IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

Dbi (Dmel_CG8627)

Diazepam-binding inhibitor

(Aliases: DBI,CG8627,Dmel\CG8627,BcDNA:RH39533,anon-WO0172774.131,ACBP)

Entrez: 38784
FLYBASE: FBgn0010387
UniProtKB: P42281

Process Predictions
Disease Predictions

Dbi biological process predictions

Show only novel predictionsHighlight processes of functional analogs

Filter by process size:

Biological process	GO term ID	Process size	Probability
immune response	GO:0006955	246	0.184
multi multicellular organism process	GO:0044706	123	0.072
small molecule metabolic process	GO:0044281	305	0.059
imaginal disc derived appendage development	GO:0048737	399	0.047
single organism biosynthetic process	GO:0044711	206	0.047
mating	GO:0007618	120	0.045
response to biotic stimulus	GO:0009607	294	0.042
multi organism behavior	GO:0051705	175	0.041
centrosome cycle	GO:0007098	137	0.040
cellular amino acid metabolic process	GO:0006520	61	0.040
regionalization	GO:0003002	416	0.037
microtubule organizing center organization	GO:0031023	168	0.036
mating behavior	GO:0007617	106	0.035
response to abiotic stimulus	GO:0009628	341	0.035
carboxylic acid metabolic process	GO:0019752	92	0.034
reproductive behavior	GO:0019098	122	0.034
gland development	GO:0048732	191	0.033
single organism catabolic process	GO:0044712	228	0.033
defense response	GO:0006952	300	0.033
defense response to bacterium	GO:0042742	178	0.033
neurological system process	GO:0050877	358	0.033
cellular ketone metabolic process	GO:0042180	24	0.032
immune system process	GO:0002376	347	0.031
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.031
developmental programmed cell death	GO:0010623	138	0.030
sterol homeostasis	GO:0055092	4	0.029
exocrine system development	GO:0035272	162	0.029
multicellular organismal reproductive behavior	GO:0033057	110	0.029
appendage development	GO:0048736	401	0.029
imaginal disc derived wing morphogenesis	GO:0007476	337	0.028
appendage morphogenesis	GO:0035107	397	0.028
cellular protein modification process	GO:0006464	438	0.027
response to organic substance	GO:0010033	284	0.027
amine metabolic process	GO:0009308	12	0.026
response to external biotic stimulus	GO:0043207	293	0.026
organic acid metabolic process	GO:0006082	103	0.026
cell recognition	GO:0008037	102	0.026
salivary gland cell autophagic cell death	GO:0035071	83	0.026
cellular catabolic process	GO:0044248	372	0.026
ethanolamine containing compound metabolic process	GO:0042439	4	0.025
protein modification process	GO:0036211	438	0.025
cellular amine metabolic process	GO:0044106	12	0.024
gland morphogenesis	GO:0022612	145	0.024
organic substance transport	GO:0071702	257	0.024
ecdysteroid metabolic process	GO:0045455	19	0.024
positive regulation of macromolecule metabolic process	GO:0010604	405	0.024
cellular response to chemical stimulus	GO:0070887	199	0.024
anion homeostasis	GO:0055081	3	0.024
innate immune response	GO:0045087	144	0.023
wing disc morphogenesis	GO:0007472	344	0.022
hormone catabolic process	GO:0042447	3	0.022
organonitrogen compound metabolic process	GO:1901564	318	0.022
male mating behavior	GO:0060179	70	0.021
homeostatic process	GO:0042592	199	0.021
autophagic cell death	GO:0048102	83	0.021
post embryonic appendage morphogenesis	GO:0035120	385	0.021
defense response to other organism	GO:0098542	225	0.020
camera type eye development	GO:0043010	4	0.020
regulation of anatomical structure morphogenesis	GO:0022603	242	0.020
regulation of cell differentiation	GO:0045595	302	0.020
lipid metabolic process	GO:0006629	121	0.020
cellular modified amino acid metabolic process	GO:0006575	45	0.019
adult behavior	GO:0030534	137	0.019
actin filament based process	GO:0030029	220	0.019
developmental growth	GO:0048589	280	0.019
sensory perception	GO:0007600	196	0.019
humoral immune response	GO:0006959	117	0.018
l amino acid import	GO:0043092	2	0.018
cell death	GO:0008219	279	0.018
cell adhesion	GO:0007155	136	0.018
negative regulation of cellular metabolic process	GO:0031324	382	0.018
regulation of multicellular organismal development	GO:2000026	414	0.018
salivary gland development	GO:0007431	162	0.017
circadian rhythm	GO:0007623	105	0.017
response to oxygen containing compound	GO:1901700	200	0.017
multi organism reproductive behavior	GO:0044705	121	0.017
neuron recognition	GO:0008038	101	0.017
nuclear division	GO:0000280	332	0.017
response to other organism	GO:0051707	293	0.017
growth	GO:0040007	359	0.017
positive regulation of response to stimulus	GO:0048584	323	0.017
positive regulation of gene expression	GO:0010628	290	0.016
salivary gland morphogenesis	GO:0007435	145	0.016
kidney development	GO:0001822	3	0.016
macromolecular complex assembly	GO:0065003	256	0.016
organic substance catabolic process	GO:1901575	308	0.016
regulation of intracellular signal transduction	GO:1902531	236	0.016
steroid catabolic process	GO:0006706	1	0.015
mesoderm development	GO:0007498	78	0.015
cellular nitrogen compound catabolic process	GO:0044270	165	0.015
defense response to gram negative bacterium	GO:0050829	94	0.015
programmed cell death	GO:0012501	257	0.015
protein complex assembly	GO:0006461	200	0.015
response to organophosphorus	GO:0046683	2	0.015
body morphogenesis	GO:0010171	2	0.015
actin filament organization	GO:0007015	126	0.015
negative regulation of response to stimulus	GO:0048585	258	0.015
catabolic process	GO:0009056	409	0.015
regulation of anatomical structure size	GO:0090066	163	0.014
maintenance of location	GO:0051235	73	0.014
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.014
death	GO:0016265	284	0.014
forebrain development	GO:0030900	2	0.014
rhythmic process	GO:0048511	106	0.014
syncytium formation by plasma membrane fusion	GO:0000768	43	0.014
connective tissue development	GO:0061448	3	0.014
cell aging	GO:0007569	2	0.014
epithelial cell development	GO:0002064	274	0.014
lipid homeostasis	GO:0055088	33	0.014
tissue death	GO:0016271	102	0.014
synaptic transmission	GO:0007268	288	0.014
lateral inhibition	GO:0046331	206	0.014
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.014
regulation of cellular amine metabolic process	GO:0033238	3	0.013
sulfur compound metabolic process	GO:0006790	59	0.013
columnar cuboidal epithelial cell development	GO:0002066	249	0.013
regulation of response to stress	GO:0080134	200	0.013
phosphorylation	GO:0016310	294	0.013
regulation of molecular function	GO:0065009	217	0.013
actin cytoskeleton organization	GO:0030036	206	0.013
salivary gland histolysis	GO:0035070	88	0.013
organonitrogen compound biosynthetic process	GO:1901566	117	0.013
protein complex biogenesis	GO:0070271	201	0.013
courtship behavior	GO:0007619	68	0.013
oxoacid metabolic process	GO:0043436	103	0.013
regulation of localization	GO:0032879	275	0.013
intracellular signal transduction	GO:0035556	300	0.013
muscle structure development	GO:0061061	224	0.013
ovarian follicle cell development	GO:0030707	248	0.013
response to bacterium	GO:0009617	198	0.013
meiotic cell cycle process	GO:1903046	132	0.013
regulation of cellular protein metabolic process	GO:0032268	243	0.013
positive regulation of signaling	GO:0023056	243	0.012
phagocytosis	GO:0006909	215	0.012
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.012
behavioral response to ethanol	GO:0048149	49	0.012
wound healing	GO:0042060	75	0.012
negative regulation of cell communication	GO:0010648	223	0.012
transmembrane transport	GO:0055085	139	0.012
carbohydrate derivative metabolic process	GO:1901135	217	0.012
regulation of catalytic activity	GO:0050790	185	0.012
purine nucleotide metabolic process	GO:0006163	146	0.012
vesicle mediated transport	GO:0016192	381	0.012
anatomical structure homeostasis	GO:0060249	97	0.012
regulation of protein metabolic process	GO:0051246	256	0.012
pigmentation	GO:0043473	75	0.012
organic hydroxy compound metabolic process	GO:1901615	83	0.012
regulation of cellular ketone metabolic process	GO:0010565	3	0.012
synaptic target recognition	GO:0008039	45	0.012
single organism behavior	GO:0044708	391	0.011
respiratory system development	GO:0060541	213	0.011
syncytium formation	GO:0006949	43	0.011
regulation of defense response	GO:0031347	102	0.011
regulation of developmental growth	GO:0048638	174	0.011
epithelial cell differentiation	GO:0030855	322	0.011
aging	GO:0007568	143	0.011
secondary metabolite biosynthetic process	GO:0044550	24	0.011
cellular response to organic substance	GO:0071310	132	0.011
response to temperature stimulus	GO:0009266	106	0.011
sensory perception of chemical stimulus	GO:0007606	116	0.011
transcription from rna polymerase ii promoter	GO:0006366	368	0.011
biological adhesion	GO:0022610	138	0.011
single organism intracellular transport	GO:1902582	207	0.011
organelle fission	GO:0048285	340	0.011
organophosphate metabolic process	GO:0019637	195	0.011
peptidoglycan recognition protein signaling pathway	GO:0061057	16	0.011
intracellular transport	GO:0046907	228	0.011
positive regulation of signal transduction	GO:0009967	223	0.011
positive regulation of cellular biosynthetic process	GO:0031328	316	0.011
multicellular organismal aging	GO:0010259	140	0.011
meiotic nuclear division	GO:0007126	151	0.011
aromatic compound catabolic process	GO:0019439	166	0.011
small molecule biosynthetic process	GO:0044283	37	0.011
response to starvation	GO:0042594	97	0.011
negative regulation of biosynthetic process	GO:0009890	277	0.011
response to endogenous stimulus	GO:0009719	119	0.010
positive regulation of biosynthetic process	GO:0009891	316	0.010
cellular response to dna damage stimulus	GO:0006974	223	0.010
eye development	GO:0001654	323	0.010
centrosome organization	GO:0051297	163	0.010
chemical homeostasis	GO:0048878	92	0.010
cell proliferation	GO:0008283	299	0.010
chromosome segregation	GO:0007059	157	0.010
morphogenesis of an epithelium	GO:0002009	276	0.010
taxis	GO:0042330	304	0.010
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.010
centrosome duplication	GO:0051298	121	0.010
hormone mediated signaling pathway	GO:0009755	16	0.010
cellular response to endogenous stimulus	GO:0071495	80	0.010
regulation of cell morphogenesis	GO:0022604	163	0.010
histolysis	GO:0007559	102	0.010
mitotic nuclear division	GO:0007067	213	0.010
positive regulation of cell communication	GO:0010647	250	0.010
spermatogenesis	GO:0007283	200	0.010

Dbi disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.065
acquired metabolic disease	DOID:0060158	0.016
disease of metabolism	DOID:0014667	0.016
amyloidosis	DOID:9120	0.016
familial visceral amyloidosis	DOID:0050636	0.016
nervous system disease	DOID:863	0.015
cardiovascular system disease	DOID:1287	0.012
disease of cellular proliferation	DOID:14566	0.011
cancer	DOID:162	0.011

Loading network...

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network