Drosophila melanogaster

39 known processes

Sply (Dmel_CG8946)

Sphingosine-1-phosphate lyase

(Aliases: l(2)05091,spl,anon-WO0142479.5,SPL,sply,Spl,CG8946,Dmel\CG8946)

Sply biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
ion transportGO:00068111450.268
single organism behaviorGO:00447083910.238
organic substance transportGO:00717022570.178
anion transportGO:0006820410.119
homeostatic processGO:00425921990.119
regionalizationGO:00030024160.117
imaginal disc derived appendage developmentGO:00487373990.106
cation transportGO:00068121100.100
embryo development ending in birth or egg hatchingGO:00097921520.098
embryonic development via the syncytial blastodermGO:00017001480.079
cell cell signaling involved in cell fate commitmentGO:00451682100.073
chemical homeostasisGO:0048878920.068
adult somatic muscle developmentGO:0007527140.065
organic acid transportGO:0015849180.053
positive regulation of multicellular organismal processGO:00512401430.053
amino acid transportGO:0006865120.052
multicellular organism growthGO:0035264460.050
Mouse
vesicle mediated transportGO:00161923810.049
embryonic morphogenesisGO:00485982060.045
immune system processGO:00023763470.044
Mouse
regulation of cell deathGO:00109411730.044
neuron recognitionGO:00080381010.043
positive regulation of growthGO:0045927750.043
epithelial cell differentiationGO:00308553220.041
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.041
positive regulation of developmental growthGO:0048639620.040
organic anion transportGO:0015711280.039
positive regulation of protein secretionGO:005071490.038
digestive tract morphogenesisGO:00485461270.037
gastrulationGO:0007369700.037
imaginal disc derived wing morphogenesisGO:00074763370.037
eye developmentGO:00016543230.037
nitrogen compound transportGO:0071705850.037
protein localizationGO:00081042840.037
lateral inhibitionGO:00463312060.035
negative regulation of cellular metabolic processGO:00313243820.034
positive regulation of cell motilityGO:200014730.033
intracellular transportGO:00469072280.032
regulation of reproductive processGO:2000241540.032
digestive system developmentGO:00551231490.032
detection of light stimulusGO:0009583580.031
epithelial tube morphogenesisGO:0060562880.030
chemosensory behaviorGO:00076351060.030
regulation of multicellular organismal developmentGO:20000264140.029
muscle structure developmentGO:00610612240.029
actin cytoskeleton organizationGO:00300362060.029
positive regulation of protein transportGO:0051222370.029
negative regulation of biosynthetic processGO:00098902770.028
digestive tract developmentGO:00485651490.028
regulation of multi organism processGO:00439001310.028
endocytosisGO:00068973100.027
programmed cell deathGO:00125012570.027
tube morphogenesisGO:00352391910.027
dorsal appendage formationGO:0046843470.026
ion homeostasisGO:0050801550.025
metal ion transportGO:0030001740.025
response to abiotic stimulusGO:00096283410.025
single organism biosynthetic processGO:00447112060.024
tube developmentGO:00352952440.024
phosphatidic acid metabolic processGO:004647310.024
cellular cation homeostasisGO:0030003380.023
wing disc morphogenesisGO:00074723440.023
cell deathGO:00082192790.023
positive regulation of developmental processGO:00510941430.023
establishment of localization in cellGO:00516494020.023
response to woundingGO:0009611940.022
positive regulation of cell migrationGO:003033520.022
regulation of cellular localizationGO:00603411360.021
positive regulation of phosphate metabolic processGO:00459371390.021
cytoplasmic transportGO:00164821300.021
regulation of cellular component biogenesisGO:00440872010.021
positive regulation of transportGO:0051050920.021
regulation of growthGO:00400082330.020
Mouse
neutral lipid metabolic processGO:0006638120.020
adult behaviorGO:00305341370.020
phosphate ion transportGO:000681740.020
disaccharide metabolic processGO:000598440.020
morphogenesis of an epitheliumGO:00020092760.020
deathGO:00162652840.020
developmental growthGO:00485892800.020
Mouse
wnt signaling pathwayGO:0016055980.019
protein complex assemblyGO:00064612000.019
regulation of metal ion transportGO:0010959150.019
protein transportGO:00150311550.019
tissue morphogenesisGO:00487292970.019
negative regulation of cellular biosynthetic processGO:00313272770.019
segmentationGO:00352822070.018
growthGO:00400073590.018
Mouse
glycosyl compound metabolic processGO:19016571270.018
phagocytosisGO:00069092150.018
single organism intracellular transportGO:19025822070.017
imaginal disc derived appendage morphogenesisGO:00351143950.017
intracellular protein transportGO:00068861040.017
notch signaling pathwayGO:00072191200.017
establishment of protein localizationGO:00451841630.017
organonitrogen compound catabolic processGO:19015651280.017
respiratory system developmentGO:00605412130.017
positive regulation of multicellular organism growthGO:0040018210.016
post embryonic appendage morphogenesisGO:00351203850.016
connective tissue developmentGO:006144830.016
leg disc developmentGO:0035218920.016
regulation of protein localizationGO:0032880760.016
positive regulation of cell communicationGO:00106472500.015
nucleoside phosphate metabolic processGO:00067531620.015
response to hexoseGO:000974630.015
response to oxygen levelsGO:0070482590.015
columnar cuboidal epithelial cell developmentGO:00020662490.015
carboxylic acid transportGO:0046942180.015
cellular protein modification processGO:00064644380.015
macromolecular complex assemblyGO:00650032560.015
signal transduction by phosphorylationGO:00230141070.015
protein secretionGO:0009306450.015
nucleoside metabolic processGO:00091161270.015
nucleobase containing small molecule metabolic processGO:00550861740.015
negative regulation of rna biosynthetic processGO:19026792400.015
positive regulation of signalingGO:00230562430.014
secretionGO:00469031090.014
purine ribonucleoside metabolic processGO:00461281270.014
developmental programmed cell deathGO:00106231380.014
response to metal ionGO:0010038230.014
cellular homeostasisGO:0019725800.014
gland developmentGO:00487321910.014
organelle assemblyGO:00709251980.014
regulation of intracellular transportGO:0032386640.014
autophagyGO:00069141080.014
phosphatidylinositol 3 kinase signalingGO:001406540.014
gastrulation involving germ band extensionGO:0010004360.014
camera type eye developmentGO:004301040.013
protein complex biogenesisGO:00702712010.013
positive regulation of cellular component organizationGO:00511301560.013
response to hypoxiaGO:0001666530.013
cellular component assembly involved in morphogenesisGO:00109271510.013
positive regulation of macromolecule biosynthetic processGO:00105572830.013
cellular macromolecule localizationGO:00707272200.013
striated muscle myosin thick filament assemblyGO:007168830.013
regulation of cell cycleGO:00517262910.013
actin filament based processGO:00300292200.013
cellular macromolecular complex assemblyGO:00346221530.013
oxoacid metabolic processGO:00434361030.013
morphogenesis of a branching epitheliumGO:0061138450.013
germ band shorteningGO:0007390190.012
regulation of transportGO:00510491810.012
response to lipopolysaccharideGO:003249640.012
cellular catabolic processGO:00442483720.012
cellular protein localizationGO:00346131600.012
epithelial cell developmentGO:00020642740.012
generation of precursor metabolites and energyGO:0006091420.012
gonad developmentGO:0008406500.012
Mouse
regulation of catabolic processGO:00098941700.011
detection of abiotic stimulusGO:0009582660.011
regulation of notch signaling pathwayGO:00085931000.011
positive regulation of reproductive processGO:200024370.011
mitochondrion organizationGO:0007005650.011
response to glucoseGO:000974920.011
organic acid metabolic processGO:00060821030.011
regulation of cell developmentGO:00602842150.011
regulation of molecular functionGO:00650092170.011
cellular response to hexose stimulusGO:007133110.011
cellular amino acid metabolic processGO:0006520610.011
positive regulation of nfat protein import into nucleusGO:0051533160.011
protein localization to organelleGO:0033365820.011
appendage developmentGO:00487364010.011
mesenchymal cell developmentGO:001403110.010
response to copper ionGO:004668840.010
endomembrane system organizationGO:00102561190.010
transcription from rna polymerase ii promoterGO:00063663680.010
phosphatidylinositol mediated signalingGO:004801540.010
regulation of phosphatidylinositol 3 kinase signalingGO:001406640.010
maintenance of locationGO:0051235730.010
ras protein signal transductionGO:0007265880.010
catabolic processGO:00090564090.010
purine nucleoside metabolic processGO:00422781270.010

Sply disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.028
disease of metabolismDOID:001466700.021
musculoskeletal system diseaseDOID:1700.014
inherited metabolic disorderDOID:65500.012