Drosophila melanogaster

0 known processes

TfIIS (Dmel_CG3710)

RNA polymerase II elongation factor

(Aliases: l(2)35cF,TFIIS,l(2)br52,Dmel\CG3710,RnpSII,DmSII,br52,l(2)35Cf,TFIISA,DmS-II,BG:DS00929.12,CG3710,TFS-II,l35Cf)

TfIIS biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
appendage morphogenesisGO:00351073970.163
imaginal disc derived appendage morphogenesisGO:00351143950.149
positive regulation of macromolecule metabolic processGO:00106044050.136
Rat
positive regulation of gene expressionGO:00106282900.104
Rat
wing disc morphogenesisGO:00074723440.100
appendage developmentGO:00487364010.099
negative regulation of cellular metabolic processGO:00313243820.098
imaginal disc derived appendage developmentGO:00487373990.094
cellular catabolic processGO:00442483720.089
post embryonic appendage morphogenesisGO:00351203850.088
positive regulation of nucleobase containing compound metabolic processGO:00459353320.081
Rat
regulation of anatomical structure morphogenesisGO:00226032420.080
phosphorylationGO:00163102940.072
positive regulation of nucleic acid templated transcriptionGO:19035082660.069
Rat
regulation of cell cycle phase transitionGO:19019871300.069
negative regulation of cellular component organizationGO:00511291080.067
regulation of cellular component biogenesisGO:00440872010.062
negative regulation of gene expressionGO:00106293870.062
positive regulation of rna metabolic processGO:00512542710.060
Rat
response to organic substanceGO:00100332840.058
regulation of organelle organizationGO:00330431960.058
organelle fissionGO:00482853400.057
organelle assemblyGO:00709251980.056
rna splicing via transesterification reactionsGO:0000375730.054
organic substance catabolic processGO:19015753080.051
rna localizationGO:00064031150.049
small molecule metabolic processGO:00442813050.048
imaginal disc derived wing morphogenesisGO:00074763370.048
catabolic processGO:00090564090.047
oxoacid metabolic processGO:00434361030.047
intracellular transportGO:00469072280.047
regulation of mitotic cell cycleGO:00073461900.046
cell cycle checkpointGO:0000075950.046
regulation of mitotic cell cycle phase transitionGO:19019901300.045
negative regulation of cell differentiationGO:00455961430.044
regulation of cellular catabolic processGO:00313291570.044
taxisGO:00423303040.044
modification dependent macromolecule catabolic processGO:0043632790.044
cellular macromolecule catabolic processGO:00442651360.043
negative regulation of developmental processGO:00510932010.043
small gtpase mediated signal transductionGO:0007264880.042
negative regulation of cell cycle processGO:00109481090.041
negative regulation of rna biosynthetic processGO:19026792400.041
neurological system processGO:00508773580.040
positive regulation of cellular biosynthetic processGO:00313283160.040
Rat
regulation of cell differentiationGO:00455953020.040
macromolecule catabolic processGO:00090571610.039
positive regulation of organelle organizationGO:0010638650.039
chromatin modificationGO:00165681470.039
cell proliferationGO:00082832990.039
chromatin organizationGO:00063252070.038
single organism biosynthetic processGO:00447112060.038
cell divisionGO:00513012480.038
organic substance transportGO:00717022570.038
negative regulation of cellular biosynthetic processGO:00313272770.038
mitotic spindle organizationGO:00070522200.038
phagocytosisGO:00069092150.037
positive regulation of cellular component organizationGO:00511301560.037
mitotic cell cycle phase transitionGO:00447721380.036
organonitrogen compound metabolic processGO:19015643180.036
regulation of proteasomal protein catabolic processGO:0061136390.036
regulation of cellular protein metabolic processGO:00322682430.035
regulation of cell cycleGO:00517262910.035
connective tissue developmentGO:006144830.035
mrna metabolic processGO:00160711240.035
compound eye developmentGO:00487493070.035
stem cell developmentGO:0048864790.035
cellular protein modification processGO:00064644380.035
establishment of localization in cellGO:00516494020.034
eye morphogenesisGO:00485922600.034
positive regulation of cellular amino acid metabolic processGO:004576400.033
mitotic sister chromatid separationGO:0051306300.033
negative regulation of cell cycleGO:00457861160.033
transcription from rna polymerase ii promoterGO:00063663680.033
Rat
regulation of multicellular organismal developmentGO:20000264140.033
nucleocytoplasmic transportGO:0006913720.033
cell cycle phase transitionGO:00447701400.032
positive regulation of cellular component biogenesisGO:0044089800.032
regulation of mrna processingGO:0050684710.032
positive regulation of signalingGO:00230562430.032
cellular macromolecule localizationGO:00707272200.032
eye developmentGO:00016543230.032
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.031
lateral inhibitionGO:00463312060.031
negative regulation of biosynthetic processGO:00098902770.031
negative regulation of macromolecule biosynthetic processGO:00105582700.031
positive regulation of nitrogen compound metabolic processGO:00511733540.031
Rat
cellular amine metabolic processGO:0044106120.031
positive regulation of cellular amine metabolic processGO:003324000.031
regulation of protein metabolic processGO:00512462560.031
ras protein signal transductionGO:0007265880.030
morphogenesis of an epitheliumGO:00020092760.030
mrna processingGO:00063971040.030
negative regulation of response to stimulusGO:00485852580.030
mitotic cell cycle checkpointGO:0007093880.030
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.029
Rat
anatomical structure homeostasisGO:0060249970.029
nucleobase containing compound catabolic processGO:00346551650.029
regulation of phosphate metabolic processGO:00192202100.029
response to nitrogen compoundGO:1901698900.029
growthGO:00400073590.028
dna templated transcription elongationGO:0006354180.028
regulation of phosphorus metabolic processGO:00511742100.028
homeostatic processGO:00425921990.028
regulation of intracellular signal transductionGO:19025312360.028
chromosome organizationGO:00512763600.028
cell cell signaling involved in cell fate commitmentGO:00451682100.028
regulation of mrna metabolic processGO:1903311720.028
single organism behaviorGO:00447083910.028
positive regulation of macromolecule biosynthetic processGO:00105572830.028
Rat
cellular response to hormone stimulusGO:0032870440.028
vesicle mediated transportGO:00161923810.028
organic acid metabolic processGO:00060821030.028
regulation of cell proliferationGO:00421271630.027
proteasomal protein catabolic processGO:0010498590.027
regulation of chromatin silencingGO:0031935360.027
organophosphate metabolic processGO:00196371950.027
negative regulation of cell divisionGO:0051782170.027
gene silencingGO:00164581380.027
cell deathGO:00082192790.027
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434370.027
glycoprotein biosynthetic processGO:0009101410.027
macromolecular complex assemblyGO:00650032560.027
developmental growthGO:00485892800.027
intracellular signal transductionGO:00355563000.026
negative regulation of mitotic cell cycleGO:00459301090.026
positive regulation of cellular catabolic processGO:0031331950.026
protein modification processGO:00362114380.026
negative regulation of organelle organizationGO:0010639560.026
regulation of small gtpase mediated signal transductionGO:0051056930.026
positive regulation of cell communicationGO:00106472500.026
rna processingGO:00063961470.026
carbohydrate derivative metabolic processGO:19011352170.026
regulation of transcription from rna polymerase ii promoterGO:00063573780.026
Rat
stem cell differentiationGO:00488631170.026
response to abiotic stimulusGO:00096283410.025
imaginal disc derived leg morphogenesisGO:0007480800.025
regulation of proteolysisGO:0030162870.025
camera type eye developmentGO:004301040.025
metaphase anaphase transition of cell cycleGO:0044784280.025
regulation of mitotic metaphase anaphase transitionGO:0030071260.025
g protein coupled receptor signaling pathwayGO:00071861360.025
cellular ketone metabolic processGO:0042180240.025
endocytosisGO:00068973100.025
cellular response to dna damage stimulusGO:00069742230.025
regulation of sister chromatid segregationGO:0033045280.025
cellular protein localizationGO:00346131600.024
sensory organ morphogenesisGO:00905962600.024
rna splicingGO:0008380830.024
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.024
regulation of gene silencingGO:0060968630.024
rho protein signal transductionGO:0007266140.024
regulation of cell cycle processGO:00105641810.024
embryonic morphogenesisGO:00485982060.024
digestive tract morphogenesisGO:00485461270.024
dna metabolic processGO:00062592270.024
regulation of metaphase anaphase transition of cell cycleGO:1902099260.024
cilium assemblyGO:0042384380.023
carbohydrate derivative biosynthetic processGO:1901137850.023
spindle organizationGO:00070512530.023
positive regulation of response to stimulusGO:00485843230.023
regulation of mitotic sister chromatid segregationGO:0033047280.023
stem cell divisionGO:0017145690.023
amine metabolic processGO:0009308120.022
regulation of immune system processGO:00026821760.022
ubiquitin dependent protein catabolic processGO:0006511780.022
regulation of chromosome organizationGO:0033044640.022
negative regulation of rna metabolic processGO:00512532510.022
protein catabolic processGO:00301631010.022
regulation of catabolic processGO:00098941700.022
response to oxygen containing compoundGO:19017002000.022
regulation of cellular protein catabolic processGO:1903362440.022
cellular amino acid metabolic processGO:0006520610.022
body morphogenesisGO:001017120.022
protein localizationGO:00081042840.021
central nervous system developmentGO:00074172010.021
neural precursor cell proliferationGO:0061351750.021
response to endogenous stimulusGO:00097191190.021
negative regulation of nucleobase containing compound metabolic processGO:00459342610.021
single organism catabolic processGO:00447122280.021
forebrain developmentGO:003090020.021
rna transportGO:0050658460.021
regulation of dna metabolic processGO:0051052340.021
proteolysisGO:00065081920.021
regulation of mrna splicing via spliceosomeGO:0048024640.021
regulation of protein catabolic processGO:0042176550.021
dorsal ventral pattern formationGO:00099531330.021
nuclear transportGO:0051169720.021
positive regulation of biosynthetic processGO:00098913160.021
Rat
mitotic g2 dna damage checkpointGO:0007095690.021
proteolysis involved in cellular protein catabolic processGO:0051603830.020
negative regulation of cell cycle phase transitionGO:19019881030.020
response to dsrnaGO:0043331150.020
cellular macromolecular complex assemblyGO:00346221530.020
digestive system developmentGO:00551231490.020
multi multicellular organism processGO:00447061230.020
telencephalon developmentGO:002153720.020
negative regulation of protein metabolic processGO:0051248850.020
regulation of mitotic sister chromatid separationGO:0010965280.020
positive regulation of signal transductionGO:00099672230.020
positive regulation of transcription dna templatedGO:00458932660.020
Rat
stem cell maintenanceGO:0019827670.020
cellular protein catabolic processGO:0044257830.020
gland developmentGO:00487321910.020
enzyme linked receptor protein signaling pathwayGO:00071671790.019
actin filament based processGO:00300292200.019
carboxylic acid metabolic processGO:0019752920.019
compound eye morphogenesisGO:00017452490.019
aromatic compound catabolic processGO:00194391660.019
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377730.019
retina development in camera type eyeGO:006004140.019
rna phosphodiester bond hydrolysisGO:0090501170.019
erk1 and erk2 cascadeGO:0070371390.019
deathGO:00162652840.019
regulation of alternative mrna splicing via spliceosomeGO:0000381600.019
gastrulation involving germ band extensionGO:0010004360.019
establishment of rna localizationGO:0051236470.019
response to organonitrogen compoundGO:0010243750.019
response to other organismGO:00517072930.019
neural retina developmentGO:000340740.019
regulation of nervous system developmentGO:00519602480.018
immune system processGO:00023763470.018
tube morphogenesisGO:00352391910.018
chromatin silencingGO:0006342760.018
regulation of mitosisGO:0007088560.018
positive regulation of protein metabolic processGO:00512471280.018
cytoplasmic transportGO:00164821300.018
positive regulation of phosphate metabolic processGO:00459371390.018
negative regulation of nitrogen compound metabolic processGO:00511722650.018
positive regulation of multicellular organismal processGO:00512401430.018
actin filament organizationGO:00070151260.017
negative regulation of chromosome organizationGO:2001251190.017
tissue morphogenesisGO:00487292970.017
regulation of cellular amino acid metabolic processGO:000652100.017
actin cytoskeleton organizationGO:00300362060.017
negative regulation of signal transductionGO:00099682060.017
negative regulation of signalingGO:00230572190.017
regulation of ras protein signal transductionGO:0046578930.017
positive regulation of catabolic processGO:00098961050.017
negative regulation of cellular protein metabolic processGO:0032269850.017
nuclear divisionGO:00002803320.017
epithelial cell developmentGO:00020642740.017
protein transportGO:00150311550.017
mitotic g2 m transition checkpointGO:0044818700.017
negative regulation of multicellular organismal processGO:00512411420.017
modification dependent protein catabolic processGO:0019941780.017
ribonucleoprotein complex subunit organizationGO:0071826280.017
regulation of meiosisGO:004002030.017
regulation of multi organism processGO:00439001310.017
cell projection assemblyGO:0030031940.017
mrna splicing via spliceosomeGO:0000398730.016
ventral furrow formationGO:0007370170.016
locomotory behaviorGO:00076261760.016
organic cyclic compound catabolic processGO:19013611680.016
positive regulation of developmental processGO:00510941430.016
regulation of cellular amine metabolic processGO:003323830.016
single organism intracellular transportGO:19025822070.016
signal transduction by phosphorylationGO:00230141070.016
tissue migrationGO:00901301550.016
cellular response to organic substanceGO:00713101320.016
negative regulation of nucleic acid templated transcriptionGO:19035072400.016
positive regulation of erk1 and erk2 cascadeGO:0070374360.016
cellular nitrogen compound catabolic processGO:00442701650.016
negative regulation of cell proliferationGO:0008285690.016
germ line stem cell maintenanceGO:0030718500.016
determination of adult lifespanGO:00083401370.016
regulation of developmental growthGO:00486381740.016
gastrulation with mouth forming firstGO:0001703360.016
regulation of cell morphogenesisGO:00226041630.016
retina morphogenesis in camera type eyeGO:006004220.016
regulation of chromatin modificationGO:1903308280.016
regulation of protein modification processGO:00313991120.015
organ growthGO:0035265560.015
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:0031145300.015
negative regulation of catabolic processGO:0009895360.015
positive regulation of phosphorus metabolic processGO:00105621390.015
nucleobase containing compound transportGO:0015931560.015
nucleoside phosphate metabolic processGO:00067531620.015
establishment of protein localizationGO:00451841630.015
leg disc developmentGO:0035218920.015
secretionGO:00469031090.015
regulation of rna splicingGO:0043484690.015
nitrogen compound transportGO:0071705850.015
larval developmentGO:00021641040.015
dendrite morphogenesisGO:00488131990.015
posttranscriptional regulation of gene expressionGO:00106081450.015
programmed cell deathGO:00125012570.015
regulation of cell developmentGO:00602842150.015
regulation of phosphorylationGO:00423251470.015
positive regulation of cellular protein metabolic processGO:00322701180.015
regulation of transportGO:00510491810.015
regulation of nuclear divisionGO:0051783580.015
single organism carbohydrate metabolic processGO:0044723720.015
mitotic spindle checkpointGO:0071174110.015
histone modificationGO:00165701060.014
leucine importGO:006035630.014
mitotic nuclear divisionGO:00070672130.014
response to biotic stimulusGO:00096072940.014
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.014
metaphase anaphase transition of mitotic cell cycleGO:0007091280.014
ribonucleoside metabolic processGO:00091191270.014
negative regulation of mitotic cell cycle phase transitionGO:19019911030.014
positive regulation of intracellular signal transductionGO:19025331160.014
digestive tract developmentGO:00485651490.014
cilium organizationGO:0044782410.014
mitotic sister chromatid segregationGO:0000070870.014
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.014
spinal cord developmentGO:002151010.014
chromatin remodelingGO:0006338720.014
regulation of programmed cell deathGO:00430671520.014
regulation of localizationGO:00328792750.014
negative regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032435160.014
chromosome separationGO:0051304420.014
nucleotide metabolic processGO:00091171610.014
ribose phosphate metabolic processGO:00196931450.013
positive regulation of developmental growthGO:0048639620.013
sister chromatid segregationGO:0000819920.013
cellular response to chemical stimulusGO:00708871990.013
germarium derived egg chamber formationGO:00072931010.013
purine containing compound metabolic processGO:00725211550.013
cell adhesionGO:00071551360.013
purine ribonucleoside catabolic processGO:00461301120.013
response to insulinGO:0032868290.013
alternative mrna splicing via spliceosomeGO:0000380600.013
photoreceptor cell differentiationGO:00465301700.013
compound eye photoreceptor cell differentiationGO:00017511400.013
dendrite developmentGO:00163582040.013
stem cell proliferationGO:0072089880.013
epithelial cell differentiationGO:00308553220.013
protein phosphorylationGO:00064681690.013
nucleoside triphosphate metabolic processGO:00091411200.013
mrna transportGO:0051028150.013
dna damage checkpointGO:0000077780.013
single organism cellular localizationGO:19025801800.013
positive regulation of apoptotic signaling pathwayGO:200123540.013
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.013
camera type eye morphogenesisGO:004859320.013
regulation of cell deathGO:00109411730.013
heparan sulfate proteoglycan metabolic processGO:0030201100.013
positive regulation of mapk cascadeGO:0043410630.012
molting cycle chitin based cuticleGO:0007591560.012
negative regulation of dna dependent dna replicationGO:200010420.012
peptidyl threonine phosphorylationGO:001810720.012
nuclear exportGO:0051168240.012
regulation of erk1 and erk2 cascadeGO:0070372390.012
positive regulation of cell motilityGO:200014730.012
leg disc morphogenesisGO:0007478800.012
dna integrity checkpointGO:0031570810.012
regulation of embryonic developmentGO:0045995680.012
regulation of response to stressGO:00801342000.012
ameboidal type cell migrationGO:00016671510.012
intracellular protein transportGO:00068861040.012
agingGO:00075681430.012
molting cycleGO:0042303560.012
adult behaviorGO:00305341370.012
mapk cascadeGO:00001651070.012
multi organism reproductive behaviorGO:00447051210.012
salivary gland developmentGO:00074311620.012
regulation of molecular functionGO:00650092170.012
regulation of pathway restricted smad protein phosphorylationGO:006039310.012
positive regulation of phosphorylationGO:0042327870.012
chemosensory behaviorGO:00076351060.012
developmental maturationGO:00217001720.012
axon developmentGO:00615642970.011
gastrulationGO:0007369700.011
regulation of growthGO:00400082330.011
negative regulation of transcription dna templatedGO:00458922370.011
epithelial tube morphogenesisGO:0060562880.011
heterochromatin organizationGO:0070828250.011
regulation of transcription by chromatin organizationGO:003440130.011
humoral immune responseGO:00069591170.011
neuron projection guidanceGO:00974852410.011
cell motilityGO:00488702510.011
regulation of catalytic activityGO:00507901850.011
exocrine system developmentGO:00352721620.011
head developmentGO:00603221350.011
mesenchymal cell differentiationGO:004876210.011
regulation of nucleotide metabolic processGO:0006140620.011
organonitrogen compound biosynthetic processGO:19015661170.011
negative regulation of cell communicationGO:00106482230.011
immune effector processGO:0002252980.011
negative regulation of chromosome segregationGO:0051985140.011
somatic stem cell divisionGO:0048103370.011
developmental programmed cell deathGO:00106231380.011
regulation of synapse assemblyGO:0051963940.011
regulation of cellular localizationGO:00603411360.011
open tracheal system developmentGO:00074242040.011
positive regulation of rna biosynthetic processGO:19026802660.011
Rat
cellular response to nitrogen compoundGO:1901699510.011
gene silencing by mirnaGO:0035195220.011
eye photoreceptor cell differentiationGO:00017541450.011
positive regulation of growthGO:0045927750.011
nucleoside metabolic processGO:00091161270.011
purine nucleoside triphosphate metabolic processGO:00091441190.011
brain developmentGO:00074201200.011
response to extracellular stimulusGO:00099911160.011
regulation of translationGO:0006417560.011
nucleobase containing small molecule metabolic processGO:00550861740.011
establishment of organelle localizationGO:00516561220.011
cell fate determinationGO:0001709910.011
rhythmic processGO:00485111060.011
regulation of imaginal disc growthGO:0045570260.011
regulation of synaptic growth at neuromuscular junctionGO:0008582890.011
regulation of synapse structure and activityGO:00508031280.011
multicellular organismal agingGO:00102591400.011
cell agingGO:000756920.011
ribonucleotide metabolic processGO:00092591450.011
mesenchymal cell developmentGO:001403110.011
kidney developmentGO:000182230.011
regulation of cell projection organizationGO:0031344920.011
defense responseGO:00069523000.011
chromosome segregationGO:00070591570.011
purine ribonucleotide metabolic processGO:00091501450.010
regulation of cellular ketone metabolic processGO:001056530.010
imaginal disc derived wing vein specificationGO:0007474480.010
mesoderm developmentGO:0007498780.010
cilium morphogenesisGO:0060271390.010
negative regulation of proteasomal protein catabolic processGO:1901799160.010
tissue deathGO:00162711020.010
lipid metabolic processGO:00066291210.010

TfIIS disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.036
musculoskeletal system diseaseDOID:1700.023
disease of cellular proliferationDOID:1456600.017
disease of metabolismDOID:001466700.016
nervous system diseaseDOID:86300.014
organ system cancerDOID:005068600.011
cancerDOID:16200.011