulation of nitrogen compound metabolic processGO:00511733540.245
response to organic substanceGO:00100332840.239
tissue migrationGO:00901301550.225
central nervous system developmentGO:00074172010.223
homeostatic processGO:00425921990.217
germ line cyst formationGO:0048134440.215
cognitionGO:00508901410.212
cellular response to nutrient levelsGO:0031669620.200
positive regulation of cellular biosynthetic processGO:00313283160.199
positive regulation of macromolecule metabolic processGO:00106044050.198
single organism behaviorGO:00447083910.197
epithelial cell developmentGO:00020642740.189
circadian rhythmGO:00076231050.186
positive regulation of rna metabolic processGO:00512542710.177
cellular response to extracellular stimulusGO:0031668640.176
spermatogenesisGO:00072832000.176
regulation of protein complex disassemblyGO:0043244290.173
positive regulation of nucleobase containing compound metabolic processGO:00459353320.168
cell proliferationGO:00082832990.166
response to extracellular stimulusGO:00099911160.165
epithelial cell differentiationGO:00308553220.164
regulation of protein metabolic processGO:00512462560.163
cellular response to starvationGO:0009267610.162
agingGO:00075681430.162
negative regulation of cell differentiationGO:00455961430.158
acylglycerol homeostasisGO:0055090190.157
actin filament based processGO:00300292200.155
regulation of multicellular organismal developmentGO:20000264140.152
regulation of cell cycle processGO:00105641810.151
regulation of cell cycleGO:00517262910.151
protein modification processGO:00362114380.144
morphogenesis of follicular epitheliumGO:0016333360.143
learning or memoryGO:00076111410.142
negative regulation of gene expressionGO:00106293870.137
chemical homeostasisGO:0048878920.134
wing disc morphogenesisGO:00074723440.130
female germ line cyst formationGO:0048135420.129
organonitrogen compound metabolic processGO:19015643180.126
regulation of transcription from rna polymerase ii promoterGO:00063573780.124
localization of cellGO:00516742570.121
cell migrationGO:00164772380.119
small molecule metabolic processGO:00442813050.119
organic substance catabolic processGO:19015753080.118
transcription from rna polymerase ii promoterGO:00063663680.118
dna packagingGO:0006323910.118
negative regulation of rna biosynthetic processGO:19026792400.118
catabolic processGO:00090564090.112
photoreceptor cell differentiationGO:00465301700.111
lipid homeostasisGO:0055088330.111
cellular protein modification processGO:00064644380.111
dendrite morphogenesisGO:00488131990.109
single organism membrane organizationGO:0044802930.109
negative regulation of nitrogen compound metabolic processGO:00511722650.107
regulation of cell differentiationGO:00455953020.105
positive regulation of gene expressionGO:00106282900.105
imaginal disc derived appendage developmentGO:00487373990.105
circadian behaviorGO:0048512760.102
regulation of microtubule polymerization or depolymerizationGO:0031110270.099
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.098
determination of adult lifespanGO:00083401370.097
response to alcoholGO:0097305950.097
negative regulation of cytoskeleton organizationGO:0051494300.095
compound eye photoreceptor cell differentiationGO:00017511400.093
membrane organizationGO:00610241120.092
negative regulation of macromolecule biosynthetic processGO:00105582700.092
gene silencingGO:00164581380.089
response to ethanolGO:0045471590.089
locomotory behaviorGO:00076261760.088
multicellular organismal agingGO:00102591400.088
negative regulation of protein complex disassemblyGO:0043242230.087
oocyte constructionGO:00073081120.085
cellular macromolecular complex assemblyGO:00346221530.085
vesicle mediated transportGO:00161923810.085
organic acid metabolic processGO:00060821030.085
actin cytoskeleton organizationGO:00300362060.084
compound eye morphogenesisGO:00017452490.084
intracellular transportGO:00469072280.084
positive regulation of protein metabolic processGO:00512471280.083
cellular response to organic substanceGO:00713101320.083
negative regulation of cell cycleGO:00457861160.082
regulation of cell divisionGO:0051302720.082
growthGO:00400073590.081
germarium derived female germ line cyst formationGO:0030727420.081
establishment of localization in cellGO:00516494020.081
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.079
positive regulation of response to stimulusGO:00485843230.079
apoptotic processGO:00069151590.079
oxoacid metabolic processGO:00434361030.079
oocyte axis specificationGO:00073091080.077
mitotic cytokinesisGO:0000281500.075
hematopoietic or lymphoid organ developmentGO:0048534570.074
cellular response to organic cyclic compoundGO:0071407320.074
compound eye developmentGO:00487493070.074
response to abiotic stimulusGO:00096283410.073
immune system developmentGO:0002520570.072
single organism intracellular transportGO:19025822070.072
regulation of protein depolymerizationGO:1901879270.071
cellular catabolic processGO:00442483720.071
regionalizationGO:00030024160.070
macromolecule catabolic processGO:00090571610.069
oocyte differentiationGO:00099941450.069
regulation of cell deathGO:00109411730.068
chorion containing eggshell formationGO:00073041050.068
stem cell differentiationGO:00488631170.068
body morphogenesisGO:001017120.067
negative regulation of cellular component organizationGO:00511291080.066
protein complex assemblyGO:00064612000.065
lipid metabolic processGO:00066291210.063
cellular macromolecule catabolic processGO:00442651360.063
learningGO:0007612750.063
positive regulation of developmental processGO:00510941430.063
endocytosisGO:00068973100.063
germarium derived oocyte fate determinationGO:0007294260.062
multi multicellular organism processGO:00447061230.062
post embryonic appendage morphogenesisGO:00351203850.062
dendrite developmentGO:00163582040.061
cell fate determinationGO:0001709910.060
negative regulation of developmental processGO:00510932010.060
dna conformation changeGO:00711031050.059
nuclear divisionGO:00002803320.059
negative regulation of rna metabolic processGO:00512532510.057
brain developmentGO:00074201200.057
developmental growthGO:00485892800.056
mitochondrial fusionGO:000805370.056
negative regulation of microtubule polymerization or depolymerizationGO:0031111210.056
associative learningGO:0008306650.056
regulation of catalytic activityGO:00507901850.055
positive regulation of cellular component organizationGO:00511301560.055
deathGO:00162652840.055
regulation of cell proliferationGO:00421271630.055
positive regulation of biosynthetic processGO:00098913160.054
oocyte developmentGO:00485991240.054
cellular response to chemical stimulusGO:00708871990.053
response to oxygen containing compoundGO:19017002000.053
negative regulation of protein depolymerizationGO:1901880230.052
carboxylic acid metabolic processGO:0019752920.052
cellular amine metabolic processGO:0044106120.052
regulation of mitotic cell cycleGO:00073461900.052
fusome organizationGO:0045478130.051
cytoplasmic transportGO:00164821300.051
eye morphogenesisGO:00485922600.050
adult locomotory behaviorGO:0008344760.050
negative regulation of microtubule depolymerizationGO:0007026210.050
chromosome organizationGO:00512763600.050
chromatin modificationGO:00165681470.049
embryo development ending in birth or egg hatchingGO:00097921520.049
amine metabolic processGO:0009308120.048
dorsal appendage formationGO:0046843470.046
negative regulation of cell proliferationGO:0008285690.046
epithelium migrationGO:00901321480.046
positive regulation of macromolecule biosynthetic processGO:00105572830.046
regulation of programmed cell deathGO:00430671520.045
positive regulation of cell communicationGO:00106472500.045
establishment or maintenance of polarity of follicular epitheliumGO:0016334260.045
ovarian follicle cell stalk formationGO:0030713170.044
cell motilityGO:00488702510.044
sensory organ precursor cell fate determinationGO:0016360190.043
determination of left right symmetryGO:000736890.043
meiosis iiGO:0007135230.042
regulation of localizationGO:00328792750.042
head developmentGO:00603221350.041
regulation of catabolic processGO:00098941700.040
protein catabolic processGO:00301631010.040
negative regulation of cell communicationGO:00106482230.040
response to ionizing radiationGO:0010212320.040
positive regulation of molecular functionGO:00440931360.040
positive regulation of rna biosynthetic processGO:19026802660.040
chromatin remodelingGO:0006338720.039
negative regulation of signalingGO:00230572190.039
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.038
positive regulation of signalingGO:00230562430.038
synaptic transmission dopaminergicGO:000196320.038
chromatin organizationGO:00063252070.038
negative regulation of nucleic acid templated transcriptionGO:19035072400.037
anterior posterior pattern specificationGO:00099521360.037
positive regulation of catabolic processGO:00098961050.037
enzyme linked receptor protein signaling pathwayGO:00071671790.037
meiotic cytokinesisGO:0033206330.036
regulation of gene expression epigeneticGO:00400291280.036
regulation of cellular amine metabolic processGO:003323830.036
negative regulation of cell cycle processGO:00109481090.036
regulation of response to stressGO:00801342000.035
cell type specific apoptotic processGO:0097285380.035
oocyte nucleus localization involved in oocyte dorsal ventral axis specificationGO:0051663120.035
programmed cell deathGO:00125012570.034
positive regulation of cellular catabolic processGO:0031331950.034
negative regulation of transcription dna templatedGO:00458922370.033
macroautophagyGO:0016236420.033
apoptotic signaling pathwayGO:0097190270.032
regulation of cellular amino acid metabolic processGO:000652100.032
cystoblast divisionGO:0007282100.032
negative regulation of multicellular organismal processGO:00512411420.032
regulation of phosphorus metabolic processGO:00511742100.032
positive regulation of programmed cell deathGO:0043068620.031
regulation of neurogenesisGO:00507671580.031
regulation of transferase activityGO:0051338580.031
germarium derived oocyte differentiationGO:0030706290.031
ovarian fusome organizationGO:0030723110.031
regulation of cytoskeleton organizationGO:0051493890.030
positive regulation of cellular protein metabolic processGO:00322701180.030
regulation of epithelial cell proliferationGO:005067840.030
negative regulation of response to stimulusGO:00485852580.030
nucleobase containing compound catabolic processGO:00346551650.030
negative regulation of cell cycle phase transitionGO:19019881030.029
regulation of synapse structure and activityGO:00508031280.029
dna metabolic processGO:00062592270.029
regulation of transportGO:00510491810.029
regulation of phosphorylationGO:00423251470.029
extracellular structure organizationGO:0043062460.029
regulation of microtubule based processGO:0032886490.029
regulation of immune system processGO:00026821760.028
organelle fusionGO:0048284460.028
digestive system developmentGO:00551231490.028
regulation of multi organism processGO:00439001310.028
cellular amino acid metabolic processGO:0006520610.028
regulation of anatomical structure morphogenesisGO:00226032420.028
negative regulation of cellular response to oxidative stressGO:190040810.028
epithelial cell migrationGO:00106311480.028
mitotic cell cycle phase transitionGO:00447721380.028
immune system processGO:00023763470.027
molting cycleGO:0042303560.027
organelle assemblyGO:00709251980.027
regulation of mitotic cell cycle phase transitionGO:19019901300.027
cellular component disassemblyGO:0022411460.026
regulation of developmental growthGO:00486381740.026
erbb signaling pathwayGO:0038127580.026
positive regulation of nucleic acid templated transcriptionGO:19035082660.026
oocyte anterior posterior axis specificationGO:0007314720.026
photoreceptor cell fate commitmentGO:0046552410.025
response to starvationGO:0042594970.025
regulation of apoptotic processGO:00429811300.025
negative regulation of programmed cell deathGO:0043069720.025
cell cycle arrestGO:000705040.025
proteolysisGO:00065081920.025
protein complex biogenesisGO:00702712010.025
regulation of phosphate metabolic processGO:00192202100.025
single organism cellular localizationGO:19025801800.025
ameboidal type cell migrationGO:00016671510.025
response to endogenous stimulusGO:00097191190.025
regulation of molecular functionGO:00650092170.025
segmentationGO:00352822070.024
positive regulation of multicellular organismal processGO:00512401430.024
response to nutrient levelsGO:00316671140.024
regulation of microtubule cytoskeleton organizationGO:0070507410.024
forebrain developmentGO:003090020.023
hindgut developmentGO:0061525580.023
regulation of cellular component biogenesisGO:00440872010.023
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281250.023
embryonic axis specificationGO:00005781070.022
positive regulation of phosphorus metabolic processGO:00105621390.022
negative regulation of protein metabolic processGO:0051248850.022
larval developmentGO:00021641040.022
macromolecular complex disassemblyGO:0032984370.022
multicellular organism growthGO:0035264460.022
cellular response to ionizing radiationGO:0071479150.022
embryonic pattern specificationGO:00098801740.022
muscle tissue morphogenesisGO:006041520.021
membrane fusionGO:0061025420.021
regulation of protein modification processGO:00313991120.021
mitotic nuclear divisionGO:00070672130.021
phosphorylationGO:00163102940.021
regulation of neuron deathGO:1901214260.021
actomyosin structure organizationGO:0031032560.020
muscle structure developmentGO:00610612240.020
generation of precursor metabolites and energyGO:0006091420.019
cellular response to nitrogen compoundGO:1901699510.019
apoptotic cell clearanceGO:0043277140.019
chromosome condensationGO:0030261410.019
intracellular protein transportGO:00068861040.019
regulation of spindle organizationGO:0090224170.019
tube developmentGO:00352952440.019
hemopoiesisGO:0030097460.019
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092380.019
positive regulation of hydrolase activityGO:0051345780.018
cell cycle phase transitionGO:00447701400.018
oocyte dorsal ventral axis specificationGO:0007310340.018
phenol containing compound metabolic processGO:0018958570.018
regulation of wnt signaling pathwayGO:0030111680.018
single organism biosynthetic processGO:00447112060.018
regulation of proteolysisGO:0030162870.018
regulation of cellular catabolic processGO:00313291570.018
eye developmentGO:00016543230.018
intracellular signal transductionGO:00355563000.018
protein k48 linked ubiquitinationGO:007093630.018
positive regulation of organelle organizationGO:0010638650.017
negative regulation of nucleobase containing compound metabolic processGO:00459342610.017
eye photoreceptor cell differentiationGO:00017541450.017
telencephalon developmentGO:002153720.017
anterior posterior axis specification embryoGO:00085951030.017
meiotic nuclear divisionGO:00071261510.017
positive regulation of catalytic activityGO:00430851180.017
defense responseGO:00069523000.017
oocyte localization involved in germarium derived egg chamber formationGO:0030720120.017
response to lipopolysaccharideGO:003249640.017
cellular response to endogenous stimulusGO:0071495800.017
eye photoreceptor cell fate commitmentGO:0042706370.016
negative regulation of cellular protein metabolic processGO:0032269850.016
sensory organ morphogenesisGO:00905962600.016
developmental maturationGO:00217001720.016
negative regulation of molecular functionGO:0044092510.016
cellular component assembly involved in morphogenesisGO:00109271510.016
regulation of nuclear divisionGO:0051783580.016
negative regulation of cell deathGO:0060548810.016
oocyte fate determinationGO:0030716270.015
morphogenesis of an epitheliumGO:00020092760.015
negative regulation of signal transductionGO:00099682060.015
muscle cell developmentGO:0055001500.015
blastoderm segmentationGO:00073501590.015
rhythmic behaviorGO:0007622760.015
purine nucleotide metabolic processGO:00061631460.015
organic substance transportGO:00717022570.015
response to oxidative stressGO:0006979860.015
protein phosphorylationGO:00064681690.015
response to nitrogen compoundGO:1901698900.014
neurological system processGO:00508773580.014
protein processingGO:0016485680.014
skeletal muscle fiber developmentGO:004874130.014
neuron apoptotic processGO:0051402170.014
meiotic cell cycle processGO:19030461320.014
axis specificationGO:00097981670.014
negative regulation of neuron apoptotic processGO:0043524140.014
regulation of cell developmentGO:00602842150.014
multi organism reproductive behaviorGO:00447051210.014
regulation of meiosisGO:004002030.014
protein depolymerizationGO:0051261310.014
cellular respirationGO:0045333260.014
heterochromatin organizationGO:0070828250.014
response to other organismGO:00517072930.014
response to organic cyclic compoundGO:0014070890.014
single organism carbohydrate metabolic processGO:0044723720.014
regulation of endocytosisGO:0030100370.014
negative regulation of organelle organizationGO:0010639560.014
proteolysis involved in cellular protein catabolic processGO:0051603830.013
positive regulation of apoptotic signaling pathwayGO:200123540.013
epidermal growth factor receptor signaling pathwayGO:0007173580.013
protein localization to organelleGO:0033365820.013
regulation of secretionGO:0051046440.013
positive regulation of cell deathGO:0010942690.013
positive regulation of transcription dna templatedGO:00458932660.013
cellular protein complex disassemblyGO:0043624350.013
regulation of chromosome organizationGO:0033044640.013
eggshell chorion assemblyGO:0007306660.013
negative regulation of mitotic cell cycleGO:00459301090.013
positive regulation of signal transductionGO:00099672230.013
carbohydrate metabolic processGO:0005975820.013
positive regulation of intracellular signal transductionGO:19025331160.013
circadian sleep wake cycleGO:0042745280.013
spermatid differentiationGO:00485151140.013
establishment of protein localizationGO:00451841630.013
rna processingGO:00063961470.013
regulation of cellular response to oxidative stressGO:190040740.013
negative regulation of cell divisionGO:0051782170.013
protein ubiquitinationGO:0016567700.012
protein maturationGO:0051604710.012
muscle cell differentiationGO:00426921030.012
positive regulation of multicellular organism growthGO:0040018210.012
aromatic compound catabolic processGO:00194391660.012
negative regulation of response to oxidative stressGO:190288310.012
triglyceride homeostasisGO:0070328180.012
spindle organizationGO:00070512530.012
energy derivation by oxidation of organic compoundsGO:0015980320.012
contractile ring contractionGO:0036213120.012
negative regulation of catalytic activityGO:0043086420.012
skin developmentGO:0043588650.012
response to ecdysoneGO:0035075340.012
cellular response to oxygen containing compoundGO:1901701790.012
regulation of endopeptidase activityGO:0052548360.012
establishment or maintenance of cell polarityGO:00071631670.012
mrna processingGO:00063971040.012
positive regulation of transportGO:0051050920.012
gastrulation involving germ band extensionGO:0010004360.012
microtubule polymerization or depolymerizationGO:0031109390.012
regulation of synaptic transmissionGO:0050804690.011
gland developmentGO:00487321910.011
lipid storageGO:0019915380.011
response to growth factorGO:0070848310.011
organonitrogen compound catabolic processGO:19015651280.011
spermatid developmentGO:0007286980.011
camera type eye developmentGO:004301040.011
cellular protein complex assemblyGO:0043623710.011
purine ribonucleoside metabolic processGO:00461281270.011
cell deathGO:00082192790.011
nuclear transportGO:0051169720.011
telomere maintenanceGO:0000723210.011
regulation of cell cycle phase transitionGO:19019871300.011
gonad developmentGO:0008406500.011
cellular response to organonitrogen compoundGO:0071417360.011
eye antennal disc developmentGO:0035214600.011
positive regulation of apoptotic processGO:0043065470.011
formation of organ boundaryGO:0010160300.011
cellular ketone metabolic processGO:0042180240.011
sex differentiationGO:0007548810.011
phagocytosisGO:00069092150.011
germ line stem cell maintenanceGO:0030718500.011
regulation of epidermal cell differentiationGO:004560430.011
respiratory system developmentGO:00605412130.011
cellular macromolecule localizationGO:00707272200.010
stress activated mapk cascadeGO:0051403520.010
compound eye photoreceptor developmentGO:0042051780.010
hindbrain developmentGO:003090220.010

Ppcs disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
central nervous system diseaseDOID:33100.048
disease of anatomical entityDOID:700.048
nervous system diseaseDOID:86300.048
parkinson s diseaseDOID:1433000.048
neurodegenerative diseaseDOID:128900.048
synucleinopathyDOID:005089000.048
disease of cellular proliferationDOID:1456600.014
cancerDOID:16200.014