Drosophila melanogaster

41 known processes

ort (Dmel_CG7411)

ora transientless

(Aliases: HisCl,hisCl2,DmHisCl2,GluCI,Hist1,Ort,Dm-hclA,Dmel\CG7411,hclA,HisCI2,DMHisClalpha1,HisCl2,ora,CG7411)

ort biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
neurological system processGO:00508773580.855
Fly
sensory perceptionGO:00076001960.806
adult behaviorGO:00305341370.747
synaptic transmissionGO:00072682880.375
ion transmembrane transportGO:00342201220.280
response to toxic substanceGO:0009636220.275
sensory perception of light stimulusGO:0050953120.246
response to abiotic stimulusGO:00096283410.193
ion transportGO:00068111450.192
single organism behaviorGO:00447083910.181
cognitionGO:00508901410.149
Fly
regulation of cellular amino acid metabolic processGO:000652100.137
developmental pigmentationGO:0048066680.131
deathGO:00162652840.129
detection of stimulusGO:00516061560.113
response to organic substanceGO:00100332840.110
oxoacid metabolic processGO:00434361030.106
detection of external stimulusGO:0009581660.101
response to oxygen containing compoundGO:19017002000.100
locomotory behaviorGO:00076261760.099
learning or memoryGO:00076111410.088
Fly
adult locomotory behaviorGO:0008344760.087
positive regulation of signalingGO:00230562430.084
blood circulationGO:0008015260.083
multi multicellular organism processGO:00447061230.077
cellular ketone metabolic processGO:0042180240.075
apoptotic processGO:00069151590.075
small molecule metabolic processGO:00442813050.074
intracellular signal transductionGO:00355563000.070
sensory perception of smellGO:0007608800.069
cation transportGO:00068121100.066
cellular lipid metabolic processGO:0044255830.065
sensory perception of chemical stimulusGO:00076061160.065
response to light stimulusGO:00094161240.064
purine ribonucleoside metabolic processGO:00461281270.062
pigmentationGO:0043473750.061
visual perceptionGO:000760190.060
eye morphogenesisGO:00485922600.060
detection of abiotic stimulusGO:0009582660.060
detection of light stimulusGO:0009583580.059
photoreceptor cell differentiationGO:00465301700.057
photoreceptor cell developmentGO:0042461960.056
cellular response to chemical stimulusGO:00708871990.055
oxidation reduction processGO:00551141230.055
positive regulation of cell communicationGO:00106472500.052
anion homeostasisGO:005508130.052
organic hydroxy compound metabolic processGO:1901615830.052
thermotaxisGO:0043052160.051
positive regulation of nucleobase containing compound metabolic processGO:00459353320.051
detection of visible lightGO:0009584380.049
regulation of localizationGO:00328792750.048
metal ion transportGO:0030001740.048
cell deathGO:00082192790.047
positive regulation of catabolic processGO:00098961050.046
cellular cation homeostasisGO:0030003380.045
catabolic processGO:00090564090.045
amine metabolic processGO:0009308120.043
g protein coupled receptor signaling pathwayGO:00071861360.043
response to organophosphorusGO:004668320.042
programmed cell deathGO:00125012570.042
purine nucleotide metabolic processGO:00061631460.040
cuticle developmentGO:0042335860.040
endocytosisGO:00068973100.039
positive regulation of nitrogen compound metabolic processGO:00511733540.039
organic substance catabolic processGO:19015753080.038
regulation of intracellular signal transductionGO:19025312360.038
nucleobase containing small molecule metabolic processGO:00550861740.037
transmembrane transportGO:00550851390.037
response to temperature stimulusGO:00092661060.037
purine nucleoside triphosphate catabolic processGO:00091461080.036
cation transmembrane transportGO:0098655880.035
embryo development ending in birth or egg hatchingGO:00097921520.035
nucleoside phosphate metabolic processGO:00067531620.034
cellular response to carbohydrate stimulusGO:007132240.034
aromatic compound catabolic processGO:00194391660.034
chemotaxisGO:00069352490.033
organonitrogen compound metabolic processGO:19015643180.032
purine ribonucleotide catabolic processGO:00091541090.031
regulation of cell differentiationGO:00455953020.031
regulation of apoptotic processGO:00429811300.030
defense responseGO:00069523000.030
dna metabolic processGO:00062592270.030
single organism biosynthetic processGO:00447112060.030
taxisGO:00423303040.030
positive regulation of purine nucleotide metabolic processGO:1900544550.030
divalent metal ion transportGO:0070838260.029
regulation of anatomical structure morphogenesisGO:00226032420.029
immune response regulating signaling pathwayGO:000276420.029
immune system processGO:00023763470.029
positive regulation of signal transductionGO:00099672230.028
cellular catabolic processGO:00442483720.028
negative regulation of cell communicationGO:00106482230.028
Fly
regulation of epithelial cell proliferationGO:005067840.027
organophosphate metabolic processGO:00196371950.027
positive regulation of response to stimulusGO:00485843230.027
lipid metabolic processGO:00066291210.027
vitamin biosynthetic processGO:000911010.027
regulation of cell deathGO:00109411730.026
isoprenoid metabolic processGO:000672080.026
purine containing compound catabolic processGO:00725231120.026
fat soluble vitamin metabolic processGO:000677510.026
positive regulation of macromolecule metabolic processGO:00106044050.026
ribonucleoside triphosphate metabolic processGO:00091991190.026
negative regulation of signalingGO:00230572190.026
Fly
neuromuscular junction developmentGO:00075281490.025
ribonucleoside catabolic processGO:00424541120.025
cellular response to dna damage stimulusGO:00069742230.025
neuron recognitionGO:00080381010.025
transcription from rna polymerase ii promoterGO:00063663680.025
organic cyclic compound catabolic processGO:19013611680.025
regulation of secretion by cellGO:1903530390.025
regulation of cellular component biogenesisGO:00440872010.024
growthGO:00400073590.024
cellular amino acid metabolic processGO:0006520610.024
positive regulation of nucleoside metabolic processGO:0045979470.024
regulation of multicellular organismal developmentGO:20000264140.024
eye developmentGO:00016543230.024
nucleoside metabolic processGO:00091161270.023
membrane depolarizationGO:005189940.023
vesicle mediated transportGO:00161923810.023
regulation of catabolic processGO:00098941700.023
compound eye photoreceptor developmentGO:0042051780.022
sleepGO:0030431490.022
Fly
establishment of localization in cellGO:00516494020.022
terpenoid metabolic processGO:000672170.021
regulation of multi organism processGO:00439001310.021
immune response activating signal transductionGO:000275720.021
fat soluble vitamin biosynthetic processGO:004236210.021
cellular response to organonitrogen compoundGO:0071417360.021
signal releaseGO:0023061490.021
positive regulation of multicellular organismal processGO:00512401430.021
cellular response to insulin stimulusGO:0032869280.021
purine ribonucleoside triphosphate metabolic processGO:00092051190.021
carbohydrate derivative biosynthetic processGO:1901137850.021
purine ribonucleotide metabolic processGO:00091501450.020
ribonucleotide catabolic processGO:00092611090.020
negative regulation of gene expressionGO:00106293870.020
negative regulation of developmental processGO:00510932010.020
purine nucleoside metabolic processGO:00422781270.020
immune responseGO:00069552460.020
developmental growthGO:00485892800.020
regulation of anatomical structure sizeGO:00900661630.020
organonitrogen compound biosynthetic processGO:19015661170.020
positive regulation of gene expressionGO:00106282900.020
response to radiationGO:00093141550.019
sensory perception of soundGO:0007605560.019
gene silencingGO:00164581380.019
compound eye developmentGO:00487493070.019
regulation of retinal cell programmed cell deathGO:0046668180.019
response to heatGO:0009408630.019
regulation of hormone levelsGO:0010817400.019
regulation of synaptic transmissionGO:0050804690.019
Fly
positive regulation of cellular biosynthetic processGO:00313283160.019
male courtship behavior veined wing vibrationGO:0016545210.019
positive regulation of nucleic acid templated transcriptionGO:19035082660.019
vitamin metabolic processGO:000676620.019
calcium ion transportGO:0006816240.019
negative regulation of cellular metabolic processGO:00313243820.018
nucleobase containing compound catabolic processGO:00346551650.018
positive regulation of developmental growthGO:0048639620.018
salivary gland morphogenesisGO:00074351450.018
nucleoside phosphate biosynthetic processGO:1901293340.018
cellular response to growth factor stimulusGO:0071363300.018
organic acid metabolic processGO:00060821030.018
dorsal ventral axis specificationGO:0009950660.017
nucleotide metabolic processGO:00091171610.017
response to other organismGO:00517072930.017
response to insulinGO:0032868290.017
response to lipopolysaccharideGO:003249640.017
camera type eye morphogenesisGO:004859320.017
purine nucleoside triphosphate metabolic processGO:00091441190.017
heterocycle catabolic processGO:00467001660.017
light induced release of internally sequestered calcium ionGO:000837710.017
compound eye retinal cell programmed cell deathGO:0046667230.017
negative regulation of signal transductionGO:00099682060.016
organophosphate catabolic processGO:00464341120.016
regulation of response to stressGO:00801342000.016
double strand break repairGO:0006302260.016
carboxylic acid metabolic processGO:0019752920.016
negative regulation of multicellular organismal processGO:00512411420.016
homeostatic processGO:00425921990.016
hormone metabolic processGO:0042445330.016
cell recognitionGO:00080371020.016
enzyme linked receptor protein signaling pathwayGO:00071671790.015
cellular nitrogen compound catabolic processGO:00442701650.015
nucleoside triphosphate catabolic processGO:00091431080.015
purine containing compound metabolic processGO:00725211550.015
circadian behaviorGO:0048512760.015
Fly
meiotic chromosome segregationGO:0045132590.015
detection of stimulus involved in sensory perceptionGO:0050906920.015
lipid biosynthetic processGO:0008610460.015
cellular amine metabolic processGO:0044106120.015
positive regulation of immune responseGO:0050778630.015
regulation of immune system processGO:00026821760.015
regulation of behaviorGO:0050795750.015
Fly
carbohydrate derivative catabolic processGO:19011361180.014
response to endogenous stimulusGO:00097191190.014
small molecule biosynthetic processGO:0044283370.014
larval developmentGO:00021641040.014
retina development in camera type eyeGO:006004140.014
connective tissue developmentGO:006144830.014
regulation of insulin receptor signaling pathwayGO:0046626170.014
cell adhesionGO:00071551360.014
reproductive behaviorGO:00190981220.014
anatomical structure homeostasisGO:0060249970.014
cellular aldehyde metabolic processGO:0006081100.014
regulation of cell developmentGO:00602842150.014
compound eye morphogenesisGO:00017452490.014
regulation of phosphatase activityGO:001092130.014
anion transportGO:0006820410.014
cellular response to decreased oxygen levelsGO:0036294300.014
regulation of cellular amine metabolic processGO:003323830.013
positive regulation of phosphate metabolic processGO:00459371390.013
regulation of cell morphogenesis involved in differentiationGO:0010769610.013
organonitrogen compound catabolic processGO:19015651280.013
regulation of hydrolase activityGO:0051336970.013
regulation of protein metabolic processGO:00512462560.013
regulation of membrane potentialGO:0042391350.013
response to alcoholGO:0097305950.013
nucleoside triphosphate metabolic processGO:00091411200.013
organelle assemblyGO:00709251980.013
regulation of cytoskeleton organizationGO:0051493890.013
positive regulation of cellular catabolic processGO:0031331950.013
purine ribonucleoside catabolic processGO:00461301120.013
rho protein signal transductionGO:0007266140.013
intrinsic apoptotic signaling pathwayGO:0097193160.012
negative regulation of cell deathGO:0060548810.012
phosphatidylinositol mediated signalingGO:004801540.012
nucleotide catabolic processGO:00091661090.012
insulin receptor signaling pathwayGO:0008286250.012
regulation of catalytic activityGO:00507901850.012
cellular response to radiationGO:0071478520.012
protein complex biogenesisGO:00702712010.012
negative regulation of intracellular signal transductionGO:1902532570.012
lipopolysaccharide mediated signaling pathwayGO:003166310.012
regulation of cell cycleGO:00517262910.012
regulation of phosphorus metabolic processGO:00511742100.012
rhodopsin mediated signaling pathwayGO:0016056210.012
insecticide catabolic processGO:004670110.012
chemical homeostasisGO:0048878920.012
regulation of phosphorylationGO:00423251470.012
male courtship behavior veined wing generated song productionGO:0045433200.012
eye photoreceptor cell developmentGO:0042462810.011
meiotic cell cycle processGO:19030461320.011
multicellular organismal agingGO:00102591400.011
nucleoside phosphate catabolic processGO:19012921100.011
regulation of cellular ketone metabolic processGO:001056530.011
regulation of cellular catabolic processGO:00313291570.011
immune system developmentGO:0002520570.011
regulation of cellular response to stressGO:0080135890.011
nucleoside catabolic processGO:00091641120.011
phagocytosisGO:00069092150.011
forebrain developmentGO:003090020.011
pigment metabolic process involved in developmental pigmentationGO:0043324330.011
maintenance of locationGO:0051235730.011
organic hydroxy compound biosynthetic processGO:1901617210.011
ribose phosphate metabolic processGO:00196931450.011
positive regulation of gtpase activityGO:0043547430.011
positive regulation of transcription dna templatedGO:00458932660.011
oocyte maturationGO:000155630.011
secretion by cellGO:00329401010.011
cell migrationGO:00164772380.010
regulation of system processGO:0044057360.010
Fly
purine nucleotide catabolic processGO:00061951090.010
response to organonitrogen compoundGO:0010243750.010
adaptation of rhodopsin mediated signalingGO:001606230.010
response to ethanolGO:0045471590.010
response to inorganic substanceGO:0010035440.010
digestive tract morphogenesisGO:00485461270.010
positive regulation of response to biotic stimulusGO:0002833310.010

ort disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
artery diseaseDOID:005082800.063
cardiovascular system diseaseDOID:128700.063
vascular diseaseDOID:17800.063
disease of anatomical entityDOID:700.063
hypertensionDOID:1076300.013