Drosophila melanogaster

55 known processes

wun2 (Dmel_CG8805)

wunen-2

(Aliases: LPP-like,Tunen,N14,CK02248,Wun2,WUN-like,wun-2,Pap2G,DrPAP2[G],Dmel\CG8805,CG8805,BEST:CK02248)

wun2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of growthGO:00400082330.252
developmental programmed cell deathGO:00106231380.229
nurse cell apoptotic processGO:0045476170.184
cellular component assembly involved in morphogenesisGO:00109271510.120
germ cell migrationGO:0008354430.119
programmed cell deathGO:00125012570.111
salivary gland morphogenesisGO:00074351450.109
eye photoreceptor cell differentiationGO:00017541450.101
growthGO:00400073590.096
salivary gland developmentGO:00074311620.095
regionalizationGO:00030024160.093
cell deathGO:00082192790.088
photoreceptor cell differentiationGO:00465301700.085
negative regulation of transcription dna templatedGO:00458922370.084
gland morphogenesisGO:00226121450.082
camera type eye morphogenesisGO:004859320.082
eye developmentGO:00016543230.080
synapse assemblyGO:00074161430.077
negative regulation of multicellular organismal processGO:00512411420.076
negative regulation of cellular metabolic processGO:00313243820.072
Mouse
response to abiotic stimulusGO:00096283410.069
Fly
exocrine system developmentGO:00352721620.067
apoptotic process involved in developmentGO:1902742200.066
negative regulation of gene expressionGO:00106293870.064
proteolysisGO:00065081920.064
negative regulation of nucleobase containing compound metabolic processGO:00459342610.063
cell type specific apoptotic processGO:0097285380.063
photoreceptor cell developmentGO:0042461960.061
negative regulation of nucleic acid templated transcriptionGO:19035072400.060
organic substance catabolic processGO:19015753080.060
amine metabolic processGO:0009308120.059
learningGO:0007612750.057
apoptotic processGO:00069151590.057
learning or memoryGO:00076111410.057
compound eye morphogenesisGO:00017452490.057
tissue deathGO:00162711020.054
regulation of cellular amine metabolic processGO:003323830.053
regulation of anatomical structure morphogenesisGO:00226032420.052
Fly
neurological system processGO:00508773580.051
embryonic pattern specificationGO:00098801740.051
deathGO:00162652840.051
negative regulation of cellular biosynthetic processGO:00313272770.050
regulation of response to stressGO:00801342000.048
Fly
camera type eye developmentGO:004301040.048
memoryGO:0007613940.047
embryonic morphogenesisGO:00485982060.047
Mouse
regulation of developmental growthGO:00486381740.047
ubiquitin dependent protein catabolic processGO:0006511780.047
synaptic growth at neuromuscular junctionGO:00511241190.046
negative regulation of growthGO:0045926840.046
developmental growthGO:00485892800.046
dendrite morphogenesisGO:00488131990.046
catabolic processGO:00090564090.045
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.045
response to other organismGO:00517072930.045
Fly
regulation of endopeptidase activityGO:0052548360.045
cognitionGO:00508901410.044
regulation of programmed cell deathGO:00430671520.044
regulation of proteolysisGO:0030162870.044
hair cell differentiationGO:0035315470.043
digestive system developmentGO:00551231490.043
Mouse
digestive tract morphogenesisGO:00485461270.043
Mouse
negative regulation of cellular component organizationGO:00511291080.042
stem cell differentiationGO:00488631170.042
salivary gland histolysisGO:0035070880.042
central nervous system developmentGO:00074172010.041
Mouse
salivary gland cell autophagic cell deathGO:0035071830.041
regulation of cellular component biogenesisGO:00440872010.041
histolysisGO:00075591020.041
regulation of embryonic developmentGO:0045995680.040
tube morphogenesisGO:00352391910.039
Mouse
negative regulation of rna metabolic processGO:00512532510.039
carboxylic acid metabolic processGO:0019752920.039
regulation of epithelial cell proliferationGO:005067840.039
cell junction organizationGO:0034330570.038
Fly
regulation of anatomical structure sizeGO:00900661630.038
axonogenesisGO:00074092900.038
mitotic sister chromatid segregationGO:0000070870.038
brain developmentGO:00074201200.037
protein localizationGO:00081042840.037
synapse organizationGO:00508081960.036
sensory organ morphogenesisGO:00905962600.036
chromosome separationGO:0051304420.035
intracellular signal transductionGO:00355563000.035
positive regulation of cell migrationGO:003033520.035
regulation of mitotic cell cycle phase transitionGO:19019901300.034
aromatic compound catabolic processGO:00194391660.034
positive regulation of multicellular organismal processGO:00512401430.034
organonitrogen compound metabolic processGO:19015643180.034
kidney developmentGO:000182230.034
cellular amine metabolic processGO:0044106120.033
respiratory system developmentGO:00605412130.033
Fly
eye morphogenesisGO:00485922600.033
detection of stimulusGO:00516061560.033
Fly
oxoacid metabolic processGO:00434361030.033
regulation of nervous system developmentGO:00519602480.033
single organism behaviorGO:00447083910.032
stem cell developmentGO:0048864790.032
response to external biotic stimulusGO:00432072930.032
Fly
establishment of tissue polarityGO:0007164870.031
Fly
negative regulation of rna biosynthetic processGO:19026792400.031
organelle assemblyGO:00709251980.031
endocytosisGO:00068973100.031
neuron recognitionGO:00080381010.031
organic acid metabolic processGO:00060821030.030
regulation of cell differentiationGO:00455953020.030
autophagic cell deathGO:0048102830.030
olfactory behaviorGO:0042048970.030
gliogenesisGO:0042063800.030
Mouse
negative regulation of nitrogen compound metabolic processGO:00511722650.029
positive regulation of cellular amino acid metabolic processGO:004576400.029
regulation of cell cycleGO:00517262910.029
cellular macromolecule catabolic processGO:00442651360.029
localization of cellGO:00516742570.029
retina development in camera type eyeGO:006004140.029
cellular catabolic processGO:00442483720.029
adult behaviorGO:00305341370.029
sulfur compound metabolic processGO:0006790590.028
positive regulation of compound eye retinal cell programmed cell deathGO:004667290.028
forebrain developmentGO:003090020.028
protein catabolic processGO:00301631010.028
single organism biosynthetic processGO:00447112060.028
mitotic cell cycle phase transitionGO:00447721380.028
epithelial cell developmentGO:00020642740.028
cell cell junction assemblyGO:0007043380.028
Fly
regulation of synaptic transmissionGO:0050804690.028
cellular component disassemblyGO:0022411460.028
chromosome segregationGO:00070591570.028
regulation of cell deathGO:00109411730.028
segmentationGO:00352822070.028
detection of stimulus involved in sensory perceptionGO:0050906920.028
negative regulation of developmental growthGO:0048640640.027
modification dependent macromolecule catabolic processGO:0043632790.027
compound eye retinal cell programmed cell deathGO:0046667230.027
transcription from rna polymerase ii promoterGO:00063663680.027
regulation of cellular protein metabolic processGO:00322682430.027
Mouse
small molecule metabolic processGO:00442813050.026
methylationGO:0032259470.026
positive regulation of cell motilityGO:200014730.026
digestive tract developmentGO:00485651490.026
Mouse
mitotic sister chromatid separationGO:0051306300.026
vesicle mediated transportGO:00161923810.025
enzyme linked receptor protein signaling pathwayGO:00071671790.025
response to ethanolGO:0045471590.025
eggshell formationGO:00307031050.025
chemosensory behaviorGO:00076351060.025
regulation of cellular catabolic processGO:00313291570.025
immune system processGO:00023763470.025
Fly
eye photoreceptor cell developmentGO:0042462810.025
regulation of cell projection organizationGO:0031344920.025
positive regulation of cellular amine metabolic processGO:003324000.025
cellular nitrogen compound catabolic processGO:00442701650.025
regulation of immune responseGO:00507761180.025
Fly
regulation of catalytic activityGO:00507901850.024
nephron developmentGO:007200630.024
response to radiationGO:00093141550.024
Fly
positive regulation of chromosome segregationGO:0051984100.024
protein maturationGO:0051604710.024
regulation of multicellular organismal developmentGO:20000264140.024
Fly
response to oxygen containing compoundGO:19017002000.024
sister chromatid segregationGO:0000819920.024
positive regulation of developmental processGO:00510941430.023
regulation of catabolic processGO:00098941700.023
protein modification processGO:00362114380.023
Mouse
zymogen activationGO:0031638200.023
cell projection assemblyGO:0030031940.023
negative regulation of programmed cell deathGO:0043069720.023
regulation of cellular component sizeGO:0032535980.023
gland developmentGO:00487321910.023
kidney epithelium developmentGO:007207330.023
negative regulation of organelle organizationGO:0010639560.023
positive regulation of signal transductionGO:00099672230.022
axis specificationGO:00097981670.022
cell cell junction organizationGO:0045216550.022
Fly
development of primary sexual characteristicsGO:0045137500.022
regulation of phosphate metabolic processGO:00192202100.022
Mouse
anterior posterior pattern specificationGO:00099521360.022
actin filament depolymerizationGO:003004250.022
regulation of innate immune responseGO:0045088710.022
Fly
ovarian follicle cell developmentGO:00307072480.022
gastrulation with mouth forming firstGO:0001703360.022
nuclear transcribed mrna catabolic process nonsense mediated decayGO:000018480.022
telencephalon developmentGO:002153720.022
imaginal disc derived appendage developmentGO:00487373990.022
regulation of cell cycle processGO:00105641810.022
anatomical structure homeostasisGO:0060249970.021
antimicrobial humoral responseGO:0019730990.021
regulation of synapse organizationGO:00508071100.021
cell junction assemblyGO:0034329420.021
Fly
regulation of cell developmentGO:00602842150.021
regulation of apoptotic processGO:00429811300.021
hematopoietic or lymphoid organ developmentGO:0048534570.020
positive regulation of transcription dna templatedGO:00458932660.020
regulation of organelle organizationGO:00330431960.020
regulation of molecular functionGO:00650092170.020
Mouse
embryonic development via the syncytial blastodermGO:00017001480.020
positive regulation of nitrogen compound metabolic processGO:00511733540.020
nuclear divisionGO:00002803320.020
macromolecule catabolic processGO:00090571610.020
nitrogen compound transportGO:0071705850.020
positive regulation of signalingGO:00230562430.020
cell migrationGO:00164772380.020
cuticle developmentGO:0042335860.019
developmental pigmentationGO:0048066680.019
homeostatic processGO:00425921990.019
regulation of transportGO:00510491810.019
dephosphorylationGO:0016311510.019
ncrna 3 end processingGO:0043628170.019
response to starvationGO:0042594970.019
meiotic nuclear divisionGO:00071261510.019
regulation of chromosome organizationGO:0033044640.019
embryo development ending in birth or egg hatchingGO:00097921520.019
regulation of synapse assemblyGO:0051963940.019
regulation of sister chromatid segregationGO:0033045280.019
positive regulation of rna metabolic processGO:00512542710.019
regulation of mitotic metaphase anaphase transitionGO:0030071260.019
positive regulation of phosphorus metabolic processGO:00105621390.019
Mouse
heterocycle catabolic processGO:00467001660.019
negative regulation of cell deathGO:0060548810.019
cell recognitionGO:00080371020.019
cell cycle checkpointGO:0000075950.019
establishment or maintenance of cytoskeleton polarityGO:0030952440.018
modification dependent protein catabolic processGO:0019941780.018
establishment or maintenance of bipolar cell polarityGO:0061245340.018
synaptic transmissionGO:00072682880.018
regulation of autophagyGO:0010506620.018
activation of cysteine type endopeptidase activityGO:0097202170.018
regulation of response to external stimulusGO:00321011150.018
regulation of dna templated transcription in response to stressGO:004362040.018
morphogenesis of an epitheliumGO:00020092760.018
Fly
olfactory learningGO:0008355560.018
cellular amino acid metabolic processGO:0006520610.018
regulation of compound eye retinal cell programmed cell deathGO:0046669180.018
negative regulation of biosynthetic processGO:00098902770.018
oocyte maturationGO:000155630.018
single organism catabolic processGO:00447122280.017
cellular response to hexose stimulusGO:007133110.017
regulation of hydrolase activityGO:0051336970.017
gastrulation involving germ band extensionGO:0010004360.017
cellular protein modification processGO:00064644380.017
Mouse
nucleobase containing compound catabolic processGO:00346551650.017
immune response activating signal transductionGO:000275720.017
associative learningGO:0008306650.017
regulation of synapse structure and activityGO:00508031280.017
positive regulation of jun kinase activityGO:004350740.017
aminoglycan biosynthetic processGO:0006023110.017
histone modificationGO:00165701060.017
cell growthGO:00160491080.017
defense response to other organismGO:00985422250.017
Fly
cell motilityGO:00488702510.017
developmental maturationGO:00217001720.017
actin filament based processGO:00300292200.017
morphogenesis of a polarized epitheliumGO:0001738930.016
Fly
nephron epithelium developmentGO:007200930.016
axon developmentGO:00615642970.016
canonical wnt signaling pathwayGO:0060070210.016
Mouse
regulation of cell divisionGO:0051302720.016
cellular response to radiationGO:0071478520.016
gastrulationGO:0007369700.016
Mouse
neuron projection guidanceGO:00974852410.016
cytokinesisGO:0000910900.016
long term memoryGO:0007616620.016
cilium morphogenesisGO:0060271390.016
proteolysis involved in cellular protein catabolic processGO:0051603830.016
cellular ketone metabolic processGO:0042180240.016
non sensory hair organizationGO:0035316470.016
regulation of localizationGO:00328792750.016
compound eye developmentGO:00487493070.016
regulation of phosphorus metabolic processGO:00511742100.016
Mouse
positive regulation of cellular catabolic processGO:0031331950.016
cell divisionGO:00513012480.016
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919160.016
regulation of cysteine type endopeptidase activityGO:2000116270.016
regulation of mitotic sister chromatid separationGO:0010965280.015
sensory perceptionGO:00076001960.015
ribose phosphate metabolic processGO:00196931450.015
regulation of membrane potentialGO:0042391350.015
regulation of cell cycle phase transitionGO:19019871300.015
protein complex disassemblyGO:0043241360.015
detection of external stimulusGO:0009581660.015
Fly
cellular response to peptide hormone stimulusGO:0071375280.015
ion transportGO:00068111450.015
dna alkylationGO:000630540.015
blastoderm segmentationGO:00073501590.015
protein processingGO:0016485680.015
epidermis developmentGO:0008544650.015
response to bacteriumGO:00096171980.015
Fly
aminoglycan metabolic processGO:0006022180.015
regulation of protein metabolic processGO:00512462560.015
Mouse
axis elongationGO:000340130.015
retinal cell programmed cell deathGO:0046666250.014
macromolecule methylationGO:0043414450.014
negative regulation of fibroblast growth factor receptor signaling pathwayGO:004003720.014
defense response to bacteriumGO:00427421780.014
Fly
protein heterooligomerizationGO:005129140.014
positive regulation of cellular component organizationGO:00511301560.014
negative regulation of cellular response to oxidative stressGO:190040810.014
synaptic vesicle localizationGO:0097479530.014
response to organophosphorusGO:004668320.014
positive regulation of immune responseGO:0050778630.014
negative regulation of cell differentiationGO:00455961430.014
imaginal disc pattern formationGO:0007447910.014
establishment of planar polarityGO:0001736870.014
Fly
defense responseGO:00069523000.014
Fly
chaeta developmentGO:0022416970.014
negative regulation of cell communicationGO:00106482230.014
negative regulation of immune system processGO:0002683500.014
Fly
muscle organ developmentGO:00075171270.014
regulation of cellular amino acid metabolic processGO:000652100.014
actin cytoskeleton organizationGO:00300362060.014
multicellular organismal agingGO:00102591400.014
phagocytosisGO:00069092150.014
regulation of defense responseGO:00313471020.014
Fly
positive regulation of catalytic activityGO:00430851180.014
extrinsic apoptotic signaling pathwayGO:009719110.014
response to hexoseGO:000974630.014
regulation of nuclear divisionGO:0051783580.014
negative regulation of developmental processGO:00510932010.013
response to alcoholGO:0097305950.013
regulation of metaphase anaphase transition of cell cycleGO:1902099260.013
somatic muscle developmentGO:0007525660.013
regulation of intracellular signal transductionGO:19025312360.013
regulation of peptidase activityGO:0052547390.013
regulation of cell sizeGO:0008361630.013
positive regulation of cellular biosynthetic processGO:00313283160.013
cilium assemblyGO:0042384380.013
humoral immune responseGO:00069591170.013
regulation of protein localizationGO:0032880760.013
sarcomere organizationGO:0045214260.013
membrane organizationGO:00610241120.013
compound eye photoreceptor cell differentiationGO:00017511400.013
immune responseGO:00069552460.013
Fly
anterior posterior axis specificationGO:00099481090.013
macromolecular complex disassemblyGO:0032984370.013
positive regulation of apoptotic signaling pathwayGO:200123540.013
imaginal disc derived wing morphogenesisGO:00074763370.013
regulation of meiosisGO:004002030.013
nephron epithelium morphogenesisGO:007208830.013
regulation of mitotic cell cycleGO:00073461900.013
regulation of retinal cell programmed cell deathGO:0046668180.013
negative regulation of response to oxidative stressGO:190288310.013
cell cycle phase transitionGO:00447701400.012
organic substance transportGO:00717022570.012
reproductive system developmentGO:0061458740.012
ribonucleoside catabolic processGO:00424541120.012
positive regulation of autophagyGO:0010508210.012
wound healingGO:0042060750.012
positive regulation of cell communicationGO:00106472500.012
appendage morphogenesisGO:00351073970.012
tissue morphogenesisGO:00487292970.012
Fly
regulation of protein depolymerizationGO:1901879270.012
epithelial cell differentiationGO:00308553220.012
positive regulation of intracellular signal transductionGO:19025331160.012
cellular response to dna damage stimulusGO:00069742230.012
head developmentGO:00603221350.012
regulation of neuron deathGO:1901214260.012
transmembrane transportGO:00550851390.012
apoptotic signaling pathwayGO:0097190270.012
defense response to gram negative bacteriumGO:0050829940.012
Fly
myofibril assemblyGO:0030239360.012
negative regulation of nervous system developmentGO:0051961920.012
regulation of mitotic sister chromatid segregationGO:0033047280.012
positive regulation of macroautophagyGO:001623980.012
cellular response to molecule of bacterial originGO:007121930.012
purine ribonucleotide metabolic processGO:00091501450.012
columnar cuboidal epithelial cell developmentGO:00020662490.012
wnt signaling pathwayGO:0016055980.012
Mouse
regulation of cellular component movementGO:0051270420.012
chorion containing eggshell formationGO:00073041050.012
sex differentiationGO:0007548810.012
negative regulation of reactive oxygen species metabolic processGO:200037810.012
regulation of multicellular organism growthGO:0040014400.012
negative regulation of intracellular signal transductionGO:1902532570.012
hematopoietic progenitor cell differentiationGO:000224410.012
biological adhesionGO:00226101380.012
Mouse
protein alkylationGO:0008213430.012
rna 3 end processingGO:0031123450.012
reactive oxygen species metabolic processGO:0072593220.012
positive regulation of programmed cell deathGO:0043068620.012
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281250.012
nephron tubule morphogenesisGO:007207830.011
epidermal growth factor receptor signaling pathwayGO:0007173580.011
response to extracellular stimulusGO:00099911160.011
regulation of synaptic growth at neuromuscular junctionGO:0008582890.011
cellular protein catabolic processGO:0044257830.011
purine ribonucleoside metabolic processGO:00461281270.011
post embryonic appendage morphogenesisGO:00351203850.011
gene silencingGO:00164581380.011
oocyte microtubule cytoskeleton polarizationGO:0008103220.011
regulation of tube length open tracheal systemGO:0035159240.011
cell maturationGO:00484691440.011
determination of adult lifespanGO:00083401370.011
eggshell chorion assemblyGO:0007306660.011
posttranscriptional gene silencing by rnaGO:0035194450.011
regulation of actin filament depolymerizationGO:003083430.011
negative regulation of neuron deathGO:1901215180.011
negative regulation of neuron apoptotic processGO:0043524140.011
negative regulation of cell proliferationGO:0008285690.011
cardiovascular system developmentGO:0072358820.011
Mouse
regulation of protein complex disassemblyGO:0043244290.011
microtubule polymerization or depolymerizationGO:0031109390.011
apical junction assemblyGO:0043297320.011
Fly
positive regulation of rna biosynthetic processGO:19026802660.011
phosphorylationGO:00163102940.011
Mouse
cytoplasmic microtubule organizationGO:0031122220.011
open tracheal system developmentGO:00074242040.011
Fly
appendage developmentGO:00487364010.011
rna processingGO:00063961470.011
metaphase anaphase transition of cell cycleGO:0044784280.011
anterior posterior axis specification embryoGO:00085951030.011
cell adhesionGO:00071551360.011
Mouse
kidney morphogenesisGO:006099330.011
negative regulation of macromolecule biosynthetic processGO:00105582700.011
cell cell signaling involved in cell fate commitmentGO:00451682100.011
response to lipopolysaccharideGO:003249640.011
mucopolysaccharide metabolic processGO:190351050.011
agingGO:00075681430.011
columnar cuboidal epithelial cell differentiationGO:00020652560.011
positive regulation of molecular functionGO:00440931360.011
Mouse
regulation of mrna processingGO:0050684710.011
posttranscriptional gene silencingGO:0016441460.011
cellular response to biotic stimulusGO:007121640.011
protein complex assemblyGO:00064612000.011
phosphatidylethanolamine metabolic processGO:004633710.011
mrna splicing via spliceosomeGO:0000398730.011
purine ribonucleoside triphosphate metabolic processGO:00092051190.011
organelle localizationGO:00516401480.011
regulation of transcription from rna polymerase ii promoterGO:00063573780.011
apoptotic process involved in morphogenesisGO:006056130.011
positive regulation of developmental growthGO:0048639620.011
regulation of erbb signaling pathwayGO:1901184420.011
notum morphogenesisGO:004880240.010
hemocyte migrationGO:0035099190.010
gtp metabolic processGO:0046039720.010
positive regulation of mitotic metaphase anaphase transitionGO:0045842100.010
secretion by cellGO:00329401010.010
positive regulation of neuron apoptotic processGO:004352510.010
negative regulation of catalytic activityGO:0043086420.010
connective tissue developmentGO:006144830.010
cellular protein complex disassemblyGO:0043624350.010
cellular response to nitrogen compoundGO:1901699510.010
germ line stem cell maintenanceGO:0030718500.010
response to x rayGO:001016580.010
response to woundingGO:0009611940.010
cuticle pattern formationGO:0035017270.010
oocyte microtubule cytoskeleton organizationGO:0016325350.010
mrna catabolic processGO:0006402330.010
cranial nerve developmentGO:002154510.010
erbb signaling pathwayGO:0038127580.010
regulation of cellular response to oxidative stressGO:190040740.010
epidermal cell differentiationGO:0009913510.010
negative regulation of mitotic cell cycle phase transitionGO:19019911030.010

wun2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
urinary system diseaseDOID:1800.045
disease of anatomical entityDOID:700.045
disease of cellular proliferationDOID:1456600.019
eye diseaseDOID:561400.012
sensory system diseaseDOID:005015500.012
eye and adnexa diseaseDOID:149200.012
nervous system diseaseDOID:86300.012
cancerDOID:16200.012